CN204395003U - Machine for making small ball type granulating materials - Google Patents

Machine for making small ball type granulating materials Download PDF

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Publication number
CN204395003U
CN204395003U CN201520023591.4U CN201520023591U CN204395003U CN 204395003 U CN204395003 U CN 204395003U CN 201520023591 U CN201520023591 U CN 201520023591U CN 204395003 U CN204395003 U CN 204395003U
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CN
China
Prior art keywords
ball
round
bearing
spheronizator
inner sleeve
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Expired - Fee Related
Application number
CN201520023591.4U
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Chinese (zh)
Inventor
王海龙
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Hebei Jin Dafu Pharmaceutcal Corp Ltd
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Hebei Jin Dafu Pharmaceutcal Corp Ltd
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Priority to CN201520023591.4U priority Critical patent/CN204395003U/en
Application granted granted Critical
Publication of CN204395003U publication Critical patent/CN204395003U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a kind of machine for making small ball type granulating materials, comprise frame, be arranged on the screw extruder of frame top, be arranged on the spheronizator of frame front end and the blower fan supporting with spheronizator that be arranged on bottom frame, and the discharging opening of described screw extruder is positioned at directly over spheronizator hopper; List structure is extruded into after medicine material, excipient and binder combination being mixed by screw extruder, the list structure extruded falls in round as a ball cylinder, under the effect of frictional disk, list structure with roll cylinder inner wall and clash into the section of fragmenting into, and ball-type micropill is formed gradually under the effect of frictional disk, the diameter of microspheric granula can regulate by controlling frictional disk rotating speed, is applicable to the processing of below 1mm ball-type micropill.

