CO2020016480A2 - Sales tópicas de amlodipino para el tratamiento de enfermedades anorrectales - Google Patents
Sales tópicas de amlodipino para el tratamiento de enfermedades anorrectalesInfo
- Publication number
- CO2020016480A2 CO2020016480A2 CONC2020/0016480A CO2020016480A CO2020016480A2 CO 2020016480 A2 CO2020016480 A2 CO 2020016480A2 CO 2020016480 A CO2020016480 A CO 2020016480A CO 2020016480 A2 CO2020016480 A2 CO 2020016480A2
- Authority
- CO
- Colombia
- Prior art keywords
- amlodipine
- topical
- salts
- treatment
- anorectal diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
RESUMEN DE LA INVENCIÓN Se proporciona una composición farmacéutica tópica en gel de una sal de amlodipino y métodos para su uso en el tratamiento de enfermedad anorrectal.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862679137P | 2018-06-01 | 2018-06-01 | |
US201962822400P | 2019-03-22 | 2019-03-22 | |
PCT/IB2019/000689 WO2019229535A2 (en) | 2018-06-01 | 2019-05-29 | Topical amlodipine salts for the treatment of anorectal diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2020016480A2 true CO2020016480A2 (es) | 2021-03-19 |
Family
ID=67928855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2020/0016480A CO2020016480A2 (es) | 2018-06-01 | 2020-12-26 | Sales tópicas de amlodipino para el tratamiento de enfermedades anorrectales |
Country Status (14)
Country | Link |
---|---|
US (3) | US11197848B2 (es) |
EP (1) | EP3801460A2 (es) |
JP (1) | JP2021526554A (es) |
KR (1) | KR20210023908A (es) |
CN (1) | CN112423736A (es) |
AU (1) | AU2019276832A1 (es) |
BR (1) | BR112020024395A2 (es) |
CA (1) | CA3102228A1 (es) |
CO (1) | CO2020016480A2 (es) |
CR (1) | CR20200630A (es) |
IL (1) | IL279121B1 (es) |
MX (1) | MX2020012949A (es) |
SG (1) | SG11202012365QA (es) |
WO (1) | WO2019229535A2 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11197848B2 (en) | 2018-06-01 | 2021-12-14 | Tavanta Therapeutics Hungary Incorporated | Topical amlodipine salts for the treatment of anorectal diseases |
US11253474B1 (en) | 2021-02-01 | 2022-02-22 | Liqmeds Worldwide Limited | Pharmaceutical solution of amlodipine |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1331137C (en) * | 1988-02-29 | 1994-08-02 | Pfizer, Inc. | Transdermal flux enhancing compositions |
WO1995006466A1 (en) | 1993-09-01 | 1995-03-09 | Koren Laboratories Pty. Limited | Treatment of anorectal disorders |
US8048875B1 (en) | 1997-02-24 | 2011-11-01 | S.L.A. Pharma Ag | Topical pharmaceutical composition comprising a cholinergic agent or a calcium channel blocker |
CN1127333C (zh) | 1997-02-24 | 2003-11-12 | S.L.A.药业股份公司 | 含有胆碱能药物或钙通道阻滞剂的局部用医药组合物 |
AU6767198A (en) * | 1998-03-26 | 1999-05-03 | Dr. Reddy's Laboratories Limited | Stable pharmaceutical composition containing amlodipine besylate and atenol ol |
AU764921B2 (en) * | 1998-12-14 | 2003-09-04 | Cellegy Pharmaceuticals, Inc. | Compositions and methods for the treatment of anorectal disorders |
US6391869B1 (en) | 1998-12-14 | 2002-05-21 | Cellergy Pharmaceuticals, Inc. | Compositions and methods for the treatment of anorectal disorders |
IL129102A0 (en) * | 1999-03-22 | 2000-02-17 | J P M E D Ltd | An emulsion |
IL137275A0 (en) | 2000-07-12 | 2001-07-24 | Yosefus Azaria | Pharmaceutical composition for the treatment of anal fissures |
US8425892B2 (en) | 2001-10-29 | 2013-04-23 | Columbia Laboratories, Inc. | Extended, controlled-release pharmaceutical compositions using charged polymers |
WO2003075851A2 (en) | 2002-03-06 | 2003-09-18 | Cellegy Pharmaceuticals, Inc. | Compositions and methods for the treatment of anorectal disorders |
CA2609953A1 (en) * | 2005-05-09 | 2007-04-12 | Foamix Ltd. | Saccharide foamable compositions |
WO2008022032A2 (en) | 2006-08-11 | 2008-02-21 | Solvay Pharmaceuticals, Inc. | Topical pharmaceutical compositions comprising calcium-channel blocker and method of using same |
KR20090074158A (ko) * | 2006-09-01 | 2009-07-06 | 모베르그 데르마 아베 | 디하이드로피리딘 칼슘 길항제를 포함하는 국소성 조성물 |
WO2008154368A2 (en) * | 2007-06-08 | 2008-12-18 | University Of Virginia Patent Foundation | Topical poloxamer formulations for enhancing microvascular flow: compositions and uses thereof |
