CN204192794U - Rodent respiratory system exposes contamination device - Google Patents

Rodent respiratory system exposes contamination device Download PDF

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Publication number
CN204192794U
CN204192794U CN201420670323.7U CN201420670323U CN204192794U CN 204192794 U CN204192794 U CN 204192794U CN 201420670323 U CN201420670323 U CN 201420670323U CN 204192794 U CN204192794 U CN 204192794U
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CN
China
Prior art keywords
port
respiratory system
flue tube
flue
port structure
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Expired - Fee Related
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CN201420670323.7U
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Chinese (zh)
Inventor
王伟明
张俊威
王博
齐绪交
肖洋
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HEILONGJIANG ACADEMY OF TCM
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HEILONGJIANG ACADEMY OF TCM
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Priority to CN201420670323.7U priority Critical patent/CN204192794U/en
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Publication of CN204192794U publication Critical patent/CN204192794U/en
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Abstract

Rodent respiratory system exposes contamination device, belongs to a kind of contamination device.This utility model is complicated in order to solve existing smoke exposure apparatus structure, and volume is large, and smoke collection part and sootiness part are integrated, and easily cause the problem that laboratory animal is scalded.Rodent respiratory system described in the utility model exposes contamination device, comprise smoke collection case, flue tube and fumigation case, smoke collection case is connected by flue tube with fumigation case, reduces the heat produced in cigarette combustion smog, makes the temperature constant in fumigation case.This utility model volume is little, and capacity is large, can test modeling to great many of experiments animal simultaneously, reduces group difference and other environmental disturbances.And ensure the gregarious habit of laboratory animal, environment orthobiosis of simulated animal, not constraint, make animal be in freely movable state, thus acquisition tests receptor more accurately.

Description

Rodent respiratory system exposes contamination device
Technical field
This utility model belongs to a kind of contamination device, particularly relates to a kind of animal breath system and exposes formula contamination device.
Background technology
The experiment of laboratory animal gas exposure is the basic skills of gas toxicity assessment; laboratory animal gas exposure device is the important stage property in this experiment; can be used for simulating the toxic condition through inhalation exposure, be widely used in environmental conservation, industrial hygiene, drug research and toxicity Journal of Sex Research.But existing smoke exposure apparatus structure is complicated, volume is large, and smoke collection part and sootiness part are integrated, and easily cause experiments experiment animal to scald, non-uniform temperature, environment disunity, experiment receptor is caused to produce difference.
Utility model content
This utility model is complicated in order to solve existing smoke exposure apparatus structure, and volume is large, and smoke collection part and sootiness part are integrated, and easily cause the problem that laboratory animal is scalded, and now provides rodent respiratory system to expose contamination device.
Rodent respiratory system exposes contamination device, and it comprises: smoke collection case, flue tube and fumigation case; The outlet flue of smoke collection case is connected with the mouth that enters of fumigation case by flue tube.
Above-mentioned flue tube is provided with n turning, and n is the positive integer be more than or equal to.
The mouth place of entering of above-mentioned fumigation case is provided with separation net.
Above-mentioned rodent respiratory system exposes contamination device and also comprises: loose cigarette plate; Loose cigarette plate has m smoke-dispelling hole, and wherein m is positive integer; Loose cigarette plate is fixed on fumigation case interior lower end.
Above-mentioned rodent respiratory system exposes contamination device and also comprises: rotating disk, protection network and motor; Rotating disk is hollow structure, and surface is provided with aperture, and the outlet flue of flue tube is connected with the axle center place of rotating disk, and for being rotationally connected between flue tube and rotating disk, motor is for driving dial rotation, and protection network is fixed on above rotating disk.
The top of fumigation case or the top of sidewall are provided with exhaust outlet.
Above-mentioned rodent respiratory system exposes contamination device and also comprises: exhaust fan, exhaust fan is fixed on exhaust outlet place above fumigation case, and motor rotates for driving exhaust fan.
Rodent respiratory system exposes contamination device, and it comprises: flue tube, fumigation case, two unidirectional baffle plates, three-port structure, piston and cigarette holders;
The mouth that enters of fumigation case is connected with the outlet flue of flue tube;
The port of piston is communicated with first of three-port structure port, and the second port of this three-port structure is connected with the outlet flue of cigarette holder, and the 3rd port of this three-port structure is connected with the mouth that enters of flue tube;
Between described three-port structure and the outlet flue of cigarette holder, be provided with an individual event baffle plate, this unidirectional baffle plate only can be opened towards three-port structure side,
Described three-port structure and entering between mouth of flue tube are provided with a unidirectional baffle plate, and this unidirectional baffle plate only can be opened to flue tube side,
Piston can move reciprocatingly in first of a three-port structure port.
