CN205844190U - A kind of paper substrate micro fluidic device - Google Patents

A kind of paper substrate micro fluidic device Download PDF

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Publication number
CN205844190U
CN205844190U CN201620748955.XU CN201620748955U CN205844190U CN 205844190 U CN205844190 U CN 205844190U CN 201620748955 U CN201620748955 U CN 201620748955U CN 205844190 U CN205844190 U CN 205844190U
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CN
China
Prior art keywords
fluidic device
micro fluidic
paper substrate
substrate micro
paper
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Expired - Fee Related
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CN201620748955.XU
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Chinese (zh)
Inventor
丁玉庭
张芬君
赵文革
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Zhejiang Long Biotech Co Ltd
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Zhejiang Long Biotech Co Ltd
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Priority to CN201620748955.XU priority Critical patent/CN205844190U/en
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Abstract

The utility model discloses a kind of paper substrate micro fluidic device, sampling number of times during reducing the detection of paper substrate micro fluidic device, it is characterized in that: the edge of described hydrophilic area is provided with a hydrophobic border, the center of described hydrophilic area is provided with sample-adding circular hole, the outer rim of described sample-adding circular hole is communicated with the capillary channel of some circumference array, and the outer end of some described capillary channels is all communicated with detection hole.Each capillary channel of the present utility model has the length and width communicated, and the size in each detection hole is the most identical, therefore time by reagent paper horizontal positioned, sample liquid hold-up theory in each detection hole is identical, different fluorescent probes is added in difference detection hole, reach to detect Multiple components or the purpose of ion, it is achieved variation detection.

Description

A kind of paper substrate micro fluidic device
Technical field
This utility model relates to microfluidic analysis device, is specifically related to a kind of paper substrate micro fluidic device.
Background technology
Paper substrate micro fluidic device is the microfluidic analysis device with paper as substrate, its objective is by experiment detection in multiple Experimental procedure focuses on a small paper chip.Due to paper substrate micro fluidic device due to filter paper low cost, capillarity substantially, And filter paper is easily handled, so paper substrate micro fluidic device is compared with other microfluidic analysis devices, there is obvious advantage, extensively General application and the every field such as medical diagnosis, test in laboratory.
Paper substrate micro fluidic device utilizes hydrophobic layer to form detection zone, and in general, for avoiding interference, same detection zone only can Being used for a certain composition or ion, when having multiple composition to be measured or ion in sample, paper substrate micro fluidic device is accomplished by setting Put multiple independent detection zone, this just require repeatedly to sample and every sub-sampling metering uniformly, operation is complicated, difficulty is big.
Utility model content
In order to reduce the sampling number of times during paper substrate micro fluidic device detects, this utility model provides one and has many The paper substrate micro fluidic device of individual detection zone.
The technical solution adopted in the utility model is as follows:
A kind of paper substrate micro fluidic device, including reagent paper, described reagent paper is provided with hydrophilic area, and the edge of described hydrophilic area is provided with A number hydrophobic border, the center of described hydrophilic area is provided with sample-adding circular hole, and the outer rim of described sample-adding circular hole is communicated with some Circle-Arrays The capillary channel of row, the outer end of some described capillary channels is all communicated with detection hole.
A diameter of 6mm of described sample-adding circular hole, some described capillary channels are wide isometric, and the width of shown capillary channel is 2mm。
A described hydrophobic border is wax floor.
The width on a described hydrophobic border is 3mm.
The lower section of described reagent paper is provided with hydrophobic layer.
Described hydrophobic layer is adhesive tape.
Described reagent paper is provided with some hydrophilic contrast districts, and described contrast district outer rim is provided with No. two hydrophobic borders.
The beneficial effects of the utility model are:
Each capillary channel of the present utility model has a length and width communicated, and the size also phase in each detection hole With, time therefore by reagent paper horizontal positioned, the sample liquid hold-up theory in each detection hole is identical, adds difference in difference detection hole Fluorescent probe, reach to detect Multiple components or the purpose of ion, it is achieved variation detection.
Accompanying drawing explanation
Fig. 1 is the outline drawing of this utility model embodiment.
Fig. 2 is the explosive view of this utility model embodiment.
Hydrophobic border 2, hydrophilic area 1, hydrophobic layer 3, hydrophobic border 5, contrast district 4, two, sample-adding circular hole 11, capillary are led to Road 12, detection hole 13.
Detailed description of the invention
The utility model is described in further detail with embodiment below in conjunction with the accompanying drawings.
In embodiment, as it is shown in figure 1, a kind of paper substrate micro fluidic device, including reagent paper, described reagent paper is provided with hydrophilic area 1, The edge of described hydrophilic area 1 is provided with the center of hydrophilic area 1 described in a hydrophobic border 2 and is provided with sample-adding circular hole 11, described sample-adding circle The outer rim in hole 11 is communicated with the capillary channel 12 of some circumference array, and the outer end of some described capillary channels 12 is all communicated with detection Hole 13.Each capillary channel 12 of the present embodiment has a length and width communicated, and the size also phase in each detection hole 13 With, time therefore by reagent paper horizontal positioned, the sample liquid hold-up theory in each detection hole 13 is identical, adds in difference detection hole 13 Different fluorescent probes, just can reach to detect Multiple components or the purpose of ion, it is achieved variation detection.
In embodiment, as it is shown in figure 1, a diameter of 6mm of described sample-adding circular hole, some described capillary channels are wide isometric, The width of shown capillary channel is 2mm.In the present embodiment, all of capillary channel 12 is wide isometric, it is ensured that in detection hole 13 Sample liquid hold-up is identical.
In embodiment, as shown in Figure 1 and Figure 2, a described hydrophobic border 2 is wax floor, the width on a described hydrophobic border 2 Degree is 3mm.The present embodiment selects wax layer as hydrophobic layer, has easy to process, the convenient passage of Waste Paper Handling.
In embodiment, as in figure 2 it is shown, the lower section of described reagent paper is provided with hydrophobic layer 3, described hydrophobic layer 3 is adhesive tape.This enforcement The hydrophobic layer 3 of example prevents the paper of the saturating reagent paper of sample immersion from carrying on the back.
In embodiment, as it is shown in figure 1, described reagent paper is provided with some hydrophilic contrast districts 4, described contrast district 4 outer rim sets There are No. two hydrophobic borders 5.The contrast district 4 of the present embodiment is used for accommodating sample liquid, whether can send fluorescence by direct visual comparison fluorescent probe.
Obviously, above-described embodiment of the present utility model is merely to illustrate that this utility model example, and not Restriction to embodiment of the present utility model.For those of ordinary skill in the field, on the basis of described above On can also make change or the variation of other multi-forms.Here without also all of embodiment being given poor example. And these belong to obvious change that connotation of the present utility model amplified out or variation still falls within this utility model Protection domain.

Claims (7)

1. a paper substrate micro fluidic device, including reagent paper, described reagent paper is provided with hydrophilic area (1), the edge of described hydrophilic area (1) It is provided with a hydrophobic border (2), it is characterised in that: the center of described hydrophilic area (1) is provided with sample-adding circular hole (11), described sample-adding circle The outer rim in hole (11) is communicated with the capillary channel (12) of some circumference array, and the outer end of some described capillary channels (12) all connects There is detection hole (13).
Paper substrate micro fluidic device the most according to claim 1, it is characterised in that: described sample-adding circular hole (11) a diameter of 6mm, some described capillary channels (12) are wide isometric, and the width of shown capillary channel (12) is 2mm.
Paper substrate micro fluidic device the most according to claim 1, it is characterised in that: a described hydrophobic border (2) is wax floor.
4. according to the paper substrate micro fluidic device described in claim 1 or 3, it is characterised in that: the width of a described hydrophobic border (2) Degree is 3mm.
Paper substrate micro fluidic device the most according to claim 1, it is characterised in that: the lower section of described reagent paper is provided with hydrophobic layer (3).
Paper substrate micro fluidic device the most according to claim 5, it is characterised in that: described hydrophobic layer (3) is adhesive tape.
Paper substrate micro fluidic device the most according to claim 1, it is characterised in that: described reagent paper is provided with some hydrophilic right Ratio district (4), described contrast district (4) outer rim is provided with No. two hydrophobic borders (5).
CN201620748955.XU 2016-07-18 2016-07-18 A kind of paper substrate micro fluidic device Expired - Fee Related CN205844190U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201620748955.XU CN205844190U (en) 2016-07-18 2016-07-18 A kind of paper substrate micro fluidic device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201620748955.XU CN205844190U (en) 2016-07-18 2016-07-18 A kind of paper substrate micro fluidic device

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CN205844190U true CN205844190U (en) 2016-12-28

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108288578A (en) * 2017-12-31 2018-07-17 宁波大学 Paper substrate sampling device and method
CN111044499A (en) * 2019-07-22 2020-04-21 集美大学 Carbon quantum dot fluorescence test paper sheet for simultaneously detecting four heavy metals in water and application thereof
CN111474155A (en) * 2020-04-28 2020-07-31 广东博创佳禾科技有限公司 Ralstonia solanacearum solution guiding device
CN111715312A (en) * 2019-03-21 2020-09-29 首都师范大学 Paper-based micro-fluidic chip for multi-parameter analysis of water quality detection and manufacturing method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108288578A (en) * 2017-12-31 2018-07-17 宁波大学 Paper substrate sampling device and method
WO2019129269A1 (en) * 2017-12-31 2019-07-04 宁波大学 Paper-based sample feeding device and method
CN108288578B (en) * 2017-12-31 2020-08-11 宁波大学 Paper-based sample injection device and method
CN111715312A (en) * 2019-03-21 2020-09-29 首都师范大学 Paper-based micro-fluidic chip for multi-parameter analysis of water quality detection and manufacturing method thereof
CN111044499A (en) * 2019-07-22 2020-04-21 集美大学 Carbon quantum dot fluorescence test paper sheet for simultaneously detecting four heavy metals in water and application thereof
CN111474155A (en) * 2020-04-28 2020-07-31 广东博创佳禾科技有限公司 Ralstonia solanacearum solution guiding device

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20161228

Termination date: 20210718