CN208297542U - POCT Full-automatic chemiluminescence immunoassay analysis meter - Google Patents
POCT Full-automatic chemiluminescence immunoassay analysis meter Download PDFInfo
- Publication number
- CN208297542U CN208297542U CN201820859982.3U CN201820859982U CN208297542U CN 208297542 U CN208297542 U CN 208297542U CN 201820859982 U CN201820859982 U CN 201820859982U CN 208297542 U CN208297542 U CN 208297542U
- Authority
- CN
- China
- Prior art keywords
- reaction
- sample
- reagent
- cup
- automatic chemiluminescence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The utility model discloses a kind of POCT Full-automatic chemiluminescence immunoassay analysis meter, including rack, reaction mechanism, wiper mechanism and the reagent sample mechanism being oppositely arranged with the reaction mechanism, the reaction mechanism and reagent sample mechanism are all set in the rack, the reaction mechanism is hollow structure, the wiper mechanism is set in the hollow structure of the reaction mechanism, the reaction cup for cleaning in the reaction mechanism.Wiper mechanism is arranged in reaction tray by the way that reaction tray is set as hollow structure for technical solutions of the utility model.Cleaning operation can be completed in reaction mechanism to realize, to achieve the purpose that reduce equipment volume, meet current clinical trial demand.Reaction cup is transmitted in optical de-tection means again after cleaning and is detected.
Description
Technical field
The utility model relates to biochemical fields, in particular to POCT Full-automatic chemiluminescence immunoassay analysis meter.
Background technique
As people are for the pay attention to day by day of health, clinical testing techniques also enter the epoch of a high speed development, and
The important a member of Chemiluminescence Apparatus as clinical examination mechanism, substantially belongs to standard configuration now.On the one hand due to its test item
Diversity, inspection, the screening of various diseases, while the accurately measurement attribute of Chemiluminescence Apparatus can be competent at, clinic can be examined
It is disconnected to provide accurate judgment basis.
POCT Full-automatic chemiluminescence immunoassay analysis meter in the prior art, generally bulky, flexibility is low, for one
A little limited departments in space, are unable to satisfy its use demand, have severely impacted the timeliness of test, it is possible to generate to clinic
Some negative impacts.
Utility model content
The main purpose of the utility model is to propose a kind of POCT Full-automatic chemiluminescence immunoassay analysis meter, it is intended to be solved existing
Have in technology that POCT Full-automatic chemiluminescence immunoassay analysis meter is bulky, flexibility is low, the slow problem of test speed.
To achieve the above object, the utility model proposes POCT Full-automatic chemiluminescence immunoassay analysis meter, comprising: machine
Frame, reaction mechanism, wiper mechanism and the reagent sample mechanism being oppositely arranged with the reaction mechanism, the reaction mechanism with it is described
Reagent sample mechanism is all set in the rack, and the reaction mechanism is hollow structure, and the wiper mechanism is set to described
Reaction cup in the hollow structure of reaction mechanism, for cleaning in the reaction mechanism.
Preferably, the reaction mechanism include for placing response cup reaction tray, connect with the reaction tray first
Actuator, the reaction tray are rotatably dispose in the rack, and first actuator drives the reaction tray rotation so that institute
It states reaction cup and turns to corresponding sample-adding position.
Preferably, the reaction mechanism further includes mixing part for mixing the first of reaction cup, and the reaction tray is equipped with
Opening, the first mixing part is arranged at the opening, when the reaction cup is turned to the opening by the reaction tray
Abut the reaction cup with the first mixing part.
Preferably, the wiper mechanism include lifters, third actuator, the rotating disc for placing the reaction cup,
For injecting the outlet pipe of cleaning agent and for the drainpipe of draining, the rotating disc is set to the hollow structure of the reaction tray
In, the third actuator drives the turn disc so that the reaction cup turns to cleaning position, the outlet pipe and institute
It states drainpipe to be set to above the cleaning position, and connects the lifters, the rotating disc is hollow structure, the lifters
It is set in the hollow structure of the rotating disc, the lifters protrude into the outlet pipe and the drainpipe when falling described
In reaction cup, and the drainpipe and the bottom wall of the reaction cup abut against.
Preferably, the wiper mechanism further includes magnetic absorption member, the magnetic absorption member be set to the corresponding outlet pipe with it is described
On rotating disc below drainpipe.
Preferably, the wiper mechanism further includes the second mixing part, and the second mixing part is set on the rotating disc,
The reaction cup is turned to and is abutted with the second mixing part by the rotating disc.
