CO5261593A1 - Formulaciones de entecavir de dosis bajas y uso - Google Patents
Formulaciones de entecavir de dosis bajas y usoInfo
- Publication number
- CO5261593A1 CO5261593A1 CO01015910A CO01015910A CO5261593A1 CO 5261593 A1 CO5261593 A1 CO 5261593A1 CO 01015910 A CO01015910 A CO 01015910A CO 01015910 A CO01015910 A CO 01015910A CO 5261593 A1 CO5261593 A1 CO 5261593A1
- Authority
- CO
- Colombia
- Prior art keywords
- carrier substrate
- pharmaceutical composition
- low dose
- solvent
- active agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Una composición farmacéutica para administración una vez al día para tratar la infección del virus de la hepatitis B, caracterizada porque comprende un portador farmacéuticamente aceptable y desde aproximadamente 0.001 hasta aproximadamente 25 mg de entecavir.2El método de preparación de una composición farmacéutica para la administración oral que contiene una dosis baja de un agente farmacéuticamente activo soluble caracterizado porque comprende:(a) disolver dicho agente farmacéuticamente activo y una substancia adhesiva en un solvente,(b) rociar dicha solución de la etapa (a) en un substrato portador, mientras dicho substrato portador está en movimiento,(c) secar dicho substrato portador revestido de la etapa (b) para remover dicho solvente, y(d) combinar dicho substrato portador revestido secado de la etapa (c) con otros ingredientes deseados para formar dicha composición farmacéutica.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18567200P | 2000-02-29 | 2000-02-29 | |
US22131300P | 2000-07-28 | 2000-07-28 | |
PCT/US2001/002630 WO2001064221A1 (en) | 2000-02-29 | 2001-01-26 | Low dose entecavir formulation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5261593A1 true CO5261593A1 (es) | 2003-03-31 |
Family
ID=26881354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO01015910A CO5261593A1 (es) | 2000-02-29 | 2001-02-28 | Formulaciones de entecavir de dosis bajas y uso |
Country Status (35)
Country | Link |
---|---|
US (1) | US6627224B2 (es) |
EP (2) | EP1267880B2 (es) |
JP (3) | JP5140222B2 (es) |
KR (1) | KR100757155B1 (es) |
AR (1) | AR027965A1 (es) |
AT (1) | ATE312613T1 (es) |
AU (1) | AU2001229775A1 (es) |
BG (1) | BG65815B1 (es) |
BR (1) | BRPI0108435B8 (es) |
CA (1) | CA2401569C (es) |
CO (1) | CO5261593A1 (es) |
CZ (1) | CZ303395B6 (es) |
DE (1) | DE60115870T3 (es) |
DK (1) | DK1267880T4 (es) |
EA (1) | EA006181B1 (es) |
EE (1) | EE05442B1 (es) |
EG (1) | EG24408A (es) |
ES (1) | ES2253403T5 (es) |
GE (1) | GEP20053504B (es) |
HK (1) | HK1048771A1 (es) |
HR (1) | HRP20020649A2 (es) |
HU (1) | HU230698B1 (es) |
IL (1) | IL150447A0 (es) |
MX (1) | MXPA02008359A (es) |
MY (1) | MY127422A (es) |
NO (1) | NO324014B1 (es) |
NZ (1) | NZ520024A (es) |
PE (1) | PE20020770A1 (es) |
PL (1) | PL201411B1 (es) |
RS (1) | RS51561B (es) |
SI (1) | SI1267880T2 (es) |
SK (1) | SK288008B6 (es) |
TW (1) | TWI287988B (es) |
