CN206725325U - Embedded box - Google Patents
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- CN206725325U CN206725325U CN201720561494.XU CN201720561494U CN206725325U CN 206725325 U CN206725325 U CN 206725325U CN 201720561494 U CN201720561494 U CN 201720561494U CN 206725325 U CN206725325 U CN 206725325U
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- embedded box
- lid
- skirt section
- bottom plate
- biological tissue
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Abstract
The utility model provides a kind of embedded box, it is related to biological tissue embedding technical field, the embedded box includes bottom plate, the skirt section to be formed and the lid being connected with skirt section is upwardly extended along bottom edge, lid and bottom plate are equipped with the window for biological tissue dewatering, skirt section is enclosed with bottom plate is connected into an accommodating chamber connected with window, and the outer surface of lid and/or the outer surface of bottom plate are equipped with multiple projections.The utility model alleviates embedded box placement superposed on one another and close adjacent in tissue dewatering processing procedure in the prior art, causes heat in tissue dewatering processing procedure to be unable to the transmission of uniform high-efficiency, costs and poor dehydration results, the technical problem of dewatering time length be present.
Description
Technical field
It the utility model is related to biological tissue embedding technical field, more particularly to a kind of embedded box.
Background technology
Pathology department is the important section office in hospital, is responsible for the vital tasks such as pathological diagnosis research, generally with biological tissue or
The mode of cytoscopy is diagnosed and studied to the disease of patient, helps medical worker preferably to grasp treatment relevant disease
Method, therapeutic treatment level is improved, be a kind of reliable, accurate diagnostic method.In pathological study, it will generally carry out at section
Biological tissue after reason is put into embedded box, and there are embedded box embedded material powder or other block structures to provide performance branch
Support or the effect of chemoproection, can strengthen the processing quality to microorganism or cell tissue, avoid stripping and slicing from repairing.
Although embedded box of the prior art has above-mentioned advantage, in tissue dewatering processing procedure, a dehydration
Multiple embedded boxes are generally placed with basket, due to embedded box placement superposed on one another, and it is close adjacent, therefore cause at biological tissue
Dehydrating agent can not be transmitted efficiently during reason, costs and poor dehydration results, the technical problem of dewatering time length be present.
Utility model content
The purpose of this utility model is to provide a kind of embedded box, with alleviate in the prior art embedded box in tissue dewatering
Placement superposed on one another and close adjacent in processing procedure, dehydrating agent can not be transmitted efficiently during causing tissue processing,
Costs and poor dehydration results, the technical problem of dewatering time length be present.
A kind of embedded box provided by the utility model, including bottom plate, along the bottom edge upwardly extend the skirt section to be formed
With the lid affixed with the skirt section；
The lid and the bottom plate are equipped with the window for biological tissue dewatering, and the skirt section is enclosed with the bottom plate to be connect
The outer surface of window connection accommodating chamber described in Cheng Yiyu, the outer surface of the lid and the bottom plate is equipped with multiple projections.
Further, the outer skirt surface is provided with the Quick Response Code and/or numbering plate for being used for marking biological tissue.
Further, the data board for marking biological tissue is additionally provided with the outer skirt surface
Further, the lid be provided be used to opening and closing lid break hand.
Further, the skirt section is hinged with the lid, and the skirt section is provided with neck, the inner surface of the lid
Provided with the buckle with the neck clamping.
Further, the top of the skirt section opposing end surface is provided with chute, the chute and the lid clamping.
Further, the window is the slot in matrix arrangement.
Further, the window is the circular port in matrix arrangement.
Further, the embedded box is polythene material.
The beneficial effects of the utility model are：
In the utility model, the embedded box includes bottom plate, skirt section and the lid affixed with skirt section, and lid and bottom plate are all provided with
There is the window for biological tissue dewatering, skirt section is enclosed with bottom plate is connected into an accommodating chamber connected with window.In use, life will be filled
The embedded box of thing histotomy puts dehydration basket into and carries out dewater treatment, and embedded box adjacent to each other is when stacking, due to bottom plate
Outer surface and/or the outer surface of lid set multiple projections, therefore the lid for the embedded box being located below and face disposed thereon
Form the gap of certain altitude between the bottom plate of embedded box, the gap between adjacent embedded box can improve heat dehydrating agent it
Between transmission, avoid because the superposition of embedded box causes the problem of dehydrating agent transmits between biological tissue.
