CN205586001U - Be used for electrometric implanted brain electrode of muroid brain primary vision cortex brain - Google Patents
Be used for electrometric implanted brain electrode of muroid brain primary vision cortex brain Download PDFInfo
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- CN205586001U CN205586001U CN201620313921.8U CN201620313921U CN205586001U CN 205586001 U CN205586001 U CN 205586001U CN 201620313921 U CN201620313921 U CN 201620313921U CN 205586001 U CN205586001 U CN 205586001U
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Abstract
The utility model provides a be used for electrometric implanted brain electrode of muroid brain primary vision cortex brain, it includes electrode cap, two wire electrode arrays, flexible circuit board and connectors, every wire electrode array includes many wire electrodes, and every wire electrode extends and installs in the lower surface of electrode cap along vertical direction, at least partial wire electrode in wire electrode array configures into the cerebral single mesh of muroid district carrying out the brain electrical measurement, and at least partial wire electrode in another wire electrode array configures into muroid cerebral pair of mesh district carrying out the brain electrical measurement, the one end of flexible circuit board is connected with the top route electricity of electrode cap, the connector is installed in the other end of flexible circuit board, configures the signal that the collection of output implanted brain electrode obtained into. This implanted brain electrode can obtain reliable stable EEG signal abundant and fast, overcomes EEG signal and gathers insufficient obstacle, still can place the wire electrode in the abundant position of EEG signal, the EEG signal of collection is more accurate.
Description
Technical field
This utility model relates to the EEG measuring of muroid brain primary visual cortex, particularly relates to a kind of implanted brain electrode for muroid brain primary visual cortex EEG measuring.
Background technology
In recent years, brain science based on brain-computer interface development is more and more, and brain-computer interface technology is that the direct of foundation between human brain with computer or other electronic equipments exchanges and control passage.Brain-computer interface technology is widely used to multiple fields such as neuroscience, psychological cognition science, biomedical engineering, clinical medicine, it is possible to the implanted brain electrode research that recorded neuron level electrical signal is developed rapidly.
The common linear brain electrode of implanted brain electrode, on linear brain electrode, general meeting integrated electronic circuit, flexibly ribbon conductor and microfluidic channel, can form arbitrary two dimensional surface shape in the region selected.But, for the most fully gathering white mice brain primary visual cortex EEG signals, existing linear brain electrode cannot meet requirement.Therefore, the most fully gathering white mice brain primary visual cortex EEG signals for brain electrode is an extremely urgent problem.
Utility model content
The purpose of this utility model is intended to overcome the problems referred to above or solve the problems referred to above at least in part, it is difficult to fully collect the defect of muroid specific region EEG signals for existing brain electrode technology, there is provided a kind of implanted brain electrode, fully to gather muroid brain primary visual cortex EEG signals.
Specifically, this utility model provides a kind of implanted brain electrode for muroid brain primary visual cortex EEG measuring, and it includes electrode cap, two wire electrode arrays, flexible PCB and adapter；
Each described wire electrode array includes many wire electrodes, and every described wire electrode vertically extends and be installed on the lower surface of described electrode cap, and electrically connects with the bottom passageway of described electrode cap；At least part of described wire electrode in one described wire electrode array is configured to the monocular district of described muroid brain is carried out EEG measuring, and at least part of described wire electrode in another described wire electrode array is configured to the binocular district of described muroid brain is carried out EEG measuring；
One end of described flexible PCB electrically connects with the bottom passageway of described electrode cap；
Described adapter is installed on the other end of described flexible PCB, is configured to export the signal that described implanted brain electrode collects.
Further, in many described wire electrodes of each described wire electrode array, distance between the lower surface of the most advanced and sophisticated and described electrode cap of the described wire electrode that the lower surface of electrode cap described in distance between two tips is nearest is the first distance；
In many described wire electrodes of each described wire electrode array, the distance between the lower surface of the most advanced and sophisticated and described electrode cap of the described wire electrode that the lower surface of electrode cap described in distance between two tips is farthest is second distance；
Difference between described second distance and described first distance is less than or equal to 3mm.
Further, the tip of many described wire electrodes of each described wire electrode array is in the same plane.
Further, every described wire electrode includes tinsel and the insulating barrier being arranged on described part perisporium wiry.
Further, described tinsel is made up of platinumiridio or nichrome；
Described insulating barrier is made up of Formvar biocompatibility insulant.
