CN207221947U - A kind of segmented micro-fluidic chip temperature regulating device - Google Patents
A kind of segmented micro-fluidic chip temperature regulating device Download PDFInfo
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- CN207221947U CN207221947U CN201720151158.8U CN201720151158U CN207221947U CN 207221947 U CN207221947 U CN 207221947U CN 201720151158 U CN201720151158 U CN 201720151158U CN 207221947 U CN207221947 U CN 207221947U
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Abstract
The utility model discloses a kind of segmented micro-fluidic chip temperature regulating device, including temperature control platform, intelligent temperature regulator and constant temperature circulator, the temperature control platform ecto-entad is made of the upward semiconductor chilling plate of shell, cold plate and hot plate, huyashi-chuuka (cold chinese-style noodles) and heater, radiator, metal catheter, there is temperature meter in cold-hot plate.The present apparatus has used high-performance micro semiconductor chilling plate and ceramic heating flake, reduces device volume, improves the practicality of temperature control platform；The temperature data for the hot plate cold plate that the present apparatus is collected using commercial temperature controller according to platinum electrode, by controlling the operation and stopping of semiconductor chilling plate and ceramic heating flake, realizes High Precision Automatic temperature control；Using constant temperature circulator, the temperature range of circulating liquid is set to be maintained at 60 DEG C 50 DEG C, meet the cooling requirements of the present apparatus, reduce use cost, realize that biological PCR, drop and capsule in micro-fluidic chip solidify the experiment such as thawing, crystal-phase transformation, materials synthesis suitable for temperature control micro-fluidic chip.
Description
Technical field
The utility model belongs to thermoelectric applied technical field, is filled more particularly to a kind of segmented micro-fluidic chip temperature control
Put.
Background technology
As the continuous development of microflow control technique is with ripe, more and more various biological and chemical experimental examples such as numeral
PCR, cell culture, materials synthesis, drug screening etc. will all be realized in a slight micro-fluidic chip.Usually these experiments
It is required for smoothly reacting at a certain temperature, this temperature range is generally at -40-100 DEG C.
At present, the above-mentioned experiment in micro-fluidic chip is all by using high-low temperature chamber or temperature cycling test mostly
Case carries out temperature control to be tested, and not only temperature-controlled precision is relatively low for these equipment, and operating temperature range is also smaller, and volume and work(
Consumption is all very big.
Utility model content
The utility model is solution problems of the prior art, there is provided a kind of temperature control equipment, present apparatus tool
There is the characteristics of temperature-controlled precision is high, operating temperature range is big, good heat dissipation effect, small energy consumption.
The purpose of this utility model is achieved through the following technical solutions：
A kind of segmented micro-fluidic chip temperature regulating device, it is characterised in that：Including temperature control platform, intelligent temperature regulator,
And constant-temperature circulating device, the temperature control platform ecto-entad by the upward semiconductor chilling plate of shell, cold plate and hot plate, huyashi-chuuka (cold chinese-style noodles),
Heater, radiator, metal catheter are formed, and have temperature meter in cold-hot plate.Intelligent temperature regulator and heater and the temperature difference
Electric refrigerating assembly is connected；The water outlet of water jacket, going out on constant temperature circulator in import connection temperature control platform on constant temperature circulator
The water inlet of water jacket in mouth of a river connection temperature control platform.
Further, the temperature control platform be fixed on using 3D printing come out shell among, the cold plate of temperature control platform and
Hot plate is the copper structure of stepped ramp type, and the boss position of cold plate and hot plate is embedded in the square hole of shell upper, boss upper surface with
Case surface is in one plane；Hot and cold plate is be bonded using heat conductive silica gel with thermoelectric cooling module, and cold plate and hot plate side have
One hole, the axis in hole is parallel with cold plate upper surface, and the temperature meter is the PT100 platinum being placed in cold plate and hot plate lateral aperture
Electrode；Thermoelectric cooling module is by high performance micro semiconductor refrigerator (Ferrotec 9503/035/025M) structure
Into the huyashi-chuuka (cold chinese-style noodles) of thermoelectric cooling module, hot face are coated with heat-conducting silicone grease；The heater assembly is by ceramic heater structure
Into heater is linked together using heat conductive silica gel and hot plate；Radiator is copper stepped component, and there is U-shaped groove in inside
For installing coolant duct, shell side face corresponding position has water jacket water inlet and water jacket water outlet, and the constant temperature circulator is
The HX-1050 type constant temperature circulators being placed in outside babinet.
