CN208297531U - Enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector - Google Patents
Enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector Download PDFInfo
- Publication number
- CN208297531U CN208297531U CN201721867113.7U CN201721867113U CN208297531U CN 208297531 U CN208297531 U CN 208297531U CN 201721867113 U CN201721867113 U CN 201721867113U CN 208297531 U CN208297531 U CN 208297531U
- Authority
- CN
- China
- Prior art keywords
- light
- enzyme
- light source
- exempts
- pallet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The utility model discloses a kind of enzymes to exempt from fluorogenic chemiluminescence composite type enzyme mark detector;It includes that seal casinghousing, pallet, movement mechanism, enzyme exempt from analytical equipment, fluorescence detection device, chemiluminescence detecting and master controller;It includes combined light source and silicon photocell plate that enzyme, which exempts from analytical equipment,;Combined light source includes multiple first light sources, multiple first light guide modules and fixing seat;Effect: under the guide-lighting effect of the first light guide module, the light for enabling first light source to issue is directed at the center of silicon photocell, so that can accurately project and pass through gaging hole to be checked and received by silicon photocell, so that enzyme exempt to analyze it is more acurrate, simultaneously, enzyme is exempted from analytical equipment by the utility model, fluorescence detection device and chemiluminescence detecting become one, so as to be configured to the composite type enzyme mark detector with comprehensive detection function, its enzyme being independently arranged compared to three exempts from analytical equipment, fluorescence detection device and chemiluminescence detecting, using more convenient, production cost can be lower.
Description
Technical field
The utility model relates to technical field of medical detection, in particular, being related to a kind of enzyme, to exempt from fluorogenic chemiluminescence comprehensive
Formula enzyme mark detector.
Background technique
Immunology detection is body identification " itself " and " non-oneself " antigen, is formed naturally to autoantibody as its name suggests
Immune tolerance generates a kind of detection of physiological function of repulsive interaction to " non-oneself " antigen.It mainly utilizes antigen and antibody
A kind of means for being detected of specific reaction, detection is believed since it can use isotope, enzyme, chemiluminescent substance etc.
It number amplifies and shows, therefore, be commonly used for detecting the micro substances such as protein, hormone.
Immunoassay has the different detections such as enzyme-labeled immunity detection, fluorescence immunoassay detection and chemiluminescence immunoassay detection
Mode.Enzyme used in enzyme-labeled immunity detection mode therein exempts from analytical equipment, generally comprises and is oppositely arranged from top to down
Lamp plate and silicon photocell plate, be provided with multiple light directions light source directed downwardly on corresponding lamp plate;On corresponding silicon photocell plate then
Equipped with the multiple silicon photocells opposite with multiple respective sources positions.When implementing enzyme-labeled immunity detection, then device is needed
The ELISA Plate of sample sheet is transferred between corresponding lamp plate and corresponding silicon photocell plate by used movement mechanism, so that phase
The light for answering light source to issue, which passes through device, corresponding detection hole on the ELISA Plate of sample to be examined, in this way, and respective sources
The opposite silicon photocell in position then receives passed through light, thus, it is able to achieve using colorimetric principle and treats sample sheet
It carries out enzyme and exempts from analysis detection, although such enzyme exempts from analytical equipment using extensively, it still has certain defect and deficiency.
Specifically, if the light source on lamp plate fills askew, then its light direction can be prevented from towards underface, so that
The center of the silicon photocell opposite with its position cannot be directed at, in this way, then prevent source light from accurately project and pass through to
Detection hole is received by silicon photocell, so that it is not accurate enough to there is a problem of that enzyme exempts to analyze.
Also, although enzyme-labeled immunity detection, fluorescence immunoassay detection and chemiluminescence immunoassay detection have his own strong points,
It is needed according to specific required and occasion come selection enzyme-labeled immunity detection device, fluorescence single or one by one in a particular application
Immunity testing equipment or chemiluminescence immunoassay detection device detect sample, in this way, then make it is cumbersome, meanwhile, it is right
It examines equipment and chemiluminescence immunoassay to examine equipment in independent enzyme-labeled immunity detection device, fluorescence immunoassay, is independently operated,
Obvious higher cost, and to be not easy to proofer using extremely inconvenience and one way in which is selected to carry out fastly as needed
Speed detection.
Whereby, it for status, designs a enzyme for exempting from analytical equipment with novel enzyme and exempts from fluorogenic chemiluminescence composite type
Enzyme mark detector, so that detection effect is good, detection quick, detection accurate, easy to detect has washability and it is at low cost etc. to make,
Then it is necessary.
Utility model content
A kind of enzyme provided the purpose of the utility model is to overcome the deficiency of the above-mentioned prior art exempts from fluorescence chemical hair
Light composite type enzyme mark detector.
The utility model solves technical solution used by prior art problem: it is comprehensive that a kind of enzyme exempts from fluorogenic chemiluminescence
Formula enzyme mark detector, comprising:
Seal casinghousing;
Pallet;The pallet is suitable for holding up the ELISA Plate for being equipped with sample to be examined;
Movement mechanism;The movement mechanism is set in the seal casinghousing, and is fixedly arranged on the pallet lower part, to drive
The pallet is moved to move with longitudinal direction in transverse direction;
Enzyme exempts from analytical equipment;The enzyme is exempted from analytical equipment and is set in the seal casinghousing, and is located at first position;
It includes combined light source and silicon photocell plate that the enzyme, which exempts from analytical equipment,;
Vertical stand is equipped with a hanging plate along the longitudinal direction in the seal casinghousing;The combined light source is fixedly arranged on the hanging plate
Side and be located above the pallet;The combined light source includes multiple uniformly distributed downwards in a manner of multiple rows of multiple row
First light source, the first light guide module for being correspondingly arranged in multiple first light source lower parts and the side for being fixedly arranged on the hanging plate
Fixing seat to the multiple first light sources of fixation and multiple first light guide modules;
The silicon photocell plate is set to below the pallet, and opposite with the combined light source, and the silicon photoelectricity
The upper surface of pond plate is evenly provided with multiple silicon photocells, the position pair of multiple silicon photocells in a manner of multiple rows of multiple row
It should be opposite with the position of multiple first light guide modules;
Fluorescence detection device;The fluorescence detection device is set in the seal casinghousing, and is located at the second position;
Chemiluminescence detecting;The chemiluminescence detecting is set in the seal casinghousing, and is located at third
Position;
Master controller;The master controller is connect with the movement mechanism signal, to control the movement mechanism driving
The pallet in transverse direction with longitudinal direction move so that the pallet be transported to the first position, the second position or
The third place exempts from analytical equipment, fluorescence detection device or chemiluminescence detecting to the enzyme mark by the enzyme with correspondence
The sample to be examined put on plate is analyzed and is detected.
