CY1110706T1 - Αντιβακτηριδιακα παραγωγα κινολινης - Google Patents
Αντιβακτηριδιακα παραγωγα κινολινηςInfo
- Publication number
- CY1110706T1 CY1110706T1 CY20101100708T CY101100708T CY1110706T1 CY 1110706 T1 CY1110706 T1 CY 1110706T1 CY 20101100708 T CY20101100708 T CY 20101100708T CY 101100708 T CY101100708 T CY 101100708T CY 1110706 T1 CY1110706 T1 CY 1110706T1
- Authority
- CY
- Cyprus
- Prior art keywords
- compounds
- preparation
- pharmaceutically acceptable
- treatment
- kinolin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται σε νέα παράγωγα υποκατεστημένης κινολίνης σύμφωνα με το γενικό τύπο (la) ή τον τύπο (lb): περιλαμβανομένων οποιωνδήποτε στερεοχημικά ισομερών μορφών αυτών, ενός φαρμακευτικά αποδεκτού άλατος αυτών, μίας μορφής Ν-οξειδίου αυτών ή ενός επιδιαλυτωμένου άλατος αυτών. Οι ενώσεις που αξιώνονται είναι χρήσιμες για τη θεραπεία μίας βακτηριδιακής μόλυνσης. Επίσης αξιώνεται μία σύνθεση που περιλαμβάνει ένα φαρμακευτικά αποδεκτό φορέα και, ως ενεργό συστατικό, μία θεραπευτικά αποτελεσματική ποσότητα των αξιωνώμενων ενώσεων, η χρήση των αξιωνώμενων ενώσεων ή σύνθετων ιόντων για την παρασκευή ενός φαρμακευτικού μέσου για τη θεραπεία μίας βακτηριδιακής μόλυνσης και μία διεργασία για την παρασκευή των αξιωνώμενων ενώσεων.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06125521 | 2006-12-06 | ||
| EP07847813A EP2086941B1 (en) | 2006-12-06 | 2007-12-04 | Antibacterial quinoline derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1110706T1 true CY1110706T1 (el) | 2015-06-10 |
Family
ID=37944337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20101100708T CY1110706T1 (el) | 2006-12-06 | 2010-07-28 | Αντιβακτηριδιακα παραγωγα κινολινης |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7998979B2 (el) |
| EP (1) | EP2086941B1 (el) |
| JP (1) | JP5356245B2 (el) |
| KR (1) | KR101490221B1 (el) |
| CN (1) | CN101541752B (el) |
| AR (1) | AR064150A1 (el) |
| AT (1) | ATE465994T1 (el) |
| AU (1) | AU2007328889B2 (el) |
| BR (1) | BRPI0720251B8 (el) |
| CA (1) | CA2668520C (el) |
| CL (1) | CL2007003516A1 (el) |
| CY (1) | CY1110706T1 (el) |
| DE (1) | DE602007006231D1 (el) |
| DK (1) | DK2086941T3 (el) |
| ES (1) | ES2344535T3 (el) |
| HK (1) | HK1137428A1 (el) |
| HR (1) | HRP20100384T1 (el) |
| IL (1) | IL199081A (el) |
| JO (1) | JO2685B1 (el) |
| ME (1) | ME01073B (el) |
| MX (1) | MX2009005980A (el) |
| NO (1) | NO341995B1 (el) |
| NZ (1) | NZ576673A (el) |
| PL (1) | PL2086941T3 (el) |
| PT (1) | PT2086941E (el) |
| RS (1) | RS51390B (el) |
| RU (1) | RU2446159C2 (el) |
| SI (1) | SI2086941T1 (el) |
| TW (1) | TWI412364B (el) |
| WO (1) | WO2008068269A1 (el) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA038350B1 (ru) | 2012-04-27 | 2021-08-12 | Янссен Фармацевтика Нв | Антибактериальные хинолиновые производные |
| ES2576491T3 (es) | 2012-04-27 | 2016-07-07 | Janssen Pharmaceutica, N.V. | Derivados de quinolina antibacterianos |
| CN104650054B (zh) * | 2013-11-25 | 2019-09-13 | 重庆医药工业研究院有限责任公司 | 一种抗结核菌的喹啉噻吩芳氧乙胺衍生物 |
| US11857352B2 (en) | 2016-09-06 | 2024-01-02 | The Research Foundation For The State University Of New York | Positron imaging tomography imaging agent composition and method for bacterial infection |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6033389B2 (ja) * | 1979-02-22 | 1985-08-02 | 日産化学工業株式会社 | 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤 |
| CA2270123A1 (en) | 1996-10-28 | 1998-05-07 | Department Of The Army, U.S. Government | Compounds, compositions and methods for treating antibiotic-resistant infections |
| MXPA04000968A (es) * | 2001-07-31 | 2005-02-17 | Univ Wayne State | Derivados de quinolina y uso de los mismos como agentes antitumor. |
