CN219320318U - Online loading and replacing system for reagent kit - Google Patents

Online loading and replacing system for reagent kit Download PDF

Info

Publication number
CN219320318U
CN219320318U CN202320057847.8U CN202320057847U CN219320318U CN 219320318 U CN219320318 U CN 219320318U CN 202320057847 U CN202320057847 U CN 202320057847U CN 219320318 U CN219320318 U CN 219320318U
Authority
CN
China
Prior art keywords
reagent
outer ring
inner ring
loading
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202320057847.8U
Other languages
Chinese (zh)
Inventor
陈宏�
刘先成
邱亮
王铮
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lifotronic Technology Co ltd
Original Assignee
Lifotronic Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifotronic Technology Co ltd filed Critical Lifotronic Technology Co ltd
Priority to CN202320057847.8U priority Critical patent/CN219320318U/en
Application granted granted Critical
Publication of CN219320318U publication Critical patent/CN219320318U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The utility model relates to the technical field of analyzers, in particular to an online loading and replacing system for a kit. Comprising the following steps: the reagent disk mechanism comprises a reagent disk cover, an outer ring turntable, an inner ring turntable and a reagent pot, wherein the reagent disk cover is provided with an outer ring loading port, an inner ring loading port and an automatic replacement port. The inner ring turntable and the outer ring turntable are matched with each other, so that the reagent boxes on the inner ring turntable and the outer ring turntable can be replaced, the reagent boxes on the inner ring turntable can be manually replaced through the inner ring loading port, the on-line loading and replacing of the reagent boxes without stopping is realized, the operation efficiency of the instrument is improved, and the labor is saved; meanwhile, the on-machine refrigeration of the to-be-on-machine kit is realized.