Above technical scheme is further elaborated below:
Preferably, each first light guide module includes light-conductive optic fibre, convex lens A and filter A;
The fixing seat include pedestal, the fixed frame for being set to the pedestal top, it is multiple in a manner of multiple rows of multiple row consolidate
It light source base, more light-guiding pillars, the filter fixed plate for being fixedly arranged on the pedestal bottom surface on the fixed frame and is fixedly arranged on
The bottom plate of the filter fixed plate bottom surface;
A corresponding appearance for accommodating multiple first light sources is offered in the middle part of the upper surface of multiple light source bases downwards
Set chamber;One is offered on multiple light source bases downwards in the middle part of the inner bottom surface of corresponding accommodating cavity through the pedestal, filter
The guide-lighting slot of fixed plate and the bottom plate;The more light-guiding pillars are corresponding to be solidly plugged in multiple guide-lighting slots, is led described in more
Light beam axis offers an accommodating through the more light-conductive optic fibres of corresponding accommodating of lower end surface thereon along its length
Slot, and the corresponding inner bottom surface with multiple accommodating cavities in upper surface of the more light-guiding pillars is flush, the more light-guiding pillars
Lower end surface corresponding be located at middle part in the pedestal;
The bottom surface of the pedestal offers multiple internal diameters and the convex lens A outer diameter around multiple guide-lighting slots upwards
Compatible groove A;Multiple convex lens A correspondences are fastened in multiple groove A, and multiple convex lens A's is convex
Face is downward;The bottom surface of the filter fixed plate offers multiple internal diameters and the filter around multiple guide-lighting slots upwards
The compatible groove B of A outer diameter;Multiple filter A correspondences are fastened in multiple groove B, and multiple convex lens A
The light-conductive optic fibre fixed in the corresponding more light-guiding pillars for being located at relative position in center and the center of multiple filter A
Central axes on.
Preferably, the fixing seat further includes the cover board that multiple corresponding lids close multiple accommodating cavities, multiple cover boards
Upper surface it is corresponding offer so that power supply line pass through cross mouth.
Preferably, the fluorescence detection device includes second light source, the second light guide module and fluorescence detector;
Second light guide module includes light guide seat, convex lens B and filter B;
The light guide seat is fixedly connected with the fixing seat, and a V-type guide lighting channel is equipped in the light guide seat;The V
Type guide lighting channel includes be connected the entering light channel to form V-structure and optical channel out;The light inlet in the entering light channel and institute
The light-emitting window for stating out optical channel is respectively positioned on the light guide seat upper surface;The light-emitting window in the entering light channel and the optical channel out
Light inlet is mutually screwed on, and is located at the light guide seat bottom surface, and is located at the top of the pallet;The second light source is fixed downwards
At the light inlet in the entering light channel;The convex lens B is fixedly arranged in the entering light channel, and the convex surface of the convex lens B
Downward;The filter B is fixedly arranged in the optical channel out;The fluorescence detector is fixedly arranged on the light-emitting window of the optical channel out
Place.
Preferably, the center of the convex lens B is located in light direction and the entering light channel of the second light source
On axis;The center of the filter B is located on the central axes of optical channel out.
Preferably, the chemiluminescence detecting includes:
Photomultiplier tube;The photomultiplier tube is vertically installed in the seal casinghousing and is located at the upper of the pallet
Side;The lower end of the photomultiplier tube is incident window, and upper end is anode tap;
Photon counter;The photon counter is connected with the upper end of the photomultiplier tube;
Detect headgear;The movable lower end for being sheathed on the photomultiplier tube of the detection headgear;
Lifting device;The lifting device is connected with the detection headgear, to drive the detection headgear in the light
The lower end of electric multiplier tube slides up and down.
Preferably, the lifting device includes:
Fixed plate;The fixed plate is horizontal to be installed on the hanging plate;The photomultiplier tube is installed on the fixation
The lower section of plate;
Elevating lever, activity is worn in the fixed plate elevating lever in the vertical direction, the detection headgear and the liter
The lower end connection of bar is dropped;
Driving device, the driving device are connected with the upper end of the elevating lever, to drive the elevating lever vertically
Movement, and then drive the detection headgear to move up and down in the lower end of the photomultiplier tube by the elevating lever.
Preferably, the driving device includes:
Driving motor A;The driving motor A is installed on the upper surface of the fixed plate and connects with the master controller signal
It connects, and one eccentric wheel assembly of output axis connection of the driving motor A;The upper end of the elevating lever connects a linkage board, described
The lower surface of eccentric wheel assembly and the linkage board offsets, to drive the linkage by the eccentric motion of the eccentric wheel assembly
Plate moves upwards;
Spring, the spring pocket be set to the elevating lever on, and the spring be compressive state, the upper end of the spring with
The lower surface of the fixed plate offsets, and the upper end of the spring offsets with the detection headgear.
Preferably, two symmetrically arranged magnet are installed, the eccentric wheel assembly side is equipped on the eccentric wheel assembly
One Hall sensor being connect with the master controller signal;
When one of two magnet are opposite with the Hall sensor, the Hall sensor generates inductive signal, institute
State the position that master controller judges the detection headgear according to the inductive signal.
Preferably, which is characterized in that the movement mechanism includes:
Sliding rail;There are two the sliding rail is set, two sliding rails are set to the interior bottom of the seal casinghousing in transverse direction
Face, and the two sides of the corresponding inner bottom surface for being located at the seal casinghousing;
Sliding seat;There are two the sliding seat is set, two sliding seats are oppositely arranged, and are corresponded in transverse direction slidably
Be fixedly arranged on two sliding rails;
Grip block;The grip block is fixedly arranged on a wherein sliding seat side;
Driving motor B;The driving motor B be set to along the longitudinal direction the seal casinghousing inner bottom surface and with the master control
Device signal connection processed, and it is located at the grip block side;
Driving wheel;The driving wheel is fixedly arranged on the output shaft of the driving motor B;
Driven wheel;The driven wheel is set to the inner bottom surface of the seal casinghousing, and setting parallel with the driving wheel,
And the equal length of the spacing between the driven wheel and the driving wheel and the sliding rail;
Driving wheel band;The driving wheel band set is fixed on the driving wheel and the driven wheel, and the driving wheel band presss from both sides
It is fixed on the grip block;
Driving motor C;The driving motor C be fixedly arranged on a wherein sliding seat along the longitudinal direction and with the master control
Device signal connection processed;
Screw rod;One end of the screw rod is fixedly connected with the output shaft of the driving motor C, and the other end along the longitudinal direction may be used
Rotation is installed on another sliding seat;
Guide rod;The guide rod is fixed on along the longitudinal direction between two sliding seats;
Feed screw nut;The feed screw nut is threadedly engaged on the screw rod;
Sliding block;The sliding block is fixedly arranged on the feed screw nut, and is offered on the sliding block so that the guide rod is worn
The pilot hole crossed;
One end of the pallet is fixedly connected on the sliding block.
The beneficial effects of the utility model are:
A kind of enzyme provided by the utility model exempts from fluorogenic chemiluminescence composite type enzyme mark detector, in the specific implementation,
On the one hand, it includes combined light source and silicon photocell plate that set enzyme, which exempts from analytical equipment,;The combined light source includes multiple
Uniformly distributed first light source and the first of multiple first light source lower parts are correspondingly arranged in downwards in a manner of multiple rows of multiple row
Light guide module;The silicon photocell plate is opposite with the combined light source, and the upper surface of the silicon photocell plate is with multiple rows of multiple row
Mode be evenly provided with multiple silicon photocells, the position of multiple silicon photocells is corresponding with the multiple described first guide-lighting moulds
The position of block is opposite;When exempting from analysis to sample to be examined progress enzyme using the utility model, so that device has the enzyme of sample to be examined
Target is transferred into corresponding first light guide module and corresponding silicon photocell plate by used movement mechanism in company with the pallet
Between, so that the light that corresponding first light source issues guides and passes through the enzyme that device has sample to be examined through corresponding first light guide module
Corresponding detection hole on target, in this way, under the guide-lighting effect of corresponding first light guide module, i.e., so that corresponding first light source is sent out
The light direction of light out makes it possible to be aligned the center of the silicon photocell opposite with its position, so that accordingly towards underface
The light that first light source is issued can accurately project and pass through gaging hole to be checked and be received by corresponding silicon photocell, so that enzyme exempts to analyze
More acurrate, on the other hand, the utility model is not only provided with the enzyme in first position and exempts from analytical equipment, is additionally provided in second
The fluorescence detection device of position, the chemiluminescence detecting in the third place and the fitness machine for driving the tray motion
Structure, in this way, the tray motion for holding up the ELISA Plate for having sample to be examined can be driven by the movement mechanism to described first
It sets, the second position or the third place, analytical equipment, fluorescence detection device or chemiluminescence detection dress is exempted from by the enzyme with corresponding
Set and the sample to be examined put on the ELISA Plate analyzed and detected so that detection it is efficient and convenient, using efficient and convenient
And use is time saving and energy saving, and proofer can also select as needed one of detection mode or Through Several Survey Measure to treat sample
This is detected, and makes it possible to meet different detection demands, meanwhile, enzyme is exempted from analytical equipment, fluorescence detection by the utility model
Device and chemiluminescence detecting become one, so as to be configured to have the composite type enzyme mark of comprehensive detection function to detect
Instrument, the enzyme being independently arranged compared to three exempt from analytical equipment, fluorescence detection device and chemiluminescence detecting, occupied space
Can be smaller, production cost can be lower, and in turn, the utility model is practical, and use reliability is good and using effect is good.