Preferably, reagent sample mechanism includes reagent sample disk and the second driving connecting with the reagent sample disk
Part, the reagent sample disk are rotatably dispose in the rack, second actuator drive the reagent sample disk rotation with
The Reagent Tube and the sample tube is set to turn to sampling position.
Preferably, reagent sample mechanism further includes shell, and the reagent sample disk is set in the shell, described
Reagent Tube is equipped at least two mutually independent accommodating cavities, and the inner walls are equipped with internal tooth, on the outermost side described
Accommodating cavity bottom is equipped with gear, and the gear and the interior tooth engagement are located at outermost to drive when the reagent sample disk rotates
The accommodating cavity rotation.
Preferably, the POCT Full-automatic chemiluminescence immunoassay analysis meter further includes sampling mechanism, described to use mechanism packet
Include pedestal and sampling needle, the sampling needle and the removable connection of the pedestal, when the sampling needle is moved along the pedestal by
The sampling position is moved to the sample-adding position, and the reagent in the sample and the Reagent Tube in the sample tube is added with magnetic bead
Enter into the reaction cup.
Preferably, the sampling mechanism further includes the cleaning component for cleaning the sampling needle, and the cleaning component is set
It is placed on the motion track of the sampling needle.
Wiper mechanism setting is being reacted machine by the way that reaction mechanism is set as hollow structure by technical solutions of the utility model
In the hollow structure of structure.Sampling mechanism be moved to sampling position, while reagent sample mechanism by reagent sample disk Reagent Tube with
Sample tube turns at position corresponding with the sampling position, and sampling mechanism is extend into Reagent Tube and sample tube from the sampling position inhales
Sampling sheet, reagent and magnetic bead；At this point, reaction tray turns to empty reaction cup at position corresponding with sample-adding position, sampling mechanism
It is moved to sample-adding position from the sampling position, and sample, reagent are put into the reaction cup of the sky with magnetic bead and reacted.Reaction
Reaction cup is transferred on wiper mechanism afterwards, which is rotatably set in the hollow structure of the reaction tray, this is clear
Washing machine structure includes multiple groups outlet pipe and drainpipe for repeatedly cleaning to the magnetic bead in reaction cup, is realized by rotating disc anti-
Transmitting of the cup between multiple groups outlet pipe and drainpipe is answered, cleaning operation can be completed in reaction mechanism to realize, thus
Achieve the purpose that reduce equipment volume, meets current clinical trial demand.Reaction cup is transmitted to optical detection again after cleaning
It is detected in mechanism.
Detailed description of the invention
In order to illustrate the embodiment of the utility model or the technical proposal in the existing technology more clearly, below will be to embodiment
Or attached drawing needed to be used in the description of the prior art is briefly described, it should be apparent that, the accompanying drawings in the following description is only
It is some embodiments of the utility model, for those of ordinary skill in the art, in the premise not made the creative labor
Under, the structure that can also be shown according to these attached drawings obtains other attached drawings.
Fig. 1 is the concrete structure schematic diagram of the utility model POCT Full-automatic chemiluminescence immunoassay analysis meter；
Fig. 2 is the concrete structure schematic diagram of the utility model reaction mechanism；
Fig. 3 is the concrete structure schematic diagram of the utility model wiper mechanism；
Fig. 4 is the enlarged structure schematic diagram in Fig. 3 at A；
Fig. 5 is the concrete structure schematic diagram of the utility model reagent sample mechanism；
Fig. 6 is the concrete structure schematic diagram of the utility model sampling mechanism；
Fig. 7 is the concrete structure schematic diagram of the utility model grasping mechanism；
Fig. 8 is the concrete structure schematic diagram of the utility model recovering mechanism；
Fig. 9 is the utility model external structure schematic diagram.
Drawing reference numeral explanation:
The embodiments will be further described with reference to the accompanying drawings for the realization, functional characteristics and advantage of the utility model aim.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describing, it is clear that described embodiment is only a part of the embodiment of the utility model, rather than all
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are not making creative work premise
Under every other embodiment obtained, fall within the protection scope of the utility model.
It is to be appreciated that if related in the utility model embodiment directionality instruction (such as upper and lower, left and right, it is preceding,
Afterwards ...), then directionality instruction is only used for explaining opposite between each component under a certain particular pose (as shown in the picture)
Positional relationship, motion conditions etc., if the particular pose changes, directionality instruction is also correspondingly changed correspondingly.