Description

Online loading and replacing system for reagent kit
Technical Field
The utility model relates to the technical field of analyzers, in particular to an online loading and replacing system for a kit.
Background
At present, in order to meet the test requirements of different types of samples, the full-automatic analyzer needs to store various types of reagents in a reagent disk mechanism at low temperature so as to improve the efficiency of the analyzer, and when the full-automatic analyzer is used, the reagents are sucked from a reagent box in the reagent disk mechanism to carry out mixed reaction with the samples.
All have reagent storehouse and the carousel of setting in the reagent storehouse in the reagent dish mechanism of current full-automatic blood analyzer, load the loading area of carousel with the kit when shut down, the carousel is transported the kit to the suction hole department of reagent storehouse in proper order through the rotation and is carried out the suction of reagent.
However, in the use process of the existing reagent disk mechanism, the emergency detection needs to stop for adding the reagent kit, and needs to stop for replacement after the reagent consumption of part of the reagent kit is finished, so that the efficiency of the instrument is affected, the operation of the instrument needs to be monitored manually, and the customer workload is improved.
Disclosure of Invention
The utility model aims to provide an online loading and replacing system for a kit, which is used for solving the technical problems that the kit to be on-line cannot be placed in a loading area in advance and cannot be replaced online in the prior art.
The utility model provides an online loading and replacing system for a kit, which comprises the following components: the reagent disk mechanism comprises a reagent disk cover, an outer ring turntable, an inner ring turntable and a reagent pot for storing the reagent box at low temperature, wherein the reagent disk cover is arranged in the reagent pot, and the outer ring turntable and the inner ring turntable are both arranged in the reagent pot and can rotate relatively along the same axis;
the reagent disk cover is provided with an outer ring loading port, an inner ring loading port, an automatic replacement port and a reagent suction port, the outer ring loading port and the reagent suction port are both corresponding to the outer ring turntable, the inner ring loading port is corresponding to the inner ring turntable, the automatic replacement port is corresponding to the inner ring turntable and the outer ring turntable, the outer ring loading port is provided with an outer ring cover, the inner ring loading port is provided with an inner ring cover, and the automatic replacement port is provided with a window cover;
the outer ring turntable is circumferentially provided with a plurality of first reagent positions for loading the reagent boxes, and the inner ring turntable is circumferentially provided with a plurality of second reagent positions for loading the reagent boxes.
As a further technical scheme, the reagent disk mechanism further comprises a bottom plate, an inner ring driving device and an outer ring driving device;
The reagent pot is provided with a bottom wall which is fixedly connected with the bottom plate, and a space is arranged between the bottom wall and the bottom plate;
the inner ring driving device and the outer ring driving device are arranged on the bottom plate and are located at the interval, the bottom wall is provided with a through hole, the inner ring driving device penetrates through the through hole to drive the inner ring turntable to rotate, and the outer ring driving device penetrates through the through hole to drive the outer ring turntable to rotate.
As a further technical scheme, the inner ring driving device comprises a main shaft, an inner ring shaft sleeve, an inner ring bearing, an inner ring connecting flange, an inner ring motor, an inner ring synchronous belt wheel and an inner ring driving belt;
one end of the main shaft is fixedly connected to the bottom plate, the other end of the main shaft penetrates through the through hole, the inner ring shaft sleeve is rotationally connected to the main shaft through the inner ring bearing, and the inner ring turntable is connected to the inner ring shaft sleeve through the inner ring connecting flange;
the inner ring motor is fixedly connected to the bottom plate, the inner ring synchronous belt wheel is fixedly connected to the inner ring shaft sleeve, and the output end of the inner ring motor is in transmission connection with the inner ring synchronous belt wheel through the inner ring transmission belt.
As a further technical scheme, the outer ring driving device comprises an outer ring shaft sleeve, an outer ring bearing, an outer ring connecting flange, an outer ring motor, an outer ring synchronous pulley, an outer ring transmission belt and an outer ring reduction gear;
the outer ring shaft sleeve is rotationally connected with the inner ring shaft sleeve through the outer ring bearing, and the outer ring turntable is connected with the outer ring shaft sleeve through the outer ring connecting flange;
the outer ring motor is fixedly connected to the bottom plate, the outer ring synchronous pulley is fixedly connected to the outer ring shaft sleeve, the output end of the outer ring motor is in transmission connection with the outer ring reduction gear, and the outer ring reduction gear is in transmission connection with the outer ring synchronous pulley through the outer ring transmission belt.
As a further technical scheme, the reagent disk mechanism further comprises an inner ring code disk, an inner ring zero position optocoupler, an inner ring code tooth optocoupler, an outer ring code disk, an outer ring zero position optocoupler and an outer ring code tooth optocoupler;
the inner ring connecting flange is connected to the upper end of the inner ring shaft sleeve, the inner ring code disc is connected to the lower end of the inner ring shaft sleeve, and the inner ring zero position optocoupler and the inner ring code tooth optocoupler are both connected to the bottom plate and matched with the inner ring code disc;
The outer ring connecting flange is connected to the upper end of the outer ring shaft sleeve, the outer ring code disc is connected to the lower end of the outer ring shaft sleeve, and the outer ring zero position optocoupler and the outer ring code tooth optocoupler are both connected to the bottom plate and matched with the outer ring code disc.
As a further technical scheme, the reagent kit further comprises an outer ring RFID reader and an inner ring RFID reader, wherein the outer ring RFID reader is arranged in the reagent pot and used for reading the RFID information of the reagent kit on the first reagent position, and the inner ring RFID reader is arranged outside the reagent disc mechanism and used for reading the RFID information of the reagent kit on the second reagent position.
As a further technical scheme, the automatic window opening and closing device further comprises an automatic window opening and closing mechanism, wherein the automatic window opening and closing mechanism is used for driving the window cover to automatically close or open the automatic replacement opening.
As a further technical scheme, the automatic window opening and closing mechanism comprises an auxiliary guide rail, a first motor, a crank, a connecting rod, a linear guide rail, a limiting baffle and a limiting optocoupler;
the auxiliary guide rail and the linear guide rail are oppositely arranged and are both fixed on the reagent tray cover, the first motor is fixed on the reagent tray cover and is connected with the crank, one end of the connecting rod is hinged with the window cover, the other end of the connecting rod is hinged with the crank, the limiting baffle is arranged on the crank, and the limiting optocoupler is arranged on the reagent tray cover and is matched with the limiting baffle.
As a further technical scheme, the reagent kit further comprises a carrying mechanism and a clamping mechanism, wherein the clamping mechanism is used for clamping the reagent kit, and the carrying mechanism is used for driving the clamping mechanism to move between the first reagent position and the second reagent position.
As a further technical scheme, the clamping mechanism comprises a driving device, a front clamping jaw, a rear clamping jaw, a cam, a roller and a return spring;
front clamping jaw with back clamping jaw sets up relatively, just front clamping jaw with all be provided with on the back clamping jaw the running roller, the cam sets up in two between the running roller, drive arrangement is used for the drive the cam rotates, the cam drives through rotating two front clamping jaw with back clamping jaw is kept away from each other, reset spring's one end connect in front clamping jaw, the other end connect in back clamping jaw, just reset spring is used for driving front clamping jaw with back clamping jaw is close to each other.
As a further technical scheme, be provided with first location portion on the kit, preceding clamping jaw with all be provided with on the back clamping jaw with the second location portion of first location portion cooperation location.
As a further technical scheme, the conveying mechanism comprises a transverse conveying device and a longitudinal conveying device;
the transverse handling device is connected to the reagent tray cover through a supporting piece, the longitudinal handling device is connected to the transverse handling device, and the clamping mechanism is connected to the longitudinal handling device.
As a further technical scheme, the conveying mechanism further comprises a transverse in-place buffer device and a transverse in-place detection device which are arranged on the transverse conveying device, and a longitudinal in-place buffer device and a longitudinal in-place detection device which are arranged on the longitudinal conveying device.
As a further technical scheme, the reagent disk mechanism further comprises a mixing device arranged in the reagent pot, and the mixing device is used for mixing the reagent box.
As a further technical scheme, reagent dish mechanism still including set up in on the reagent pot inside wall and be used for with kit complex retaining ring, be provided with the breach on the retaining ring, the breach with automatic change mouth corresponds.
As a further technical scheme, one side of kit is provided with the shell fragment, and the opposite side is provided with the buckle, first reagent position with the second reagent position is the slot, just the slot has relative first lateral wall and second lateral wall, first lateral wall be used for with shell fragment cooperation butt, the second lateral wall be used for with buckle cooperation joint.
Compared with the prior art, the on-line loading and replacing system for the kit has the technical advantages that:
the utility model provides an on-line loading and replacing system for a kit, which comprises the following components: the reagent disk mechanism comprises a reagent disk cover, an outer ring turntable, an inner ring turntable and a reagent pot for storing the reagent box at low temperature, wherein the reagent disk cover is arranged on the reagent pot, and the outer ring turntable and the inner ring turntable are arranged in the reagent pot and can rotate relatively along the same axis; the reagent disk cover is provided with an outer ring loading port, an inner ring loading port, an automatic replacement port and a reagent suction port, the outer ring loading port and the reagent suction port are corresponding to the outer ring turntable, the inner ring loading port is corresponding to the inner ring turntable, the automatic replacement port is corresponding to the inner ring turntable and the outer ring turntable, the outer ring loading port is provided with an outer ring cover, the inner ring loading port is provided with an inner ring cover, and the automatic replacement port is provided with a window cover; the outer ring carousel is provided with a plurality of first reagent positions that are used for loading the kit along circumference, and the inner ring carousel is provided with a plurality of second reagent positions that are used for loading the kit along circumference.
During the use, outer lane carousel rotates, load the first reagent position with the kit that waits to inhale through outer lane load port, the inner circle carousel rotates, load the second reagent position with the kit that waits to go up through the inner circle load port, and at least one second reagent position is empty, when the kit on the first reagent position is inhaled empty and need be changed, open automatic change mouth, change the kit that is inhaled empty on the first reagent position through outer lane carousel and change mouthful department automatically, change empty second reagent position through the inner circle carousel to automatic change mouthful department, load the kit that is inhaled empty on the first reagent position to empty second reagent position department, rethread inner circle carousel changes the same kit that waits to go up of detection item to automatic change mouthful department, carry the same kit that waits to go up of detection item and load to empty first reagent position, accomplish the kit that waits to go up and be inhaled empty and change, the online instrument's of having realized not stopping operation efficiency, the manpower is saved.
