CN208395171U - A kind of biopharmaceutical liquids material transmitting isolating and protecting device - Google Patents
A kind of biopharmaceutical liquids material transmitting isolating and protecting device Download PDFInfo
- Publication number
- CN208395171U CN208395171U CN201820822955.9U CN201820822955U CN208395171U CN 208395171 U CN208395171 U CN 208395171U CN 201820822955 U CN201820822955 U CN 201820822955U CN 208395171 U CN208395171 U CN 208395171U
- Authority
- CN
- China
- Prior art keywords
- stainless steel
- steel sleeve
- protecting device
- sleeve pipe
- isolating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The utility model discloses a kind of biopharmaceutical liquids materials to transmit isolating and protecting device, and the biopharmaceutical liquids material transmitting isolating and protecting device constitutes as follows: stainless steel sleeve pipe (1), seal assembly (2), pressure gauge (3), the first material transfer pipe (4), the second material transfer pipe (5), elastic packing plate (6), air supply pipeline (7), pure steam pipeline (8), the first diaphragm valve (9) and the second diaphragm valve (10)；Wherein, the stainless steel sleeve pipe (1) passes through wall (11) and is connected on wall (11); pressure gauge (3) is connected on stainless steel sleeve pipe (1); the application of the biopharmaceutical liquids material transmitting isolating and protecting device reduces a large amount of transferring case; and isolation air-lock; reduce the setting of sterilizer; reduce that container is temporary, cleaning area; reduce construction investment; reduce cleaning, the personnel in sterilizing post prepare, reduction energy consumption and operating cost.
Description
Technical field
The utility model relates to the design of the structure of bio-pharmaceuticals transfer device and applied technical fields, specifically provide one kind
Biopharmaceutical liquids material transmits isolating and protecting device.
Background technique
Bio-pharmaceuticals be using biotechnology exploitation, research, production drug process, be the except chemical drugs, Chinese medicine
Three big mold of drug development are the development fields that country promotes emphasis.Bio-pharmaceuticals, especially biological products are thin using biology
Born of the same parents, microculture are prepared with the biological products of medical usage, and the outstanding feature of production process and production management is: production ring
Border purity requirements are high, with the presence of virus, germ, biological cell isoreactivity biology, are also easy to produce cross contamination, are to belong to technology to contain
Amount is high, the high-tech industry that investment is high, risk is high, return is high.So the anti-pollution and sterility protection of production process is to ensure life
The important means of object pharmacy quality is the key takeaway of GMP management.Material will exist according to process flow during pharmaceutical manufacturing
It is mutually transmitted between the different other production districts of clean grade, in order to shorten conveying distance, technological design scheme is as far as possible by site of delivery
Be located at a wall every but there is still a need for punching for Pipeline Crossing Program on the dividing wall of different clean area, it is clean that this will lead to two differences
The air-flow in net rank region intersects, to generate cross contamination, pharmaceutical production quality is seriously threatened, so the nothing of bio-pharmaceuticals
Bacterium protection, cleaning are isolated, prevent cross contamination from being bio-pharmaceuticals production technology, the core of quality management and industry certification is asked
Topic.
People are highly desirable to obtain a kind of biopharmaceutical liquids material that technical effect is excellent transmitting isolating and protecting device.
Utility model content
The purpose of the utility model is to provide a kind of biopharmaceutical liquids materials to transmit isolating and protecting device.
