CN212864789U

CN212864789U - Medicine cell culture device

Info

Publication number: CN212864789U
Application number: CN202021260787.2U
Authority: CN
Inventors: 龚阿芳; 李志伟; 王婷婷
Original assignee: Zhengzhou Shuqing Medical College
Current assignee: Zhengzhou Shuqing Medical College
Priority date: 2020-06-24
Filing date: 2020-06-24
Publication date: 2021-04-02
Anticipated expiration: 2030-06-24

Abstract

The utility model discloses a medicine cell culture device, concretely relates to cell culture device technical field, the power distribution box comprises a box body, well slab in the inside fixedly connected with of box, box front side fixedly connected with glass window, the glass window is located well slab top, box inner chamber bottom fixedly connected with refrigerator, the inside moving mechanism that is equipped with of box. The utility model discloses a rotate the handle, thereby drive screw cap rebound, when the screw cap removed to two baffle bottoms, the screw cap continued rebound to drive two baffle removals mutually, the spring compression, observe the growth condition of cell in the culture dish through the glass window, when needs storage cell, thereby the reversal handle drives the culture dish and removes to well cavity bottom plate, start the refrigerator, refrigerator work produces air conditioning, the cell to in the culture dish is cold-stored, the cell after the convenience is cultivateed is saved, conveniently observe the growth condition of cell simultaneously.

Description

Medicine cell culture device

Technical Field

The utility model relates to a cell culture device technical field, concretely relates to medicine and pharmacology cell culture device.

Background

Cell culture is also called cell cloning technology, the formal term in biology is cell culture technology, and cell culture is an essential process for the whole bioengineering technology and one of the biotechnology, the cell culture is large-scale cell cloning, the cell culture technology can be used for culturing a large amount of cells into simple single cells or cells with few differentiation, which is an essential link of the cloning technology, and the cell culture is cell cloning, the cell culture refers to all in vitro culture, and means that tissues are taken out from a living organism of an animal, and the tissues are incubated and cultured under specific in vivo conditions such as simulated in vivo physiological environment, so that the tissues are survived and grown.

The existing medical cell culture device only has the function of culturing cells, can not store the cultured cells, and is inconvenient for observing the growth condition of the cells in a culture dish.

SUMMERY OF THE UTILITY MODEL

Therefore, the embodiment of the utility model provides a medicine and pharmacology cell culture device, through rotating the handle, thereby drive screw cap rebound, when screw cap removes to two baffle bottoms, screw cap continues to rebound and drives two baffle removal mutually in the back of the body, spring compression, observe the growth condition of cell in the culture dish through the glass window, when needs storage cell, thereby the reversal handle drives the culture dish and removes to well cavity bottom plate, start the refrigerator, refrigerator work produces air conditioning, cell to in the culture dish is cold-stored, conveniently save the cell after the cultivation, conveniently observe the growth condition of cell simultaneously, with the problem that can not store the cell among the solution prior art.

In order to achieve the above object, the embodiment of the present invention provides the following technical solutions: a medical cell culture device comprises a box body, wherein a hollow plate is fixedly connected inside the box body, a glass window is fixedly connected to the front side of the box body and positioned at the top end of the hollow plate, a refrigerator is fixedly connected to the bottom of an inner cavity of the box body, and a moving mechanism is arranged inside the box body;

the moving mechanism comprises a storage plate which is positioned at the bottom of the hollow plate, a plurality of dish storage grooves are arranged at the top end of the storage plate, the top of the object placing plate is provided with a plurality of culture dishes, the bottom ends of the culture dishes extend into the dish placing grooves at corresponding positions respectively, the top of each culture dish is provided with a threaded cap, the threaded caps are connected with the culture dishes at corresponding positions respectively through threads, the top end and the bottom end of the hollow plate are both provided with two first through grooves, the plurality of screw caps are respectively positioned under the first through grooves at corresponding positions, four baffles are arranged inside the hollow plate, three springs are arranged inside the hollow plate, wherein the two baffles are locked with the box body through springs, the other two baffles are locked with the box body through springs, the top of the inner cavity of the box body is fixedly connected with a liquid storage frame, and the bottom of the liquid storage frame is fixedly connected with a plurality of liquid guide pipes.

Furthermore, a plurality of second through grooves are formed in the top ends of the thread caps, and the second through grooves are respectively located right below the liquid guide pipes in corresponding positions.

Furthermore, a liquid inlet is formed in the top end of the box body, a box cover is arranged inside the liquid inlet, and the box cover and the box body are locked through a hasp.