Meanwhile, as the outer ring turntable and the inner ring turntable can rotate independently, when the outer ring turntable works, the reagent kit on the second reagent position can be manually replaced through the inner ring loading port, the loading and replacement of the reagent kit on the second reagent position without stopping the machine on line are realized, the running efficiency of the instrument is improved, the workload of a user is reduced, the reagent kit to be sucked and the reagent kit to be put on the machine can be stored at a low temperature in the reagent pot at the same time, the on-machine refrigeration of the reagent kit to be put on the machine is realized, the workload of the user is further reduced, and the use experience is improved.
Additional features and advantages of the utility model will be set forth in the detailed description which follows.
Drawings
In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are needed in the description of the embodiments or the prior art will be briefly described, and it is obvious that the drawings in the description below are some embodiments of the present utility model, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of an online loading and replacing system for a kit according to an embodiment of the present utility model;
FIG. 2 is a schematic diagram of a mechanism structure of a reagent disk according to an embodiment of the present utility model;
FIG. 3 is a schematic view of a reagent disk mechanism when a reagent disk cover provided in an embodiment of the present utility model is opened;
FIG. 4 is a schematic structural diagram of a kit according to an embodiment of the present utility model;
FIG. 5 is an isometric view of a reagent disk mechanism provided by an embodiment of the present utility model;
FIG. 6 is a cross-sectional view of a reagent disk mechanism provided by an embodiment of the present utility model;
FIG. 7 is an enlarged view of FIG. 6A according to an embodiment of the present utility model;
FIG. 8 is an enlarged view of FIG. 6B according to an embodiment of the present utility model;
FIG. 9 is a schematic diagram of a retainer ring according to an embodiment of the present utility model;
FIG. 10 is a schematic view of the inner ring turntable and the outer ring turntable of the reagent disk mechanism according to the embodiment of the present utility model;
FIG. 11 is an exploded view of an inner race drive and an outer race drive according to an embodiment of the present utility model;
fig. 12 is a schematic structural diagram of one side of a clamping mechanism according to an embodiment of the present utility model;
fig. 13 is a schematic structural view of the other side of the clamping mechanism according to the embodiment of the present utility model;
FIG. 14 is a partial exploded view of a clamping mechanism provided in an embodiment of the present utility model;
fig. 15 is a schematic transmission diagram of a clamping mechanism according to an embodiment of the present utility model;
FIG. 16 is a schematic diagram showing the cam-to-roller position comparison of three states of open, clamped and clamped of the clamping mechanism provided by the embodiment of the utility model;
FIG. 17 is a schematic diagram showing a comparison of the positions of the front and rear jaws of the clamping mechanism in three states of open, clamped and empty;
fig. 18 is a schematic structural diagram of a handling mechanism according to an embodiment of the present utility model;
FIG. 19 is an exploded view of a longitudinal handling apparatus according to an embodiment of the present utility model;
FIG. 20 is a schematic diagram of a longitudinal in-place buffer device and a longitudinal in-place detection device according to an embodiment of the present utility model;
FIG. 21 is a position comparison diagram of three states of lifting, grabbing and in-place buffering of a longitudinal handling device according to an embodiment of the present utility model;
FIG. 22 is a diagram showing the state of the longitudinal driving plate and the longitudinal limiting pin in close contact and in release according to the embodiment of the present utility model;
FIG. 23 is an exploded view of a lateral handling device according to an embodiment of the present utility model;
FIG. 24 is a diagram showing a state of the snap-fit and release of the kit according to the embodiment of the present utility model;
FIG. 25 is a diagram showing a comparison of the fit state of the elastic sheet and the outer ring turntable during the removal process of the kit according to the embodiment of the present utility model;
FIG. 26 is a diagram showing two state comparisons during the in-place buffering of the transverse handling device according to the embodiment of the present utility model;
FIG. 27 is a schematic view of a closed state of an automatic window opening and closing mechanism according to an embodiment of the present utility model;
FIG. 28 is a schematic view of an open state of an automatic window opening and closing mechanism according to an embodiment of the present utility model;
fig. 29 is a schematic diagram of a clamping mechanism for clamping a kit on an inner ring turntable to an inner ring RFID reader according to an embodiment of the present utility model.
Icon: 1-a reagent disk mechanism; 2-a carrying mechanism; 3-a clamping mechanism; 4-an automatic window opening and closing mechanism; 5-reagent tray cover; 6-an outer ring turntable; 7-an inner ring turntable; 8-a reagent pot; 9-an outer ring loading port; 10-an inner ring loading port; 11-automatic replacement port; 12-reagent suction port; 13-an outer ring cover; 14-an inner ring cover; 15-a first reagent site; 16-a second reagent site; 17-a bottom plate; 18-a bottom wall; 19-a main shaft; 20-an inner ring sleeve; 21-an inner ring bearing; 22-an inner ring connecting flange; 23-an inner ring motor; 24-an inner ring synchronous pulley; 25-an inner ring transmission belt; 26-an outer ring sleeve; 27-an outer ring bearing; 28-an outer ring connecting flange; 29-an outer ring motor; 30-an outer ring synchronous pulley; 31-an outer ring transmission belt; 32-an outer ring reduction gear; 33-an inner ring code wheel; 34-lower end face; 35-an outer ring flange nut; 36-an outer ring code disc; 37-outer ring zero position optocoupler; 38-an outer ring code tooth optocoupler; 39-an outer ring RFID reader; 40-inner ring RFID reader; 41-window covers; 42-auxiliary guide rails; 43-a first motor; 44-crank; 45-connecting rod; 46-linear guide rail; 47-limiting baffle plates; 48-limiting optocouplers; 49-front clamping jaw; 50-rear clamping jaw; 51-cam; 52-a return spring; 53-a transverse handling device; 54-longitudinal handling device; 55-check ring; 56-notch; 57-shrapnel; 58-snap; 59-sidewalls; 60-a bottom insulation layer; 61-an outer ring heat preservation layer; 62-an inner ring heat preservation layer; 63-a motor bracket; 64-a second motor; 65-a motor mounting plate; 66-front connecting frame; 67-rear connection rack; 68-clamping the guide rail; 69-a scratch detection optocoupler; 70-catching a hollow detection baffle; 71-clamping jaw zero position optocoupler; 72-clamping jaw zero stop piece; 73-clamping the bottom plate; 74-positioning a spring; 75-pressing a box frame; 76-roller; 77-roller shaft; 78-kit; 79-reagent bottle holder; 80-a first reagent bottle; 81-a second reagent bottle; 82-magnetic bead bottle; 83-mixing gear support columns; 84-transverse belt press plate; 85-positioning the clamping holes; 86-clamping nail; 87-struts; 88-a longitudinal motor assembly; 89-a longitudinal floor; 90-a longitudinal synchronous belt; 91-a longitudinal driven wheel assembly; 92-driving the plate longitudinally; 93-longitudinal linear guide rail; 94-a longitudinal slide mounting plate; 95-loading a linear rail longitudinally; 96-longitudinal belt press plate; 97-longitudinal zero optocoupler; 98-longitudinal zero stop; 99-detecting a baffle in place longitudinally; 100-detecting an optocoupler in place longitudinally; 101-a longitudinal limiting pin; 102-loading a spring longitudinally; 103-a transverse motor assembly; 104-a transverse bottom plate; 105-transverse synchronous belt; 106-a transverse driven wheel assembly; 107-a transverse driving plate; 108-a transverse linear guide rail; 109-a transverse slider mounting plate; 110-loading a linear rail transversely; 111-a transverse zero optocoupler; 112-a transverse zero stop; 113-a transverse in-place detection optocoupler; 114-a transverse limiting pin; 115-transverse loading spring; 116-sector mixing gear.
Detailed Description
The technical solutions of the present utility model will be clearly and completely described in connection with the embodiments, and it is apparent that the described embodiments are some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
In the description of the present utility model, it should be noted that the directions or positional relationships indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.
In addition, the technical solutions of the embodiments may be combined with each other, but it is necessary to base that the technical solutions can be realized by those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should be considered to be absent and not within the scope of protection claimed in the present utility model.
The utility model will now be described in further detail by way of specific examples of embodiments in connection with the accompanying drawings.
The specific structure is shown in fig. 1 to 29.
The embodiment provides an online loading and replacing system for a kit, which comprises: the reagent disk mechanism 1, the reagent disk mechanism 1 comprises a reagent disk cover 5, an outer ring turntable 6, an inner ring turntable 7 and a reagent pot 8 for storing a reagent box 78 at low temperature, the reagent disk cover 5 is covered on the reagent pot 8, and the outer ring turntable 6 and the inner ring turntable 7 are both arranged in the reagent pot 8 and can rotate relatively along the same axis; the reagent disk cover 5 is provided with an outer ring loading port 9, an inner ring loading port 10, an automatic replacing port 11 and a reagent suction port 12, wherein the outer ring loading port 9 and the reagent suction port 12 are corresponding to the outer ring turntable 6, the inner ring loading port 10 is corresponding to the inner ring turntable 7, the automatic replacing port 11 is corresponding to the inner ring turntable 7 and the outer ring turntable 6, the outer ring loading port 9 is provided with an outer ring cover 13, the inner ring loading port 10 is provided with an inner ring cover 14, and the automatic replacing port 11 is provided with a window cover 41; the outer ring turntable 6 is provided with a plurality of first reagent places 15 for loading reagent cartridges 78 in the circumferential direction, and the inner ring turntable 7 is provided with a plurality of second reagent places 16 for loading reagent cartridges 78 in the circumferential direction.
In this embodiment, when in use, the outer ring turntable 6 rotates, the to-be-sucked reagent kit 78 is loaded to the first reagent position 15 through the outer ring loading port 9, the inner ring turntable 7 rotates, the to-be-sucked reagent kit 78 is loaded to the second reagent position 16 through the inner ring loading port 10, and at least one second reagent position 16 is empty, when the to-be-sucked reagent kit 78 on the first reagent position 15 needs to be replaced, the automatic replacement port 11 is opened, the to-be-sucked reagent kit 78 on the first reagent position 15 is transferred to the automatic replacement port 11 through the outer ring turntable 6, the to-be-sucked reagent kit 78 on the first reagent position 15 is loaded to the empty second reagent position 16, the to-be-sucked reagent kit 78 with the same detection items is transferred to the automatic replacement port 11 through the inner ring turntable 7, the to-be-sucked reagent kit 78 with the same detection items is carried and loaded to the empty first reagent position 15, the on-line replacement of the to-be-sucked reagent kit 78 is completed, the operation efficiency of the instrument is improved, and the labor is saved.
Meanwhile, as the outer ring turntable 6 and the inner ring turntable 7 can rotate independently, when the outer ring turntable 6 works, the reagent box 78 on the second reagent position 16 can be manually replaced through the inner ring loading port 10, the loading and replacement of the reagent box 78 on the second reagent position 16 without stopping the machine on line are realized, the operation efficiency of an instrument is improved, the workload of a user is reduced, the reagent box 78 to be sucked and the reagent box 78 to be on-line can be stored at a low temperature in the reagent pot 8 at the same time, a set of refrigerating system is shared, the on-line refrigeration of the reagent box 78 to be on-line is realized, the workload of the user is further reduced, and the use experience is improved.
