CN221302935U

CN221302935U - Heating concentration device for analyzer

Info

Publication number: CN221302935U
Application number: CN202322879521.6U
Authority: CN
Inventors: 冯孟辉; 宋家玉; 秦超; 刘凯; 李向广; 蔡克亚
Original assignee: Autobio Labtec Instruments Zhengzhou Co Ltd
Current assignee: Autobio Labtec Instruments Zhengzhou Co Ltd
Priority date: 2023-10-26
Filing date: 2023-10-26
Publication date: 2024-07-09
Anticipated expiration: 2033-10-26

Abstract

The utility model discloses a heating and concentrating device for an analyzer, which comprises a frame body, a heating structure and a steam condensing unit, wherein the heating structure is provided with a heating seat arranged on the frame body, an electric heating rod and a top cover which are inserted into the heating seat, and the top cover and the heating seat are sealed to form a sealed cavity; the steam condensing unit comprises a double-chamber condensing pipe, a working pump and a condensing medium pipeline, the condensing pipe is provided with a condensing channel and a steam channel, the inlet of the steam channel is communicated with the sealed chamber through a connecting pipeline, and the outlet of the steam channel is connected with the waste liquid bottle; the working pump is communicated with the connecting pipeline, and the condensing channel is communicated with the condensing medium pipeline. The utility model integrates and installs the heating structure on the frame body, has compact structure and small volume, can be integrally installed in the analyzer, realizes the follow-up detection of samples, and reduces the pretreatment workload of detection personnel; the utility model has high heating efficiency and improves the concentration efficiency of the sample; the organic steam is condensed and recovered by a condensing medium to prevent the steam from escaping.

Description

Heating concentration device for analyzer

Technical Field

The present utility model relates to a sample processing module of an analyzer, and more particularly, to a heating and concentrating device for an analyzer.

Background

In the field of in-vitro diagnosis, an automatic analysis instrument gradually becomes a mainstream instrument for analysis and detection due to the advantages of simplicity in operation, high efficiency, less man-machine interaction and the like. The detection sensitivity is poor and the detection result is irregular due to the influence of various factors, so that the sample is usually concentrated and purified in the actual detection, and the sample pretreatment of the analyzers such as mass spectrometry, biochemistry, immunity, molecular diagnosis and the like involves the concentration and purification of the sample. At present, common concentration mode in laboratory mainly includes nitrogen blowing, evacuation concentration etc. wherein nitrogen blows the volume of appearance huge, and the surface air current alignment sample appears liquid easily and splashes, exists the target and loses the condition, and the volume of evacuation concentration equipment is great, hardly integrates in the automated analysis instrument, and sample concentration inefficiency can't satisfy the demand of examining along with going of sample.

Disclosure of Invention

In view of the above, the present utility model provides a heating and concentrating device for an analyzer, which has a compact structure and a small volume, and can be integrally installed in the analyzer to meet the requirement of sample follow-up detection.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

The heating and concentrating device for the analyzer comprises a frame body; and also comprises

The heating structure is provided with a heating seat arranged on the frame body, an electric heating rod inserted in the heating seat and a top cover arranged on the heating seat in a sealing way, the heating seat is provided with a positioning groove for placing the reaction container, the top cover and the heating seat are sealed to form a sealing cavity, and the upper opening of the reaction container is positioned in the sealing cavity;

the steam condensing unit comprises a double-chamber condensing pipe, a working pump and a condensing medium pipeline, the condensing pipe is provided with a condensing channel and a steam channel, the inlet of the steam channel is communicated with the sealed chamber through a connecting pipeline, and the outlet of the steam channel is connected with a waste liquid bottle; the working pump is communicated with the connecting pipeline, and the condensing channel is communicated with the condensing medium pipeline.

