CN205574438U - Broken leakproofness test tube subassembly of managing mechanism and including this broken pipe mechanism - Google Patents
Broken leakproofness test tube subassembly of managing mechanism and including this broken pipe mechanism Download PDFInfo
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- CN205574438U CN205574438U CN201620194472.XU CN201620194472U CN205574438U CN 205574438 U CN205574438 U CN 205574438U CN 201620194472 U CN201620194472 U CN 201620194472U CN 205574438 U CN205574438 U CN 205574438U
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Abstract
The utility model discloses a broken leakproofness test tube subassembly of managing mechanism and including this broken pipe mechanism. The utility model discloses a broken pipe mechanism is including punctureing part and support part spare, it includes the body and reduces the portion to puncture the part, the center of punctureing the relative support part spare of lateral surface of part or support part spare is asymmetric distribution. The utility model discloses a leakproofness test tube subassembly is including broken pipe mechanism, solution pipe and sleeve pipe, forms the bottom space of sealed gomphosis in the solution pipe gomphosis inserted casing, and broken pipe mechanism is located and just is used for punctureing the bottom that solution was managed with solution socle troops under one's command side of sleeve pipe gomphosis, solution socle portion is pricked the back, and the lateral surface of broken pipe mechanism forms two space passageways with the ruptured entrance to a cave of solution socle portion at least, and the intraductal outflow of solution can be followed to the intraductal solution of solution, and overlapping intraductal air, can to get into solution intraductal. The utility model discloses a broken pipe mechanism can puncture the solution pipe very conveniently, leakproofness test tube subassembly can not produce the leakage, uses extensively, and is effectual.
Description
Technical field
This utility model relates to chromatographic test paper detection device, a kind of Po Guan mechanism, the sealing test tube assembly including this Po Guan mechanism and application thereof.
Background technology
Charlton is in Sidestream chromatography reagent paper technology (the Lateral Flow of invention in 1988, US6485982) immunology diagnosis revolution has been caused, this diagnostic techniques simplifies sample by the way of chromatographic test paper and adds step, passes through the solid-phase immunity reaction on nitrocellulose filter simultaneously and achieves unprecedented simple, quickly, accurately and inexpensively.Colloidal gold immune chromatography test is generalized to widely used fast medical external diagnosis reagent subsequently, has the most also been generalized to food safety and bio-safety field of fast detection.Other Dry-type biochemical reagent paper also begin to use chromatographic test paper mode simultaneously.In the detection project of these chromatographic test papers, part detectable substance confrontation operator and environment can produce damaging effect, such as anthrax Pathogen test, dioxin etc..The chromatography detecting test paper of the most this kind of detection object needs supporting closed detection device.
The most common chromatographic test paper typically uses hand-held test strips and plastics cartridge two kinds of forms of packaging.The production technology of hand-held test strips is simple, and packaging volume is little, stores convenient transportation.It has only in use by the sample solution of an insertion certain depth of regulation, and solution chromatography the most automatically climbs up test strips, demonstrates result in relatively short period of time.But after having detected, whole test strips being substantially filled with the sample solution of residual, this residual solution may pollute environment and operator in subsequent operation.Main the detecting the urine liking human or animal of immune chromatography test paper of the most currently used hand-held test strips form, has communicable clinical sample and does not the most adopt in this way.
The chromatographic test paper product of plastics cartridge packaging is the main flow of existing market.Typically having three kinds of perforates in plastics cartridge, one is sample viewing window, is used for observing the reaction result of chromatographic test paper;One is sample solution added holes;A kind of is that air-vent is for carrying out the sample solution on rapid draing reagent paper.The sample solution being added on reagent paper may be exposed in atmosphere by these three perforate, may pollute environment and operator.But compare hand-held test strips, greatly reduce opportunities for contamination.
American I nverness company employ a kind of detect urine sample early pregnancy pen type plastics cartridge, the observation window of this kind of cartridge is replaced by LCDs or transparent sealed plastic sheet, the added holes of sample solution is replaced by automatic solution absorbing rod, and after sample solution enters absorbing rod, this absorbing rod can be connected by a plastic sheath set, can be sealed in inside plastics cartridge by sample solution completely.
During the urine that current chromatographic test paper is widely used in drug addict quickly detects.Illicit drugs inspection chromatographic test paper predominantly detect the plastics cartridge that reagent paper packaged form is plug-in type headgear.In this packaged form, chromatographic test paper all (containing observation window) can be sealed by transparent plastic sheet, sample interpolation part is stretched out for inserting solution pipette samples, having a plug-in type headgear sample interpolation part of reagent paper to be entangled after sample has been drawn, the most this kind of plastics cartridge can completely cut off the sample solution containing Poison substantially to environment and the pollution of operator.
From Cetus company of U.S. polymerase chain reaction (Polymerase Chain Reaction in 1985, PCR) since realizing the specific amplification of nucleic acid, this technology just because of have high sensitivity, high specific and efficiently feature be widely used in epidemic disease Pathogen test field.But the high concentration cause of disease nucleotide sequence being amplified is easy to contaminated air, test tool and water during subsequent operation, thus results in the false positive results of subsequent detection sample.Therefore in the penetration and promotion of detection of nucleic acids, it is also desirable to develop closed detection apparatus and method.
Solve the nucleic acid amplification product pollution problem when detection, mainly have two kinds of strategies.The first is to build airtight environment during detection nucleic acid amplification product, as: electrophoresis is carried out in airtight negative pressure room, the overall process of real-time fluorescence PCR is not switched on reaction tube, but these methods are required for strict experiment condition and expensive experimental facilities, are not suitable for being popularized for basic unit user.The second is incorporation dUTP in nucleic acid amplification reaction, after react and next time use UNG ferment treatment test tool and environment before nucleic acid amplification, but this method complex operation, and there is certain contamination probability, limit the application of this strategy.
Sidestream chromatography technology is applied in the detection of nucleic acid amplification product by Gerdes etc. (US2004/0110167), brings hope to detection of nucleic acids in basic unit's application.Polluting in order to avoid producing during nucleic acid Sidestream chromatography, optimal selection is to use device to be closed by chromatography process.Look after one's family and forever wait (CN1888902) to invent a kind of closed nucleic acid Sidestream chromatography detection device, its structure includes shell and inner box, inner box includes chromatographing diluent, nucleic acid amplification product and chromatograph test strip, the blade pierces diluted liquid tube in inner box and nucleic acid amplification pipe while shell is closed, the sample pad of chromatograph test strip it is imported into, it is achieved immunochromatography chromogenic reaction after two kinds of liquid mixing.But the shortcoming of this device is: 1, device volume is big, is not suitable for large-scale production and the transport of finished product;2, the test strips in device installs complexity, is not suitable for the reagent paper Assembling Production of scale;3, after this device restarts use, the most simply and can not reopened with having vestige, therefore simply relatively achieve the closing of nucleic acid amplification product, if being not intended to by people open the device reacted, the pollution of amplified production is the most inevitable;4, this device can be only done the detection of single reactant liquor, and multiple reactant liquor cannot be detected, in the way of multiple reactant liquors, i.e. cannot complete the detection of multiple sample in a test strips.
Disclosing a kind of enclosed chromatographic test paper detection device in Chinese invention patent application CN103529201A, this device can realize completely enclosing, and can block the harm to operator of the sample of chromatographic test paper and the pollution of environment completely.But the shortcoming that this device exists has: 1, when solution conduit caliber is less, be difficult to be opened at the bottom of the pipe of solution conduit;2, the gas in connecting tube is not easily accessed solution conduit, causes the gas pressure in connecting tube to raise;If the gas pressure in connecting tube exceedes the air pressure outside pipe, and this pressure differential has exceeded the bearing value sealing structure, and the gas in pipe still can outwards be drained, and when there being solution in pipe, solution also can produce leakage under the driving of gas.
Utility model content
The purpose of this part is summarize some aspects of embodiment of the present utility model and briefly introduce some preferred embodiments.Make a summary in this part and the description of the present application and denomination of invention may be done a little simplification or omit to avoid making the purpose of this part, specification digest and denomination of invention to obscure, and this simplification or omission cannot be used for limiting scope of the present utility model.
In view of above-mentioned and/or problems of the prior art, it is proposed that this utility model.
Therefore, one of them purpose of this utility model is to provide a kind of Po Guan mechanism easily punctured bottom solution conduit.
For solving above-mentioned technical problem, according to an aspect of the present utility model, this utility model provides following technical scheme: a kind of Po Guan mechanism, including rupture component and holding components;Described rupture component include body and be arranged on described body one end reduce portion;Described holding components clamps the body of described rupture component from bottom to top, and described holding components to the portion that reduces of described rupture component in the shape gradually drawn in;The lateral surface of described rupture component or described holding components includes at least two planes, and this lateral surface is mal-distribution relative to the center of holding components.
As a kind of preferred version of the present utility model, wherein: the bottom of described holding components is provided with fitting connection structure, the bottom of described fitting connection structure uses hollow post holes upwards or downward protruding post;Described holding components and described fitting connection structural integrity molding;The hardness of described rupture component material is not less than the hardness of described holding components material;The portion that reduces of described rupture component uses blade or pointed body.
Another purpose of this utility model is to provide a kind of sealing test tube assembly including easily puncturing the Po Guan mechanism bottom solution conduit.
For solving above-mentioned technical problem, according to an aspect of the present utility model, this utility model provides following technical scheme: a kind of sealing test tube assembly including Po Guan mechanism, described sealing test tube assembly includes described Po Guan mechanism, solution conduit and seals chimeric sleeve pipe with described solution conduit, described solution conduit is fitted together in inserting described sleeve pipe to be formed and seals chimeric bottom space, and described Po Guan mechanism is positioned at the solution conduit bottom part down chimeric with described sleeve pipe and for puncturing the bottom of described solution conduit;After being punctured bottom described solution conduit, the hole ruptured bottom the lateral surface of Po Guan mechanism and solution conduit at least forms two interstitial channels, and the solution in solution conduit can flow out in described solution conduit, and the air in sleeve pipe can enter in described solution conduit;Described Po Guan mechanism is fitted and fixed with in described sleeve pipe or one-body molded with described sleeve pipe.
As a kind of preferred version of the present utility model, wherein: described solution conduit outer wall uses the conical surface with described internal surface of sleeve pipe or the face of cylinder coordinates and is provided with at least one pair of back-off embedded structure at the composition surface of the described conical surface or face of cylinder cooperation;Described back-off embedded structure includes bulge loop and the groove matched;After described solution conduit inserts described sleeve pipe, described bulge loop forms back-off with described groove and mates, and causes described solution conduit to be difficult to extract in described sleeve pipe.
As a kind of preferred version of the present utility model, wherein: described solution conduit outer wall uses the conical surface with described internal surface of sleeve pipe or the face of cylinder coordinates and is provided with at least one at the composition surface of the described conical surface or face of cylinder cooperation seals coupling circle;The described coupling circle that seals at least includes a bulge loop, and matched another face of bulge loop forms a certain amount of interference fit, thus plays sealing function;Described sealing is mated at circle or is provided with exhaust gear on described sleeve pipe;When described solution conduit inserts described sleeve pipe, described exhaust gear is by the air communication inside and outside described sleeve pipe, to maintain the suitable gas pressure of described cannula cavity;Described exhaust gear includes the vertical groove on the downside of enclosing in coupling circle that seals being arranged on described the top with the interference of the tube side wall that bulge loop mates coupling, has certain distance between two ends up and down and the interference fit circle of this vertical groove.
As a kind of preferred version of the present utility model, wherein: described solution conduit be internally provided with vertical partition wall, the inside of described solution conduit is divided into two cavitys by described partition wall.
As a kind of preferred version of the present utility model, wherein: the bottom of described solution conduit sets effigurate cut channel, it is simple to the portion that reduces of Po Guan mechanism punctures the bottom of described solution conduit.
As a kind of preferred version of the present utility model, wherein: the bottom of described solution conduit is fitted together to another outward flange and is not more than the solution container of external diameter bottom solution conduit, when thorn upwards pushes up in Po Guan mechanism, first puncture the upper lower wall of described solution container, then puncturing the bottom of solution conduit, the solution of the most described solution container flows out with the solution of solution conduit and mixes.
As a kind of preferred version of the present utility model, wherein: described solution conduit includes body and lid;After described lid press-in solution conduit body, solution conduit inboard wall of tube body and lid outer wall are formed to seal and combine;Described solution conduit inboard wall of tube body uses the conical surface or the face of cylinder to coordinate with lid outer wall;It is provided with at least one pair of back-off embedded structure at the composition surface that the described conical surface or the face of cylinder coordinate;Described back-off embedded structure includes bulge loop and the groove matched;After lid inserts solution conduit body, described bulge loop forms back-off with described groove and mates, and causes described lid to be difficult to extract in solution conduit body.
As a kind of preferred version of the present utility model, wherein: described solution conduit inboard wall of tube body uses the conical surface or the face of cylinder to coordinate with lid outer wall;It is provided with at least one at the composition surface that the described conical surface or the face of cylinder coordinate and seals coupling circle;The described coupling circle that seals at least includes a bulge loop, and matched another face of bulge loop forms a certain amount of interference fit, thus plays sealing function.
As a kind of preferred version of the present utility model, wherein: described sleeve pipe includes connecting tube and matched long tube, described connecting tube uses the conical surface or the face of cylinder to coordinate with described long tube, is provided with at least one pair of back-off embedded structure or at least one seals coupling circle at the chimeric composition surface that the described conical surface or the face of cylinder coordinate;Described back-off embedded structure includes bulge loop and the groove matched, and after described long tube inserts described connecting tube, described bulge loop forms back-off with described groove and mates, and causes described long tube to be difficult to extract in described connecting tube;The described coupling circle that seals at least includes a bulge loop, and matched another face of bulge loop forms a certain amount of interference fit, thus plays sealing function;It is provided with exhaust gear on described long tube;When described solution conduit inserts described connecting tube, described exhaust gear is by the air communication inside and outside described connecting tube, to maintain the described suitable gas pressure of connecting tube inner chamber.
As a kind of preferred version of the present utility model, wherein: described exhaust gear includes that the threaded endoporus being arranged on described long tube and one can be by the screws of this threaded interior hole screwing hermetic;Described screw comprises screw terminal and screw cylinder, and when the revolving force that this screw terminal is exceeded necessarily torsion torch screws, screw terminal departs from the fracture of screw cylinder, and screw column delay is fixed in the threaded interior hole sealed up.
As a kind of preferred version of the present utility model, wherein: described exhaust gear includes that the band being arranged on described long tube seals the endoporus of back-off structure and a plastic closure that this endoporus can carry out back-off sealing;After plastic closure is inserted endoporus, this endoporus is sealed by back-off.
Another purpose of this utility model is to provide the application of a kind of sealing test tube assembly.
For solving above-mentioned technical problem, according to an aspect of the present utility model, this utility model provides following technical scheme: the application of a kind of sealing test tube assembly, described sleeve pipe comprises the medium absorbing described solution conduit release solution, in described solution conduit, the solution of release can occur biochemical reaction on the medium further, presents reaction signal;Described medium uses the one in immune chromatography test paper, the biochemical reagent paper of dry type, certain biochemical reaction composition dried or special bio-chemical solution.
As a kind of preferred version of the present utility model, wherein: comprise particular medium in described long tube, in solution conduit described in described Absorption of Medium, there is biochemical reaction, present reaction signal in the solution of release the most further;Described medium uses the one in immune chromatography test paper, the biochemical reagent paper of dry type, certain biochemical reaction composition dried or special bio-chemical solution.
This utility model has following technical effect that the Po Guan mechanism in this utility model, owing to comprising asymmetrically distributed two sides, can form two passages, make the air pressure balance inside and outside solution conduit, therefore, it can puncture easily solution conduit when puncturing solution conduit;Sealing test tube assembly in this utility model, owing to comprising above-mentioned Po Guan mechanism, therefore can ensure that the air pressure balance inside and outside solution conduit, will not produce leakage;Sealing test tube assembly in this utility model is widely used, and is quick on the draw, effective.
Accompanying drawing explanation
In order to be illustrated more clearly that the technical scheme of this utility model embodiment, in describing embodiment below, the required accompanying drawing used is briefly described, apparently, accompanying drawing in describing below is only embodiments more of the present utility model, for those of ordinary skill in the art, on the premise of not paying creative work, it is also possible to obtain other accompanying drawing according to these accompanying drawings.Wherein:
Fig. 1 is the perspective view of the Po Guan mechanism in this utility model.
Fig. 2 is the perspective view at another visual angle of Po Guan mechanism in this utility model.
Fig. 3 is the front view of the Po Guan mechanism in this utility model.
Fig. 4 is the A-A sectional view in Fig. 3.
Fig. 5 is the top view of Fig. 3.
Fig. 6 is the upward view of Fig. 3.
Fig. 7 is the perspective view of sealing test tube the first embodiment of assembly in this utility model.
Fig. 8 is the front view of sealing test tube the first embodiment of assembly in this utility model.
Fig. 9 is the B-B sectional view in Fig. 8.
Figure 10 is the C-C sectional view in Fig. 8.
Figure 11 is the D-D sectional view in Fig. 8.
Figure 12 is the top view of Fig. 8.
Figure 13 is the E-E sectional view in Figure 12.
Figure 14 is the structural representation sealing coupling circle in this utility model.
Figure 15 is the perspective view of the solution conduit in this utility model.
Figure 16 is the front view of the solution conduit in this utility model.
Figure 17 is the front sectional view of the solution conduit in this utility model.
Figure 18 is the left view of Figure 16.
Figure 19 is the structural representation being provided with solution container in this utility model bottom solution conduit.
Figure 20 is the perspective view of the sealing test tube assembly the second embodiment in this utility model.
Figure 21 is the front sectional view of the sealing test tube assembly the second embodiment in this utility model.
Figure 22 is the perspective view of the exhaust gear the second embodiment in this utility model.
Figure 23 is the front sectional view of Figure 22.
Figure 24 is the perspective view of the third embodiment of exhaust gear in this utility model.
Figure 25 is the front sectional view of Figure 24.In Fig. 1 Figure 19, reference is respectively as follows: Po Guan mechanism 100, rupture component 110, body 111, reduce portion 112, holding components 120, it is fitting to connection structure 121, hollow post holes 122, sealing test tube assembly 200, solution conduit 300, lid 301, partition wall 302, body 303, sleeve pipe 400, connecting tube 410, long tube 420, threaded endoporus 421, screw 422, band seals the endoporus 423 of back-off structure, lid 424, back-off embedded structure 500, bulge loop 501, groove 502, seal coupling circle 600, bulge loop 601, exhaust gear 700, vertical groove 701, solution container 800.
Detailed description of the invention
Understandable for enabling above-mentioned purpose of the present utility model, feature and advantage to become apparent from, below in conjunction with Figure of description, detailed description of the invention of the present utility model is described in detail.
Elaborate a lot of detail in the following description so that fully understanding this utility model, but this utility model can also use other to be different from alternate manner described here to be implemented, those skilled in the art can do similar popularization in the case of this utility model intension, and therefore this utility model is not limited by following public specific embodiment.
Secondly, " embodiment " or " embodiment " referred to herein refers to may be included in special characteristic, structure or the characteristic at least one implementation of this utility model.Different in this manual local " in one embodiment " occurred not refer both to same embodiment, are not single or the most mutually exclusive with other embodiments embodiment.
Understandable for enabling above-mentioned purpose of the present utility model, feature and advantage to become apparent from, below in conjunction with Figure of description, detailed description of the invention of the present utility model is described in detail.
Fig. 1 Fig. 6 is the embodiment representing the Po Guan mechanism 100 in this utility model.Po Guan mechanism 100 is separately as a part.
As shown in Fig. 1 Fig. 6, a kind of Po Guan mechanism 100, including rupture component 110 and holding components 120.The hardness of rupture component 110 material is not less than the hardness of holding components 120 material.
Rupture component 110 includes body 111 and is arranged on the portion that reduces 112 of body 111 one end.The portion that reduces 112 of rupture component 110 uses blade or pointed body.
Holding components 120 clamps the body 111 of rupture component 110 from bottom to top, and holding components 120 to the portion that reduces 112 of rupture component 110 in the shape gradually drawn in.The bottom of holding components 120 is provided with fitting connection structure 121, and the bottom being fitting to connection structure 121 uses hollow post holes 122 upwards or downward protruding post, and the embodiment shown in figure uses hollow post holes 122.Holding components 120 is the most one-body molded with fitting connection structure 121.
The lateral surface of rupture component 110 or holding components 120 includes at least two planes, such as first shown in Fig. 4 A and second B, and the two face A with B is mal-distribution relative to the center of holding components 120, that is, A with B projection of shape on the top view shown in Fig. 5 in the two face is unequal with area, thus when puncturing solution conduit 300, form two passages differed in size based on two asymmetric both sides, as shown in Figure 13.
Fig. 7 Figure 13 is the embodiment representing a kind of sealing test tube assembly 200 using above-mentioned Po Guan mechanism 100.
As shown in Fig. 7 Figure 13, sealing test tube assembly 200 includes Po Guan mechanism 100, solution conduit 300 and seals chimeric sleeve pipe 400 with solution conduit 300.
As shown in Figure 15 Figure 18, solution conduit 300 includes body 303 and lid 301.Connected by connection strap between solution conduit body 303 and lid 301.Solution conduit body 303 is divided into bottom, bottom and top, and the diameter on solution conduit body 303 top is more than the diameter of solution conduit body 303 bottom.Solution conduit body 303 lower, outer perimeter is provided with solution conduit exterior groove 502 or bulge loop, and solution conduit body 303 upper inside wall circumference is provided with solution conduit interior grooves 502 or bulge loop;The periphery of solution conduit lid 301 is provided with solution conduit lid periphery bulge loop 501 or groove.Solution conduit body 303 includes solution conduit exterior groove 502 or bulge loop, solution conduit interior grooves 502 or bulge loop from bottom to up.
As shown in figure 17, being provided with solution conduit polycrystalline substance bottom solution conduit body 303, in the present embodiment, this solution conduit polycrystalline substance is set to the planar structure closed.The bottom of solution conduit 300 is also provided with the cut channel of definite shape, it is simple to the portion that reduces 112 of Po Guan mechanism 100 punctures the bottom of solution conduit 300.This cut channel shape both can be ring or abnormity Guan Bi circle, it is also possible to is ring or the abnormity Guan Bi circle of breach, it is also possible to be the groove of strip.
Requiring there are two solution cavitys for some special biochemical reaction, for reaching this purpose, at the vertical partition wall 302 that is internally provided with of solution conduit 300, as shown in figure 13, the inside of solution conduit 300 is divided into two cavitys by partition wall 302.After completion of the reaction, the solution of two cavitys can be mixed by rocking of solution conduit 300;The solution of two cavitys can also be made to be mixed together when discharging when rupture component 110 cuts through bottom solution conduit 300 simultaneously.
Using the solution in two cavitys of partition wall 302 formation is conjuncted after all, and in course of reaction, some reaction condition cannot independently apply.Therefore, as shown in figure 19, another outward flange can also be fitted together in the bottom of solution conduit 300 and be not more than the solution container 800 of external diameter bottom solution conduit 300, when thorn upwards pushes up in Po Guan mechanism 100, first puncture the upper lower wall of solution container 800, then puncturing the bottom of solution conduit 300, hereafter the solution of solution container 800 flows out with the solution of solution conduit 300 and mixes.
As shown in Figure 12,13, sleeve pipe 400 is provided with a counterbore shape interface mated with solution conduit 300, it is provided with bulge loop or groove in this counterbore shape interface, this bulge loop or groove can coordinate fixing formation back-off embedded structure with the solution conduit exterior groove inserting counterbore shape interface or bulge loop, form sealed environment and can not be opened.
Po Guan mechanism 100 is positioned at solution conduit 300 bottom part down chimeric with sleeve pipe 400 and for puncturing the bottom of solution conduit 300.Po Guan mechanism 100 is fitted and fixed with in sleeve pipe 400 or one-body molded with sleeve pipe 400 by being fitting to connection structure 121.
After being punctured bottom solution conduit 300, the hole ruptured bottom the lateral surface of Po Guan mechanism 100 and solution conduit 300 forms at least two interstitial channels, solution in solution conduit 300 can be flowed out by one of them interstitial channels in solution conduit 300, and the air in sleeve pipe 400 can be entered in solution conduit 300 by other in which interstitial channels.
Solution conduit 300 is chimeric inserts the bottom space that sleeve pipe 400 interior formation sealing is chimeric, and solution conduit 300 outer wall uses the conical surface or the face of cylinder to coordinate with sleeve pipe 400 inwall.
A kind of embodiment at composition surface that the conical surface or the face of cylinder coordinate is provided with at least one pair of back-off embedded structure 500, such as Fig. 9, shown in 13.Back-off embedded structure 500 includes bulge loop 501 and the groove 502 matched.After solution conduit 300 inserts sleeve pipe 400, bulge loop 501 forms back-off with groove 502 and mates, and causes solution conduit 300 to be difficult to extract in sleeve pipe 400.
The another kind of embodiment at composition surface that the conical surface or the face of cylinder coordinate is provided with at least one and seals coupling circle 600, as shown in figure 14.Sealing coupling circle and 600 at least include a bulge loop 601, matched another face of bulge loop 601 forms a certain amount of interference fit, thus plays sealing function.
Seal and be provided with exhaust gear 700 at coupling circle 600.When solution conduit 300 inserts sleeve pipe 400, exhaust gear 700 is by the air communication inside and outside sleeve pipe 400, to maintain the sleeve pipe 400 suitable gas pressure of inner chamber.
The first embodiment of exhaust gear 700, including the vertical groove 701 on the downside of mating circle with the interference of the tube side wall that bulge loop 601 mates in coupling circle 600 that seals being arranged on topmost, has certain distance between two ends up and down and the interference fit circle of this vertical groove 701.
As shown in figure 17, solution conduit body 303 upper inside wall circumference is provided with upper and lower two grooves 502 or bulge loop, it is internal first groove of solution conduit or bulge loop, internal second groove of solution conduit or bulge loop respectively, the periphery of solution conduit lid 301 is provided with bulge loop 501 or groove, and this solution conduit lid periphery bulge loop 501 or groove first groove internal with solution conduit or bulge loop, internal second groove of solution conduit or bulge loop can fitted seal.See Figure 13, solution conduit lid periphery bulge loop or groove and coordinate with solution conduit interior grooves or bulge loop fixing.When being groove 502 on solution conduit body 303 upper inside wall circumference, then the periphery of solution conduit lid 301 is bulge loop 501;Otherwise, when being bulge loop 501 groove 502 on solution conduit body 303 upper inside wall circumference, then the periphery of solution conduit lid 301 is groove 502.Solution conduit lid 301 solution conduit lid periphery bulge loop or groove first first groove internal with solution conduit or bulge loop during covering coordinate, after second time pressing, solution conduit lid 301 can also press LAP second groove internal with solution conduit again or bulge loop coordinates, and the state that finally covers is in extracting and sealing state (internal liquid will not occur leakage phenomenon).Internal first groove of solution conduit or bulge loop can allow solution conduit lid 301 to repeat to open, and solution conduit lid 301 lived by internal second groove of solution conduit or bulge loop then reverse barb so that it is form enclosed environment after being disposably pressed into position, it is impossible to be opened again.
Solution conduit body 303 inwall uses the conical surface or the face of cylinder to coordinate with lid 301 outer wall.After lid 301 is pressed into solution conduit body 303, solution conduit body 303 inwall and lid 301 outer wall are formed to seal and combine.
In some applications, it is desirable to the solution in solution conduit 300 is after bottom is discharged into sleeve pipe 400, and solution conduit 300 and sleeve pipe 400 still maintain one to seal cavity, therefore it is required that solution conduit 300 and its lid 301 sealing to be formed back-off structure.
A kind of embodiment sealing back-off structure is: be provided with at least one pair of back-off embedded structure 500 at the composition surface that the conical surface or the face of cylinder coordinate;Back-off embedded structure 500 includes bulge loop 501 and the groove 502 matched;After lid 301 inserts solution conduit body 303, bulge loop 501 forms back-off with groove 502 and mates, and causes lid 301 to be difficult to extract in solution conduit body 303.
The another embodiment sealing back-off structure is: is provided with at least one at the composition surface that the conical surface or the face of cylinder coordinate and seals coupling circle 601, as shown in figure 14.Sealing coupling circle and 601 at least include a bulge loop 601, matched another face of bulge loop 601 forms a certain amount of interference fit, thus plays sealing function.
As shown in Figure 20, Figure 21, sleeve pipe 400 includes connecting tube 410 and matched long tube 420.Connecting tube 410 is provided with a counterbore shape interface mated with solution conduit 300, it is provided with bulge loop or groove in this counterbore shape interface, this bulge loop or groove can coordinate fixing formation back-off embedded structure with the solution conduit exterior groove inserting interface or bulge loop, form sealed environment and can not be opened.
Counterbore shape interface inner bottom part is provided with Po Guan mechanism 100, and for discharging the solution in solution conduit, it gives specific function power and can be ruptured disengaging solution conduit polycrystalline substance, and solution discharges from solution conduit.The inner bottom part of counterbore shape interface is provided with solution channel, the liquid that solution conduit discharges will flow to long tube 420 through solution channel in the sample solution reception area of chromatographic test paper.In the present embodiment, Po Guan mechanism 100 inserts and is entrenched in the pit of connecting tube 410 counterbore shape interface inner bottom part.
An interface mated with long tube 420 it is additionally provided with in connecting tube 410, bulge loop or groove it is provided with in this interface, this bulge loop or groove coordinate fixing with long tube 420 exterior groove or bulge loop, form back-off and seal structure, be inserted into after making stress and form sealed environment after the long tube 420 of connecting tube 410 enters position and can not be opened.
Long tube 420 is the hollow tube of one end open.Mating at the long tube 420 inserting connecting tube 410 and be additionally provided with exterior groove or bulge loop on position, this exterior groove or bulge loop are fixed with the bulge loop in connecting tube 410 or groove fit, and reagent paper is inserted by long tube 420 opening part.
Connecting tube 410 uses the conical surface or the face of cylinder to coordinate with long tube 420, is provided with at least one pair of back-off embedded structure 500 or at least one seals coupling circle 601 at the chimeric composition surface that the conical surface or the face of cylinder coordinate.
Back-off embedded structure 500 includes bulge loop 501 and the groove 502 matched, and after long tube 420 inserts connecting tube 410, bulge loop 501 forms back-off with groove 502 and mates, and causes long tube 420 to be difficult to extract in connecting tube 410.
Sealing coupling circle and 601 at least include a bulge loop 601, matched another face of bulge loop 601 forms a certain amount of interference fit, thus plays sealing function, as shown in figure 14.
Exhaust gear 700 it is provided with on long tube 420;When solution conduit 300 inserts connecting tube 410, exhaust gear 700 is by the air communication inside and outside connecting tube 410, to maintain the connecting tube 410 suitable gas pressure of inner chamber.
The second embodiment of exhaust gear 700, can be by the screw 422 of this threaded interior hole 421 screwing hermetic including the threaded endoporus of be arranged on long tube 420 421 and one;Screw thread comprises screw terminal and screw cylinder, and when the revolving force that this screw terminal is exceeded necessarily torsion torch screws, screw terminal departs from the fracture of screw cylinder, and screw column delay is fixed in the threaded interior hole sealed up.
The third embodiment of exhaust gear 700, including endoporus 423 and the plastic closure 424 that this endoporus 423 can carry out back-off sealing of the band sealing back-off structure being arranged on long tube 420;After plastic closure 424 is inserted endoporus 423, this endoporus 423 is sealed by back-off.
As a kind of application of sealing test tube assembly, comprising absorbent solution pipe 300 and discharge the medium of solution in sleeve pipe 400, in solution conduit 300, the solution of release can occur biochemical reaction on the medium further, presents reaction signal.
As the another kind of application of sealing test tube assembly, comprising particular medium in long tube 420, in Absorption of Medium solution conduit 300, there is biochemical reaction, present reaction signal in the solution of release the most further.
In above two application, medium uses the one in immune chromatography test paper, the biochemical reagent paper of dry type, certain biochemical reaction composition dried or special bio-chemical solution.
It should be noted that, above example is only in order to illustrate the technical solution of the utility model and unrestricted, although this utility model being described in detail with reference to preferred embodiment, it will be understood by those within the art that, the technical solution of the utility model can be modified or equivalent, without deviating from the spirit and scope of technical solutions of the utility model, it all should be contained in the middle of right of the present utility model.
Claims (15)
1. a Zhong Poguan mechanism (100), it is characterised in that: include rupture component (110) and holding components (120);Described rupture component (110) includes body (111) and is arranged on the portion that reduces (112) of described body (111) one end;Described holding components (120) clamps the body (111) of described rupture component (110) from bottom to top, and described holding components (120) to the portion that reduces (112) of described rupture component (110) in the shape gradually drawn in;The lateral surface of described rupture component (110) or described holding components (120) includes at least two planes, and this lateral surface is mal-distribution relative to the center of holding components (120).
2. Po Guan mechanism (100) as claimed in claim 1, it is characterized in that: the bottom of described holding components (120) is provided with fitting connection structure (121), the bottom of described fitting connection structure (121) uses hollow post holes (122) upwards or downward protruding post;Described holding components (120) can be one-body molded with described fitting connection structure (121);The hardness of described rupture component (110) material uses blade or pointed body not less than the hardness of described holding components (120) material, the portion that reduces (112) of described rupture component (110).
3. one kind comprises just like claim 1, sealing test tube assembly (200) of the Po Guan mechanism (100) according to any one of 2, described sealing test tube assembly (200) includes described Po Guan mechanism (100), solution conduit (300) and the sleeve pipe (400) chimeric with described solution conduit (300) sealing, it is characterized in that: described solution conduit (300) is chimeric inserts the bottom space that described sleeve pipe (400) interior formation sealing is chimeric, described Po Guan mechanism (100) is positioned at solution conduit (300) bottom part down chimeric with described sleeve pipe (400) and is used for puncturing the bottom of described solution conduit (300);After described solution conduit (300) bottom is punctured, the hole that the lateral surface of Po Guan mechanism (100) ruptures with solution conduit (300) bottom at least forms two interstitial channels, solution in solution conduit (300) can flow out in described solution conduit (300), and the air in sleeve pipe (400) can enter in described solution conduit (300);Described Po Guan mechanism (100) is fitted and fixed with in described sleeve pipe (400) or one-body molded with described sleeve pipe (400).
4. sealing test tube assembly as claimed in claim 3, it is characterised in that: described solution conduit (300) outer wall uses the conical surface with described sleeve pipe (400) inwall or the face of cylinder coordinates and is provided with at least one pair of back-off embedded structure (500) at the composition surface of the described conical surface or face of cylinder cooperation;Described back-off embedded structure (500) includes bulge loop (501) and the groove (502) matched;After described solution conduit (300) inserts described sleeve pipe (400), described bulge loop (501) forms back-off with described groove (502) and mates, and causes described solution conduit (300) to be difficult to extract in described sleeve pipe (400).
5. sealing test tube assembly as claimed in claim 3, it is characterised in that: described solution conduit (300) outer wall uses the conical surface with described sleeve pipe (400) inwall or the face of cylinder coordinates and is provided with at least one sealing coupling circle (600) at the composition surface of the described conical surface or face of cylinder cooperation;Described coupling circle (600) that seals at least includes a bulge loop (601), and matched another face of bulge loop (601) forms a certain amount of interference fit, thus plays sealing function;Described sealing is provided with exhaust gear (700) on coupling circle (600) place or described sleeve pipe (400);When described solution conduit (300) inserts described sleeve pipe (400), described exhaust gear (700) is by the air communication inside and outside described sleeve pipe (400), to maintain the suitable gas pressure of described sleeve pipe (400) inner chamber;Described exhaust gear (700) includes being arranged in sealing coupling circle (600) of described the top and the vertical groove (701) on the downside of the interference of the tube side wall that bulge loop (601) mates coupling circle, has certain distance between two ends up and down and the interference fit circle of this vertical groove (701).
6. sealing test tube assembly as claimed in claim 3, it is characterized in that: described solution conduit (300) be internally provided with vertical partition wall (302), the inside of described solution conduit (300) is divided into two cavitys by described partition wall (302).
7. sealing test tube assembly as claimed in claim 3, it is characterized in that: the bottom of described solution conduit (300) sets effigurate cut channel, it is simple to the portion that reduces (112) of Po Guan mechanism (100) punctures the bottom of described solution conduit (300).
8. sealing test tube assembly as claimed in claim 3, it is characterized in that: the chimeric solution container (800) having another outward flange to be not more than solution conduit (300) bottom external diameter in the bottom of described solution conduit (300), when thorn upwards pushes up in Po Guan mechanism (100), first puncture the upper lower wall of described solution container (800), then puncturing the bottom of solution conduit (300), the solution of the most described solution container (800) flows out with the solution of solution conduit (300) and mixes.
9. sealing test tube assembly as claimed in claim 3, it is characterised in that: described solution conduit (300) includes body (303) and lid (301);After described lid (301) press-in solution conduit body (303), solution conduit body (303) inwall and lid (301) outer wall are formed to seal and combine;Described solution conduit body (303) inwall uses the conical surface or the face of cylinder to coordinate with lid (301) outer wall;It is provided with at least one pair of back-off embedded structure (500) at the composition surface that the described conical surface or the face of cylinder coordinate;Described back-off embedded structure (500) includes bulge loop (501) and the groove (502) matched;After lid (301) inserts solution conduit body (303), described bulge loop (501) forms back-off with described groove (502) and mates, and causes described lid (301) to be difficult to extract in solution conduit body (303).
10. sealing test tube assembly as claimed in claim 9, it is characterised in that: described solution conduit body (303) inwall uses the conical surface or the face of cylinder to coordinate with lid (301) outer wall;It is provided with at least one at the composition surface that the described conical surface or the face of cylinder coordinate and seals coupling circle (600);Described coupling circle (600) that seals at least includes a bulge loop (601), and matched another face of bulge loop (601) forms a certain amount of interference fit, thus plays sealing function.
11. sealing test tube assemblies as claimed in claim 3, it is characterized in that: described sleeve pipe (400) includes connecting tube (410) and matched long tube (420), described connecting tube (410) uses the conical surface or the face of cylinder to coordinate with described long tube (420), is provided with at least one pair of back-off embedded structure (500) or at least one seals coupling circle (600) at the chimeric composition surface that the described conical surface or the face of cylinder coordinate;Described back-off embedded structure (500) includes bulge loop (501) and the groove (502) matched, after described long tube (420) inserts described connecting tube (410), described bulge loop (501) forms back-off with described groove (502) and mates, and causes described long tube (420) to be difficult to extract in described connecting tube (410);Described coupling circle (600) that seals at least includes a bulge loop (601), and matched another face of bulge loop (601) forms a certain amount of interference fit, thus plays sealing function;Exhaust gear (700) it is provided with on described long tube (420);When described solution conduit (300) inserts described connecting tube (410), described exhaust gear (700) is by the air communication inside and outside described connecting tube (410), to maintain the suitable gas pressure of described connecting tube (410) inner chamber.
12. sealing test tube assemblies as claimed in claim 11, it is characterised in that: described exhaust gear (700) includes that the threaded endoporus (421) being arranged on described long tube (420) and one can be by the screws (422) of this threaded interior hole (421) screwing hermetic;Described screw (422) comprises screw terminal and screw cylinder, and when the revolving force that this screw terminal is exceeded necessarily torsion torch screws, screw terminal departs from the fracture of screw cylinder, and screw column delay is fixed in the threaded interior hole (421) sealed up.
13. sealing test tube assemblies as claimed in claim 11, it is characterised in that: the band that described exhaust gear (700) includes being arranged on described long tube (420) seals the endoporus (423) of back-off structure and a plastic closure (424) that this endoporus (423) can carry out back-off sealing;After plastic closure (424) is inserted endoporus (423), this endoporus (423) is sealed by back-off.
The 14. sealing test tube assemblies as according to any one of claim 4-9, it is characterized in that: described sleeve pipe (400) comprises the medium absorbing described solution conduit (300) release solution, in described solution conduit (300), the solution of release can occur biochemical reaction on the medium further, presents reaction signal;Described medium uses the one in immune chromatography test paper, the biochemical reagent paper of dry type, certain biochemical reaction composition dried or special bio-chemical solution.
The 15. sealing test tube assemblies as according to any one of claim 10-13, it is characterized in that: described long tube (420) also can comprise particular medium, the solution of release in solution conduit (300) described in described Absorption of Medium, there is biochemical reaction the most further, present reaction signal;Described medium uses the one in immune chromatography test paper, the biochemical reagent paper of dry type, certain biochemical reaction composition dried or special bio-chemical solution.
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105836240A (en) * | 2016-03-14 | 2016-08-10 | 上海快灵生物科技有限公司 | Tube breaking mechanism, sealed test tube assembly comprising tube breaking mechanism and application thereof |
CN109789410A (en) * | 2016-10-07 | 2019-05-21 | 勃林格殷格翰维特梅迪卡有限公司 | Storage tube for test sample |
WO2020173446A1 (en) * | 2019-02-25 | 2020-09-03 | 上海快灵生物科技有限公司 | Biochemical reaction test strip tube and use method therefor, and kit |
WO2021254512A1 (en) * | 2020-06-19 | 2021-12-23 | 上海快灵生物科技有限公司 | Tube-breaking structure, biochemical test tube and heat-conducting blind tube |
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2016
- 2016-03-14 CN CN201620194472.XU patent/CN205574438U/en active Active
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105836240A (en) * | 2016-03-14 | 2016-08-10 | 上海快灵生物科技有限公司 | Tube breaking mechanism, sealed test tube assembly comprising tube breaking mechanism and application thereof |
CN105836240B (en) * | 2016-03-14 | 2018-08-21 | 上海快灵生物科技有限公司 | Po Guan mechanisms, include the Po Guan mechanisms leakproofness test tube component and its application |
CN109789410A (en) * | 2016-10-07 | 2019-05-21 | 勃林格殷格翰维特梅迪卡有限公司 | Storage tube for test sample |
WO2020173446A1 (en) * | 2019-02-25 | 2020-09-03 | 上海快灵生物科技有限公司 | Biochemical reaction test strip tube and use method therefor, and kit |
WO2021254512A1 (en) * | 2020-06-19 | 2021-12-23 | 上海快灵生物科技有限公司 | Tube-breaking structure, biochemical test tube and heat-conducting blind tube |
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