CO4790156A1 - Polipeptidos de membrana de linfocito de mamifero y acidos nucleicos que los codifican - Google Patents
Polipeptidos de membrana de linfocito de mamifero y acidos nucleicos que los codificanInfo
- Publication number
- CO4790156A1 CO4790156A1 CO98038990A CO98038990A CO4790156A1 CO 4790156 A1 CO4790156 A1 CO 4790156A1 CO 98038990 A CO98038990 A CO 98038990A CO 98038990 A CO98038990 A CO 98038990A CO 4790156 A1 CO4790156 A1 CO 4790156A1
- Authority
- CO
- Colombia
- Prior art keywords
- seq
- gly
- residues
- cys
- gln
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/7056—Lectin superfamily, e.g. CD23, CD72
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se describen ácidos nucleicos que codifican varias proteínas decélulas de linfocitos de mamíferos que incluyen primates, los reactivos relacionados con los mismos, incluyendo los anticuerpos específicos, y proteínas purificadas. También se proveen métodos para usar dichos reactivos y equipos de diagnóstico relacionados. Un polipéptido DCMP1 recombinante o sustancialmente puro que exhibe por lo menos una secuencia de identidad de 85% con la SEC ID N°: 2 u 8. Un polipéptido DCMP2 recombinante sustancialmente puro que comprende: a) un polipéptido seleccionado de: 1) Gly Val Ser Glu Leu Gln Glu His Thr Thr Gln Lys Ala His Leu Gly His Cys Pro His Cys Pro Ser Val Cys Val Pro (residuos 118-144 de SEC ID No: 4); 2) Gln Val Ala Thr Leu Asn Asn Asn Ala Ser Thr Glu Gly Thr Cys Cys (residuos 116-181 de SEC ID N°: 4); o 3) Trp Lys Pro Gly Gln Pro Asp Asn Trp Gln Gly His Gly Leu Gly (residuos 263-277 de SEC ID No: 4); o b) Secuencia que exhibe ambas: 1) por lo menos 17 aminoácidos contiguos de DCMP2v tal como se describió en SEC ID N°: 10; y 2) una falta de un segmento de por lo menos 12 aminoácidos contiguos de FKNGPLPLQS LLQRLRWGPC HLLLWLGLGL LLVIIC (residuos 20-56 de SEC ID N°: 4). Las células huésped apropiadas incluyen procariotos, eucariotos inferiores y eucariotos superiores. Los procariotos incluyen los organismos gram negativos y gram positivos, por ejemplo, E. Coli y B. Subtilis. Los eucariotos inferiores incluyen levaduras, por ejemplo S. Verevisiae y Pichia, y especies de los géneros Dictyostelium. Los eucariotos superiores incluyen líneas de células de cultivos de tejidos establecidos a partir de células animales tanto de origen no mamífero como por ejemplo células de insectos y aves como origen de mamífero por ejemplo de seres humanos primates y roedores. ..
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5308097P | 1997-07-09 | 1997-07-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO4790156A1 true CO4790156A1 (es) | 1999-05-31 |
Family
ID=21981809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO98038990A CO4790156A1 (es) | 1997-07-09 | 1998-07-09 | Polipeptidos de membrana de linfocito de mamifero y acidos nucleicos que los codifican |
Country Status (24)
Country | Link |
---|---|
US (6) | US6277959B1 (es) |
EP (2) | EP0998496B1 (es) |
JP (2) | JP2002509438A (es) |
KR (1) | KR20010021597A (es) |
CN (2) | CN100391973C (es) |
AR (1) | AR014891A1 (es) |
AT (1) | ATE397018T1 (es) |
AU (1) | AU755279C (es) |
BR (1) | BR9811675A (es) |
CA (1) | CA2295308C (es) |
CO (1) | CO4790156A1 (es) |
DE (1) | DE69839555D1 (es) |
ES (1) | ES2308808T3 (es) |
HK (1) | HK1028249A1 (es) |
HU (1) | HUP0002472A3 (es) |
ID (1) | ID26517A (es) |
IL (1) | IL133494A0 (es) |
NO (1) | NO20000097L (es) |
NZ (1) | NZ501777A (es) |
PE (1) | PE96899A1 (es) |
PL (1) | PL337942A1 (es) |
SK (1) | SK252000A3 (es) |
WO (1) | WO1999002562A1 (es) |
ZA (1) | ZA986051B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040258688A1 (en) * | 1995-01-31 | 2004-12-23 | Daniel Hawiger | Enhanced antigen delivery and modulation of the immune response therefrom |
US20020187131A1 (en) * | 1995-01-31 | 2002-12-12 | Daniel Hawiger | Enhanced antigen delivery and modulation of the immune response therefrom |
AU3063699A (en) * | 1998-03-17 | 1999-10-11 | Schering Corporation | Isolated mammalian membrane protein genes and related reagents |
US7030228B1 (en) | 1999-11-15 | 2006-04-18 | Miltenyi Biotec Gmbh | Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby |
DK1301539T3 (da) * | 1999-11-15 | 2007-05-21 | Miltenyi Biotec Gmbh | Antigenbindende fragmenter, der er specifikke for dendristiske celler, sammensætninger og fremgangsmåder til anvendelse deraf, antigener, der genkendes deraf, og celler opnået derved |
US7560534B2 (en) | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
MXPA02010869A (es) | 2000-05-08 | 2003-04-14 | Medarex Inc | Anticuerpos monoclonales humanos para celulas dendriticas. |