The beneficial effects are that: the utility model integrates and installs the heating structure on the frame body, has compact structure and small volume, can be integrally installed in the analyzer, further realizes the follow-up detection of samples and reduces the pretreatment workload of detection personnel. The heating seat provided by the utility model is heated by the plurality of heating rods, so that the heating efficiency is high, the concentration efficiency of a sample is further improved, and the requirement of clinical detection flux is met. During actual processing, the heating seat is coated with the heat insulation layer, so that heat loss is reduced, and scalding can be prevented.

When in actual connection, the flow direction of the condensing medium in the condensing channel is opposite to the flow direction of the steam in the steam channel, so that the effect of condensing the steam is achieved. When the device works, the working pump is used for extracting the organic steam and condensing the organic steam by using a condensing medium, so that continuous condensation is realized, and the concentration efficiency is further ensured. In addition, the working pump enables the sealing cavity to be in a negative pressure state, so that the boiling point of liquid can be reduced to a certain extent, and the concentration efficiency is improved.

Preferably, the top cover is provided with a steam groove vertically corresponding to the positioning groove, the top cover is provided with an exhaust hole communicated with the steam groove, and the exhaust hole is communicated with the steam channel. When the top cover is closed, the steam groove and the positioning groove are in sealing connection to form a sealing cavity, so that air suction and air exchange are facilitated.

Preferably, the top cover is also provided with an air inlet communicated with the steam tank, and the air inlet is connected with an external inert gas source. According to the utility model, the air inlet is arranged on the top cover, so that an inert gas source can be fed into the sealed cavity through the air inlet, and air pollution to a sample is prevented during gas exchange; inert gas enters the sealed cavity through the air inlet hole, and the working pump pumps out the gas through the air outlet hole, so that the flow speed of cavity steam is accelerated, and the evaporation efficiency is improved.

Preferably, a sealing ring is arranged between the top cover and the top plate of the heating seat. In actual installation, an annular groove can be arranged on the top plate of the heating seat, and the sealing ring is embedded in the annular groove so as to ensure the sealing performance of the sealing chamber; of course, the annular groove can also be arranged on the top cover,

Preferably, the steam condensing unit further comprises a pair of supports arranged at intervals, and the condensing tube is fixed on the supports. In actual installation, the condenser tube may be mounted at a suitable location of the analyzer via a mount.

Preferably, the heating structure further comprises a temperature sensor inserted in the heating seat. When in actual installation, the signal input end of the temperature sensor is connected with the control system of the analyzer so as to transmit the detected temperature to the control system, and the control system controls the heating condition of the heating rod to keep the heating seat constant in temperature.

Preferably, the heating and concentrating device further comprises a cover opening and closing mechanism for driving the top cover to open and close; the side edge of the top cover is provided with a rotating shaft, the rotating shaft is rotatably arranged at one side edge of the heating seat, and the cover opening and closing mechanism is in transmission connection with the rotating shaft. The cover opening and closing mechanism can control the automatic opening and closing of the top cover by controlling the direction of the rotating shaft, thereby meeting the automatic detection requirement of the analyzer.

More preferably, the cover opening and closing mechanism comprises a motor arranged in the frame body and a connecting rod assembly driven by the motor; the connecting rod assembly is provided with a first connecting rod and a second connecting rod which are hinged, the end part of the second connecting rod is fixedly connected with the rotating shaft, and one end part of the first connecting rod is fixedly connected with the power shaft of the motor. The utility model adopts the motor and the connecting rod assembly to realize the opening and closing of the top cover, has compact structure, small occupied space and high degree of automation.

Preferably, the frame body comprises a fixed plate and a plurality of vertical rods vertically arranged on the fixed plate, and the bottom plate of the heating seat is fixed at the tops of the vertical rods; the motor is arranged in the frame body, so that the utility model is minimized in volume to the greatest extent, and the integrated installation of a plurality of heating concentration devices in the analyzer is realized.

Preferably, a riser is arranged on the fixing plate, the motor is fixedly connected with the riser through a pair of mounting plates, and the machine body of the motor is arranged at intervals with the riser.