UA (1) | UA84534C2 (es) |
WO (1) | WO2001064221A1 (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU230698B1 (hu) * | 2000-02-29 | 2017-09-28 | Bristol-Myers Squibb Holdings Ireland | Alacsony dózisú entecavir formuláció és alkalmazása |
TWI275392B (en) * | 2002-04-08 | 2007-03-11 | Bristol Myers Squibb Co | Low dose liquid entecavir formulations and use |
AR040588A1 (es) | 2002-07-26 | 2005-04-13 | Schering Corp | Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa |
PL212790B1 (pl) | 2002-12-11 | 2012-11-30 | Bristol Myers Squibb Co | Sposób wytwarzania entekawiru, produkty posrednie, sposób wytwarzania produktu posredniego oraz pochodna metanosulfonianowa |
US20040224917A1 (en) | 2003-01-14 | 2004-11-11 | Gilead Sciences, Inc. | Compositions and methods for combination antiviral therapy |
DK1708690T3 (en) | 2003-11-17 | 2016-11-07 | Biomarin Pharm Inc | TREATMENT OF PHENYLKETONURI WITH BH4 |
KR20060125805A (ko) * | 2003-11-18 | 2006-12-06 | 베링거 인겔하임 인터내셔날 게엠베하 | 고체 약제학적 제제 형태 |
US7511139B2 (en) * | 2004-06-04 | 2009-03-31 | Bristol-Myers Squibb Company | Process for the preparation of entecavir and novel intermediates thereof via carbon-silicon oxidation |
JP4756153B2 (ja) * | 2004-08-27 | 2011-08-24 | 富士製薬工業株式会社 | 低成分含量の錠剤の製造方法 |
US20060127451A1 (en) * | 2004-09-23 | 2006-06-15 | Michael Augello | Coating composition |
TWI375560B (en) | 2005-06-13 | 2012-11-01 | Gilead Sciences Inc | Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same |
TWI471145B (zh) | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
CN101245068A (zh) * | 2007-02-14 | 2008-08-20 | 浙江医药股份有限公司新昌制药厂 | 结晶型态的恩替卡韦及其制备方法和其药物组合物及用途 |
TW200904405A (en) | 2007-03-22 | 2009-02-01 | Bristol Myers Squibb Co | Pharmaceutical formulations containing an SGLT2 inhibitor |
CA2778273A1 (en) | 2009-10-28 | 2011-05-12 | Mcneil-Ppc, Inc. | Fast dissolving/disintegrating coating compositions |
DE102009060194A1 (de) | 2009-12-23 | 2011-06-30 | ratiopharm GmbH, 89079 | Orale Darreichungsform umfassend Entecavir |
WO2011076412A1 (de) | 2009-12-23 | 2011-06-30 | Ratiopharm Gmbh | Orale darreichungsform umfassend entecavir |
US9168269B2 (en) | 2010-02-18 | 2015-10-27 | The Trustees Of Princeton University | Inhibitors of long and very long chain fatty acid metabolism as broad spectrum anti-virals |
NZ602622A (en) | 2010-03-31 | 2015-01-30 | Millennium Pharm Inc | Derivatives of 1-amino-2-cyclopropylethylboronic acid |
WO2012048455A1 (zh) * | 2010-10-12 | 2012-04-19 | 武汉大学 | 一种抗病毒透皮吸收贴片及其制备方法 |
EP2508172A1 (en) | 2011-04-06 | 2012-10-10 | Zentiva, a.s. | Stable and uniform formulations of entecavir and preparation method thereof |
KR101594820B1 (ko) * | 2011-06-16 | 2016-02-17 | 건일제약 주식회사 | 엔테카비르를 함유하는 미립구 및 이의 제조방법 |
WO2013066028A1 (ko) | 2011-11-01 | 2013-05-10 | 대원제약주식회사 | 안정성이 향상된 엔테카비어를 함유하는 약학적 조성물 및 그 제조방법 |
IN2011CH03893A (es) * | 2011-11-14 | 2015-08-21 | Hetero Research Foundation | |