Further, the cooling piece and heating plate are micro semiconductor cooling piece and miniature ceramic heating flake.
Further, the shell forms the size and number that can change cold plate and hot plate as needed for 3D printing.
Further, the temperature control platform is made of multiple independent cold plates and hot plate, each cold plate and hot plate temperature
Independent control is independent of each other.
Preferably, the conduit is red copper conduit.
The utility model has the advantages and positive effects of：
1st, using the high performance micro semiconductor refrigerator (Ferrotec 9503/035/025M) of import, it is ensured that this dress
Put with enough refrigeration depth and refrigeration speed；Refrigerated medium hot arc is divided into seven sections, and refrigeration section is all by an independent control
The semiconductor chilling plate of system carrys out regulating and controlling temperature, and heating area is by an independent heater come regulating and controlling temperature, the temperature of different sections
Control that can be independent；High Precision Automatic temperature control, temperature control are realized by Tempco TEC-220 program-type intelligent temperature regulators
Scope and precision reach -40 DEG C -100 DEG C (± 0.2 DEG C), and the minisize refrigeration piece used and hot meet micro-fluidic chip volume
The characteristics of small, can substantially reduce the number experiment energy consumption, reduce use cost, whole temperature measuring area uniform distribution of temperature field, stabilization.
2nd, using the external HX-1050 type constant temperature circulators with automatic pid control function, by circulating liquid by the temperature difference
The waste heat that the hot face of electric refrigerating assembly produces is taken away, by automatic PID control, make circulating liquid temperature range be maintained at -10 DEG C -
50 DEG C, meet the cooling requirements of the present apparatus.
3rd, using Tempco TEC-220 program-type intelligent temperature regulators, realize that human-computer interaction uses, and and computer
Real-time communication, ensures temperature control accurately and reliably.
4th, the present apparatus suitable for micro-fluidic chip temperature control realize biological PCR, drop and capsule in micro-fluidic chip
Solidify the experiment such as thawing, crystal-phase transformation, materials synthesis.
Brief description of the drawings
Fig. 1 is temperature regulating device appearance schematic diagram；
Fig. 2 is temperature regulating device schematic front view in Fig. 1；
Fig. 3 is A-A schematic cross-sectional views in Fig. 2；
Embodiment
Below in conjunction with the accompanying drawings and the utility model is described in further detail by the way that example is embodied, and following embodiment is only
It is descriptive, is not limited, it is impossible to which the scope of protection of the utility model is limited with this.
Fig. 1 be refer to Fig. 3：From left to right successively by intelligent temperature regulator 1, temperature control platform, and constant-temperature circulating device
12 form segmented micro-fluidic chip temperature regulating device, have the com used with external connection of computer to connect in the intelligent temperature regulator
Mouth 4, the module 2 being connected with temperature meter 22, the module 3 being connected with heating plate and cooling piece 21, the temperature control platform is by outer
Inwardly by shell 8, cold plate 10 and hot plate 7,9,11, the upward semiconductor chilling plate 21 of huyashi-chuuka (cold chinese-style noodles) and heating plate, radiator 16, metal
Conduit 17,18 is formed, and has temperature meter 22 in cold-hot plate.Intelligent temperature regulator and heater and thermoelectric cooling module it
Between using copper conductor 5 be connected, be connected between intelligent temperature regulator and temperature meter using copper conductor 6；Constant temperature circulator 12
On import 14 be connected with the water outlet 18 of copper pipe in temperature control platform using rubber tube 13, the water outlet 15 on constant temperature circulator connects
Connect the water inlet 17 of copper pipe in temperature control platform.
Temperature control platform is fixed among the shell come out using 3D printing, and the cold plate and hot plate of temperature control platform are stepped ramp type copper
The boss position of matter structure, cold plate and hot plate is embedded in the square hole of shell upper, and boss upper surface is with case surface at one
In plane；Cold plate is be bonded using heat conductive silica gel with thermoelectric cooling module, and there are a hole in cold plate and hot plate side, the axis in hole with it is cold
Plate upper surface is parallel, and the temperature meter is the PT100 platinum electrodes being placed in cold plate and hot plate lateral aperture；Thermoelectric (al) cooling group
Part is made of a high performance micro semiconductor refrigerator (Ferrotec 9503/035/025M), difference electricity refrigerating assembly it is cold
Face, hot face are coated with heat-conducting silicone grease；Radiator is copper stepped component, and inside has U-shaped groove to be used for installing coolant
Pipeline, shell side face corresponding position have water jacket water inlet and water jacket water outlet, and the constant temperature circulator is the HX- being placed in outside babinet
1050 type constant temperature circulators.