Detailed description of the invention
Fig. 1 is the perspective view that the utility model enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector;
Fig. 2 is that the utility model enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector when removing the seal casinghousing
Overall structure diagram;
Fig. 3 is the overall structure diagram one of the combined light source in the utility model embodiment;
Fig. 4 is the exploded view one of the combined light source in the utility model embodiment;
Fig. 5 is the exploded view two of the combined light source in the utility model embodiment;
Fig. 6 is the overall structure diagram of the fluorescence detection device in the utility model embodiment;
Fig. 7 is the main view sectional view of the fluorescence detection device in the utility model embodiment;
Fig. 8 is the overall structure diagram of the chemiluminescence detecting in the utility model embodiment;
Fig. 9 is overall structure diagram of the motion structure at a wherein visual angle in the utility model embodiment;
The embodiments will be further described with reference to the accompanying drawings for the realization, functional characteristics and advantage of the utility model aim.
Drawing reference numeral:
Seal casinghousing 10;
Hanging plate 101;Bracket 102;Top plate 103;Door closure 104;
Pallet 20;
ELISA Plate 30;
Detection hole 301;
Movement mechanism 40;
Sliding rail 401;Sliding seat 402;Grip block 403;Driving motor B404;Driving wheel 405;Driven wheel 406;Driving wheel band
407;Driving motor C408;Screw rod 409;Guide rod 410;Feed screw nut 411;Sliding block 412;
Enzyme exempts from analytical equipment 50;
Combined light source 51;First light source 511;First light guide module 512;Light-conductive optic fibre 5121;Convex lens A5122;Filter
Mirror A5123;Fixing seat 513;Pedestal 5131;Groove A51311;Screw hole A51312;Fixed frame 5132;Light source base 5133;Accommodating cavity
51331;Guide-lighting slot 51332;Fixation hole B51333;Light-guiding pillar 5134;Accommodation groove 51341;Filter fixed plate 5135;Groove
B51351;Screw hole B51352;Bottom plate 5136;Screw hole C51361;Cover board 5137;Cross mouth 51371;Fixation hole A51372;Silicon photoelectricity
Pond plate 52;Silicon photocell 521;
Fluorescence detection device 60;
Second light source 61;Second light guide module 62;Light guide seat 621;V-type guide lighting channel 6211;Entering light channel 6211A;Out
Optical channel 6211B;Inner edge A 6212;Inner edge B6213;Recessed rank 6214;Convex lens B622;Filter B623;Fluorescence detector 63;
Chemiluminescence detecting 70;
Photomultiplier tube 71;Photon counter 72;Detect headgear 73;Lifting device 74;Fixed plate 741;Elevating lever 742;
Driving device 743;Driving motor A7431;Eccentric wheel assembly 7432;Linkage board 7433;
Specific embodiment
The technical solution of the utility model is described in detail below with reference to drawings and the specific embodiments, to become apparent from, directly
See the utility model essence that ground understands the utility model.
In conjunction with shown in Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6, Fig. 7, Fig. 8 and Fig. 9;
A kind of enzyme provided by the utility model exempts from fluorogenic chemiluminescence composite type enzyme mark detector, comprising:
Seal casinghousing 10;The seal casinghousing 10 is for providing a closed darkroom, in order to the optics of sample to be examined
Detection.
Pallet 20;The pallet 20 is suitable for holding up the ELISA Plate 30 for being equipped with sample to be examined;The upper surface of the ELISA Plate 30
Uniformly offer multiple detection holes 301 to device sample to be examined downwards in a manner of multiple rows of multiple row;
Movement mechanism 40;The movement mechanism 40 is set in the seal casinghousing 10, and is fixedly arranged under the pallet 20
Portion, to drive the pallet 20 to move in transverse direction with longitudinal direction;
Enzyme exempts from analytical equipment 50;The enzyme is exempted from analytical equipment 50 and is set in the seal casinghousing 10, and is located at first
It sets;
It includes combined light source 51 and silicon photocell plate 52 that the enzyme, which exempts from analytical equipment 50,;
Vertical stand is equipped with a hanging plate 101 along the longitudinal direction in the seal casinghousing 10;The combined light source 51 is fixedly arranged on
The side of the hanging plate 101 and it is located at 20 top of the pallet;The combined light source 51 includes multiple sides with multiple rows of multiple row
The downward uniformly distributed first light source 511 of formula, the first light guide module for being correspondingly arranged in multiple 511 lower parts of the first light source
512 and be fixedly arranged on the hanging plate 101 side to the multiple first light sources 511 of fixation and multiple first guide-lighting moulds
The fixing seat 513 of block 512;
The silicon photocell plate 52 is set to 20 lower section of pallet, and opposite and described with the combined light source 51
The upper surface of silicon photocell plate 52 is evenly provided with multiple silicon photocells 521, multiple silicon light in a manner of multiple rows of multiple row
The position correspondence of battery 521 is opposite with the position of multiple first light guide modules 512;
Fluorescence detection device 60;The fluorescence detection device 60 is set in the seal casinghousing 10, and is located at second
It sets;
Chemiluminescence detecting 70;The chemiluminescence detecting 70 is set in the seal casinghousing 10, and position
In the third place;
Herein, that is to say, that the enzyme exempts from analytical equipment 50, fluorescence detection device 60 and chemiluminescence detecting 70 then
It is set to three different positions in the seal casinghousing 10.
Master controller;The master controller is connect with 40 signal of movement mechanism, to control the movement mechanism 40
The pallet 20 is driven to move in transverse direction with longitudinal direction, so that the pallet 20 is transported to the first position, the
Two positions or the third place exempt from analytical equipment 50, fluorescence detection device 60 or chemiluminescence detection dress by the enzyme with corresponding
The sample to be examined put on 70 pairs of ELISA Plates 30 is set to be analyzed and detected.