In addition, if relating to the description of " first ", " second " etc. in the utility model embodiment, " first ", " the
Two " etc. description is used for description purposes only, and is not understood to indicate or imply its relative importance or is implicitly indicated meaning
The quantity of the technical characteristic shown." first " is defined as a result, the feature of " second " can explicitly or implicitly include at least one
A this feature.It in addition, the technical solution between each embodiment can be combined with each other, but must be with ordinary skill
Based on personnel can be realized, this technical side will be understood that when the combination of technical solution appearance is conflicting or cannot achieve
The combination of case is not present, also not within the protection scope of the requires of the utility model.
The utility model proposes a kind of POCT Full-automatic chemiluminescence immunoassay analysis meters, please refer to Fig. 1, and the POCT is complete certainly
Dynamic chemical illumination immunity analysis instrument includes:
Reaction mechanism 20, reaction mechanism 20 are mainly used for providing a reacting environment, but sample and examination for sample and reagent
Agent needs certain temperature that can react, and in practice, temperature is usually 37 degree or so.It therefore can be in reaction machine
The bottom setting heating component of structure 20 improves temperature to react for sample with reagent to be internally heated to reaction mechanism 20
Condition.At the same time it can also stick heat-preservation cotton outside reaction mechanism 20 to improve the stability of 20 internal temperature of reaction mechanism.Into
One step, real-time monitoring can also be carried out to the temperature inside reaction mechanism 20 using temperature sensor, when in reaction mechanism 20
When the temperature in portion is lower than preset value, then heating component is automatically opened, when the temperature inside reaction mechanism 20 is higher than preset value, then
Heating component is automatically shut down, is recycled by concussion, to be to reach metastable preset temperature inside reaction mechanism 20；
Wiper mechanism 30, wiper mechanism 30 are mainly used for carrying out Beads enrichment to 22 solution of reaction cup after reaction.It is described
Wiper mechanism 30 is set in the hollow body of the reaction mechanism 20, respective relatively independent rotation, non-interference, to reach
To the mesh for reducing equipment volume from plane space；
Reagent sample mechanism 40, reagent sample mechanism 40 is mainly used for storing Reagent Tube 42 and sample tube 43, in practical fortune
In, in order to guarantee that the reagent in reagent sample mechanism 40 is not contaminated with sample, reagent sample mechanism 40 is usually made to be in base
The state of this sealing, and in external paste heat-preserving cotton to guarantee that the temperature inside reagent sample mechanism 40 is relatively stable in one
State.It further, can also be by reducing temperature to reduce the activity of sample and reagent, so that it is contaminated general to reduce its
Cooling assembly can also be arranged in the bottom of reagent sample mechanism 40 in rate, which includes but is not limited to semiconductor refrigerating
Piece.The one side of semiconductor chilling plate refrigeration is close to 40 bottom of reagent sample mechanism, to reduce inside reagent sample mechanism 40
Temperature, and generate heat one side connect with cooling fin by heat-conducting cream, heat dissipation is implemented by air-cooled mode, in time system
Cold generated heat dissipation is to device external.Further, reagent sample machine can also be monitored at any time using temperature control system
Temperature inside structure 40, so that the temperature in the reagent sample mechanism 40 be made to be controlled effectively.When detecting reagent sample
When 40 internal temperature of mechanism is higher than preset value, then temperature control system, which automatically opens cooling piece power supply, makes work, until temperature is reduced to
After range in preset value, cooling piece stops working.To achieve the purpose that control 40 internal temperature of reagent sample mechanism；
Rack 10 is mainly used for supporting all parts on POCT Full-automatic chemiluminescence immunoassay analysis meter；The reagent sample
Mechanism 40 and the reaction mechanism 20 are oppositely arranged in the rack 10, and the reaction mechanism 20 is hollow structure, described
Wiper mechanism 30 is set in the hollow structure of the reaction mechanism 20, the reaction cup for cleaning in the reaction mechanism 20
22。
Specifically, the POCT Full-automatic chemiluminescence immunoassay analysis meter further includes grasping mechanism 70, the grasping mechanism
70 be set in the rack 10 with by the crawl of reaction cup 22 on the reaction mechanism 20 on the wiper mechanism 30 or will
In the crawl to the optical de-tection means 60 of reaction cup 22 after reaction.Grasping mechanism 70 is mainly used for crawl and transfer reaction cup
22.The grasping mechanism 70 can vertical up-or-down movement, which declines to grab reaction cup 22, and reaction cup 22 is mentioned
It rises；The grasping mechanism 70 can be moved left and right laterally to be driven the reaction cup 22 between all parts；Step can be passed through among the above
It into motor but is not limited to stepper motor and realizes that grasping mechanism 70 perpendicularly or transversely moves, utilize guidance set positioning transmission side
Initial bit is defined to, position sensor.The grasping mechanism 70 further include for by reaction cup clamp folder cup assembly,
The movement mechanism is controlled by rotating stepper motor, and under natural conditions, two intermediate plates are separated to both sides under the action of the spring, when need
When clamping, motor drives two intermediate plates to move inward, compressed spring, while two panels clip forms cup outer wall and squeezes,
In the case where certain pressure, the frictional force support clip cup assembly between clip and cup picks up reaction cup and is transferred to target position
It sets, reaction cup falls in target position after motor rotation is unclamped, and folder cup assembly leaves, and so far reaction cup transfer action is completed.