| PL222801B1 (pl) | 2002-07-25 | 2016-09-30 | Janssen Pharmaceutica Nv | Pochodne chinoliny, ich zastosowanie, sposób ich wytwarzania oraz kompozycja farmaceutyczna zawierająca je |
| AP2188A (en) | 2004-01-23 | 2010-12-14 | Janssen Pharmaceutica Nv | Substituted quinolines and their use as mycobacterial inhibitors. |
| PT1711181E (pt) | 2004-01-23 | 2009-12-29 | Janssen Pharmaceutica Nv | Derivados quinolina e sua utilização como inibidores micobacterianos |
| AU2005210036B2 (en) * | 2004-01-29 | 2010-12-23 | Janssen Pharmaceutica N.V. | Quinoline derivatives for use as mycobacterial inhibitors |
| EP1753427B1 (en) * | 2004-05-28 | 2008-04-02 | Janssen Pharmaceutica N.V. | Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases |
| DK1797115T3 (en) | 2004-09-28 | 2017-10-02 | Janssen Pharmaceutica Nv | BACTERIAL ATP SYNTHASE BINDING DOMAIN. |
-
2007
- 2007-11-29 JO JO2007507A patent/JO2685B1/en active
- 2007-12-04 JP JP2009539740A patent/JP5356245B2/ja not_active Expired - Fee Related
- 2007-12-04 KR KR1020097012572A patent/KR101490221B1/ko active IP Right Grant
- 2007-12-04 PL PL07847813T patent/PL2086941T3/pl unknown
- 2007-12-04 BR BRPI0720251A patent/BRPI0720251B8/pt active IP Right Grant
- 2007-12-04 DK DK07847813.8T patent/DK2086941T3/da active
- 2007-12-04 MX MX2009005980A patent/MX2009005980A/es active IP Right Grant
- 2007-12-04 PT PT07847813T patent/PT2086941E/pt unknown
- 2007-12-04 CN CN2007800437666A patent/CN101541752B/zh active Active
- 2007-12-04 EP EP07847813A patent/EP2086941B1/en active Active
- 2007-12-04 ME MEP-2010-111A patent/ME01073B/me unknown
- 2007-12-04 DE DE602007006231T patent/DE602007006231D1/de active Active
- 2007-12-04 SI SI200730286T patent/SI2086941T1/sl unknown
- 2007-12-04 AT AT07847813T patent/ATE465994T1/de active
- 2007-12-04 RS RSP-2010/0340A patent/RS51390B/en unknown
- 2007-12-04 AU AU2007328889A patent/AU2007328889B2/en not_active Ceased
- 2007-12-04 US US12/516,370 patent/US7998979B2/en active Active
- 2007-12-04 WO PCT/EP2007/063315 patent/WO2008068269A1/en active Application Filing
- 2007-12-04 ES ES07847813T patent/ES2344535T3/es active Active
- 2007-12-04 NZ NZ576673A patent/NZ576673A/en unknown
- 2007-12-04 RU RU2009125525/04A patent/RU2446159C2/ru active
- 2007-12-04 CA CA2668520A patent/CA2668520C/en active Active
- 2007-12-05 AR ARP070105443A patent/AR064150A1/es unknown
- 2007-12-05 TW TW096146213A patent/TWI412364B/zh active
- 2007-12-05 CL CL200703516A patent/CL2007003516A1/es unknown
-
2009
- 2009-06-02 IL IL199081A patent/IL199081A/en active IP Right Grant
- 2009-07-06 NO NO20092540A patent/NO341995B1/no unknown
-
2010
- 2010-01-28 HK HK10100936.5A patent/HK1137428A1/xx not_active IP Right Cessation
- 2010-07-12 HR HR20100384T patent/HRP20100384T1/hr unknown
- 2010-07-28 CY CY20101100708T patent/CY1110706T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1117766T1 (el) | Αντιβακτηριδιακα παραγωγα κινολινης | |
| CY1111188T1 (el) | Αντιβακτηριακα παραγωγα κινολινης | |
| CY1110388T1 (el) | Χρηση υποκατεστημενων παραγωγων κουινολινης για τη θεραπευτικη αντιμετωπιση μυκοβακτηριακων ασθενειων ανθεκτικων σε φαρμακα | |
| CY1117247T1 (el) | Αντιβακτηριακα παραγωγα κινολινης | |
| CY1112230T1 (el) | Αντιβακτηριακα παραγωγα κινολινης | |
| CY1114384T1 (el) | Αντιβακτηριακα παραγωγα κινολινης | |
| CY1118515T1 (el) | Παραγωγα κινολινης ως αντιβακτηριακοι παραγοντες | |
| CY1110706T1 (el) | Αντιβακτηριδιακα παραγωγα κινολινης | |
| EA201491982A1 (ru) | Антибактериальные хинолиновые производные | |
| CY1112027T1 (el) | Αντιβακτηριακα παραγωγα κινολινης | |
| EA201491971A1 (ru) | Антибактериальные хинолиновые производные |