US2776926A
(en)
|
1955-08-04 |
1957-01-08 |
Eugene S Sharpe |
Preparation of alpha-ketoglutaric acid by serratia marcescens
|
US2917528A
(en)
*
|
1956-08-24 |
1959-12-15 |
Victor Chemical Works |
Alkanolaminealkanephosphonic acids and salts thereof
|
US2841616A
(en)
*
|
1956-10-30 |
1958-07-01 |
Campbell Soup Co |
Process for the recovery of alpha-ketoglutaric acid
|
US3875304A
(en)
|
1970-04-24 |
1975-04-01 |
Schlitz Brewing Co J |
Livestock feed composition and method of preparing the same
|
US4045585A
(en)
|
1976-05-19 |
1977-08-30 |
Decel Corporation |
Flavored animal food compositions
|
DE3151196A1
(de)
*
|
1981-12-23 |
1983-06-30 |
Kurt Heinz Prof. Dr. 7800 Freiburg Bauer |
Verfahren zur herstellung von gut loeslichen 5-aminosalicylsaeure-arzneimittelzubereitungen
|
US6451341B1
(en)
|
1990-02-05 |
2002-09-17 |
Thomas J. Slaga |
Time release formulation of vitamins, minerals and other beneficial supplements
|
US5646187A
(en)
|
1992-05-20 |
1997-07-08 |
Ab Erik Vinnars |
Use of alpha-ketoglutarate
|
US6306430B1
(en)
|
1998-04-16 |
2001-10-23 |
The Iams Company |
Process for decreasing adiposity using vitamin a as a dietary supplement
|
US6905707B2
(en)
|
1998-05-28 |
2005-06-14 |
Medical Research Institute |
Controlled release arginine alpha ketoglutarate
|
CO5140079A1
(es)
|
1998-10-14 |
2002-03-22 |
Novartis Ag |
Composicion farmaceutica de liberacion sostenida y metodo para liberar un agente farmaceuticamente activo de liberacion sostenida y metodo para liberar un agente far- maceuticamente activo
|
US6649654B1
(en)
|
1999-11-23 |
2003-11-18 |
The Regents Of The University Of California |
Methods for identifying and using IKK inhibitors
|
AU2895502A
(en)
|
2000-12-20 |
2002-07-01 |
Alcon Universal Ltd |
Solution for removing cataracts via liquefracture
|
PL1622629T3
(pl)
*
|
2003-05-07 |
2013-12-31 |
Osteologix As |
Kompozycja do kontrolowanego uwalniania zawierająca sól strontu
|
CA2565840A1
(en)
|
2004-05-06 |
2005-11-17 |
Osteologix A/S |
High yield and rapid syntheses methods for producing metallo-organic salts
|
PL368572A1
(en)
*
|
2004-06-17 |
2005-12-27 |
Sgp & Sons Ab |
Pharmaceutical compound for prevention and therapy of increased level of cholesterol, ldl and triglycerides as well as application of the pharmaceutical compound as an agent acting against atherosclerosis and used in circulatory system affections
|
EP1778616A1
(en)
|
2004-08-09 |
2007-05-02 |
Cancer Research Technology Limited |
Alpha-ketoglutarates and their use as therapeutic agents
|
CA2589995C
(en)
|
2004-12-17 |
2016-01-05 |
Alan B. Cash |
Oxaloacetate, oxaloacetic acid, and oxaloacetate salts for treating cancer
|
US20060234250A1
(en)
|
2005-04-15 |
2006-10-19 |
Powers Ralph W Iii |
Methods of screening and compositions for life span modulators
|
US20070135376A1
(en)
|
2005-06-20 |
2007-06-14 |
Accera, Inc. |
Method to reduce oxidative damage and improve mitochondrial efficiency
|
WO2007053943A1
(en)
|
2005-11-08 |
2007-05-18 |
Multi Formulations Ltd. |
