CR20140158A - Línea de proceso para la producción de partículas criodesecadas - Google Patents
Línea de proceso para la producción de partículas criodesecadasInfo
- Publication number
- CR20140158A CR20140158A CR20140158A CR20140158A CR20140158A CR 20140158 A CR20140158 A CR 20140158A CR 20140158 A CR20140158 A CR 20140158A CR 20140158 A CR20140158 A CR 20140158A CR 20140158 A CR20140158 A CR 20140158A
- Authority
- CR
- Costa Rica
- Prior art keywords
- production
- particles
- process line
- criodesecated
- cryo
- Prior art date
Links
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
- F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised
Landscapes
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Drying Of Solid Materials (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Oxygen, Ozone, And Oxides In General (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
Abstract
Una línea de proceso (300) para la producción de partículas criodesecadas bajo condiciones cerradas que comprende al menos una cámara de aspersión (302) para la generación de gotitas y criocongelación de las gotitas de líquido para formar partículas y un criodesecador a granel (304).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11008057.9A EP2578974A1 (en) | 2011-10-05 | 2011-10-05 | Process line for the production of freeze-dried particles |
PCT/EP2012/004162 WO2013050156A1 (en) | 2011-10-05 | 2012-10-04 | Process line for the production of freeze-dried particles |
Publications (1)
Publication Number | Publication Date |
---|---|
CR20140158A true CR20140158A (es) | 2014-10-30 |
Family
ID=46980888
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20140158A CR20140158A (es) | 2011-10-05 | 2014-04-04 | Línea de proceso para la producción de partículas criodesecadas |
CR20140159A CR20140159A (es) | 2011-10-05 | 2014-04-04 | Línea de proceso para la producción de partículas criodesecadas |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20140159A CR20140159A (es) | 2011-10-05 | 2014-04-04 | Línea de proceso para la producción de partículas criodesecadas |
Country Status (25)
Country | Link |
---|---|
US (2) | US10006706B2 (es) |
EP (4) | EP2578974A1 (es) |
JP (2) | JP5728135B2 (es) |
KR (2) | KR101512608B1 (es) |
CN (2) | CN103917842B (es) |
AU (2) | AU2012320854B2 (es) |
BR (2) | BR112014008001B1 (es) |
CA (2) | CA2849799C (es) |
CO (2) | CO6930306A2 (es) |
CR (2) | CR20140158A (es) |
DK (2) | DK2764309T3 (es) |
EA (2) | EA027602B1 (es) |
ES (2) | ES2608478T3 (es) |
HK (2) | HK1199656A1 (es) |
HU (2) | HUE029973T2 (es) |
IL (2) | IL231849A0 (es) |
IN (2) | IN2014CN02440A (es) |
MX (2) | MX359904B (es) |
MY (2) | MY152319A (es) |
PE (2) | PE20142141A1 (es) |
PL (2) | PL2766682T3 (es) |
SG (2) | SG11201400640VA (es) |
UA (2) | UA111858C2 (es) |
WO (2) | WO2013050156A1 (es) |
ZA (1) | ZA201401930B (es) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140083628A1 (en) | 2012-09-27 | 2014-03-27 | Velico Medical, Inc. | Spray drier assembly for automated spray drying |
EP2578974A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Process line for the production of freeze-dried particles |
