CO6280567A2 - Establecimiento de un anticuerpo monoclonal para detector de proteinas pag en la circulacion - Google Patents

Establecimiento de un anticuerpo monoclonal para detector de proteinas pag en la circulacion

Info

Publication number
CO6280567A2
CO6280567A2 CO10085345A CO10085345A CO6280567A2 CO 6280567 A2 CO6280567 A2 CO 6280567A2 CO 10085345 A CO10085345 A CO 10085345A CO 10085345 A CO10085345 A CO 10085345A CO 6280567 A2 CO6280567 A2 CO 6280567A2
Authority
CO
Colombia
Prior art keywords
establishment
circulation
monoclonal antibody
pag
protein detector
Prior art date
Application number
CO10085345A
Other languages
English (en)
Inventor
Nagappan Mathialagan
Michael Roberts
Jonathan Green
Michael F Mcgrath
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Publication of CO6280567A2 publication Critical patent/CO6280567A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/471—Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Se describen anticuerpos y métodos para detectar el embarazo en un animal: en ciertos aspectos, los anticuerpos utilizados se unen inmunológicamente al menos a dos PAGs seleccionadas de PAG PAG4, PAG6, PAG9, PAG16, PAG17, PAG19, PAG20 y PAG21; también se proveen los ácidos nucleicos que codifican el anticuerpo, así como los kits, métodos de uso y composiciones adicionales relacionadas con el anticuerpo.
CO10085345A 2007-12-13 2010-07-13 Establecimiento de un anticuerpo monoclonal para detector de proteinas pag en la circulacion CO6280567A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1360307P 2007-12-13 2007-12-13

Publications (1)

Publication Number Publication Date
CO6280567A2 true CO6280567A2 (es) 2011-05-20

Family

ID=40427459

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10085345A CO6280567A2 (es) 2007-12-13 2010-07-13 Establecimiento de un anticuerpo monoclonal para detector de proteinas pag en la circulacion

Country Status (16)

Country Link
US (1) US8431349B2 (es)
EP (1) EP2225274B1 (es)
JP (1) JP5679818B2 (es)
KR (1) KR101637613B1 (es)
CN (1) CN101918445B (es)
AU (1) AU2008334976B2 (es)
BR (1) BRPI0820885B8 (es)
CA (1) CA2709305C (es)
CO (1) CO6280567A2 (es)
DK (1) DK2225274T3 (es)
ES (1) ES2623459T3 (es)
HK (1) HK1148760A1 (es)
HU (1) HUE034401T2 (es)
NZ (1) NZ586100A (es)
WO (1) WO2009076632A1 (es)
ZA (1) ZA201004487B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009126889A1 (en) * 2008-04-10 2009-10-15 The Curators Of The University Of Missouri Assays for detecting pregnancy- associated glycoproteins
US8541187B2 (en) 2011-03-01 2013-09-24 Bio Tracking, LLC Systems and methods for detecting animal pregnancy
US9241977B2 (en) * 2013-03-01 2016-01-26 Arthrex, Inc. Enhanced anabolic cytokine production and delivery system
CN105424937B (zh) * 2015-10-05 2017-11-21 华中农业大学 一种猴早期妊娠检测的孕酮胶体金免疫层析试纸条
CN107219368B (zh) * 2017-06-06 2019-02-26 山西农业大学 奶牛pag1检测试纸条及其制备方法
CN107853241A (zh) * 2017-10-16 2018-03-30 广西壮族自治区水牛研究所 一种提高水牛配种效率的方法
KR102189893B1 (ko) * 2017-11-15 2020-12-11 (주)에스엘에스바이오 bPAG1에 특이적으로 결합하는 항체 및 이의 용도
CN108314732A (zh) * 2018-01-15 2018-07-24 妊达（北京）生物技术有限公司 一种抗牛早孕因子单克隆抗体细胞株单克隆抗体的制备方法
CN109295003B (zh) * 2018-09-10 2022-03-04 吉林医药学院 产生牛妊娠相关糖蛋白特异性单克隆抗体的小鼠杂交瘤细胞株、单克隆抗体、试剂盒及检测
CN111500583B (zh) * 2020-03-04 2021-09-10 新疆农垦科学院 特异性识别牛妊娠相关糖蛋白4的核酸适配体及其应用
CN113960025A (zh) * 2021-10-12 2022-01-21 北京农学院 一种奶牛早期妊娠的检测方法
KR20230065047A (ko) * 2021-11-04 2023-05-11 주식회사 나노바이오라이프 소 임신 진단 항체와 이를 이용한 조기 임신 진단키트 개발
CN114672464A (zh) * 2022-03-31 2022-06-28 吴峰 一种分泌抗牛妊娠相关糖蛋白单克隆抗体的杂交瘤细胞、单克隆抗体及应用