The use of compositions comprising ketoacids and amino acids for increasing muscle mass and muscle performance
|
US8367121B2
(en)
|
2005-11-23 |
2013-02-05 |
Florida A & M University |
Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease
|
PL379512A1
(pl)
|
2006-04-21 |
2007-10-29 |
Sgp & Sons Ab |
Nowe metody i ich zastosowanie
|
PL226695B1
(pl)
|
2006-07-03 |
2017-08-31 |
Danuta Kruszewska |
Środek do zastosowania w zapobieganiu i/lub hamowaniu kolonizacji Helicobacter pylori, zastosowanie soli kwasu alfa‑ketoglutarowego z metalami alkalicznymi i ziem alkalicznych do wytwarzania środka leczniczego oraz dodatku do żywności do zapobiegania i/lub hamowania kolonizacji Helicobacter pylori
|
WO2008115783A1
(en)
|
2007-03-19 |
2008-09-25 |
Metaproteomics, Llc |
Methods and compositions for promoting bone and joint health
|
CA2691746C
(en)
|
2007-07-02 |
2016-02-02 |
Entress Ab |
Use of alpha-ketoglutarate in the treatment of hypertension
|
EP2033623A1
(en)
|
2007-09-07 |
2009-03-11 |
Cutech S.R.L. |
Compositions comprising ornithine ketoglutarate (OKG)
|
JP5406643B2
(ja)
*
|
2008-09-22 |
2014-02-05 |
日本合成化学工業株式会社 |
α−オキソカルボン酸の金属塩の製造方法
|
CN101759553A
(zh)
|
2008-11-21 |
2010-06-30 |
扬子江药业集团北京海燕药业有限公司 |
α-酮酸钙的制备方法
|
DE102009016119A1
(de)
|
2009-04-03 |
2010-10-14 |
Evonik Degussa Gmbh |
Nahrungsergänzungsmittel enthaltend alpha-Ketosäuren zur Unterstützung der Diabetestherapie
|
ES2685947T3
(es)
|
2009-04-10 |
2018-10-15 |
Haiyan Qi |
Agentes antienvejecimiento
|
SG175993A1
(en)
|
2009-05-11 |
2011-12-29 |
Berg Biosystems Llc |
Methods for treatment of metabolic disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers
|
AU2010254356A1
(en)
|
2009-05-28 |
2011-12-22 |
Mars, Incorporated |
Pet food in the form of a coated kibble
|
EP2440212A4
(en)
|
2009-06-12 |
2013-03-20 |
Generex Pharm Inc |
COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CORONARY DISEASE
|
CN105534978A
(zh)
|
2009-06-30 |
2016-05-04 |
德安生医有限公司 |
用于治疗红斑痤疮或红脸相关皮肤病的含黄连素或其类似物的组合物
|
US9283257B2
(en)
|
2009-11-12 |
2016-03-15 |
Nox Technologies, Inc. |
Compositions comprising solanum tuberosum for lowering cytosolic NADH level to mimic calorie restriction
|
US20140065099A1
(en)
|
2011-02-15 |
2014-03-06 |
Ecole Polytechnique Federale De Lausanne (Epfl) |
Methods of Treating Mitochondrial Dysfunction
|
EP2699113A1
(en)
|
2011-04-18 |
2014-02-26 |
Nestec S.A. |
Nutritional compositions having alpha-hica and eicosapentaenoic acid
|
US9248185B2
(en)
|
2011-06-16 |
2016-02-02 |
President And Fellows Of Harvard College |
Methods of increasing satellite cell proliferation
|
CN102586347B
(zh)
*
|
2012-03-06 |
2014-04-09 |
江南大学 |
一种两阶段pH控制高产a-酮戊二酸的方法
|
WO2013152120A2
(en)
|
2012-04-03 |
2013-10-10 |
Whitehead Institute For Biomedical Research |
Compositions and methods for promoting intestinal stem cell function
|
ITBO20120226A1
(it)
|
2012-04-24 |
2013-10-25 |
Alfa Wassermann Spa |
Composizioni comprendenti ornitina alfa-chetoglutarato, processi per il loro ottenimento e il loro uso.
