CR6712A - Inhibidores duales de la sintesis de esteres de colesterilo y de esteres de cera para transtornos de las glandulas sebaceas - Google Patents

Inhibidores duales de la sintesis de esteres de colesterilo y de esteres de cera para transtornos de las glandulas sebaceas

Info

Publication number
CR6712A
CR6712A CR6712A CR6712A CR6712A CR 6712 A CR6712 A CR 6712A CR 6712 A CR6712 A CR 6712A CR 6712 A CR6712 A CR 6712A CR 6712 A CR6712 A CR 6712A
Authority
CR
Costa Rica
Prior art keywords
acne
esteres
disorders
sebace
colesterilo
Prior art date
Application number
CR6712A
Other languages
English (en)
Inventor
Homan Reynold
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of CR6712A publication Critical patent/CR6712A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un metodo para tratar trastornos de las glandulas sebaceas, que comprende la administracion a un paciente que requiere dicho tratamiento, una cantidad efectiva de un compuesto llamado ester 2,6-diisopropilfenilico del acido ((2,4,6-triisopropil-fenil)-acetil)-sulfamico o una sal correspondiente, farmaceuticamente aceptable. Particularmente, metodos para tratar trastornos de las glandulas sebaceas son provistos, donde dichos desordenes se escogen del grupo formado por seborrea, acnes, dermatitis perioral, rosacea y lesiones acneiformes inducidas por corticosteroides. La presente invencion provee metodos para el tratamiento de acnes, como por ejemplo, cloroacne, acne ciliar, acne quistico, acne queratoso, acne vulgar, acne senil y acne medicamentoso.
CR6712A 2000-02-02 2002-07-24 Inhibidores duales de la sintesis de esteres de colesterilo y de esteres de cera para transtornos de las glandulas sebaceas CR6712A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17977800P 2000-02-02 2000-02-02

Publications (1)

Publication Number Publication Date
CR6712A true CR6712A (es) 2004-01-14

Family

ID=22657957

Family Applications (1)

Application Number Title Priority Date Filing Date
CR6712A CR6712A (es) 2000-02-02 2002-07-24 Inhibidores duales de la sintesis de esteres de colesterilo y de esteres de cera para transtornos de las glandulas sebaceas

Country Status (34)

Country Link
US (2) US6730703B2 (es)
EP (1) EP1263421B1 (es)
JP (1) JP2003531113A (es)
KR (1) KR20020073574A (es)
CN (1) CN1398182A (es)
AP (1) AP2002002612A0 (es)
AT (1) ATE295724T1 (es)
AU (1) AU781563B2 (es)
BG (1) BG107042A (es)
BR (1) BR0107954A (es)
CA (1) CA2398219A1 (es)
CR (1) CR6712A (es)
DE (1) DE60110897T2 (es)
DZ (1) DZ3288A1 (es)
EA (1) EA004255B1 (es)
EE (1) EE200200429A (es)
ES (1) ES2239145T3 (es)
GE (1) GEP20043286B (es)
HR (1) HRP20020717A2 (es)
HU (1) HUP0301010A3 (es)
IL (1) IL150865A0 (es)
IS (1) IS6478A (es)
MA (1) MA26872A1 (es)
MX (1) MXPA02007309A (es)
NO (1) NO20023659L (es)
NZ (1) NZ520330A (es)
OA (1) OA12173A (es)
PL (1) PL357041A1 (es)
PT (1) PT1263421E (es)
SK (1) SK10972002A3 (es)
UA (1) UA75345C2 (es)
WO (1) WO2001056556A2 (es)
YU (1) YU57502A (es)
ZA (1) ZA200206075B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1281399A3 (en) * 2001-08-01 2004-02-11 Warner-Lambert Company Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production
US20050031699A1 (en) 2003-06-26 2005-02-10 L'oreal Porous particles loaded with cosmetically or pharmaceutically active compounds
ATE409470T1 (de) 2003-10-09 2008-10-15 Warner Lambert Co Pharmazeutische zusammensetzungen mit malonamid- derivaten zur verringerung der talg-produktion
KR100906288B1 (ko) 2005-02-24 2009-07-06 워너-램버트 캄파니 엘엘씨 결정질 acat 억제제
FR2904002A1 (fr) * 2006-07-19 2008-01-25 Galderma Res & Dev S N C Snc Modulateurs de la lanosterol synthetase dans le traitement de l'acne ou de l'hyperseborrhee
FR2903999B1 (fr) * 2006-07-19 2008-09-05 Galderma Res & Dev S N C Snc Modulateurs de sc4mol dans le traitement de l'acne ou de l'hyperseborrhee
FR2938342A1 (fr) * 2008-11-13 2010-05-14 Galderma Res & Dev Ciblage de modulateurs de ces1 et/ou ces3 dans le traitement de l'acne, d'une dermatite seborrheique ou de l'hyperseborrhee
CA2750233A1 (en) 2009-01-28 2010-08-05 Nanobio Corporation Compositions for treatment and prevention of acne, methods of making the compositions, and methods of use thereof
JP2021527634A (ja) * 2018-06-21 2021-10-14 デルマバント サイエンシズ ゲーエムベーハー Dgat1阻害剤の局所製剤およびそれらの使用の方法