The biopharmaceutical liquids material transmitting isolating and protecting device constitutes as follows: stainless steel sleeve pipe 1, seal assembly 2, pressure
Power table 3, the first material transfer pipe 4, the second material transfer pipe 5, elastic packing plate 6, air supply pipeline 7, pure steam pipeline 8, the first diaphragm valve 9,
Second diaphragm valve 10；Wherein, the stainless steel sleeve pipe 1 passes through wall 11 and is connected on wall 11, and pressure gauge 3 is connected to stainless
On steel sleeve 1, seal assembly 2 is connected to the both ends of stainless steel sleeve pipe 1, and elastic packing plate 6 is fixedly connected on wall 11 and stainless
The gap of 1 junction of steel sleeve, the actually wall bushing of stainless steel sleeve pipe 1, stainless steel sleeve pipe 1 and wall 11 uses elastic packing plate
6 are sealed, and 1 both ends of stainless steel sleeve pipe are sealed using seal assembly 2, and form confined air cavity.First material transfer pipe 4 and second
Material transfer pipe 5 is each passed through stainless steel sleeve pipe 1 and is connected on seal assembly 2, and the first material transfer pipe 4 and the second material transfer pipe 5 are across close
For sealing assembly 2 from wall one end to the other end, seal assembly 2, the first material transfer pipe 4 and the second material transfer pipe 5 are detachable accessory, can
It is assembled according to material delivery request, removable unloads washing and sterilizing down using rear.One end of air supply pipeline 7 and 1 phase of stainless steel sleeve pipe
Connection, the first diaphragm valve 9 are connected in air supply pipeline 7, and one end of pure steam pipeline 8 is connected with air supply pipeline 7, the second diaphragm
Valve 10 is connected on pure steam pipeline 8.What air supply pipeline 7 conveyed is the air of filtered cleaning, utilizes air supply pipeline 7 and the
The combination of one diaphragm valve 9 forms safety curtain.The air of filtered cleaning is sent with being higher than wall two side areas cleanliness and pressure
Enter stainless steel sleeve pipe 1, form the clean cavity of positive pressure, the other clean room air stream of wall hole two sides difference clean grade is isolated.In life
Production is cleared out a gathering place sterilisation stage, the biopharmaceutical liquids material transmitting isolating and protecting device and peripheral facility same period cleaning and sterilizing.It passes through
The different tube diameters of logical positive pressure cavity are connected with the first material transfer pipe 4 of quantity, the second material transfer pipe 5 with equipment such as peristaltic pump, Agitation Tanks,
Liquid material cleaning closed conveying channel is formed, the first material transfer pipe 4, the second material transfer pipe 5 can choose sterile fast interface.Stainless steel
The positive pressure cavity and elastic packing plate 6 of casing 1 ensure that clean environment.
The seal assembly 2 includes port cap and sealing plate.
According to the actual (real) thickness and material of wall 11, the type of process flow and material determines material pipeline wall-penetrating hole
The specification of size and the present apparatus, the diameter of the stainless steel sleeve pipe 1 are 100mm-150mm, meet transmission material requirement.
The wall thickness of the stainless steel sleeve pipe 1 is 4mm-10mm.Meet pressure and safety requirements.
The biopharmaceutical liquids material transmitting isolating and protecting device can be passed by detachable first material transfer pipe 4, second
Sterile, sealing transmitting, protection isolation are provided when 5 transfer liquid material of expects pipe is between the other region of different clean grades, detachably
Regulation washing and sterilizing is pressed in part, and online pure steam sterilizing can be achieved in non-collapsible part, and positive pressure pure air is blown into cavity, not only shape
At empty isolation barrier, air-flow protection can be also formed, constitutes dual fail-safe with the sealing element of device.
It is same that the biopharmaceutical liquids material transmitting isolating and protecting device can realize that single wall opening carries out more material transfer pipes
When convey different liquid materials, the cumbersome and labour for saving sterilizing and verifying and the container transfer of hard tube transfer system is negative
Lotus reduces pollution risk point, reduces pollution rate, reduces material loss and energy consumption, improves product quality and controlled level, and economy is received
It is beneficial good.
