CS198295B2 - Method of producing water soluble corticoides - Google Patents

Method of producing water soluble corticoides Download PDF

Info

Publication number
CS198295B2
CS198295B2 CS782252A CS225278A CS198295B2 CS 198295 B2 CS198295 B2 CS 198295B2 CS 782252 A CS782252 A CS 782252A CS 225278 A CS225278 A CS 225278A CS 198295 B2 CS198295 B2 CS 198295B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
hydroxy
methyl
dioxo
alkali metal
Prior art date
Application number
CS782252A
Other languages
Czech (cs)
English (en)
Inventor
Ulrich Kerb
Rudolf Wiechart
Joachim-Friedrich Kapp
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of CS198295B2 publication Critical patent/CS198295B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
CS782252A 1977-04-06 1978-04-06 Method of producing water soluble corticoides CS198295B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772715853 DE2715853A1 (de) 1977-04-06 1977-04-06 Wasserloesliche kortikoide

Publications (1)

Publication Number Publication Date
CS198295B2 true CS198295B2 (en) 1980-05-30

Family

ID=6005979

Family Applications (1)

Application Number Title Priority Date Filing Date
CS782252A CS198295B2 (en) 1977-04-06 1978-04-06 Method of producing water soluble corticoides

Country Status (29)

Country Link
JP (1) JPS53149963A (sv)
AT (1) ATA239978A (sv)
AU (1) AU3481178A (sv)
BE (1) BE865760A (sv)
BG (1) BG28578A3 (sv)
CA (1) CA1113452A (sv)
CH (1) CH638537A5 (sv)
CS (1) CS198295B2 (sv)
DD (1) DD135082A5 (sv)
DE (1) DE2715853A1 (sv)
DK (1) DK153378A (sv)
EG (1) EG13249A (sv)
ES (1) ES468572A1 (sv)
FI (1) FI781053A (sv)
FR (1) FR2386557A1 (sv)
GB (1) GB1602266A (sv)
IE (1) IE46602B1 (sv)
IL (1) IL54443A0 (sv)
IT (1) IT1094296B (sv)
LU (1) LU79375A1 (sv)
NL (1) NL7803188A (sv)
NO (1) NO781200L (sv)
NZ (1) NZ186745A (sv)
PL (1) PL114096B1 (sv)
PT (1) PT67872B (sv)
RO (1) RO81076A2 (sv)
SE (1) SE7803837L (sv)
SU (1) SU668611A3 (sv)
ZA (1) ZA781977B (sv)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948533A (en) * 1984-03-28 1990-08-14 The Upjohn Company 11a-hydroxy steroid diester

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1169444B (de) * 1961-02-22 1964-05-06 Schering Ag Verfahren zur Herstellung von ?-16ª‡-Methylsteroiden
YU34304B (en) * 1968-08-17 1979-04-30 Schering Ag Process for preparing corticoid-21-mono-phosphates
DK290774A (sv) * 1973-06-08 1975-02-03 Schering Ag

Also Published As

Publication number Publication date
CH638537A5 (en) 1983-09-30
SU668611A3 (ru) 1979-06-15
ES468572A1 (es) 1978-12-01
FR2386557A1 (fr) 1978-11-03
EG13249A (en) 1980-12-31
SE7803837L (sv) 1978-10-07
GB1602266A (en) 1981-11-11
DK153378A (da) 1978-10-07
FI781053A (fi) 1978-10-07
CA1113452A (en) 1981-12-01
PT67872B (fr) 1979-11-14
DD135082A5 (de) 1979-04-11
JPS53149963A (en) 1978-12-27
NL7803188A (nl) 1978-10-10
AU3481178A (en) 1979-10-11
PL205800A1 (pl) 1979-01-29
IT7821995A0 (it) 1978-04-05
NO781200L (no) 1978-10-09
PL114096B1 (en) 1981-01-31
FR2386557B1 (sv) 1980-02-01
NZ186745A (en) 1980-10-24
PT67872A (fr) 1978-05-01
IT1094296B (it) 1985-07-26
RO81076B1 (ro) 1983-01-30
ZA781977B (en) 1979-03-28
IE46602B1 (en) 1983-07-27
BG28578A3 (bg) 1980-05-15
IL54443A0 (en) 1978-07-31
IE780672L (en) 1978-10-06
BE865760A (fr) 1978-10-06
LU79375A1 (de) 1978-07-13
ATA239978A (de) 1981-06-15
RO81076A2 (ro) 1983-02-01
DE2715853A1 (de) 1978-10-19

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