CR10402A - Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1 - Google Patents
Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1Info
- Publication number
- CR10402A CR10402A CR10402A CR10402A CR10402A CR 10402 A CR10402 A CR 10402A CR 10402 A CR10402 A CR 10402A CR 10402 A CR10402 A CR 10402A CR 10402 A CR10402 A CR 10402A
- Authority
- CR
- Costa Rica
- Prior art keywords
- compounds
- inhibitors
- beta
- formula
- methods
- Prior art date
Links
- 101710088194 Dehydrogenase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000001145 Metabolic Syndrome Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/50—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La presente invencion describe nuevos compuestos de formula I que tienen actividad antagonista de 11B-HSD tipo 1, asi como tambien metodos para preparar tales compuestos. En otra modalidad, la invencion describe composiciones farmaceuticas que comprenden compuestos de Formula I, asi como tambien metodos para usar los compuestos y composiciones para tratar diabetes, hipeglicemia, obesidad, hipertension, hiperlipidemia, sindrome metabolico, y otras condiciones asociadas con la actividad de 11B-HSD tipo 1.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74547506P | 2006-04-24 | 2006-04-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR10402A true CR10402A (es) | 2009-07-13 |
Family
ID=38564359
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR10402A CR10402A (es) | 2006-04-24 | 2008-10-24 | Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1 |
CR10401A CR10401A (es) | 2006-04-24 | 2008-10-24 | Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR10401A CR10401A (es) | 2006-04-24 | 2008-10-24 | Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1 |
Country Status (33)
Country | Link |
---|---|
US (1) | US8153807B2 (es) |
EP (1) | EP2021336B1 (es) |
JP (1) | JP5269765B2 (es) |
KR (1) | KR101059614B1 (es) |
CN (1) | CN101432275B (es) |
AT (1) | ATE472542T1 (es) |
AU (1) | AU2007244955B2 (es) |
BR (1) | BRPI0710467A2 (es) |
CA (1) | CA2646624C (es) |
CO (1) | CO6140034A2 (es) |
CR (2) | CR10402A (es) |
CY (1) | CY1110753T1 (es) |
DE (1) | DE602007007473D1 (es) |
DK (1) | DK2021336T3 (es) |
EA (1) | EA015106B1 (es) |
EC (1) | ECSP088833A (es) |
ES (1) | ES2345792T3 (es) |
HK (1) | HK1126208A1 (es) |
HR (1) | HRP20100397T1 (es) |
IL (1) | IL194810A (es) |
MA (1) | MA30686B1 (es) |
MX (1) | MX2008013649A (es) |
MY (1) | MY148079A (es) |
NO (1) | NO20084318L (es) |
NZ (1) | NZ571176A (es) |
PL (1) | PL2021336T3 (es) |
PT (1) | PT2021336E (es) |
RS (1) | RS51450B (es) |
SI (1) | SI2021336T1 (es) |
TN (1) | TNSN08417A1 (es) |
UA (1) | UA94741C2 (es) |
WO (1) | WO2007127688A2 (es) |
ZA (1) | ZA200808687B (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY148128A (en) * | 2006-04-21 | 2013-02-28 | Lilly Co Eli | Cyclohexylpyrazole-lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
JP5236628B2 (ja) | 2006-04-21 | 2013-07-17 | イーライ リリー アンド カンパニー | 11−β−ヒドロキシステロイドデヒドロゲナーゼ1阻害剤としての、シクロヘキシルイミダゾールラクタム誘導体 |
WO2007124337A1 (en) | 2006-04-21 | 2007-11-01 | Eli Lilly And Company | Biphenyl amide lactam derivatives as inhibitors of 11- beta-hydroxysteroid dehydrogenase 1 |
AU2007244960B2 (en) | 2006-04-24 | 2012-03-01 | Eli Lilly And Company | Substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
EP2049475B1 (en) | 2006-04-24 | 2012-02-01 | Eli Lilly & Company | Cyclohexyl substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
MX2008013651A (es) | 2006-04-25 | 2008-11-04 | Lilly Co Eli | Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1. |
