CO2017008437A2 - Métodos de purificación de cannabinoides, composiciones y kits de los mismos - Google Patents
Métodos de purificación de cannabinoides, composiciones y kits de los mismosInfo
- Publication number
- CO2017008437A2 CO2017008437A2 CONC2017/0008437A CO2017008437A CO2017008437A2 CO 2017008437 A2 CO2017008437 A2 CO 2017008437A2 CO 2017008437 A CO2017008437 A CO 2017008437A CO 2017008437 A2 CO2017008437 A2 CO 2017008437A2
- Authority
- CO
- Colombia
- Prior art keywords
- compositions
- kits
- purification methods
- cannabinoids
- cannabinoid
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0288—Applications, solvents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0004—Crystallisation cooling by heat exchange
- B01D9/0013—Crystallisation cooling by heat exchange by indirect heat exchange
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/68—Purification; separation; Use of additives, e.g. for stabilisation
- C07C37/685—Processes comprising at least two steps in series
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/68—Purification; separation; Use of additives, e.g. for stabilisation
- C07C37/70—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment
- C07C37/84—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment by crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/18—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring
- C07C39/19—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring containing carbon-to-carbon double bonds but no carbon-to-carbon triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
- C07C65/19—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups having unsaturation outside the aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Analytical Chemistry (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Thermal Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Physics & Mathematics (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
Abstract
RESUMEN La presente memoria descriptiva describe métodos para la purificación de uno o más cannabinoides a partir de material vegetal, los cannabinoides purificados y composiciones farmacéuticas que comprenden uno o más cannabinoides producidos por el método, y utiliza métodos descritos para tratar una enfermedad o dolencia, empleando tales cannabinoides purificados y composiciones farmacéuticas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562106644P | 2015-01-22 | 2015-01-22 | |
PCT/EP2016/051388 WO2016116628A1 (en) | 2015-01-22 | 2016-01-22 | Methods of purifying cannabinoids, compositions and kits thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2017008437A2 true CO2017008437A2 (es) | 2018-01-05 |
Family
ID=55349794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2017/0008437A CO2017008437A2 (es) | 2015-01-22 | 2017-08-18 | Métodos de purificación de cannabinoides, composiciones y kits de los mismos |
Country Status (21)
Country | Link |
---|---|
US (1) | US9765000B2 (es) |
EP (2) | EP3247371B1 (es) |
JP (1) | JP6342587B2 (es) |
CN (2) | CN110563574A (es) |
AU (2) | AU2016210070B2 (es) |
BR (2) | BR112017015536B1 (es) |
CA (1) | CA2977421C (es) |
CL (1) | CL2017001873A1 (es) |
CO (1) | CO2017008437A2 (es) |
CY (1) | CY1122994T1 (es) |
DK (1) | DK3247371T3 (es) |
ES (1) | ES2801005T3 (es) |
HK (1) | HK1246663A1 (es) |
IL (1) | IL253576B (es) |
MX (1) | MX364559B (es) |
NZ (1) | NZ734714A (es) |
PE (2) | PE20171108A1 (es) |
PT (1) | PT3247371T (es) |
SI (1) | SI3247371T1 (es) |
UY (2) | UY36530A (es) |
WO (1) | WO2016116628A1 (es) |
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US11034639B2 (en) | 2015-01-22 | 2021-06-15 | Phytoplant Research S.L. | Methods of purifying cannabinoids using liquid:liquid chromatography |
BG112018A (bg) * | 2015-05-22 | 2016-11-30 | "Побелч-Гле" Оод | Метод за получаване на канабиноиден извлек от коноп |
US10239808B1 (en) | 2016-12-07 | 2019-03-26 | Canopy Holdings, LLC | Cannabis extracts |