EP2578975A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum freeze-dryer |
EP2578976A1 (en) | 2011-10-06 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum for use in a vacuum freeze-dryer |
UA111631C2 (uk) | 2011-10-06 | 2016-05-25 | Санофі Пастер Са | Нагрівальний пристрій для роторної барабанної ліофільної сушарки |
WO2014190992A1 (en) | 2013-05-29 | 2014-12-04 | Gea Process Engineering A/S | Method of providing inline sterile freeze drying of a product in trays accommodated in a trolley, system for carrying out the method, and use of the method |
DK3171954T3 (en) * | 2014-07-21 | 2018-08-06 | Sanofi Pasteur Sa | LIQUID APPLICATION FOR THE GENERATION OF DROPS AND ITS USE FOR PREPARING A VACCINE COMPOSITION |
US9561184B2 (en) | 2014-09-19 | 2017-02-07 | Velico Medical, Inc. | Methods and systems for multi-stage drying of plasma |
DE102015105375B4 (de) * | 2015-01-07 | 2016-11-03 | Richard Süverkrüp | Vorrichtung und Verfahren zur Erzeugung monodisperser gefrorener Tropfen |
US9739532B2 (en) * | 2015-02-04 | 2017-08-22 | Steven F. Baugh | Botanical freeze drying system and method |
US10465985B2 (en) | 2015-06-01 | 2019-11-05 | Ima Life North America Inc. | Bulk freeze drying using spray freezing and agitated drying with dielectric heating |
RU2615553C1 (ru) * | 2015-10-15 | 2017-04-05 | Акционерное общество "Военно-промышленная корпорация "Научно-производственное объединение машиностроения" | Способ и устройство непрерывной сублимационной сушки жидких продуктов |
EP3167877A1 (en) * | 2015-11-12 | 2017-05-17 | Bayer Pharma Aktiengesellschaft | Method for the production of freeze-dried pellets comprising factor viii |
CN106705574A (zh) * | 2015-11-17 | 2017-05-24 | 上海东富龙科技股份有限公司 | 一种固体制剂制造设备和方法 |
JP6666535B2 (ja) * | 2016-01-05 | 2020-03-18 | 株式会社あい・あいエナジーアソシエイツ | 液体の凍結乾燥装置及び凍結乾燥方法 |
CN105674691B (zh) * | 2016-04-01 | 2017-11-21 | 苏州大学 | 用于收集喷雾冷冻冰球颗粒的双密封式设备及其收集方法 |
US10369077B2 (en) * | 2017-05-31 | 2019-08-06 | Adienne Pharma & Biotech Sa | Multi chamber flexible bag and methods of using the same |
US10507165B2 (en) | 2017-05-31 | 2019-12-17 | Adienne Pharma & Biotech Sa | Multi chamber flexible bag and methods of using same |
DE102017119649A1 (de) | 2017-08-28 | 2019-02-28 | Richard Süverkrüp | Verfahren zur kontinuierlichen Herstellung gefriergetrockneter Tropfen in einem geschlossenen Gaskreislauf |
ES2779023T3 (es) * | 2017-10-20 | 2020-08-13 | Martin Christ Gefriertrocknungsanlagen Gmbh | Procedimiento para la determinación a base de presión de un parámetro de producto en un liofilizador, liofilizador y producto de software |
KR102450460B1 (ko) * | 2017-12-29 | 2022-09-30 | 아주대학교산학협력단 | 초음파 분무기를 이용한 미립구 약제의 양산 시스템 |
JP7038435B2 (ja) * | 2018-03-13 | 2022-03-18 | 株式会社プリス | 噴霧凍結造粒乾燥粉体製造装置及び噴霧凍結造粒乾燥粉体製造システム |
CN111065874B (zh) * | 2018-06-08 | 2020-12-29 | 株式会社爱发科 | 真空冻结干燥装置和真空冻结干燥方法 |
CA3105256A1 (en) * | 2018-07-05 | 2020-01-09 | Bayer Aktiengesellschaft | Novel stable high-concentration formulation for anti-fxia antibodies |
WO2020161863A1 (ja) * | 2019-02-07 | 2020-08-13 | 株式会社アルバック | 真空凍結乾燥方法及び真空凍結乾燥装置 |