In the alternative solution of this embodiment, the automatic opening and closing window mechanism 4 is further included, and the automatic opening and closing window mechanism 4 is used for driving the window cover 41 to automatically close or open the automatic replacement opening 11. Automatic opening and closing and automatic replacement of the opening 11 are achieved, automation is improved, and labor is saved.
In an alternative embodiment of the present embodiment, the reagent kit further comprises a handling mechanism 2 and a clamping mechanism 3, wherein the clamping mechanism 3 is used for clamping the reagent kit 78, and the handling mechanism 2 is used for driving the clamping mechanism 3 to move between the first reagent site 15 and the second reagent site 16. Through the setting of transport mechanism 2 and fixture 3, can on-line automatic loading change kit 78, further improve the operating efficiency of instrument to and improve automation and practice thrift the manpower.
When the automatic reagent box loading machine is used, the outer ring turntable 6 rotates, the reagent box 78 to be sucked is loaded to the first reagent position 15 through the outer ring loading port 9, the inner ring turntable 7 rotates, the reagent box 78 to be loaded is loaded to the second reagent position 16 through the inner ring loading port 10, at least one second reagent position 16 is empty, when the reagent box 78 on the first reagent position 15 is sucked and needs to be replaced, the automatic replacement port 11 is opened by the automatic opening and closing window mechanism 4, the reagent box 78 sucked on the first reagent position 15 is transferred to the automatic replacement port 11 through the outer ring turntable 6, the empty second reagent position 16 is transferred to the automatic replacement port 11 through the inner ring turntable 7, the clamping mechanism 3 is driven to move to the first reagent position 15 corresponding to the automatic replacement port 11 by the clamping mechanism 2, the sucked reagent box 78 is clamped by the clamping mechanism 3, the clamping mechanism 3 is driven to move to the second reagent position 16 corresponding to the automatic replacement port 11 and empty, after the sucked reagent box 78 is loaded to the empty second reagent position 16, the reagent box 78 is transferred to the automatic replacement port 7 through the inner ring turntable 7, the reagent box 78 to be detected on the same item to be detected is transferred to the automatic replacement port 11, the reagent box 78 is stopped on the automatic replacement machine, and the reagent box 78 is not stopped at the automatic replacement port 2, and the reagent box 78 is stopped at the position 3.
In this embodiment, the carrying mechanism 2 is disposed outside the reagent disk mechanism 1, where the carrying mechanism 2 may be fixed on one side of the reagent disk mechanism 1 through a bearing frame or a bearing seat, and at this time, the reagent disk mechanism 1 and the carrying mechanism 2 are separately disposed, so that the installation and maintenance are convenient, and the position of the carrying mechanism 2 is convenient to be replaced according to specific requirements; however, the present embodiment is not limited to this, and the carrying mechanism 2 may be provided on the reagent tray cover 5, so that the overall occupied space is reduced, and the overall integration level is improved.
In an alternative technical scheme of the embodiment, the reagent disk mechanism 1 further comprises a bottom plate 17, an inner ring driving device and an outer ring driving device; the reagent pot 8 is provided with a bottom wall 18, the bottom wall 18 is fixedly connected with the bottom plate 17, and a space is arranged between the bottom wall 18 and the bottom plate 17; the inner ring driving device and the outer ring driving device are both arranged on the bottom plate 17 and are both positioned at intervals, the bottom wall 18 is provided with a through hole, the inner ring driving device penetrates through the through hole to drive the inner ring turntable 7 to rotate, and the outer ring driving device penetrates through the through hole to drive the outer ring turntable 6 to rotate.
In this embodiment, the reagent pot 8 is provided with refrigerating system and is used for making reagent pot 8 can the low temperature save kit 78, the diapire 18 outside of reagent pot 8 is provided with bottom heat preservation 60, the lateral wall 59 outside of reagent pot 8 is provided with outer lane heat preservation 61, the through-hole department is provided with inner circle heat preservation 62, bottom heat preservation 60, outer lane heat preservation 61 and inner circle heat preservation 62 all are used for reducing the inside and outside heat exchange of reagent pot 8, guarantee to be in the low temperature state in the reagent pot 8, wherein, bottom heat preservation 60, outer lane heat preservation 61 and inner circle heat preservation 62 are made by insulation material, preferably, bottom heat preservation 60, outer lane heat preservation 61 and inner circle heat preservation 62 are the heat preservation cotton, the cost is lower and the heat preservation is effectual.
In this embodiment, the diapire 18 of reagent pot 8 passes through support piece fixed connection on bottom plate 17, and support piece with reagent pot 8 prop up and form the interval between bottom plate 17, inner circle drive arrangement and outer lane drive arrangement all set up in the interval department, improve space utilization and conveniently independently control respectively through control module and drive inner circle carousel 7 and outer lane carousel 6 operation, realize automatic operation.
In an alternative technical scheme of the embodiment, the inner ring driving device comprises a main shaft 19, an inner ring shaft sleeve 20, an inner ring bearing 21, an inner ring connecting flange 22, an inner ring motor 23, an inner ring synchronous pulley 24 and an inner ring driving belt 25; one end of the main shaft 19 is fixedly connected to the bottom plate 17, the other end of the main shaft 19 is penetrated through the through hole, the inner ring shaft sleeve 20 is rotationally connected to the main shaft 19 through the inner ring bearing 21, and the inner ring turntable 7 is connected to the inner ring shaft sleeve 20 through the inner ring connecting flange 22; the inner ring motor 23 is fixedly connected to the bottom plate 17, the inner ring synchronous pulley 24 is fixedly connected to the inner ring shaft sleeve 20, and the output end of the inner ring motor 23 is in transmission connection with the inner ring synchronous pulley 24 through the inner ring transmission belt 25.
In this embodiment, the inner ring driving device uses the bottom plate 17 as a carrier, fixedly connects the main shaft 19 on the bottom plate 17, connects and supports the inner ring shaft sleeve 20 and the main shaft 19 through the inner ring bearing 21, the lower end of the inner ring shaft sleeve 20 is fixedly connected with the inner ring synchronous pulley 24, the inner ring motor 23 drives the inner ring synchronous pulley 24 to rotate around the main shaft 19 through the inner ring transmission belt 25, the inner ring shaft sleeve 20 moves along with the inner ring synchronous pulley 24 in a circular manner, and then drives the inner ring turntable 7 to rotate through the inner ring connecting flange 22. The whole structure is simple, and the transmission effect is stable and reliable.
In an alternative technical scheme of the embodiment, the outer ring driving device comprises an outer ring shaft sleeve 26, an outer ring bearing 27, an outer ring connecting flange 28, an outer ring motor 29, an outer ring synchronous pulley 30, an outer ring transmission belt 31 and an outer ring reduction gear 32; the outer ring shaft sleeve 26 is rotatably connected to the inner ring shaft sleeve 20 through an outer ring bearing 27, and the outer ring turntable 6 is connected to the outer ring shaft sleeve 26 through an outer ring connecting flange 28; the outer ring motor 29 is fixedly connected to the bottom plate 17, the outer ring synchronous pulley 30 is fixedly connected to the outer ring shaft sleeve 26, the output end of the outer ring motor 29 is in transmission connection with the outer ring reduction gear 32, and the outer ring reduction gear 32 is in transmission connection with the outer ring synchronous pulley 30 through the outer ring transmission belt 31.
In this embodiment, the outer ring driving device uses the inner ring shaft sleeve 20 as a carrier, the outer ring shaft sleeve 26 and the inner ring shaft sleeve 20 are connected and supported by a bearing, the outer ring connecting flange 28 is connected with the outer ring shaft sleeve 26 by an outer ring flange nut 35, the lower end of the outer ring shaft sleeve 26 is fixedly connected with an outer ring synchronous pulley 30, the outer ring motor 29 drives the outer ring synchronous pulley 30 to rotate around the main shaft 19 by an outer ring driving belt 31 after one-stage speed reduction of an outer ring reduction gear 32, and the outer ring shaft sleeve 26 moves along with the outer ring synchronous pulley 30 in a circular manner, and then drives the outer ring turntable 6 to rotate by the outer ring connecting flange 28. The whole structure is simple, the transmission effect is stable and reliable, and simultaneously, the outer ring driving device and the inner ring driving device are integrated with the main shaft 19, so that the occupied space is reduced.
In an alternative technical solution of the embodiment, the reagent disk mechanism 1 further includes an inner ring code disk 33, an inner ring zero position optocoupler, an inner ring code tooth optocoupler, an outer ring code disk 36, an outer ring zero position optocoupler 37 and an outer ring code tooth optocoupler 38; the inner ring connecting flange 22 is connected to the upper end of the inner ring shaft sleeve 20, the inner ring code disc 33 is connected to the lower end of the inner ring shaft sleeve 20, and the inner ring zero position optical coupler and the inner ring code tooth optical coupler are both connected to the bottom plate 17 and matched with the inner ring code disc 33; the outer ring connecting flange 28 is connected to the upper end of the outer ring shaft sleeve 26, the outer ring code disc 36 is connected to the lower end of the outer ring shaft sleeve 26, and the outer ring zero position optocoupler 37 and the outer ring code tooth optocoupler 38 are both connected to the bottom plate 17 and matched with the outer ring code disc 36.
In this embodiment, the inner ring connecting flange 22 and the outer ring connecting flange 28 are made of non-heat-conductive materials and are respectively disposed on the upper end surface of the inner ring sleeve 20 and the upper end surface of the outer ring sleeve 26, so that heat transfer to the outer ring turntable 6 and the inner ring turntable 7 is effectively reduced. Meanwhile, an inner ring code wheel 33 is fixedly connected to the lower end of the inner ring shaft sleeve 20 and is matched with an inner ring zero position optical coupler and an inner ring code tooth optical coupler, wherein the inner ring zero position optical coupler and the inner ring code tooth optical coupler are respectively fixed on the bottom plate 17 through fixing frames, the inner ring zero position optical coupler and the inner ring code wheel 33 are matched to be used for positioning the initial position of the inner ring turntable 7, namely positioning the first second reagent position 16, and the inner ring code tooth optical coupler and the inner ring code wheel 33 are matched to ensure the movement precision of the inner ring turntable 7, so that the second reagent position 16 can accurately correspond to the automatic replacement port 11. The lower end of the outer ring shaft sleeve 26 is fixedly connected with an outer ring code wheel 36 and is matched with an outer ring zero position optocoupler 37 and an outer ring code tooth optocoupler 38, wherein the outer ring zero position optocoupler 37 and the outer ring code tooth optocoupler 38 are respectively fixed on the bottom plate 17 through fixing frames, the outer ring zero position optocoupler 37 and the outer ring code wheel 36 are matched to be used for positioning the initial position of the outer ring turntable 6, namely positioning the first reagent position 15, and the outer ring code tooth optocoupler 38 and the outer ring code wheel 36 are matched to ensure the movement precision of the outer ring turntable 6, so that the first reagent position 15 can accurately correspond to the automatic replacement port 11.
In an alternative solution of this embodiment, the reagent kit further includes an outer ring RFID reader 39 and an inner ring RFID reader 40, where the outer ring RFID reader 39 is disposed in the reagent pot 8 and is used for reading RFID information of the reagent kit 78 on the first reagent site 15, and the inner ring RFID reader 40 is disposed on the reagent disk cover 5 and is used for reading RFID information of the reagent kit 78 on the second reagent site 16.
