CN206609217U - Lyophilized production line - Google Patents
Lyophilized production line Download PDFInfo
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- CN206609217U CN206609217U CN201621447816.XU CN201621447816U CN206609217U CN 206609217 U CN206609217 U CN 206609217U CN 201621447816 U CN201621447816 U CN 201621447816U CN 206609217 U CN206609217 U CN 206609217U
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- station
- lyophilized
- freeze
- bottle
- filling
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 46
- 230000006698 induction Effects 0.000 claims abstract description 28
- 238000011144 upstream manufacturing Methods 0.000 claims abstract description 11
- 239000000463 material Substances 0.000 claims description 20
- 230000004888 barrier function Effects 0.000 claims description 14
- 238000005406 washing Methods 0.000 claims description 8
- 230000009191 jumping Effects 0.000 claims description 6
- 238000005057 refrigeration Methods 0.000 claims description 3
- 238000003032 molecular docking Methods 0.000 claims description 2
- 230000008901 benefit Effects 0.000 abstract description 2
- 230000009467 reduction Effects 0.000 abstract description 2
- 239000003814 drug Substances 0.000 description 30
- 230000008014 freezing Effects 0.000 description 7
- 238000007710 freezing Methods 0.000 description 7
- 238000005096 rolling process Methods 0.000 description 7
- 229940079593 drug Drugs 0.000 description 4
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 235000015110 jellies Nutrition 0.000 description 2
- 239000008274 jelly Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
Landscapes
- Drying Of Solid Materials (AREA)
Abstract
The utility model discloses a kind of lyophilized production line, including reason bottle part, automatic feed/discharge induction system, filling station and lyophilized station, the automatic feed/discharge induction system is arranged between the reason bottle part and lyophilized station, the filling station is corresponding with the automatic feed/discharge induction system and is arranged on the lyophilized station upstream, N number of pre-freeze station is provided between the reason bottle part and filling station, wherein, N >=1, the pre-freeze station is provided with filling components and pre-freeze machine, the pre-freeze machine is arranged on the side of the automatic feed/discharge induction system, the transfer passage of the filling components correspondence automatic feed/discharge induction system is arranged on the upstream of the pre-freeze machine.Lyophilized production line of the present utility model has the advantages that to realize that lyophilized layering, reduction production cost, production efficiency are high.
Description
Technical field
The utility model is related to pharmaceutical production equipment, more particularly to a kind of lyophilized production line.
Background technology
Lyophilized production refers to medicine being frozen into solid-state at a lower temperature, then direct without liquid under vacuum conditions
Gaseous state is sublimed into, finally medicine is dehydrated.Existing lyophilized production line includes filling and stopper-adding machine, Cover-rolling machine and freeze dryer,
Medicine is freeze-dried after partly being jumped a queue through filling and stopper-adding machine is filling into freeze dryer, and the medicine after freezing is delivered to Cover-rolling machine and rolled
Lid completes production, and the production line can only be used for producing the freeze dried powder of unitary agent, but in actual production process, exist containing two
The medicine of kind or a variety of heterogeneities, filling several times and laminated freezing, existing lyophilized life are needed when producing this similar drug
Producing line is obviously difficult to the production requirement for meeting this similar drug.
Utility model content
The technical problems to be solved in the utility model is to overcome the deficiencies in the prior art to realize that layering is frozen there is provided one kind
The high lyophilized production line of dry, reduction production cost, production efficiency.
In order to solve the above technical problems, the utility model uses following technical scheme:
A kind of lyophilized production line, including reason bottle part, automatic feed/discharge induction system, filling station and lyophilized station, it is described
Automatic feed/discharge induction system is arranged between the reason bottle part and lyophilized station, the filling station and the automatic feed/discharge
Induction system is corresponding and is arranged on the lyophilized station upstream, and N number of pre-freeze station is provided between the reason bottle part and filling station,
Wherein, N >=1, the pre-freeze station is provided with filling components and pre-freeze machine, and it is defeated that the pre-freeze machine is arranged on the automatic feed/discharge
The side of system is sent, the transfer passage of the filling components correspondence automatic feed/discharge induction system is arranged on the pre-freeze machine
Upstream.
It is used as the further improvement of above-mentioned technical proposal:
The filling station is provided with filling components and jumps a queue component, and the filling components and component of jumping a queue are along the conveying
The conveying direction of passage is set gradually.
The automatic feed/discharge induction system includes foraminous conveyer and N+1 input and output material component, the foraminous conveyer docking
Between the reason bottle part and lyophilized station, the N+1 input and output material components correspond to N number of pre-freeze station and the jelly respectively
Dry station sets that automatic feed/discharge of the bottle in the pre-freeze machine or lyophilized station freeze dryer will be completed.
The input and output material component includes input and output material push rod, and the input and output material push rod is arranged on the foraminous conveyer away from described
The side of pre-freeze machine.
The pre-freeze machine has common refrigeration system with the freeze dryer on the lyophilized station.
The reason bottle part upstream is provided with bottle washing machine and dryer, the bottle washing machine and dryer along bottle conveying direction successively
Set.
The lyophilized station downstream is provided with Cover-rolling machine.
Provided with barrier is oriented between the pre-freeze machine and filling station, the guiding barrier is located at the foraminous conveyer, institute
State be oriented to barrier include can accommodate the multiple row bottle that the pre-freeze machine is exported bottle inlet section, it is described be oriented to barrier bottle outlet section by
Gradual change is narrow and is docked with the active conveying bottle screw rod on the filling station.
Compared with prior art, the utility model has the advantage of:
Lyophilized production line of the present utility model, is set in pre-freeze station, production process between resonable bottle part and filling station,
Enter pre-freeze station after medicine bottle manager's bottle part reason bottle, pre-freeze station is provided with filling components and pre-freeze machine, and medicine bottle is in pre-freeze station
On carried out by filling components filling, then delivered to by automatic feed/discharge induction system and pre-freeze carried out in pre-freeze machine, medicine bottle is in pre-freeze
After station pre-freeze to the pre-freezing temperature set, then by automatic feed/discharge induction system medicine bottle is exported, repeats above-mentioned pre-freeze step,
Until completing after last time pre-freeze, medicine bottle enters filling station, completes filling for the last time, and operation of partly being jumped a queue, with
Medicine bottle is delivered in the freeze dryer of lyophilized station by automatic feed/discharge induction system afterwards completes final lyophilized, according to actual production need
The quantity that pre-freeze station is set is sought, lyophilized production line of the present utility model can be realized need to filling several times and laminated freezing medicine
The production of product, expands the scope of application of lyophilized production line, reduces the production cost of pharmaceutical producing enterprise, pre-freeze is in pre-freeze
Station is completed, and is freezed station and freeze for the last time, medicine bottle is withouted waiting in process of production, improves production efficiency.
Brief description of the drawings
Fig. 1 is the structural representation of the first embodiment of the utility model.
Fig. 2 is the enlarged drawing at A in Fig. 1.
Fig. 3 is the structural representation of second of embodiment of the utility model.
Each label is represented in figure:
1st, bottle part is managed;21st, foraminous conveyer;22nd, input and output material component;3rd, filling station;31st, active conveying bottle screw rod;4th, station is freezed;
5th, filling components;6th, pre-freeze machine;7th, bottle washing machine;8th, dryer;9th, Cover-rolling machine;10th, jump a queue component;11st, it is oriented to barrier.
Embodiment
The utility model is described in further details below with reference to Figure of description and specific embodiment.
Figures 1 and 2 show that the utility model freezes the first embodiment of production line, the lyophilized production line includes reason bottle
Part 1, automatic feed/discharge induction system, filling station 3 and lyophilized station 4, automatic feed/discharge induction system set the resonable He of bottle part 1
Between lyophilized station 4, filling station 3 is corresponding with automatic feed/discharge induction system and is arranged on the lyophilized upstream of station 4, reason bottle part 1
N number of pre-freeze station is provided between filling station 3, wherein, N >=1, pre-freeze station is provided with filling components 5 and pre-freeze machine 6, in advance
Jelly machine 6 is arranged on the side of automatic feed/discharge induction system, the transfer passage of the corresponding automatic feed/discharge induction system of filling components 5
The upstream of pre-freeze machine 6 is arranged on, is set between resonable bottle part 1 and filling station 3 in pre-freeze station, production process, medicine bottle manager
Enter pre-freeze station after the bottle reason bottle of part 1, pre-freeze station is provided with filling components 5 and pre-freeze machine 6, and medicine bottle is on pre-freeze station by filling
Arrangement 5 carries out filling, is then delivered to by automatic feed/discharge induction system and pre-freeze is carried out in pre-freeze machine 6, medicine bottle is in pre-freeze station
After pre-freeze to the pre-freezing temperature set, then by automatic feed/discharge induction system medicine bottle is exported, repeat above-mentioned pre-freeze step, until
Complete after last time pre-freeze, medicine bottle enters filling station 3, complete filling for the last time, and operation of partly being jumped a queue, subsequent medicine
Bottle is delivered in the freeze dryer of lyophilized station 4 by automatic feed/discharge induction system completes final lyophilized, according to actual production demand
The quantity of pre-freeze station is set, it is necessary to pre-freeze several times, then several pre-freeze stations are set, lyophilized production line of the present utility model can be with
Realizing needs the production of filling several times and laminated freezing medicine, expands the scope of application of lyophilized production line, reduces medicine
The production cost of manufacturing enterprise, pre-freeze completes in pre-freeze station, freezes station and freeze for the last time, medicine bottle was being produced
Withouted waiting in journey, improve production efficiency.
In the present embodiment, filling station 3 is provided with filling components 5 and component 10 of jumping a queue, filling components 5 and component 10 of jumping a queue
Set gradually along the conveying direction of transfer passage 21, medicine bottle completes filling for the last time on filling station 3, and is partly jumped a queue
Operation, the lyophilized station 4 after the completion of partly jumping a queue into downstream completes last freeze.
In the present embodiment, automatic feed/discharge induction system includes foraminous conveyer 21 and N+1 input and output material component 22, transmission net
Band 21 is butted up against between reason bottle part 1 and lyophilized station 4, and N+1 input and output material component 22 corresponds to N number of pre-freeze station and lyophilized work respectively
Position 4 is set will complete automatic feed/discharge of the bottle in pre-freeze machine 6 or the freeze dryer of lyophilized station 4, and foraminous conveyer 21 is used for real
The conveying of existing medicine bottle, input and output material component 22 is used to realize input and output material of the medicine bottle in pre-freeze machine 6, freeze dryer.
In the present embodiment, input and output material component 22 includes input and output material push rod, and it is remote that input and output material push rod is arranged on foraminous conveyer 21
The side of pre-freeze machine 6, realizes medicine bottle in the input and output material in pre-freeze machine 6, freeze dryer using input and output material push rod.
In the present embodiment, pre-freeze machine 6 has common refrigeration system with the freeze dryer on lyophilized station 4, to simplify structure,
It is cost-effective.
In the present embodiment, the upstream of reason bottle part 1 is provided with bottle washing machine 7 and dryer 8, and bottle washing machine 7 and dryer 8 are conveyed along bottle
Direction is set gradually, and bottle washing machine 7 and dryer 8 can realize the cleaning and drying to medicine bottle respectively.
In the present embodiment, provided with barrier 11 is oriented between pre-freeze machine 6 and filling station 3, it is oriented to barrier 11 and is located at transmission net
Band 21, be oriented to barrier 11 include can accommodate the multiple row bottle that pre-freeze machine 6 is exported bottle inlet section, be oriented to barrier 11 bottle outlet section by
Gradual change is narrow and is docked with the active conveying bottle screw rod 31 on filling station 3, and active conveying bottle screw rod 31 can convey single-row bottle, sets and is oriented to barrier
11 make multiple row bottle progress into active conveying bottle screw rod 31, it is to avoid squeezing bottle occur and fall a bottle phenomenon.
Fig. 3 shows that the utility model freezes second of embodiment of production line, the embodiment and the first embodiment base
This is identical, differs only in:In the present embodiment, a pre-freeze station is set, that is, carries out a pre-freeze, and the lyophilized downstream of station 4
Provided with Cover-rolling machine 9, complete after freezing, the Cover-rolling machine 9 that medicine bottle is delivered into downstream carries out rolling lid.
Although the utility model is disclosed above with preferred embodiment, but it is not limited to the utility model.It is any
Those skilled in the art, in the case where not departing from technical solutions of the utility model scope, all using the disclosure above
Technology contents technical solutions of the utility model are made with many possible variations and modification, or be revised as the equivalent of equivalent variations
Embodiment.Therefore, every content without departing from technical solutions of the utility model, according to the utility model technical spirit to real above
Any simple modifications, equivalents, and modifications that example is done are applied, all should be fallen in the range of technical solutions of the utility model protection.
Claims (8)
1. a kind of lyophilized production line, including reason bottle part(1), automatic feed/discharge induction system, filling station(3)With lyophilized station
(4), the automatic feed/discharge induction system be arranged on it is described reason bottle part(1)With lyophilized station(4)Between, the filling station
(3)It is corresponding with the automatic feed/discharge induction system and be arranged on the lyophilized station(4)Upstream, it is characterised in that:The reason
Bottle part(1)With filling station(3)Between be provided with N number of pre-freeze station, wherein, N >=1, the pre-freeze station be provided with filling components
(5)With pre-freeze machine(6), the pre-freeze machine(6)It is arranged on the side of the automatic feed/discharge induction system, the filling components
(5)The transfer passage of the correspondence automatic feed/discharge induction system is arranged on the pre-freeze machine(6)Upstream.
2. lyophilized production line according to claim 1, it is characterised in that:The filling station(3)It is provided with filling components
(5)With component of jumping a queue(10), the filling components(5)With component of jumping a queue(10)Set successively along the conveying direction of the transfer passage
Put.
3. lyophilized production line according to claim 1 or 2, it is characterised in that:The automatic feed/discharge induction system includes
Foraminous conveyer(21)With N+1 input and output material component(22), the foraminous conveyer(21)Butt up against the reason bottle part(1)With lyophilized work
Position(4)Between, the N+1 input and output material components(22)N number of pre-freeze station and the lyophilized station are corresponded to respectively(4)Set
So that bottle will be completed in the pre-freeze machine(6)Or lyophilized station(4)Automatic feed/discharge in freeze dryer.
4. lyophilized production line according to claim 3, it is characterised in that:The input and output material component(22)Pushed away including input and output material
Bar, the input and output material push rod is arranged on the foraminous conveyer(21)Away from the pre-freeze machine(6)Side.
5. lyophilized production line according to claim 1 or 2, it is characterised in that:The pre-freeze machine(6)With the lyophilized station
(4)On freeze dryer there is common refrigeration system.
6. lyophilized production line according to claim 1 or 2, it is characterised in that:The reason bottle part(1)Upstream is provided with bottle washing machine
(7)And dryer(8), the bottle washing machine(7)And dryer(8)Set gradually along bottle conveying direction.
7. lyophilized production line according to claim 1 or 2, it is characterised in that:The lyophilized station(4)Downstream, which is provided with, rolls lid
Machine(9).
8. lyophilized production line according to claim 3, it is characterised in that:The pre-freeze machine(6)With filling station(3)Between
Provided with guiding barrier(11), the guiding barrier(11)Positioned at the foraminous conveyer(21)Top, the guiding barrier(11)Bag
The pre-freeze machine can be accommodated by including(6)The bottle inlet section of the multiple row bottle exported, the guiding barrier(11)Bottle outlet section gradually become
It is narrow and with the filling station(3)On active conveying bottle screw rod(31)Docking.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201621447816.XU CN206609217U (en) | 2016-12-27 | 2016-12-27 | Lyophilized production line |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201621447816.XU CN206609217U (en) | 2016-12-27 | 2016-12-27 | Lyophilized production line |
Publications (1)
Publication Number | Publication Date |
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CN206609217U true CN206609217U (en) | 2017-11-03 |
Family
ID=60171567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201621447816.XU Active CN206609217U (en) | 2016-12-27 | 2016-12-27 | Lyophilized production line |
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CN (1) | CN206609217U (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108020027A (en) * | 2017-12-29 | 2018-05-11 | 楚天科技股份有限公司 | A kind of bulk pharmaceutical chemicals freeze production line and its technological process |
CN108931104A (en) * | 2018-07-31 | 2018-12-04 | 湖南美可达生物资源股份有限公司 | A kind of continuous pre-freeze machine of macleaya cordata |
CN112896657A (en) * | 2021-02-05 | 2021-06-04 | 重庆华森制药股份有限公司 | Intelligent production line and production method of freeze-dried powder |
-
2016
- 2016-12-27 CN CN201621447816.XU patent/CN206609217U/en active Active
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108020027A (en) * | 2017-12-29 | 2018-05-11 | 楚天科技股份有限公司 | A kind of bulk pharmaceutical chemicals freeze production line and its technological process |
CN108931104A (en) * | 2018-07-31 | 2018-12-04 | 湖南美可达生物资源股份有限公司 | A kind of continuous pre-freeze machine of macleaya cordata |
CN112896657A (en) * | 2021-02-05 | 2021-06-04 | 重庆华森制药股份有限公司 | Intelligent production line and production method of freeze-dried powder |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: TRUKING TECHNOLOGY Ltd. Assignor: TRUKING INTELLIGENT ROBOT (CHANGSHA) Co.,Ltd. Contract record no.: X2023980047829 Denomination of utility model: Freeze drying production line Granted publication date: 20171103 License type: Common License Record date: 20231122 |
|
EE01 | Entry into force of recordation of patent licensing contract |