Rodent respiratory system exposes contamination device, and it is characterized in that, it comprises: flue tube, fumigation case, two check valves, three-port structure, piston and cigarette holders;
The mouth that enters of fumigation case is connected with the outlet flue of flue tube;
The port of piston is communicated with first of three-port structure port, and the second port of this three-port structure is connected with the outlet flue of cigarette holder, and the 3rd port of this three-port structure is connected with the mouth that enters of flue tube;
Between described three-port structure and the outlet flue of cigarette holder, be provided with an individual event valve, this check valve only can be opened towards three-port structure side,
Described three-port structure and entering between mouth of flue tube are provided with a check valve, and this check valve only can be opened to flue tube side,
Piston can move reciprocatingly in first of a three-port structure port.
Rodent respiratory system described in the utility model exposes contamination device, comprise smoke collection case, flue tube and fumigation case, smoke collection case is connected by flue tube with fumigation case, reduces the heat produced in cigarette combustion smog, makes the temperature constant in fumigation case.
This utility model controls the suction of smog by piston, and simulation human body smoking process, can make medicated cigarette burn incompletely, produce the composition identical with mankind's smoking, at utmost close to human disease's environment.By controlling motor, smog being discharged at regular time and quantity, making smokescope controlled.Ensure that in fumigation case, smokescope is constant by exhaust fan, ensure oxygen turnover simultaneously.By rotating disk and loose cigarette plate, smog is evenly spread in whole fumigation case, ensures to be full of in fumigation case to continue and the smog of equilibrium concentration, make smog be dispersed in each portion of casing, reach environment unified, difference in minimizing group.
This utility model volume is little, and capacity is large, can test modeling to great many of experiments animal simultaneously, reduces group difference and other environmental disturbances.And ensure the gregarious habit of laboratory animal, environment orthobiosis of simulated animal, not constraint, make animal be in freely movable state, thus acquisition tests receptor more accurately.This utility model, by the long-time stimulation test animal of smog, causes laboratory animal respiratory system disease, is mainly used in laboratory animal chronic bronchitis model or coordinates other experiment materials to cause COPD (chronic obstructive pulmonary disease) animal model.
Accompanying drawing explanation
Fig. 1 is the sectional view of the rodent respiratory system exposure contamination device described in detailed description of the invention one;
Fig. 2 is the electrical structure schematic diagram of the rodent respiratory system exposure contamination device described in detailed description of the invention one;
Fig. 3 is the sectional view of the rodent respiratory system exposure contamination device described in detailed description of the invention ten;
Fig. 4 is the electrical structure schematic diagram of the rodent respiratory system exposure contamination device described in detailed description of the invention ten.
Detailed description of the invention
Detailed description of the invention one: see figures.1.and.2 and illustrate present embodiment, the rodent respiratory system described in present embodiment exposes contamination device, and it comprises: smoke collection case 2, flue tube 3 and fumigation case 6;
The outlet flue of smoke collection case 2 is connected with the mouth that enters of fumigation case 6 by flue tube 3.
Contamination device described in present embodiment is divided into three parts, by flue tube 3, smoke collection case 2 is connected with fumigation case 6, when practical application, medicated cigarette 1 being lighted is positioned in smoke collection case 2, smog flows to fumigation case 6 after being transmitted by flue tube 3, heat distributes in the transmitting procedure of flue tube 3 by smog, the temperature of smog can be effectively reduced, thus prevent animal for research in fumigation case 6 to be burned, also can ensure the constant of temperature in fumigation case 6, prevent from affecting test effect because fumigation case 6 internal temperature is too high.Meanwhile, for the ease of placing laboratory animal, the sidewall of fumigation case 6 is also provided with sliding door.
Detailed description of the invention two: present embodiment be to described in detailed description of the invention one rodent respiratory system expose contamination device be described further, in present embodiment, described flue tube 3 is provided with n turning, n be more than or equal to 3 positive integer.
Smog transmits in the flue tube 3 being provided with n turning, can allow smog abundant distribute heat in flue tube 3, ensures that the smog temperature entered in fumigation case 6 is identical with room temperature.
