CN208921621U - A kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers - Google Patents
A kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers Download PDFInfo
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- CN208921621U CN208921621U CN201821706522.3U CN201821706522U CN208921621U CN 208921621 U CN208921621 U CN 208921621U CN 201821706522 U CN201821706522 U CN 201821706522U CN 208921621 U CN208921621 U CN 208921621U
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Abstract
The utility model discloses a kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers, the miniflow hole retained including Hollow-Core Photonic Crystal Fibers, covering airport blocks central aperture, side microchannel, multimode fibre；In Hollow-Core Photonic Crystal Fibers left end, technique is collapsed using the selectivity that heat sealing machine discharges, prepare the miniflow hole of covering airport blocks central aperture reservation, fs-laser system is reused to punch in Hollow-Core Photonic Crystal Fibers side, obtain side microchannel, Hollow-Core Photonic Crystal Fibers right end and multimode fibre are finally subjected to welding using heat sealing machine, miniflow detector is made；When having fluorescent molecule solution to flow through in Hollow-Core Photonic Crystal Fibers microchannel and by ultraviolet excitation, fluorescence signal is transmitted to receiver by multimode fibre, and the intensity and wavelength of analysis of fluorescence signal realize the real-time detection to fluorescent molecule SOLUTION PROPERTIES.The device signal-to-noise ratio height, high sensitivity, detectable limit are low.
Description
Technical field
The utility model belongs to miniflow detection technique field, in particular to a kind of based on selection filling hollow photon crystal light
Fine fluorescent chemicals miniflow detector.
Background technique
Compound launches light longer than excitation wavelength, referred to as fluorescence after by ultraviolet excitation；It is absorbed by compound
Light be known as exciting light, the fluorescence of generation is known as emitting light.The wavelength of fluorescence is always longer than the ultraviolet wavelength of molecule absorption, leads to
Often in visible-range.After the property and molecular structure of fluorescence have substantial connection, the molecule of different structure to be excited, it is not
Fluorescence can be emitted.Currently, experimental study of each research institution to fluorescent chemicals, is mainly completed using fluorescence detector.This
The shortcomings that kind detector is that system cost is high, volume is big, and fluorescence must occur under selected conditions for biological analyte,
It is very sensitive to some interference in fluorescence measurement.
Fibre optical sensor has many advantages, such as small in size, speed is fast, processing capability in real time is strong, high sensitivity, especially
Fiber optic materials have good bioaffinity, small to living injury, will not cause rejection, be very suitable for biomedical inspection
The application such as survey and clinical medicine diagnosis.Since the fluorescence signal received can be almost sent to without loss spectrum analysis by optical fiber
In instrument, and the optical transmission pathway of its " closing " formula rings fluorescence signal from environment shadow, therefore, the fluorescence inspection based on optical fiber
Survey technology has signal-to-noise ratio height, the advantage of high sensitivity.With the development of micro-processing technology, in Hollow-Core Photonic Crystal Fibers
Realize that selective filling further improves the flexibility of element manufacturing in special air hole.Hollow-Core Photonic Crystal Fibers are flexibly tied
Structure and material parameter can meet the fluorescence detection of any wave band and solution properties, and good design is flexible and prepares controllability,
It has a good application prospect in terms of bio-sensing.
Summary of the invention
Mainly utilize the height of cost caused by fluorescence detector, volume big, easy for the detection currently based on fluorescent chemicals
The deficiencies of being disturbed, the purpose of this utility model is to provide a kind of structures, and simple, small in size, at low cost, required sample is few
Fluorescent chemicals detector, it is actually detected to have the characteristics that high sensitivity, high s/n ratio, using flexible.The all optical fibre structure
Solution needed for senser element is nanoliter (nL) magnitude, and high performance detector can be made.