|
JP6029058B2
(ja)
*
|
2012-09-14 |
2016-11-24 |
国立研究開発法人農業・食品産業技術総合研究機構 |
シュウ酸カルシウムを含む氷核活性剤
|
KR102198633B1
(ko)
|
2012-09-19 |
2021-01-05 |
그레스포 에이비 |
뇌기능 향상용 조성물
|
CN102976927A
(zh)
*
|
2012-12-26 |
2013-03-20 |
天津天成制药有限公司 |
α-酮戊二酸钙的制备方法
|
CA2896646A1
(en)
|
2012-12-27 |
2014-07-03 |
Hayashibara Co., Ltd. |
Skin-exterior anti-ageing composition and production method therefor
|
US20150328176A1
(en)
|
2013-01-25 |
2015-11-19 |
Winning The Fight Inc. |
Composition for treatment of neurodegenerative disease
|
US9511057B2
(en)
|
2013-03-15 |
2016-12-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for treating denervation-induced muscle atrophy
|
MY180761A
(en)
|
2013-03-19 |
2020-12-08 |
Univ South Florida |
Compositions and methods for producing elevated and sustained ketosis
|
US20160263092A1
(en)
|
2013-12-19 |
2016-09-15 |
Twi Biotechnology, Inc. |
Therapeutic uses of berberine formulations
|
KR20160111529A
(ko)
|
2014-02-12 |
2016-09-26 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
노화 및 연령 관련 질환 및 증상의 치료를 위한 조성물 및 방법
|
US10258639B2
(en)
|
2014-05-06 |
2019-04-16 |
Research Development Foundation |
Methods for treating insulin resistance and for sensitizing patients to GLP1 agonist therapy
|
KR102596106B1
(ko)
|
2014-06-30 |
2023-10-30 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
연령-관련 증상 및 질환의 치료를 위한 케토부티레이트 화합물 및 조성물
|
CN110179792A
(zh)
|
2014-07-29 |
2019-08-30 |
深圳君圣泰生物技术有限公司 |
小檗碱盐、熊去氧胆酸盐、相关复方及其制备方法和应用
|
US20170266253A1
(en)
|
2014-07-31 |
2017-09-21 |
Indiana University Research And Technology Corporation |
Antithetical regulation of endothelial ace and ace2 by brg1-foxm1 complex underlies pathological cardiac hypertrophy
|
CN104529755B
(zh)
*
|
2014-12-29 |
2016-01-06 |
精晶药业股份有限公司 |
一种从转化液中分离α-酮戊二酸的方法
|
EP3280712A4
(en)
|
2015-04-06 |
2019-01-09 |
Shenzhen Hightide Biopharmaceutical, Ltd. |
CONJUGATED COMPOUNDS OF URSODESOXYCHOLIC ACID, BERBERIN OR L-CARNITINE, AND COMPOSITIONS AND METHODS COMPRISING THE SAME
|
US11426398B2
(en)
|
2015-06-10 |
2022-08-30 |
Elysium Health, Inc. |
Nicotinamide riboside and pterostilbene compositions and methods for treatment of skin disorders
|
WO2017008060A1
(en)
|
2015-07-08 |
2017-01-12 |
Unity Biotechnology, Inc. |
Compositions and methods for treating senescence-associated diseases and disorders
|
WO2018064468A1
(en)
|
2016-09-30 |
2018-04-05 |
The Regents Of The University Of California |
Alpha-ketobutyrate, alpha-ketoglutarate, and 2-hydroxybutyrate for stimulating hair growth
|
PL231635B1
(pl)
|
2017-01-03 |
2019-03-29 |
Politechnika Poznanska |
Sposób produkcji kwasu alfa-ketoglutarowego (AKG) z jednoskładnikowych roztworów wodnych
|
MX2017004010A
(es)
|
2017-03-27 |
2018-02-09 |
Antonio Hernandez Miramontes Jorge |
Mezcla de oxalacetato, alfacetoglutarato, ácido tartánico y sales de lactato de calcio y sodio, para tratar pacientes con insuficiencia renal crónica.
|
KR20230167450A
(ko)
|
2017-04-25 |
2023-12-08 |
버크 인스티튜트 포 리서치 온 에이징 |
수명 및 건강수명을 연장시키기 위한 제제
|
EP3672583A4
(en)
|
2017-08-21 |
2021-06-09 |
The Regents of the University of California |
COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES
|
SG11202102204PA
(en)
|
2018-09-25 |
2021-04-29 |
Ponce De Leon Health Designated Activity Company |
Process of making calcium alpha-ketoglutarate
|
WO2020086733A1
(en)
|
2018-10-24 |
2020-04-30 |
Ponce De Leon Health Designated Activity Company |
Nicotinamide riboside compositions for healthspan extension
|
US20220241229A1
(en)
|
2019-06-10 |
2022-08-04 |
Buck Institute For Research On Aging |
Methods and Compositions for Altering Senescence Associated Secretory Phenotype
|
CA3142494A1
(en)
|
2019-06-10 |
2020-12-17 |
Ponce De Leon Health Designated Activity Company |
Sustained-release compositions of alpha-ketoglutarate
|
EP4175978A4
(en)
|
2020-07-02 |
2024-06-26 |
Ponce de Leon Health Designated Activity Company |
COMPOSITIONS AND METHODS FOR TREATING CRP-MEDIATED DISEASES
|
CN115974679A
(zh)
*
|
2022-12-20 |
2023-04-18 |
绍兴市精益生物化工有限公司 |
α-酮戊二酸钙盐制备方法
|