Detailed description of the invention three: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention one to be described further, and in present embodiment, the mouth place of entering of described fumigation case 6 is provided with separation net.
Described separation net can prevent the Excreta of laboratory animal from falling in flue tube 3, prevents from blocking flue tube 3, and ensures that smog quality is not contaminated.
Detailed description of the invention four: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention one to be described further, and in present embodiment, it also comprises: loose cigarette plate 14;
Loose cigarette plate 14 has m smoke-dispelling hole, and wherein m is positive integer;
Loose cigarette plate 14 is fixed on fumigation case 6 interior lower end.
Add loose cigarette plate 14 in present embodiment, when practical application, loose cigarette plate 14 can hold bedding and padding, be conducive to the Excreta of clean laboratory animal.M smoke-dispelling hole on loose cigarette plate 14 can ensure that smog fully enters fumigation case.Meanwhile, m smoke-dispelling hole is convex type hole, is highly 3cm, can prevent the bedding and padding that loose cigarette plate 14 holds from spilling from smoke-dispelling hole like this.
Detailed description of the invention five: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention one, two, three or four to be described further, and in present embodiment, it also comprises: rotating disk 4, protection network 5 and motor 8;
Rotating disk 4 is hollow structure, and surface is provided with aperture, and the outlet flue of flue tube 3 is connected with the axle center place of rotating disk 4, and for being rotationally connected between flue tube 3 and rotating disk 4, motor 8 rotates for driving rotating disk 4,
Protection network 5 is fixed on above rotating disk 4.
In contamination device described in present embodiment, add rotating disk 4, protection network 5 and motor 8, motor 8 is adopted to drive rotating disk 4 to slowly run, in present embodiment, rotating disk is designed to hollow structure, is directly connected with the outlet flue of flue tube 3, along with the rotation of rotating disk, smog is disseminated in fumigation case 6 from the aperture of rotating disk, the smog in fumigation case 6 is evenly spread.Protection network 5 is positioned at above rotating disk 4, for supporting little laboratory animal, little laboratory animal and rotating disk 4 is isolated simultaneously, prevents rotating disk 4 from rotating and accidentally injures little laboratory animal, also prevents little laboratory animal from destroying rotating disk 4.Meanwhile, rotating disk 4 outer surface is provided with spiral lamination, can ensure that smog fully spreads.
Detailed description of the invention six: present embodiment exposes contamination device to the laboratory rodent respiratory system described in detailed description of the invention five to be described further, and in present embodiment, the rotating speed of rotating disk 4 is 20rad/min to 30rad/min.
Detailed description of the invention seven: present embodiment exposes contamination device to the laboratory rodent respiratory system described in detailed description of the invention five to be described further, and in present embodiment, the top of fumigation case 6 or the top of sidewall are provided with exhaust outlet.
When practical application, exhaust outlet place is provided with protection network, prevents little laboratory animal from climbing out of, or prevents laboratory animal from climbing to exhaust fan, causes little laboratory animal to sustain damage.
Detailed description of the invention eight: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention seven to be described further, in present embodiment, it also comprises: exhaust fan 7, exhaust fan 7 is fixed on exhaust outlet place above fumigation case 6, and motor 8 rotates for driving exhaust fan 7.
Add exhaust fan 7 in present embodiment, exhaust fan 7 can make fumigation case 6 inside keep ventilating with outside, thus ensures that in fumigation case 6, smokescope is even, oxygen content in guarantee fumigation case 6.
Detailed description of the invention nine: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention eight to be described further, in present embodiment, exhaust fan 7 is bi-directional discharging fan.
Detailed description of the invention ten: illustrate present embodiment with reference to Fig. 3 and Fig. 4, rodent respiratory system described in present embodiment exposes contamination device, and it comprises: flue tube 3, fumigation case 6, two unidirectional baffle plates 9, three-port structure 10, piston 11 and cigarette holders 13;
The mouth that enters of fumigation case 6 is connected with the outlet flue of flue tube 3;
The port of piston 11 is communicated with first port of three-port structure 10, and the second port of this three-port structure is connected with the outlet flue of cigarette holder 13, and the 3rd port of this three-port structure is connected with the mouth that enters of flue tube 3;
Between described three-port structure 10 and the outlet flue of cigarette holder 13, be provided with an individual event baffle plate, this unidirectional baffle plate only can be opened towards three-port structure 10 side,
Described three-port structure 10 and entering between mouth of flue tube 3 are provided with a unidirectional baffle plate, and this unidirectional baffle plate only can be opened to flue tube 3 side,
Piston 11 can move reciprocatingly in first of three-port structure 10 port.
