CY1110537T1 - Ενωσεις και μεθοδοι για την αγωγη της δυσλιπιδαιμιας - Google Patents

Ενωσεις και μεθοδοι για την αγωγη της δυσλιπιδαιμιας

Info

Publication number
CY1110537T1
CY1110537T1 CY20091101151T CY091101151T CY1110537T1 CY 1110537 T1 CY1110537 T1 CY 1110537T1 CY 20091101151 T CY20091101151 T CY 20091101151T CY 091101151 T CY091101151 T CY 091101151T CY 1110537 T1 CY1110537 T1 CY 1110537T1
Authority
CY
Cyprus
Prior art keywords
methods
unions
disease education
education
disease
Prior art date
Application number
CY20091101151T
Other languages
English (en)
Inventor
Guoqing Cao
Ana Maria Escribano
Maria Carmen Fernandez
Todd Fields
Douglas Linn Gernert
Christopher Lawrence Cioffi
Robert Jason Herr
Nathan Bryan Mantlo
De La Nava Eva Maria Martin
Ana Isabel Mateo-Herranz
Daniel Ray Mayhugh
Xiaodong Wang
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of CY1110537T1 publication Critical patent/CY1110537T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Abstract

Αποκαλύπτονται ενώσεις τύπου I στον οποίο τα n, m, p, q, Υ, R1, R2, R3, R4, R5 και R6 είναι όπως ορίζονται εδώ και οι φαρμακευτικές συνθέσεις και μέθοδοι χρήσεως ως χρήσιμες για την αγωγή της αθηροσκληρώσεως και των συνεπειών της.
CY20091101151T 2003-10-08 2009-11-05 Ενωσεις και μεθοδοι για την αγωγη της δυσλιπιδαιμιας CY1110537T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50973603P 2003-10-08 2003-10-08
EP04793889A EP1670768B1 (en) 2003-10-08 2004-10-07 Compounds and methods for treating dyslipidemia

Publications (1)

Publication Number Publication Date
CY1110537T1 true CY1110537T1 (el) 2015-04-29

Family

ID=34465112

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091101151T CY1110537T1 (el) 2003-10-08 2009-11-05 Ενωσεις και μεθοδοι για την αγωγη της δυσλιπιδαιμιας

Country Status (25)

Country Link
US (1) US7749992B2 (el)
EP (2) EP1670768B1 (el)
JP (1) JP4773969B2 (el)
KR (1) KR20060085675A (el)
CN (1) CN1863778A (el)
AT (1) ATE442358T1 (el)
AU (1) AU2004282101A1 (el)
BR (1) BRPI0414186A (el)
CA (1) CA2537942A1 (el)
CY (1) CY1110537T1 (el)
DE (1) DE602004023100D1 (el)
DK (1) DK1670768T3 (el)
EA (1) EA200600737A1 (el)
EC (1) ECSP066484A (el)
ES (1) ES2332051T3 (el)
HR (1) HRP20090581T1 (el)
IL (1) IL173819A0 (el)
MA (1) MA28268A1 (el)
MX (1) MXPA06003927A (el)
NO (1) NO20062074L (el)
PL (1) PL1670768T3 (el)
PT (1) PT1670768E (el)
SI (1) SI1670768T1 (el)
WO (1) WO2005037796A1 (el)
ZA (1) ZA200602888B (el)

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CN103833636B (zh) * 2014-03-31 2015-09-02 武汉武药制药有限公司 一种莫扎伐普坦中间体的合成方法
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CN110291383B (zh) * 2017-02-23 2021-12-28 株式会社Ihi Oh自由基检测探测器、oh自由基测定装置以及oh自由基测定方法
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JP2023521460A (ja) 2020-04-15 2023-05-24 ビーブ、ヘルスケア、ユーケー、（ナンバー５）、リミテッド ヒト免疫不全ウイルス複製の阻害剤
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Also Published As

Publication number Publication date
NO20062074L (no) 2006-05-08
ECSP066484A (es) 2006-10-10
CN1863778A (zh) 2006-11-15
DE602004023100D1 (de) 2009-10-22
US7749992B2 (en) 2010-07-06
ES2332051T3 (es) 2010-01-25
PL1670768T3 (pl) 2010-01-29
KR20060085675A (ko) 2006-07-27
MA28268A1 (fr) 2006-11-01
BRPI0414186A (pt) 2006-10-31
MXPA06003927A (es) 2008-02-07
ZA200602888B (en) 2007-11-28
HRP20090581T1 (hr) 2009-12-31
ATE442358T1 (de) 2009-09-15
WO2005037796A1 (en) 2005-04-28
EA200600737A1 (ru) 2006-10-27
DK1670768T3 (da) 2009-11-09
CA2537942A1 (en) 2005-04-28
SI1670768T1 (sl) 2010-01-29
JP2007508301A (ja) 2007-04-05
AU2004282101A1 (en) 2005-04-28
IL173819A0 (en) 2006-07-05
EP2098512A1 (en) 2009-09-09
EP1670768A1 (en) 2006-06-21
JP4773969B2 (ja) 2011-09-14
US20070254869A1 (en) 2007-11-01
EP1670768B1 (en) 2009-09-09
PT1670768E (pt) 2009-11-20

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