Description

Machine for making small ball type granulating materials
Technical field
This utility model relates to a kind of ball-type micropill medicine and prepares equipment technology field, particularly relates to a kind of machine for making small ball type granulating materials.
Background technology
Along with slow release in pharmaceuticals industry, the development of controlled release preparation, the demand of soccer star's micropill of 1 below ㎜ increases increasingly, the preparation method of ball-type micropill is divided into two kinds usually, first method prepares orifice plate ball core as pharmaceutical carrier, multilayer medicine and sustained release film is wrapped in ball wicking surface alternating packets, thus control the release of medicine, another kind method is by medicine material, excipient and binding agent mix homogeneously make micropill, sustained release film is superscribed again on micropill surface, become and there is slow release, the pill of control-release function, these two kinds of micropills all require that roundness is good, intensity is high, not easy disintegrating, be beneficial to coating.
Along with the development that industrial automation is produced, pharmaceuticals industry automaticity improves gradually, existing micropill manufacture mostly adopts vibrating prilling mode to be shaped, though this kind of pelletize mode production efficiency is high, but the micropill not being suitable for processing below 1mm is produced, therefore, manufacturing a kind of automated arm that can be applicable to micropill and produce, is this area urgent problem.
Utility model content
Technical problem to be solved in the utility model is to provide a kind of machine for making small ball type granulating materials; list structure is extruded into after medicine material, excipient and binder combination being mixed by screw extruder; the list structure extruded falls in round as a ball cylinder; under the effect of frictional disk; list structure with roll cylinder inner wall and clash into the section of fragmenting into; and ball-type micropill is formed gradually under the effect of frictional disk; the diameter of microspheric granula can regulate by controlling frictional disk rotating speed, is applicable to the processing of below 1mm ball-type micropill.
For solving the problems of the technologies described above, technical solution adopted in the utility model is: a kind of machine for making small ball type granulating materials, comprise frame, be arranged on the screw extruder of frame top, the spheronizator being arranged on frame front end and the blower fan supporting with spheronizator be arranged on bottom frame, the discharging opening of described screw extruder is positioned at directly over spheronizator hopper, described screw extruder comprises the support be vertically fixedly mounted on above frame, extruder motor, reductor, extrusion screw rod and extruder hopper, described support left surface installs extruded tube by means of pressing plate level, suit extrusion screw rod in extruded tube, the extruder hopper with extruded tube inner space is installed on extruded tube outer wall top, extruded tube end outer wall also arranges coolant jacket, described extruded tube open end is installed by means of gland nut and is extruded orifice plate, one end that described extrusion screw rod is positioned at pressing plate is arranged through the through hole of mid-stent, support right flank fixedly mounts bearing outside, be positioned at the extrusion screw rod of bearing outside by Morse's cone anatomical connectivity bearing inner sleeve, between bearing inner sleeve and bearing outside, bearing is installed, described bearing inner sleeve connects reductor by means of the first shaft coupling, reductor power intake is connected with extruder motor clutch end.
Describedly extrude uniform isodiametric through hole on orifice plate, percent opening is 30%, and the ratio of extrusion cavities plate thickness and through-hole diameter is 3-5:1.
Described spheronizator comprises the vertical round as a ball cylinder arranged, be arranged on the frictional disk in round as a ball cylinder, the spheronizator hopper be arranged on round as a ball cover is vertically arranged on the overcoat in the middle part of round as a ball tube end plate, vertically be arranged on the main shaft in the middle part of frictional disk, the inner sleeve be connected with main shaft lower end and the round as a ball motor be connected with inner sleeve lower end by means of the second shaft coupling, described frictional disk is medial recess, and the disk-like structure that edge is upwards dug, its outer rim with roll cylinder inner wall matched in clearance, described frictional disk is positioned in the middle part of round as a ball cylinder, described outer set upper side is fixedly connected with round as a ball tube end plate, bearing is fixedly mounted between described inner sleeve and overcoat, the fixed installation of described overcoat top and bottom is used for the bearing (ball) cover of pressing bearing, Morse's cone anatomical connectivity is adopted between described main shaft lower end and inner sleeve, described round as a ball tube end plate is also vertically provided with the ajutage with its inner space, described ajutage lower end is communicated with fan outlet.
The beneficial effect adopting technique scheme to produce is: be extruded into list structure after medicine material, excipient and binder combination being mixed by screw extruder, the list structure extruded falls in round as a ball cylinder, under the effect of frictional disk, list structure with roll cylinder inner wall and clash into the section of fragmenting into, and ball-type micropill is formed gradually under the effect of frictional disk, the diameter of microspheric granula can regulate by controlling frictional disk rotating speed, is applicable to the processing of below 1mm ball-type micropill.