Present embodiment is when reality uses, the smoke absorbing end of medicated cigarette is inserted on cigarette holder 13, can manually pull piston 11 reciprocating, also motor 8 drive transmission device 12 can be utilized to drive piston 11 to slide in smoke collection case 2, when drive mechanism 12 pulls piston 11, a unidirectional slide 9 is opened, and No. two unidirectional slides 10 are closed, cigarette holder 13 is by smog inspiration, and smog is drawn in smoke collection case 2; When drive mechanism 12 promotes piston 11, a unidirectional slide 9 is closed, and No. two unidirectional slides 10 are opened, and the smog in smoke collection case 2 is pushed in flue tube 3, thus enters fumigation case 6.The form that the motor 8 adopted in present embodiment is combined by large and small gear, carrys out control piston speed, makes the speed uniform, controllable of suction or vapour discharge, ensures the smokescope that experiment is required constant.Drive mechanism 12 can convert the rotary motion that motor exports to rectilinear motion, thus drives piston movement.
Detailed description of the invention 11: illustrate present embodiment with reference to Fig. 3 and Fig. 4, rodent respiratory system described in present embodiment exposes contamination device, and it comprises: flue tube 3, fumigation case 6, two check valves, three-port structure 10, piston 11 and cigarette holders 13;
The mouth that enters of fumigation case 6 is connected with the outlet flue of flue tube 3;
The port of piston 11 is communicated with first port of three-port structure 10, and the second port of this three-port structure is connected with the outlet flue of cigarette holder 13, and the 3rd port of this three-port structure is connected with the mouth that enters of flue tube 3;
Between described three-port structure 10 and the outlet flue of cigarette holder 13, be provided with an individual event valve, this check valve only can be opened towards three-port structure 10 side,
Described three-port structure 10 and entering between mouth of flue tube 3 are provided with a check valve, and this check valve only can be opened to flue tube 3 side,
Piston 11 can move reciprocatingly in first of three-port structure 10 port.
Detailed description of the invention ten and the rodent respiratory system described in 11 expose contamination device, by motor and piston simulation human body respiration process, obtain the medicated cigarette environment in people's suction body, solve existing contamination device and be merely able to simulation second hand smoking environment, thus cause existing exposure experiment to obtain the large problem of resultant error.
Detailed description of the invention 12: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention ten or 11 to be described further, and in present embodiment, cigarette holder 13 is bull cigarette holder.
Described bull cigarette holder can simultaneously grafting many medicated cigarettes, reach the effect simultaneously gathering a large amount of smog, are applicable to contaminate to multiple receptor simultaneously, prevent difference.
Detailed description of the invention 13: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention 12 to be described further, and in present embodiment, it also comprises: plug, and this plug is used for the cigarette holder mouth of free time to seal.
Plug can fill bull cigarette holder in experimentation with less than hole, the seal of assurance device, also ensures to suck the concentration of smog.
Detailed description of the invention 14: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention ten or 11 to be described further, and in present embodiment, it also comprises: disposable box, and this disposable box is positioned at below cigarette holder 13.
Disposable box, for collecting the cigarette end after burning and flue dust, prevents flue dust to be scattered everywhere, damages indoor environment.
Detailed description of the invention 15: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention one, ten or 11 to be described further, and in present embodiment, the material of fumigation case 6 is lucite.
The material of the smoke collection case 2 described in detailed description of the invention one is also lucite.
Detailed description of the invention 16: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention one, ten or 11 to be described further, in present embodiment, described smoke collection case 2, between flue tube 3 and fumigation case 6 for removably connecting.
Detailed description of the invention 17: present embodiment exposes contamination device to the rodent respiratory system described in detailed description of the invention ten or 11 to be described further, in present embodiment, described cigarette holder 13, three-port structure 10, be between flue tube 3 and fumigation case 6 and removably connect.
Described in detailed description of the invention 16 and 17, contamination device is for removably connecting, and is convenient to cleaning, can guard box environment.

Claims (10)

1. rodent respiratory system exposes contamination device, and it is characterized in that, it comprises: smoke collection case (2), flue tube (3) and fumigation case (6);
The outlet flue of smoke collection case (2) is connected with the mouth that enters of fumigation case (6) by flue tube (3).