EP2644197A1 (en) * | 2012-03-26 | 2013-10-02 | Sanovel Ilac Sanayi ve Ticaret A.S. | Novel Pharmaceutical Compositions of Entecavir |
EP2644196B1 (en) * | 2012-03-26 | 2019-09-18 | Arven Ilac Sanayi ve Ticaret A.S. | Pharmaceutical compositions of Entecavir |
KR101285008B1 (ko) * | 2012-04-18 | 2013-07-10 | 제일약품주식회사 | 저용량 엔테카비어의 경구투여 제제의 제조방법 |
CA2779052A1 (en) * | 2012-05-31 | 2013-11-30 | Pharmascience Inc. | Pharmaceutical composition of entecavir and process of manufacturing |
CN103908436B (zh) * | 2012-12-29 | 2016-02-10 | 安徽贝克生物制药有限公司 | 一种速释型恩替卡韦组合物 |
KR101512895B1 (ko) | 2013-08-09 | 2015-04-16 | 대화제약 주식회사 | 엔테카비어를 포함하는 약학적 조성물의 제조방법 |
CN106573003B (zh) * | 2014-06-20 | 2022-04-01 | 西梯茜生命工学股份有限公司 | 含有恩替卡韦作为活性成分的药物制剂及其制备方法 |
US11273129B2 (en) | 2015-09-30 | 2022-03-15 | Daicel Corporation | Particle composition for easy-to-use solid preparation and easy-to-use solid preparation including said particle composition |
KR20230112817A (ko) | 2022-01-21 | 2023-07-28 | 한림대학교 산학협력단 | 피루브산 및 pdk 억제제를 포함하는 뇌질환의 예방 또는 치료용 조성물 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3836618A (en) * | 1971-12-23 | 1974-09-17 | American Home Prod | Process for the uniform distribution of a drug on a granulated base |
US4513008A (en) * | 1982-07-30 | 1985-04-23 | The Vinoxen Company, Inc. | Virucidal compositions and therapy |
US4489026A (en) * | 1982-09-07 | 1984-12-18 | The Upjohn Company | Process for preparing solid unit dosage forms of ultra-low dose drugs |
US4631284A (en) * | 1984-11-19 | 1986-12-23 | Mallinckrodt, Inc. | Acetaminophen compositions containing low doses of chlorpheniramine maleate, method for preparing same and tablets formed therefrom |
US5206244A (en) | 1990-10-18 | 1993-04-27 | E. R. Squibb & Sons, Inc. | Hydroxymethyl (methylenecyclopentyl) purines and pyrimidines |
JPH08208478A (ja) * | 1994-10-14 | 1996-08-13 | Japan Energy Corp | 抗エイズ薬製剤およびその製造方法 |
ATE243500T1 (de) * | 1996-04-04 | 2003-07-15 | Felix Specht | Verfahren zur herstellung von gering dosierten freifliessenden und/oder direktkomprimierbaren pulversystemen |
AU4090697A (en) | 1996-09-03 | 1998-03-26 | Bristol-Myers Squibb Company | Improved process for preparing the antiviral agent {1s-(1alpha, 3alpha, 4beta)}-2-amino-1,9-dihydro-9-{4-hydroxy-3-(hydroxymethyl)-2 -methylenecyclopentyl}-6h-purin-6-one |
ES2579903T3 (es) * | 1998-08-10 | 2016-08-17 | Centre National De La Recherche Scientifique (Cnrs) | Beta-L-2'-desoxi-nucleósidos para el tratamiento de la hepatitis B |
US5997905A (en) * | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
GB9820417D0 (en) | 1998-09-18 | 1998-11-11 | Glaxo Group Ltd | Antiviral combinations |
GB9820416D0 (en) | 1998-09-18 | 1998-11-11 | Glaxo Group Ltd | Antiviral combinations |
GB9820420D0 (en) | 1998-09-18 | 1998-11-11 | Glaxo Group Ltd | Antiviral combinations |
US6432966B2 (en) * | 1999-10-29 | 2002-08-13 | Smithkline Beecham Corporation | Antiviral combinations |