It is sterile closed defeated that the biopharmaceutical liquids material transmitting isolating and protecting device is exclusively used in bio-pharmaceuticals liquid material
It send and clean isolating device, changes traditional using container as the transfer mode of carrier, realize liquid material in different clean grades
The enclosed sterile transmitting of other production district, biological products having between contaminated area and Toxic Free Area.The biopharmaceutical liquids material passes
The application for passing isolating and protecting device greatly reduces container required for bio-pharmaceuticals liquid material conventional transmission, reduces the friendship of container
Fork pollution reduces the cleaning that container occupies, the space of sterilizing, storage, substantially reduces the labor intensity of operator, reduce energy consumption and
Enterprise operation cost, more effectively the control quality of production.
Detailed description of the invention
Fig. 1 is that the biopharmaceutical liquids material transmits isolating and protecting device structural schematic diagram.
Specific embodiment
Embodiment 1
The biopharmaceutical liquids material transmitting isolating and protecting device constitutes as follows: stainless steel sleeve pipe 1, seal assembly 2, pressure
Power table 3, the first material transfer pipe 4, the second material transfer pipe 5, elastic packing plate 6, air supply pipeline 7, pure steam pipeline 8, the first diaphragm valve 9,
Second diaphragm valve 10；Wherein, the stainless steel sleeve pipe 1 passes through wall 11 and is connected on wall 11, and pressure gauge 3 is connected to stainless
On steel sleeve 1, seal assembly 2 is connected to the both ends of stainless steel sleeve pipe 1, and elastic packing plate 6 is fixedly connected on wall 11 and stainless
The gap of 1 junction of steel sleeve, the actually wall bushing of stainless steel sleeve pipe 1, stainless steel sleeve pipe 1 and wall 11 uses elastic packing plate
6 are sealed, and 1 both ends of stainless steel sleeve pipe are sealed using seal assembly 2, and form confined air cavity.First material transfer pipe 4 and second
Material transfer pipe 5 is each passed through stainless steel sleeve pipe 1 and is connected on seal assembly 2, and the first material transfer pipe 4 and the second material transfer pipe 5 are across close
For sealing assembly 2 from wall one end to the other end, seal assembly 2, the first material transfer pipe 4 and the second material transfer pipe 5 are detachable accessory, can
It is assembled according to material delivery request, removable unloads washing and sterilizing down using rear.One end of air supply pipeline 7 and 1 phase of stainless steel sleeve pipe
Connection, the first diaphragm valve 9 are connected in air supply pipeline 7, and one end of pure steam pipeline 8 is connected with air supply pipeline 7, the second diaphragm
Valve 10 is connected on pure steam pipeline 8.What air supply pipeline 7 conveyed is the air of filtered cleaning, utilizes air supply pipeline 7 and the
The combination of one diaphragm valve 9 forms safety curtain.The air of filtered cleaning is sent with being higher than wall two side areas cleanliness and pressure
Enter stainless steel sleeve pipe 1, form the clean cavity of positive pressure, the other clean room air stream of wall hole two sides difference clean grade is isolated.In life
Production is cleared out a gathering place sterilisation stage, the biopharmaceutical liquids material transmitting isolating and protecting device and peripheral facility same period cleaning and sterilizing.It passes through
The different tube diameters of logical positive pressure cavity are connected with the first material transfer pipe 4 of quantity, the second material transfer pipe 5 with equipment such as peristaltic pump, Agitation Tanks,
Liquid material cleaning closed conveying channel is formed, the first material transfer pipe 4, the second material transfer pipe 5 can choose sterile fast interface.Stainless steel
The positive pressure cavity and elastic packing plate 6 of casing 1 ensure that clean environment.
The seal assembly 2 includes port cap and sealing plate.
According to the actual (real) thickness and material of wall 11, the type of process flow and material determines material pipeline wall-penetrating hole
The specification of size and the present apparatus, the diameter of the stainless steel sleeve pipe 1 are 100mm-150mm, meet transmission material requirement.
The wall thickness of the stainless steel sleeve pipe 1 is 4mm-10mm.Meet pressure and safety requirements.
