CN217385319U - Sample analyzer and electrolyte measuring mechanism - Google Patents

Abstract

The application discloses sample analysis appearance and electrolyte measurement mechanism, a sample analysis appearance, including electrolyte measurement mechanism, electrolyte measurement mechanism includes: a mounting seat; the plurality of conductive pieces are arranged on the mounting seat at intervals along a first direction; the detection electrodes are arranged on the mounting seat; the reference electrode is arranged on one side of the corresponding conductive piece along the second direction, the reference electrode and the plurality of detection electrodes are arranged along the first direction, and the reference electrode and each detection electrode are respectively and electrically connected with the corresponding conductive piece; the reference electrode is provided with a first containing cavity used for containing a first internal reference solution, and the orthographic projections of the first containing cavity and the at least two conductive pieces in the second direction at least partially coincide. In the application, the first accommodating cavity of the reference electrode has a larger volume and can accommodate more first internal reference solution, so that the service life of the reference electrode is prolonged.

Description

Sample analyzer and electrolyte measuring mechanism

Technical Field

The application belongs to the field of medical equipment, and particularly relates to a sample analyzer and an electrolyte measuring mechanism.

Background

The electrolyte analyzer is a medical instrument which is important in clinical examination and is mainly used for detecting the ion concentration in human blood.

In the related art, an electrode assembly of an electrolyte analyzer generally includes a detection electrode and a reference electrode which are used in cooperation. However, the reference electrode has a short service life, and the electrolyte analyzer needs to be replaced with a new reference electrode after a certain period of use.

SUMMERY OF THE UTILITY MODEL

The embodiment of the application provides a sample analyzer and an electrolyte measuring mechanism, which can prolong the service life of a reference electrode.

In a first aspect, embodiments of the present application provide a sample analyzer, including at least two measuring mechanisms for different measurement items, where the at least two measuring mechanisms for different detection items include an electrolyte measuring mechanism for measuring an ion concentration of a sample to be detected, and the electrolyte measuring mechanism includes:

a mounting base;

the plurality of conductive pieces are arranged on the mounting seat at intervals along a first direction;

the detection electrodes are arranged on the mounting seat and can be contacted with a sample to be detected to form a membrane potential;

the reference electrode is arranged on the mounting seat, the reference electrode is arranged on one side of the corresponding conductive piece along a second direction, the second direction is different from the first direction, the reference electrode and the plurality of detection electrodes are arranged along the first direction so that the sample to be detected sequentially flows through the detection electrodes and the reference electrode, and the reference electrode and each detection electrode are respectively and electrically connected with the corresponding conductive piece; and

the electrolyte measuring component is connected with the conductive piece and obtains the ion concentration of the sample to be detected through the electric signal transmitted by the conductive piece;

the reference electrode is provided with a first accommodating cavity, the first accommodating cavity is used for accommodating a first internal reference solution to form a reference potential, and the orthographic projections of the first accommodating cavity and the at least two conductive pieces in the second direction are at least partially overlapped.

Optionally, at least part of orthographic projections of the two to four conductive pieces and the first accommodating cavity in the second direction coincide.

Optionally, the first internal reference solution accommodated in the first accommodating cavity is an unsaturated potassium chloride solution.

Optionally, the reference electrode comprises:

the first shell is detachably mounted with the mounting seat and provided with a first accommodating cavity and a first flow passage communicated with the first accommodating cavity, and the first flow passage is used for accommodating a sample to be detected;

the ion exchange membrane is arranged on the first shell and used for partitioning the first accommodating cavity and the first flow channel;

the first electrode core is arranged in the first shell, one end of the first electrode core is positioned in the first accommodating cavity, and the other end of the first electrode core is abutted against the corresponding conductive piece; and

the first internal reference solution is contained in the first containing cavity, and the ion exchange membrane and at least part of the first electrode core are immersed in the first internal reference solution, so that the reference potential is formed on the interface of the first internal reference solution and the first electrode core.

Optionally, the detection electrode includes:

the second shell is detachably mounted with the mounting seat and is provided with a second accommodating cavity and a second flow passage communicated with the second accommodating cavity, and the second flow passage is used for accommodating a sample to be detected;

the ion sensitive film is connected with the second shell and used for partitioning the second accommodating cavity and the second flow channel;

the second electrode core is connected with the second shell, one end of the second electrode core is positioned in the second accommodating cavity, and the other end of the second electrode core is abutted to the corresponding conductive piece; and

the second internal reference solution is contained in the second containing cavity and immerses the ion sensitive membrane and at least part of the second electrode core, so that the second internal reference solution and a sample to be detected contained in the second flow channel can form the membrane potential at the ion sensitive membrane;

wherein, along the first direction, the second flow channels of all the detection electrodes and the first flow channels of the reference electrode are communicated in sequence.

Optionally, the plurality of detection electrodes include at least two of a potassium ion selective electrode, a sodium ion selective electrode, and a chloride ion selective electrode.

Optionally, the mounting base is provided with a mounting cavity, and the plurality of conductive members, the plurality of detection electrodes and the reference electrode are at least partially disposed in the mounting cavity.

Optionally, the sample analyzer further comprises:

the sample mechanism is used for bearing the sample to be detected;

the sample dispensing mechanism is used for transferring the sample to be detected;

the reagent mechanism is used for bearing a reagent; and

a reagent dispensing mechanism for transferring the reagent;

the at least two measuring mechanisms for different detection items further comprise a photometric mechanism, the photometric mechanism is used for performing photometric measurement on the incubated reaction liquid to obtain a detection result, and the reaction liquid is obtained by mixing the sample to be detected and the reagent.

The mounting seat is also provided with a sample container, the sample container is used for bearing a sample to be detected transferred by the sample separate injection mechanism, and the sample container is connected with the detection electrode and the reference electrode through a pipeline so that the sample to be detected can flow through the detection electrode and the reference electrode;

wherein, the mount pad with sample analyzer's support body demountable installation.

In a second aspect, an embodiment of the present application further provides an electrolyte measurement mechanism for measuring an ion concentration of a sample to be detected, where the electrolyte measurement mechanism includes:

a mounting seat;

the conductive pieces are arranged on the mounting seat at intervals along a first direction;

the detection electrodes are arranged on the mounting seat and can be contacted with a sample to be detected to form a membrane potential;

the reference electrode is arranged on the mounting seat, the reference electrode is arranged on one side of the corresponding conductive piece along a second direction, the second direction is different from the first direction, the reference electrode and the plurality of detection electrodes are arranged along the first direction so that the sample to be detected sequentially flows through the detection electrodes and the reference electrode, and the reference electrode and each detection electrode are respectively and electrically connected with the corresponding conductive piece; and

the electrolyte measuring component is connected with the conductive piece and obtains the ion concentration of the sample to be detected through the electric signal transmitted by the conductive piece;

the reference electrode is provided with a first accommodating cavity, the first accommodating cavity is used for accommodating a first internal reference solution to form a reference potential, and the orthographic projections of the first accommodating cavity and the at least two conductive pieces in the second direction are at least partially overlapped.