Accompanying drawing explanation
Fig. 1 is this utility model structural representation;
Fig. 2 is extruder structure schematic diagram;
Fig. 3 is spheronizator structural representation;
In the accompanying drawings: 1, blower fan; 2, round as a ball motor; 3, the first shaft coupling; 4, cleanout; 5, frictional disk; 6, discharging opening; 7, round as a ball cylinder; 8, spheronizator hopper; 9, gland nut; 10, orifice plate is extruded; 11, extrusion screw rod; 12, extruded tube; 13, extruder hopper; 14, support; 15, the second shaft coupling; 16, reductor; 17, extruder motor; 18, control panel; 19, coolant jacket; 20, bearing outside; 21, bearing inner sleeve; 22, bearing; 23, the first dismounting nut; 24, the second dismounting nut; 25, knob; 26, round as a ball cover; 27, discharge door; 28, bearing (ball) cover; 29, inner sleeve; 30, main shaft; 31, ajutage.
Detailed description of the invention
Below in conjunction with the drawings and specific embodiments, this utility model is described in further detail.
Automatically the problem of 1mm micropill can not be produced in order to solve existing granulating machine, this utility model provides a kind of machine for making small ball type granulating materials as shown in Figure 1, comprise frame, be arranged on the screw extruder (see accompanying drawing 2) of frame top, the spheronizator (see accompanying drawing 3) being arranged on frame front end and the blower fan 1 supporting with spheronizator be arranged on bottom frame, the discharging opening of described screw extruder is positioned at directly over spheronizator hopper 8, described screw extruder comprises the support 14 be vertically fixedly mounted on above frame, extruder motor 17, reductor 16, extrusion screw rod 11 and extruder hopper 13, described support 14 left surface installs extruded tube 12 by means of pressing plate level, suit extrusion screw rod 11 in extruded tube 12, the extruder hopper 13 with extruded tube 12 inner space is installed on extruded tube 12 outer wall top, extruded tube 12 end outer wall also arranges coolant jacket 19, described extruded tube 12 open end is installed by means of gland nut 9 and is extruded orifice plate 10, one end that described extrusion screw rod 11 is positioned at pressing plate is arranged through the through hole in the middle part of support 14, support 14 right flank fixedly mounts bearing outside 20, be positioned at the extrusion screw rod 11 of bearing outside 20 by Morse's cone anatomical connectivity bearing inner sleeve 21, between bearing inner sleeve 21 and bearing outside 20, bearing is installed, described bearing inner sleeve connects reductor 16 by means of the first shaft coupling 3, reductor 16 power intake is connected with extruder motor 17 clutch end, describedly extrude uniform isodiametric through hole on orifice plate 10, percent opening is 30%, and the ratio extruding orifice plate 10 thickness and through-hole diameter is 3-5:1, described spheronizator comprises the vertical round as a ball cylinder 7 arranged, be arranged on the frictional disk 5 in round as a ball cylinder 7, the spheronizator hopper 8 be arranged on round as a ball cover 26 is vertically arranged on the overcoat in the middle part of round as a ball cylinder 7 base plate, vertically be arranged on the main shaft 30 in the middle part of frictional disk 5, the inner sleeve 29 be connected with main shaft 30 lower end and the round as a ball motor 2 be connected with inner sleeve 29 lower end by means of the second shaft coupling 15, described frictional disk 5 is medial recess, and the disk-like structure that edge is upwards dug, its outer rim and round as a ball cylinder 7 inwall matched in clearance, described frictional disk 5 is positioned in the middle part of round as a ball cylinder 7, described outer set upper side is fixedly connected with round as a ball tube end plate, bearing is fixedly mounted between described inner sleeve 29 and overcoat, the fixed installation of described overcoat top and bottom is used for the bearing (ball) cover 28 of pressing bearing, Morse's cone anatomical connectivity is adopted between described main shaft 30 lower end and inner sleeve 29, described round as a ball tube end plate is also vertically provided with the ajutage 31 with its inner space, described ajutage 31 lower end is communicated with blower fan 1 air outlet.
In concrete use procedure, first the material mixed is dropped into extruder hopper 13, material enters extruded tube 12 by extruder hopper 13, under the effect of extrusion screw rod 11, material is pushed to and extrude orifice plate, extruding orifice plate 10 makes material become strip structure, the material of strip structure falls in spheronizator hopper 8, and enter round as a ball cylinder, the material entering round as a ball cylinder clashes under the effect of the centrifugal force of frictional disk on the inwall of round as a ball cylinder, form the short cylindrical shape structure of fracture, short cylindrical shape structure forms micropill through constantly clashing into, and compare existing vibration granulating mode, the micropill diameter that can be formed can at below 1mm, improve production automation degree, this utility model is by medicine material, list structure is extruded into after excipient and binder combination are mixed by screw extruder, the list structure extruded falls in round as a ball cylinder, under the effect of frictional disk, list structure with roll cylinder inner wall and clash into the section of fragmenting into, and ball-type micropill is formed gradually under the effect of frictional disk, the diameter of microspheric granula can regulate by controlling frictional disk rotating speed, be applicable to the processing of below 1mm ball-type micropill.