Tempco TEC-220 program-types intelligent temperature regulators realize Tempco TEC-220 programs by RS232COM
The connection of type intelligent temperature regulator and host computer, completes real-time communication and data-transformation facility；Tempco TEC-220 programs
Type intelligent temperature regulator is connected directly with cooling piece and heater, works as electric power starting, Tempco TEC-220 program-types intelligence
Thermoregulator can ensure Ferrotec 9503/035/025M thermoelectric cooling modules and the power supply of heater normal DC, really
Protect the refrigeration demand of refrigerator and the demand for heat of heater；Tempco TEC-220 program-types intelligent temperature regulators with
PT100 platinum resistance terminals are connected, and are provided by PT100 platinum resistance for Tempco TEC-220 program-type intelligent temperature regulators
Resistance input parameter, realizes that temperature monitors in real time.
Temperature control
When Tempco TEC-220 program-type intelligent temperature regulators power on, Tempco TEC-220 program-types are intelligent
Thermoregulator receives the temperature feedback information from PT100 platinum resistance, passes through programme-control Ferrotec 9503/035/
The startup of 025M thermoelectric cooling modules and ceramic heater and stop working state, realize the temperature control requirement of temperature controller,
Meet -40 DEG C -100 DEG C, the requirement of temperature-controlled precision ± 0.2 DEG C.Tempco TEC-220 program-types intelligent temperature regulator ensures
The requirement of device heating-cooling speed, when setting speed exceedes system maximum parameter, system automatic time delay is according to maximum rate parameter
Heating and cooling.Can also as needed using segmented program set temperature control method, realize temperature monitoring, implementation procedure control and in real time
Human-machine operation, information mutual communication, ensures temperature control accurately and reliably.Tempco TEC-220 program-type intelligent temperature regulators possess PID
Self-setting function has the programmable operations such as cycling jump, operation, pause life, it can be achieved that the heating-cooling control of any slope
Order, it is allowed to change program at any time in program operation process.HX-1050 types constant temperature circulator radiates as external liquid SAPMAC method
Device, using circulating liquid as carrier, it is ensured that fluid homeostasis at the uniform velocity flows, there is provided the power of liquid-circulating heat radiation, by Ferrotec
The waste heat that the hot face of 9503/035/025M thermoelectric cooling modules produces is taken away, and circulating liquid temperature-control range is maintained at -10 DEG C -50
DEG C, fully meet high-low temperature tester radiating requirements.
The operation principle of the present apparatus：Sufficiently large refrigerating capacity is locally being produced using thermoelectric cooling module, is being realized enough
Big refrigeration depth and sufficiently fast refrigeration speed, heat hot plate using ceramic heating flake, realize the temperature control of hot plate
System, using Tempco TEC-220 program-types intelligent temperature regulators by collecting the feedback parameter of temperature meter, automatic control
On experiment porch processed in each hot plate and cold plate heating plate and cooling assembly operation and stopping, realizing each in operation temperature area
The High Precision Automatic temperature control of temperature.
Specific embodiment of the utility model is described above.It is to be appreciated that the utility model not office
It is limited to above-mentioned particular implementation, those skilled in the art can make various deformations or amendments within the scope of the claims,
This has no effect on the substantive content of the utility model.
Claims (5)
- A kind of 1. segmented micro-fluidic chip temperature regulating device, it is characterised in that：Including temperature control platform, intelligent temperature regulator and Constant-temperature circulating device, the temperature control platform ecto-entad by the upward semiconductor chilling plate of shell, cold plate and hot plate, huyashi-chuuka (cold chinese-style noodles), plus Hot device, radiator, metal catheter are formed, and have temperature meter, intelligent temperature regulator and heater and temperature in cold plate and hot plate Poor electricity refrigerating assembly is connected；The water outlet of water jacket in import connection temperature control platform on constant temperature circulator, on constant temperature circulator The water inlet of water jacket in water outlet connection temperature control platform.