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US10772837B2 (en) * | 2017-03-16 | 2020-09-15 | CannTab Therapeutics, Ltd | Modified release multi-layer tablet cannabinoid formulations |
US10238600B2 (en) * | 2017-04-13 | 2019-03-26 | Richard C. Fuisz | Package, system and methods for custody and control of drugs, and method and composition for making an oral soluble film, containing at least one active agent |
WO2018233781A1 (en) | 2017-06-23 | 2018-12-27 | Medcan Pharma A/S | SACHET OF CANNABINOIDS |
IT201700085508A1 (it) * | 2017-07-26 | 2019-01-26 | Inalco S R L | Metodo per la produzione di cannabinoidi da varietà di canapa industriale |
US10814338B2 (en) | 2017-08-09 | 2020-10-27 | Delta Separations, Llc | Device, system and methods for separation and purification of organic compounds from botanical material |
US10308626B1 (en) | 2018-07-02 | 2019-06-04 | Pratt Bethers | Crystal purification in a glass or metal container |
US10851076B2 (en) | 2017-08-10 | 2020-12-01 | Pratt Bethers | Method for purifying crystals using solvent vapors |
US10960322B2 (en) * | 2018-07-02 | 2021-03-30 | Pratt Bethers | Apparatus for purifying crystals using solvent vapors |
EP3449992A1 (en) * | 2017-09-04 | 2019-03-06 | Bionorica Ethics GmbH | Recovery of acidic cannabinoids from plant material |
WO2019071302A1 (en) * | 2017-10-09 | 2019-04-18 | The University Of Sydney | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING EPILEPSY CRISES |
BR112020007891B1 (pt) * | 2017-10-30 | 2024-02-15 | Whistler Technologies Corp | Método para produzir produtos de extração ativos a partir de resina de cannabis |
US10941102B2 (en) * | 2017-11-29 | 2021-03-09 | Robert Henry Wohleb | Aqueous leaching method to produce microcrystalline powder |
US20190192429A1 (en) * | 2017-12-27 | 2019-06-27 | CannScience Innovations Inc. | Sublingual formulations comprising cannabis resin, methods for making same and uses thereof |
US11179340B2 (en) * | 2017-12-29 | 2021-11-23 | TGC Network LLC | Cannabidiol dosage form |
CA3089490A1 (en) | 2018-01-29 | 2019-08-01 | Phytoplant Research S.L | Methods of purifying cannabinoids using liquid:liquid chromatography |
CA3089994A1 (en) | 2018-01-31 | 2019-08-08 | Canopy Holdings, LLC | Hemp powder |
US10463986B2 (en) | 2018-02-07 | 2019-11-05 | Metagreen Ventures | Extraction of organic products from plant and animal materials |
KR102374793B1 (ko) | 2018-02-20 | 2022-03-17 | 엠와이엠디 파마슈티컬스 (플로리다), 인코포레이티드 | 물질 중독 및 다른 장애 치료용 유전자 변형 칸나비스 사티바 식물 및 변형된 칸나비노이드 화합물 |
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WO2019211772A1 (en) * | 2018-05-03 | 2019-11-07 | Radient Technologies Inc. | Obtaining extracts in a solid form |
SE542659C2 (en) * | 2018-07-10 | 2020-06-23 | Stora Enso Oyj | Method for desulfurization of methanol |
EP3833369A4 (en) * | 2018-08-08 | 2022-05-04 | Neptune Wellness Solutions Inc. | PROCESS FOR COLD EXTRACTION OF CANNABINOIDS AND TERPENES FROM CANNABIS BY ORGANIC SOLVENTS |
WO2020077153A1 (en) | 2018-10-10 | 2020-04-16 | Canopy Holdings, LLC | Synthesis of cannabigerol |
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CA3122481A1 (en) * | 2018-12-11 | 2020-06-18 | Naturalia Ingredients S.R.L. | Extraction method and composition obtained therefrom |
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GB0222077D0 (en) * | 2002-09-23 | 2002-10-30 | Gw Pharma Ltd | Methods of preparing cannabinoids from plant material |
US7923558B2 (en) * | 2004-07-19 | 2011-04-12 | Cilag Ltd. | Method for obtaining pure tetrahydrocannabinol |
ATE493977T1 (de) * | 2007-10-02 | 2011-01-15 | Vivacell Biotechnology Espana S L | Zusammensetzung mit nicht-psychotropen cannabinoiden zur behandlung von entzündungserkrankungen |
DK2760444T3 (da) * | 2011-09-29 | 2020-07-27 | Thc Pharm Gmbh The Health Concept | Cannabinoidcarboxylsyrer, salte af cannabinoidcarboxylsyrer, fremstilling og anvendelse deraf |
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