CY1106409T1 - Παραγωγα κινολινης - Google Patents

Παραγωγα κινολινης

Info

Publication number
CY1106409T1
CY1106409T1 CY20071100405T CY071100405T CY1106409T1 CY 1106409 T1 CY1106409 T1 CY 1106409T1 CY 20071100405 T CY20071100405 T CY 20071100405T CY 071100405 T CY071100405 T CY 071100405T CY 1106409 T1 CY1106409 T1 CY 1106409T1
Authority
CY
Cyprus
Prior art keywords
quinoline derivatives
myopia
glaucoma
quinoline
treatment
Prior art date
Application number
CY20071100405T
Other languages
English (en)
Inventor
Peter Gull
Esteban Pombo Villar
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1106409T1 publication Critical patent/CY1106409T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Abstract

Η παρούσα εφεύρεση αφορά καινοτόμα παράγωγα βενζο [g] κινολίνης, για χρήση στη θεραπεία του γλαυκώματος και της μυωπίας.
CY20071100405T 2002-03-07 2007-03-22 Παραγωγα κινολινης CY1106409T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP02005117 2002-03-07
EP02005115 2002-03-07
EP03714784A EP1480970B1 (en) 2002-03-07 2003-03-06 Quinoline derivatives
PCT/EP2003/002321 WO2003074511A1 (en) 2002-03-07 2003-03-06 Quinoline derivatives

Publications (1)

Publication Number Publication Date
CY1106409T1 true CY1106409T1 (el) 2011-10-12

Family

ID=27790094

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100405T CY1106409T1 (el) 2002-03-07 2007-03-22 Παραγωγα κινολινης

Country Status (29)

Country Link
US (2) US7399768B2 (el)
EP (1) EP1480970B1 (el)
JP (2) JP2005519117A (el)
KR (1) KR101027977B1 (el)
CN (2) CN1939915A (el)
AR (1) AR038730A1 (el)
AU (1) AU2003219023B2 (el)
BR (1) BR0308201A (el)
CA (2) CA2477720C (el)
CO (1) CO5611196A2 (el)
CY (1) CY1106409T1 (el)
DE (1) DE60311233T2 (el)
DK (1) DK1480970T3 (el)
EC (1) ECSP045271A (el)
EG (1) EG24415A (el)
ES (1) ES2279100T3 (el)
HK (1) HK1071364A1 (el)
IL (1) IL163769A0 (el)
MX (1) MXPA04008666A (el)
MY (1) MY134325A (el)
NO (1) NO20044117L (el)
NZ (1) NZ534732A (el)
PE (1) PE20030927A1 (el)
PL (2) PL215012B1 (el)
PT (1) PT1480970E (el)
RU (1) RU2345991C2 (el)
SI (1) SI1480970T1 (el)
TW (1) TW200406401A (el)
WO (1) WO2003074511A1 (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1757601B1 (en) * 2002-03-07 2009-08-05 Novartis AG Quinoline derivatives and their use in glaucoma and myopia
US10729710B2 (en) 2017-11-24 2020-08-04 H. Lundbeck A/S Catecholamine prodrugs for use in the treatment of Parkinson's disease
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100555A (en) * 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
GB9326010D0 (en) * 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
TW378209B (en) * 1996-07-08 2000-01-01 Novartis Ag Benzo[g]quinoline derivatives, their preparation and the pharmaceutical composition containing them
PE20030240A1 (es) * 2001-07-09 2003-04-16 Novartis Ag DERIVADOS DE BENZO [g] QUINOLINA

Also Published As

Publication number Publication date
SI1480970T1 (sl) 2007-06-30
PL210336B1 (pl) 2012-01-31
PE20030927A1 (es) 2003-12-26
KR101027977B1 (ko) 2011-04-13
RU2004129767A (ru) 2005-06-27
DE60311233T2 (de) 2007-11-15
BR0308201A (pt) 2005-01-04
PL215012B1 (pl) 2013-10-31
CO5611196A2 (es) 2006-02-28
MXPA04008666A (es) 2004-12-06
EP1480970B1 (en) 2007-01-17
CA2477720C (en) 2010-09-21
EP1480970A1 (en) 2004-12-01
CN1939915A (zh) 2007-04-04
JP2005519117A (ja) 2005-06-30
WO2003074511A1 (en) 2003-09-12
PL394208A1 (pl) 2011-08-16
CA2706618A1 (en) 2003-09-12
TW200406401A (en) 2004-05-01
PL370915A1 (en) 2005-06-13
IL163769A0 (en) 2005-12-18
CN1639148A (zh) 2005-07-13
PT1480970E (pt) 2007-03-30
AU2003219023A1 (en) 2003-09-16
US20080255176A1 (en) 2008-10-16
NO20044117L (no) 2004-09-28
NZ534732A (en) 2006-05-26
DE60311233D1 (de) 2007-03-08
JP2010095550A (ja) 2010-04-30
AU2003219023B2 (en) 2006-11-30
KR20040089615A (ko) 2004-10-21
US7399768B2 (en) 2008-07-15
RU2345991C2 (ru) 2009-02-10
EG24415A (en) 2009-05-25
HK1071364A1 (en) 2005-07-15
DK1480970T3 (da) 2007-03-05
US20050234085A1 (en) 2005-10-20
CA2477720A1 (en) 2003-09-12
CN1293070C (zh) 2007-01-03
ES2279100T3 (es) 2007-08-16
MY134325A (en) 2007-12-31
AR038730A1 (es) 2005-01-26
ECSP045271A (es) 2004-10-26

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