Further, the chutes are formed in two side walls of the inner cavity of the box body, the chutes are respectively provided with a slide bar and a threaded rod inside the chutes, the slide bar is fixedly connected with the box body, and two ends of the threaded rod are movably connected with the box body through bearings.

Furthermore, the outer peripheral face of the sliding rod is sleeved with a sliding sleeve, and the sliding sleeve is fixedly connected with the object placing plate.

Further, threaded rod outer peripheral face cover is equipped with the thread bush, just thread bush and threaded rod threaded connection, the thread bush with put thing board fixed connection.

Furthermore, a first bevel gear is sleeved on the outer peripheral surface of the threaded rod, a second bevel gear is arranged on one side of the first bevel gear, and the second bevel gear is meshed with the first bevel gear.

Further, second bevel gear one side fixedly connected with pivot, box one side is equipped with the handle, the one end that second bevel gear was kept away from in the pivot runs through box one side and with handle fixed connection.

Furthermore, a box door is arranged on the front side of the box body, the box door is connected with the box body through a hinge, and the box door is located at the bottom end of the hollow plate.

The utility model has the advantages of as follows:

the utility model discloses a rotate the handle, thereby it moves up to drive puts the thing board, and then drive the screw cap and move up, when the screw cap moves to two baffle bottoms, the screw cap continues to move up and drives two baffle back of the body and move, spring compression, when the catheter passes second logical groove and gets into in the culture dish, take off the hasp and remove the locking between case lid and the box, and add nutrient solution to the inlet port, nutrient solution falls into the stock solution frame, and flow into the culture dish through the catheter, observe the growth condition of cell in the culture dish through the glass window, when needing to store the cell, reverse handle thereby drive the culture dish and move to well hollow plate bottom, spring-back drives two baffles and moves in opposite directions simultaneously, start the refrigerator, the refrigerator work produces air conditioning, refrigerate the cell in the culture dish, compared with the prior art, conveniently store the cell after the cultivation, meanwhile, the growth condition of the cells is convenient to observe.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. It should be apparent that the drawings in the following description are merely exemplary, and that other embodiments can be derived from the drawings provided by those of ordinary skill in the art without inventive effort.

The structure, ratio, size and the like shown in the present specification are only used for matching with the content disclosed in the specification, so as to be known and read by people familiar with the technology, and are not used for limiting the limit conditions which can be implemented by the present invention, so that the present invention has no technical essential significance, and any structure modification, ratio relationship change or size adjustment should still fall within the scope which can be covered by the technical content disclosed by the present invention without affecting the efficacy and the achievable purpose of the present invention.

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a sectional view of the overall structure of the present invention;

FIG. 3 is an enlarged view of the structure A in FIG. 2 according to the present invention;

FIG. 4 is an enlarged view of the structure B in FIG. 2 according to the present invention;

FIG. 5 is a perspective view of the object placing plate of the present invention;

in the figure: the refrigerator comprises a box body 1, a hollow plate 2, a baffle plate 3, a threaded rod 4, a threaded cap 5, a refrigerator 6, a culture dish 7, an object placing plate 8, a sliding rod 9, a sliding sleeve 10, a sliding groove 11, a spring 12, a dish placing groove 13, a first through groove 14, a liquid guide pipe 15, a box cover 16, a liquid storage frame 17, a box door 18, a glass window 19, a first bevel gear 20, a threaded sleeve 21, a second bevel gear 22, a rotating shaft 23, a handle 24 and a second through groove 25.

Detailed Description

The present invention is described in terms of specific embodiments, and other advantages and benefits of the present invention will become apparent to those skilled in the art from the following disclosure. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to the attached drawings 1-5 of the specification, the pharmaceutical cell culture device of the embodiment comprises a box body 1, a hollow plate 2 is fixedly connected inside the box body 1, a glass window 19 is fixedly connected to the front side of the box body 1, the glass window 19 is positioned at the top end of the hollow plate 2, a refrigerator 6 is fixedly connected to the bottom of the inner cavity of the box body 1, a moving mechanism is arranged inside the box body 1, the moving mechanism comprises a storage plate 8, the storage plate 8 is positioned at the bottom of the hollow plate 2, a plurality of dish placing grooves 13 are formed in the top end of the storage plate 8, a plurality of culture dishes 7 are arranged on the top of the storage plate 8, the bottom ends of the culture dishes 7 respectively extend into the dish placing grooves 13 at corresponding positions, threaded caps 5 are arranged on the tops of the culture dishes 7, the threaded caps 5 are respectively in threaded connection with the culture dishes 7 at corresponding positions, two first through grooves 14 are formed in the top end and the bottom end of the, a plurality of screw cap 5 is located under corresponding position's first logical groove 14 respectively, the inside four baffles 3 that are equipped with of well hollow plate 2, the inside three spring 12 that is equipped with of well hollow plate 2, wherein two all lock mutually through spring 12 between baffle 3 and the box 1, wherein two in addition lock mutually through spring 12 between the baffle 3, 1 inner chamber top fixedly connected with stock solution frame 17 of box, a plurality of catheter 15 of stock solution frame 17 bottom fixedly connected with.