US11243029B2 (en) * | 2019-04-26 | 2022-02-08 | Purdue Research Foundation | Process monitoring and control for lyophilization using a wireless sensor network |
CN111207564B (zh) * | 2019-09-30 | 2022-01-04 | 中国科学院上海硅酸盐研究所 | 一种冷冻干燥***及方法 |
JP6777350B1 (ja) | 2020-05-18 | 2020-10-28 | 株式会社エムアイアイ | 真空凍結乾燥装置及び真空凍結乾燥方法 |
TW202202792A (zh) * | 2020-05-18 | 2022-01-16 | 日商Mii股份有限公司 | 真空凍結乾燥裝置及真空凍結乾燥方法 |
JP6887050B1 (ja) * | 2020-08-07 | 2021-06-16 | 株式会社アルバック | 真空凍結乾燥方法および真空凍結乾燥装置 |
WO2022030055A1 (ja) * | 2020-08-07 | 2022-02-10 | 株式会社アルバック | 真空凍結乾燥方法、真空凍結乾燥装置用の噴射ノズルおよび真空凍結乾燥装置 |
CA3173146C (en) | 2020-11-16 | 2023-10-31 | Joel Peter LENNON-MEYER | Continuous throughput lyophilizer/powder filler within a sterile boundary |
JP7085088B1 (ja) * | 2021-08-03 | 2022-06-16 | 株式会社エムアイアイ | 凍結乾燥物 |
WO2023057444A1 (en) | 2021-10-05 | 2023-04-13 | Sanofi | METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPs) AND LNPs OBTAINED WITH THE SAME |
US20230122361A1 (en) * | 2021-10-20 | 2023-04-20 | DSM Sales & Manufacturing, Inc. | Freeze-drying systems and methods |
WO2023242347A1 (en) | 2022-06-15 | 2023-12-21 | Sanofi | Highly concentrated antibody compositions |
US11975274B2 (en) | 2022-09-15 | 2024-05-07 | Velico Medical, Inc. | Blood plasma product |
US11841189B1 (en) | 2022-09-15 | 2023-12-12 | Velico Medical, Inc. | Disposable for a spray drying system |
US11998861B2 (en) | 2022-09-15 | 2024-06-04 | Velico Medical, Inc. | Usability of a disposable for a spray drying plasma system |
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US2388917A (en) * | 1941-10-13 | 1945-11-13 | Hormel & Co Geo A | Process for preservation of biological materials and products resulting therefrom |
FR1378749A (fr) * | 1964-01-07 | 1964-11-13 | Leybold Hochvakuum Anlagen | Procédé et dispositif de séchage par congélation |
US3303578A (en) | 1964-07-29 | 1967-02-14 | William C Rockwell | Continuous freeze-drying apparatus |
US3601901A (en) | 1969-09-12 | 1971-08-31 | Earl L Rader | Freeze drying apparatus with removable conveyor and heater structures |
US3621587A (en) | 1970-08-06 | 1971-11-23 | Smitherm Industries | Freeze drying apparatus |
US4033048A (en) | 1976-01-12 | 1977-07-05 | Clayton Van Ike | Freeze drying apparatus |
JPS5844703Y2 (ja) | 1979-02-01 | 1983-10-11 | クラリオン株式会社 | スピ−カの取付構造 |
JPS55112980A (en) * | 1979-02-26 | 1980-09-01 | Nippon Oxygen Co Ltd | Freezing drier |
DE3105623A1 (de) * | 1981-02-16 | 1982-09-02 | Erhard Dipl.-Ing.agr. 8000 München Grolitsch | Verfahren zur schonenden gefriertrocknung und pulverisierung von empfindlichen trocknungsguetern wie wasserhaltigen lebensmitteln |
CA2051092C (en) | 1990-09-12 | 2002-07-23 | Stephen A. Livesey | Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions |
DE4113512C2 (de) * | 1991-04-25 | 1995-04-20 | Grolitsch Lisbeth | Verfahren und Vorrichtung zur Gefriertrocknung und Pulverisierung von Lebensmitteln |
US5230162A (en) * | 1992-06-26 | 1993-07-27 | Oyler Jr James R | Systems and methods for the deliquification of liquid-containing substances by flash sublimation |