Further, the monocular district to described muroid brain carries out the described wire electrode of EEG measuring and is arranged such that to be uniformly distributed in the monocular district of described muroid brain；
The described wire electrode that the binocular district of described muroid brain carries out EEG measuring is arranged such that to be uniformly distributed in the binocular district of described muroid brain.
Further, described implanted brain electrode also includes that electrode box, described electrode cap are installed in described electrode box, and described electrode box is stretched out at the tip of every described wire electrode.
Further, described electrode box includes:
Box body, it has base plate and the first side plate, and the lower surface of described electrode cap is installed on the upper surface of described base plate, and described one end of described flexible PCB is installed on described first side plate；
Lid, it has top board, two the second relative side plates, and the 3rd side plate being oppositely arranged with described first side plate, and described lid is removably installed in described box body.
Further, the quantity of the described wire electrode that the monocular district to described muroid brain carries out EEG measuring is 8；Quantity to the described wire electrode that the binocular district of described muroid brain carries out EEG measuring is 8.
Further, described implanted brain electrode also includes two ground wire electrode silks being used as ground wire, every described ground wire electrode silk vertically extends and is installed on the lower surface of described electrode cap, and electrically connects with the bottom passageway of described electrode cap, and has the structure identical with described wire electrode.
Implanted brain electrode of the present utility model is because having two wire electrode arrays, and the distribution shape of many wire electrodes agrees with mutually with muroid brain primary visual cortex in two wire electrode arrays, so reliable and stable EEG signals can fully and quickly be obtained, overcome the obstacle that eeg signal acquisition is insufficient, thus solve gathering the problem that muroid primary visual cortex eeg signal acquisition is insufficient all the time；Wire electrode also can be positioned over the position that EEG signals is abundant, and the EEG signals of collection is the most accurate.Additionally, implanted brain electrode structure of the present utility model is the most ingenious, performance is the most prominent.
Accompanying drawing explanation
Describe specific embodiments more of the present utility model the most by way of example, and not by way of limitation in detail.Reference identical in accompanying drawing denotes same or similar parts or part.It should be appreciated by those skilled in the art that what these accompanying drawings were not necessarily drawn to scale.In accompanying drawing:
Fig. 1 is the schematic diagram of the implanted brain electrode according to one embodiment of this utility model；
Fig. 2 is the schematic diagram at another visual angle of implanted brain electrode shown in Fig. 1；
Fig. 3 is the schematic quick-fried according to figure of implanted brain electrode shown in Fig. 1；
Fig. 4 is the schematic local structural graph of implanted brain electrode shown in Fig. 1.
Detailed description of the invention
According to below in conjunction with the accompanying drawing detailed description to this utility model specific embodiment, those skilled in the art will become more apparent from of the present utility model above-mentioned and other purposes, advantage and feature.
Fig. 1 is the schematic diagram of the implanted brain electrode according to one embodiment of this utility model.As it is shown in figure 1, and referring to figs. 2 to Fig. 4, this utility model embodiment provides a kind of implanted brain electrode for muroid brain primary visual cortex EEG measuring, and it includes 20, two wire electrode arrays 30 of electrode cap, flexible PCB 40 and adapter 50.
Each wire electrode array 30 includes many wire electrodes 31, and every wire electrode 31 vertically extends and be installed on the lower surface of electrode cap 20, and electrically connects with the bottom passageway of electrode cap 20.In two wire electrode arrays 30, the distribution shape of many wire electrodes 31 agrees with mutually with muroid brain primary visual cortex；It is to say, at least part of wire electrode 31 in a wire electrode array 30 is configured to the monocular district of muroid brain is carried out EEG measuring, at least part of wire electrode 31 in another wire electrode array 30 is configured to the binocular district of muroid brain is carried out EEG measuring.In this utility model embodiment, all wire electrodes 31 in each wire electrode array 30 are used to EEG measuring.
One end of flexible PCB 40 electrically connects with the bottom passageway of electrode cap 20.Adapter 50 is installed on the other end of flexible PCB 40, is configured to export the signal that implanted brain electrode collects.
In embodiments more of the present utility model, in many wire electrodes 31 of each wire electrode array 30, the distance between tip and the lower surface of electrode cap 20 of the wire electrode 31 that the lower surface of distance between two tips electrode cap 20 is nearest is the first distance.In many wire electrodes 31 of each wire electrode array 30, the distance between tip and the lower surface of electrode cap 20 of the wire electrode 31 that the lower surface of distance between two tips electrode cap 20 is farthest is second distance.Especially, the difference between second distance and the first distance is less than or equal to 3mm, to gather the signal of different depth.In some optional embodiments, the tip of many wire electrodes 31 of each wire electrode array 30 is in the same plane.The tip of all wire electrodes 31 can be on same plane.
