CU20120063A7 - A METHOD FOR OBTAINING REPROGRAMED DAILY CELLS - Google Patents
A METHOD FOR OBTAINING REPROGRAMED DAILY CELLSInfo
- Publication number
- CU20120063A7 CU20120063A7 CU2012000063A CU20120063A CU20120063A7 CU 20120063 A7 CU20120063 A7 CU 20120063A7 CU 2012000063 A CU2012000063 A CU 2012000063A CU 20120063 A CU20120063 A CU 20120063A CU 20120063 A7 CU20120063 A7 CU 20120063A7
- Authority
- CU
- Cuba
- Prior art keywords
- cells
- patient
- obtaining
- compromised
- transdifferentiated
- Prior art date
Links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
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- A—HUMAN NECESSITIES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
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- A—HUMAN NECESSITIES
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Gynecology & Obstetrics (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
Abstract
La presente invención se refiere a un método para la obtención de células dianas reprogramadas que pueden ser útiles para tratar diversas enfermedades, trastornos o afecciones en un paciente, mediante la utilización de células reprogramadas, como por ejemplo células retrodiferenciadas, transdiferenciadas o rediferenciadas. El método comprende obtener células comprometidas del paciente, retrodiferenciar las células comprometidas para obtener células diana retrodiferenciadas, y administrar las células retrodiferenciadas al paciente. En determinadas realizaciones, el método comprende obtener células comprometidas del paciente, transdiferenciar las células comprometidas para obtener células diana transdiferenciadas, y administrar las células diana transdiferenciadas al paciente. Las células diana retrodiferenciadas o transdiferenciadas reparan o reponen los tejidos o células en el paciente.The present invention relates to a method for obtaining reprogrammed target cells that can be useful for treating various diseases, disorders or conditions in a patient, by using reprogrammed cells, such as, for example, backdifferentiated, transdifferentiated or redifferentiated cells. The method comprises obtaining compromised cells from the patient, retrodifferentiating the compromised cells to obtain retrodifferentiated target cells, and administering the retrodifferentiated cells to the patient. In certain embodiments, the method comprises obtaining compromised cells from the patient, transdifferentiating the compromised cells to obtain transdifferentiated target cells, and administering the transdifferentiated target cells to the patient. Retrodifferentiated or transdifferentiated target cells repair or replenish tissues or cells in the patient.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/GB2009/051396 WO2011048350A1 (en) | 2009-10-19 | 2009-10-19 | Treatment using reprogrammed mature adult cells |
Publications (2)
Publication Number | Publication Date |
---|---|
CU20120063A7 true CU20120063A7 (en) | 2012-10-15 |
CU24006B1 CU24006B1 (en) | 2014-06-27 |
Family
ID=42199514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU2012000063A CU24006B1 (en) | 2009-10-19 | 2012-04-19 | A METHOD FOR OBTAINING REPROGRAMED DAILY CELLS |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP2490702A1 (en) |
JP (1) | JP6073135B2 (en) |
KR (1) | KR101766203B1 (en) |
CN (1) | CN102647989A (en) |
AU (1) | AU2009354350B2 (en) |
CA (1) | CA2781522A1 (en) |
CH (1) | CH704227B1 (en) |
CU (1) | CU24006B1 (en) |
IL (1) | IL218902A (en) |
MA (1) | MA33740B1 (en) |
MX (1) | MX2012004522A (en) |
RU (1) | RU2635317C2 (en) |
TN (1) | TN2012000157A1 (en) |
UA (1) | UA109265C2 (en) |
WO (1) | WO2011048350A1 (en) |
ZA (1) | ZA201202664B (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20170296595A1 (en) * | 2014-09-18 | 2017-10-19 | North Carolina State University | Mammalian Lung Spheroids and Lung Spheroid Cells and Uses Thereof |
JP6113133B2 (en) | 2014-11-06 | 2017-04-12 | 日本メナード化粧品株式会社 | Stem cell undifferentiated state maintenance agent and growth promoter |
IL300420B1 (en) | 2015-10-16 | 2024-05-01 | Univ Columbia | Compositions and methods for inhibition of lineage specific antigens |
CN107114355A (en) * | 2016-08-01 | 2017-09-01 | 北京世纪劲得生物技术有限公司 | A kind of fat cell protection liquid and preparation method thereof |
CN110662554A (en) * | 2017-02-28 | 2020-01-07 | Vor生物制药股份有限公司 | Compositions and methods for inhibiting lineage specific proteins |
CN109731012A (en) * | 2017-10-30 | 2019-05-10 | 邹兆中 | It improves biological immune and treats the active method of active principle |
CN109706119B (en) * | 2018-04-13 | 2020-11-27 | 诺未科技(北京)有限公司 | Culture system and method for expanding hematopoietic stem cells and application thereof |
SG11202101994XA (en) | 2018-08-28 | 2021-03-30 | Vor Biopharma Inc | Genetically engineered hematopoietic stem cells and uses thereof |
KR20200025210A (en) * | 2018-08-29 | 2020-03-10 | 주식회사 스템모어 | Composition for culturing dermal papilla cells and the method for culturing dermal papilla cells using the same |
WO2021240204A1 (en) * | 2020-05-23 | 2021-12-02 | Pakravan Nafiseh | Sperm head for resolution of inflammation, tissue repair & regeneration, and restoration of tissue function: new approach of cell therapy |
CN114231481B (en) * | 2021-12-21 | 2023-07-18 | 中国人民解放军总医院 | Chemical induction method for taking reprogramming Cheng Zhenpi fibroblast as endothelial progenitor cell |
WO2023217126A1 (en) * | 2022-05-10 | 2023-11-16 | 上海赛立维生物科技有限公司 | Renal epithelial precursor-like cell, and preparation method therefor, preparation thereof and use thereof |
WO2024050517A1 (en) * | 2022-09-02 | 2024-03-07 | The University Of North Carolina At Chapel Hill | Methods of making and using anticancer reprogrammed b cells |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5554512A (en) * | 1993-05-24 | 1996-09-10 | Immunex Corporation | Ligands for flt3 receptors |
US7112440B2 (en) * | 1995-02-02 | 2006-09-26 | Ghazi Jaswinder Dhoot | Method of increasing the relative number of CD45 low cells in a cell population |
US9068164B1 (en) * | 1995-02-02 | 2015-06-30 | Tristem Trading (Cyprus) Limited | Method of preparing an undifferentiated cell |
GB9502022D0 (en) * | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
WO1996035224A1 (en) * | 1995-05-02 | 1996-11-07 | Philips Electronics N.V. | Colour cathode ray tube |
US20050037490A1 (en) * | 1999-10-29 | 2005-02-17 | Lawrence Rosenberg | Medium for preparing dedifferentiated cells |
TWI288779B (en) * | 2002-03-28 | 2007-10-21 | Blasticon Biotech Forschung | Dedifferentiated, programmable stem cells of monocytic origin, and their production and use |
WO2006014642A1 (en) * | 2004-07-22 | 2006-02-09 | Five Prime Therapeutics, Inc. | Method of producing autologous embryonic stem cells |
KR20110134939A (en) * | 2009-04-03 | 2011-12-15 | 더 맥클린 하스피털 코퍼레이션 | Induced pluripotent stem cells |
-
2009
- 2009-10-19 CN CN2009801630439A patent/CN102647989A/en active Pending
- 2009-10-19 AU AU2009354350A patent/AU2009354350B2/en not_active Ceased
- 2009-10-19 UA UAA201205968A patent/UA109265C2/en unknown
- 2009-10-19 EP EP09736651A patent/EP2490702A1/en not_active Withdrawn
- 2009-10-19 MX MX2012004522A patent/MX2012004522A/en unknown
- 2009-10-19 RU RU2012120713A patent/RU2635317C2/en not_active IP Right Cessation
- 2009-10-19 JP JP2012534757A patent/JP6073135B2/en not_active Expired - Fee Related
- 2009-10-19 CA CA2781522A patent/CA2781522A1/en not_active Abandoned
- 2009-10-19 KR KR1020127012911A patent/KR101766203B1/en active IP Right Grant
- 2009-10-19 WO PCT/GB2009/051396 patent/WO2011048350A1/en active Application Filing
- 2009-10-19 CH CH00524/12A patent/CH704227B1/en not_active IP Right Cessation
-
2012
- 2012-03-28 IL IL218902A patent/IL218902A/en not_active IP Right Cessation
- 2012-04-04 TN TNP2012000157A patent/TN2012000157A1/en unknown
- 2012-04-12 ZA ZA2012/02664A patent/ZA201202664B/en unknown
- 2012-04-19 CU CU2012000063A patent/CU24006B1/en active IP Right Grant
- 2012-05-11 MA MA34857A patent/MA33740B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP6073135B2 (en) | 2017-02-01 |
EP2490702A1 (en) | 2012-08-29 |
IL218902A0 (en) | 2012-06-28 |
RU2635317C2 (en) | 2017-11-10 |
KR101766203B1 (en) | 2017-08-08 |
TN2012000157A1 (en) | 2013-12-12 |
AU2009354350B2 (en) | 2015-09-03 |
RU2012120713A (en) | 2013-11-27 |
AU2009354350A1 (en) | 2012-04-19 |
CH704227B1 (en) | 2015-05-15 |
KR20120099686A (en) | 2012-09-11 |
CN102647989A (en) | 2012-08-22 |
UA109265C2 (en) | 2015-08-10 |
WO2011048350A1 (en) | 2011-04-28 |
CA2781522A1 (en) | 2011-04-28 |
JP2013508343A (en) | 2013-03-07 |
IL218902A (en) | 2017-06-29 |
MX2012004522A (en) | 2012-05-08 |
CU24006B1 (en) | 2014-06-27 |
MA33740B1 (en) | 2012-11-01 |
ZA201202664B (en) | 2013-02-27 |
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