JP5072748B2 (ja) * | 2007-07-10 | 2012-11-14 | 株式会社 メドレックス | アムロジピンの安定な液剤とゼリー剤 |
CN101468001A (zh) * | 2007-12-29 | 2009-07-01 | 北京瑞康医药技术有限公司 | 含有氨氯地平系列盐和他汀类药物的治疗组合物 |
US8686040B2 (en) | 2008-03-31 | 2014-04-01 | Rdd Pharma Ltd. | Method for treating anal pruritis and other perianal disorders |
JP2009256216A (ja) * | 2008-04-14 | 2009-11-05 | Towa Yakuhin Kk | 溶液状態で安定なアムロジピンベシル酸塩内服用液剤 |
RU2011111206A (ru) * | 2008-10-31 | 2012-12-10 | Моберг Дерма Аб | Композиции для местного применения, содержащие комбинацию по меньшей мере двух агентов, усиливающих проникновение |
GB0906868D0 (en) * | 2009-04-21 | 2009-06-03 | Rabin Bennie | Amlodipine salt compositions |
JP5960061B2 (ja) | 2009-12-18 | 2016-08-02 | エクソドス ライフ サイエンシーズ リミテッド パートナーシップ | 末梢血管疾患を治療するための方法および組成物 |
US10471131B2 (en) * | 2012-01-19 | 2019-11-12 | Hybrid Medical, Llc | Topical therapeutic formulations |
BR112014028610A2 (pt) | 2012-05-17 | 2017-06-27 | Contract Pharmaceuticals Ltd | formulações de vesícula não iônica de bloqueadores de canal de cálcio |
RU2592366C2 (ru) | 2013-07-22 | 2016-07-20 | Общество с ограниченной ответственностью "ХИЛИНГ ФАРМ" | Фармакологическая композиция для лечения проктологических заболеваний (варианты) |
WO2015051336A1 (en) | 2013-10-03 | 2015-04-09 | David Wise | Compositions and methods for treating pelvic pain and other conditions |
WO2016118040A1 (ru) | 2015-01-21 | 2016-07-28 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" | Гель, содержащий нифедипин и лидокаина гидрохлорид, его применение и способ приготовления с использованием нанотехнологий |
IT201800002413A1 (it) | 2018-02-05 | 2019-08-05 | Carmine Antropoli | "composizione a base di nifedipina per uso nel trattamento delle ragadi anali e proctalgie" |
BR102018008324A2 (pt) | 2018-04-25 | 2019-11-05 | Laboratorios Ferring Ltda | composição farmacêutica de uso tópico e processo de fabricação de composição farmacêutica de uso tópico |
WO2019226542A1 (en) | 2018-05-22 | 2019-11-28 | Weinberg Assa | Methods for prevention and treatment of pressure ulcers caused by ischemia using contact vasodilators |
US11197848B2 (en) | 2018-06-01 | 2021-12-14 | Tavanta Therapeutics Hungary Incorporated | Topical amlodipine salts for the treatment of anorectal diseases |
-
2019
- 2019-05-29 US US16/425,028 patent/US11197848B2/en active Active
- 2019-05-29 SG SG11202012365QA patent/SG11202012365QA/en unknown
- 2019-05-29 BR BR112020024395-7A patent/BR112020024395A2/pt unknown
- 2019-05-29 KR KR1020207037931A patent/KR20210023908A/ko unknown
- 2019-05-29 JP JP2021517118A patent/JP2021526554A/ja active Pending
- 2019-05-29 IL IL279121A patent/IL279121B1/en unknown
- 2019-05-29 MX MX2020012949A patent/MX2020012949A/es unknown
- 2019-05-29 AU AU2019276832A patent/AU2019276832A1/en active Pending
- 2019-05-29 WO PCT/IB2019/000689 patent/WO2019229535A2/en unknown
- 2019-05-29 EP EP19766349.5A patent/EP3801460A2/en active Pending
- 2019-05-29 CN CN201980047697.9A patent/CN112423736A/zh active Pending
- 2019-05-29 CR CR20200630A patent/CR20200630A/es unknown
- 2019-05-29 CA CA3102228A patent/CA3102228A1/en active Pending
-
2020
- 2020-12-26 CO CONC2020/0016480A patent/CO2020016480A2/es unknown
-
2021
- 2021-07-16 US US17/305,916 patent/US11766428B2/en active Active
-
2023
- 2023-09-08 US US18/244,155 patent/US20230414591A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA3102228A1 (en) | 2019-12-05 |
US11766428B2 (en) | 2023-09-26 |
CR20200630A (es) | 2021-05-26 |
JP2021526554A (ja) | 2021-10-07 |
WO2019229535A3 (en) | 2020-01-30 |
US20230414591A1 (en) | 2023-12-28 |
US11197848B2 (en) | 2021-12-14 |
SG11202012365QA (en) | 2021-01-28 |
CN112423736A (zh) | 2021-02-26 |
US20220000850A1 (en) | 2022-01-06 |
KR20210023908A (ko) | 2021-03-04 |
WO2019229535A2 (en) | 2019-12-05 |
IL279121B1 (en) | 2024-02-01 |
EP3801460A2 (en) | 2021-04-14 |
IL279121A (en) | 2021-01-31 |
AU2019276832A1 (en) | 2021-01-21 |
BR112020024395A2 (pt) | 2021-03-02 |
MX2020012949A (es) | 2021-05-12 |
US20190365732A1 (en) | 2019-12-05 |
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