In this embodiment, the outer ring RFID reader 39 and the inner ring RFID reader 40 are both components for reading the RFID code on the end face of the reagent kit 78, the RFID information of the reagent kit 78 to be sucked on the first reagent bit 15 is read by the outer ring RFID reader 39 and matched with the corresponding first reagent bit 15, the RFID information of the reagent kit 78 to be on machine on the second reagent bit 16 is read by the inner ring RFID reader 40 and matched with the corresponding second reagent bit 16, and the accuracy of replacement of the reagent kit 78 on the first reagent bit 15 and the reagent kit 78 on the second reagent bit 16 is ensured, and meanwhile, the accuracy of integral operation is ensured.
In the alternative technical scheme of the embodiment, the automatic window opening and closing mechanism 4 can be fixed on one side of the reagent disk mechanism 1 through a bearing frame or a bearing seat, and at the moment, the reagent disk mechanism 1 and the carrying mechanism 2 are arranged in a split manner, so that the installation and the maintenance are convenient; preferably, the automatic opening and closing window mechanism 4 is arranged on the reagent tray cover 5, so that the whole occupied space is reduced, and the whole integration level is improved. Specifically, the automatic window opening and closing mechanism 4 includes an auxiliary guide rail 42, a first motor 43, a crank 44, a connecting rod 45 and a linear guide rail 46, the auxiliary guide rail 42 and the linear guide rail 46 are oppositely arranged and are both fixed on the reagent disk cover 5, the auxiliary guide rail 42 is located at one end of the automatic replacement port 11 close to the outer ring turntable 6, the linear guide rail 46 is located at one end of the automatic replacement port 11 close to the inner ring turntable 7, the outer ring RFID reader 39 is fixed on the reagent disk cover 5 and is located at the auxiliary guide rail 42, the first motor 43 is fixed on the reagent disk cover 5 through a motor bracket 63, the output end of the first motor 43 is connected with the crank 44, one end of the connecting rod 45 is hinged with the window cover 41, the other end of the connecting rod 45 is hinged with one end of the crank 44, a limiting stop piece 47 is arranged at the other end of the crank 44, the reagent disk cover 5 is provided with a limiting optocoupler 48, and the limiting stop piece 47 is matched with the limiting optocoupler 48 to limit the rotation angle of the first motor 43, so that the first motor 43 can accurately open or close the automatic replacement port 11 through the crank 44. The whole structure of the first driving device is simple and compact, the occupied space is small, the driving is stable and accurate, meanwhile, the two ends of the connecting rod 45 are hinged, and clamping can be effectively avoided.
Wherein, when the need for replacing the reagent kit 78 exists, the crank 44 rotates along with the output end of the first motor 43, the driving connecting rod 45 moves to push/pull the window cover 41 to reciprocate along the linear guide rail 46 and the auxiliary guide rail 42, and meanwhile, when the need for replacing the reagent kit 78 does not exist, the automatic replacing port 11 is kept closed, and the reagent pot 8 is insulated.
In an alternative solution of the present embodiment, the clamping mechanism 3 comprises a driving device, a front clamping jaw 49, a rear clamping jaw 50, a cam 51, a roller and a return spring 52; the front clamping jaw 49 and the rear clamping jaw 50 are oppositely arranged, rollers are arranged on the front clamping jaw 49 and the rear clamping jaw 50, a cam 51 is arranged between the two rollers, a driving device is used for driving the cam 51 to rotate, the cam 51 drives the two rollers to drive the front clamping jaw 49 and the rear clamping jaw 50 to be away from each other through rotation, one end of a reset spring 52 is connected with the front clamping jaw 49, the other end of the reset spring 52 is connected with the rear clamping jaw 50, and the reset spring 52 is used for driving the front clamping jaw 49 and the rear clamping jaw 50 to be close to each other.
In this embodiment, the cam 51 is connected with two rollers through the cam pair, and drive arrangement rotates through drive cam 51, makes two rollers keep away from relatively to drive preceding clamping jaw 49 and back clamping jaw 50 to open, and the pulling force effect of reset spring 52 drives preceding clamping jaw 49 and back clamping jaw 50 and resets and press from both sides tightly, and then realizes that preceding clamping jaw 49 and back clamping jaw 50 press from both sides the function of putting kit 78, simple structure, and the drive is convenient and press from both sides and put stably, and cam 51 and two rollers cooperation drive simultaneously avoid driving the card to be in touch, improve stability.
Specifically, the driving device includes a second motor 64, a motor mounting plate 65, a front connecting frame 66, a rear connecting frame 67, a clamping guide rail 68, a grabbing empty detection optocoupler 69, grabbing empty detection baffle 70, a clamping jaw zero position optocoupler 71, a clamping jaw zero position baffle 72, a clamping bottom plate 73, a positioning spring 74 and a box pressing frame 75, wherein the second motor 64 is mounted on the upper side of the clamping bottom plate 73 through the motor mounting plate 65, the clamping guide rail 68 is mounted on the lower side of the clamping bottom plate 73, the clamping guide rail 68 is provided with a pair of clamping guide rails, the front clamping jaw 49 is slidably connected between the pair of clamping guide rails 68 through the front connecting frame 66, the rear clamping jaw 50 is slidably connected between the pair of clamping guide rails 68 through the rear connecting frame 67, rollers comprise rollers 76 and roller shafts 77, the roller shafts 77 of the two rollers are respectively connected on the front connecting frame 66 and the rear connecting frame 67, the cam 51 is located between the rollers 76 of the two rollers, the cam 51 is connected with the roller 76 in a cam pair of the cam 51, the clamping jaw optocoupler 71 is arranged on the clamping bottom plate 73, the zero position baffle 72 is arranged on the upper end of the cam 51, the zero position baffle 71 is matched with the motor zero position baffle 71, the second clamping jaw 50 can rotate by the second clamping jaw 50, and the second clamping jaw 50 can rotate by the precision angle of the front clamping jaw 50 and the second clamping jaw 50.
The grabbing empty detection optocoupler 69 is arranged on the clamping bottom plate 73, the grabbing empty detection baffle 70 is arranged on the rear connecting frame 67, when the front clamping jaw 49 and the rear clamping jaw 50 are in an open state, the distance between the grabbing empty detection optocoupler 69 and the front end of the grabbing empty detection baffle 70 is a, and the grabbing empty detection baffle 70 does not shield the grabbing empty detection optocoupler 69; when the front clamping jaw 49 and the rear clamping jaw 50 are in a clamping state, the distance between the grab-empty detection optocoupler 69 and the front end of the grab-empty detection baffle 70 is b, and the grab-empty detection baffle 70 does not shield the grab-empty detection optocoupler 69; when the front clamping jaw 49 and the rear clamping jaw 50 are in a grabbing state, the distance between the grabbing detection optocoupler 69 and the front end of the grabbing detection baffle 70 is c, and the grabbing detection baffle 70 shields the grabbing detection optocoupler 69; by matching the scratch detection optocoupler 69 with the scratch detection blocking piece 70, the scratch accuracy is ensured, and the scratch is avoided.
The two ends of the positioning spring 74 are respectively connected with the clamping bottom plate 73 and the rear connecting frame 67 through positioning frames, and the rear clamping jaw 50 is positioned through the positioning spring 74, so that the stability and the accuracy of clamping and placing are improved; the pressing frame 75 is disposed on the rear clamping jaw 50 and located between the front clamping jaw 49 and the rear clamping jaw 50, and is used for cooperatively grabbing the reagent kit 78, so as to avoid the reagent kit 78 from tilting when the reagent kit 78 is grabbed.
In an alternative solution of this embodiment, the reagent kit 78 is provided with a first positioning portion, and the front clamping jaw 49 and the rear clamping jaw 50 are provided with second positioning portions that cooperate with the first positioning portion for positioning.
In this embodiment, the kit 78 includes a reagent bottle support 79, a first reagent bottle 80, a second reagent bottle 81 and a magnetic bead bottle 82, the first reagent bottle 80 and the second reagent bottle 81 are clamped on the reagent bottle support 79, the magnetic bead bottle 82 is rotationally connected on the reagent bottle support 79, one side of the reagent bottle support 79 is provided with a spring plate 57, the opposite side is provided with a buckle 58, and the reagent bottle support 79 is further provided with a first positioning part; when the front clamping jaw 49 and the rear clamping jaw 50 clamp the reagent kit 78, the second positioning parts on the front clamping jaw 49 and the rear clamping jaw 50 are matched with the first positioning parts on the reagent bottle support 79 to position, so that the grabbing stability of the reagent kit 78 is ensured, and slipping is avoided. It should be noted that the reagent bottle support 79 is not limited to the first reagent bottle 80 and the second reagent bottle 81, and other reagent bottles may be provided, that is, the number of the reagent bottles may be set according to the requirement.
The preferred embodiment of this embodiment, first location portion is the location centre gripping hole 85 of setting on reagent bottle support 79, and the second location portion is centre gripping nail 86, simple structure and location are effectual, and further, location centre gripping hole 85 and centre gripping nail 86 all are provided with a plurality ofly, and the one-to-one, further improves the stability of centre gripping.
In an alternative solution of the present embodiment, the handling mechanism 2 comprises a transverse handling device 53 and a longitudinal handling device 54; the traverse transporting device 53 is connected to the reagent disk cover 5 via a strut 87, the longitudinal transporting device 54 is connected to the traverse transporting device 53, and the gripping mechanism 3 is connected to the longitudinal transporting device 54. The transverse direction is the horizontal direction, the longitudinal direction is the vertical direction, namely the Z-axis carrying mechanism 2 can reciprocate up and down, the X-axis carrying mechanism 2 can reciprocate along the radial direction of the inner ring turntable 7, and longitudinal and transverse power is provided for carrying the reagent kit 78 by the clamping mechanism 3. The transverse conveying device 53 and the longitudinal conveying device 54 are used for conveying step by step, so that the conveying stability and accuracy are ensured.
Specifically, the carrying mechanism 2 further includes a longitudinal in-place buffer device and a longitudinal in-place detection device, wherein the longitudinal carrying device 54 includes a longitudinal motor assembly 88, a longitudinal bottom plate 89, a longitudinal synchronous belt 90, a longitudinal driven wheel assembly 91, a longitudinal driving plate 92, a longitudinal linear guide rail 93, a longitudinal slider mounting plate 94, a longitudinal loading linear rail 95 and a longitudinal belt pressing plate 96. The longitudinal in-place detection device comprises a longitudinal zero position optical coupler 97, a longitudinal zero position baffle 98, a longitudinal in-place detection baffle 99 and a longitudinal in-place detection optical coupler 100, and the longitudinal in-place buffer device comprises a longitudinal limiting pin 101 and a longitudinal loading spring 102.
In this embodiment, the longitudinal motor assembly 88, the longitudinal driven wheel assembly 91, the longitudinal linear guide 93 and the longitudinal zero position optocoupler 97 are all connected to the longitudinal bottom plate 89, the longitudinal linear guide 93 has a slider, the slider can move linearly along the length direction of the longitudinal linear guide 93, the longitudinal slider mounting plate 94 is connected to the slider of the longitudinal linear guide 93, the longitudinal loading linear guide 46 is mounted on the longitudinal slider mounting plate 94 by a screw, the longitudinal zero position blocking piece 98 and the longitudinal in-place detection blocking piece 99 are both fixed on the longitudinal slider mounting plate 94, the longitudinal loading linear guide 46 has a slider, and can move linearly along the length direction of the longitudinal loading linear guide 46, and the longitudinal driving plate 92 is mounted on the slider of the longitudinal loading linear guide 46 and can move along with the slider. The two ends of the longitudinal synchronous belt 90 are respectively sleeved on the longitudinal motor assembly 88 and the longitudinal driven wheel assembly 91, the longitudinal driving plate 92 is connected with the longitudinal synchronous belt 90 through the longitudinal belt pressing plate 96, and the longitudinal motor assembly 88 drives the longitudinal synchronous belt 90 to move so as to carry the longitudinal driving plate 92 to synchronously and linearly move together.