Compared with the prior art, the utility model has the advantages that:

The utility model has the advantages that the whole structure is vertically arranged, namely, the heating seat is arranged in the frame body, the motor is arranged in the frame body, the structure is compact, the volume is small, the high-efficiency concentration can be realized, the integrated installation in the analyzer can be realized, and the technical defect that the existing analyzer can not realize the follow-up detection of samples is overcome.

According to the utility model, the heating rod is used as a heating source and is matched with the steam condensing unit, so that the negative pressure air suction of the sealed cavity can be realized, the boiling point of liquid is reduced, and the concentration efficiency is improved; the steam condensing unit can realize condensation recovery of organic steam, and the top cover and the heating seat are designed in a sealing way, so that the organic steam is effectively prevented from escaping.

Drawings

Fig. 1 is a schematic view of the structure of the present utility model (with the top cover in a closed state).

Fig. 2 is a schematic view of another state of the present utility model (the top cover is in an opened state).

FIG. 3 is a cross-sectional view of the heating structure of the present utility model (with the top cover omitted).

Fig. 4 is a bottom view of fig. 3.

Fig. 5 is a schematic view of a condenser tube according to the present utility model.

Fig. 6 is a schematic view of a vapor condensing unit according to the present utility model.

Fig. 7 is a side view of the condenser tube of fig. 6.

Fig. 8 is a schematic block circuit diagram of the present utility model.

Detailed Description

The following describes embodiments of the present invention in detail with reference to the accompanying drawings, and the embodiments and specific operation procedures are given by the embodiments of the present invention under the premise of the technical solution of the present invention, but the scope of protection of the present invention is not limited to the following embodiments.

It should be noted that in the description of the present invention, relational terms such as "first" and "second", and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions.

In the description of the present invention, the terms "coupled," "connected," and "connected," as may be used broadly, and may be connected, for example, fixedly, detachably, or integrally, unless otherwise specifically defined and limited; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those skilled in the art in specific cases.

The utility model provides a heating concentration device for an analyzer, which is small in size and occupied space, can realize high-efficiency concentration and purification of a sample, and can avoid sample loss.

Referring to fig. 1-4, the heating and concentrating device for an analyzer according to the present utility model includes a frame 1, a heating structure 2, a steam condensing unit, and a cover opening and closing mechanism, wherein the heating structure 2 is disposed on the upper portion of the frame 1, a condensing tube 3.1 of the steam condensing unit can be mounted at a suitable position of a mass spectrometer, and the cover opening and closing mechanism is mounted on the frame 1, so that the device has a compact structure, a small volume, can achieve automatic concentration, has high concentration efficiency, and can be batch-mounted in the analyzer.

Specifically, as can be seen from fig. 1-3, the heating structure 2 comprises a heating seat 2.1 arranged on the frame body 1, an electric heating rod 2.2 inserted in the heating seat 2.1 (the electric heating rod 2.2 is inserted into the heating seat 2.1 from bottom to top), and a top cover 2.3 arranged on the heating seat 2.1 in a sealing manner, the heating seat 2.1 is provided with a positioning groove 2.5 for placing a reaction cup 2.4, the top cover 2.3 is provided with a steam groove 2.10 (for providing a certain space for organic steam and facilitating the air flow exchange of inert gas), the top cover 2.3 and a top plate 2.6 of the heating seat 2.1 are in sealing connection so as to form a sealing chamber, and a cup mouth of the reaction cup 2.4 is positioned in the sealing chamber.

In actual installation, the number of the electric heating rods 2.2 is four, and of course, one, two or three electric heating rods 2.2 can be independently controlled, and the electrifying heating condition of the electric heating rods 2.2 can be controlled according to the temperature required by concentration.