HU230698B1 (hu) * | 2000-02-29 | 2017-09-28 | Bristol-Myers Squibb Holdings Ireland | Alacsony dózisú entecavir formuláció és alkalmazása |
-
2001
- 2001-01-26 HU HU0500558A patent/HU230698B1/hu unknown
- 2001-01-26 NZ NZ520024A patent/NZ520024A/en not_active IP Right Cessation
- 2001-01-26 UA UA2002097732A patent/UA84534C2/uk unknown
- 2001-01-26 BR BR0108435-6 patent/BRPI0108435B8/pt not_active IP Right Cessation
- 2001-01-26 ES ES01955090T patent/ES2253403T5/es not_active Expired - Lifetime
- 2001-01-26 MX MXPA02008359A patent/MXPA02008359A/es active IP Right Grant
- 2001-01-26 AT AT01955090T patent/ATE312613T1/de active
- 2001-01-26 DE DE60115870T patent/DE60115870T3/de not_active Expired - Lifetime
- 2001-01-26 EE EEP200200484A patent/EE05442B1/xx unknown
- 2001-01-26 RS YU63002A patent/RS51561B/sr unknown
- 2001-01-26 DK DK01955090.4T patent/DK1267880T4/da active
- 2001-01-26 GE GE4868A patent/GEP20053504B/en unknown
- 2001-01-26 PL PL366102A patent/PL201411B1/pl unknown
- 2001-01-26 IL IL15044701A patent/IL150447A0/xx active IP Right Grant
- 2001-01-26 EP EP01955090A patent/EP1267880B2/en not_active Expired - Lifetime
- 2001-01-26 EP EP05020938A patent/EP1642582A1/en not_active Withdrawn
- 2001-01-26 AU AU2001229775A patent/AU2001229775A1/en not_active Abandoned
- 2001-01-26 WO PCT/US2001/002630 patent/WO2001064221A1/en active IP Right Grant
- 2001-01-26 CZ CZ20022902A patent/CZ303395B6/cs not_active IP Right Cessation
- 2001-01-26 SI SI200130502T patent/SI1267880T2/sl unknown
- 2001-01-26 KR KR1020027011143A patent/KR100757155B1/ko active IP Right Review Request
- 2001-01-26 JP JP2001563118A patent/JP5140222B2/ja not_active Expired - Lifetime
- 2001-01-26 CA CA002401569A patent/CA2401569C/en not_active Expired - Lifetime
- 2001-01-26 SK SK1165-2002A patent/SK288008B6/sk not_active IP Right Cessation
- 2001-01-26 EA EA200200812A patent/EA006181B1/ru not_active IP Right Cessation
- 2001-02-07 MY MYPI20010532A patent/MY127422A/en unknown
- 2001-02-22 TW TW090104020A patent/TWI287988B/zh not_active IP Right Cessation
- 2001-02-23 US US09/792,576 patent/US6627224B2/en not_active Expired - Lifetime
- 2001-02-26 EG EG20010191A patent/EG24408A/xx active
- 2001-02-28 CO CO01015910A patent/CO5261593A1/es not_active Application Discontinuation
- 2001-02-28 AR ARP010100961A patent/AR027965A1/es not_active Application Discontinuation
- 2001-06-12 PE PE2001000552A patent/PE20020770A1/es not_active Application Discontinuation
-
2002
- 2002-07-05 BG BG106905A patent/BG65815B1/bg unknown
- 2002-08-01 HR HRP20020649 patent/HRP20020649A2/hr not_active Application Discontinuation
- 2002-08-28 NO NO20024099A patent/NO324014B1/no not_active IP Right Cessation
-
2003
- 2003-02-14 HK HK03101080.6A patent/HK1048771A1/zh unknown
-
2012
- 2012-08-22 JP JP2012183484A patent/JP2012255017A/ja not_active Revoked
-
2015
- 2015-05-27 JP JP2015107778A patent/JP5921746B2/ja not_active Expired - Lifetime
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