CR9512A - Metodos para el tratamiento de tumores de cerebro con anticuerpos - Google Patents

Metodos para el tratamiento de tumores de cerebro con anticuerpos

Info

Publication number
CR9512A
CR9512A CR9512A CR9512A CR9512A CR 9512 A CR9512 A CR 9512A CR 9512 A CR9512 A CR 9512A CR 9512 A CR9512 A CR 9512A CR 9512 A CR9512 A CR 9512A
Authority
CR
Costa Rica
Prior art keywords
treatment
antibodies
methods
brain tumors
brain
Prior art date
Application number
CR9512A
Other languages
English (en)
Inventor
Kyung Jin Kim
Terra John La
Bachchu Lal
Original Assignee
Galaxy Biotech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galaxy Biotech Llc filed Critical Galaxy Biotech Llc
Publication of CR9512A publication Critical patent/CR9512A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053—Skin, nerves, brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion es concerniente con un metodo para el tratamiento de un cerebro de tumor en un paciente, que comprende administrar sistemicamente un anticuerpo monocional.
CR9512A 2005-06-02 2007-11-12 Metodos para el tratamiento de tumores de cerebro con anticuerpos CR9512A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68711805P 2005-06-02 2005-06-02
US75109205P 2005-12-15 2005-12-15

Publications (1)

Publication Number Publication Date
CR9512A true CR9512A (es) 2008-04-16

Family

ID=37482322

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9512A CR9512A (es) 2005-06-02 2007-11-12 Metodos para el tratamiento de tumores de cerebro con anticuerpos

Country Status (14)

Country Link
US (2) US20070036797A1 (es)
EP (1) EP1885400A4 (es)
JP (2) JP2008545753A (es)
KR (1) KR20080026562A (es)
AU (1) AU2006252419B2 (es)
BR (1) BRPI0611009A2 (es)
CA (1) CA2607699A1 (es)
CR (1) CR9512A (es)
IL (1) IL187318A0 (es)
MA (1) MA29570B1 (es)
MX (1) MX2007015056A (es)
NO (1) NO20080012L (es)
RU (1) RU2007146986A (es)
WO (1) WO2006130773A2 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040208876A1 (en) * 2003-04-18 2004-10-21 Kim Kyung Jin Monoclonal antibodies to hepatocyte growth factor
US8124738B2 (en) * 2005-09-26 2012-02-28 Medarex, Inc. Human monoclonal antibodies to CD70
AR059922A1 (es) * 2006-04-01 2008-05-07 Galaxy Biotech Llc Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos
BRPI0712222B1 (pt) * 2006-06-02 2021-10-13 Aveo Pharmaceuticals, Inc. Proteína de ligação isolada que se liga ao fator de crescimento de hepatócito humano (hgf), seu uso e método de produção, ácido nucléico, vetor de expressão, célula hospedeira, e métodos para produzir um polipeptídeo que compreende uma região variável da cadeia pesada de imunoglobulina e para produzir um polipeptídeo que compreende uma região variável da cadeia leve de imunoglobulina
EP2380908A1 (en) 2006-06-02 2011-10-26 Aveo Pharmaceuticals, Inc. Hepatocyte growth factor (hgf) binding proteins
MX2009003229A (es) * 2006-09-29 2009-06-18 Oncomed Pharm Inc Composiciones y metodos para diagnosticar y tratar cancer.
WO2008074004A2 (en) * 2006-12-14 2008-06-19 Medarex, Inc. Human antibodies that bind cd70 and uses thereof
BRPI0816142A2 (pt) * 2007-08-24 2015-02-18 Novartis Ag Modulador de nrg1 para tratamento de distúrbios respiratórios.
TW200948380A (en) * 2008-04-11 2009-12-01 Galaxy Biotech Llc Combination of HGF inhibitor and PTEN agonist to treat cancer
US20110217294A1 (en) * 2008-04-11 2011-09-08 Daniel Fults Combination of hgf inhibitor and hedgehog inhibitor to treat cancer
CA2725873C (en) * 2008-05-29 2018-05-01 Galaxy Biotech, Llc Monoclonal antibodies to basic fibroblast growth factor
US20120052064A1 (en) 2009-04-17 2012-03-01 Yuuki Ito Anti-hgf antibody combinational cancer therapies
PT2488204E (pt) 2009-10-16 2016-06-09 Oncomed Pharm Inc Combinação terapêutica e utilização de anticorpos antagonistas de dll4 e agentes anti-hipertensivos
SI2536748T1 (sl) * 2010-02-18 2014-12-31 Genentech, Inc. Nevrogulinski antagonisti in njihova uporaba pri zdravljenju raka
US20130315895A1 (en) * 2010-07-01 2013-11-28 Takeda Pharmaceutical Company Limited COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET
US8551479B2 (en) 2010-09-10 2013-10-08 Oncomed Pharmaceuticals, Inc. Methods for treating melanoma
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
KR20190112175A (ko) 2010-12-01 2019-10-02 앨더바이오 홀딩스 엘엘씨 항―ｎｇｆ 조성물 및 그의 용도
WO2013044215A1 (en) 2011-09-23 2013-03-28 Oncomed Pharmaceuticals, Inc. Vegf/dll4 binding agents and uses thereof
WO2014071018A1 (en) 2012-10-31 2014-05-08 Oncomed Pharmaceuticals, Inc. Methods and monitoring of treatment with a dll4 antagonist
EP3212233B1 (en) 2014-10-31 2020-06-24 Oncomed Pharmaceuticals, Inc. Combination therapy for treatment of disease
US11339213B2 (en) 2015-09-23 2022-05-24 Mereo Biopharma 5, Inc. Methods and compositions for treatment of cancer

