CN216687968U

CN216687968U - Immunoglobulin salting-out separation device for antibody production

Info

Publication number: CN216687968U
Application number: CN202220082475.XU
Authority: CN
Inventors: 陈旭华; 汪渊; 谌敦华
Original assignee: Shanghai Cymbal Poetry Biotechnology Co ltd
Current assignee: Shanghai Cymbal Poetry Biotechnology Co ltd
Priority date: 2022-01-13
Filing date: 2022-01-13
Publication date: 2022-06-07
Anticipated expiration: 2032-01-13

Abstract

The utility model discloses an immunoglobulin salting-out separation device for antibody production, which comprises a separation device tube, wherein a separation cap is arranged right above the separation device tube, connecting tubes are arranged in the separation device tube and the separation cap in a penetrating manner, and the tail ends of the connecting tubes are connected with a liquid outlet tube; the liquid inlet cap is arranged at the top end of the connecting pipe, a limiting plate is fixedly arranged inside the liquid inlet cap, and a limiting pipe is fixedly arranged at the bottom of the limiting plate at an equal angle; the separator box, the inside position at the separator pipe is installed to the separator box block, and the central point of separator box puts and has seted up spacing hole to the right-hand member in spacing hole is connected with spacing groove, the central point of separation cap puts and has seted up the carrier hole, the central point of feed liquor cap puts and has seted up the inlet. This immunoglobulin salting-out separator for antibody production not only can improve separation efficiency, conveniently assembles and dismantles this separator moreover.

Description

Immunoglobulin salting-out separation device for antibody production

Technical Field

The utility model relates to the technical field of antibody production, in particular to an immunoglobulin salting-out separation device for antibody production.

Background

Antibodies are immunoglobulins capable of binding specifically to antigens, the function of the antibodies is closely related to the structure of the antibodies, and differences in the function are determined by differences in the amino acid composition and sequence of the V region and the c region of the same antibody.

The immunoglobulin salting-out separation device for antibody production, which is commonly used at present, can not only improve the separation efficiency, but also is inconvenient to assemble and disassemble, so that the immunoglobulin salting-out separation device for antibody production is provided so as to solve the problems.

SUMMERY OF THE UTILITY MODEL

The present invention is directed to provide an immunoglobulin salting-out separator for antibody production, which solves the problems of the prior immunoglobulin salting-out separator for antibody production, which is not only unable to improve the separation efficiency, but also inconvenient to assemble and disassemble.

In order to achieve the purpose, the utility model provides the following technical scheme: an immunoglobulin salting-out separation device for antibody production, comprising:

the separation device comprises a separation device tube, a separation cap is arranged right above the separation device tube, connecting tubes are arranged in the separation device tube and the separation cap in a penetrating mode, and the tail ends of the connecting tubes are connected with a liquid outlet tube;

the liquid inlet cap is arranged at the top end of the connecting pipe, a limiting plate is fixedly arranged inside the liquid inlet cap, and a limiting pipe is fixedly arranged at the bottom of the limiting plate at an equal angle;

the separator box, the inside position at the separator pipe is installed to the separator box block, and the central point of separator box puts and has seted up spacing hole to the right-hand member in spacing hole is connected with spacing groove, the central point of separation cap puts and has seted up the carrier hole, the central point of feed liquor cap puts and has seted up the inlet.

Preferably, the separation device pipe and the separation cap are connected in a threaded manner, and the separation device pipe is of a hollow structure.

Preferably, the number of the connecting pipes is the same as that of the limiting pipes, and the central axes of the limiting pipes coincide with that of the connecting pipes.

Preferably, the length of the limiting pipe is sequentially increased from left to right, and the limiting pipe, the separating device pipe and the separating cap form a dismounting structure.

Preferably, the width of the liquid outlet pipe is sequentially increased from top to bottom, the maximum length of the liquid outlet pipe is smaller than the diameter of the bearing hole, and the liquid outlet pipe is tightly attached to the separation box.

Preferably, the height of the separation box is the same as the depth of the limiting hole, and the diameter of the limiting hole is the same as that of the bearing hole.

Compared with the prior art, the utility model has the following advantages:

1. a separation cap is arranged right above the separation device tube, connecting tubes are arranged in the separation device tube and the separation cap in a penetrating mode, the tail ends of the connecting tubes are connected with a liquid outlet tube, the separation device tube and the separation cap are connected in a threaded mode, the separation device tube and the separation cap can be conveniently separated, and the separation device is detached;

2. because the outer end of the connecting pipe is connected with the liquid outlet pipe, the salting-out liquid enters the separation box through the liquid inlet cap, the connecting pipe and the liquid outlet pipe, and the separation boxes are clamped inside the separation device pipe, so that the salting-out liquid can enter the separation boxes, and a plurality of parts of liquid to be detected are placed in the separation boxes, so that the separation efficiency can be improved;

3. the separation box is clamped in the separation device pipe, then the connecting pipe is inserted into the bearing hole formed in the center of the separation cap and the limiting hole formed in the center of the separation box, and then the limiting pipe arranged at the bottom of the liquid inlet cap is inserted into the connecting pipe, so that the separation device is convenient to assemble;

in conclusion, the immunoglobulin salting-out separation device for antibody production not only can improve the separation efficiency, but also is convenient to assemble and disassemble.

Drawings

FIG. 1 is a schematic view of the overall cutaway structure of the present invention;

FIG. 2 is a schematic view of the overall structure of the present invention;

FIG. 3 is a schematic view of the connection structure of the limiting hole and the limiting groove according to the present invention;

fig. 4 is a schematic view of the connection structure of the liquid inlet cap and the limiting plate.