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DE19654134C2 (de) | 1996-04-25 | 2003-08-07 | Messer Griesheim Gmbh | Verfahren und Einrichtung zum Gefriertrocknen |
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BR0214279A (pt) * | 2001-11-19 | 2005-12-20 | Becton Dickinson Co | Composições farmacêuticas em forma particulada |
JP3942093B2 (ja) | 2003-01-28 | 2007-07-11 | 株式会社アルバック | 噴霧式真空凍結乾燥装置 |
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DE102004005660A1 (de) * | 2004-02-04 | 2005-08-25 | Rheinische Friedrich-Wilhelms-Universität Bonn | Verfahren und Vorrichtung zur Herstellung eines lyophilisierten pharmazeutischen Materials |
SE526792C2 (sv) * | 2004-03-03 | 2005-11-08 | Tetra Laval Holdings & Finance | Anordning för evaporativ kylning av en vätskeformig produkt |
EP1742716A4 (en) | 2004-05-01 | 2009-02-25 | Agres Ltd | DRYING PROCESS AND DEVICE |
US7836606B2 (en) | 2004-07-23 | 2010-11-23 | Bayer Technology Services Gmbh | Sterile freezing, drying, storing, assaying and filling process |
US20060165717A1 (en) | 2005-01-25 | 2006-07-27 | Sanofi Pasteur | DCchol in newborns |
AR054822A1 (es) | 2005-07-07 | 2007-07-18 | Sanofi Pasteur | Emulsion inmuno adyuvante |
US20070218138A1 (en) * | 2006-03-20 | 2007-09-20 | Bittorf Kevin J | Pharmaceutical Compositions |
PL2043682T3 (pl) | 2006-07-17 | 2014-09-30 | Glaxosmithkline Biologicals Sa | Szczepionka przeciw grypie |
DE102007055488B4 (de) * | 2006-12-01 | 2015-01-22 | Püschner GmbH + Co. KG | Mikrowellen-Vakuumtrocknungsanlage zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut |
DE202006018276U1 (de) * | 2006-12-01 | 2007-02-08 | Püschner GmbH + Co. KG | Mikrowellen-Vakuumtrockungsanlage zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut |
CN101234257B (zh) | 2007-02-01 | 2011-07-27 | 发泰(天津)科技有限公司 | 微波旋转薄膜浓缩器 |
DE102007012795B3 (de) * | 2007-03-16 | 2008-04-10 | Püschner GmbH + Co. KG | Mikrowellen-Vakuumtrocknungsanlagen und Verfahren zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut mittels Mikrowellen |
EP2101131A1 (en) * | 2007-12-31 | 2009-09-16 | Terruzzi Fercalx S.p.A. | Lyophilization method and system therefor |
CA2716399C (en) | 2008-03-05 | 2020-07-21 | Pierre Chouvenc | Process for stabilizing an adjuvant containing vaccine composition |
EP2578975A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum freeze-dryer |
EP2578974A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Process line for the production of freeze-dried particles |
UA111631C2 (uk) | 2011-10-06 | 2016-05-25 | Санофі Пастер Са | Нагрівальний пристрій для роторної барабанної ліофільної сушарки |
EP2578976A1 (en) | 2011-10-06 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum for use in a vacuum freeze-dryer |
-
2011
- 2011-10-05 EP EP11008057.9A patent/EP2578974A1/en not_active Withdrawn
-
2012
- 2012-04-10 UA UAA201404683A patent/UA111858C2/uk unknown
- 2012-04-10 UA UAA201404685A patent/UA111859C2/uk unknown
- 2012-10-04 CA CA2849799A patent/CA2849799C/en not_active Expired - Fee Related
- 2012-10-04 PE PE2014000480A patent/PE20142141A1/es not_active Application Discontinuation
- 2012-10-04 JP JP2014533796A patent/JP5728135B2/ja active Active
- 2012-10-04 MY MYPI2014000783 patent/MY152319A/en unknown
- 2012-10-04 CA CA2849802A patent/CA2849802C/en not_active Expired - Fee Related
- 2012-10-04 BR BR112014008001-1A patent/BR112014008001B1/pt active IP Right Grant
- 2012-10-04 CN CN201280049534.2A patent/CN103917842B/zh active Active
- 2012-10-04 PE PE2014000479A patent/PE20141979A1/es not_active Application Discontinuation
- 2012-10-04 SG SG11201400640VA patent/SG11201400640VA/en unknown
- 2012-10-04 WO PCT/EP2012/004162 patent/WO2013050156A1/en active Application Filing
- 2012-10-04 MX MX2014004041A patent/MX359904B/es active IP Right Grant
- 2012-10-04 WO PCT/EP2012/004168 patent/WO2013050162A1/en active Application Filing
- 2012-10-04 EP EP12769021.2A patent/EP2764309B1/en active Active
- 2012-10-04 EP EP16199831.5A patent/EP3211355A1/en not_active Withdrawn
- 2012-10-04 MY MYPI2014000743 patent/MY151369A/en unknown
- 2012-10-04 EA EA201490723A patent/EA027602B1/ru not_active IP Right Cessation
- 2012-10-04 EA EA201490719A patent/EA027630B1/ru not_active IP Right Cessation
- 2012-10-04 HU HUE12769026A patent/HUE029973T2/en unknown
- 2012-10-04 ES ES12769026.1T patent/ES2608478T3/es active Active
- 2012-10-04 DK DK12769021.2T patent/DK2764309T3/en active
- 2012-10-04 CN CN201280049533.8A patent/CN103917841B/zh active Active
- 2012-10-04 DK DK12769026.1T patent/DK2766682T3/en active
- 2012-10-04 EP EP12769026.1A patent/EP2766682B1/en active Active
- 2012-10-04 AU AU2012320854A patent/AU2012320854B2/en active Active
- 2012-10-04 PL PL12769026T patent/PL2766682T3/pl unknown
- 2012-10-04 JP JP2014533792A patent/JP5766361B2/ja active Active
- 2012-10-04 PL PL12769021T patent/PL2764309T3/pl unknown
- 2012-10-04 SG SG11201400641QA patent/SG11201400641QA/en unknown
- 2012-10-04 US US14/348,869 patent/US10006706B2/en active Active
- 2012-10-04 BR BR112014007862-9A patent/BR112014007862B1/pt active IP Right Grant
- 2012-10-04 MX MX2014004000A patent/MX341894B/es active IP Right Grant
- 2012-10-04 HU HUE12769021A patent/HUE030970T2/en unknown
- 2012-10-04 KR KR1020147011244A patent/KR101512608B1/ko active IP Right Grant
- 2012-10-04 IN IN2440CHN2014 patent/IN2014CN02440A/en unknown
- 2012-10-04 IN IN2407CHN2014 patent/IN2014CN02407A/en unknown
- 2012-10-04 KR KR1020147011243A patent/KR101552804B1/ko active IP Right Grant
- 2012-10-04 AU AU2012320848A patent/AU2012320848B8/en not_active Ceased
- 2012-10-04 US US14/348,877 patent/US9920989B2/en active Active
- 2012-10-04 ES ES12769021.2T patent/ES2608427T3/es active Active
-
2014
- 2014-03-17 ZA ZA2014/01930A patent/ZA201401930B/en unknown
- 2014-03-31 IL IL231849A patent/IL231849A0/en unknown
- 2014-03-31 IL IL231853A patent/IL231853A0/en unknown
- 2014-04-04 CO CO14073110A patent/CO6930306A2/es unknown
- 2014-04-04 CR CR20140158A patent/CR20140158A/es unknown
- 2014-04-04 CR CR20140159A patent/CR20140159A/es unknown
- 2014-04-04 CO CO14073108A patent/CO6930351A2/es unknown
-
2015
- 2015-01-06 HK HK15100076.0A patent/HK1199656A1/xx not_active IP Right Cessation
- 2015-01-20 HK HK15100624.7A patent/HK1200207A1/xx not_active IP Right Cessation
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