In order to achieve the above object, the technical scheme adopted by the utility model is a kind of be based on Hollow-Core Photonic Crystal Fibers
Fluorescent chemicals miniflow detector include Hollow-Core Photonic Crystal Fibers, covering airport blocks central aperture retain miniflow hole,
Side microchannel, multimode fibre；In Hollow-Core Photonic Crystal Fibers left end, technique is collapsed using the selectivity that heat sealing machine discharges,
Hollow-Core Photonic Crystal Fibers side is burnt using fs-laser system in the miniflow hole for preparing the reservation of covering airport blocks central aperture
Erosion obtains side microchannel until running through entire cladding regions, finally utilizes burning-on method by Hollow-Core Photonic Crystal Fibers right end
Welding is carried out with multimode fibre, obtains miniflow detector；When there is fluorescent molecule solution in Hollow-Core Photonic Crystal Fibers microchannel
Flow through and when by ultraviolet excitation, fluorescence signal is transmitted to receiver by multimode fibre, the intensity of analysis of fluorescence signal and
Wavelength realizes the real-time detection to fluorescent molecule SOLUTION PROPERTIES.
The central wavelength of Hollow-Core Photonic Crystal Fibers described in the utility model be 1550nm, 120 μm of cladding diameter, fibre core
10 μm of diameter.
The miniflow hole that the covering airport blocks central aperture described in the utility model retains is by hollow photon crystal
Crystal optical fibre one end, which collapses technique using the selectivity that heat sealing machine discharges, makes covering airport close to obtain.
Side microchannel described in the utility model is formed by femtosecond laser parallel micromachining, laser frequency 50fs, and wavelength is
800nm。
The cladding diameter of the multimode fibre described in the utility model is 125 μm, and core diameter is 62.5 μm.
The beneficial effects of the utility model are: proposing for all optical fibre structure sensor-based system to be applied to the inspection of fluorescent chemicals miniflow
In survey technology, the miniflow hole that Hollow-Core Photonic Crystal Fibers covering airport blocks central aperture is retained is as fluorescent chemicals solution
The fluorescence field of microchannel, outgoing is overlapped with the mould field of optical fiber transmission mould, is substantially increased the coupling efficiency of fluorescence and optical fiber, is mentioned
Required sample size is reduced to nanoliter (nL) magnitude while rising detection sensitivity, is provided for fluorescent chemicals miniflow detection technique
It is a kind of it is at low cost, signal-to-noise ratio is high, the new method of high sensitivity, there is important research in terms of biomedical and drug screening
Meaning.
Detailed description of the invention
Fig. 1 is the miniflow detector of the utility model.
Fig. 2 is a kind of fluorescent chemicals miniflow detector feature dress based on Hollow-Core Photonic Crystal Fibers of the utility model
Set schematic diagram.
Specific embodiment
The utility model is described in further detail with specific embodiment with reference to the accompanying drawing.
Referring to two kinds of different optical fiber in attached drawing 1, the miniflow hole (2) of covering airport blocks central aperture reservation is to use
Optical fiber splicer setup parameter is formed.The processing of side microchannel (3) uses the femtosecond laser of pulsewidth 50fs, wavelength 800nm
System is focused on Hollow-Core Photonic Crystal Fibers (1) surface by the mirror of high-NA, and Hollow-Core Photonic Crystal Fibers (1) are logical
It crosses fiber clamp to be fixed on high-precision three-dimensional electromigration platform, by being gradually increasing for electromigration platform, focuses on laser hollow
Depth is gradually deepened in photonic crystal fiber (1), until running through entire cladding regions, constructs side miniflow hole, hollow photon
Crystal optical fibre (1) is welded together with multimode fibre (4) by heat sealing machine, and miniflow detector is made.
Referring to Experimental equipment in attached drawing 2, the central wavelength of ultraviolet LED is 320nm.Hollow-Core Photonic Crystal Fibers (1) are right
End links together with multimode fibre (4) left end, and multimode fibre (4) right end is connect with the input port of circulator (5), circulator
(5) delivery outlet is connect with ultraviolet LED light source (7), and the isolated port of circulator (5) is connected with spectroanalysis instrument (6)；It is hollow
One glass of surveyed solution is placed in the left end of photonic crystal fiber (1), so that fluorescent chemicals solution is entered miniflow by capillary phenomenon logical
Road, ultraviolet LED light source (7) is coupled into multimode fibre by circulator (5), in microchannel in a manner of end pumping
Fluorescent chemicals are excited, and the fluorescence signal that fluorescent molecule is launched enters transmission fiber in a manner of acquiring backward and by light
Spectrum analysis instrument (6) detection receives.Fluorescence stimulation effect, detection sensitivity, signal strength, signal-to-noise ratio etc. are studied, is realized Fluoresceinated
The real-time detection of polymer solution property.