In the figure: 1. a separator tube; 2. a separation cap; 3. a connecting pipe; 4. a liquid outlet pipe; 5. a liquid inlet cap; 6. a limiting plate; 7. a limiting pipe; 8. a separation tank; 9. a limiting hole; 10. a limiting groove; 11. a bearing hole; 12. and (4) a liquid inlet.

Detailed Description

The utility model is further described below with reference to the accompanying drawings:

as shown in the attached drawings 1 to 4, the utility model provides an immunoglobulin salting-out separation device for antibody production, which comprises a separation device tube 1, a liquid inlet cap 5 and a separation box 8, wherein the separation cap 2 is arranged right above the separation device tube 1, a connecting tube 3 is arranged in the separation device tube 1 and the separation cap 2 in a penetrating way, the tail end of the connecting tube 3 is connected with a liquid outlet tube 4, the width of the liquid outlet tube 4 is increased from top to bottom in sequence, the maximum length of the liquid outlet tube 4 is smaller than the diameter of a bearing hole 11, the liquid outlet tube 4 is tightly attached to the separation box 8, the separation device tube 1 and the separation cap 2 are connected in a threaded manner in figure 1, the separation device is convenient to disassemble, the separation box 8 is clamped in the separation device tube 1 in figure 3, the length of a limiting tube 7 is increased from left to right in sequence, and the limiting tube 7 and the separation device tube 1 and the separation cap 2 form a disassembling structure, then, the connecting pipe 3 is inserted into a bearing hole 11 formed in the center of the separating cap 2 and a limiting hole 9 formed in the center of the separating box 8, and then a limiting pipe 7 arranged at the bottom of a limiting plate 6 arranged in the liquid inlet cap 5 in the figure 4 is inserted into the connecting pipe 3, so that the separating device is convenient to assemble;

because the outer end of the connecting pipe 3 is connected with the liquid outlet pipe 4, the liquid outlet pipe 4 is inserted into the separation box 8 when the salting-out device is used, the liquid inlet 12 formed in the center of the liquid inlet cap 5 facilitates the salting-out liquid to enter, the salting-out liquid enters the separation box 8 through the liquid inlet cap 5, the connecting pipe 3 and the liquid outlet pipe 4, the liquid to be detected is added into the separation box 8, the salting-out liquid can enter a plurality of separation boxes 8, and the separation efficiency is improved;

the inside trough-shaped structure of separator box 8 can place detection liquid, with 3 blocks of connecting pipe in spacing groove 10, conveniently takes off separator box 8, clears up separator box 8, and the connected mode between separator box 8 and the separator pipe 1 is connected for the block, conveniently dismantles between separator pipe 1 and the separator box 8, and this is exactly this whole course of operation of immunoglobulin salting-out separator for antibody production.

Those not described in detail in this specification are within the skill of the art. The standard parts used in the utility model can be purchased from the market, the special-shaped parts can be customized according to the description and the description of the attached drawings, the specific connection mode of each part adopts the conventional means such as mature bolts, rivets, welding and the like in the prior art, the machines, parts and equipment adopt the conventional models in the prior art, and the circuit connection adopts the conventional connection mode in the prior art, so the detailed description is omitted.

The present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents and are included in the scope of the present invention.

Claims

1. An immunoglobulin salting-out separation device for antibody production, comprising:

the separation device comprises a separation device tube (1), a separation cap (2) is arranged right above the separation device tube (1), connecting tubes (3) are arranged in the separation device tube (1) and the separation cap (2) in a penetrating mode, and the tail ends of the connecting tubes (3) are connected with liquid outlet tubes (4);

the liquid inlet cap (5) is arranged at the top end of the connecting pipe (3), a limiting plate (6) is fixedly arranged inside the liquid inlet cap (5), and a limiting pipe (7) is fixedly arranged at the bottom of the limiting plate (6) at an equal angle;

separation box (8), separation box (8) block is installed in the inside position of separator pipe (1), and the central point of separation box (8) puts and has seted up spacing hole (9) to the right-hand member of spacing hole (9) is connected with spacing groove (10), the central point of separation cap (2) puts and has seted up bearing hole (11), the central point of feed liquor cap (5) puts and has seted up inlet (12).

2. The immunoglobulin salting-out separation device for antibody production according to claim 1, wherein: the separation device pipe (1) is connected with the separation cap (2) in a threaded manner, and the separation device pipe (1) is of a hollow structure.

3. The immunoglobulin salting-out separation device for antibody production according to claim 1, wherein: the number of the connecting pipes (3) is the same as that of the limiting pipes (7), and the central axes of the limiting pipes (7) are superposed with the central axes of the connecting pipes (3).

4. The immunoglobulin salting-out separation device for antibody production according to claim 1, wherein: the length of the limiting pipe (7) is sequentially increased from left to right, and the disassembling structures are formed between the limiting pipe (7) and the separating device pipe (1) and between the limiting pipe and the separating cap (2).

5. The immunoglobulin salting-out separation device for antibody production according to claim 1, wherein: the width of drain pipe (4) increases from top to bottom in proper order, and the maximum length of drain pipe (4) is less than the diameter that bears hole (11) to closely laminate between drain pipe (4) and separator box (8).

6. The immunoglobulin salting-out separation device for antibody production according to claim 1, wherein: the height of the separation box (8) is the same as the depth of the limiting hole (9), and the diameter of the limiting hole (9) is the same as that of the bearing hole (11).