EP1442046A4 (en) * | 2001-10-09 | 2005-08-31 | Immunex Corp | MAMMALIAN TYPE C LECTINES |
US20060008807A1 (en) * | 2002-08-23 | 2006-01-12 | O'hara Shawn M | Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample |
US9259459B2 (en) * | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
ATE552860T1 (de) * | 2003-01-31 | 2012-04-15 | Celldex Res Corp | Antikörper-vakzine-konjugate und ihre verwendungen |
US7547760B2 (en) * | 2006-07-03 | 2009-06-16 | West Virginia University | Peptides and chemical compound for inhibition of SHP2 function |
AU2014240262B2 (en) * | 2007-02-02 | 2016-04-28 | Baylor Research Institute | Agents that engage antigen - presenting cells through dendritic cell asialoglycoprotein receptor (dc-asgpr) |
TWI422594B (zh) | 2007-02-02 | 2014-01-11 | Baylor Res Inst | 經由樹狀細胞去唾液酸糖蛋白受體(dc-asgpr)接合抗原呈現細胞之藥劑 |
EP2115002B1 (en) * | 2007-02-02 | 2014-08-20 | Baylor Research Institute | Vaccines based on targeting antigen to dcir expressed an antigen-presenting cells |
NZ585556A (en) | 2007-11-07 | 2012-07-27 | Celldex Therapeutics Inc | Antibodies that bind human dendritic and epithelial cell 205 (dec-205) |
US20130058957A1 (en) * | 2010-02-23 | 2013-03-07 | The University Of Tokyo | Dendritic cell immunoreceptor agonist |
US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
CN106659774A (zh) | 2014-05-16 | 2017-05-10 | 贝勒研究院 | 用于治疗自身免疫和炎性病症的方法和组合物 |
CN108314740B (zh) * | 2018-03-07 | 2024-02-27 | 上海晶诺生物科技有限公司 | 一种蛋白固定化修饰的细胞培养容器 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1319315A (en) | 1969-06-19 | 1973-06-06 | Citizen Watch Co Ltd | Calendar timepiece |
US3940475A (en) | 1970-06-11 | 1976-02-24 | Biological Developments, Inc. | Radioimmune method of assaying quantitatively for a hapten |
NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
US4659678A (en) | 1982-09-29 | 1987-04-21 | Serono Diagnostics Limited | Immunoassay of antigens |
NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4859609A (en) | 1986-04-30 | 1989-08-22 | Genentech, Inc. | Novel receptors for efficient determination of ligands and their antagonists or agonists |
-
1998
- 1998-07-08 AT AT98932932T patent/ATE397018T1/de not_active IP Right Cessation
- 1998-07-08 AR ARP980103338A patent/AR014891A1/es unknown
- 1998-07-08 EP EP98932932A patent/EP0998496B1/en not_active Expired - Lifetime
- 1998-07-08 CN CNB988069679A patent/CN100391973C/zh not_active Expired - Fee Related
- 1998-07-08 CN CNA031082459A patent/CN1493597A/zh active Pending
- 1998-07-08 CA CA2295308A patent/CA2295308C/en not_active Expired - Fee Related
- 1998-07-08 KR KR1020007000155A patent/KR20010021597A/ko not_active Application Discontinuation
- 1998-07-08 HU HU0002472A patent/HUP0002472A3/hu unknown
- 1998-07-08 PL PL98337942A patent/PL337942A1/xx not_active Application Discontinuation
- 1998-07-08 IL IL13349498A patent/IL133494A0/xx unknown
- 1998-07-08 EP EP20080007647 patent/EP1980573A3/en not_active Ceased
- 1998-07-08 WO PCT/US1998/013436 patent/WO1999002562A1/en not_active Application Discontinuation
- 1998-07-08 BR BR9811675-4A patent/BR9811675A/pt not_active IP Right Cessation
- 1998-07-08 NZ NZ501777A patent/NZ501777A/en unknown
- 1998-07-08 SK SK25-2000A patent/SK252000A3/sk unknown
- 1998-07-08 US US09/111,470 patent/US6277959B1/en not_active Expired - Lifetime
- 1998-07-08 DE DE69839555T patent/DE69839555D1/de not_active Expired - Lifetime
- 1998-07-08 ZA ZA986051A patent/ZA986051B/xx unknown
- 1998-07-08 ES ES98932932T patent/ES2308808T3/es not_active Expired - Lifetime
- 1998-07-08 AU AU82712/98A patent/AU755279C/en not_active Ceased
- 1998-07-08 JP JP50871099A patent/JP2002509438A/ja active Pending
- 1998-07-08 ID IDW20000037A patent/ID26517A/id unknown
- 1998-07-09 CO CO98038990A patent/CO4790156A1/es unknown
- 1998-07-09 PE PE1998000608A patent/PE96899A1/es not_active Application Discontinuation
-
2000
- 2000-01-07 NO NO20000097A patent/NO20000097L/no not_active Application Discontinuation
- 2000-10-25 HK HK00106810A patent/HK1028249A1/xx not_active IP Right Cessation
-
2001
- 2001-05-22 US US09/862,802 patent/US6756478B2/en not_active Expired - Lifetime
-
2004
- 2004-04-21 US US10/829,107 patent/US7034137B2/en not_active Expired - Lifetime
-
2005
- 2005-09-20 US US11/230,749 patent/US7179467B2/en not_active Expired - Fee Related
-
2007
- 2007-01-05 US US11/620,440 patent/US7691373B2/en not_active Expired - Fee Related
-
2008
- 2008-06-26 JP JP2008167989A patent/JP2008264000A/ja active Pending
-
2010
- 2010-01-22 US US12/691,868 patent/US20110244513A1/en not_active Abandoned
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