In a third aspect, an embodiment of the present application further provides an electrolyte measurement mechanism for measuring an ion concentration of a sample to be detected, where the electrolyte measurement mechanism includes:

a mounting seat;

the conductive pieces are arranged on the mounting seat at intervals along a first direction;

the detection electrodes are arranged on the mounting seat and provided with second accommodating cavities for accommodating a second internal reference solution to form a membrane potential;

the reference electrode is arranged on the mounting seat, the reference electrode and the plurality of detection electrodes are arranged along the first direction so that the sample to be detected sequentially flows through the detection electrodes and the reference electrode, and the reference electrode and each detection electrode are respectively and electrically connected with the corresponding conductive piece; and

the electrolyte measuring component is connected with the conductive piece and obtains the ion concentration of the sample to be detected through the electric signal transmitted by the conductive piece;

the reference electrode is provided with a first accommodating cavity, the first accommodating cavity is used for accommodating a first internal reference solution to form a reference potential, and the width of the first accommodating cavity in the first direction is two times or more than two times of the width of the second accommodating cavity in the first direction.

Optionally, the width of the first accommodating cavity in the first direction is four times or less than four times that of the second accommodating cavity in the first direction.

In the embodiment of the application, after the detection electrode and the reference electrode are in fluid connection with the same sample to be detected, the membrane potential formed at the detection electrode can be used for measuring the ion concentration in the sample to be detected in cooperation with the reference potential provided at the reference electrode. On the one hand, because the mounting seat is provided with the plurality of detection electrodes, the electrolyte measuring mechanism can detect the ion concentrations of different ions in the sample to be detected through the detection electrodes of different types, and the universality of the electrolyte measuring mechanism is further improved. On the other hand, in the conventional clinical test, the species of ions to be detected in the solution to be detected is less, so that the embodiment of the present application can be regarded as increasing the width of the reference electrode in the first direction, and the reference electrode occupies the installation space reserved for a few unusual detection electrodes in the installation seat after the size is increased. Therefore, the first accommodating cavity of the reference electrode can be made larger, so that the orthographic projection of the first accommodating cavity along the second direction is superposed with the orthographic projection of the at least two conductive pieces along the second direction, and finally, more first internal reference solution can be accommodated in the reference electrode so as to prolong the service life of the reference electrode.

Drawings

The technical solutions and advantages of the present application will become apparent from the following detailed description of specific embodiments of the present application when taken in conjunction with the accompanying drawings.

Fig. 1 is a schematic structural diagram of a sample analyzer according to an embodiment of the present disclosure.

FIG. 2 is a front view of an electrolyte measurement mechanism of the sample analyzer of FIG. 1.

Fig. 3 is an operational schematic diagram of the electrolyte measuring mechanism shown in fig. 2.

Fig. 4 is a side view of a reference electrode of the electrolyte measurement mechanism of fig. 2.

FIG. 5 is a cross-sectional view of the reference electrode shown in FIG. 4 taken along the direction A-A.

Fig. 6 is a side view of the detection electrode of the electrolyte measurement mechanism shown in fig. 2.

FIG. 7 is a cross-sectional view of the detection electrode shown in FIG. 6 taken along the direction B-B.

Fig. 8 is a partial enlarged view of the electrolyte measuring mechanism shown in fig. 2 at X.

Fig. 9 is a schematic view showing another structure of an electrolyte measuring mechanism in the sample analyzer shown in fig. 1.

The reference numbers in the figures are respectively:

100. an electrolyte measuring mechanism;

11. a mounting seat; 111. a mounting cavity;

12. a conductive member; 121. a third end face;

13. a reference electrode; 131. a first accommodating cavity; 132. a first housing; 133. an ion exchange membrane; 134. a first electrode core; 1341. a first end face; 135. a first flow passage; 136. a first mounting hole; 137. a first cover body; 138. a second mounting hole; 139. a first resilient seal member;

14. a detection electrode; 141. a second accommodating cavity; 142. a second housing; 143. an ion-sensitive membrane; 144. a second electrode core; 1441. a second end face; 145. a second flow passage; 146. a third mounting hole; 147. a second resilient seal member;

15. a sample container;

16. an electrolyte measurement component;

17. a reagent bin;

18. a first peristaltic pump;

19. a second peristaltic pump;

200. a light measurement mechanism;

300. a sample mechanism;

400. a sample dispensing mechanism;

500. a reagent mechanism;

600. a reagent dispensing mechanism;

700. a blending mechanism;

800. and (4) a reaction mechanism.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. It is to be understood that the embodiments described are only a few embodiments of the present application and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

Before describing the embodiments of the present application in detail, an example of the structure of a sample analyzer will be described.

Referring to fig. 1, fig. 1 is a schematic structural diagram of a sample analyzer according to an embodiment of the present disclosure. The sample analyzer may include a sample mechanism 300, a sample dispensing mechanism 400, a reagent mechanism 500, a reagent dispensing mechanism 600, and several measurement mechanisms for different measurement items. The sample mechanism 300 is used to carry a sample to be tested. The sample dispensing mechanism 400 is used to transfer a sample to be tested. The reagent mechanism 500 is used to carry reagents. The reagent dispensing mechanism 600 is used for transferring a reagent. The measuring mechanism is used for measuring a sample to be detected and/or a target object obtained by taking the sample to be detected as a raw material.

Illustratively, the measurement mechanism may include an electrolyte measurement mechanism 100 for measuring the ion concentration of the sample to be tested. The measuring mechanism may further comprise a photometric mechanism 200 for performing photometric measurement on the incubated reaction solution, wherein the reaction solution is obtained by mixing the sample to be detected provided by the sample dispensing mechanism 400 and the reagent provided by the reagent dispensing mechanism 600. Of course, depending on the requirements of the reagent measurement items, the sample analyzer may be provided with both the electrolyte measurement mechanism 100 and the photometric mechanism 200, or the sample analyzer may not be provided with either the electrolyte measurement mechanism 100 or the photometric mechanism 200, which is not limited in the embodiments of the present application.

The technical solution of the embodiment of the present application will be further explained and explained below with reference to the drawings and one of the structures of the electrolyte measuring mechanism 100.