Claims (3)

1. a machine for making small ball type granulating materials, it is characterized in that: comprise frame, be arranged on the screw extruder of frame top, the spheronizator being arranged on frame front end and the blower fan (1) supporting with spheronizator be arranged on bottom frame, the discharging opening of described screw extruder is positioned at directly over spheronizator hopper (8), described screw extruder comprises the support (14) be vertically fixedly mounted on above frame, extruder motor (17), reductor (16), extrusion screw rod (11) and extruder hopper (13), described support (14) left surface installs extruded tube (12) by means of pressing plate level, suit extrusion screw rod (11) in extruded tube (12), the extruder hopper (13) with extruded tube (12) inner space is installed on extruded tube (12) outer wall top, extruded tube (12) end outer wall also arranges coolant jacket (19), described extruded tube (12) open end is installed by means of gland nut (9) and is extruded orifice plate (10), described extrusion screw rod (11) is positioned at the through hole setting of one end through support (14) middle part of pressing plate, support (14) right flank fixedly mounts bearing outside (20), be positioned at the extrusion screw rod (11) of bearing outside (20) by Morse's cone anatomical connectivity bearing inner sleeve (21), between bearing inner sleeve (21) and bearing outside (20), bearing is installed, described bearing inner sleeve connects reductor (16) by means of the first shaft coupling (3), reductor (16) power intake is connected with extruder motor (17) clutch end.
2. machine for making small ball type granulating materials according to claim 1, is characterized in that: described in extrude the upper uniform isodiametric through hole of orifice plate (10), percent opening is 30%, and the ratio extruding orifice plate (10) thickness and through-hole diameter is 3-5:1.
3. machine for making small ball type granulating materials according to claim 2, it is characterized in that: described spheronizator comprises the vertical round as a ball cylinder (7) arranged, be arranged on the frictional disk (5) in round as a ball cylinder (7), the spheronizator hopper (8) be arranged on round as a ball cover (26) is vertically arranged on the overcoat in the middle part of round as a ball cylinder (7) base plate, vertically be arranged on the main shaft (30) at frictional disk (5) middle part, the inner sleeve (29) be connected with main shaft (30) lower end and the round as a ball motor (2) be connected with inner sleeve (29) lower end by means of the second shaft coupling (15), described frictional disk (5) is medial recess, and the disk-like structure that edge is upwards dug, its outer rim and round as a ball cylinder (7) inwall matched in clearance, described frictional disk (5) is positioned at round as a ball cylinder (7) middle part, described outer set upper side is fixedly connected with round as a ball tube end plate, bearing is fixedly mounted between described inner sleeve (29) and overcoat, the fixed installation of described overcoat top and bottom is used for the bearing (ball) cover (28) of pressing bearing, Morse's cone anatomical connectivity is adopted between described main shaft (30) lower end and inner sleeve (29), described round as a ball tube end plate is also vertically provided with and the ajutage of its inner space (31), described ajutage (31) lower end is communicated with blower fan (1) air outlet.
CN201520023591.4U 2015-01-14 2015-01-14 Machine for making small ball type granulating materials Expired - Fee Related CN204395003U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201520023591.4U CN204395003U (en) 2015-01-14 2015-01-14 Machine for making small ball type granulating materials

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201520023591.4U CN204395003U (en) 2015-01-14 2015-01-14 Machine for making small ball type granulating materials

Publications (1)

Publication Number Publication Date
CN204395003U true CN204395003U (en) 2015-06-17

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ID=53418912

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201520023591.4U Expired - Fee Related CN204395003U (en) 2015-01-14 2015-01-14 Machine for making small ball type granulating materials

Country Status (1)

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CN (1) CN204395003U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108380137A (en) * 2018-03-07 2018-08-10 霍尔果斯汉智医药科技有限公司 A kind of multi-functional pellet granulator
CN109719633A (en) * 2019-01-25 2019-05-07 广州金谷钻石工具有限公司 A kind of pore forming particles and production method of cutter head

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108380137A (en) * 2018-03-07 2018-08-10 霍尔果斯汉智医药科技有限公司 A kind of multi-functional pellet granulator
CN108380137B (en) * 2018-03-07 2023-10-20 霍尔果斯汉智医药科技有限公司 Multifunctional pellet granulator
CN109719633A (en) * 2019-01-25 2019-05-07 广州金谷钻石工具有限公司 A kind of pore forming particles and production method of cutter head
CN109719633B (en) * 2019-01-25 2021-11-16 广州金谷钻石工具有限公司 Pore-forming particles of tool bit and manufacturing method

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150617

Termination date: 20200114

CF01 Termination of patent right due to non-payment of annual fee