In actual installation, as can be seen from fig. 3, the outer side of the heating seat 2.1 is provided with a side plate 2.7, a top plate 2.6 and a bottom plate 2.8, and a heat insulation layer is arranged between the heating seat 2.1 and the side plate 2.7, between the heating seat 2.1 and the top plate 2.6 and between the heating seat 2.1 and the bottom plate 2.8, so that heat damage is reduced; the side plates 2.7, the top plate 2.6 and the bottom plate 2.8 are made of heat insulation materials, so that the heat insulation performance is further improved, and scalding can be avoided.

As can be seen in connection with fig. 4, the heating structure 2 further comprises a temperature sensor 2.9 inserted in the heating seat 2.1 from bottom to top, and a probe of the temperature sensor 2.9 is close to the reaction cup 2.4. When in actual installation, the signal input end of the temperature sensor 2.9 is connected with the control system of the analyzer so as to transmit the detected temperature to the control system, and the heating condition of the heating rod is controlled by the control system, so that the heating temperature of the heating seat 2.1 is kept at the specified temperature.

As can be seen from fig. 2, the top cover 2.3 is provided with a vent hole 2.11 (the vent hole 2.11 is provided with a vent joint), which is communicated with the steam channel 3.1b through a connecting pipeline, and the vent joint at the vent hole 2.11 is communicated with the steam channel 2.10; the top cover 2.3 is also provided with an air inlet hole 2.12 communicated with the steam tank 2.10, the air inlet hole 2.12 is connected with an external inert gas source (preferably nitrogen, argon and the like), and the inert gas source can be sent into the sealed cavity through the air inlet hole 2.12 to prevent air from polluting a sample during air exchange; inert gas enters the sealed cavity through the air inlet hole 2.12, and organic steam which is heated and evaporated can be pumped out through the working pump 3.2 which is described later, so that the flow speed of the cavity steam is accelerated, and the evaporation efficiency is improved.

As can be seen from fig. 4-7, the steam condensing unit comprises a double-chamber condensing tube 3.1, a working pump 3.2 and a condensing medium pipeline, wherein the condensing tube 3.1 is provided with a condensing channel 3.1a and a steam channel 3.1b, two ends of the condensing tube 3.1 are provided with a first inlet joint 3.1c and a first outlet joint 3.1d which are communicated with the condensing channel 3.1a, a second inlet joint 3.1e and a second outlet joint 3.1f which are communicated with the steam channel 3.1b, and the flow direction of the condensing medium in the condensing channel 3.1a is opposite to the flow direction of the steam in the steam channel 3.1b, so that the effect of condensing the steam is achieved.

The inlet of the steam channel 3.1b is communicated with the sealed cavity through a connecting pipeline, a working pump 3.2 (such as a diaphragm pump) is communicated and arranged on the connecting pipeline, organic steam is pumped into the steam channel 3.1b by the working pump 3.2, condensation is carried out by a condensing medium, and a second outlet joint 3.1f of the steam channel 3.1b is connected with a waste liquid bottle 3.4 of the analyzer so as to recycle the condensed organic solvent;

The condensation channel 3.1a of the condensation pipe 3.1 is connected in series with a condensation medium pipeline (with a liquid pump for providing power for the condensation medium), and the condensation medium with low temperature is used for condensing the organic steam, and the condensation medium is preferably condensed water with the temperature below 25 ℃. During operation, the electric heating rod 2.2 heats the reaction cup 2.4 through the heating seat 2.1 body, and the generated organic steam is pumped into the steam channel 3.1b by the working pump 3.2 to exchange heat with the condensing medium, so that continuous condensation is realized, and the concentration efficiency is ensured. In addition, the working pump 3.2 enables the sealing chamber to be in a negative pressure state, so that the boiling point of liquid can be reduced to a certain extent, and the concentration efficiency can be improved.