Specifically, the POCT Full-automatic chemiluminescence immunoassay analysis meter further includes optical de-tection means 60 and recovering mechanism
80, the recovering mechanism 80 includes upper cup position 81, check bit 82, waste discharge liquid level 83, loses cup position 84 and for placing response cup
Recovering tray, the recovering tray receive reaction cup 22 to be detected, the optical de-tection means 60 when turning to the upper cup position 81
Be set to makes the reaction cup 22 described with 82 corresponding position of check bit, the recovering tray when turning to the check bit 82
Optical de-tection means 60 detect, and the recovering tray makes 22 drain of reaction cup when turning to the waste discharge liquid level 83, and described time
Closing quotation, which turns to described lose, to be lost the reaction cup 22 to recycle out when position 84.In practice, because light can be to optics
The measuring accuracy of testing agency 60 generates certain influence, it is therefore desirable to which optical de-tection means 60 and recovering mechanism are arranged in rack
Inside 10, detected with being guaranteed at dark space.Optical de-tection means 60 are mainly used for acquiring optical signalling, simultaneously to reaction
Luminous substrate is added in reaction cup after the completion of cleaning, reaction cup 22 is moved to by the upper of recovering mechanism 80 by grasping mechanism 70
To prepare to detect at cup position 81, recovering tray rotates so that reaction cup 22 turns to check bit 82 from upper cup position 81 is detected, and examines
Recovering tray is rotated again so that reaction cup 22 turns to waste discharge liquid level 83 from check bit 82, by the waste liquid pumping in cup after survey
From recovering tray is rotated again so that reaction cup 22 is turned to from waste discharge liquid level 83 loses cup position 84 after removal waste fluid, and by cup
It is lost out from window.Recovering tray rotates back into the waiting of cup position 81 again and scoops out next reaction cup 22, so recycles.
Wiper mechanism 30 is arranged anti-by the way that reaction mechanism 20 is set as hollow structure for technical solutions of the utility model
In the hollow structure for answering mechanism 20.Sample in candidate agent sample mechanism 40 is added in reaction cup 22 with reagent to react.Reaction
Reaction cup 22 is crawled mechanism 70 and is transferred on wiper mechanism 30 afterwards, which is rotatably set to the reaction mechanism
In 20 hollow structure, cleaning operation can be completed in reaction mechanism 20 to realize, reduce equipment volume to reach
Purpose meets current clinical trial demand.Reaction cup 22 is transmitted in optical de-tection means 60 again after cleaning and is detected.
Specifically, the reaction mechanism 20 includes connecting for the reaction tray 21 of placing response cup 22, with the reaction tray 21
The first actuator connect, the reaction tray 21 are rotatably dispose in the rack 10, and first actuator drives the reaction
Disk 21 rotates so that the reaction cup 22 turns to corresponding sample-adding position 23.It is equipped in reaction tray 21 several described for placing
The accommodation groove of reaction cup 22, the accommodation groove are distributed on the inner ring and outer ring of reaction tray 21, are arranged side by side to increase reaction
The carrying quantity of cup 22, can accommodate more reaction cups and be reacted, to improve the detection efficiency of equipment.It can manage
Solution, reaction tray 21 can be by way of stepper motors and synchronous belt cooperation, so that reaction tray 21 rotates, to guarantee each reaction
On the sample-adding rail position that cup can be run to.Code-disc stroke low and high level after sensor is arranged on the outside of reaction tray 21 to become
Change, so as to position each reaction cup 22 by the distance of sample-adding position 23, so that reaction cup 22 be enable to rest on sample-adding position
It sentences and is loaded.