Claims (5)
1. a kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers, it is characterised in that the hollow photon crystal
The fluorescent chemicals miniflow detector of optical fiber includes that Hollow-Core Photonic Crystal Fibers (1), covering airport blocks central aperture retain
Miniflow hole (2), side microchannel (3), multimode fibre (4)；In Hollow-Core Photonic Crystal Fibers (1) left end, put using heat sealing machine
The selectivity of electricity collapses technique, prepares the miniflow hole (2) of covering airport blocks central aperture reservation, utilizes fs-laser system pair
Hollow-Core Photonic Crystal Fibers (1) side ablation obtains side microchannel (3), finally utilizes until running through entire cladding regions
The right end of Hollow-Core Photonic Crystal Fibers (1) and multimode fibre (4) are carried out welding by burning-on method, obtain miniflow detector；When hollow
There is fluorescent molecule solution to flow through in photonic crystal fiber microchannel and when by ultraviolet excitation, fluorescence signal passes through multimode light
Fine (4) are transmitted to receiver, and the intensity and wavelength of analysis of fluorescence signal realize the real-time detection to fluorescent molecule SOLUTION PROPERTIES.
2. a kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers according to claim 1, special
Sign is: Hollow-Core Photonic Crystal Fibers (1) be center wavelength 1550nm, 120 μm of cladding diameter, 10 μm of core diameter.
3. a kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers according to claim 1, special
Sign is: the miniflow hole (2) that the covering airport blocks central aperture retains is utilized by Hollow-Core Photonic Crystal Fibers (1) one end
The selectivity of heat sealing machine electric discharge, which collapses technique, makes covering airport close to obtain.
4. a kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers according to claim 1, special
Sign is: the side microchannel (3) is formed by femtosecond laser parallel micromachining, laser frequency 50fs, wavelength 800nm.
5. a kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers according to claim 1, special
Sign is: the cladding diameter of multimode fibre (4) is 125 μm, and core diameter is 62.5 μm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821706522.3U CN208921621U (en) | 2018-10-22 | 2018-10-22 | A kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821706522.3U CN208921621U (en) | 2018-10-22 | 2018-10-22 | A kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers |
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| CN201821706522.3U Active CN208921621U (en) | 2018-10-22 | 2018-10-22 | A kind of fluorescent chemicals miniflow detector based on Hollow-Core Photonic Crystal Fibers |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110274884A (en) * | 2019-06-28 | 2019-09-24 | 天津理工大学 | Bimolecular sensors based on photo-thermal micro-fluidic in microstructured optical fibers |
| CN111229336A (en) * | 2020-01-17 | 2020-06-05 | 上海新微技术研发中心有限公司 | Method for manufacturing optical waveguide multi-micro-channel chip |
| CN114755188A (en) * | 2022-05-19 | 2022-07-15 | 华北电力大学 | All-fiber probe for dissolved gas in-situ detection without liquid-gas separation |
-
2018
- 2018-10-22 CN CN201821706522.3U patent/CN208921621U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110274884A (en) * | 2019-06-28 | 2019-09-24 | 天津理工大学 | Bimolecular sensors based on photo-thermal micro-fluidic in microstructured optical fibers |
| CN111229336A (en) * | 2020-01-17 | 2020-06-05 | 上海新微技术研发中心有限公司 | Method for manufacturing optical waveguide multi-micro-channel chip |
| CN111229336B (en) * | 2020-01-17 | 2021-11-23 | 上海新微技术研发中心有限公司 | Method for manufacturing optical waveguide multi-micro-channel chip |
| CN114755188A (en) * | 2022-05-19 | 2022-07-15 | 华北电力大学 | All-fiber probe for dissolved gas in-situ detection without liquid-gas separation |
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