In order to preferably measure, every wire electrode 31 includes tinsel and the insulating barrier being arranged on part perisporium wiry.Tinsel is made up of platinumiridio or nichrome, and insulating barrier is made up of Formvar biocompatibility insulant.Insulating barrier can use coating processes to be coated on tinsel, then tip wiry does sharpening process and exposes tinsel.The wire electrode 31 that the monocular district of muroid brain carries out EEG measuring is arranged such that to be uniformly distributed in the monocular district of muroid brain.The wire electrode 31 that the binocular district of muroid brain carries out EEG measuring is arranged such that to be uniformly distributed in the binocular district of muroid brain.
In embodiments more of the present utility model, implanted brain electrode also includes that electrode box 60, electrode cap 20 are installed in electrode box 60, and electrode box 60 is stretched out at the tip of every wire electrode 31.Specifically, electrode box 60 includes box body and is removably installed in the lid of box body.Box body has base plate 61 and the first side plate 62, and the lower surface of electrode cap 20 is installed on the upper surface of base plate 61, and one end of flexible PCB 40 is installed on the first side plate 62.Lid has the second side plate 64 that 63, two, top board is relative, and the 3rd side plate 65 being oppositely arranged with the first side plate 62.Lid can be connected in box body.
In embodiments more of the present utility model, the size of electrode cap 20 may be designed as 12.7cm × 12.7cm × 5cm.The size of box body may be designed as 14cm × 14cm × 14cm.The length of flexible PCB 40 may be designed to 28cm length.Quantity to the wire electrode 31 that the monocular district of muroid brain carries out EEG measuring is 8, and the quantity of the wire electrode 31 that the binocular district of muroid brain is carried out EEG measuring is 8.
In this embodiment, implanted brain electrode also includes two ground wire electrode silks being used as ground wire, every ground wire electrode silk vertically extends and is installed on the lower surface of electrode cap 20, and electrically connects with the bottom passageway of electrode cap 20, and has the structure identical with wire electrode 31.In some alternate embodiment, two ground wire electrode silks also can be integrated in two wire electrode arrays 30.
Flexible PCB 40 can have 18 paths, and adapter 50 is 18 channel connectors 50.One end of two-way in flexible PCB 40 can be connected with ground wire electrode silk 31, and the other end connects adapter 50, using as ground paths.One end of remaining 16 path of flexible PCB 40 electrically connects with 16 wire electrodes 31 respectively, and the other end connects adapter 50.In 16 wire electrodes 31,8 are evenly distributed on white mice brain monocular district, and other 8 are evenly distributed on white mice brain binocular district, and such distribution mode can more fully gather the EEG signals of white mice brain primary visual cortex.
White mice in use, can first be anaesthetized by the implanted brain electrode of this utility model embodiment, and removal head, by hair, is fixed on stereotaxic instrument, then carries out disinfection skin with iodine tincture and ethanol, cuts skin of head, exposes skull.Punch white mice brain with appropriately sized drill bit and form electrode hole, during operation, be careful not to injured brain tissue.Finally the implanted brain electrode of this utility model embodiment is clamped on stereotaxic instrument, adjust wire electrode 31 position, each wire electrode 31 is made to be directed at white mice primary vision region, when eletrode tip just contacts cerebral tissue, declining the clamping limb of stereotaxic instrument lentamente, the degree of depth making wire electrode 31 implant is 0.5mm to 0.8mm.In order to reduce in implantation process the damage organized, generally use air hammer and the implanted brain electrode of this utility model embodiment is squeezed into cerebral tissue.In other embodiments of the present utility model, it is possible to use rat etc. are tested.
So far, those skilled in the art will recognize that, multiple exemplary embodiment of the present utility model is illustrate and described although the most detailed, but, in the case of without departing from this utility model spirit and scope, still can directly determine according to this utility model disclosure or derive other variations or modifications of many meeting this utility model principle.Therefore, scope of the present utility model is it is understood that and regard as covering other variations or modifications all these.
Claims (10)
1. the implanted brain electrode for muroid brain primary visual cortex EEG measuring, it is characterised in that include electrode cap, two wire electrode arrays, flexible PCB and adapter；
Each described wire electrode array includes many wire electrodes, and every described wire electrode vertically extends and be installed on the lower surface of described electrode cap, and electrically connects with the bottom passageway of described electrode cap；At least part of described wire electrode in one described wire electrode array is configured to the monocular district of described muroid brain is carried out EEG measuring, and at least part of described wire electrode in another described wire electrode array is configured to the binocular district of described muroid brain is carried out EEG measuring；
One end of described flexible PCB electrically connects with the bottom passageway of described electrode cap；
Described adapter is installed on the other end of described flexible PCB, is configured to export the signal that described implanted brain electrode collects.
Implanted brain electrode the most according to claim 1, it is characterised in that
In many described wire electrodes of each described wire electrode array, the distance between the lower surface of the most advanced and sophisticated and described electrode cap of the described wire electrode that the lower surface of electrode cap described in distance between two tips is nearest is the first distance；
In many described wire electrodes of each described wire electrode array, the distance between the lower surface of the most advanced and sophisticated and described electrode cap of the described wire electrode that the lower surface of electrode cap described in distance between two tips is farthest is second distance；
Difference between described second distance and described first distance is less than or equal to 3mm.
Implanted brain electrode the most according to claim 2, it is characterised in that
The tip of many described wire electrodes of each described wire electrode array is in the same plane.
Implanted brain electrode the most according to claim 1, it is characterised in that
Every described wire electrode includes tinsel and the insulating barrier being arranged on described part perisporium wiry.
Implanted brain electrode the most according to claim 4, it is characterised in that
Described tinsel is made up of platinumiridio or nichrome；
Described insulating barrier is made up of Formvar biocompatibility insulant.
Implanted brain electrode the most according to claim 1, it is characterised in that
The described wire electrode that the monocular district of described muroid brain carries out EEG measuring is arranged such that to be uniformly distributed in the monocular district of described muroid brain；
The described wire electrode that the binocular district of described muroid brain carries out EEG measuring is arranged such that to be uniformly distributed in the binocular district of described muroid brain.
Implanted brain electrode the most according to claim 1, it is characterised in that also include:
Electrode box, described electrode cap is installed in described electrode box, and described electrode box is stretched out at the tip of every described wire electrode.
Implanted brain electrode the most according to claim 7, it is characterised in that described electrode box includes:
Box body, it has base plate and the first side plate, and the lower surface of described electrode cap is installed on the upper surface of described base plate, and described one end of described flexible PCB is installed on described first side plate；
Lid, it has top board, two the second relative side plates, and the 3rd side plate being oppositely arranged with described first side plate, and described lid is removably installed in described box body.
Implanted brain electrode the most according to claim 1, it is characterised in that
Quantity to the described wire electrode that the monocular district of described muroid brain carries out EEG measuring is 8；
Quantity to the described wire electrode that the binocular district of described muroid brain carries out EEG measuring is 8.
Implanted brain electrode the most according to claim 9, it is characterised in that also include:
Two ground wire electrode silks being used as ground wire, every described ground wire electrode silk vertically extends and is installed on the lower surface of described electrode cap, and electrically connect with the bottom passageway of described electrode cap, and has the structure identical with described wire electrode.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620313921.8U CN205586001U (en) | 2016-04-15 | 2016-04-15 | Be used for electrometric implanted brain electrode of muroid brain primary vision cortex brain |
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| CN201620313921.8U CN205586001U (en) | 2016-04-15 | 2016-04-15 | Be used for electrometric implanted brain electrode of muroid brain primary vision cortex brain |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105852855A (en) * | 2016-04-15 | 2016-08-17 | 郑州科斗创客科技有限公司 | Implantable cerebral electrode for measuring cerebral primary visual electrocorticograms in rodents |
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2016
- 2016-04-15 CN CN201620313921.8U patent/CN205586001U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105852855A (en) * | 2016-04-15 | 2016-08-17 | 郑州科斗创客科技有限公司 | Implantable cerebral electrode for measuring cerebral primary visual electrocorticograms in rodents |
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Legal Events
| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170313 Address after: 215132 Jiangsu City, Xiangcheng District Province, Huangqiao street, Sun Road, No. 160, headquarters economic Park A12 building, Patentee after: KEDOU (SUZHOU) BC TECHNOLOGY CO.,LTD. Address before: 450001 Henan Province, Zhengzhou hi tech District, long road, No. 11 National University Science and Technology Park, building No. 2, block B, floor 17 Patentee before: ZHENGZHOU KEDOU CHUANGKE TECHNOLOGY Co.,Ltd. |
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| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160921 |
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| CF01 | Termination of patent right due to non-payment of annual fee |