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4545977A (en) * 1985-01-11 1985-10-08 G. D. Searle & Co. Compositions and methods for treating severe acne with isotretinoin
US4751026A (en) 1986-03-24 1988-06-14 Warner-Lambert Company Substituted anilides of oleic, linoleic, or linolenic acid as inhibitors of acyl-coa:cholesterol acyltransferase
US4722927A (en) 1986-04-28 1988-02-02 Warner-Lambert Company Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase
EP0252524A3 (en) 1986-07-11 1989-04-19 Warner-Lambert Company Aryl- and aralkylamide- derivatives of omega- (substituted-phenyloxy)-alkanoic acids as inhibitors of acyl-coa: cholesterol acyltransferase and pharmaceuticals containing them
US4716175A (en) 1987-02-24 1987-12-29 Warner-Lambert Company Saturated fatty acid amides as inhibitors of acyl-CoA:cholesterol acyltransferase
IE61716B1 (en) 1987-06-02 1994-11-30 Warner Lambert Co Antihyperlipidemic and antiatherosclerotic urea compounds
US5015644A (en) 1987-06-02 1991-05-14 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds
EP0297610B1 (en) 1987-07-02 1991-03-13 Warner-Lambert Company N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase
US5116848A (en) 1988-03-30 1992-05-26 Warner-Lambert Company N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents
US4868210A (en) 1988-03-30 1989-09-19 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic compounds and compositions
US4948806A (en) 1988-03-30 1990-08-14 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic compounds and compositions
US5030653A (en) 1988-03-30 1991-07-09 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic compounds and compositions
US4999373A (en) 1988-03-30 1991-03-12 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic compounds and compositions
US4923896A (en) 1989-02-09 1990-05-08 Warner-Lambert Company N-(substituted aryl)-N'-(substituted alkoxy)-ureas and thioureas as antihypercholesterolemic and antiatherosclerotic agents
US5155127A (en) 1989-02-09 1992-10-13 Warner-Lambert Company N-(substituted aryl)-n'-(substituted alkoxy)-ureas and thioureas as antihypercholesterolemic and antiatherosclerotic agents
US4994465A (en) 1989-02-17 1991-02-19 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds
AU632809B2 (en) 1989-05-25 1993-01-14 Takeda Chemical Industries Ltd. Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof
CA2022346A1 (en) 1989-08-04 1991-02-05 Mitsubishi Chemical Corporation 1-phenylalkyl-3-phenylurea derivatives
WO1991004027A1 (en) 1989-09-15 1991-04-04 Pfizer Inc. New n-aryl and n-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme a: cholesterol acyl transferase (acat)
TW205037B (es) 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd
JPH05310678A (ja) 1990-01-22 1993-11-22 Mitsubishi Kasei Corp 1−フェニルアルキル−3−フェニル尿素誘導体
US5362878A (en) 1991-03-21 1994-11-08 Pfizer Inc. Intermediates for making N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase (ACAT)
ES2125325T3 (es) 1992-01-23 1999-03-01 Pfizer Derivados de 4-fenil-3-(heteroarilureido)-1,2-dihidro-2-oxoquinolina como agentes antihipercolesterolemicos y antiateroscleroticos.
CA2134359C (en) 1992-05-28 1997-07-01 Ernest S. Hamanaka New n-aryl and n-heteroarylurea derivatives as inhibitors of acyl coenzyme a: cholesterol acyl transferase (acat)
US5565472A (en) 1992-12-21 1996-10-15 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
US5491172A (en) * 1993-05-14 1996-02-13 Warner-Lambert Company N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
US5596001A (en) 1993-10-25 1997-01-21 Pfizer Inc. 4-aryl-3-(heteroarylureido)quinoline derivatves
US5494172A (en) * 1994-05-12 1996-02-27 Miller Compressing Company Magnetic pulley assembly
US6133326A (en) 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production
EP1090014B1 (en) * 1998-06-25 2003-09-03 Tularik Inc. Arylsulfonanilide phosphates
PE20020453A1 (es) * 2000-09-27 2002-06-06 Merck & Co Inc Derivados del acido benzopirancarboxilico para el tratamiento de la diabetes y los trastornos de lipidos