The two longitudinal loading springs 102 are arranged, one end of each longitudinal loading spring 102 is hung on the corresponding longitudinal limiting pin 101, the other end of each longitudinal loading spring 102 is hung on the lower end of the corresponding longitudinal driving plate 92, the upper ends of the longitudinal loading springs 102, which are pulled by the longitudinal loading linear guide rail 46, are attached to the corresponding longitudinal limiting pins 101, and the longitudinal in-place detection optocouplers 100 are fixed on the corresponding longitudinal driving plates 92 and move along with the corresponding longitudinal driving plates 92. Because the longitudinal zero position optocoupler 97 determines the zero position of the longitudinal driving plate 92, when the clamping mechanism 3 clamps the reagent box 78 to the outer ring turntable 6 or the inner ring turntable 7 for placement, and the length of the longitudinal driving plate 92 going downwards from the zero position is L distance, theoretically, the bottom of the reagent box 78 is contacted with the bottom of the first reagent position 15 or the bottom of the second reagent position 16, but due to the height error of the reagent box 78, the downward movement distance > L of the longitudinal driving plate 92 can cause the step-out of the longitudinal motor assembly 88 when the reagent box 78 is placed, and the downward movement distance < L of the longitudinal driving plate 92 can not place the reagent box 78 to introduce other faults; in addition, the first reagent site 15 and the second reagent site 16 are precisely positioned in the width direction of the reagent kit 78, and when the reagent kit 78 is inserted into the first reagent site 15 or the second reagent site 16, the first reagent site 15 or the second reagent site 16 is required to be aligned, but in practice, the alignment error of the reagent kit 78 and the first reagent site 15 or the second reagent site 16 is larger than the fit clearance of the reagent kit 78 and the first reagent site 15 and the second reagent site 16, so that rigid collision occurs with the side edges of the first reagent site 15 and the second reagent site 16 when the reagent kit 78 is inserted, and the longitudinal motor assembly 88 is out of step.
Therefore, in this embodiment, the longitudinal in-place buffer device and the longitudinal in-place detection device are provided, when the longitudinal driving plate 92 moves downwards by the length L distance during the process of inserting the reagent kit 78 into the first reagent place 15 and the second reagent place 16, the reagent kit 78 is theoretically reached to the bottom of the first reagent place 15 or the bottom of the second reagent place 16 at this time, but in order to ensure that the effective contact bottom is continued to move downwards by the distance g, when the longitudinal motor assembly 88 continues to drive the longitudinal synchronous belt 90 to move downwards with the longitudinal driving plate 92, the longitudinal driving plate 92 gradually breaks away from the longitudinal limiting pin 101 until the longitudinal driving plate 92 breaks away from the longitudinal in-place detection optocoupler 100, which is the default that the reagent kit 78 is in place when triggered.
The handling mechanism 2 further comprises a transverse in-place buffer device and a transverse in-place detection device, wherein the transverse handling device 53 comprises a transverse motor assembly 103, a transverse bottom plate 104, a transverse synchronous belt 105, a transverse driven wheel assembly 106, a transverse driving plate 107, a transverse linear guide rail 108, a transverse slider mounting plate 109 and a transverse loading linear rail 110. The transverse in-place detection device comprises a transverse zero position optical coupler 111, a transverse zero position blocking piece 112 and a transverse in-place detection optical coupler 113, and the transverse in-place buffer device comprises a transverse limiting pin 114 and a transverse loading spring 115.
The transverse motor assembly 103, the transverse driven wheel assembly 106, the transverse linear guide rail 108 and the transverse zero-position optocoupler 111 are connected to the transverse bottom plate 104, the transverse linear guide rail 108 is provided with a sliding block, the sliding block can linearly move along the length direction of the transverse linear guide rail 108, the transverse sliding block mounting plate 109 is connected with the sliding block of the transverse linear guide rail 108, the transverse loading linear guide rail 46 is mounted on the transverse sliding block mounting plate 109 through a screw, the transverse loading linear guide rail 46 is provided with the sliding block, and the transverse loading linear guide rail 46 can linearly move along the length direction of the transverse loading linear guide rail 46, and the transverse driving plate 107 is mounted on the sliding block of the transverse loading linear guide rail 46 and can move along with the sliding block. The two ends of the transverse synchronous belt 105 are respectively sleeved on the transverse motor assembly 103 and the transverse wheel assembly, the transverse driving plate 107 is connected with the X synchronous belt through the transverse belt pressing plate 84, and the transverse motor assembly 103 drives the transverse synchronous belt 105 to move so as to drive the transverse driving plate 107 to synchronously linearly move together.
Similar to the longitudinal handling device 54, two transverse loading springs 115 are provided, one ends of the transverse loading springs 115 are hung on the transverse limiting pins 114, the other ends of the transverse loading springs 115 are hung on one ends of the transverse driving plates 107, which are far away from the transverse limiting pins 114, the transverse loading springs 115 pull one ends of the transverse driving plates 107, which are close to the transverse limiting pins 114, along the transverse loading linear guide rail 46 to be attached to the transverse limiting pins 114, and the transverse in-place detection optocouplers 113 are fixed on the transverse driving plates 107 and move along with the transverse driving plates 107. When the clamping mechanism 3 clamps the reagent kit 78 on the outer ring turntable 6, as the distance of the clamp 58 of the reagent bottle bracket 79 of the reagent kit 78 extending into the outer ring turntable 6 is e, the reagent kit 78 cannot be taken out when the clamping mechanism 3 is vertically and upwards taken out, so that the transverse handling device 53 is required to reversely move along the clamp 58 by a distance d and d > e, meanwhile, the compressed distance of the elastic sheet 57 of the reagent kit 78 is d and d=the uncompressed distance f of the elastic sheet 57-the compressed distance f', thus the reagent kit 78 can be effectively separated from the edge of the outer ring turntable 6 and then the reagent kit 78 is taken out upwards, in order to avoid the step out of the transverse motor assembly 103 caused by rigid impact when the reagent kit 78 is transversely moved, and the moving distance of the reagent kit 78 is larger than d and the separation of the clamp 58 of the reagent kit 78 from the outer ring turntable 6 can be effectively detected, the transverse driving plate 107 is connected with a transverse in-place detection optocoupler 113, the transverse motor assembly 103 drives the transverse synchronous belt 105 to drive the transverse driving plate 107 to move, the transverse driving plate 107 transmits the tensile force to the transverse limiting pin 114 through pulling the transverse loading spring 115, the transverse limiting pin 114 is fixed on the transverse sliding block mounting plate 109, and the transverse carrying mechanism 2 is fixed on the transverse sliding block mounting plate 109 through screw connection, so that finally the transverse driving plate 107 transmits the power of the transverse motor assembly 103 to the clamping mechanism 3 through the spring to move the reagent box 78 for a distance d, after the distance d moves in place, the transverse loading spring 115 continues to overcome the resistance of the elastic sheet 57 of the reagent box 78 to generate stretching deformation until the transverse zero position blocking piece 112 (transverse in-place detection blocking piece) is separated from the transverse in-place detection optocoupler 113 (non-triggering state), at the moment, the transverse zero position blocking piece 112 triggers a distance K > d, the holding mechanism 3 can reliably take out the reagent cartridge 78.
In an alternative technical solution of this embodiment, the reagent disk mechanism 1 further includes a mixing device disposed in the reagent pot 8, where the mixing device is used for mixing the reagent kit 78.
In this embodiment, the mixing device includes a plurality of sector mixing gears 116, preferably four, and is uniformly fixed on the inner bottom surface of the reagent pot 8 by screws through the mixing gear support columns 83, and when the reagent box 78 of the outer ring turntable 6 rotates around the axis of the reagent disc mechanism 1, the reagent box also rotates around the axis of the sector mixing gears 116, and since the magnetic bead bottle 82 is connected with the sector mixing gears 116 by a gear pair, the magnetic bead bottle 82 can self-transfer to achieve the effect of mixing the magnetic bead reagent as the reagent box 78 rotates.
In an alternative technical solution of this embodiment, the reagent disk mechanism 1 further includes a retainer ring 55 disposed on an inner sidewall 59 of the reagent pot 8 and configured to cooperate with the reagent kit 78, and a notch 56 is disposed on the retainer ring 55, where the notch 56 corresponds to the automatic replacement port 11.
In this embodiment, the retainer ring 55 is mounted on the inner side wall 59 of the reagent pot 8 and is disposed directly above the spring plate 57 of the reagent bottle bracket 79, so as to prevent the reagent kit 78 from jumping up during mixing. The retainer ring 55 is provided with a notch 56, so that the retainer ring 55 is in a C-shaped structure, the notch 56 corresponds to the automatic replacement port 11, and an entrance is provided for automatic assembly and disassembly of the reagent kit 78 on the outer ring turntable 6.
In the alternative technical scheme of this embodiment, first reagent position 15 and second reagent position 16 are the slot, and the slot has relative first lateral wall and second lateral wall, and first lateral wall is used for the shell fragment 57 cooperation butt with reagent bottle support 79, and the second lateral wall is used for the buckle 58 cooperation joint with reagent bottle support 79, and specific, the second lateral wall is provided with dodges the mouth for dodging fan-shaped mixing gear 116, and buckle 58 joint is dodging the upper wall of mouth, namely outer lane carousel 6 corresponds the lower terminal surface 34 of dodging mouthful department promptly. The elastic piece 57 of the reagent bottle support 79 generates elastic force pushing the reagent kit 78 to approach the center of the outer ring turntable 6 through deformation, so that the reagent bottle support 79 is ensured to be tangent to the outer ring turntable 6, the center distance between the magnetic bead bottle 82 and the fan-shaped mixing gear 116 is ensured, and the purpose of mixing is achieved by ensuring effective engagement of the magnetic bead bottle support 79 and the fan-shaped mixing gear 116.
In this embodiment, preferably, the outer ring turntable 6 is provided with 40 first reagent positions 15 and is uniformly distributed in the circumferential direction, and the corresponding reagent boxes 78 are conveyed to the reagent suction port 12 or the automatic replacement port 11 under the drive of the outer ring driving device, required reagents are provided for a sample to be tested to the reagent suction port 12, and the clamping mechanism 3 takes away or puts the sucked reagent boxes 78 into a new reagent box 78 when reaching the prescription of the automatic replacement port 11; the function of inner circle carousel 7 is for storing new kit 78 and temporary storage outer lane carousel 6 on the kit 78 that finishes consuming, inner circle carousel 7 is provided with 10+1 second reagent position 16 and is circumference equipartition, can place 10 and wait to go up machine kit 78, and unnecessary second reagent position 16 is kit 78 temporary storage position, and under inner circle drive arrangement's drive, the empty second reagent position 16 of conveying and the corresponding kit 78 of waiting to go up machine are to automatic change mouth 11 department, make things convenient for fixture 3 to take away new kit 78 or put into empty kit 78.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present utility model, and not for limiting the same; although the utility model has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the utility model.