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
US4208479A (en) 1977-07-14 1980-06-17 Syva Company Label modified immunoassays
US4271140A (en) 1978-01-23 1981-06-02 Baxter Travenol Laboratories, Inc. Method and composition for double receptor, specific binding assays
US4895804A (en) 1984-07-06 1990-01-23 University Of Minnesota Bovine antigen glycoprotein, related antibody, and use in detection of pregnancy in cattle
US4755460A (en) 1984-07-06 1988-07-05 The Regents Of The Univ. Of Minnesota Bovine antigen glycoprotein, related antibody, and use in detection of pregnancy in cattle
DE3682088D1 (de) * 1985-03-18 1991-11-28 Mitsubishi Petrochemical Co Verfahren zur herstellung von wasserabsorbierenden polymeren.
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
DE19733505A1 (de) 1997-08-01 1999-02-04 Knoll Ag Schnell wirksames Analgeticum
CN1296567A (zh) 1998-02-02 2001-05-23 康瑟普托诊断公司 用于检测动物怀孕的方法和装置
CA2323812C (en) 1998-03-20 2011-05-10 The Curators Of The University Of Missouri Early pregnancy diagnosis using pags (pregnancy-associated glycoproteins)
BR0210474A (pt) * 2001-06-19 2004-08-10 Idaho Res Foundation Determinação do estado de prenhez
NZ531818A (en) * 2001-09-25 2005-10-28 Fujisawa Pharmaceutical Co Recombinant anti-osteopontin antibody and use in the treatment of autoimmune diseases such as rheumatoid arthritis and osteoarthritis
US7393696B2 (en) 2001-09-28 2008-07-01 Aspenbio Pharma, Inc. Bovine pregnancy test
EP1468288A4 (en) 2001-11-20 2006-03-15 Univ Missouri COMPOSITIONS AND METHODS FOR PRECISE PRECISE DIAGNOSIS OF PREGNANCY
EP1796495A2 (en) * 2004-09-29 2007-06-20 Koninklijke Philips Electronics N.V. Smart handbag
WO2009126889A1 (en) 2008-04-10 2009-10-15 The Curators Of The University Of Missouri Assays for detecting pregnancy- associated glycoproteins

Also Published As

Publication number Publication date
BRPI0820885B8 (pt) 2021-03-02
JP5679818B2 (ja) 2015-03-04
HK1148760A1 (en) 2011-09-16
JP2011507810A (ja) 2011-03-10
CA2709305C (en) 2017-03-07
WO2009076632A1 (en) 2009-06-18
ES2623459T3 (es) 2017-07-11
DK2225274T3 (en) 2017-05-01
EP2225274A1 (en) 2010-09-08
EP2225274B1 (en) 2017-02-15
ZA201004487B (en) 2011-04-28
HUE034401T2 (en) 2018-02-28
KR20100110818A (ko) 2010-10-13
AU2008334976A1 (en) 2009-06-18
CA2709305A1 (en) 2009-06-18
CN101918445B (zh) 2014-05-14
NZ586100A (en) 2012-07-27
CN101918445A (zh) 2010-12-15
US20110076705A1 (en) 2011-03-31
BRPI0820885A2 (pt) 2015-07-21
US8431349B2 (en) 2013-04-30
AU2008334976B2 (en) 2013-05-23
KR101637613B1 (ko) 2016-07-07

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