Meanwhile the gap between adjacent embedded box also add the contact area between embedded box and dehydrating agent so that bag
Bury that contact area between the biological tissue in box and dehydrating agent is bigger, accelerate the permeability of tissue processing dehydration,
And then shorten the processing time that the embedded box carries out dehydration in dehydration basket, and it is ingenious in design, it is rational in infrastructure, there is practicality
The characteristics of strong and feature is good.
Brief description of the drawings
, below will be right in order to illustrate more clearly of the utility model embodiment or technical scheme of the prior art
The required accompanying drawing used is briefly described in embodiment or description of the prior art, it should be apparent that, describe below
In accompanying drawing be some embodiments of the present utility model, for those of ordinary skill in the art, do not paying creativeness
On the premise of work, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is the structural representation for the embedded box that the utility model embodiment one provides；
Fig. 2 is the structural representation with raised lid in Fig. 1；
Fig. 3 is the structural representation with heaving floor in Fig. 1；
Fig. 4 is the structural representation for another embedded box that the utility model embodiment one provides.
Icon：1- bottom plates；2- skirt sections；3- lids；4- accommodating chambers；5- chutes；11- windows；12- is raised；31- buckles；32-
Break hand.
Embodiment
The technical solution of the utility model is clearly and completely described below in conjunction with accompanying drawing, it is clear that described
Embodiment is the utility model part of the embodiment, rather than whole embodiments.Based on the embodiment in the utility model, sheet
The every other embodiment that field those of ordinary skill is obtained under the premise of creative work is not made, belongs to this practicality
Novel protected scope.
, it is necessary to explanation in description of the present utility model, term " " center ", " on ", " under ", it is "left", "right", " perpendicular
Directly ", the orientation of the instruction such as " level ", " interior ", " outer " or position relationship are based on orientation shown in the drawings or position relationship, are only
Described for the ease of description the utility model and simplifying, rather than instruction or imply signified device or element must have it is specific
Orientation, with specific azimuth configuration and operation, therefore it is not intended that to limitation of the present utility model.In addition, term " the
One ", " second ", " the 3rd " are only used for describing purpose, and it is not intended that instruction or hint relative importance.
, it is necessary to which explanation, unless otherwise clearly defined and limited, term " are pacified in description of the present utility model
Dress ", " connected ", " connection " should be interpreted broadly, for example, it may be fixedly connected or be detachably connected, or integratedly
Connection；Can be mechanical connection or electrical connection；Can be joined directly together, can also be indirectly connected by intermediary,
It can be the connection of two element internals.For the ordinary skill in the art, above-mentioned art can be understood with concrete condition
Concrete meaning of the language in the utility model.
Embodiment
As shown in Figure 1, Figure 2 and Figure 3, the present embodiment provides a kind of embedded box, including bottom plate 1, prolongs upwards along the edge of bottom plate 1
Stretch the skirt section 2 to be formed and the lid 3 affixed with skirt section 2.
Lid 3 and bottom plate 1 are equipped with the window 11 for biological tissue section dehydration, skirt section 2 and bottom plate 1 enclose be connected into one with
Window 11 connects accommodating chamber 4, and the outer surface of lid 3 and the outer surface of bottom plate 1 are equipped with multiple raised 12.
In the present embodiment, the embedded box includes bottom plate 1, skirt section 2 and the lid 3 affixed with skirt section 2, lid 3 and bottom plate 1
The window 11 for biological tissue section dehydration is equipped with, skirt section 2 is enclosed with bottom plate 1 is connected into an accommodating chamber 4 connected with window 11.
In use, putting the embedded box for filling biological tissue section into dehydration basket carries out dewater treatment, embedded box adjacent to each other is folded
When putting, because the outer surface of bottom plate 1 and/or the outer surface of lid 3 set multiple raised 12, therefore the embedded box being located below
The gap of certain altitude, the gap energy between adjacent embedded box are formed between lid 3 and the bottom plate 1 of the embedded box in face disposed thereon
Transmission of the heat between dehydrating agent is enough improved, is avoided because the superposition of embedded box causes heat transfer between biological tissue section
The problem of.
Meanwhile the gap between adjacent embedded box also add the contact area between embedded box and dehydrating agent so that bag
Bury that contact area between the biological tissue in box and dehydrating agent is bigger, accelerate the permeability of tissue processing dehydration,
And then shorten the processing time that the embedded box carries out dehydration in dehydration basket, and it is ingenious in design, it is rational in infrastructure, there is practicality
The characteristics of strong and feature is good.
In the present embodiment, the step of biological tissue section embeds is as follows；
1st, experimenter carries out section materials using fetching knife to biological tissue section.
2nd, the biologic slice tissue of selection is fixed processing using certain density formalin fixer, biological group
The decomposition of histocyte self-dissolving, corruption and intracellular enzyme to protein can be prevented by knitting the fixing process of section, be made thin
The various composition of intracellular such as protein, fat, carbohydrate or enzyme are changed into insoluble substance, to keep biological tissue to cut
The original structure of piece.Meanwhile biological tissue section fix after be in certain hardening state, add tissue toughness and not variable
Shape, the biological tissue section of postorder is facilitated to handle being smoothed out for work.
3rd, washing process is carried out to the biological tissue section after fixing process, washing process can prevent biological tissue section
Flake, and improve and make it that the color of biological tissue section is more bright-coloured.
4th, the biological tissue section after above-mentioned processing is put into embedded box, chooses the alcohol of various concentrations to biological group
Knit section and carry out dewater treatment, dewater treatment enables to embedding medium smoothly to enter in biological tissue section, improves whole biology
The success rate of histotomy processing；After biological tissue section dewater treatment, the transparent place of biological tissue section is carried out using dimethylbenzene
Reason, dimethylbenzene is that one kind can be mutually dissolved with dehydrating agent, the media material that and can mixes with paraffin.
5th, the biological tissue section after transparent processing is put into the paraffin of fusing and impregnated, and by biological group after waxdip
Knit section to be again placed in the paraffin of melting state, wait paraffin into wax stone.
In the present embodiment, more moisture is contained after fixation and flushing in biological tissue in biological tissue, using de-
Aqua cements out the moisture in tissue, in favor of the infiltration of organic solvent.
In the present embodiment, when carrying out biological tissue embedding processing, aid in treatment can be carried out using embedding machine.Embedding machine
After use, table top, groove and grafting wax box are cleared up immediately, are understood that the wax on embedding machine is had a rest and frost, are kept machine clean
Neatly.Meanwhile each two weeks or one month will be to embedding machine dewaxing groove and screen pack do corresponding cleaning sterilization.
Wherein, the embedding machine includes the slicing device for block sections, and slicing device includes the cutting knife of roller type, driving
The cutting knife rolled round and the wax stone fixed station positioned at section lower section that cutting knife rotates.
In the present embodiment, the wax stone of slice is removed from freezing stage and be positioned on wax stone fixed station, and cause wax
Block plane is parallel with cutting knife blade, shakes cutting knife rolled round, slightly cuts wax stone to exposure largest face；Feed distance is adjusted, to trimming
Wax stone cut again, left hand is shaken cutting knife rolled round and uniform rotation, wax stone is cut using the stable wax stone of hairbrush, the right hand
Into preferable section, it is fitted to each other by the cutting knife three of wax stone fixed station, cutting knife rolled round and roller type, can be quick and convenient right
Wax stone carries out slicing treatment, simple to operate, cuts convenient convenience, has the characteristics of practical and feature is good.
In the present embodiment, during wax stone is cut, left hand takes hairbrush to tilt the section cut, and the right hand picks up section by tweezers
And be put into certain density alcohol liquid, experimenter is moved to section in plate stretching cistern with clean glass plate, then is passed through
Tweezers will be cut into slices and be flattened.
In the present embodiment, should be noted that when wax stone is cut it is following some；
1st, the sharp and clean of cutting knife is kept.
2nd, slide must be clean, bright.
3rd, the slice thickness of wax stone should be maintained at 3-5um, and cut into slices be uniformly, without tool marks, chatter mark, fold, open
Split, defect, absent-mindedness etc..
4th, after often cutting a wax stone, it should the water surface is cleared up, the fragment of tissue of other cases must not be left, in order to avoid pollution.
In the present embodiment, the outer surface of skirt section 2 of the embedded box is provided with the Quick Response Code for being used for marking biological tissue section.
Put into the embedded box for filling biological tissue section before dehydration basket carries out dewater treatment, staff can be by with can
The electronic equipment surface sweeping of identification Quick Response Code is located at the Quick Response Code on the outer surface of skirt section 2, and each fill is needed to carry out dewater treatment
Embedded box carry out detailed information record, the information after record is stored in the electronic equipments such as computer accordingly；When filling life
After dehydration basket progress dewater treatment of the embedded box of thing histotomy putting into terminates, operating personnel can pass through each embedded box of surface sweeping
On Quick Response Code obtain the information of the biological tissue section on the embedded box, prevent from carrying out the embedded box quantity mistake of dewater treatment
It is more, cause experimenter misregistration occur when carrying out embedded box arrangement, cause assay mistake be in the presence of, enter one
The characteristics of step improves the practicality, feature and security of the embedded box, meanwhile, also improve embedded box experiment process process
In efficiency.
In the present embodiment, the record for marking biological tissue section is additionally provided with the outer surface of skirt section 2 of the embedded box
Plate.Before the embedded box for filling biological tissue section puts dehydration basket progress dewater treatment into, staff can also be by each
The details for needing to carry out the embedded box of dewater treatment are recorded on data board by marking pen；When filling biological tissue section
Embedded box put dehydration basket into and carry out after dewater treatment terminates, operating personnel can pass through the Quick Response Code on each embedded box of surface sweeping
To obtain the information of the biological tissue section on the embedded box, by the relevant information obtained by scanning on Quick Response Code and data board
On information be compared, compare Quick Response Code and whether information that data board is recorded consistent, identical then information is errorless, otherwise believes
Cease it is wrong, further prevent carry out dewater treatment embedded box quantity it is excessive, cause experimenter when carrying out embedded box arrangement
There is misregistration, cause assay mistake be in the presence of, further increase the practicality of the embedded box, feature and
The characteristics of security, meanwhile, also improve the efficiency during embedded box experiment process.
As depicted in figs. 1 and 2, in the present embodiment, lid 3 be provided be used to opening and closing lid 3 break hand 32.When filling
After the embedded box of biological tissue section carries out dewater treatment, experimenter takes out the embedded box in dehydration basket, holds skirt on the other hand
Portion 2, the other hand by will break hand 32 by lid 3 open and by box biologic slice tissue carry out FFPE processing.
As shown in figure 1, wherein, in the present embodiment, skirt section 2 is be hinged with lid 3, and skirt section 2 is provided with neck, lid 3
Inner surface be provided with buckle 31 with neck clamping.When biological tissue section carries out dewater treatment, experimenter will carry out phase
The biological tissue section that should be handled is placed into the accommodating chamber 4 of embedded box, wherein, the buckle 31 that the inner surface of lid 3 is provided with, skirt section
2 are provided with neck, enable to lid 3 tightly to seal up in skirt section 2 by buckle 31 and neck clamping, prevent from cutting in biological tissue
When piece carries out dewater treatment in dehydration basket, biological tissue section departs from embedded box, reasonable in design, simple in construction, further carries
The high practicality and feature of the embedded box.
As shown in figure 4, wherein, in the present embodiment, the top of the opposing end surface of skirt section 2 is provided with chute 5, chute 5 and lid 3
Clamping.After the embedded box for filling biological tissue section carries out dewater treatment, experimenter takes out the embedded box in dehydration basket,
Experimenter takes out the embedded box in dehydration basket, holds skirt section 2 on the other hand, because lid 3 and chute 5 are slidably connected, tests people
Another hand of member can skid off lid 3 out of chute 5, simple and convenient, easily open lid 3.
In the present embodiment, the upper surface of lid 3 can be provided with a depressed part, open the lid 3 when, experimenter's
Hand can be embedded in the depressed part, and depressed part can increase the frictional force between experimenter's finger and lid 3, more easily
Lid 3 is opened and the biologic slice tissue in box is subjected to FFPE processing.Meanwhile it can be set in the upper surface of lid 3
There is a depressed part, experimenter's one-handed performance can also be easy to open lid 3, further increase the practicality of the embedded box
Property and feature.
As shown in Figure 1, Figure 2, Figure 3 and Figure 4, in the present embodiment, window 11 is the rectangular opening in matrix arrangement.As general
The embedded box for filling biological tissue section is put into dehydration basket, and the window 11 in the rectangular opening of matrix arrangement can increase biology
The contact area of histotomy and dehydrating agent so that embedded box contacts more with dehydrated reagent, uniformly shortens biological tissue and cuts
The time of piece dehydration, improve the efficiency of biological tissue section dehydration.Meanwhile can also in the window 11 of the rectangular opening of matrix arrangement
Enough so that biological tissue section is in dehydration process, heat is capable of the transmission of uniform high-efficiency, and it is de- to improve biotic component section
Dehydrating effect in water treatment procedure.
In the present embodiment, window 11 can also be the circular port in matrix arrangement.The window 11 of circular port with it is above-mentioned
Dominant Facies possessed by the window 11 of rectangular opening are same, have clearly stated, will not be repeated here above.
Specifically, in the present embodiment, embedded box is polythene material.Polyethylene has odorless, nontoxic chemical characteristic,
And it is low temperature resistant, chemical stability is good, meanwhile, polyethylene also has good corrosion resistance, insulating properties and water proofing property.
In the present embodiment, the embedded box can be injection molding part, and injection molding has and can mass produce, process
The characteristics of cycle is short, simple to operate and manufacturing cost is low.
Finally it should be noted that：Various embodiments above is only to illustrate the technical solution of the utility model, rather than it is limited
System；Although the utility model is described in detail with reference to foregoing embodiments, one of ordinary skill in the art should
Understand：It can still modify to the technical scheme described in foregoing embodiments, either to which part or whole
Technical characteristic carries out equivalent substitution；And these modifications or replacement, the essence of appropriate technical solution is departed from this practicality newly
The scope of each embodiment technical scheme of type.
Claims (9)
1. a kind of embedded box, it is characterised in that upwardly extend the skirt section to be formed including bottom plate (1), along the bottom plate (1) edge
(2) lid (3) and with the skirt section (2) being connected；
The lid (3) and the bottom plate (1) are equipped with the window (11) for biological tissue dewatering, the skirt section (2) and institute
State bottom plate (1) and enclose and be connected into an accommodating chamber (4) connected with the window (11), the outer surface and/or the bottom of the lid (3)
The outer surface of plate (1) is equipped with multiple raised (12).
2. embedded box according to claim 1, it is characterised in that skirt section (2) outer surface, which is provided with, to be used to mark life
The Quick Response Code of thing tissue.
3. embedded box according to claim 2, it is characterised in that be additionally provided with skirt section (2) outer surface for marking
The data board of biological tissue.
4. embedded box according to claim 3, it is characterised in that the skirt section (2) is be hinged with the lid (3), and institute
State skirt section (2) and be provided with neck, the inner surface of the lid (3) is provided with buckle (31), the buckle (31) and the neck card
Connect.
5. embedded box according to claim 4, it is characterised in that, the lid (3), which is provided with, to be used to open and close lid (3)
Break hand (32).
6. embedded box according to claim 3, it is characterised in that the top of skirt section (2) opposing end surface is provided with chute
(5), the chute (5) is slidably connected with the lid (3).
7. according to the embedded box described in claim any one of 1-6, it is characterised in that the window (11) is in matrix arrangement
Slot.
8. according to the embedded box described in claim any one of 1-6, it is characterised in that the window (11) is in matrix arrangement
Circular port.
9. embedded box according to claim 8, it is characterised in that the embedded box is polythene material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720561494.XU CN206725325U (en) | 2017-05-19 | 2017-05-19 | Embedded box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720561494.XU CN206725325U (en) | 2017-05-19 | 2017-05-19 | Embedded box |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206725325U true CN206725325U (en) | 2017-12-08 |
Family
ID=60513923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720561494.XU Active CN206725325U (en) | 2017-05-19 | 2017-05-19 | Embedded box |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206725325U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113233143A (en) * | 2021-04-22 | 2021-08-10 | 川北医学院 | Device for marking histology embedding box |
| CN113432957A (en) * | 2021-06-28 | 2021-09-24 | 广州中医药大学第一附属医院 | Embedding box |
| WO2023082080A1 (en) * | 2021-11-10 | 2023-05-19 | Leica Biosystems Nussloch Gmbh | Cassette and embedding method using same |
-
2017
- 2017-05-19 CN CN201720561494.XU patent/CN206725325U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113233143A (en) * | 2021-04-22 | 2021-08-10 | 川北医学院 | Device for marking histology embedding box |
| CN113432957A (en) * | 2021-06-28 | 2021-09-24 | 广州中医药大学第一附属医院 | Embedding box |
| WO2023082080A1 (en) * | 2021-11-10 | 2023-05-19 | Leica Biosystems Nussloch Gmbh | Cassette and embedding method using same |
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