Claims (16)

1. An on-line loading and replacing system for a kit, comprising: the reagent disk mechanism (1), the reagent disk mechanism (1) comprises a reagent disk cover (5), an outer ring turntable (6), an inner ring turntable (7) and a reagent pot (8) for storing a reagent box (78) at a low temperature, the reagent disk cover (5) is covered on the reagent pot (8), and the outer ring turntable (6) and the inner ring turntable (7) are both arranged in the reagent pot (8) and can rotate relatively along the same axis;
the reagent disk cover (5) is provided with an outer ring loading port (9), an inner ring loading port (10), an automatic replacement port (11) and a reagent suction port (12), the outer ring loading port (9) and the reagent suction port (12) are corresponding to the outer ring turntable (6), the inner ring loading port (10) is corresponding to the inner ring turntable (7), the automatic replacement port (11) is corresponding to the inner ring turntable (7) and the outer ring turntable (6), the outer ring loading port (9) is provided with an outer ring cover (13), the inner ring loading port (10) is provided with an inner ring cover (14), and the automatic replacement port (11) is provided with a window cover (41);
The outer ring turntable (6) is provided with a plurality of first reagent positions (15) for loading the reagent boxes (78) along the circumferential direction, and the inner ring turntable (7) is provided with a plurality of second reagent positions (16) for loading the reagent boxes (78) along the circumferential direction.
2. The online kit loading and replacing system according to claim 1, wherein the reagent disk mechanism (1) further comprises a bottom plate (17), an inner ring driving device and an outer ring driving device;
the reagent pot (8) is provided with a bottom wall (18), the bottom wall (18) is fixedly connected with the bottom plate (17), and a space is arranged between the bottom wall (18) and the bottom plate (17);
the inner ring driving device and the outer ring driving device are both arranged on the bottom plate (17) and are both positioned at the interval, the bottom wall (18) is provided with a through hole, the inner ring driving device penetrates through the through hole to drive the inner ring turntable (7) to rotate, and the outer ring driving device penetrates through the through hole to drive the outer ring turntable (6) to rotate.
3. The online kit loading and replacing system according to claim 2, wherein the inner ring driving device comprises a main shaft (19), an inner ring shaft sleeve (20), an inner ring bearing (21), an inner ring connecting flange (22), an inner ring motor (23), an inner ring synchronous pulley (24) and an inner ring driving belt (25);
One end of the main shaft (19) is fixedly connected to the bottom plate (17), the other end of the main shaft is penetrated through the through hole, the inner ring shaft sleeve (20) is rotationally connected to the main shaft (19) through the inner ring bearing (21), and the inner ring turntable (7) is connected to the inner ring shaft sleeve (20) through the inner ring connecting flange (22);
the inner ring motor (23) is fixedly connected to the bottom plate (17), the inner ring synchronous belt wheel (24) is fixedly connected to the inner ring shaft sleeve (20), and the output end of the inner ring motor (23) is in transmission connection with the inner ring synchronous belt wheel (24) through the inner ring transmission belt (25).
4. The online kit loading and replacing system according to claim 3, wherein the outer ring driving device comprises an outer ring shaft sleeve (26), an outer ring bearing (27), an outer ring connecting flange (28), an outer ring motor (29), an outer ring synchronous pulley (30), an outer ring transmission belt (31) and an outer ring reduction gear (32);
the outer ring shaft sleeve (26) is rotationally connected to the inner ring shaft sleeve (20) through the outer ring bearing (27), and the outer ring turntable (6) is connected to the outer ring shaft sleeve (26) through the outer ring connecting flange (28);
the outer ring motor (29) is fixedly connected to the bottom plate (17), the outer ring synchronous pulley (30) is fixedly connected to the outer ring shaft sleeve (26), the output end of the outer ring motor (29) is in transmission connection with the outer ring reduction gear (32), and the outer ring reduction gear (32) is in transmission connection with the outer ring synchronous pulley (30) through the outer ring transmission belt (31).
5. The online reagent kit loading and replacing system according to claim 4, wherein the reagent disk mechanism (1) further comprises an inner ring code disk (33), an inner ring zero position optocoupler, an inner ring code tooth optocoupler, an outer ring code disk (36), an outer ring zero position optocoupler (37) and an outer ring code tooth optocoupler (38);
the inner ring connecting flange (22) is connected to the upper end of the inner ring shaft sleeve (20), the inner ring code disc (33) is connected to the lower end of the inner ring shaft sleeve (20), and the inner ring zero position optical coupler and the inner ring code tooth optical coupler are both connected to the bottom plate (17) and matched with the inner ring code disc (33);
the outer ring connecting flange (28) is connected to the upper end of the outer ring shaft sleeve (26), the outer ring code disc (36) is connected to the lower end of the outer ring shaft sleeve (26), and the outer ring zero position optocoupler (37) and the outer ring code tooth optocoupler (38) are both connected to the bottom plate (17) and matched with the outer ring code disc (36).
6. The online kit loading and replacing system according to claim 1, further comprising an outer ring RFID reader (39) and an inner ring RFID reader (40), wherein the outer ring RFID reader (39) is disposed in the reagent pot (8) and is used for reading RFID information of the kit (78) on the first reagent site (15), and the inner ring RFID reader (40) is disposed outside the reagent disk mechanism (1) and is used for reading RFID information of the kit (78) on the second reagent site (16).
7. The online kit loading and replacing system according to claim 1, further comprising an automatic opening and closing window mechanism (4), wherein the automatic opening and closing window mechanism (4) is used for driving the window cover (41) to automatically close or open the automatic replacing port (11).
8. The online loading and replacing system of the reagent kit according to claim 7, wherein the automatic opening and closing window mechanism (4) comprises an auxiliary guide rail (42), a first motor (43), a crank (44), a connecting rod (45), a linear guide rail (46), a limiting baffle (47) and a limiting optocoupler (48);
auxiliary guide rail (42) with linear guide rail (46) set up relatively and all fix on reagent dish lid (5), first motor (43) be fixed in reagent dish lid (5), and with crank (44) are connected, one end of connecting rod (45) with window lid (41) is articulated, the other end with crank (44) is articulated, spacing separation blade (47) set up in on crank (44), spacing opto-coupler (48) set up in on reagent dish lid (5) and with spacing separation blade (47) cooperation.
9. The on-line reagent cassette loading and changing system according to claim 1, further comprising a handling mechanism (2) and a clamping mechanism (3), the clamping mechanism (3) being adapted to clamp the reagent cassette (78), the handling mechanism (2) being adapted to drive the clamping mechanism (3) to move between the first reagent station (15) and the second reagent station (16).
10. The online loading and replacing system of the reagent kit according to claim 9, wherein the clamping mechanism (3) comprises a driving device, a front clamping jaw (49), a rear clamping jaw (50), a cam (51), a roller wheel and a return spring (52);
front clamping jaw (49) with back clamping jaw (50) set up relatively, just front clamping jaw (49) with all be provided with on back clamping jaw (50) the running roller, cam (51) set up two between the running roller, drive arrangement is used for the drive cam (51) rotate, cam (51) drive through rotating two front clamping jaw (49) with back clamping jaw (50) keep away from each other, return spring (52) one end connect in front clamping jaw (49), the other end connect in back clamping jaw (50), just return spring (52) are used for driving front clamping jaw (49) with back clamping jaw (50) are close to each other.
11. The online kit loading and replacing system according to claim 10, wherein a first positioning part is arranged on the kit (78), and a second positioning part matched with the first positioning part for positioning is arranged on each of the front clamping jaw (49) and the rear clamping jaw (50).
12. The online loading and changing system of reagent kits according to claim 9, wherein the handling mechanism (2) comprises a transverse handling device (53) and a longitudinal handling device (54);
The longitudinal handling device (54) is connected to the transverse handling device (53), and the clamping mechanism (3) is connected to the longitudinal handling device (54).
13. The online loading and replacing system of the reagent kit according to claim 12, wherein the carrying mechanism (2) further comprises a transverse in-place buffer device and a transverse in-place detection device which are arranged on the transverse carrying device (53), and a longitudinal in-place buffer device and a longitudinal in-place detection device which are arranged on the longitudinal carrying device (54).
14. The on-line reagent cartridge loading and replacing system according to claim 1, wherein the reagent tray mechanism (1) further comprises a mixing device arranged in the reagent pot (8) for mixing the reagent cartridge (78).
15. The online kit loading and replacing system according to claim 1, wherein the reagent disk mechanism (1) further comprises a retainer ring (55) arranged on an inner side wall (59) of the reagent pot (8) and used for being matched with the reagent kit (78), a notch (56) is arranged on the retainer ring (55), and the notch (56) corresponds to the automatic replacing port (11).
16. The online kit loading and replacing system according to claim 1, wherein one side of the kit (78) is provided with a spring plate (57), the other side is provided with a buckle (58), and the first reagent position (15) and the second reagent position (16) are respectively
A slot, wherein the slot is provided with a first side wall and a second side wall which are opposite, the first side wall is used for being matched and abutted with the elastic sheet (57),
the second side wall is used for being matched and clamped with the buckle (58).
CN202320057847.8U 2023-01-05 2023-01-05 Online loading and replacing system for reagent kit Active CN219320318U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202320057847.8U CN219320318U (en) 2023-01-05 2023-01-05 Online loading and replacing system for reagent kit

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202320057847.8U CN219320318U (en) 2023-01-05 2023-01-05 Online loading and replacing system for reagent kit

Publications (1)

Publication Number Publication Date
CN219320318U true CN219320318U (en) 2023-07-07

Family

ID=87024254

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202320057847.8U Active CN219320318U (en) 2023-01-05 2023-01-05 Online loading and replacing system for reagent kit

Country Status (1)

Country Link
CN (1) CN219320318U (en)

Similar Documents

Publication Publication Date Title
JP5323089B2 (en) Automatic loading of sample tubes for clinical analyzers
US8007722B2 (en) Analyzer
JP2019120699A (en) Chemiluminescence detector and its detection method
CN107407689B (en) Automatic analyzer
WO2009002358A1 (en) Mobile sample storage and retrieval unit for a laboratory automated sample handling worksystem
CN108802413A (en) Quantitative in vitro detecting instrument
CN208795750U (en) Quantitative in vitro detecting instrument
CN219266306U (en) Immune layer analyzer
CN109580596B (en) Chemiluminescent detector, incubation device and incubation method thereof
CN219320318U (en) Online loading and replacing system for reagent kit
EP0632271A1 (en) Improved transfer mechanism for automatic loading and unloading of reagent modules
CN213293935U (en) Outpatient service body fluid sample receiving equipment
CN109603950B (en) Reagent bottle clamping assembly, automatic loading mechanism and loading method thereof
CN112229988A (en) Outpatient clinic body fluid sample receiving equipment and control method
CN218674742U (en) Chemiluminescence apparatus
CN209471138U (en) A kind of reagent card automatic conveying device and full-automatic immunofluorescence analysis instrument
CN211955519U (en) Full-automatic blood coagulation tester
CN115184627A (en) Sample rack transfer device, transfer method, storage medium and sample analyzer
CN115877024A (en) System and method for online loading and automatic replacement of reagent kit
CN213474693U (en) Automatic reaction tube taking and placing device
CN111323609A (en) Full-automatic blood coagulation tester
CN218240065U (en) Automatic conveying and detecting device for rapid detection reagent card
CN216728344U (en) Double-scanning pre-detection device
CN221017461U (en) Automatic sorting device for blood samples
CN219799464U (en) Sample storage scheduling mechanism and full-automatic chemiluminescence immunoassay analyzer

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant