CY1112815T1 - Ανταγωνιστες υποδοχεα ορμονης απελευθερωσης γοναδοτροπινης και μεθοδοι που σχετιζονται με αυτους - Google Patents

Ανταγωνιστες υποδοχεα ορμονης απελευθερωσης γοναδοτροπινης και μεθοδοι που σχετιζονται με αυτους

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Publication number
CY1112815T1
CY1112815T1 CY20121100499T CY121100499T CY1112815T1 CY 1112815 T1 CY1112815 T1 CY 1112815T1 CY 20121100499 T CY20121100499 T CY 20121100499T CY 121100499 T CY121100499 T CY 121100499T CY 1112815 T1 CY1112815 T1 CY 1112815T1
Authority
CY
Cyprus
Prior art keywords
methods
competitives
gonadotropine
hormones
pharmaceutically acceptable
Prior art date
Application number
CY20121100499T
Other languages
English (en)
Inventor
Yun-Fei Zhu
Chen Chen
Fabio C Tucci
Zhiqiang Guo
Timothy D Gross
Martin Rowbottom
R Scott Struthers
Original Assignee
Neurocrine Biosciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences, Inc. filed Critical Neurocrine Biosciences, Inc.
Publication of CY1112815T1 publication Critical patent/CY1112815T1/el

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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Ανταγωνιστές υποδοχέα GnRΗ αποκαλύπτονται που έχουν χρησιμότητα στη θεραπεία μιας ποικιλίας καταστάσεων που σχετίζονται με ορμόνες του φύλου τόσο σε άνδρες όσο και σε γυναίκες. Οι ενώσεις αυτής της εφεύρεσης είναι του τύπου (Ι) όπου τα Α, Q, R1, R2, R3a, R3b, R4, R5, R6 και n είναι όπως ορίζονται εδώ, συμπεριλαμβανομένων στερεοϊσομερών, προφαρμάκων και φαρμακευτικώς αποδεκτών αλάτων αυτών. Επίσης αποκαλύπτονται συνθέσεις που περιέχουν μια ένωση αυτής της εφεύρεσης σε συνδυασμό με έναν φαρμακευτικώς αποδεκτό φορέα, όπως επίσης και μεθόδους που σχετίζονται με τη χρήση αυτών για ανταγωνισμό ορμόνης απελευθέρωσης γοναδοτροπίνης σε ένα άτομο που χρειάζεται κάτι τέτοιο.
CY20121100499T 2000-01-25 2012-06-01 Ανταγωνιστες υποδοχεα ορμονης απελευθερωσης γοναδοτροπινης και μεθοδοι που σχετιζονται με αυτους CY1112815T1 (el)

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