Referring to fig. 2, fig. 2 is a front view of an electrolyte measuring mechanism of the sample analyzer shown in fig. 1. Electrolyte measurement mechanism 100 may include a mounting base 11, a number of conductive elements 12, a reference electrode 13, and a number of sensing electrodes 14.

The mounting seat 11 may serve as a mounting body of the electrolyte measuring mechanism 100 to mount and fix the conductive member 12, the detection electrode 14, the reference electrode 13, and the like, which are required during the measurement. Each detection electrode 14 is capable of contacting the sample to be detected to form a membrane potential. The reference electrode 13 is used to provide a reference potential. Reference electrode 13 and all detection electrodes 14 are electrically connected to respective corresponding conductive members 12, and based on this, conductive members 12 can be understood as electrical contacts for wiring reference electrode 13 and detection electrodes 14 mounted to mounting base 11.

Referring to fig. 3, fig. 3 is a schematic diagram of the electrolyte measuring mechanism shown in fig. 2. The ion concentration of the sample to be detected can be obtained from an electric signal transmitted from an electrolyte measuring part 16 through a conductive member 12, the conductive member 12 transmits the membrane potential of the detection electrode 14 and the reference potential of the reference electrode 13 to the electrolyte measuring part 16 in the form of electric signals, respectively, and the ion concentration of the sample to be detected is calculated in conjunction with the measurement. Illustratively, the conductive elements 12 of the detection electrode 14 and the reference electrode 13 are electrically connected to the electrolyte measuring part 16. At this time, the reference electrode 13 and the detection electrode 14 are both contacted with the same sample to be detected, so that a loop is formed among the electrolyte measuring part 16, the reference electrode 13, the sample to be detected and the detection electrode 14, and the electrolyte measuring part 16 can calculate the ion concentration of the sample to be detected through the membrane potential and reference potential combination meter.

It should be noted that the electrolyte measuring component 16 may be a component built in the electrolyte measuring mechanism 100, such as the electrolyte measuring component 16 is built in the mounting seat 11, and the electrolyte measuring component 16 may also be a component externally connected to the electrolyte measuring mechanism 100, which is not limited in the embodiment of the present application.

It can also be understood that, in the embodiment of the present application, since the plurality of detection electrodes 14 are disposed on the mounting seat 11, the electrolyte measuring mechanism 100 can measure the ion concentrations of different types of ions in the solution to be detected through different types of detection electrodes 14, thereby improving the versatility of the electrolyte measuring mechanism 100.

For example, the plurality of detection electrodes 14 may include at least two of a potassium ion selective electrode, a sodium ion selective electrode, and a chloride ion selective electrode. For example, the plurality of detection electrodes 14 may include a potassium ion selective electrode, a sodium ion selective electrode, and a chloride ion selective electrode, and the electrolyte measurement mechanism 100 may measure the potassium ion concentration in the sample to be detected by cooperating the potassium ion selective electrode with the reference electrode 13, or the electrolyte measurement mechanism 100 may measure the sodium ion concentration in the sample to be detected by cooperating the sodium ion selective electrode with the reference electrode 13, or the electrolyte measurement mechanism 100 may measure the chloride ion concentration in the sample to be detected by cooperating the chloride ion selective electrode with the reference electrode 13. Alternatively, the plurality of detection electrodes 14 may include only a potassium ion selective electrode and a sodium ion selective electrode, which is not limited in the embodiments of the present application.

With continued reference to fig. 4 and 5, fig. 4 is a side view of the reference electrode of the electrolyte measurement mechanism of fig. 2, and fig. 5 is a cross-sectional view of the reference electrode of fig. 4 taken along the direction a-a. It is understood that reference electrode 13 can be considered a consumable in electrolyte measurement mechanism 100. As shown in fig. 5, the reference electrode 13 has a first receiving cavity 131 therein, and the first receiving cavity 131 is used for receiving a first internal reference solution to form the reference potential. In general, the more the capacity of the first internal reference solution, the longer the service life of the reference electrode 13. Based on this, the service life of the reference electrode 13 can be prolonged by increasing the volume of the first accommodation chamber 131 so that more first internal reference solution can be accommodated inside the reference electrode 13.

Referring to fig. 2 and 5, in one embodiment of increasing the volume of the first accommodating cavity 131, a plurality of conductive members 12 are disposed at intervals on the mounting seat 11 along a first direction (a left-right direction shown in fig. 2). The reference electrode 13 is provided on one side of its corresponding conductive member 12 in the second direction (the vertical direction shown in fig. 2). The second direction is different from the first direction, and the reference electrode 13 and the plurality of detection electrodes 14 are arranged along the first direction, so that the sample to be detected sequentially flows through the detection electrodes 14 and the reference electrode 13, and the detection electrodes 14 and the reference electrode 13 are contacted with the same sample to be detected. The first accommodating cavity 131 is at least partially overlapped with orthographic projections of the at least two conductive members 12 in the second direction. For example, the first receiving cavity 131 may at least partially coincide with an orthographic projection of two, three, four or five conductive members 12 in the second direction, which is not limited in the embodiment of the present application.

In this embodiment of the present application, the first direction may be a vertical direction, the second direction may be a horizontal direction, the first direction may be a substantially vertical direction, the second direction may be an obliquely downward direction, the first direction may be a horizontal direction, and the second direction may be a vertical direction, which is not limited in this embodiment of the present application. In the following, several embodiments are exemplified by taking the first direction as a vertical direction and the second direction as a left-right direction of a horizontal direction, so as to explain and explain that the orthographic projections of the first accommodating cavity 131 and the at least two conductive members 12 in the second direction at least partially overlap:

of the two conductive members 12, one conductive member 12 completely coincides with the orthographic projection of the first accommodating cavity 131 in the vertical direction, and the other conductive member 12 partially coincides with the orthographic projection of the first accommodating cavity 131 in the vertical direction; or, the three conductive members 12 are completely overlapped with the orthographic projection area of the first accommodating cavity 131 in the vertical direction; or, three of the four conductive members 12 completely coincide with the orthographic projection area of the first accommodating cavity 131 in the vertical direction, and the remaining one conductive member 12 partially coincides with the orthographic projection area of the first accommodating cavity 131 in the vertical direction.

On the one hand, compared to only one conductive member 12 coinciding with the orthographic projection of the first receiving cavity 131 in the second direction (the vertical direction shown in fig. 2), the embodiment of the present application can be understood as that the width of the first receiving cavity 131 of the reference electrode 13 in the first direction (the left-right direction shown in fig. 2) is wider, so that the volume of the first receiving cavity 131 of the reference electrode 13 is larger to receive more first internal reference solution; eventually, the service life of reference electrode 13 can be increased to reduce the frequency of replacement of reference electrode 13.

