CS83892A3 - Novel amides of carboxylic acids, process of their preparation andpharmaceutical compositions based thereon - Google Patents
Novel amides of carboxylic acids, process of their preparation andpharmaceutical compositions based thereon Download PDFInfo
- Publication number
- CS83892A3 CS83892A3 CS92838A CS83892A CS83892A3 CS 83892 A3 CS83892 A3 CS 83892A3 CS 92838 A CS92838 A CS 92838A CS 83892 A CS83892 A CS 83892A CS 83892 A3 CS83892 A3 CS 83892A3
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- tetrahydro
- oxo
- benzoic acid
- trimethyl
- ethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH86391 | 1991-03-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS83892A3 true CS83892A3 (en) | 1992-10-14 |
Family
ID=4196940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS92838A CS83892A3 (en) | 1991-03-21 | 1992-03-19 | Novel amides of carboxylic acids, process of their preparation andpharmaceutical compositions based thereon |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5216148A (es) |
| EP (1) | EP0504695A1 (es) |
| JP (1) | JPH07165709A (es) |
| KR (1) | KR920018029A (es) |
| AU (1) | AU649308B2 (es) |
| BR (1) | BR9200951A (es) |
| CA (1) | CA2061662A1 (es) |
| CS (1) | CS83892A3 (es) |
| FI (1) | FI921135A (es) |
| HU (1) | HUT60465A (es) |
| IE (1) | IE920907A1 (es) |
| IL (1) | IL101242A (es) |
| IS (1) | IS3823A (es) |
| MX (1) | MX9201143A (es) |
| MY (1) | MY131268A (es) |
| NO (1) | NO921105L (es) |
| NZ (1) | NZ241953A (es) |
| TW (1) | TW221425B (es) |
| UY (1) | UY23386A1 (es) |
| YU (1) | YU24792A (es) |
| ZA (1) | ZA921889B (es) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599548A (en) * | 1995-05-08 | 1997-02-04 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides and retinol or retinyl ester |
| ZA9610853B (en) * | 1995-12-29 | 1998-04-06 | Smithkline Beecham Corp | Processes and intermediates for preparing pharmaceuticals. |
| US5693330A (en) * | 1996-04-25 | 1997-12-02 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing melinamide and a retinoid |
| US5716627A (en) * | 1996-04-25 | 1998-02-10 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester |
| US5747051A (en) * | 1996-09-27 | 1998-05-05 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an amide of a hydroxy fatty acid and a retinoid |
| US5955092A (en) * | 1996-09-27 | 1999-09-21 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an n-substituted fatty acid amide and retinol or retinyl ester |
| US7572788B2 (en) * | 1999-04-30 | 2009-08-11 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| US20060025388A1 (en) | 1999-04-30 | 2006-02-02 | Glick Gary D | Compositions and methods relating to novel compounds and targets thereof |
| US20040176358A1 (en) * | 1999-04-30 | 2004-09-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| DE60007960T2 (de) * | 1999-04-30 | 2004-10-21 | Univ Michigan Ann Arbor | Therapeutische Anwendungen von pro-apoptotischen Benzodiazepinen |
| US20050113460A1 (en) * | 1999-04-30 | 2005-05-26 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| WO2001035964A1 (en) * | 1999-11-18 | 2001-05-25 | Antexpharma, Inc. | Substituted 1-benzazepines and derivatives thereof |
| TW200508197A (en) * | 2003-03-31 | 2005-03-01 | Ucb Sa | Indolone-acetamide derivatives, processes for preparing them and their uses |
| US20050202055A1 (en) * | 2004-03-11 | 2005-09-15 | Koichi Shudo, Tokyo, Japan | Anti-wrinkle agent |
| US20050272723A1 (en) * | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
| US20060052369A1 (en) * | 2004-09-07 | 2006-03-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| JP2008528448A (ja) * | 2005-01-03 | 2008-07-31 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 新規化合物に関連する組成物および方法、ならびにその標的 |
| EP1893218A4 (en) | 2005-06-01 | 2011-01-12 | Univ Michigan | NON-SOLVATED BENZODIAZEPINE PREPARATIONS AND METHODS |
| US20070105844A1 (en) * | 2005-10-26 | 2007-05-10 | Regents Of The University Of Michigan | Therapeutic compositions and methods |
| EP1948191B1 (en) | 2005-11-01 | 2013-01-16 | The Regents of the University of Michigan | Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties |
| US7759338B2 (en) * | 2006-04-27 | 2010-07-20 | The Regents Of The University Of Michigan | Soluble 1,4 benzodiazepine compounds and stable salts thereof |
| EP2037741B1 (en) | 2006-06-09 | 2013-11-27 | The Regents Of The University Of Michigan | Benzodiazepine derivatives for use in the treatment of immune, inflammatory and proliferative disorders |