Based on described above, it is clear that, it is comprehensive that a kind of enzyme provided by the utility model exempts from fluorogenic chemiluminescence
Formula enzyme mark detector, in the specific implementation:
On the one hand, exempting from analytical equipment 50 because of set enzyme includes combined light source 51 and silicon photocell plate 52;Described group
Box-like light source 51 includes multiple uniformly distributed first light sources 511 downward in a manner of multiple rows of multiple row and is correspondingly arranged in multiple institutes
State the first light guide module 512 of 511 lower part of first light source;The silicon photocell plate 52 is opposite with the combined light source 51, institute
The upper surface for stating silicon photocell plate 52 is evenly provided with multiple silicon photocells 521, multiple silicon in a manner of multiple rows of multiple row
The position correspondence of photocell 521 is opposite with the position of multiple first light guide modules 512;In use the utility model to be checked
When sample progress enzyme exempts from analysis, so that device has the ELISA Plate 30 of sample to be examined to pass through used movement in company with the pallet 20
Mechanism 40 is transferred between corresponding first light guide module 512 and corresponding silicon photocell plate 52, so that corresponding first light source 511 is sent out
Light out, which guides through corresponding first light guide module 512 and passes through device, corresponding detection hole on the ELISA Plate 30 of sample to be examined
301, in this way, under the guide-lighting effect of corresponding first light guide module 512, i.e., so that the light that corresponding first light source 511 is issued
Light direction towards underface, make it possible to be aligned the center of the silicon photocell 521 opposite with its position, so that corresponding first light
The light that source 511 is issued can accurately project and pass through gaging hole 301 to be checked and be connect by the opposite corresponding silicon photocell 521 in position
It receives, so that multiple silicon photocells 521, when realizing that sample to be examined enzyme exempts from analysis detection using colorimetric principle, enzyme exempts from analysis more
Accurately.
On the other hand, exempt from analytical equipment 50 because the utility model is not only provided with the enzyme in first position, be additionally provided with place
In the fluorescence detection device 60 of the second position, the chemiluminescence detecting 70 in the third place and the pallet 20 is driven to be transported
Dynamic movement mechanism 40, in this way, the pallet for holding up the ELISA Plate 30 for having sample to be examined can be driven by the movement mechanism 40
20 move to the first position, the second position or the third place, exempt from analytical equipment 50, fluorescence detection by the enzyme with correspondence
Device 60 or chemiluminescence detecting 70 are analyzed and are detected to the sample to be examined put on the ELISA Plate 30, so that
It is efficient and convenient, time saving and energy saving using efficient and convenient and use to detect, and proofer can also select one of detection as needed
Mode or Through Several Survey Measure detect sample to be examined, make it possible to meet different detection demands.
Meanwhile enzyme is exempted from analytical equipment 50, fluorescence detection device 60 and chemiluminescence detecting 70 and collected by the utility model
It is integrally formed, so as to be configured to the composite type enzyme mark detector with comprehensive detection function, is independently arranged compared to three
Enzyme exempts from analytical equipment 50, fluorescence detection device 60 and chemiluminescence detecting 70, and occupied space can be smaller, and production cost can be more
It is low.
In turn, the utility model is practical, and use reliability is good and using effect is good.
It is emphasized that in the technical scheme, each first light guide module 512 includes light-conductive optic fibre
5121, convex lens A5122 and filter A5123;
The fixing seat 513 include pedestal 5131, be set to 5131 top of pedestal with its integrally formed fixation
Frame 5132, multiple light source bases 5133 being fixedly arranged in a manner of multiple rows of multiple row on the fixed frame 5132, more light-guiding pillars 5134,
It is fixedly arranged on the filter fixed plate 5135 of 5131 bottom surface of pedestal and is fixedly arranged on the bottom of 5135 bottom surface of filter fixed plate
Plate 5136;
Preferably, in the technical scheme, the bottom surface of the pedestal 5131 uniformly offers multiple screw hole A51312;
The bottom surface of the filter fixed plate 5135, which uniformly offers, multiple is through to end face thereon and correspondence and multiple screw holes
The opposite screw hole B51352 in the position A51312;The bottom surface of the bottom plate 5136, which uniformly offers, multiple is through to end face thereon
And the corresponding screw hole C51361 opposite with multiple positions the screw hole B51352;
In this way, the bottom plate 5136 and the filter fixed plate 5135 then by screw in the opposite screw hole C51361 in position,
The clamping screw of screw hole B51352 and screw hole A51312 and be fixedly connected with the pedestal 5131, stationarity is good between its
While, disassembly also facilitates each other, so that convenient for safeguarding.
Preferably, in the technical scheme, a pair is offered downwards in the middle part of the upper surface of multiple light source bases 5133
The accommodating cavity 51331 of multiple first light sources 511 should be accommodated;In corresponding accommodating cavity 51331 on multiple light source bases 5133
Inner bottom surface in the middle part of downwards offer one run through the pedestal 5131, filter fixed plate 5135 and the bottom plate 5136 leaded light
Slot 51332;The more light-guiding pillars 5134 are corresponding to be solidly plugged in multiple guide-lighting slots 51332, the more light-guiding pillars 5134
Axis offers an accommodating through the more light-conductive optic fibres 5121 of corresponding accommodating of lower end surface thereon along its length
Slot 51341, and the corresponding inner bottom surface with multiple accommodating cavities 51331 in upper surface of the more light-guiding pillars 5134 is flush,
The lower end surface of the more light-guiding pillars 5134 is corresponding to be located at middle part in the pedestal 5131;
The bottom surface of the pedestal 5131 around multiple guide-lighting slots 51332 offer upwards multiple internal diameters with it is described convex
The compatible groove A51311 of lens A5122 outer diameter;Multiple convex lens A5122 correspondences are fastened in multiple grooves
In A51311, and the convex surface of multiple convex lens A5122 is downward;The bottom surface of the filter fixed plate 5135 is around multiple
The leaded light slot 51332 offers multiple internal diameters groove B50351 compatible with the filter A5123 outer diameter upwards;Multiple institutes
It states filter A5123 correspondence to be fastened in multiple groove B50351, and the center of multiple convex lens A5122 and multiple institutes
State the light-conductive optic fibre 5121 fixed in the corresponding more light-guiding pillars 5134 for being located at relative position in center of filter A5123
Central axes on.
In this way, multiple first light sources 511 of i.e. toilet device are askew in assembly fashionable dress, multiple first light sources 511 are sent out
Light out can be directed at by the more piece light-conductive optic fibres 5121 opposite with its position opposite with its position multiple well
The convex lens A5122 carries out optically focused, forms point light source to enable good, is formed by point light source by corresponding position
After the filter A5123 carries out the filtering of light wave, and the light wave that can effectively filter out unwanted wavelength can be made, then made
The light wave of wavelength required for obtaining can accurately be projected in the form of point light source and pass through gaging hole 301 to be checked by the silicon photoelectricity of relative position
Pond 521 receives, so that enzyme is exempted from, analytical effect is more preferable and to make enzyme exempt from analysis more accurate.
To which the using effect of the utility model can effectively improve.
Also, in the technical scheme, the fixing seat 513 further includes that multiple corresponding lids close multiple accommodating cavities
The upper surface correspondence of 51331 cover board 5137, multiple cover boards 5137 offers so that the mouth 51371 excessively that power supply line passes through.
Preferably, in the technical scheme, the upper surface of multiple cover boards 5137 offers a fixation hole respectively
A51372;The upper surface of multiple light source bases 5133 offers the fixation hole on the cover board 5137 with relative position respectively
The position A51372 is relatively fixed hole B51333;The fixation hole of multiple cover boards 5137 by screwing in relative position
The fastening bolt of A51372 and the fixation hole B51333 and correspondence be fixedly connected with multiple light source bases 5133.