On the other hand, referring to fig. 2, taking the installation base 11 provided with six conductive members 12 as an example, an installation space may also be preset on the installation base 11 to accommodate and install five detection electrodes 14 and a reference electrode with a smaller volume. However, in the conventional clinical test, the species of ions to be detected in the solution to be detected is less, so that the embodiment of the present application can increase the volume of the reference electrode with a smaller volume to form the reference electrode 13 with a larger volume in the embodiment of the present application, and the reference electrode 13 in the embodiment of the present application can be increased to occupy the position reserved for one reference electrode with a smaller volume in the installation space and the position reserved for at least one detection electrode 14 with a lower frequency in the installation space. Based on this, the volume of the first receiving cavity 131 of the reference electrode 13 can also be made larger, so as to achieve the purpose that the orthographic projections of the first receiving cavity 131 and the at least two conductive members 12 in the second direction at least partially overlap.

With continuing reference to fig. 6 and 7, fig. 6 is a side view of the sensing electrode of the electrolyte measuring mechanism of fig. 2, and fig. 7 is a cross-sectional view of the sensing electrode of fig. 6 taken along the direction B-B. In another embodiment of increasing the volume of the first accommodating chamber 131, a plurality of conductive members 12 are disposed at intervals along the first direction on the mounting seat 11. The reference electrode 13 and the plurality of detection electrodes 14 are arranged along the first direction, so that the sample to be detected sequentially flows through the detection electrodes 14 and the reference electrode 13, and the detection electrodes 14 and the reference electrode 13 are both contacted with the same sample to be detected. The detecting electrode 14 has a second accommodating chamber 141, and the second accommodating chamber 141 is used for accommodating a second internal reference solution to form the membrane potential. With reference to fig. 5 and 7, the width of the first receiving cavity 131 in the first direction (the left-right direction shown in fig. 2) is two times or more than two times the width of the second receiving cavity 141 in the first direction, so that the width of the first receiving cavity 131 of the reference electrode 13 in the first direction can be larger.

Of course, in order to avoid the reference electrode 13 from being too large in volume to occupy too much space and even unable to be mounted in the mounting seat 11, the width of the first receiving cavity 131 in the first direction is four times or less than four times the width of the second receiving cavity 141 in the first direction. For example, the width of the first receiving cavity 131 in the first direction is two times, six times, three times, five times or four times that of the second receiving cavity 141 in the first direction.

It can be further understood that, when the width of the first receiving cavity 131 in the first direction (the left-right direction shown in fig. 2) is two times or more than the width of the second receiving cavity 141 in the first direction, the first receiving cavity 131 may at least partially coincide with the orthographic projection of at least two conductive members 12 in the second direction, or as shown in fig. 2, three conductive members 12 located directly above the first receiving cavity 131 are mounted on the mounting base 11, and only the rightmost conductive member 12 of the three conductive members 12 abuts against the reference electrode 13 to form an electrical connection. Alternatively, when the width of the first receiving cavity 131 in the first direction is two times or more than two times the width of the second receiving cavity 141 in the first direction, the first receiving cavity 131 may at least partially coincide with the orthographic projection of one conductive member 12 in the second direction, or only one conductive member 12 located directly above the first receiving cavity 131 is mounted on the mounting base 11, and the conductive member 12 abuts against the reference electrode 13 to form an electrical connection.

The increase in the size of the reference electrode 13 in the embodiment of the present application will be further explained and explained below in conjunction with one of the sizes of the reference electrode 13 and the detection electrode 14.

As shown in fig. 2, the mounting base 11 has a mounting cavity 111, and the plurality of conductive members 12, the plurality of detection electrodes 14, and the reference electrode 13 are disposed at least partially in the mounting cavity 111. For example, six conductive members 12 are arranged in a left-right direction and provided at an upper portion in the mounting cavity 111. The three detection electrodes 14 and the one reference electrode 13 are arranged in the left-right direction and are provided at the lower portion in the mounting chamber 111. At this time, the widths of the three detection electrodes 14 in the left-right direction are all between 12 mm and 13 mm, the width of the reference electrode 13 in the left-right direction is between 45 mm and 46 mm, and the three detection electrodes 14 and the one reference electrode 13 can be locked in the mounting cavity 111 after being arranged in the left-right direction.

Referring to fig. 5, the width of the reference electrode 13 in the first direction (left-right direction shown in fig. 5) may be 46 mm, and the width of the first receiving cavity 131 in the first direction may be 45 mm. At this time, only one conductive member 12 may be located right above the first receiving chamber 131, and the reference electrode 13 is electrically connected to the conductive member 12. Alternatively, three conductive members 12 are positioned directly above first receiving cavity 131, and reference electrode 13 is electrically connected to only one of conductive members 12.

Next, referring to fig. 5, the technical solution of the embodiment of the present application is further explained and explained by taking one of the structures of the reference electrode 13 as an example.

The reference electrode 13 includes a first case 132, an ion exchange membrane 133, a first electrode core 134, and the above-described first internal reference solution (not shown in the figure).

The first housing 132 is detachably mounted on the mounting base 11, such as the first housing 132 is clamped to the mounting base 11, sleeved, screwed, magnetically attracted, and the like, which is not limited in this embodiment of the application. The first housing 132 has a first receiving chamber 131 and a first flow passage 135 communicating with the first receiving chamber 131, and the first flow passage 135 is used for receiving a sample to be tested. The ion exchange membrane 133 is disposed in the first casing 132, and the ion exchange membrane 133 partitions the first accommodating cavity 131 and the first flow passage 135. The first electrode core 134 is disposed in the first casing 132, one end of the first electrode core 134 is located in the first accommodating cavity 131, and the other end of the first electrode core 134 abuts against the corresponding conductive member 12 to form an electrical connection. At this time, the first internal reference solution is accommodated in the first accommodating chamber 131, and the ion exchange membrane 133 and at least a part of the first electrode core 134 are immersed by the first internal reference solution, so that the reference potential is formed at the interface between the first internal reference solution and the first electrode core 134.

It can be understood that, when the sample to be detected flows through the first flow channel 135 and contacts the ion exchange membrane 133, the first electrode core 134 of the reference electrode 13 is electrically connected to the sample to be detected sequentially through the first internal reference solution and the ion exchange membrane 133. At this time, if the detecting electrode 14 is also in contact with the sample to be detected to form a membrane potential, the electrolyte measuring unit 16, the reference electrode 13, the sample to be detected and the detecting electrode 14 form a loop, so that the electrolyte measuring unit 16 can detect the ion concentration of the sample to be detected by the reference potential and the membrane potential.