WO2007127763A2 (en) | 2006-04-25 | 2007-11-08 | Eli Lilly And Company | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
JP5101602B2 (ja) | 2006-04-25 | 2012-12-19 | イーライ リリー アンド カンパニー | 11−β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤 |
PL2049513T3 (pl) * | 2006-04-28 | 2012-06-29 | Lilly Co Eli | Pirolidynony podstawione przez piperydynyl jako inhibitory dehydrogenazy 11-beta-hydroksysteroidowej typu 1 |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
EP2243479A3 (en) | 2009-04-20 | 2011-01-19 | Abbott Laboratories | Novel amide and amidine derivates and uses thereof |
US8871208B2 (en) * | 2009-12-04 | 2014-10-28 | Abbvie Inc. | 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and uses thereof |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8933024B2 (en) | 2010-06-18 | 2015-01-13 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
EP3235813A1 (en) | 2016-04-19 | 2017-10-25 | Cidqo 2012, S.L. | Aza-tetra-cyclo derivatives |
US11396493B2 (en) * | 2017-12-21 | 2022-07-26 | Guangdong Raynovent Biotech Co., Ltd. | Amorphous pyrrolidine derivative as PPAR agonist and preparation method thereof |
CN110483514B (zh) * | 2019-09-16 | 2022-06-14 | 启元生物(杭州)有限公司 | 一种氰基取代的环肼衍生物及其应用 |
CN110724142B (zh) * | 2019-10-29 | 2022-09-02 | 启元生物(杭州)有限公司 | 一种作为jak激酶抑制剂的酰胺或磺酰胺取代的肼衍生物 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004056744A1 (en) * | 2002-12-23 | 2004-07-08 | Janssen Pharmaceutica N.V. | Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors |
ATE397586T1 (de) * | 2004-05-07 | 2008-06-15 | Janssen Pharmaceutica Nv | Adamantyl pyrrolidin-2-on-derivate als 11-beta hydroxysteroid dehydrogenas inhibitoren |
MXPA06012932A (es) | 2004-05-07 | 2007-01-26 | Janssen Pharmaceutica Nv | Derivados de pirrolidin-2-ona y piperidin-2-ona como inhibidores de 11-beta hidroxiesteroide deshidrogenasa. |
JP2008515956A (ja) | 2004-10-12 | 2008-05-15 | ノボ ノルディスク アクティーゼルスカブ | 11β−ヒドロキシステロイドデヒドロゲナーゼ1型活性スピロ化合物 |
ATE419848T1 (de) | 2004-10-29 | 2009-01-15 | Lilly Co Eli | Cycloalkyl-lactam-derivate als inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1 |
GEP20125565B (en) | 2004-11-10 | 2012-07-10 | Incyte Corp | Lactam compounds and their pharmaceutical use |
DE602005007934D1 (de) * | 2004-12-20 | 2008-08-14 | Lilly Co Eli | Cycloalkyl-lactam-derivate als inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1 |
ES2308601T3 (es) | 2004-12-21 | 2008-12-01 | Eli Lilly And Company | Derivados de cicloalquil-lactama como inhibidores del 11-beta-hidroxiesteroide deshidrogenasa 1'. |
US20090264650A1 (en) | 2005-03-31 | 2009-10-22 | Nobuo Cho | Prophylactic/Therapeutic Agent for Diabetes |
WO2007066921A1 (en) * | 2005-12-08 | 2007-06-14 | Ho Young Lee | Structure of sticking extraneous matter and warm foot digital compression plate |
WO2007084314A2 (en) | 2006-01-12 | 2007-07-26 | Incyte Corporation | MODULATORS OF 11-ß HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME |
WO2007124337A1 (en) | 2006-04-21 | 2007-11-01 | Eli Lilly And Company | Biphenyl amide lactam derivatives as inhibitors of 11- beta-hydroxysteroid dehydrogenase 1 |
MY148128A (en) | 2006-04-21 | 2013-02-28 | Lilly Co Eli | Cyclohexylpyrazole-lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
JP5236628B2 (ja) | 2006-04-21 | 2013-07-17 | イーライ リリー アンド カンパニー | 11−β−ヒドロキシステロイドデヒドロゲナーゼ1阻害剤としての、シクロヘキシルイミダゾールラクタム誘導体 |
EP2049475B1 (en) | 2006-04-24 | 2012-02-01 | Eli Lilly & Company | Cyclohexyl substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
AU2007244960B2 (en) | 2006-04-24 | 2012-03-01 | Eli Lilly And Company | Substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
MX2008013651A (es) | 2006-04-25 | 2008-11-04 | Lilly Co Eli | Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1. |
JP5101602B2 (ja) | 2006-04-25 | 2012-12-19 | イーライ リリー アンド カンパニー | 11−β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤 |
WO2007127763A2 (en) | 2006-04-25 | 2007-11-08 | Eli Lilly And Company | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
PL2049513T3 (pl) | 2006-04-28 | 2012-06-29 | Lilly Co Eli | Pirolidynony podstawione przez piperydynyl jako inhibitory dehydrogenazy 11-beta-hydroksysteroidowej typu 1 |
US20090008890A1 (en) * | 2007-06-13 | 2009-01-08 | Woodford James R | Suspension system for an all-terrain vehicle |
CL2008001839A1 (es) | 2007-06-21 | 2009-01-16 | Incyte Holdings Corp | Compuestos derivados de 2,7-diazaespirociclos, inhibidores de 11-beta hidroxil esteroide deshidrogenasa tipo 1; composicion farmaceutica que comprende a dichos compuestos; utiles para tratar la obesidad, diabetes, intolerancia a la glucosa, diabetes tipo ii, entre otras enfermedades. |
US8871208B2 (en) * | 2009-12-04 | 2014-10-28 | Abbvie Inc. | 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and uses thereof |
-
2007
- 2007-04-23 DK DK07761091.3T patent/DK2021336T3/da active
- 2007-04-23 BR BRPI0710467-7A patent/BRPI0710467A2/pt not_active IP Right Cessation
- 2007-04-23 KR KR1020087025921A patent/KR101059614B1/ko not_active IP Right Cessation
- 2007-04-23 EP EP07761091A patent/EP2021336B1/en active Active
- 2007-04-23 EA EA200870470A patent/EA015106B1/ru not_active IP Right Cessation
- 2007-04-23 CN CN2007800149090A patent/CN101432275B/zh not_active Expired - Fee Related
- 2007-04-23 PL PL07761091T patent/PL2021336T3/pl unknown
- 2007-04-23 JP JP2009507912A patent/JP5269765B2/ja not_active Expired - Fee Related
- 2007-04-23 US US12/297,873 patent/US8153807B2/en not_active Expired - Fee Related
- 2007-04-23 MY MYPI20084249A patent/MY148079A/en unknown
- 2007-04-23 CA CA2646624A patent/CA2646624C/en not_active Expired - Fee Related
- 2007-04-23 SI SI200730353T patent/SI2021336T1/sl unknown
- 2007-04-23 DE DE602007007473T patent/DE602007007473D1/de active Active
- 2007-04-23 MX MX2008013649A patent/MX2008013649A/es active IP Right Grant
- 2007-04-23 PT PT07761091T patent/PT2021336E/pt unknown
- 2007-04-23 ES ES07761091T patent/ES2345792T3/es active Active
- 2007-04-23 UA UAA200812287A patent/UA94741C2/ru unknown
- 2007-04-23 WO PCT/US2007/067182 patent/WO2007127688A2/en active Application Filing
- 2007-04-23 AT AT07761091T patent/ATE472542T1/de active
- 2007-04-23 AU AU2007244955A patent/AU2007244955B2/en not_active Ceased
- 2007-04-23 RS RSP-2010/0399A patent/RS51450B/en unknown
- 2007-04-23 NZ NZ571176A patent/NZ571176A/en not_active IP Right Cessation
-
2008
- 2008-10-10 ZA ZA200808687A patent/ZA200808687B/xx unknown
- 2008-10-15 NO NO20084318A patent/NO20084318L/no not_active Application Discontinuation
- 2008-10-17 CO CO08110817A patent/CO6140034A2/es unknown
- 2008-10-17 EC EC2008008833A patent/ECSP088833A/es unknown
- 2008-10-20 TN TNP2008000417A patent/TNSN08417A1/en unknown
- 2008-10-22 IL IL194810A patent/IL194810A/en active IP Right Grant
- 2008-10-24 CR CR10402A patent/CR10402A/es unknown
- 2008-10-24 CR CR10401A patent/CR10401A/es not_active Application Discontinuation
- 2008-11-20 MA MA31398A patent/MA30686B1/fr unknown
-
2009
- 2009-05-25 HK HK09104719.3A patent/HK1126208A1/xx not_active IP Right Cessation
-
2010
- 2010-07-20 HR HR20100397T patent/HRP20100397T1/hr unknown
- 2010-08-30 CY CY20101100792T patent/CY1110753T1/el unknown
Also Published As
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