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2564486B2 (ja) * 1986-07-14 1996-12-18 修治 橋本 肝細胞増殖因子
US6498144B1 (en) * 1993-10-18 2002-12-24 North Shore - Long Island Jewish Research Institute Use of scatter factor to enhance angiogenesis
US5837676A (en) * 1993-10-18 1998-11-17 Long Island Jewish Medical Center Use of scatter factor to enhance angiogenesis
US5707624A (en) * 1994-06-03 1998-01-13 The Regents Of The University Of Michigan Treatment of Kaposi's sarcoma by inhibition of scatter factor
US5646036A (en) * 1995-06-02 1997-07-08 Genentech, Inc. Nucleic acids encoding hepatocyte growth factor receptor antagonist antibodies
US5686292A (en) * 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
US6214344B1 (en) * 1995-06-02 2001-04-10 Genetech, Inc. Hepatocyte growth factor receptor antagonists and uses thereof
DK0922102T3 (da) * 1996-07-03 2010-08-16 Genentech Inc Receptor-agonister af hepatocyt-vækstfaktor og anvendelser deraf
WO2004019991A2 (en) * 2002-08-30 2004-03-11 F. Hoffmann-La Roche Ag Scatter factor/hepatocyte growth factor antagonist nk4 for the treatment of glioma
US20040208876A1 (en) * 2003-04-18 2004-10-21 Kim Kyung Jin Monoclonal antibodies to hepatocyte growth factor
US7220410B2 (en) * 2003-04-18 2007-05-22 Galaxy Biotech, Llc Monoclonal antibodies to hepatocyte growth factor
CN101124240B (zh) * 2003-07-18 2013-12-18 安姆根有限公司 肝细胞生长因子的特异性结合物
SI2392565T1 (sl) * 2003-09-26 2014-05-30 Exelixis, Inc. c-Met modulatorji in postopki uporabe
US7977345B2 (en) * 2004-07-02 2011-07-12 Exelixis, Inc. c-MET modulators and method of use
WO2007056523A2 (en) * 2005-11-08 2007-05-18 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Methods for diagnosing and monitoring the progression of cancer
AR059922A1 (es) * 2006-04-01 2008-05-07 Galaxy Biotech Llc Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos
TW201002346A (en) * 2008-04-11 2010-01-16 Galaxy Biotech Llc Combination of HGF inhibitor and EGF inhibitor to treat cancer
US20110217294A1 (en) * 2008-04-11 2011-09-08 Daniel Fults Combination of hgf inhibitor and hedgehog inhibitor to treat cancer

Also Published As

Publication number Publication date
MA29570B1 (fr) 2008-06-02
EP1885400A2 (en) 2008-02-13
IL187318A0 (en) 2008-04-13
JP2008545753A (ja) 2008-12-18
WO2006130773A2 (en) 2006-12-07
EP1885400A4 (en) 2011-01-26
AU2006252419A1 (en) 2006-12-07
US20070036797A1 (en) 2007-02-15
BRPI0611009A2 (pt) 2010-08-10
AU2006252419B2 (en) 2012-02-02
WO2006130773A3 (en) 2009-04-16
MX2007015056A (es) 2008-03-11
CA2607699A1 (en) 2006-12-07
JP2013136580A (ja) 2013-07-11
US20100221250A1 (en) 2010-09-02
RU2007146986A (ru) 2009-06-27
NO20080012L (no) 2008-02-20
KR20080026562A (ko) 2008-03-25

Similar Documents

Publication Publication Date Title
CR9512A (es) Metodos para el tratamiento de tumores de cerebro con anticuerpos
CY1112953T1 (el) Χρηση των αντι-cd100 αντισωματων
CY1119454T1 (el) Αντισωματα εναντι cd38 για τη θεραπεια του πολλαπλου μυελωματος
CR10590A (es) Terapia tumoral con un anticuerpo anti-vefg
MY147217A (en) Antibody molecules having specificity for human il-06
EA200900040A1 (ru) Молекулы антител, которые связываются с человеческим il-17
TW200621801A (en) Antibody molecules having specificity for human IL-17
CR8380A (es) Metodos para preparar y utilizar compuestos novedosos de celulas madre y sus conjuntos
AR051528A1 (es) Anticuerpos humanizados que reconocen el peptido beta amiloideo
CR10468A (es) Inmunoglobulinas
CR20130016A (es) ANTICUERPOS PEPTIDICOS BETA AMILOIDE ANTI-N3pGlu Y USOS DE LOS MISMOS
GT201200318A (es) Anticuerpos hacia gdf8 humano
UY29284A1 (es) Anticuerpos ab(beta) humanizados usados en mejorar la cognicion
EA200900492A1 (ru) Молекулы антител, которые связываются с il-17a и il-17f
ECSP14001260A (es) Inmunoligantes biespecificos dirigidos contra tnf e il-17 referencia cruzada a solicitudes relacionadas
BRPI0606108A2 (pt) processo de tratamento
TW200738270A (en) Method of treating depression using a TNFα antibody
GT200500276A (es) Metodo para el tratamiento de la vasculitis
EP1912674A4 (en) BIS SPECIFIC SINGLE CHAIN FV ANTIBODY MOLECULES AND METHOD OF USE THEREOF
HK1243943A1 (zh) 使用抗IL-1α抗體治療癌症
AR092818A1 (es) Anticuerpo tau humanizado
EA200901211A1 (ru) Антигены белка с5 и их применение
CY1114050T1 (el) Μονοκλωνικα αντισωματα εναντι claudin-18 στην αγωγη εναντι καρκινου
AR052284A1 (es) Variantes de un anticuerpo y usos de las mismas
EA201171060A1 (ru) Молекулы антител, обладающих специфичностью к человеческому ох40

Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)