CY1105548T1 - Συνδυασμος του loteprednol και αγωνιστων του β2-αδρενοϋποδοχεως και η χρηση του με εισπνοες για την αγωγη του βρογχικου ασθματος - Google Patents
Συνδυασμος του loteprednol και αγωνιστων του β2-αδρενοϋποδοχεως και η χρηση του με εισπνοες για την αγωγη του βρογχικου ασθματοςInfo
- Publication number
- CY1105548T1 CY1105548T1 CY20051101559T CY051101559T CY1105548T1 CY 1105548 T1 CY1105548 T1 CY 1105548T1 CY 20051101559 T CY20051101559 T CY 20051101559T CY 051101559 T CY051101559 T CY 051101559T CY 1105548 T1 CY1105548 T1 CY 1105548T1
- Authority
- CY
- Cyprus
- Prior art keywords
- combination
- loteprednol
- treatment
- inhals
- bronchial asthma
- Prior art date
Links
- YPZVAYHNBBHPTO-MXRBDKCISA-N loteprednol Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)OCCl)[C@@H]4[C@@H]3CCC2=C1 YPZVAYHNBBHPTO-MXRBDKCISA-N 0.000 title abstract 2
- 229960001798 loteprednol Drugs 0.000 title abstract 2
- 208000006673 asthma Diseases 0.000 title 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 title 1
- 229940079593 drug Drugs 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 206010020751 Hypersensitivity Diseases 0.000 abstract 2
- 230000007815 allergy Effects 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 210000002345 respiratory system Anatomy 0.000 abstract 2
- 239000000048 adrenergic agonist Substances 0.000 abstract 1
- 102000014974 beta2-adrenergic receptor activity proteins Human genes 0.000 abstract 1
- 108040006828 beta2-adrenergic receptor activity proteins Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Abstract
Η εφεύρεση αφορά σε έναν νέο συνδυασμό ενός μαλακού στεροειδούς, ιδιαίτερα του Loteprednol και τουλάχιστον ενός αγωνιστού β2-αδρενοϋποδοχέως για την ταυτόχρονη, διαδοχική ή χωριστή αγωγή αλλεργιών και/ή παθήσεων της αναπνευστικής οδού, σε φάρμακα που περιέχουν τον συνδυασμό, σε μέθοδο για την παρασκευή τέτοιων φαρμάκων και στην χρησιμοποίηση του νέου συνδυασμού για την παρασκευή φαρμάκων για την ταυτόχρονη, διαδοχική ή χωριστή αγωγή αλλεργιών και/ή παθήσεων της αναπνευστικής οδού.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19947235A DE19947235A1 (de) | 1999-09-30 | 1999-09-30 | Neue Kombination von Loteprednol und beta¶2¶-Adrenorezeptor-Agonisten |
PCT/EP2000/009392 WO2001022956A2 (de) | 1999-09-30 | 2000-09-26 | NEUE KOMBINATION VON LOTEPREDNOL UND β2-ADRENOZEPTOR-AGONISTEN |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1105548T1 true CY1105548T1 (el) | 2010-07-28 |
Family
ID=7924101
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20051101559T CY1105548T1 (el) | 1999-09-30 | 2005-12-15 | Συνδυασμος του loteprednol και αγωνιστων του β2-αδρενοϋποδοχεως και η χρηση του με εισπνοες για την αγωγη του βρογχικου ασθματος |
Country Status (20)
Country | Link |
---|---|
US (1) | US7521438B1 (el) |
EP (1) | EP1216047B1 (el) |
JP (1) | JP5068912B2 (el) |
AR (1) | AR025924A1 (el) |
AT (1) | ATE306271T1 (el) |
AU (1) | AU7907400A (el) |
BR (1) | BR0014374B1 (el) |
CA (1) | CA2389111C (el) |
CY (1) | CY1105548T1 (el) |
CZ (1) | CZ296396B6 (el) |
DE (2) | DE19947235A1 (el) |
DK (1) | DK1216047T3 (el) |
EE (1) | EE05050B1 (el) |
ES (1) | ES2248131T3 (el) |
HU (1) | HUP0202753A3 (el) |
MX (1) | MXPA02003329A (el) |
PL (1) | PL196729B1 (el) |
SI (1) | SI1216047T1 (el) |
TW (1) | TWI253930B (el) |
WO (1) | WO2001022956A2 (el) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0012260D0 (en) * | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel composition |
US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
CN100450488C (zh) * | 2003-11-03 | 2009-01-14 | 诺顿·希尔思凯尔有限公司 | 用于干粉吸入剂的软类固醇组合物 |
EP2221048A1 (en) * | 2009-02-18 | 2010-08-25 | Siegfried Generics International AG | Pharmaceutical composition for inhalation |
US9238144B2 (en) * | 2013-03-14 | 2016-01-19 | Neuropace, Inc. | Optimizing data retrieval from an active implantable medical device |
WO2022016150A1 (en) * | 2020-07-17 | 2022-01-20 | Ross Peter M | Methods for the treatment of cytokine release syndromes |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB416950A (en) * | 1933-07-28 | 1934-09-25 | Ambrose Heal | An improved support member for beds, settees, wardrobes and other articles of furniture |
US4996335A (en) | 1980-07-10 | 1991-02-26 | Nicholas S. Bodor | Soft steroids having anti-inflammatory activity |
US4710495A (en) | 1980-07-10 | 1987-12-01 | Otsuka Pharmaceutical Co., Ltd. | Soft steroids having anti-inflammatory activity |
ZA814440B (en) * | 1980-07-10 | 1982-10-27 | Otsuka Pharma Co Ltd | Soft steroids having anti-inflammatory activity |
TW503113B (en) * | 1997-01-16 | 2002-09-21 | Senju Pharma Co | Aqueous suspension for nasal administration |
JP2001511160A (ja) * | 1997-02-05 | 2001-08-07 | ヤゴ リサーチ アクチェンゲゼルシャフト | 医学用エアゾール配合物 |
US5830490A (en) * | 1997-04-04 | 1998-11-03 | Weinstein; Robert E. | Method and device for organizing and coordinating the combined use of topical aerosols and oral medications for the treatment of disorders |
PT1131059E (pt) | 1998-11-13 | 2003-07-31 | Jago Res Ag | Po seco para inalacao |
-
1999
- 1999-09-30 DE DE19947235A patent/DE19947235A1/de not_active Withdrawn
-
2000
- 2000-09-26 TW TW089119863A patent/TWI253930B/zh not_active IP Right Cessation
- 2000-09-26 HU HU0202753A patent/HUP0202753A3/hu unknown
- 2000-09-26 DE DE50011340T patent/DE50011340D1/de not_active Expired - Lifetime
- 2000-09-26 ES ES00969304T patent/ES2248131T3/es not_active Expired - Lifetime
- 2000-09-26 AT AT00969304T patent/ATE306271T1/de active
- 2000-09-26 DK DK00969304T patent/DK1216047T3/da active
- 2000-09-26 AU AU79074/00A patent/AU7907400A/en not_active Abandoned
- 2000-09-26 US US10/089,449 patent/US7521438B1/en not_active Expired - Fee Related
- 2000-09-26 JP JP2001526168A patent/JP5068912B2/ja not_active Expired - Fee Related
- 2000-09-26 SI SI200030769T patent/SI1216047T1/sl unknown
- 2000-09-26 CZ CZ20021095A patent/CZ296396B6/cs not_active IP Right Cessation
- 2000-09-26 EE EEP200200163A patent/EE05050B1/xx not_active IP Right Cessation
- 2000-09-26 PL PL353487A patent/PL196729B1/pl not_active IP Right Cessation
- 2000-09-26 WO PCT/EP2000/009392 patent/WO2001022956A2/de active IP Right Grant
- 2000-09-26 CA CA002389111A patent/CA2389111C/en not_active Expired - Lifetime
- 2000-09-26 MX MXPA02003329A patent/MXPA02003329A/es active IP Right Grant
- 2000-09-26 BR BRPI0014374-0A patent/BR0014374B1/pt not_active IP Right Cessation
- 2000-09-26 EP EP00969304A patent/EP1216047B1/de not_active Expired - Lifetime
- 2000-09-29 AR ARP000105167A patent/AR025924A1/es not_active Application Discontinuation
-
2005
- 2005-12-15 CY CY20051101559T patent/CY1105548T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PL353487A1 (en) | 2003-11-17 |
BR0014374B1 (pt) | 2012-12-25 |
DK1216047T3 (da) | 2006-02-13 |
HUP0202753A2 (hu) | 2002-12-28 |
JP5068912B2 (ja) | 2012-11-07 |
CZ20021095A3 (cs) | 2002-08-14 |
MXPA02003329A (es) | 2004-09-10 |
BR0014374A (pt) | 2002-06-25 |
AR025924A1 (es) | 2002-12-18 |
EE05050B1 (et) | 2008-08-15 |
CA2389111C (en) | 2009-04-14 |
HUP0202753A3 (en) | 2004-06-28 |
EP1216047A2 (de) | 2002-06-26 |
EP1216047B1 (de) | 2005-10-12 |
EE200200163A (et) | 2003-04-15 |
CZ296396B6 (cs) | 2006-03-15 |
JP2003510276A (ja) | 2003-03-18 |
WO2001022956A2 (de) | 2001-04-05 |
DE50011340D1 (de) | 2006-02-23 |
TWI253930B (en) | 2006-05-01 |
PL196729B1 (pl) | 2008-01-31 |
AU7907400A (en) | 2001-04-30 |
WO2001022956A3 (de) | 2001-10-11 |
SI1216047T1 (sl) | 2006-02-28 |
US7521438B1 (en) | 2009-04-21 |
CA2389111A1 (en) | 2001-04-05 |
ATE306271T1 (de) | 2005-10-15 |
ES2248131T3 (es) | 2006-03-16 |
DE19947235A1 (de) | 2001-04-05 |
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