| CA2680017C (en) | 2007-03-09 | 2013-11-12 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| CA2698248C (en) | 2007-09-14 | 2017-08-29 | The Regents Of The University Of Michigan | Phenyl acyl guanidine derivatives as f1f0-atpase inhibitors and the use thereof |
| CA2703005A1 (en) | 2007-11-06 | 2009-05-14 | The Regents Of The University Of Michigan | Benzodiazepinone compounds useful in the treatment of skin conditions |
| PT2254873E (pt) | 2008-02-22 | 2014-08-29 | Otsuka Pharma Co Ltd | Compostos benzodiazepínicos e composições farmacêuticas que os contêm |
| US8497307B2 (en) | 2008-09-11 | 2013-07-30 | The Regents Of The University Of Michigan | Aryl guanidine F1F0-ATPase inhibitors and related methods |
| US8604023B2 (en) | 2009-04-17 | 2013-12-10 | The Regents Of The University Of Michigan | 1,4-benzodiazepinone compounds and their use in treating cancer |
| TWI481601B (zh) * | 2009-08-21 | 2015-04-21 | Otsuka Pharma Co Ltd | 含氮化合物及藥學組成物 |
| JP5649577B2 (ja) | 2009-08-21 | 2015-01-07 | 大塚製薬株式会社 | ベンゾ［ｂ］［１，４］ジアゼピン−２，４−ジオン化合物の製造方法 |
| EP2470020A4 (en) | 2009-09-18 | 2013-03-13 | Univ Michigan | BENZODIAZEPINONE COMPOUNDS AND TREATMENT METHODS THEREWITH |
| CA2780333C (en) | 2009-11-17 | 2016-05-24 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
| AU2010322287B2 (en) | 2009-11-17 | 2014-04-03 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
| AU2011245441B2 (en) | 2010-04-29 | 2014-12-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Activators of human pyruvate kinase |
| JP2012184225A (ja) * | 2011-02-18 | 2012-09-27 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3803775A1 (de) * | 1988-02-09 | 1989-08-17 | Boehringer Mannheim Gmbh | Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| DE3818830A1 (de) * | 1988-06-03 | 1989-12-14 | Boehringer Mannheim Gmbh | Bicyclische carboxamide, verfahren zu ihrer herstellung, deren vorstufen, und diese verbindungen enthaltende arzneimittel |
| AU626881B2 (en) * | 1988-07-14 | 1992-08-13 | F. Hoffmann-La Roche Ag | Benzofused heterocyclics used as pharmaceuticals |
-
1991
- 1991-03-19 BR BR929200951A patent/BR9200951A/pt not_active Application Discontinuation
-
1992
- 1992-02-20 TW TW081101237A patent/TW221425B/zh active
- 1992-02-20 AU AU11089/92A patent/AU649308B2/en not_active Ceased
- 1992-02-21 CA CA002061662A patent/CA2061662A1/en not_active Abandoned
- 1992-02-27 US US07/842,662 patent/US5216148A/en not_active Expired - Fee Related
- 1992-03-09 EP EP92103970A patent/EP0504695A1/de not_active Withdrawn
- 1992-03-12 YU YU24792A patent/YU24792A/sh unknown
- 1992-03-13 ZA ZA921889A patent/ZA921889B/xx unknown
- 1992-03-13 NZ NZ241953A patent/NZ241953A/en unknown
- 1992-03-16 HU HU9200871A patent/HUT60465A/hu unknown
- 1992-03-16 MX MX9201143A patent/MX9201143A/es not_active IP Right Cessation
- 1992-03-16 IL IL10124292A patent/IL101242A/en not_active IP Right Cessation
- 1992-03-17 JP JP4090152A patent/JPH07165709A/ja active Pending
- 1992-03-17 FI FI921135A patent/FI921135A/fi not_active Application Discontinuation
- 1992-03-19 CS CS92838A patent/CS83892A3/cs unknown
- 1992-03-19 MY MYPI92000458A patent/MY131268A/en unknown
- 1992-03-20 UY UY23386A patent/UY23386A1/es not_active IP Right Cessation
- 1992-03-20 IE IE090792A patent/IE920907A1/en unknown
- 1992-03-20 IS IS3823A patent/IS3823A/is unknown
- 1992-03-20 NO NO92921105A patent/NO921105L/no unknown
- 1992-03-20 KR KR1019920004612A patent/KR920018029A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0504695A1 (de) | 1992-09-23 |
| AU649308B2 (en) | 1994-05-19 |
| IL101242A0 (en) | 1992-11-15 |
| IL101242A (en) | 1995-12-08 |
| IE920907A1 (en) | 1992-09-23 |
| HU9200871D0 (en) | 1992-05-28 |
| UY23386A1 (es) | 1992-11-05 |
| FI921135A (fi) | 1992-09-22 |
| FI921135A0 (fi) | 1992-03-17 |
| HUT60465A (en) | 1992-09-28 |
| KR920018029A (ko) | 1992-10-21 |
| AU1108992A (en) | 1992-09-24 |
| JPH07165709A (ja) | 1995-06-27 |
| NZ241953A (en) | 1994-11-25 |
| TW221425B (es) | 1994-03-01 |
| IS3823A (is) | 1992-09-22 |
| NO921105L (no) | 1992-09-22 |
| ZA921889B (en) | 1992-11-25 |
| MY131268A (en) | 2007-07-31 |
| US5216148A (en) | 1993-06-01 |
| NO921105D0 (no) | 1992-03-20 |
| BR9200951A (pt) | 1992-11-17 |
| MX9201143A (es) | 1992-10-01 |
| CA2061662A1 (en) | 1992-09-22 |
| YU24792A (sh) | 1994-09-09 |
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