In one embodiment of the utility model, a sealing ring is arranged between the top cover 2.3 and the heating seat 2.1 in order to ensure sealing performance between the top cover 2.3 and the top plate 2.6. As can be seen from fig. 2 and 3, the top plate 2.6 is provided with an annular groove 2.13, the sealing ring is embedded in the annular groove 2.13, and when the top cover 2.3 is closed, the lower surface of the top cover 2.3 is pressed on the sealing ring, so that the sealing performance of a sealing cavity between the top cover 2.3 and the top plate 2.6 is effectively ensured, and steam is prevented from escaping. Of course, in actual installation, an annular groove can be formed in the lower surface of the top cover 2.3, and the sealing ring is embedded in the annular groove, so that the upper surface of the top plate 2.6 is tightly attached to the lower surface of the top cover 2.3, and the sealing performance of the middle sealing cavity is ensured.

In one embodiment of the utility model, the steam condensing unit further comprises a pair of supports 3.3 arranged at intervals, the condensing tube 3.1 is fixed on the supports 3.3, and the condensing tube 3.1 can be installed at a proper position of the analyzer through the supports 3.3, so that the installation is convenient, and the embodiment is shown in fig. 3-4.

Referring to fig. 1, a rotating shaft is disposed at a side edge of the top cover 2.3, and is rotatably disposed in a mounting sleeve F at a side edge of the top plate 2.6, and the cover opening and closing mechanism is in transmission connection with the rotating shaft, and realizes opening and closing of the top cover 2.3 by changing a direction of the rotating shaft, so as to meet an automatic detection requirement of an analyzer.

As can be seen from fig. 1-2, the cover opening and closing mechanism comprises a motor 4.1 arranged in the frame body 1 and a connecting rod assembly driven by the motor 4.1, wherein the connecting rod assembly is positioned on one side of the heating seat 2.1, the connecting rod assembly is provided with a first connecting rod 4.2 and a second connecting rod 4.3 which are hinged, the end part of the second connecting rod 4.3 is fixedly connected with the end part of the rotating shaft, one end part of the first connecting rod 4.2 is fixedly connected with a power shaft of the motor 4.1, and the cover opening and closing mechanism is simple and compact in structure, small in occupied space and convenient to install.

In a preferred embodiment of the present utility model, as can be seen in connection with fig. 1-2, the frame 1 comprises a fixed plate 1.1 and a plurality of uprights 1.2 vertically arranged on the fixed plate 1.1, the bottom plate 2.8 of the heating seat 2.1 being fixed on top of the plurality of uprights 1.2; the fixing plate 1.1 is provided with a vertical plate 1.3, the motor 4.1 is fixedly connected with the vertical plate 1.3 through a pair of mounting plates 1.4, and the motor 4.1 is positioned below the heating seat 2.1; the machine body of the motor 4.1 and the vertical plate 1.3 are arranged at intervals to enable cables of the electric heating rod 2.2 and the temperature sensor 2.9 to pass through, so that the structure is compact, the volume of the utility model is minimized to the greatest extent, and the integrated installation of a plurality of heating concentration devices in the analyzer is realized.

In order to realize the automatic control of the utility model, the signal output end of the temperature sensor 2.9 is connected with the signal input end of the control system of the analyzer, and the control output end of the control system is respectively connected with the control input end of the motor 4.1 and the control input end of the electric heating rod 2.2 so as to realize the automatic control of the motor 4.1 and the electric heating rod 2.2, and the control output end of the control system is specifically shown in fig. 8. It should be noted that, the control system of the analyzer is an instrument self-contained system, which may be an industrial personal computer with computer properties, or may be a general purpose processor, a special purpose processor, a conventional processor, a Digital Signal Processor (DSP), a plurality of microprocessors, one or more microprocessors associated with a DSP core, a controller, a microcontroller, an Application Specific Integrated Circuit (ASIC), a Field Programmable Gate Array (FPGA) circuit, any other type of Integrated Circuit (IC), a state machine, or the like.