Preferably, in the present embodiment, the fluorescence detection device 60 include second light source 61, the second light guide module 62 and
Fluorescence detector 63;
Second light guide module 62 includes light guide seat 621, convex lens B622 and filter B623;
The light guide seat 621 is fixedly connected with the fixing seat 513, and it is logical that a V-type leaded light is equipped in the light guide seat 621
Road 6211;The V-type guide lighting channel 6211 includes the entering light channel 6211A and optical channel out for being connected and forming V-structure
6211B;The light-emitting window of the light inlet of the entering light channel 6211A and the optical channel 6211B out are respectively positioned on the light guide seat 621
Upper surface;The light-emitting window of the entering light channel 6211A and the light inlet of the optical channel 6211B out are mutually screwed on, and are located at described
621 bottom surface of light guide seat, and it is located at the top of the pallet 20;The second light source 61 is fixedly arranged on downwards the entering light channel
At the light inlet of 6211A;The convex lens B622 is fixedly arranged in the entering light channel 6211A, and the convex lens B622's is convex
Down;The filter B623 is fixedly arranged in the optical channel 6211B out;It is logical that the fluorescence detector 63 is fixedly arranged on the light out
At the light-emitting window of road 6211B.
Preferably, the center of the convex lens B622 be located at the second light source 61 light direction and the entering light channel
On the central axes of 6211A;The center of the filter B623 is located on the central axes of optical channel 6211B out.
Based on described above, when carrying out fluorescence detection to sample to be examined using the utility model so that device have it is to be checked
The ELISA Plate 30 of sample is transferred into corresponding second light guide module 62 by used movement mechanism 40 in company with the pallet 20
Lower section so that the light that corresponding second light source 61 issues guide through corresponding second light guide module 62 and needs sample across device
Corresponding detection hole 301 on this ELISA Plate 30.
In this way, the light that is issued of the second light source 61 is after the convex lens B622 of relative position carries out optically focused,
Point light source is formed, so that energy of light source is big, is formed by point light source in the light-emitting window for accurately passing through the entering light channel 6211A
It is accurately projected in the sample to be examined in the detection hole 301 of ELISA Plate 30 afterwards, enables sample to be examined in detection hole 301
Fluorescence is generated well, and generated fluorescence can be reflected on the filter B623 of corresponding position, so as to carry out light wave
Filtering so that the light wave of other unwanted wavelength can be filtered out effectively, the light wave of wavelength required for then enabling
It accurately passes through the light-emitting window of optical channel 6211B out and is sent to the detection that the fluorescence detector 63 carries out fluorescence, make
It obtains and cooperates fluorescence detector 63 relative to traditional y-type optical fiber, incident light source energy is bigger, and excitation sample to be examined generates fluorescence effect
Fruit is more preferable, and structure is simpler and makes cost lower.
In turn, the using effect of the utility model can be further enhanced.
Herein, you need to add is that, in the specific implementation, it is described go out optical channel 6211B in, the filter B623 with
Convex surface convex lens C (not shown) directed downwardly is fixedly provided between the light-emitting window of optical channel 6211B out;
In this way, generated fluorescence is reflected on the filter B623 of corresponding position, so as to the filtering of light wave is carried out,
So that the light wave of required wavelength can pass through the institute of corresponding position after effectively filtering out the light waves of other unwanted wavelength
It is not shown to state convex lens C) carry out light direction correction so that project light light-emitting angle will not dissociate and intersect so that
The directional light parallel with multiple central axes of optical channel 6211B out can be formed well, so that can be accurate after injection
Pass through it is described go out optical channel 6211B light-emitting window and accurately sent to the fluorescence detector 63 and carry out the detection of fluorescence,
Fluorescence detection effect is enabled to reach more preferable.
Herein, it should be noted that in the specific implementation, a circle is installed in the entering light channel 6211A to hold up
A circle is installed with to hold up the filter in the middle part of the inner edge A6212 of the convex lens B622, the optical channel 6211B out
The inner edge B6213 of B623, the internal diameter on the top of optical channel 6211B out is slightly larger than the middle part of optical channel 6211B out
Internal diameter, in this way, the convex lens C is then held up by the recessed rank 6214 and fixed i.e. so that its screw-on place is formed as a recessed rank 6214.
Preferably, in the specific implementation, the outer diameter of the convex lens B622 and the internal diameter of the entering light channel 6211A are mutually fitted
Match, the outer diameter of the filter B623 with it is described go out optical channel 6211B middle part internal diameter be adapted, the outer diameter of the convex lens C with
The upper inner diameter of the optical channel 6211B out is adapted;And the upper end of the inner edge A6212 downwards concave shape become with it is described
The compatible concave surface A in the lower part convex surface of convex lens B622;The upper end of the recessed rank 6214 downwards concave shape become with it is described convex
The compatible concave surface C in the lower part convex surface of lens C;In this way, i.e. so that the convex lens B622 and convex lens C placement is firm.
Further, in the present embodiment, the chemiluminescence detecting 70 includes:
Photomultiplier tube 71;The photomultiplier tube 71 is vertically installed in the seal casinghousing 10 and is located at the pallet
20 top;The lower end of the photomultiplier tube 71 is incident window, and upper end is anode tap;
Photon counter 72;The photon counter 72 is connected with the upper end of the photomultiplier tube 71;The capsul
The inner bottom surface of body 10 is equipped with a bracket 102 to prop the hanging plate 101, and 102 top horizontal of bracket is equipped with a top
Plate 103, the photon counter 72 are fixedly arranged on 103 bottom surface of top plate.
Detect headgear 73;The movable lower end for being sheathed on the photomultiplier tube 71 of the detection headgear 73;
Lifting device 74;The lifting device 74 is connected with the detection headgear 73, to drive the detection headgear 73
It is slided up and down in the lower end of the photomultiplier tube 71.
In this way, when the movement mechanism 40 drives the pallet 20 to move to the lower section of the photomultiplier tube 71, it can
The detection headgear 73 is driven to decline by the lifting device 74, so that the enzyme on the detection headgear 73 and the pallet 20
Target 30 is bonded, at this point, the incident window of the photomultiplier tube 71 can receive the inspection of the ELISA Plate 30 on the pallet 20
The light that the sample to be examined of institute's device issues in gaging hole 301, and amplified by the photomultiplier tube 71, and by described
Photon counter 72 carries out photon counting, that is, realizes to institute's device in the detection hole 301 of the ELISA Plate 30 on the pallet 20
Sample to be examined carries out chemiluminescence detection.
In the specific implementation, the lifting device 74 includes:
Fixed plate 741;The fixed plate 741 is horizontal to be installed on the hanging plate 101;The photomultiplier tube 71 is installed
In the lower section of the fixed plate 741;
Elevating lever 742, activity is worn in the fixed plate 741 elevating lever 742 in the vertical direction, the detection headgear
73 connect with the lower end of the elevating lever 742;Preferably, the elevating lever 742 is set as two, two elevating levers 742
Vertical and parallel is threaded through in the fixed plate 741.
Driving device 743, the driving device 743 is connected with the upper end of the elevating lever 742, to drive the lifting
Bar 742 vertically moves, and then drives the detection headgear 73 under the photomultiplier tube 71 by the elevating lever 742
End moves up and down.
In the specific implementation, the driving device 743 includes:
Driving motor A7431;The driving motor A7431 be installed on the upper surface of the fixed plate 741 and with the master
Controller signals connection, and one eccentric wheel assembly 7432 of output axis connection of the driving motor A7431;The elevating lever 742
Upper end level one linkage board 7433 of connection, the lower surface of the eccentric wheel assembly 7432 and the linkage board 7433 offsets,
To drive the linkage board 7433 to move upwards by the eccentric motion of the eccentric wheel assembly 7432;
Spring (not shown), the spring (not shown) is sheathed on the elevating lever 742, and the spring (not shown)
For compressive state, the upper end of the spring (not shown) and the lower surface of the fixed plate 741 offset, the spring (not shown)
Upper end offset with the detection headgear 73.