Specifically, the wiper mechanism 30 includes lifters 32, third actuator, for placing turning for the reaction cup 22
Moving plate 31, the outlet pipe 33 for injecting cleaning agent and the drainpipe 34 for draining, the rotating disc 31 are set to described anti-
It should coil in 21 hollow structure, the third actuator drives the rotation of rotating disc 31 so that the reaction cup 22 turns to clearly
Position is washed, the outlet pipe 33 is set to above the cleaning position with the drainpipe 34, and connects the lifters 32, and described turn
Moving plate 31 is hollow structure, and the lifters 32 are set in the hollow structure of the rotating disc 31, and the lifters 32 are fallen
When protrude into the outlet pipe 33 in the reaction cup 22 with 34 pipes of the draining, and the drainpipe 34 and the reaction cup 22
Bottom wall abut against.Be again provided with multiple accommodation grooves for placing response cup 22 on rotating disc 31, the rotation of rotating disc 31 with
Reaction cup 22 is set to turn to the lower section of outlet pipe 33 Yu drainpipe 34, lifters 32 and rotating disc 31 are relatively independent, therefore are turning
When Moving plate 31 rotates, lifters 32 will not be with turn disc, i.e. outlet pipe 33 and the relative rotation disk 31 of drainpipe 34 is static,
To make each reaction cup 22 can be by being cleaned below outlet pipe 33 and drainpipe 34.Lifters 32 decline to use
Water pipe 33 and drainpipe 34 are extend into reaction cup, and cleaning agent is added into reaction cup 22 and is cleaned for outlet pipe 33, drainpipe
34 opposite outlet pipes 33 are longer, because the waste liquid after drainpipe 34 needs to clean all is sucked out, drainpipe 34 needs
It is abutted with 22 bottom of reaction cup to guarantee that waste liquid is all sucked out, while 34 bottom of drain pipe is equipped with notch, to prevent nozzle from being supported
Dead blocking.It is appreciated that wiper mechanism 30 may include multiple groups outlet pipe 33 and drainpipe 34, to carry out repeatedly to reaction cup 22
Cleaning is to guarantee to clean up.
Specifically, the wiper mechanism 30 further includes magnetic absorption member, the magnetic absorption member be set to the corresponding outlet pipe 33 with
On the rotating disc 31 of 34 lower section of drainpipe.Because containing in practice in reaction, there are many magnetic beads, by setting on rotating disc 31
The magnetic absorption member for setting a certain strength, to guarantee that magnetic bead can effectively be stayed in reaction cup 22 in drain, and it is other useless
Liquid is then discharged.
Specifically, reagent sample mechanism 40 include reagent sample disk 41 and connect with the reagent sample disk second
Actuator, the reagent sample disk 41 are rotatably dispose in the rack 10, and second actuator drives the reagent sample
Disk 41 rotates so that the Reagent Tube 42 and the sample tube 43 turn to sampling position 44.Reagent Tube 42 on reagent sample disk 41
Put by the way of circumference array, in the placement location that the gap location of Reagent Tube 42 is sample tube 43, each Reagent Tube 42 with
One sample tube 43 is corresponding, so that sampling mechanism once can be sampled all, without repeatedly being cleaned, improves efficiency.
Specifically, the POCT Full-automatic chemiluminescence immunoassay analysis meter further includes sampling mechanism 50, the sampling mechanism
50 include pedestal and sampling needle 51, and the sampling needle 51 moves connection with the pedestal, and the sampling needle 51 is along the bottom
The sample-adding position 23 is moved to by the sampling position 44 when seat is mobile, by the sample and the Reagent Tube in the sample tube 43
Reagent and magnetic bead in 42 are added in the reaction cup 22.The sampling needle 51 has liquid level detection function, when the sampling needle
51 during the decline, and when needle point touches liquid level, the capacitance of the sampling needle can then change, and then give on circuit
Signal is judged out, judges that signal judges that sampling needle 51 reaches liquid level according to this, is done further according to actual needs next other dynamic
Make timing.
Further, the sampling needle 51 has collision prevention function, and the top of sampling needle 51 is provided with anticollision mechanism.This is anti-
The structure that collides includes the elastic component that 51 top of sampling needle is arranged in, and is pushed down sampling needle 51 by elastic component under normal condition, when
Sampling needle 51 occurs in the case where bottoming out or colliding, and sampling needle 51 offsets collision by squeezing the elastic component, meanwhile, the anticollision
Mechanism further includes the optocoupler and light barrier that 51 upper end of sampling needle is arranged in, when sampling needle 51 squeezes elastic component, the light barrier
It is detached from optocoupler, so that optocoupler changes circuit signal, continues to decline to control and stop sampling needle 51, prevents fragility
Sampling needle 51 is damaged, it is often more important that, when there is difficult to handle phenomenon, sampling needle 51 also can timely stop motion, with
Anti- further injury causes.
