CO2022001348A2 - Composiciones enzimáticas inmovilizadas para la producción de hexosas - Google Patents

Composiciones enzimáticas inmovilizadas para la producción de hexosas

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Publication number
CO2022001348A2
CO2022001348A2 CONC2022/0001348A CO2022001348A CO2022001348A2 CO 2022001348 A2 CO2022001348 A2 CO 2022001348A2 CO 2022001348 A CO2022001348 A CO 2022001348A CO 2022001348 A2 CO2022001348 A2 CO 2022001348A2
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CO
Colombia
Prior art keywords
immobilized enzyme
hexoses
production
enzyme compositions
hexose
Prior art date
Application number
CONC2022/0001348A
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English (en)
Inventor
Daniel Joseph Wichelecki
Jonathan Wagner
Original Assignee
Bonumose Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bonumose Inc filed Critical Bonumose Inc
Publication of CO2022001348A2 publication Critical patent/CO2022001348A2/es

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    • C12P19/02—Monosaccharides
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
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    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
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    • C12Y501/03015—Glucose-6-phosphate 1-epimerase (5.1.3.15)

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  • Chemical & Material Sciences (AREA)
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Abstract

La invención se refiere a composiciones de enzimas inmovilizadas para la preparación de una hexosa. Las hexosas incluyen, por ejemplo, tagatosa, psicosa, fructosa, alosa, manosa, galactosa, altrosa, talosa, sorbosa, gulosa, idosa e inositol. La invención también se refiere a un proceso enzimático para preparar una hexosa a partir de un sacárido poniendo en contacto un derivado de almidón con una composición enzimática inmovilizada de la invención.
CONC2022/0001348A 2019-07-17 2022-02-10 Composiciones enzimáticas inmovilizadas para la producción de hexosas CO2022001348A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962875321P 2019-07-17 2019-07-17
US201962924323P 2019-10-22 2019-10-22
PCT/US2020/042562 WO2021011881A1 (en) 2019-07-17 2020-07-17 Immobilized enzyme compositions for the production of hexoses

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CO2022001348A2 true CO2022001348A2 (es) 2022-05-20

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EP (1) EP3999636A4 (es)
JP (1) JP2022541471A (es)
KR (1) KR20220035460A (es)
CN (1) CN114599786A (es)
BR (1) BR112022000699A2 (es)
CA (1) CA3143852A1 (es)
CO (1) CO2022001348A2 (es)
MX (1) MX2022000381A (es)
WO (1) WO2021011881A1 (es)

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MX2023008520A (es) * 2021-02-02 2023-09-25 Bonumose Inc Enriquecimiento enzimático de ingredientes alimentarios para la reducción de azúcar.
CN112708614A (zh) * 2021-02-05 2021-04-27 江南大学 一种共固定化双酶的制备方法和应用
CN112760317B (zh) * 2021-04-07 2021-08-24 中国科学院天津工业生物技术研究所 仿生硅矿化微囊固定化多酶生产塔格糖的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2515340C (en) * 2003-03-06 2016-04-26 Diversa Corporation Amylases, nucleic acids encoding them and methods for making and using them
US20080148432A1 (en) * 2005-12-21 2008-06-19 Mark Scott Abad Transgenic plants with enhanced agronomic traits
EP1856291A4 (en) * 2005-03-04 2009-04-01 Verenium Corp NUCLEIC ACIDS AND PROTEINS, AND METHODS OF MAKING AND USING SAME
EP2048939A4 (en) * 2006-08-17 2010-04-28 Monsanto Technology Llc TRANSGENIC PLANTS WITH ADVANCED AGRONOMIC CHARACTERISTICS
EP2175714A4 (en) * 2007-07-10 2011-01-26 Monsanto Technology Llc TRANSGENIC PLANTS WITH IMPROVED AGRONOMIC CHARACTERISTICS
US10793848B2 (en) * 2014-01-31 2020-10-06 Enginzyme Ab Immobilized proteins and use thereof
MA46152B1 (fr) * 2016-12-14 2020-11-30 Bonumose Llc Production enzymatique de d-allulose
DE102017002252A1 (de) * 2017-03-08 2018-09-13 André Pick Enzymatisches Verfahren zur Herstellung von Fructose
RU2766710C2 (ru) * 2017-03-13 2022-03-15 Бонамоуз, Инк. Ферментативное получение гексоз
KR102074957B1 (ko) * 2017-03-31 2020-02-10 씨제이제일제당 주식회사 타가토스 생산용 조성물 및 이를 이용한 타가토스 제조방법
EP3867393A4 (en) * 2018-10-19 2022-08-24 Bonumose, Inc. ENZYMATIC PRODUCTION OF TAGATOSE
AU2019373147A1 (en) * 2018-10-29 2022-03-24 Bonumose Inc. Enzymatic production of hexoses
JP2022520791A (ja) * 2019-02-12 2022-04-01 ボヌモーズ、インコーポレイテッド マンノースの酵素的生産
CN112626060B (zh) * 2019-10-09 2022-05-13 中国科学院天津工业生物技术研究所 一种用于生产肌醇的固定化多酶体系以及生产肌醇的方法

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EP3999636A4 (en) 2023-09-20
CN114599786A (zh) 2022-06-07
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BR112022000699A2 (pt) 2022-03-03

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