The biopharmaceutical liquids material transmitting isolating and protecting device can be passed by detachable first material transfer pipe 4, second
Sterile, sealing transmitting, protection isolation are provided when 5 transfer liquid material of expects pipe is between the other region of different clean grades, detachably
Regulation washing and sterilizing is pressed in part, and online pure steam sterilizing can be achieved in non-collapsible part, and positive pressure pure air is blown into cavity, not only shape
At empty isolation barrier, air-flow protection can be also formed, constitutes dual fail-safe with the sealing element of device.
It is same that the biopharmaceutical liquids material transmitting isolating and protecting device can realize that single wall opening carries out more material transfer pipes
When convey different liquid materials, the cumbersome and labour for saving sterilizing and verifying and the container transfer of hard tube transfer system is negative
Lotus reduces pollution risk point, reduces pollution rate, reduces material loss and energy consumption, improves product quality and controlled level, and economy is received
It is beneficial good.
It is sterile closed defeated that the biopharmaceutical liquids material transmitting isolating and protecting device is exclusively used in bio-pharmaceuticals liquid material
It send and clean isolating device, changes traditional using container as the transfer mode of carrier, realize liquid material in different clean grades
The enclosed sterile transmitting of other production district, biological products having between contaminated area and Toxic Free Area.The biopharmaceutical liquids material passes
The application for passing isolating and protecting device greatly reduces container required for bio-pharmaceuticals liquid material conventional transmission, reduces the friendship of container
Fork pollution reduces the cleaning that container occupies, the space of sterilizing, storage, substantially reduces the labor intensity of operator, reduce energy consumption and
Enterprise operation cost, more effectively the control quality of production.
Certain pharmaceutical factory production of vaccine workshop will come from D grades using biopharmaceutical liquids material transmitting isolating and protecting device
The liquid materials such as physiological saline, the culture solution of clean area liquid mixing system are sent to the sterile room of C+B grades of clean areas, carry out thin
The nutrient solution addition of born of the same parents' incubation, Virus culture process wash.
The application of biopharmaceutical liquids material transmitting isolating and protecting device reduces a large amount of transferring case, and every
From air-lock, reduce the setting of sterilizer, reduce that container is temporary, cleaning area, reduces construction investment, reduce cleaning, sterilizing
The personnel in post prepare, and reduce energy consumption and operating cost, improve production efficiency, effectively increase the anti-pollution level of system, drop
Low systemic contamination risk passes through industry GMP certification.With more huge economic value and social value.
Claims (4)
1. a kind of biopharmaceutical liquids material transmits isolating and protecting device, it is characterised in that: the biopharmaceutical liquids material passes
It is as follows to pass isolating and protecting device composition: stainless steel sleeve pipe (1), seal assembly (2), pressure gauge (3), the first material transfer pipe (4), second
Material transfer pipe (5), elastic packing plate (6), air supply pipeline (7), pure steam pipeline (8), the first diaphragm valve (9) and the second diaphragm valve
(10)；Wherein, the stainless steel sleeve pipe (1) passes through wall (11) and is connected on wall (11), and pressure gauge (3) is connected to stainless
On steel sleeve (1), seal assembly (2) is connected to the both ends of stainless steel sleeve pipe (1), and elastic packing plate (6) is fixedly connected on wall
(11) and stainless steel sleeve pipe (1) junction, the first material transfer pipe (4) and the second material transfer pipe (5) are each passed through stainless steel sleeve pipe (1) simultaneously
It is connected on seal assembly (2), one end of air supply pipeline (7) is connected with stainless steel sleeve pipe (1), the first diaphragm valve (9) connection
On air supply pipeline (7), one end of pure steam pipeline (8) is connected with air supply pipeline (7), and the second diaphragm valve (10) is connected to pure
On steam pipework (8).
2. transmitting isolating and protecting device according to biopharmaceutical liquids material described in claim 1, it is characterised in that: the sealing group
Part (2) includes port cap and sealing plate.
3. transmitting isolating and protecting device according to biopharmaceutical liquids material described in claim 2, it is characterised in that: the stainless steel
The diameter of casing (1) is 100mm-150mm.