As one embodiment, detection process are as follows: sampling mechanism 50 is moved to sampling position 44, while reagent sample mechanism
40 by reagent sample disk 41 Reagent Tube 42 and sample tube 43 turn at position corresponding with the sampling position 44, sampling mechanism
50 extend into absorption sample, reagent and magnetic bead in Reagent Tube 42 and sample tube 43 from the sampling position 44；At this point, reaction tray 21 will be empty
Reaction cup 22 turn to at the corresponding position in sample-adding position 23, sampling mechanism 50 is moved to from the sampling position 44 and is loaded position
23, and sample, reagent are put into the reaction cup 22 of the sky with magnetic bead and reacted.It will reaction by the first mixing mechanism 24
Reagent and sample in cup mix, and wait for sample and reagent after the completion of mixing quietly at 37 ° and carry out in the reaction tray 21 of opposing seal
Incubation reaction.Reaction cup 22 is crawled mechanism 70 and is transferred on wiper mechanism 30 after reaction, which is rotatably arranged
In the hollow structure of the reaction tray 21, which includes multiple groups outlet pipe 33 and drainpipe 34 for repeatedly to anti-
The magnetic bead in cup 22 is answered to be cleaned, magnetic bead passes through the magnetic absorption member being arranged on rotating disc 31 and is tightly adsorbed on wall of cup, thus
Reaction cup 22 will not be discharged by drainpipe 34, by rotating disc 31 realize reaction cup 22 multiple groups outlet pipe 33 and drainpipe 34 it
Between transmitting, thus realize cleaning operation can be completed in reaction mechanism 20, thus achieve the purpose that reduce equipment volume, symbol
Close current clinical trial demand.Reaction cup 22 is transmitted in reaction tray 21 again by grasping mechanism 70 after cleaning, passes through sampling
Needle 51 is added in reaction cup 22 from taking out quantitative substrate solution in substrate bottle, and mixes part 24 by first and mix, then by
Grasping mechanism 70 grabs cup position 81, is detected by optical de-tection means 60.The acquisition reaction of optical de-tection means 60
Photooptical data in cup 22, that is, target substance and substrate solution occur to chemically react generated photon numbers-light intensity, lead to
The light intensity measured is crossed, specific calculation formula is re-incorporated into, the concentration value of the measurement object can be conversed.Pass through recycling machine later
Structure 80 recycles reaction cup 22.
Specifically, the reaction mechanism 20 further includes mixing part 24, the reaction tray for mixing the first of reaction cup 22
21 are equipped with opening, and the first mixing part 24 is arranged at the opening, and the reaction tray 21 rotates the reaction cup 22
Make the reaction cup 22 mix part 24 with described first when to the opening to abut.The opening makes the reaction by the position
Outside cup 22 is partially exposed at, when reaction tray 21 rotates, the reaction cup 22 for turning to the position is then abutted with the first mixing part 24, the
One, which mixes part 24, shakes, and reacts so that the sample in reaction cup 22, reagent be made to mix well with magnetic bead.It is appreciated that reaction tray
21 respectively have one first mixing part 24 in inner ring, outer ring sample-adding position, to guarantee the sample in reaction cup 22 all in reaction tray 21
Originally, reagent is mixed well with magnetic bead and is reacted.
Specifically, the wiper mechanism 30 further includes the second mixing part 35, the second mixing part 35 is set to described turn
On Moving plate 31, the reaction cup 22 is turned to and is abutted with the second mixing part 35 by the rotating disc 31.It is mixed by second
Part 35 mixes magnetic bead, reduce because agglomeration, dead angle and caused by the halfway problem of cleaning.
Specifically, reagent sample mechanism 40 further includes shell, the reagent sample disk 41 is set in the shell,
The Reagent Tube 42 is equipped at least two mutually independent accommodating cavities, and the inner walls are equipped with internal tooth, is located at outermost
The accommodating cavity bottom be equipped with gear, the gear and the interior tooth engagement are when the reagent sample disk 41 rotates to drive position
It is rotated in the outermost accommodating cavity.In practice, reagent type required for different types of detection is different, usually
It is set on each Reagent Tube 42 there are four independent cavity, is needed that more or less independent chambers can also be arranged according to detection
Body.The cavity stores reagent components different corresponding to each detection project respectively, wherein outermost cavity is for loading
Magnetic bead is in cylindrical body, and bottom belt has gear, is meshed by gear with shell internal gear, should when reagent sample disk 41 rotates
Cavity can rotate relatively freely, to mix to the magnetic bead solution in reagent bottle, to prevent magnetic bead from settling.