Based on described above, when carrying out chemiluminescence detection to sample to be examined using the utility model, so that device has
The ELISA Plate 30 of sample to be examined is transferred into corresponding detection headgear 73 by used movement mechanism 40 in company with the pallet 20
Lower section so that device has corresponding 301 face of detection hole on the ELISA Plate 30 of sample to be examined accordingly to detect headgear 73.
During carrying out chemiluminescence detection, when the movement mechanism 40 drives the pallet 20 to move to the light
It when under electric multiplier tube 71, then drives the elevating lever 742 to move downward by the driving device 743, and then drives the inspection
Gauge head set 73 slides down to desired height position in 71 lower end of photomultiplier tube, described in the desired height position
Detection 73 lower part of headgear can just fit with the ELISA Plate 30 held up on the pallet 20, on the ELISA Plate 30
The light that sample to be examined issues can enter to the incident window of the photomultiplier tube 71 by the detection headgear 73.
Herein, also need to show is, on the one hand, when driving motor A7431 work, the driving motor A7431
Output shaft the eccentric wheel assembly 7432 can be driven to rotate, can be by the linkage in the eccentric wheel assembly 7432 rotation
Plate 7433 is raised (extreme higher position), the linkage board 7433 be further driven to the elevating lever 742 and the detection headgear 73 to
Upper movement, at this point, the detection headgear 73 can be separated with the ELISA Plate 30 of lower section.On the other hand, the spring (not shown)
In confined state, so providing elastic reaction, which can force the detection headgear 73 and the elevating lever
742 move downward.That is, the driving motor A7431 do not drive the eccentric wheel assembly 7432 to rotate and to institute
When stating linkage board 7433 and generating upward active force, the elastic acting force of the spring (not shown) can make the detector
Set 73 and the elevating lever 742 drop to extreme lower position (spring (not shown) plays the role of elastic reset), at this point, the detection
Headgear 73 can be bonded with the ELISA Plate 30 of lower section;And when driving motor work, drive the eccentric wheel assembly 7432
When rotating and generating upward active force to the linkage board 7433, the linkage board 7433 is raised into (extreme higher position), it is described
Linkage board 7433 is further driven to the elevating lever 742 and the detection headgear 73 moves upwards, spring (not shown) quilt
Further compression.
To which the lifting can be realized in conjunction with the driving motor A7431 and the spring (not shown) alternating action
The driving that bar 742 and the detection headgear 73 move up and down.
So, on the one hand, in the detection process, be bonded after being declined by the detection headgear with the ELISA Plate 30 come shape
At sealing path channels, so that the light that the sample to be examined in the detection hole 301 of ELISA Plate 30 issues is by accordingly sealing optical path
Channel can conduct the accuracy and precision for making it possible to effectively improve detection to the incident window of the photomultiplier tube 71,
On the other hand, then it makes it possible to that the photomultiplier tube 71 is effectively avoided directly to contact with ELISA Plate 30 and to corresponding photomultiplier transit
Pipe 71 causes to damage.
In turn, the using effect of the utility model can be improved further.
Supplement is needed further exist for, in the specific implementation, two is equipped on the eccentric wheel assembly 7432 and is symmetrical arranged
Magnet, 7432 side of eccentric wheel assembly be equipped with a Hall sensor being connect with the master controller signal;
When one of two magnet are opposite with the Hall sensor, the Hall sensor generates inductive signal, institute
State the position that master controller judges the detection headgear 73 according to the inductive signal.
That is, can be detected the eccentric wheel assembly by the induction of the magnet and the Hall sensor
7432 state, when the eccentric wheel assembly 7432 is jack-up state, then the linkage board 7433 drives the elevating lever 742
Rise, corresponding, the detection headgear 73 is then to be located at higher position, that is to say and is in and 30 discrete state of ELISA Plate.And
When the eccentric wheel assembly 7432 is not jack up state, then make the elevating lever under the action of spring (not shown)
742 declines, corresponding, the detection headgear 73 is then to be located at lower position, be that is to say in the shape being bonded with ELISA Plate 30
State.
In this way, may be implemented to carry out detection process by the detection of the position (or state) to the detection headgear 73
Accurately control, and then realize continuous detection operation and improve its working efficiency.
And in all of above embodiment, in the specific implementation, the movement mechanism 40 includes: the utility model
Sliding rail 401;There are two the sliding rail 401 is set, two sliding rails 401 are set to the capsul in transverse direction
The inner bottom surface of body 10, and the two sides of the corresponding inner bottom surface for being located at the seal casinghousing 10;
Sliding seat 402;There are two the sliding seat 402 is set, two sliding seats 402 are oppositely arranged, and in transverse direction
Correspondence is slidably fixedly arranged on two sliding rails 401;
Grip block 403;The grip block 403 is fixedly arranged on wherein 402 side of sliding seat;
Driving motor B404;The driving motor B404 be set to along the longitudinal direction 10 inner bottom surface of seal casinghousing and with
The master controller signal connection, and it is located at 403 side of grip block;
Driving wheel 405;The driving wheel 405 is fixedly arranged on the output shaft of the driving motor B404;
Driven wheel 406;The driven wheel 406 is set to the inner bottom surface of the seal casinghousing 10, and with the driving wheel 405
Parallel setting, and the equal length of the spacing between the driven wheel 406 and the driving wheel 405 and the sliding rail 401;
Driving wheel band 407;407 sets of the driving wheel band is fixed on the driving wheel 405 and the driven wheel 406, and institute
Driving wheel band 407 is stated to be clamped on the grip block 403;
In this way, the driving wheel 405 will drive 407 turns of the driving wheel band in driving motor B404 work
Dynamic, the driving wheel band 407 then will drive the grip block 403 and move in transverse direction.
Driving motor C408;The driving motor C408 is fixedly arranged on a wherein sliding seat 402 simultaneously along the longitudinal direction
It is connect with the master controller signal;
Screw rod 409;One end of the screw rod 409 is fixedly connected with the output shaft of the driving motor C408, other end edge
Longitudinal direction is rotatably installed on another sliding seat 402;
Guide rod 410;The guide rod 410 is fixed on along the longitudinal direction between two sliding seats 402;
Feed screw nut 411;The feed screw nut 411 is threadedly engaged on the screw rod 409;
Sliding block 412;The sliding block 412 is fixedly arranged on the feed screw nut 411, and offered on the sliding block 412 so that
The pilot hole that the guide rod 410 passes through;
In this way, the screw rod 409 will drive the sliding block 412 and lead along described in driving motor C408 work
It slides, i.e., is moved along the longitudinal direction to bar 410.
And one end of the pallet 20 is fixedly connected on the sliding block 412.And along longitudinal direction because of the driving motor C408
Direction is fixedly arranged on a wherein sliding seat 402 and connect with the master controller signal;One end of the screw rod 409 and institute
The output shaft for stating driving motor C408 is fixedly connected, and the other end is rotatably installed on another sliding seat along the longitudinal direction
On 402;
In this way, realizing that the pallet 20, can under the driving of the driving motor B404 and the driving motor C408
Correspondence is moved in transverse direction and is moved along the longitudinal direction, so that it can be transferred into the first position, the second position and institute
It states the third place and corresponds to and 70 pairs of analytical equipment 50, fluorescence detection device 60 or chemiluminescence detecting institutes are exempted from by the enzyme
The sample to be examined put on the ELISA Plate 30 that pallet 20 is held up is stated to be analyzed and detected.
In conjunction with described above, it is clear that, in the movement mechanism 40, transverse direction is using transmission V belt translation dress
Set the transmission pallet 20 to move, longitudinal direction transmits the pallet 20 using spindle gear and moves, on the one hand, i.e. so that
Entire movement mechanism 40 is simple and clear, so that easy to disassemble and maintenance, on the other hand, motion stabilization is reliable, kinematic error
It is small, enable the pallet 20 to be accurately sent to specified coordinate position and in case inspection on the ELISA Plate 30 held up thereon
The detection of the sample to be examined of institute's device in gaging hole 301.
In turn, the using effect of the utility model can reach best.
And preferably, in the technical scheme, a side end face lower part of the seal casinghousing 10 is equipped with a door closure 104, institute
It states door closure 104 to remove out of described seal casinghousing 10 suitable for the pallet 20, in this way, the fortune can be passed through before detection
Motivation structure 40 drives the pallet 20 to be moved to outside the seal casinghousing 10 from the door closure 104, then will be loaded with to sample
This ELISA Plate 30 is placed on the pallet 20, is then held up by the movement mechanism 40 by the pallet 20 and thereon
ELISA Plate 30 be moved to inside the seal casinghousing 10, finally close the door closure 104, the optics of sample to be examined can be carried out
Analysis and detection open the door closure 104 after analysis detection test, by the movement mechanism 40 by the pallet
20 and the ELISA Plate 30 that is held up thereon to be moved to the seal casinghousing 10 outer, in this way, facilitating operation, conveniently will test
The device that the ELISA Plate 30 finished unloads and loads onto next batch has the ELISA Plate 30 of sample to be examined.
Other embodiments etc., here, not illustrating one by one.
In conclusion the utility model overall structure is simple, easily implement, easy to operate, practical, specificity is strong, so that
The utility model necessarily has good market popularization value, and the utility model can be very welcome, can effectively be popularized.
The above is only the preferred embodiment of the present invention, is not intended to limit the patent protection of the utility model
Range, the transformation of equivalent structure or equivalent process made by all specifications and accompanying drawing content using the utility model, or it is straight
It connects or is used in other related technical areas indirectly, be also included in the patent protection scope of the utility model.
Claims (9)
1. a kind of enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector characterized by comprising
Seal casinghousing;
Pallet;The pallet is suitable for holding up the ELISA Plate for being equipped with sample to be examined;
Movement mechanism;The movement mechanism is set in the seal casinghousing, and is fixedly arranged on the pallet lower part, to drive
Pallet is stated to move with longitudinal direction in transverse direction;
Enzyme exempts from analytical equipment;The enzyme is exempted from analytical equipment and is set in the seal casinghousing, and is located at first position;
It includes combined light source and silicon photocell plate that the enzyme, which exempts from analytical equipment,;
Vertical stand is equipped with a hanging plate along the longitudinal direction in the seal casinghousing;The combined light source is fixedly arranged on the one of the hanging plate
Side and it is located above the pallet;The combined light source includes multiple in a manner of multiple rows of multiple row downwards uniformly distributed first
Light source, the first light guide module for being correspondingly arranged in multiple first light source lower parts and the side for being fixedly arranged on the hanging plate to
The fixing seat of the fixed multiple first light sources and multiple first light guide modules;
The silicon photocell plate is set to below the pallet, and opposite with the combined light source, and the silicon photocell plate
Upper surface be evenly provided with multiple silicon photocells in a manner of multiple rows of multiple row, the position of multiple silicon photocells it is corresponding with
The position of multiple first light guide modules is opposite;
Fluorescence detection device;The fluorescence detection device is set in the seal casinghousing, and is located at the second position;
Chemiluminescence detecting;The chemiluminescence detecting is set in the seal casinghousing, and is located at the third place;
Master controller;The master controller is connect with the movement mechanism signal, to control described in the movement mechanism driving
Pallet is moved with longitudinal direction in transverse direction, so that the pallet is transported to the first position, the second position or third
Analytical equipment, fluorescence detection device or chemiluminescence detecting are exempted on the ELISA Plate by the enzyme with correspondence in position
The sample to be examined put is analyzed and is detected;
Each first light guide module includes light-conductive optic fibre, convex lens A and filter A;
The fixing seat is included pedestal, the fixed frame for being set to the pedestal top, multiple is fixedly arranged in a manner of multiple rows of multiple row
It light source base, more light-guiding pillars, the filter fixed plate for being fixedly arranged on the pedestal bottom surface on the fixed frame and is fixedly arranged on described
The bottom plate of filter fixed plate bottom surface;
A corresponding accommodating cavity for accommodating multiple first light sources is offered in the middle part of the upper surface of multiple light source bases downwards;
One is offered on multiple light source bases downwards in the middle part of the inner bottom surface of corresponding accommodating cavity through the pedestal, filter fixed plate
And the guide-lighting slot of the bottom plate;The more light-guiding pillars are corresponding to be solidly plugged in multiple guide-lighting slots, in the more light-guiding pillars
Axis offers an accommodation groove through the more light-conductive optic fibres of corresponding accommodating of lower end surface thereon along its length, and more
The corresponding inner bottom surface with multiple accommodating cavities in the upper surface of light-guiding pillar described in root is flush, the lower end surface of the more light-guiding pillars
It is corresponding to be located at middle part in the pedestal;
The bottom surface of the pedestal offers multiple internal diameters around multiple guide-lighting slots upwards and mutually fits with the convex lens A outer diameter
The groove A matched;Multiple convex lens A correspondences are fastened in multiple groove A, and the convex surface of multiple convex lens A is equal
Downward;The bottom surface of the filter fixed plate offers outside multiple internal diameters and the filter A upwards around multiple guide-lighting slots
The compatible groove B of diameter;Multiple filter A correspondences are fastened in multiple groove B, and in multiple convex lens A
The light-conductive optic fibre fixed in the corresponding more light-guiding pillars for being located at relative position in the center of the heart and multiple filter A
On central axes.
2. enzyme according to claim 1 exempts from fluorogenic chemiluminescence composite type enzyme mark detector, which is characterized in that the fixation
Seat further includes the cover board that multiple corresponding lids close multiple accommodating cavities, and the upper surface of multiple cover boards is corresponding to be offered so that electricity
What source line passed through crosses mouth.
3. enzyme according to claim 1 exempts from fluorogenic chemiluminescence composite type enzyme mark detector, which is characterized in that the fluorescence
Detection device includes second light source, the second light guide module and fluorescence detector;
Second light guide module includes light guide seat, convex lens B and filter B;
The light guide seat is fixedly connected with the fixing seat, and a V-type guide lighting channel is equipped in the light guide seat;The V-type is led
Optical channel includes be connected the entering light channel to form V-structure and optical channel out;The light inlet in the entering light channel and it is described go out
The light-emitting window of optical channel is respectively positioned on the light guide seat upper surface;The entering light of the light-emitting window in the entering light channel and the optical channel out
Mouth is mutually screwed on, and is located at the light guide seat bottom surface, and is located at the top of the pallet;The second light source is fixedly arranged on downwards institute
At the light inlet for stating entering light channel;The convex lens B is fixedly arranged in the entering light channel, and the convex surface of the convex lens B is downward;
The filter B is fixedly arranged in the optical channel out;The fluorescence detector is fixedly arranged at the light-emitting window of optical channel out.
4. enzyme according to claim 3 exempts from fluorogenic chemiluminescence composite type enzyme mark detector, which is characterized in that the convex lens
The center of mirror B is located on the light direction of the second light source and the central axes in the entering light channel;The centre bit of the filter B
In on the central axes of optical channel out.
5. enzyme according to claim 1 exempts from fluorogenic chemiluminescence composite type enzyme mark detector, which is characterized in that the chemistry
Luminescence detection apparatus includes:
Photomultiplier tube;The photomultiplier tube is vertically installed on the top in the seal casinghousing and being located at the pallet;Institute
The lower end for stating photomultiplier tube is incident window, and upper end is anode tap;
Photon counter;The photon counter is connected with the upper end of the photomultiplier tube;
Detect headgear;The movable lower end for being sheathed on the photomultiplier tube of the detection headgear;
Lifting device;The lifting device is connected with the detection headgear, to drive the detection headgear in the photoelectricity times
The lower end for increasing pipe slides up and down.
6. enzyme according to claim 5 exempts from fluorogenic chemiluminescence composite type enzyme mark detector, which is characterized in that the lifting
Device includes:
Fixed plate;The fixed plate is horizontal to be installed on the hanging plate;The photomultiplier tube is installed on the fixed plate
Lower section;
Elevating lever, activity is worn in the fixed plate elevating lever in the vertical direction, the detection headgear and the elevating lever
Lower end connection;
Driving device, the driving device are connected with the upper end of the elevating lever, to drive the elevating lever vertically to move,
And then the detection headgear is driven to move up and down in the lower end of the photomultiplier tube by the elevating lever.
7. enzyme according to claim 6 exempts from fluorogenic chemiluminescence composite type enzyme mark detector, which is characterized in that the driving
Device includes:
Driving motor A;The driving motor A is installed on the upper surface of the fixed plate and connect with the master controller signal,
And one eccentric wheel assembly of output axis connection of the driving motor A;The upper end of the elevating lever connects a linkage board, the bias
The lower surface of wheel assembly and the linkage board offsets, with by the eccentric motion of the eccentric wheel assembly drive the linkage board to
Upper movement;
Spring, the spring pocket be set to the elevating lever on, and the spring be compressive state, the upper end of the spring with it is described
The lower surface of fixed plate offsets, and the upper end of the spring offsets with the detection headgear.
8. enzyme according to claim 7 exempts from fluorogenic chemiluminescence composite type enzyme mark detector, which is characterized in that the bias
Two symmetrically arranged magnet are installed, the eccentric wheel assembly side is equipped with one and connect with the master controller signal on wheel assembly
Hall sensor;
When one of two magnet are opposite with the Hall sensor, the Hall sensor generates inductive signal, the master
Controller judges the position of the detection headgear according to the inductive signal.
9. enzyme according to claim 1 exempts from fluorogenic chemiluminescence composite type enzyme mark detector, which is characterized in that its feature exists
In the movement mechanism includes:
Sliding rail;There are two the sliding rail is set, two sliding rails are set to the inner bottom surface of the seal casinghousing in transverse direction, and
The two sides of the corresponding inner bottom surface for being located at the seal casinghousing;
Sliding seat;There are two the sliding seat is set, two sliding seats are oppositely arranged, and corresponding slidable solid in transverse direction
On two sliding rails;
Grip block;The grip block is fixedly arranged on a wherein sliding seat side;
Driving motor B;The driving motor B be set to along the longitudinal direction the seal casinghousing inner bottom surface and with the master controller
Signal connection, and it is located at the grip block side;
Driving wheel;The driving wheel is fixedly arranged on the output shaft of the driving motor B;
Driven wheel;The driven wheel is set to the inner bottom surface of the seal casinghousing, and setting parallel with the driving wheel, and institute
State the equal length of the spacing and the sliding rail between driven wheel and the driving wheel;
Driving wheel band;The driving wheel band set is fixed on the driving wheel and the driven wheel, and the driving wheel band is clamped on
On the grip block;
Driving motor C;The driving motor C be fixedly arranged on a wherein sliding seat along the longitudinal direction and with the master controller
Signal connection;
Screw rod;One end of the screw rod is fixedly connected with the output shaft of the driving motor C, and the other end can be rotated along the longitudinal direction
Be installed on another sliding seat;
Guide rod;The guide rod is fixed on along the longitudinal direction between two sliding seats;
Feed screw nut;The feed screw nut is threadedly engaged on the screw rod;
Sliding block;The sliding block is fixedly arranged on the feed screw nut, and is offered on the sliding block so that the guide rod passed through
Pilot hole;
One end of the pallet is fixedly connected on the sliding block.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201721867113.7U CN208297531U (en) | 2017-12-26 | 2017-12-26 | Enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201721867113.7U CN208297531U (en) | 2017-12-26 | 2017-12-26 | Enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector |
Publications (1)
Publication Number | Publication Date |
---|---|
CN208297531U true CN208297531U (en) | 2018-12-28 |
Family
ID=64696959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201721867113.7U Active CN208297531U (en) | 2017-12-26 | 2017-12-26 | Enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN208297531U (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110133245A (en) * | 2019-05-24 | 2019-08-16 | 京东方科技集团股份有限公司 | A kind of detection device and detection method, relevant apparatus of enzyme linked immunological test board |
CN113552337A (en) * | 2021-07-19 | 2021-10-26 | 中山大学 | Full-spectrum high-efficiency microplate reader system |
-
2017
- 2017-12-26 CN CN201721867113.7U patent/CN208297531U/en active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110133245A (en) * | 2019-05-24 | 2019-08-16 | 京东方科技集团股份有限公司 | A kind of detection device and detection method, relevant apparatus of enzyme linked immunological test board |
CN113552337A (en) * | 2021-07-19 | 2021-10-26 | 中山大学 | Full-spectrum high-efficiency microplate reader system |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN202057579U (en) | Optical system capable of on-line detecting internal quality of fruits | |
CN208297531U (en) | Enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector | |
KR101505844B1 (en) | Multi-mode automatic optical measuring apparatus | |
CN205620308U (en) | Automatic check out test set in succession of biochip | |
CN209673807U (en) | A kind of Portable fluorescence immunity analysis instrument | |
CN105866452A (en) | Multi-channel dry type immunofluorescence detector | |
CN108562747A (en) | Enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector | |
CN218865757U (en) | Solution concentration measuring instrument based on spectrophotometry | |
JPS6344762Y2 (en) | ||
CN205808924U (en) | A kind of near infrared spectrum fruit quality on-line detecting system of automatic placement reference | |
KR20100082212A (en) | Method for measuring concentration of component in biochemical sample and for presuming reliability of test result | |
JPH0619321B2 (en) | Absorbance measuring device for microplate | |
CN104677845A (en) | Agricultural product tissue optical property automatic detection device based on integrating sphere | |
CN110057787B (en) | Free silica detector of dust | |
CN107817226B (en) | Three-dimensional automatic petroleum fluorescence analyzer | |
CN104502828B (en) | A kind of flip LED chips online test method | |
CN104502070B (en) | A kind of flip LED chips on-line checking receives optical tests component | |
CN201788147U (en) | Optical-fiber probe type soil nutrient tester | |
CN209946166U (en) | Novel eight-channel enzyme-labeled reading instrument | |
CN211318188U (en) | Optical detection system and sample analyzer | |
KR20160139820A (en) | Optical Measuring Apparatus | |
CN208295604U (en) | Exempt from the combined light source of analytical equipment for enzyme | |
CN109374555B (en) | Double-runner type physical and chemical detection system | |
KR101282159B1 (en) | Test Apparatus | |
CN106501198A (en) | Fully-automatic multi-channel absorbance measuring instrument |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
GR01 | Patent grant | ||
GR01 | Patent grant |