In some embodiments, the first housing 132 may further be provided with a first mounting hole 136 communicating with the first receiving cavity 131. The first mounting hole 136 faces the ion exchange membrane 133, and the ion exchange membrane 133 can pass through the first mounting hole 136. Furthermore, the operator can insert the ion exchange membrane 133 into the first receiving chamber 131 through the first mounting hole 136 to block the first receiving chamber 131 and the first flow passage 135, or can take out the ion exchange membrane 133 to be replaced through the first mounting hole 136. Of course, the first mounting hole 136 may also be used to inject the first internal reference solution into the first accommodating cavity 131, or pour out the first internal reference solution in the first accommodating cavity 131, which is not limited in this application.

Accordingly, the reference electrode 13 may further include a first cover 137, and the first cover 137 may be used to open or close the first mounting hole 136. For example, the first mounting hole 136 is a threaded hole, and the first cover 137 can be screwed into the first mounting hole 136, and the structure of the first cover 137 for closing or opening the first mounting hole 136 is not limited in the embodiments of the present application.

In some embodiments, the first housing 132 may further be provided with a second mounting hole 138 communicating with the first receiving chamber 131. The second mounting hole 138 is used to mount the first electrode core 134, and the first electrode core 134 is detachably disposed to the first case 132 through the second mounting hole 138. For example, the second mounting hole 138 may be a threaded hole, and the sidewall of the first electrode core 134 may have an external thread to be threadably engaged with the second mounting hole 138. Of course, when the first electrode core 134 is taken down from the first casing 132, the second installation hole 138 is opened, and the second installation hole 138 may be used to inject the first internal reference solution into the first accommodation cavity 131, or pour out the first internal reference solution in the first accommodation cavity 131, which is not limited in this embodiment of the application.

The first internal reference solution may be a potassium chloride solution. In the related art, the potassium chloride solution is a saturated solution, or the first internal reference solution is a saturated potassium chloride solution. Potassium ions in the saturated potassium chloride solution easily pass through the ion exchange membrane 133 and precipitate crystals, eventually resulting in the surface of the ion exchange membrane 133 on the side toward the first flow channel 135 being blocked by the precipitated crystals.

Based on this, in the embodiment of the present application, the first internal reference solution is an unsaturated potassium chloride solution. It will be appreciated that unsaturated potassium chloride solutions are less prone to crystallization during use than saturated potassium chloride solutions, and thus the risk of blockage of the ion exchange membrane 133 may be reduced to improve the reliability and life of the reference electrode 13.

Wherein the unsaturated potassium chloride solution may be a potassium chloride solution having a concentration of less than 15% w/v. For example, the unsaturated potassium chloride solution may be a 14% w/v potassium chloride solution, a 7.6% w/v potassium chloride solution, or a 1% w/v potassium chloride solution.

In the following, with reference to fig. 7, the technical solution of the embodiment of the present application is further explained and explained by taking one of the structures of the detection electrode 14 as an example.

The detection electrode 14 may include a second housing 142, an ion sensitive membrane 143, a second electrode core 144, and a second internal reference solution (not shown in the figure).

The second housing 142 and the mounting base 11 are detachably mounted, such as the second housing 142 and the mounting base 11 are clamped, sleeved, screwed, magnetically attracted, and the like, which is not limited in the embodiment of the present application. The second housing 142 has a second accommodating chamber 141 and a second flow channel 145 communicating with the second accommodating chamber 141, and the second flow channel 145 is used for accommodating a sample to be tested. The ion sensitive film 143 is connected to the second housing 142, and the second ion sensitive film 143 partitions the second accommodating chamber 141 and the second flow channel 145. The second electrode core 144 is connected to the second housing 142, one end of the second electrode core 144 is located in the second accommodating cavity 141, and the other end of the second electrode core 144 abuts against the corresponding conductive member 12 to form an electrical connection. The second internal reference solution is contained in the second containing cavity 141, and the second internal reference solution submerges the ion sensitive membrane 143 and at least a part of the second electrode core 144, so that the second internal reference solution and the sample to be detected contained in the second flow channel 145 can form the membrane potential at the ion sensitive membrane 143.

It can be understood that when the sample to be detected flows through the second flow channel 145 and contacts the ion-sensitive membrane 143, if the ion exchange membrane 133 of the reference electrode 13 also contacts the sample to be detected, the electrolyte measuring part 16, the reference electrode 13, the sample to be detected, and the detection electrode 14 form a loop, so that the electrolyte measuring part 16 can measure the ion concentration of the sample to be detected through the membrane potential and the reference potential.

Referring to fig. 9, fig. 9 is a schematic view of another structure of the electrolyte measuring mechanism in the sample analyzer shown in fig. 1. In some embodiments, the mounting seat 11 may further be provided with a sample container 15, and the sample container 15 is used for carrying a sample to be detected, so that the reference electrode 13 and the detection electrode 14 can perform ion concentration detection on the sample to be detected. The sample container 15 and the mounting seat 11 may be integrally formed, and may be detachably connected and fixed, which is not limited in this embodiment of the application. The mounting base 11 can be detachably mounted and fixed with the rack of the sample analyzer, such as the mounting base 11 is screwed or clamped on the working table of the rack of the sample analyzer. It can be understood that, since the sample container 15, the detection electrode 14, the reference electrode 13, the conductive member 12, and the like are disposed on the mounting base 11, the whole electrolyte measuring mechanism 100 can be quickly disassembled and assembled by disassembling and assembling the mounting base 11 and the whole sample analyzer frame, so that the whole electrolyte measuring mechanism 100 has the advantage of easy disassembly and assembly.

In some embodiments, the first flow channel 135 of the reference electrode 13 and the second flow channel 145 of the detection electrode 14 are both immersed in the sample to be detected in the sample container 15, so that the electrolyte measuring part 16 can perform the measurement of the ion concentration of the sample to be detected by the membrane potential and the reference potential.

Alternatively, as shown in fig. 9, the sample container 15 may be connected to the detection electrode 14 and the reference electrode 13 through a pipe so that the sample to be detected in the sample container 15 can flow through the detection electrode 14 and the reference electrode 13.

For example, with continued reference to fig. 2, 5 and 7, in the first direction (the left-right direction shown in fig. 2, 5 or 7), the second flow channels 145 of all the detection electrodes 14 and the first flow channels 135 of the reference electrode 13 are sequentially communicated, and then the detection of the ion concentration of the sample to be detected can be achieved by filling all the second flow channels 145 and the first flow channels 135 with a small amount of the sample to be detected in the sample container 15. As can be seen, the electrolyte measuring mechanism 100 of the present embodiment can reduce the cost and the workload of measurement because the amount of the sample to be measured is smaller.

In some embodiments, as shown in fig. 9, the electrolyte measurement mechanism 100 can further include a reagent reservoir 17 and a first peristaltic pump 18. Reagent chamber 17 is used to carry one or more calibration liquids used in the calibration operation of electrolyte measuring mechanism 100. The first peristaltic pump 18 is used to move the calibration solution in the reagent chamber 17 into the sample container 15. For example, the reagent chamber 17 has several sample bags (not shown in the figure), and different sample bags are used for carrying different calibration solutions. The plurality of first peristaltic pumps 18 correspond to the plurality of sample bags one by one, and each first peristaltic pump 18 pumps the calibration solution in the corresponding sample bag to the sample container 15, although other containers may be used in the reagent chamber 17 instead of the sample bag, which is not limited in this embodiment of the present invention.

In some other embodiments, the reagent chamber 17 may further have a waste liquid recovery bag (not shown) therein for carrying the sample or calibration liquid to be detected at the reference electrode 13 and the detection electrode 14. As shown in fig. 9, a second peristaltic pump 19 may be connected to the waste liquid recovery bag, and the sample or calibration liquid to be detected at the reference electrode 13 and the detection electrode 14 may be pumped into the waste liquid recovery bag by the second peristaltic pump 19.

Illustratively, continuing with fig. 2, 5, 7 and 9, the inlet end of the second peristaltic pump 19 may be connected to the outlet end of the first flow channel 135 of the reference electrode 13, and the outlet end of the second peristaltic pump 19 may be connected to a waste fluid recovery bag. The liquid inlet end of the second flow channel 145 of the leftmost detecting electrode 14 shown in fig. 2 is connected to the sample container 15 through a pipe, when the second peristaltic pump 19 operates, the second peristaltic pump 19 can make the first flow channel 135 and all the second flow channels 145 form a negative pressure, and the sample to be detected in the sample container 15 can be sucked into the first flow channel 135 and the second flow channels 145 through the negative pressure.

In some embodiments, as shown in fig. 7, at least one end of each second flow channel 145 may be provided with a second elastic sealing member 147, as shown in fig. 4, at least one end of the first flow channel 135 may be provided with a first elastic sealing member 139, so that two connected second flow channels 145 can be sealed by at least one second elastic sealing member 147, and the connected first flow channel 135 and second flow channel 145 can be sealed by one first elastic sealing member 139 and/or one second elastic sealing member 147.

In some embodiments, as shown in fig. 7, the second housing 142 may further be provided with a third mounting hole 146 communicating with the second accommodating chamber 141. The third mounting hole 146 is used to mount the second electrode core 144, and the second electrode core 144 is detachably disposed in the second case 142 through the third mounting hole 146.

Illustratively, the third mounting hole 146 may be a threaded hole, and the sidewall of the second electrode core 144 has an external thread to be threadably coupled to the third mounting hole 146. Of course, when the second electrode core 144 is taken down from the second casing 142, the third installation hole 146 is opened, and the third installation hole 146 may be used to inject the second internal reference solution into the second accommodation cavity 141, or pour out the second internal reference solution in the second accommodation cavity 141, which is not limited in this embodiment of the application.

Referring to fig. 8, fig. 8 is a partial enlarged view of the electrolyte measuring mechanism shown in fig. 2 at X. The conductive members 12 include third end surfaces 121 abutting against the corresponding detection electrodes 14 or reference electrodes 13 to form an electrical connection, and the third end surface 121 of each conductive member 12 may be a flat surface, a convex surface, or a concave surface, which is not limited in the embodiment of the present application.

As shown in fig. 2 or 8, the third end surface 121 of at least one of the conductive members 12 may be provided as a convex surface for the convenience of maintenance and inspection of the conductive members 12. It can be understood that the repeated assembly and disassembly of the reference electrode 13 and the detection electrode 14 can easily cause the third end surface 121 to be worn or stained. In the embodiment of the present application, the third end surface 121 is set to be a convex surface, so that an operator can directly observe whether the third end surface 121 is stained or worn, and the like, thereby forming a hidden danger of electrical connection between the conductive member 12 and the corresponding detection electrode 14 or reference electrode 13. It can be seen that the conductive member 12 of the embodiment of the present application improves the safety of the electrolyte measuring mechanism 100 and facilitates the maintenance and inspection of the electrolyte measuring mechanism 100.

The convex third end surface 121 may be spherical, or it may be understood that the third end surface 121 of at least one conductive member 12 is spherical. The third end surface 121 is set to be a spherical surface, so that a sharp corner of the third end surface 121 can be avoided, and then in the process of assembling and disassembling the reference electrode 13 or the detection electrode 14, the corresponding parts of the reference electrode 13, the detection electrode 14 and the conductive member 12 are scratched or abraded, and further, the safety and the service life of the electrolyte measuring mechanism 100 are improved.

Accordingly, as shown in fig. 5, reference electrode 13 may have a first end face 1341 that is in abutting electrical connection with third end face 121 of conductive member 12. In combination with one of the above-mentioned structures of the reference electrode 13, the end of the first electrode core 134 facing the conductive member 12 may be provided with a first end face 1341. The first end surface 1341 may be convex, flat, or concave for matching with the third end surface 121, which is not limited in this embodiment.

In the embodiment where the third end surface 121 is a spherical surface and the first end surface 1341 is also a spherical surface, ideally, the lower vertex of the third end surface 121 and the upper vertex of the first end surface 1341 are both accurately located at predetermined positions to form a point contact, so that the conductive member 12 and the reference electrode 13 are electrically connected. However, in actual operation, manufacturing tolerances, assembly tolerances, and the like of the conductive member 12 and the reference electrode 13 are inevitable, and the conductive member 12 and the reference electrode 13 are liable to be shaken and displaced when the electrolyte measuring mechanism 100 vibrates, which may cause horizontal misalignment between the upper vertex of the first end face 1341 and the lower vertex of the third end face 121, and thus disconnection of electrical contact between the first end face 1341 and the third end face 121. It can be seen that if third end surface 121 is spherical and first end surface 1341 is also spherical, the electrical connection formed between conductive member 12 and reference electrode 13 is not stable.

Thus, in a preferred embodiment, the first end 1341 can be planar or concave to mate with the third end 121. When the first end surface 1341 is a plane, even if the conductive member 12 and the first electrode core 134 have a certain position error, the lower vertex of the third end surface 121 can still abut against different positions of the first end surface 1341, thereby improving the stability of the electrical connection between the conductive member 12 and the first electrode core 134. If the first end surface 1341 is a concave surface, the first end surface 1341 may wrap the third end surface 121 to perform position correction on the conductive member 12 and the first electrode core 134, thereby improving the stability of the electrical connection between the conductive member 12 and the first electrode core 134.

Accordingly, as shown in fig. 7 or 8, the detecting electrode 14 may have a second end surface 1441 abutting against the third end surface 121 of the conductive member 12 to form an electrical connection. In combination with one structure of the detection electrode 14, the second electrode core 144 may have a second end surface 1441 facing the conductive member 12. The second end surface 1441 may be a convex surface, a flat surface, or a concave surface matched with the third end surface 121, which is not limited in the embodiment of the present application.

It can be understood that, in the scheme that the third end surface 121 is a spherical surface, and the second end surface 1441 is also a spherical surface, ideally, the lower vertex of the third end surface 121 and the upper vertex of the second end surface 1441 are both accurately located at the preset position to form a point contact, so that the detection electrode 14 and the conductive member 12 are electrically connected. However, in actual operation, manufacturing tolerances, assembly tolerances, etc. of conductive member 12 and detection electrode 14 are inevitable, and conductive member 12 and reference electrode 13 are liable to shake in the presence of vibration of electrolyte measuring mechanism 100, which may cause horizontal misalignment of the upper vertex of second end surface 1441 and the lower vertex of third end surface 121, and thus disconnection of electrical contact between first end surface 1341 and third end surface 121. It can be seen that the electrical connection between the conductive member 12 and the detection electrode 14 is not stable if the third end surface 121 is spherical and the second end surface 1441 is also spherical.

Thus, in a preferred embodiment, the second end surface 1441 may be a flat surface or a concave surface that mates with the third end surface 121. When the second end surface 1441 is a plane, even if there is a certain position error between the conductive member 12 and the second electrode core 144, the lower vertex of the third end surface 121 may abut against different positions of the second end surface 1441, thereby improving the stability of the electrical connection between the conductive member 12 and the first electrode core 134. If the second end surface 1441 is a concave surface, the second end surface 1441 may wrap the third end surface 121 to perform position correction on the conductive member 12 and the second electrode core 144, so as to improve the stability of the electrical connection between the conductive member 12 and the second electrode core 144.

In some embodiments, the third end surface 121 of at least one conductive member 12 may have a metal conductive layer (not labeled). The metal conductive layer may be formed of a metal material with better conductivity, such as gold or copper, plated on the conductive member 12, so as to improve the conductivity of the conductive member 12.

The photometric mechanism 200 is used to perform photometric measurement on the incubated reaction solution to obtain reaction data of the sample. For example, the photometric means 200 detects the light emission intensity of the reaction solution to be measured, and calculates the concentration of the component to be measured in the sample from the calibration curve.

The above is some examples of measurement mechanisms and the following continues with a description of other components and structures in the sample analyzer.

As shown in fig. 1, the Sample mechanism 300 may include a Sample Delivery Module (SDM) and a front end rail. In other embodiments, the sample mechanism 300 may also be a sample tray that includes a plurality of sample sites on which samples, such as sample tubes, may be placed, and the sample tray may be configured to dispense the samples to corresponding locations by rotating the tray, such as locations where the samples are to be aspirated by the sample dispensing mechanism 400.

As shown in fig. 1, the sample dispensing mechanism 400 is used for transferring the sample to be tested, which is carried by the sample mechanism 300, to the container to be loaded. For example, the sample dispensing mechanism 400 may include a sample needle that performs two-dimensional or three-dimensional movement in space by a two-dimensional or three-dimensional driving mechanism, so that the sample needle can move to suck the sample to be detected carried by the sample mechanism 300, and move to the container to be loaded, and discharge the sample to be detected to the container to be loaded.

Here, different measurement operations may be performed by using different sample vessels to be loaded in cooperation with different measurement mechanisms according to actual measurement project requirements. For example, the sample-adding container includes a reaction cup in which a sample to be tested and a reagent are mixed to obtain a reaction solution, and the photometric mechanism 200 can perform photometric operation on the reaction solution in the reaction cup, and the sample container 15. The sample to be tested may also be transferred to the sample container 15 for measurement of the ion concentration.

Here, the electrolyte measuring mechanism 100 may measure the ion concentration by a direct method or may measure the ion concentration by an indirect method. The difference between direct and indirect ion concentration measurement is whether the ion concentration measurement is started after the sample to be detected is diluted. In connection with the above-described sample container 15, it may be possible to dilute the sample to be detected at the sample container 15 to perform indirect measurement of the ion concentration. Alternatively, it is also possible that the sample to be tested at the sample container 15 is not diluted to accomplish direct measurement of the ion concentration.

As shown in fig. 1, the reagent mechanism 500 may be a reagent disk, which is configured in a disk-shaped structure and has a plurality of positions for carrying reagent containers, and the reagent mechanism 500 can rotate and drive the reagent containers carried by the reagent mechanism to rotate to a specific position, for example, a position for sucking reagent by the reagent dispensing mechanism 600. The number of reagent mechanisms 500 may be one or more.

As shown in fig. 1, a reagent dispensing mechanism 600 is used to aspirate and discharge a reagent into a reaction cup to which the reagent is to be added. In one embodiment, the reagent dispensing mechanism 600 may include a reagent needle that performs a two-dimensional or three-dimensional motion in space by a two-dimensional or three-dimensional driving mechanism, so that the reagent needle may move to aspirate a reagent carried by the reagent mechanism 500 and to a cuvette to which the reagent is to be added and discharge the reagent to the cuvette.

As shown in fig. 1, the sample analyzer may further include a reaction mechanism 800 and a homogenization mechanism 700.

As shown in FIG. 1, the reaction unit 800 has at least one placement position for placing the above reaction cuvette and incubating the reaction solution in the reaction cuvette. For example, the reaction mechanism 800 may be a reaction tray, which is arranged in a disc-shaped structure and has one or more placing positions for placing reaction cups, and the reaction tray can rotate and drive the reaction cups in the placing positions to rotate, so as to schedule the reaction cups in the reaction tray and incubate the reaction solution in the reaction cups.

The mixing mechanism is used for mixing the reaction liquid to be mixed uniformly in the reaction mechanism 800. The number of the blending mechanisms can be one or more.

The electrolyte measuring mechanism 100 and the sample analyzer provided in the embodiments of the present application are described in detail, and the principles and embodiments of the present application are explained herein by using specific examples, which are only used to help understand the method and the core concept of the present application; meanwhile, for those skilled in the art, according to the idea of the present application, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present application.

Claims (12)

1. A sample analyzer, comprising at least two measuring mechanisms for different measuring items, the at least two measuring mechanisms for different detecting items comprising an electrolyte measuring mechanism for measuring an ion concentration of a sample to be detected, the electrolyte measuring mechanism comprising:

a mounting seat;

the plurality of conductive pieces are arranged on the mounting seat at intervals along a first direction; the detection electrodes are arranged on the mounting seat and can be contacted with a sample to be detected to form a membrane potential;

the reference electrode is arranged on the mounting seat, the reference electrode is arranged on one side of the corresponding conductive piece along a second direction, the second direction is different from the first direction, the reference electrode and the plurality of detection electrodes are arranged along the first direction so that the sample to be detected sequentially flows through the detection electrodes and the reference electrode, and the reference electrode and each detection electrode are respectively and electrically connected with the corresponding conductive piece; and

the electrolyte measuring component is connected with the conductive piece and obtains the ion concentration of the sample to be detected through an electric signal transmitted by the conductive piece;

the reference electrode is provided with a first accommodating cavity, the first accommodating cavity is used for accommodating a first internal reference solution to form a reference potential, and the orthographic projections of the first accommodating cavity and the at least two conductive pieces in the second direction are at least partially overlapped.

2. The sample analyzer of claim 1, wherein two to four of the conductive members at least partially coincide with an orthographic projection of the first receiving cavity in the second direction.

3. The sample analyzer of claim 1, wherein the first internal reference solution contained in the first containing cavity is an unsaturated potassium chloride solution.

4. The sample analyzer of any of claims 1 to 3, wherein the reference electrode comprises:

the first shell is detachably mounted with the mounting seat and provided with a first accommodating cavity and a first flow passage communicated with the first accommodating cavity, and the first flow passage is used for accommodating a sample to be detected;

the ion exchange membrane is arranged on the first shell and used for separating the first accommodating cavity from the first flow channel;

the first electrode core is arranged in the first shell, one end of the first electrode core is positioned in the first accommodating cavity, and the other end of the first electrode core is abutted against the corresponding conductive piece; and

and the first inner reference solution is contained in the first containing cavity, and the ion exchange membrane and at least part of the first electrode core are immersed in the first inner reference solution, so that the reference potential is formed on the interface of the first inner reference solution and the first electrode core.

5. The sample analyzer of claim 4, wherein the detection electrode comprises:

the second shell is detachably mounted with the mounting seat and is provided with a second accommodating cavity and a second flow passage communicated with the second accommodating cavity, and the second flow passage is used for accommodating a sample to be detected;

the ion sensitive film is connected with the second shell and used for separating the second accommodating cavity from the second flow channel;

the second electrode core is connected with the second shell, one end of the second electrode core is positioned in the second accommodating cavity, and the other end of the second electrode core is abutted to the corresponding conductive piece; and

the second internal reference solution is contained in the second containing cavity and immerses the ion sensitive membrane and at least part of the second electrode core, so that the second internal reference solution and a sample to be detected contained in the second flow channel can form the membrane potential at the ion sensitive membrane;

wherein, along the first direction, the second flow channels of all the detection electrodes and the first flow channels of the reference electrode are communicated in sequence.

6. The sample analyzer of any of claims 1 to 3 wherein the plurality of detection electrodes includes at least two of a potassium ion selective electrode, a sodium ion selective electrode, and a chloride ion selective electrode.

7. The sample analyzer of any of claims 1-3, wherein the mounting base is provided with a mounting cavity, and the plurality of conductive elements, the plurality of detection electrodes, and the reference electrode are all at least partially disposed within the mounting cavity.

8. The sample analyzer of any of claims 1 to 3, further comprising:

the sample mechanism is used for bearing the sample to be detected;

the sample dispensing mechanism is used for transferring the sample to be detected;

the reagent mechanism is used for bearing a reagent; and

a reagent dispensing mechanism for transferring the reagent;

the at least two measuring mechanisms for different detection items further comprise a photometric mechanism, the photometric mechanism is used for performing photometric measurement on the incubated reaction liquid to obtain a detection result, and the reaction liquid is obtained by mixing the sample to be detected and the reagent.

9. The sample analyzer as claimed in claim 8, wherein the mounting base is further provided with a sample container for carrying the sample to be detected transferred by the sample dispensing mechanism, and the sample container is connected with the detection electrode and the reference electrode through a pipeline so that the sample to be detected can flow through the detection electrode and the reference electrode;

the mounting base and the frame body of the sample analyzer are detachably mounted.

10. An electrolyte measuring mechanism for measuring an ion concentration of a sample to be tested, the electrolyte measuring mechanism comprising:

a mounting seat;

the plurality of conductive pieces are arranged on the mounting seat at intervals along a first direction;

the detection electrodes are arranged on the mounting seat and can be contacted with a sample to be detected to form a membrane potential;

the reference electrode is arranged on the mounting seat, the reference electrode is arranged on one side of the corresponding conductive piece along a second direction, the second direction is different from the first direction, the reference electrode and the plurality of detection electrodes are arranged along the first direction so that the sample to be detected sequentially flows through the detection electrodes and the reference electrode, and the reference electrode and each detection electrode are respectively and electrically connected with the corresponding conductive piece; and

the electrolyte measuring component is connected with the conductive piece and obtains the ion concentration of the sample to be detected through the electric signal transmitted by the conductive piece;

the reference electrode is provided with a first accommodating cavity, the first accommodating cavity is used for accommodating a first internal reference solution to form a reference potential, and the orthographic projections of the first accommodating cavity and the at least two conductive pieces in the second direction are at least partially overlapped.

11. An electrolyte measuring mechanism for measuring an ion concentration of a sample to be tested, the electrolyte measuring mechanism comprising:

a mounting seat;

the conductive pieces are arranged on the mounting seat at intervals along a first direction;

the detection electrodes are arranged on the mounting seat and provided with second accommodating cavities for accommodating a second internal reference solution to form a membrane potential; and

the reference electrode is arranged on the mounting seat, the reference electrode and the plurality of detection electrodes are arranged along the first direction so that the sample to be detected sequentially flows through the detection electrodes and the reference electrode, and the reference electrode and each detection electrode are respectively and electrically connected with the corresponding conductive piece; and

the electrolyte measuring component is connected with the conductive piece and obtains the ion concentration of the sample to be detected through the electric signal transmitted by the conductive piece;

the reference electrode is provided with a first accommodating cavity, the first accommodating cavity is used for accommodating a first internal reference solution to form a reference potential, and the width of the first accommodating cavity in the first direction is two times or more than two times of the width of the second accommodating cavity in the first direction.

12. The electrolyte measurement mechanism of claim 11, wherein the width of the first receiving cavity in the first direction is four times or less than four times the width of the second receiving cavity in the first direction.

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