Specifically, the sampling mechanism 50 further includes the cleaning component 52 for cleaning the sampling needle, the cleaning part
Part is set on the motion track of the sampling needle 51.When sampling needle 51 by reagent, sample and magnetic bead be put into reaction cup 22 it
Afterwards, it is moved at cleaning 52 position of component and is cleaned, to sample and reagent when preventing sampling needle 51 from being acquired next time
Etc. polluting.
Specifically, the sampling needle 51 is variable diameter needle tubing, to guarantee that the volume in needle is beaten enough, make the sample of quantitative absorption
This or reagent do not exceed needle tubing and enter to be difficult to clean thoroughly in pipeline or connector, and then avoid the occurrence of cross contamination.
The above is only the preferred embodiment of the present invention, and therefore it does not limit the scope of the patent of the utility model,
Under all utility models in the utility model are conceived, equivalent structure made based on the specification and figures of the utility model
Transformation, or directly/be used in other related technical areas indirectly and be included in the scope of patent protection of the utility model.
Claims (10)
1. a kind of POCT Full-automatic chemiluminescence immunoassay analysis meter, which is characterized in that the POCT Full-automatic chemiluminescence is immune
Analyzer includes: rack, reaction mechanism, wiper mechanism and the reagent sample mechanism being oppositely arranged with the reaction mechanism, described
Reaction mechanism and reagent sample mechanism are all set in the rack, and the reaction mechanism is hollow structure, the cleaning
Mechanism is set in the hollow structure of the reaction mechanism, the reaction cup for cleaning in the reaction mechanism.
2. POCT Full-automatic chemiluminescence immunoassay analysis meter as described in claim 1, which is characterized in that the reaction mechanism packet
The first actuator for including the reaction tray for placing response cup, connecting with the reaction tray, the reaction tray are rotatably dispose in institute
It states in rack, first actuator drives the reaction tray rotation so that the reaction cup turns to corresponding sample-adding position.
3. POCT Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 2, which is characterized in that the reaction mechanism is also
Part is mixed including first for mixing reaction cup, the reaction tray is equipped with opening, and the first mixing part is set to described
Opening, the reaction tray support the reaction cup with the first mixing part
It connects.
4. POCT Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 2, which is characterized in that the wiper mechanism packet
Include lifters, third actuator, the rotating disc for placing the reaction cup, the outlet pipe for injecting cleaning agent and for arranging
The drainpipe of water, the rotating disc are set in the hollow structure of the reaction tray, and the third actuator drives the rotation
Disk rotates so that the reaction cup turns to cleaning position, and the outlet pipe and the drainpipe are set to above the cleaning position,
And the lifters are connected, the rotating disc is hollow structure, and the lifters are set in the hollow structure of the rotating disc,
The lifters make the outlet pipe when falling and the drainpipe protrudes into the reaction cup, and the drainpipe and described anti-
The bottom wall of cup is answered to abut against.
5. POCT Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 4, which is characterized in that the wiper mechanism is also
Including magnetic absorption member, the magnetic absorption member is set on the rotating disc below the corresponding outlet pipe and the drainpipe.
6. POCT Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 4, which is characterized in that the wiper mechanism is also
Part is mixed including second, the second mixing part is set on the rotating disc, and the rotating disc turns to the reaction cup
It is abutted with the second mixing part.
7. POCT Full-automatic chemiluminescence immunoassay analysis meter as described in claim 1, which is characterized in that the reagent sample machine
Structure includes reagent sample disk and the second actuator for connecting with the reagent sample disk, and the reagent sample disk is rotatably dispose in institute
It states in rack, second actuator drives the reagent sample disk rotation so that the Reagent Tube and the sample tube turn to
Sample position.
8. POCT Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 7, which is characterized in that the reagent sample machine
Structure further includes shell, and the reagent sample disk is set in the shell, and it is mutually indepedent that the Reagent Tube is equipped at least two
Accommodating cavity, the inner walls be equipped with internal tooth, the accommodating cavity bottom on the outermost side be equipped with gear, the reagent sample
The gear and the interior tooth engagement are when the rotation of this disk to drive the accommodating cavity on the outermost side to rotate.
9. POCT Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 8, which is characterized in that the POCT is full-automatic
Chemical illumination immunity analysis instrument further includes sampling mechanism, and described using mechanism includes pedestal and sampling needle, the sampling needle with
The removable connection of the pedestal, is moved to the sample-adding position by the sampling position when sampling needle is moved along the pedestal, with
Reagent in sample and the Reagent Tube in the sample tube is added in the reaction cup with magnetic bead.