- 2. segmented micro-fluidic chip temperature regulating device according to claim 1, it is characterised in that：The temperature control platform is fixed Among the shell come out using 3D printing, the cold plate and hot plate of temperature control platform are the copper structure of stepped ramp type, cold plate and hot plate Boss position is embedded in the square hole of shell upper, and boss upper surface and case surface are in one plane；Cold plate and thermoelectric Refrigerating assembly is bonded using heat conductive silica gel, and hot plate is be bonded using heat conductive silica gel with heater assembly, and cold plate and hot plate side have one Hole, the axis in hole is parallel with cold plate upper surface, and the temperature meter is the PT100 platinum electricity being placed in cold plate and hot plate lateral aperture Pole；Thermoelectric cooling module is made of a high performance micro semiconductor refrigerator Ferrotec9503/035/025M, difference electricity The huyashi-chuuka (cold chinese-style noodles) of refrigerating assembly, hot face are coated with heat-conducting silicone grease；The heater assembly is made of ceramic heater；Radiator is Copper stepped component, inside have U-shaped groove to be used for installing coolant duct, and shell side face corresponding position has water jacket water inlet With water jacket water outlet, the constant temperature circulator is the HX-1050 type constant temperature circulators being placed in outside babinet.
- 3. segmented micro-fluidic chip temperature regulating device according to claim 1 or 2, it is characterised in that：The cooling piece and Heater is micro semiconductor cooling piece and miniature ceramic heating flake.
- 4. segmented micro-fluidic chip temperature regulating device according to claim 1 or 2, it is characterised in that：The temperature control platform It is made of multiple independent cold plates and hot plate, each cold plate and hot plate temperature independent control is independent of each other.
- 5. segmented micro-fluidic chip temperature regulating device according to claim 1 or 2, it is characterised in that：The conduit is purple Copper conductor tube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720151158.8U CN207221947U (en) | 2017-02-20 | 2017-02-20 | A kind of segmented micro-fluidic chip temperature regulating device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720151158.8U CN207221947U (en) | 2017-02-20 | 2017-02-20 | A kind of segmented micro-fluidic chip temperature regulating device |
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| Publication Number | Publication Date |
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| CN207221947U true CN207221947U (en) | 2018-04-13 |
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| CN201720151158.8U Expired - Fee Related CN207221947U (en) | 2017-02-20 | 2017-02-20 | A kind of segmented micro-fluidic chip temperature regulating device |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106861779A (en) * | 2017-02-20 | 2017-06-20 | 广东工业大学 | A kind of segmented micro-fluidic chip temperature regulating device |
| CN110554651A (en) * | 2019-09-19 | 2019-12-10 | 哈尔滨工业大学 | Private Internet of things system for measuring and controlling temperature of microfluidic chip |
| CN111949055A (en) * | 2020-08-03 | 2020-11-17 | 中国科学院长春光学精密机械与物理研究所 | Independent temperature control system and method for microfluidic culture chip |
| CN113960446A (en) * | 2021-10-10 | 2022-01-21 | 北京工业大学 | Temperature-controllable SiC chip power cycle experimental device |
-
2017
- 2017-02-20 CN CN201720151158.8U patent/CN207221947U/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106861779A (en) * | 2017-02-20 | 2017-06-20 | 广东工业大学 | A kind of segmented micro-fluidic chip temperature regulating device |
| CN110554651A (en) * | 2019-09-19 | 2019-12-10 | 哈尔滨工业大学 | Private Internet of things system for measuring and controlling temperature of microfluidic chip |
| CN110554651B (en) * | 2019-09-19 | 2021-07-30 | 哈尔滨工业大学 | Private Internet of things system for measuring and controlling temperature of microfluidic chip |
| CN111949055A (en) * | 2020-08-03 | 2020-11-17 | 中国科学院长春光学精密机械与物理研究所 | Independent temperature control system and method for microfluidic culture chip |
| CN113960446A (en) * | 2021-10-10 | 2022-01-21 | 北京工业大学 | Temperature-controllable SiC chip power cycle experimental device |
| CN113960446B (en) * | 2021-10-10 | 2023-10-10 | 北京工业大学 | SiC chip power cycle experimental apparatus of controllable temperature |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180413 |
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| CF01 | Termination of patent right due to non-payment of annual fee |