Furthermore, a plurality of second through grooves 25 are formed in the top ends of the screw caps 5, and the plurality of second through grooves 25 are respectively located right below the liquid guide pipes 15 at corresponding positions, so that the liquid guide pipes 15 can conveniently extend into the culture dish 7.

Furthermore, a liquid inlet is formed in the top end of the box body 1, a box cover 16 is arranged inside the liquid inlet, and the box cover 16 and the box body 1 are locked through a hasp, so that nutrient solution can be added conveniently.

Further, 1 inner chamber both sides wall of box has all been seted up spout 11, two spout 11 is inside to be equipped with slide bar 9 and threaded rod 4 respectively,

slide bar

9 and 1 fixed connection of box, 4 both ends of threaded rod pass through bearing swing joint with box 1, conveniently put thing board 8 rebound.

Furthermore, the sliding sleeve 10 is sleeved on the outer peripheral surface of the sliding rod 9, the sliding sleeve 10 is fixedly connected with the object placing plate 8, and the object placing plate 8 can move upwards conveniently.

Further, 4 outer peripheral face covers of threaded rod are equipped with thread bush 21, just

thread bush

21 and 4 threaded connection of threaded rod, thread bush 21 with put thing board 8 fixed connection, conveniently drive and put thing board 8 and remove.

Furthermore, the outer peripheral surface of the threaded rod 4 is sleeved with a first bevel gear 20, one side of the first bevel gear 20 is provided with a second bevel gear 22, and the second bevel gear 22 is meshed with the first bevel gear 20, so that the threaded rod 4 is conveniently driven to rotate.

Further, a rotating shaft 23 is fixedly connected to one side of the second bevel gear 22, a handle 24 is arranged on one side of the box body 1, and one end, far away from the second bevel gear 22, of the rotating shaft 23 penetrates through one side of the box body 1 and is fixedly connected with the handle 24, so that the second bevel gear 22 can be conveniently driven to rotate.

Further, the front side of the box body 1 is provided with a box door 18, the box door 18 is connected with the box body 1 through a hinge, and the box door 18 is positioned at the bottom end of the hollow plate 2, so that the culture dish 7 in the box body 1 can be conveniently taken out.

The implementation scenario is specifically as follows: the staff rotates the handle 24 to drive the rotating shaft 23 to rotate and further drive the second bevel gear 22 to rotate, since the second bevel gear 22 is meshed with the first bevel gear 20, the second bevel gear 22 rotates to drive the first bevel gear 20 to rotate and further drive the threaded rod 4 to rotate, since the threaded rod 4 is in threaded connection with the threaded sleeve 21 and the chute 11 limits the rotation of the threaded sleeve 21, the threaded rod 4 rotates to drive the threaded sleeve 21 to move upwards so as to drive the object placing plate 8 to move upwards and further drive the threaded cap 5 to move upwards, and simultaneously the object placing plate 8 moves upwards to drive the sliding sleeve 10 to slide on the sliding rod 9, so that the object placing plate 8 can move upwards conveniently, when the threaded cap 5 moves to the bottoms of the two baffles 3, the threaded cap 5 continues to move upwards to drive the two baffles 3 to move away from each other and the spring 12 to compress, when the liquid guide tube 15 passes through the second through groove 25 to enter the culture dish 7, the, add the nutrient solution in the inlet port, the nutrient solution falls into stock solution frame 17, and flow into culture dish 7 through catheter 15, conveniently add the nutrient solution, observe the growth condition of cell in culture dish 7 through glass window 19, when needs storage cell, thereby reversal handle 24 drives culture dish 7 and removes to hollow plate 2 bottoms, spring 12 kick-backs simultaneously and drives two baffles 3 and remove in opposite directions, start

refrigerator

6, 6 work of refrigerator produce air conditioning, cell to in culture dish 7 is refrigerated, conveniently store the cell after the cultivation, open 18 convenient culture dishes 7 of taking out in the box 1 of chamber door, the problem that can not store the cell among the prior art has specifically been solved to this embodiment.