10. POCT Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 9, which is characterized in that the sampling mechanism
It further include the cleaning component for cleaning the sampling needle, the cleaning component is set on the motion track of the sampling needle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820859982.3U CN208297542U (en) | 2018-06-05 | 2018-06-05 | POCT Full-automatic chemiluminescence immunoassay analysis meter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820859982.3U CN208297542U (en) | 2018-06-05 | 2018-06-05 | POCT Full-automatic chemiluminescence immunoassay analysis meter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208297542U true CN208297542U (en) | 2018-12-28 |
Family
ID=64722594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820859982.3U Active CN208297542U (en) | 2018-06-05 | 2018-06-05 | POCT Full-automatic chemiluminescence immunoassay analysis meter |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208297542U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108469529A (en) * | 2018-06-05 | 2018-08-31 | 深圳天辰医疗科技有限公司 | POCT Full-automatic chemiluminescence immunoassay analysis meters |
| WO2021007825A1 (en) * | 2019-07-17 | 2021-01-21 | 深圳汇芯生物医疗科技有限公司 | Separation device and method for separating target particles in liquid samples |
| CN114384063A (en) * | 2022-03-23 | 2022-04-22 | 深圳天辰医疗科技有限公司 | Chemiluminescence apparatus |
-
2018
- 2018-06-05 CN CN201820859982.3U patent/CN208297542U/en active Active
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108469529A (en) * | 2018-06-05 | 2018-08-31 | 深圳天辰医疗科技有限公司 | POCT Full-automatic chemiluminescence immunoassay analysis meters |
| WO2021007825A1 (en) * | 2019-07-17 | 2021-01-21 | 深圳汇芯生物医疗科技有限公司 | Separation device and method for separating target particles in liquid samples |
| CN112601959A (en) * | 2019-07-17 | 2021-04-02 | 深圳汇芯生物医疗科技有限公司 | Separation device and method for separating target particles in liquid sample |
| JP2022541279A (en) * | 2019-07-17 | 2022-09-22 | 深▲せん▼匯芯生物医療科技有限公司 | Separation device and method for separating target particles in liquid samples |
| JP7312507B2 (en) | 2019-07-17 | 2023-07-21 | 深▲せん▼匯芯生物医療科技有限公司 | Separation device and method for separating target particles in liquid samples |
| US11874209B2 (en) | 2019-07-17 | 2024-01-16 | Shenzhen Huixin Life Technologies Co., Ltd | Isolation device and isolation method for isolating target particles from liquid samples |
| CN114384063A (en) * | 2022-03-23 | 2022-04-22 | 深圳天辰医疗科技有限公司 | Chemiluminescence apparatus |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108469529A (en) | POCT Full-automatic chemiluminescence immunoassay analysis meters | |
| CN208297542U (en) | POCT Full-automatic chemiluminescence immunoassay analysis meter | |
| CN109142768B (en) | Automatic analyzer and sample analyzing method | |
| CN109142766A (en) | Chemiluminescence detector | |
| CN110007099B (en) | Automatic analyzer and sample analyzing method | |
| CN205656203U (en) | A sampling device for immune quantitative analysis appearance | |
| CN106018784A (en) | Small electrochemical luminescence immunoassay analyzer and analysis method thereof | |
| CN105628947B (en) | Whole blood automatic luminous immunoassay instant detector | |
| CN104535782A (en) | Full-automatic immuno-fluorescence quantitative analysis device and implementation method | |
| CN103743916B (en) | A kind of Full-automatic chemiluminescence immunoassay analysis meter | |
| CN109061210A (en) | A kind of full-automatic illumination chemo-immunity analyzer | |
| CN104297498A (en) | Fully automatic biochemical and luminescent immunoassay system | |
| CN109856390A (en) | Miniature high-efficiency chemiluminescence immunoassay analyzer | |
| CN109975277A (en) | Chemiluminescence detector and its detection method | |
| CN102419375A (en) | Full-automatic chemoluminescence immunoassay analyzer | |
| CN111551758A (en) | Automatic analyzer | |
| CN205539017U (en) | Full -automatic portable chemiluminescent immunoassay analysis appearance | |
| WO2020062946A1 (en) | Magnetic bead cleaning device and chemiluminescence immunoassay analyzer | |
| CN208721691U (en) | A kind of luminescent chemical immunity analysis instrument | |
| CN104730262A (en) | Liquid detection device | |
| CN202166654U (en) | Full-automatic chemical luminescence immune analyzer | |
| CN108663502A (en) | Full-automatic thrombelastogram instrument | |
| CN104535760A (en) | Detecting box of chemiluminescence immunity analyzer | |
| CN108732163A (en) | Full-automatic chemiluminescence immunoassay analysis meter | |
| CN113267639A (en) | Automatic immunity analyzer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |