CN205235469U

CN205235469U - Chromatography column of reinforcing leakproofness

Info

Publication number: CN205235469U
Application number: CN201520978463.5U
Authority: CN
Inventors: 易国军; 汤珊; 汤志敏; 曹灿辉
Original assignee: WUHAN HUIYAN BIOTECHNOLOGY Co Ltd
Current assignee: WUHAN HUIYAN BIOTECHNOLOGY Co Ltd
Priority date: 2015-11-30
Filing date: 2015-11-30
Publication date: 2016-05-18
Anticipated expiration: 2025-11-30

Abstract

The utility model relates to a chromatography column of reinforcing leakproofness, including last end cap, thread bush, go up membrane, column jacket, membrane, screw thread export, end cap and internal thread pipe end down, characterized in that upward the membrane is the double -deck cylinder of stairstepping, upward is provided with the O type sealing washer eager with each facial features in membrane and thread bush, the internal thread curved surface that the pipeline section encloses, is provided with the O type sealing washer of hugging closely with last end cap on the inboard cavity boss of thread bush, and this utility model's beneficial effect is strengthening the leakproofness of chromatography void column, prevents that solution from oozing out, and simple structure, is suitable for industrial production.

Description

A kind of chromatographic column that strengthens sealing

Technical field

The utility model relates to bio-separation purifying experimental apparatus field, is particularly related to a kind of chromatographic column that strengthens sealing.

Background technology

Existingly repeat to install and use chromatography void column, although improved void column utilization ratio, greatly save use cost, but this spiral piston of chromatography void column that repeats to install and use directly contacts with upper film, and when sample introduction, chromatography void column internal pressure is higher, in void column, solution easily sees through upper screen and enters the gap that is threaded under hyperbaric environment, even may from the gap that is threaded, ooze out, pollute, and solution enters the gap that is threaded and also can cause the spiral piston difficulty of back-outing.

Utility model content

Technical problem to be solved in the utility model is to repeat to install and use the sealing problem of chromatography void column.

The technical scheme that the utility model solves the problems of the technologies described above is as follows: a kind of chromatographic column that strengthens sealing,

Comprise upper plug head, thread bush, upper film, internal thread pipe end, column jecket, lower film, threaded outlet and lower end cap, described internal thread pipe end, threaded outlet is fixedly connected on respectively the two ends up and down of column jecket, described internal thread pipe end internal diameter is greater than column jecket internal diameter, described internal thread pipe end and inner side, column jecket junction form step, described thread bush is threaded in internal thread pipe end, described thread bush inside is provided with the cavity that connects upper and lower both ends of the surface, the be threaded upper end open place of cavity of described upper plug head, described lower end cap is threaded in outside threaded outlet, described lower film is positioned at column jecket bottom, described upper film profile is the thick stairstepping double-layer circular cylinder in thin bottom, top, be respectively upper strata cylinder and lower floor's cylinder, described upper strata cylinder contacts with thread bush face, described lower floor cylinder contacts with step surface, between described upper strata cylinder and lower floor's cylinder, be provided with ladder angle face, the ladder angle face of described upper film and internal thread pipe end, in the space that thread bush surrounds, be provided with an O RunddichtringO, described cavity is positioned on the inwall of the part under upper plug head and is provided with boss, on described boss, be provided with and prolong the 2nd O RunddichtringO that cavity inner wall hoop is arranged, upper plug head is tightened posterior end face can compress described the second O-ring seals.

The beneficial effects of the utility model are: after thread bush, upper plug head are tightened, O-ring seals can well be separated solution in column jecket and threaded connection place, prevent that solution from entering threaded connection place and even oozing out, and strengthen the sealing of chromatography void column.

On the basis of technique scheme, the utility model can also do following improvement.

Further, described thread bush and internal thread pipe end adopt taper thread to be connected, and thread bush is connected with upper plug head employing taper thread, and aspect sealing, taper thread is obviously better than straight thread, and taper thread is tightened with to unclamp the required rotation number of turns few, simple to operation.

Further, it is the cylinder that diameter is slightly less than upper strata body diameter that described upper film can be used for filtration fraction, and this structure can further limit the connection scope of solution in void column, prevents that solution from entering the threaded connection place of thread bush and internal thread link.

Further, described internal thread pipe end outside is upper coarse and lower fine truncated cone-shaped, is convenient to card and is placed on chromatography void column holding frame.

Further, described sample introduction tube connector end profiles can be arranged to the same with upper plug head profile, can ensure bonding strength and the sealing of injection port and chromatography void column.

Brief description of the drawings

Fig. 1 is the utility model cutaway view;

Fig. 2 is film cutaway view on the utility model;

Fig. 3 is the utility model sample introduction tube connector end.

In accompanying drawing, the list of parts of each label representative is as follows:

1, upper plug head, 2, the second O-ring seals, 3, thread bush, 4, upper film, 5, internal thread pipe end, the 6, the 1 shape sealing ring, 7, column jecket, 8, lower film, 9, threaded outlet, 10, lower end cap, 11, sample feeding pipe end, 12, sample feeding pipe, 301, cavity, 302, cavity bottom, 303, boss, 401, upper strata cylinder, 402, lower floor's cylinder, 403, ladder angle face, 404, screen area, 501, step.

Detailed description of the invention

Below in conjunction with accompanying drawing, principle of the present utility model and feature are described, example, only for explaining the utility model, is not intended to limit scope of the present utility model.

As shown in Figure 1, a kind of chromatographic column that strengthens sealing, comprise upper plug head 1, the second O-ring seals 2, the first O-ring seals 6, thread bush 3, upper film 4, column jecket 7, lower film 8, threaded outlet 9, lower end cap 10 and internal thread pipe end 5, the upper and lower side of described column jecket 7 respectively with internal thread pipe end 5, threaded outlet 9 is fixedly connected with, internal thread pipe end 5 internal diameters are greater than column jecket 7 internal diameters, internal thread pipe end 5 forms step 501 with column jecket 7 inner sides, junction, described internal thread pipe end 5 is connected in taper thread mode with thread bush 3 external screw threads, the described internal thread pipe end 5 thin truncated cone-shaped in thick lower end, one-tenth upper end, outside, described threaded outlet 9 lower end cap 10 that is threaded, described lower film 8 is positioned at column jecket 7 bottoms, described upper film 4 is stairstepping double-layer circular cylinder, the diameter of upper strata cylinder 401 is less than the diameter of lower floor's cylinder 402, upper strata cylinder 401 contacts with 3 of thread bush, lower floor's cylinder 402 contacts with 501, step, described thread bush 3 inner sides are provided with cavity 301, the top of cavity 301 is provided with screw thread and is connected in taper thread mode with upper plug head 1, described cavity bottom 302 diameters are slightly less than film upper strata cylinder 401 diameters, described cavity 301 is positioned on the inwall of the part under upper plug head 1 and is provided with boss 303, on boss 303, be provided with the 2nd O RunddichtringO 2, upper plug head 1 can compress described the second O-ring seals 2 after tightening, the first O-ring seals 6 is positioned at the ladder angle face 403 and internal thread pipe end 5 of film 4, in the space that thread bush 3 surrounds and with each tangent.

As shown in Figure 2, the screen area 404 of upper film 4 is for being slightly less than the cylinder of upper strata cylinder 401 diameters, and the region beyond the screen area on upper film 4 is compact structure.

As shown in Figure 3, when sample introduction, the cavity of described thread bush 3 inner sides is connected with sample feeding pipe 12, the outer formation taper thread in sample feeding pipe end 11 of sample feeding pipe 12, the same with upper plug head 1 screw thread position shape, sample feeding pipe end 11 is threadedly connected to the top of the cavity 301 of thread bush 3 inner sides, and after sample feeding pipe 12 tightens, O RunddichtringO 2 can be pressed in 11 lower surfaces, sample feeding pipe end.

According to the conventional method filling post material that can repeat to install and use chromatographic column, after threaded together cover 3, upper plug head 1, lower end cap 10, dress post completes, now the 2nd O RunddichtringO 2, an O RunddichtringO 6 are compacted, well solution in void column is sealed in to column jecket 7 inside, prevents that solution from entering the gap that is threaded.

The foregoing is only preferred embodiment of the present utility model, not in order to limit the utility model, all within spirit of the present utility model and principle, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection domain of the present utility model.

Claims

1. one kind strengthens the chromatographic column of sealing, it is characterized in that, comprise upper plug head (1), thread bush (3), upper film (4), internal thread pipe end (5), column jecket (7), lower film (8), threaded outlet (9) and lower end cap (10), described internal thread pipe end (5), threaded outlet (9) is fixedly connected on respectively the two ends up and down of column jecket (7), described internal thread pipe end (5) internal diameter is greater than column jecket (7) internal diameter, described internal thread pipe end (5) forms step (501) with inner side, column jecket (7) junction, described thread bush (3) is threaded in internal thread pipe end (5), described thread bush (3) inside is provided with the cavity (301) that connects upper and lower both ends of the surface, the be threaded upper end open place of cavity (301) of described upper plug head (1), described lower end cap (10) is threaded in outside threaded outlet (9), described lower film (8) is positioned at column jecket (7) bottom, described upper film (4) profile is the thick stairstepping double-layer circular cylinder in thin bottom, top, be respectively upper strata cylinder (401) and lower floor's cylinder (402), described upper strata cylinder (401) contacts with thread bush (3) face, described lower floor cylinder (402) contacts with step (501) face, between described upper strata cylinder (401) and lower floor's cylinder (402), be provided with ladder angle face (403), the ladder angle face (403) of described upper film (4) and internal thread pipe end (5), in the space that thread bush (3) surrounds, be provided with an O RunddichtringO (6), described cavity (301) is positioned on the inwall of the part under upper plug head (1) and is provided with boss (303), on described boss (303), be provided with and prolong the 2nd O RunddichtringO (2) that cavity (301) inwall hoop is arranged, upper plug head (1) is tightened posterior end face can compress described the second O-ring seals (2).

2. the chromatographic column of enhancing sealing as claimed in claim 1, it is characterized in that, the mode that described internal thread pipe end (5) is threaded with thread bush (3) is that taper thread is connected, and the mode that described upper plug head (1) is threaded with the upper end open place of cavity (301) is that taper thread is connected.

3. the chromatographic column of enhancing sealing as claimed in claim 1, it is characterized in that, screen area (404) on described upper film (4) is for being less than the cylinder of upper strata cylinder (401) diameter, and the region in addition of the screen area (404) on described upper film (4) is compact structure.

4. the chromatographic column of the enhancing sealing as described in claim 1-3 any one, is characterized in that, described internal thread pipe end (5) outer shape is the thin truncated cone-shaped in thick lower end, upper end.