The working principle and working process of the utility model are as follows: starting the motor 4.1, driving the top cover 2.3 to open by the motor 4.1 through the connecting rod assembly, and placing the reaction cup 2.4 into the positioning groove 2.5; the motor 4.1 works in the opposite direction to enable the top cover 2.3 to be sealed and arranged on the top plate 2.6 of the heating seat 2.1, and the top cover 2.3 is connected with the top plate 2.6 in a sealing way to enable the reaction cup 2.4 to be positioned in the sealing cavity; the electric heating rod 2.2 heats the reaction cup 2.4 through the heating seat 2.1 to boil the liquid in the reaction cup 2.4, the condensation circulation unit and an external inert gas source are started in the process, the inert gas enters the sealed cavity, the working pump 3.2 pumps the organic steam into the steam channel 3.1b of the condensation pipe 3.1, the organic steam is condensed by utilizing the condensed water and is recycled into the waste liquid bottle 3.4, and the recycling of the organic steam is realized, so that the pollution is reduced.

In the concentration process, inert gas is introduced into the sealed cavity, so that the gas flow rate on the surface of the liquid of the reaction cup 2.4 can be increased, the effect of accelerating the gas flow is achieved, and the evaporation efficiency is further improved.

The heating structure 2 and the motor 4.1 are arranged on the frame body 1, and the utility model has compact structure, small volume, small occupied space and high concentration efficiency. When the device is installed, one or more than two devices can be integrated in the analyzer according to the needs of the analyzer, so that the sample flux needs of the analyzer are met, the detection efficiency is improved, the follow-up detection of samples is realized, and the concentration equipment investment of a user can be reduced.

It should be emphasized that the above description is merely a preferred embodiment of the present invention, and the present invention is not limited to the above embodiment, but may be modified without inventive effort or equivalent substitution of some of the technical features described in the above embodiments by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A heating and concentrating device for an analyzer, characterized by: comprises a frame body; and also comprises

2. The heating and concentrating apparatus for an analyzer of claim 1 wherein: the steam tank that corresponds from top to bottom with the constant head tank has been seted up on the top cap, set up on the top cap with the exhaust hole of steam tank intercommunication, exhaust hole department with steam channel intercommunication.

3. The heating and concentrating apparatus for an analyzer of claim 2 wherein: the top cover is also provided with an air inlet communicated with the steam tank, and the air inlet is connected with an external inert gas source.

4. The heating and concentrating apparatus for an analyzer of claim 2 wherein: and a sealing ring is arranged between the top cover and the top plate of the heating seat.

5. The heating and concentrating apparatus for an analyzer of claim 1 wherein: the steam condensing unit further comprises a pair of supports arranged at intervals, and the condensing pipe is fixed on the supports.

6. The heating and concentrating apparatus for an analyzer of claim 1 wherein: the heating structure further comprises a temperature sensor inserted in the heating seat.

7. The heating and concentrating apparatus for an analyzer of claim 1 wherein: the device also comprises a cover opening and closing mechanism for driving the top cover to open and close; the side edge of the top cover is provided with a rotating shaft, the rotating shaft is rotatably arranged at one side edge of the heating seat, and the cover opening and closing mechanism is in transmission connection with the rotating shaft.

8. The heating and concentrating apparatus for an analyzer of claim 7 wherein: the cover opening and closing mechanism comprises a motor arranged in the frame body and a connecting rod assembly driven by the motor;

the connecting rod assembly is provided with a first connecting rod and a second connecting rod which are hinged, the end part of the second connecting rod is fixedly connected with the rotating shaft, and one end part of the first connecting rod is fixedly connected with the power shaft of the motor.

9. The heating and concentrating apparatus for an analyzer of claim 8 wherein: the frame body comprises a fixed plate and a plurality of vertical rods vertically arranged on the fixed plate, and the bottom plate of the heating seat is fixed at the tops of the vertical rods; the motor is arranged in the frame body.

10. The heating and concentrating apparatus for an analyzer of claim 9 wherein: the motor is fixedly connected with the vertical plates through a pair of mounting plates, and the machine body of the motor is arranged at intervals with the vertical plates.