CY1108495T1 - Μη στεροειδεις ρυθμιστες υποδοχεων προγεστερονης - Google Patents
Μη στεροειδεις ρυθμιστες υποδοχεων προγεστερονηςInfo
- Publication number
- CY1108495T1 CY1108495T1 CY20081101280T CY081101280T CY1108495T1 CY 1108495 T1 CY1108495 T1 CY 1108495T1 CY 20081101280 T CY20081101280 T CY 20081101280T CY 081101280 T CY081101280 T CY 081101280T CY 1108495 T1 CY1108495 T1 CY 1108495T1
- Authority
- CY
- Cyprus
- Prior art keywords
- adjusters
- non steroid
- progesteron receptor
- prodrug
- progesteron
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Η παρούσα εφεύρεση παρέχει ενώσεις σύμφωνα με το γενικό τύπο (Ι), ένα προφάρμακο τους, ένα φαρμακευτικά αποδεκτό άλας τους, ή ένα φαρμακευτικά αποδεκτό άλας ενός προφαρμάκου τους. Ειδικότερα, η παρούσα εφεύρεση παρέχει μη στερεοειδείς ενώσεις εξαιρετικής συγγένειας οι οποίες είναι αγωνιστές, μερικώς αγωμνιστές ή ανταγωνιστές του υποδοχέα προγεστερόνης.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02076350 | 2002-04-04 | ||
| EP03720570A EP1495030B1 (en) | 2002-04-04 | 2003-04-01 | Non-steroidal progesterone receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108495T1 true CY1108495T1 (el) | 2014-04-09 |
Family
ID=28685924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20081101280T CY1108495T1 (el) | 2002-04-04 | 2008-11-10 | Μη στεροειδεις ρυθμιστες υποδοχεων προγεστερονης |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7737136B2 (el) |
| EP (1) | EP1495030B1 (el) |
| JP (1) | JP4418683B2 (el) |
| KR (1) | KR100965173B1 (el) |
| CN (1) | CN1279044C (el) |
| AR (1) | AR039251A1 (el) |
| AT (1) | ATE404567T1 (el) |
| AU (1) | AU2003224161B2 (el) |
| BR (1) | BR0308890A (el) |
| CA (1) | CA2480940C (el) |
| CY (1) | CY1108495T1 (el) |
| DE (1) | DE60322867D1 (el) |
| DK (1) | DK1495030T3 (el) |
| EC (1) | ECSP045334A (el) |
| ES (1) | ES2310654T3 (el) |
| HK (1) | HK1070362A1 (el) |
| HR (1) | HRP20040913A2 (el) |
| IL (2) | IL164169A0 (el) |
| IS (1) | IS7452A (el) |
| MX (1) | MXPA04009709A (el) |
| NO (1) | NO20044473L (el) |
| NZ (1) | NZ535546A (el) |
| PE (1) | PE20040350A1 (el) |
| PL (1) | PL372846A1 (el) |
| PT (1) | PT1495030E (el) |
| RU (1) | RU2309155C2 (el) |
| SI (1) | SI1495030T1 (el) |
| TW (1) | TWI297685B (el) |
| WO (1) | WO2003084963A1 (el) |
| ZA (1) | ZA200407667B (el) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI297685B (en) | 2002-04-04 | 2008-06-11 | Organon Nv | Non-steroidal progesterone receptor modulators |
| TWI370129B (en) * | 2005-02-14 | 2012-08-11 | Msd Oss Bv | Non steroidal glucocorticoid receptor modulators |
| TWI375676B (en) * | 2005-08-29 | 2012-11-01 | Msd Oss Bv | Non-steroidal glucocorticoid receptor modulators |
| US7989442B2 (en) | 2006-09-27 | 2011-08-02 | N.V. Organon | Progesterone receptor modulators |
| CN101522689B (zh) * | 2006-09-27 | 2012-01-11 | 欧加农股份有限公司 | 吡啶并氧氮杂*孕酮受体调节剂 |
| TW200914029A (en) * | 2007-05-07 | 2009-04-01 | Organon Nv | New progesterone receptor modulators |
| US8063037B2 (en) | 2007-05-07 | 2011-11-22 | N. V. Organon | Progesterone receptor modulators |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4054572A (en) * | 1973-04-26 | 1977-10-18 | Akzona Incorporated | Hexahydro pyridine [1,2d] dibenza [b,f] (1,4)-diazepines |
| NL7305811A (el) | 1973-04-26 | 1974-10-29 | ||
| US4016161A (en) * | 1974-04-24 | 1977-04-05 | Akzona Incorporated | Amino-substituted 1,2,3,4,10,146-hexahydro-pyridino[1,2-a]dibenzo[c,f]azepines |
| DE19975054I2 (de) | 1987-08-08 | 2000-04-13 | Akzo Nobel Nv | Kontrazeptives Implantat |
| CA2026856A1 (en) | 1989-10-05 | 1991-04-06 | Mark G. Bock | 3-substituted-1,4-benzodiazepines useful as oxytocin |
| US5688810A (en) | 1994-12-22 | 1997-11-18 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
| TW358031B (en) | 1997-04-11 | 1999-05-11 | Akze Nobel N V | Drug delivery system for 2 or more active substances |
| TWI297685B (en) | 2002-04-04 | 2008-06-11 | Organon Nv | Non-steroidal progesterone receptor modulators |
| TWI370129B (en) | 2005-02-14 | 2012-08-11 | Msd Oss Bv | Non steroidal glucocorticoid receptor modulators |
| CN101522689B (zh) | 2006-09-27 | 2012-01-11 | 欧加农股份有限公司 | 吡啶并氧氮杂*孕酮受体调节剂 |
-
2003
- 2003-03-31 TW TW092107288A patent/TWI297685B/zh not_active IP Right Cessation
- 2003-04-01 CN CNB038099047A patent/CN1279044C/zh not_active Expired - Fee Related
- 2003-04-01 KR KR1020047015753A patent/KR100965173B1/ko not_active IP Right Cessation
- 2003-04-01 BR BR0308890-1A patent/BR0308890A/pt not_active IP Right Cessation
- 2003-04-01 SI SI200331416T patent/SI1495030T1/sl unknown
- 2003-04-01 US US10/510,275 patent/US7737136B2/en active Active
- 2003-04-01 ES ES03720570T patent/ES2310654T3/es not_active Expired - Lifetime
- 2003-04-01 PL PL03372846A patent/PL372846A1/xx not_active Application Discontinuation
- 2003-04-01 WO PCT/EP2003/050085 patent/WO2003084963A1/en active IP Right Grant
- 2003-04-01 AU AU2003224161A patent/AU2003224161B2/en not_active Ceased
- 2003-04-01 RU RU2004132215/04A patent/RU2309155C2/ru not_active IP Right Cessation
- 2003-04-01 DK DK03720570T patent/DK1495030T3/da active
- 2003-04-01 NZ NZ535546A patent/NZ535546A/en not_active IP Right Cessation
- 2003-04-01 AT AT03720570T patent/ATE404567T1/de active
- 2003-04-01 EP EP03720570A patent/EP1495030B1/en not_active Expired - Lifetime
- 2003-04-01 PT PT03720570T patent/PT1495030E/pt unknown
- 2003-04-01 MX MXPA04009709A patent/MXPA04009709A/es active IP Right Grant
- 2003-04-01 DE DE60322867T patent/DE60322867D1/de not_active Expired - Lifetime
- 2003-04-01 IL IL16416903A patent/IL164169A0/xx unknown
- 2003-04-01 CA CA2480940A patent/CA2480940C/en not_active Expired - Fee Related
- 2003-04-01 JP JP2003582160A patent/JP4418683B2/ja not_active Expired - Fee Related
- 2003-04-03 PE PE2003000343A patent/PE20040350A1/es not_active Application Discontinuation
- 2003-04-04 AR ARP030101176A patent/AR039251A1/es unknown
-
2004
- 2004-09-16 IS IS7452A patent/IS7452A/is unknown
- 2004-09-21 IL IL164169A patent/IL164169A/en not_active IP Right Cessation
- 2004-09-22 ZA ZA200407667A patent/ZA200407667B/en unknown
- 2004-10-01 EC EC2004005334A patent/ECSP045334A/es unknown
- 2004-10-04 HR HR20040913A patent/HRP20040913A2/xx not_active Application Discontinuation
- 2004-10-20 NO NO20044473A patent/NO20044473L/no not_active Application Discontinuation
-
2005
- 2005-04-11 HK HK05103033A patent/HK1070362A1/xx not_active IP Right Cessation
-
2008
- 2008-11-10 CY CY20081101280T patent/CY1108495T1/el unknown
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