Also Published As

Publication number Publication date
UA75345C2 (en) 2006-04-17
SK10972002A3 (sk) 2003-07-01
AP2002002612A0 (en) 2002-09-30
CN1398182A (zh) 2003-02-19
DE60110897D1 (de) 2005-06-23
EP1263421B1 (en) 2005-05-18
US20030060507A1 (en) 2003-03-27
KR20020073574A (ko) 2002-09-27
MXPA02007309A (es) 2002-11-29
GEP20043286B (en) 2004-07-26
ZA200206075B (en) 2003-10-30
DE60110897T2 (de) 2006-03-23
DZ3288A1 (en) 2001-08-09
HUP0301010A3 (en) 2005-03-29
YU57502A (sh) 2006-01-16
OA12173A (en) 2006-05-08
EP1263421A2 (en) 2002-12-11
JP2003531113A (ja) 2003-10-21
WO2001056556A2 (en) 2001-08-09
NO20023659L (no) 2002-09-25
US6730703B2 (en) 2004-05-04
CA2398219A1 (en) 2001-08-09
BR0107954A (pt) 2002-10-22
BG107042A (bg) 2003-04-30
ES2239145T3 (es) 2005-09-16
EA200200764A1 (ru) 2002-12-26
AU781563B2 (en) 2005-06-02
EE200200429A (et) 2003-12-15
US20040161393A1 (en) 2004-08-19
EA004255B1 (ru) 2004-02-26
HRP20020717A2 (en) 2003-12-31
PL357041A1 (en) 2004-07-12
PT1263421E (pt) 2005-08-31
AU2971801A (en) 2001-08-14
ATE295724T1 (de) 2005-06-15
MA26872A1 (fr) 2004-12-20
NO20023659D0 (no) 2002-08-01
IS6478A (is) 2002-07-19
HUP0301010A2 (hu) 2003-08-28
WO2001056556A3 (en) 2002-03-07
NZ520330A (en) 2004-02-27
IL150865A0 (en) 2003-02-12

Similar Documents

Publication Publication Date Title
ATE208397T1 (de) Arylsubstituierte 5,5 verknüpfte aromatische nitroverbindungen als entzündungshemmende wirkstoffe
CR6712A (es) Inhibidores duales de la sintesis de esteres de colesterilo y de esteres de cera para transtornos de las glandulas sebaceas
BR0318498A (pt) composições terapêuticas à base de porìfero para o tratamento e a prevenção de doenças da pele
BRPI0406592A (pt) Usos de n-desmetilclozapina, métodos para o tratamento de psicose, de distúrbios afetivos, de demência, de dor neuropática e de glaucoma e composição farmacêutica
EP1281399A3 (en) Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production
ES2191069T3 (es) Diaril-2-(5h)-furanonas como inhibidores de cox-2.
CR8411A (es) Metodo para el tratamiento de la enfermedad asociada con adamts-5
CA2157142A1 (en) Treatment of diseases caused by sebaceous gland disorders
CO5590913A2 (es) Terapia de combinacion antivirica
BRPI0114344B8 (pt) composto retinóide, seu uso, sua composição farmacêutica e seu processo de preparação
NO20083637L (no) anvendelse av alkandikarboksylsyrer og retinoider for behandling av rosacea og andre inflammatoriske hudsykdommer
RU94037233A (ru) Применение 2-фенил-3-ароилбензотиофенов для лечения лекарственноустойчивых новообразований
BRPI0412424A (pt) composto, composição farmacêutica, método para tratar doenças dermatológicas ou cancerosas em um mamìfero, composição, e, método para tratar doenças relacionadas com a pele ou cancerosas
ES2181849T3 (es) Procedimiento para minimizar la perdida osea.
US11491128B2 (en) Reversible nitroxide derivatives of nitroalkenes that mediate nitrosating and alkylating reactions
CZ63295A3 (en) 1 alpha-fluoro-25-hydroxy-16-en-23-in-cholecalciferol as such and for the use as a therapeutic active compound, its use for the preparation of a pharmaceutical preparation, process of its preparation and a pharmaceutical preparation based thereon
BR0309032A (pt) Método para tratar sintomas vasomotores, a menopausa, deficiências hormonais em um paciente, e para tratar um paciente que sofre de sintomas vasomotores
ATE357225T1 (de) Methode zur behandlung von rosacea durch topische verabreichung eines cyclohexanderivats
BR9910095A (pt) Compostos inibidores de spla2 para tratamento de doença
BR0109799A (pt) Medicamento para estimular a leucopoese, para tratamento de doenças tumorais e protozoárias, de acarinose, artropodìase e processo para produção do mesmo
ES2139013T3 (es) Compuestos de fosfonato que contienen nitrogeno cuaternario para tratar el metabolismo anormal del calcio y fosfato.
AU2003258553A1 (en) Metal cluster nano-compounds for treating tumor diseases
NO20016000L (no) Aminotetralin-derivat for terapien av kardiovaskul¶re sykdommer
PT865278E (pt) Utilizacao de 1-hidroxi-2-piridonas para o tratamento de doencas terapeuticamente dificeis de mucosidade da pele
BR9803065A (pt) Processo de isolamento e purificação do éster-etila do ácido eicosapentaenóico e produto fármaco resultante

Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)