4. transmitting isolating and protecting device according to claims 1 or 2 or the 3 biopharmaceutical liquids materials, it is characterised in that: described
The wall thickness of stainless steel sleeve pipe (1) is 4mm-10mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820822955.9U CN208395171U (en) | 2018-05-30 | 2018-05-30 | A kind of biopharmaceutical liquids material transmitting isolating and protecting device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820822955.9U CN208395171U (en) | 2018-05-30 | 2018-05-30 | A kind of biopharmaceutical liquids material transmitting isolating and protecting device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208395171U true CN208395171U (en) | 2019-01-18 |
Family
ID=65134460
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820822955.9U Active CN208395171U (en) | 2018-05-30 | 2018-05-30 | A kind of biopharmaceutical liquids material transmitting isolating and protecting device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208395171U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109914987A (en) * | 2019-02-22 | 2019-06-21 | 荣昌生物制药（烟台）有限公司 | A kind of transmitting window assembly |
| CN112209109A (en) * | 2020-10-30 | 2021-01-12 | 重庆智翔金泰生物制药有限公司 | Isolated material conveying method |
-
2018
- 2018-05-30 CN CN201820822955.9U patent/CN208395171U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109914987A (en) * | 2019-02-22 | 2019-06-21 | 荣昌生物制药（烟台）有限公司 | A kind of transmitting window assembly |
| CN109914987B (en) * | 2019-02-22 | 2023-06-13 | 荣昌生物制药(烟台)股份有限公司 | Pass-through box subassembly |
| CN112209109A (en) * | 2020-10-30 | 2021-01-12 | 重庆智翔金泰生物制药有限公司 | Isolated material conveying method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2006254378B2 (en) | Fermenter system for biotechnical processes | |
| CN208395171U (en) | A kind of biopharmaceutical liquids material transmitting isolating and protecting device | |
| CN102220242B (en) | Culture solution continuous filling method and system for chlamydomonas culture | |
| CN203999609U (en) | Anerobe dialysis culturing device | |
| CN101579678A (en) | Method for cleaning and disinfecting process system of liquid preparation for biological product | |
| CN203048949U (en) | Cell culture bag | |
| CN215048560U (en) | Aseptic liquid system of joining in marriage suitable for suspension | |
| CN109364279A (en) | It is a kind of can online CIP/SIP thimerosal filtration sterilization and cleaning system | |
| CN209144154U (en) | A kind of sterile controlled amounts type classification inoculation apparatus of seeding tank | |
| CN211688986U (en) | Preparation facilities of bacillus subtilis zymotic fluid suspension | |
| CN209569542U (en) | A kind of fuid distribution system | |
| CN209253673U (en) | A kind of sterile switching device of biological products liquid mixing system | |
| CN204582106U (en) | A kind of transfusion bag device of peritoneal dialysis solution | |
| CN208869602U (en) | A kind of bioreactor perfusion culture plumbing connection system | |
| CN206799622U (en) | A kind of fermentation tank sterile sampling and sample reception system | |
| CN205861441U (en) | Pharmaceutical sterile test enrichment parallel-type filter | |
| CN106811393B (en) | A kind of fermentor feed supplement jack apparatus | |
| CN205472875U (en) | That is applied to pipeline formula ozone disinfection device adds pencil way | |
| CN208594290U (en) | A kind of device for the preparation of actinospore suspension | |
| CN205839033U (en) | A kind of stainless steel reactor dual pathways mends sugar pipeline | |
| CN213570414U (en) | Fermentation and seed transfer distribution station | |
| CN217202706U (en) | Safe convenient fermentation cylinder feed supplement device | |
| CN212900310U (en) | Sanitary-grade integrated quick-connection device and sterilizer | |
| CN205839004U (en) | A kind of disposable bioreactor feeding pipe | |
| CN203229538U (en) | Feeding, split-charging and collecting device for spinner bottle cultivation of cells |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |