CN206566773U - A kind of intelligent membrane module of resolving chiral material - Google Patents
A kind of intelligent membrane module of resolving chiral material Download PDFInfo
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- CN206566773U CN206566773U CN201621336744.1U CN201621336744U CN206566773U CN 206566773 U CN206566773 U CN 206566773U CN 201621336744 U CN201621336744 U CN 201621336744U CN 206566773 U CN206566773 U CN 206566773U
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- membrane module
- hollow fiber
- putamina
- film
- chiral
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Abstract
The utility model discloses a kind of intelligent membrane module of resolving chiral material, including hollow fiber film yarn, putamina and epoxy resin end seal, the material of the hollow fiber ultrafiltration film silk is polyvinylidene fluoride modified material, and the material of the putamina is igelite.Intelligent membrane module prepared by the utility model has used chiral monomer L phenylalanine ethyl ester acrylamides, because the presence of asymmetric carbon atom in chiral monomer, by 3 recognition principles, different active forces are produced to optically active substance, so as to reach the effect of fractionation.It is difficult to which overcome selectivity and flux in classical resolution film while the shortcoming improved.
Description
Technical field
The utility model is related to intelligent macromolecule material field, and in particular to one kind can with resolution of racemic material, and
Have the novel chiral separating film module of temperature sensitivity concurrently.
Background technology
In recent years, the usage amount of optical homochiral medicine is increased year by year on world market.Domestic and international market is to medicine
Optical purity requires more and more higher.FDA (Food and Drug Adminstration) in 1992 proposes the development guiding principle on optics drugs
Will, it is indicated that toxicological effect, drug action and the clinical effect of each enantiomer must be clearly indicated that when new drug is used in specification
Really, and if two kinds of enantiomers have obvious difference in drug action and toxicological effect, it is desirable to must be with optical voidness form
Listing.Supply falls short of demand for optics chiral drug, and this is by as the chief motivation for promoting chiral resolution technological direction constantly maturation.
Method for racemate resolution have much be broadly divided into it is following several：Crystallization fractionation, chemical resolution, biology are torn open
Point, the method such as Chromatographic resolution, UF membrane.Because membrane separation process has, cost is low, separative efficiency is high, it is pollution-free, be easy to amplification etc.
Advantage causes the concern of researchers.
Intelligent seperation film refers to when external environmental condition (temperature, pressure, pH, light, ionic strength, electric field etc.) changes
During change, the class seperation film that fenestra size, permeance property, mass-transfer performance, interface performance etc. can change therewith.This film was both
Characteristic with traditional separation membrane material, imparts the new feature of response external environment again.At present, the polymer used in industry
Seperation film typically can not all be responded in environmental change to external world, its application field be limited, in order to expand polymer separation film
Application, developing intellectual resource seperation film turn into research new focus.
In order to reach the purpose of intelligence fractionation, this research has hand concurrently using phenylalanine as object, research and development one kind is split
Property identification and temperature sensitivity novel chiral separating film module.
Utility model content
For the shortcoming and defect of existing method for splitting, the technical problem that the utility model is intended to solve, which is to provide one kind, to be had
The novel chiral separating film module of high flux and high selectivity.
The technical scheme in the invention for solving the technical problem is：
A kind of intelligent membrane module of resolving chiral material, by hollow fiber film yarn, putamina and epoxy resin end seal structure
Into the hollow fiber ultrafiltration film silk and epoxy resin end seal are respectively arranged at two ends in formwork.
As the improvement of above-mentioned technical proposal, the material of the hollow fiber ultrafiltration film silk is polyvinylidene fluoride modified material, institute
The material for stating putamina is igelite.
The preparation process of the polyvinylidene fluoride modified material：
(1) using L-phenylalanine carbethoxy hydrochloride as raw material, occur acylation reaction with acryloyl chloride, chiral monomer is made
(AAc-L-PheEt).Using chiral monomer and NIPA as the temperature sensitive chiral copolymerization microgel P of Material synthesis
(NIPAAm-co-AAc-L-Phe)。
(2) alkali process is carried out to PVDF, it is temperature sensitive that the PVDF after processing and NIPAAm copolymerization is generated into PVDF-g-PNIPAAm
Matrix.Microgel and PVDF-g-PNIPAAm are blended, using PEG as pore-foaming agent, DMF is solvent, using forming film with phase transformation method work
It is the polyvinylidene fluoride modified material needed for membrane module that chiral separation hollow-fibre membrane, which is made, in skill.
The polyvinyl chloride putamina is managed for commercialization DN150PVC.
The beneficial effect that the utility model is brought has：
Intelligent membrane module raw material prepared by the utility model is Kynoar, because it is that a kind of have excellent heat
The fluoroplastics of stability corrosion resistance, are soluble in the good solvents such as dimethyl acetamide, dimethylformamide, can be used submergence heavy
It is heat-resisting that shallow lake method is prepared into a class, ultraviolet light resistant, acid and alkali-resistance, the high-performance seperation film of organic solvent-resistant.
Intelligent membrane module prepared by the utility model has used chiral monomer L-phenylalanine ethyl ester acrylamide, because
The presence of asymmetric carbon atom in chiral monomer, by 3 recognition principles, different active forces are produced to optically active substance, so that
Reach the effect of fractionation.It is difficult to which overcome selectivity and flux in classical resolution film while the shortcoming improved.
Preparation method prepares hollow-fibre membrane using phase inversion, and hollow-fibre membrane not only has high loading density, pole
High specific surface area, and it is simple in construction, the possibility of germ contamination can be effectively reduced, simplifies cleaning operation.Leak detection is repaiied in addition
It is convenient to mend, and rejection is stable, and service life is long, and this is that film splits the industrialized trend of industry.
Brief description of the drawings
Fig. 1 is smart membrane material schematic diagram；
Reference name in figure corresponding to each sequence number is as follows：
1- hollow fiber ultrafiltrations film silk；2- putaminas；3- waste liquid outlets；4- products exports；5- epoxy resin end seals；6- stostes enter
Mouthful.
Embodiment
The following examples can make those skilled in the art that the utility model is more fully understood, but not in any way
Limit the utility model.
Referring to Fig. 1, the utility model includes hollow fiber ultrafiltration film silk 1, putamina 2 and epoxy resin end seal 5.Stoste is racemic
Solution, from the injection of the end of stoste entrance 6, into hollow fiber ultrafiltration film silk 1, by selectively acting, a kind of chiral monomer is through hollow
Ultrafiltration membrane filaments 1, penetrant is the product needed for being come out from products export 4, and waste liquid flows out from waste liquid outlet 3.
Claims (2)
1. a kind of intelligent membrane module of resolving chiral material, it is characterised in that：Including hollow fiber ultrafiltration film silk, putamina and epoxy resin
End seal, the hollow fiber ultrafiltration film silk and epoxy resin end seal are respectively arranged at two ends in formwork.
2. the intelligent membrane module of the resolving chiral material according to claim 1, it is characterised in that：The hollow fiber ultrafiltration film
The material of silk is polyvinylidene fluoride modified material, and the material of the putamina is igelite.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621336744.1U CN206566773U (en) | 2016-12-07 | 2016-12-07 | A kind of intelligent membrane module of resolving chiral material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621336744.1U CN206566773U (en) | 2016-12-07 | 2016-12-07 | A kind of intelligent membrane module of resolving chiral material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206566773U true CN206566773U (en) | 2017-10-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621336744.1U Active CN206566773U (en) | 2016-12-07 | 2016-12-07 | A kind of intelligent membrane module of resolving chiral material |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206566773U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110975642A (en) * | 2019-12-31 | 2020-04-10 | 江苏美能膜材料科技有限公司 | High-strength hollow fiber membrane for filtering beverage and wine, membrane component and preparation process of membrane |
-
2016
- 2016-12-07 CN CN201621336744.1U patent/CN206566773U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110975642A (en) * | 2019-12-31 | 2020-04-10 | 江苏美能膜材料科技有限公司 | High-strength hollow fiber membrane for filtering beverage and wine, membrane component and preparation process of membrane |
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