The working principle is as follows:

referring to the attached drawings 1-5 of the specification, a worker rotates the handle 24 to drive the object placing plate 8 to move upwards and further drive the threaded cap 5 to move upwards, when the threaded cap 5 moves to the bottoms of the two baffle plates 3, the threaded cap 5 continues to move upwards to drive the two baffle plates 3 to move back and forth, the spring 12 compresses, the growth condition of cells in the culture dish 7 is observed through the glass window 19, when the cells need to be stored, the handle 24 is reversed to drive the culture dish 7 to move to the bottom of the hollow plate 2, the refrigerator 6 is started, the refrigerator 6 works to generate cold air, and the cells in the culture dish 7 are refrigerated.

Although the invention has been described in detail with respect to the general description and the specific embodiments, it will be apparent to those skilled in the art that modifications and improvements can be made based on the invention. Therefore, such modifications and improvements are intended to be within the scope of the invention as claimed.

Claims

1. A pharmaceutical and pharmacologic cell culture device comprises a box body (1) and is characterized in that: the refrigerator is characterized in that a hollow plate (2) is fixedly connected inside the box body (1), a glass window (19) is fixedly connected to the front side of the box body (1), the glass window (19) is located at the top end of the hollow plate (2), a refrigerator (6) is fixedly connected to the bottom of an inner cavity of the box body (1), and a moving mechanism is arranged inside the box body (1);

the moving mechanism comprises an object placing plate (8), the object placing plate (8) is positioned at the bottom of a hollow plate (2), a plurality of dish placing grooves (13) are formed in the top end of the object placing plate (8), a plurality of culture dishes (7) are arranged at the top of the object placing plate (8), the bottoms of the culture dishes (7) extend into the dish placing grooves (13) at corresponding positions respectively, threaded caps (5) are arranged at the tops of the culture dishes (7), the threaded caps (5) are in threaded connection with the culture dishes (7) at corresponding positions respectively, two first through grooves (14) are formed in the top end and the bottom end of the hollow plate (2), the threaded caps (5) are positioned under the first through grooves (14) at corresponding positions respectively, four baffles (3) are arranged inside the hollow plate (2), three springs (12) are arranged inside the hollow plate (2), wherein the two baffles (3) are locked with a box body (1) through the springs (12), the other two baffles (3) are locked by springs (12), the top of the inner cavity of the box body (1) is fixedly connected with a liquid storage frame (17), and the bottom end of the liquid storage frame (17) is fixedly connected with a plurality of liquid guide pipes (15).

2. A pharmaceutical cell culture apparatus according to claim 1, wherein: the top ends of the plurality of threaded caps (5) are provided with second through grooves (25), and the plurality of second through grooves (25) are respectively positioned under the liquid guide pipes (15) at corresponding positions.

3. A pharmaceutical cell culture apparatus according to claim 1, wherein: a liquid inlet is formed in the top end of the box body (1), a box cover (16) is arranged inside the liquid inlet, and the box cover (16) and the box body (1) are locked through a hasp.

4. A pharmaceutical cell culture apparatus according to claim 1, wherein: the box (1) inner chamber both sides wall has all seted up spout (11), two spout (11) are inside to be equipped with slide bar (9) and threaded rod (4) respectively, slide bar (9) and box (1) fixed connection, bearing swing joint is passed through with box (1) in threaded rod (4) both ends.

5. A device according to claim 4, wherein: the sliding rod (9) is sleeved with a sliding sleeve (10) on the outer peripheral surface, and the sliding sleeve (10) is fixedly connected with the object placing plate (8).

6. A device according to claim 4, wherein: threaded rod (4) outer peripheral face cover is equipped with thread bush (21), just thread bush (21) and threaded rod (4) threaded connection, thread bush (21) with put thing board (8) fixed connection.

7. A device according to claim 4, wherein: the outer peripheral surface of the threaded rod (4) is sleeved with a first bevel gear (20), one side of the first bevel gear (20) is provided with a second bevel gear (22), and the second bevel gear (22) is meshed with the first bevel gear (20).

8. A pharmaceutical cell culture apparatus according to claim 7, wherein: second bevel gear (22) one side fixedly connected with pivot (23), box (1) one side is equipped with handle (24), the one end that second bevel gear (22) were kept away from in pivot (23) runs through box (1) one side and with handle (24) fixed connection.

9. A pharmaceutical cell culture apparatus according to claim 1, wherein: the refrigerator is characterized in that a refrigerator door (18) is arranged on the front side of the refrigerator body (1), the refrigerator door (18) is connected with the refrigerator body (1) through a hinge, and the refrigerator door (18) is located at the bottom end of the hollow plate (2).