2. rodent respiratory system according to claim 1 exposes contamination device, and it is characterized in that, described flue tube (3) is provided with n turning, n be more than or equal to 3 positive integer.
3. rodent respiratory system according to claim 1 exposes contamination device, and it is characterized in that, the mouth place of entering of described fumigation case (6) is provided with separation net.
4. rodent respiratory system according to claim 1 exposes contamination device, and it is characterized in that, it also comprises: loose cigarette plate (14);
Loose cigarette plate (14) has m smoke-dispelling hole, and wherein m is positive integer;
Loose cigarette plate (14) is fixed on fumigation case (6) interior lower end.
5. the rodent respiratory system according to claim 1,2,3 or 4 exposes contamination device, and it is characterized in that, it also comprises: rotating disk (4), protection network (5) and motor (8);
Rotating disk (4) is hollow structure, and surface is provided with aperture, the outlet flue of flue tube (3) is connected with the axle center place of rotating disk (4), and for being rotationally connected between flue tube (3) and rotating disk (4), motor (8) rotates for driving rotating disk (4)
Protection network (5) is fixed on rotating disk (4) top.
6. rodent respiratory system according to claim 5 exposes contamination device, and it is characterized in that, the top of fumigation case (6) or the top of sidewall are provided with exhaust outlet.
7. rodent respiratory system according to claim 6 exposes contamination device, it is characterized in that, it also comprises: exhaust fan (7), exhaust fan (7) is fixed on exhaust outlet place, fumigation case (6) top, and motor (8) rotates for driving exhaust fan (7).
8. rodent respiratory system exposes contamination device, it is characterized in that, it comprises: flue tube (3), fumigation case (6), two unidirectional baffle plates (9), three-port structure (10), piston (11) and cigarette holders (13);
The mouth that enters of fumigation case (6) is connected with the outlet flue of flue tube (3);
The port of piston (11) is communicated with first port of three-port structure (10), second port of this three-port structure is connected with the outlet flue of cigarette holder (13), and the 3rd port of this three-port structure is connected with the mouth that enters of flue tube (3);
Between described three-port structure (10) and the outlet flue of cigarette holder (13), be provided with an individual event baffle plate, this unidirectional baffle plate only can be opened towards three-port structure (10) side,
Described three-port structure (10) and entering between mouth of flue tube (3) are provided with a unidirectional baffle plate, and this unidirectional baffle plate only can be opened to flue tube (3) side,
Piston (11) can move reciprocatingly in first port of three-port structure (10).
9. rodent respiratory system exposes contamination device, it is characterized in that, it comprises: flue tube (3), fumigation case (6), two check valves, three-port structure (10), piston (11) and cigarette holders (13);
The mouth that enters of fumigation case (6) is connected with the outlet flue of flue tube (3);
The port of piston (11) is communicated with first port of three-port structure (10), second port of this three-port structure is connected with the outlet flue of cigarette holder (13), and the 3rd port of this three-port structure is connected with the mouth that enters of flue tube (3);
Between described three-port structure (10) and the outlet flue of cigarette holder (13), be provided with an individual event valve, this check valve only can be opened towards three-port structure (10) side,
Described three-port structure (10) and entering between mouth of flue tube (3) are provided with a check valve, and this check valve only can be opened to flue tube (3) side,
Piston (11) can move reciprocatingly in first port of three-port structure (10).
10. the rodent respiratory system according to claim 1,8 or 9 exposes contamination device, it is characterized in that, is and removably connects between all parts of described device.
CN201420670323.7U 2014-11-11 2014-11-11 Rodent respiratory system exposes contamination device Expired - Fee Related CN204192794U (en)

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Application Number Priority Date Filing Date Title
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104720927A (en) * 2015-04-14 2015-06-24 南华大学 Oil-smoke movable toxicant exposure device
CN105242008A (en) * 2015-09-23 2016-01-13 同济大学 Toxicant exposure testing apparatus used for regulating and controlling volatile organic compound gaseous-state pollution concentration
CN107280804A (en) * 2016-04-13 2017-10-24 北京元和基因科技有限公司 It is a kind of to study the experimental rig that smoking influence on angiocardiopathy generation
CN108240914A (en) * 2016-12-23 2018-07-03 中国医学科学院药物研究所 Toy flue gas sucks microenvironment preparation system
CN109557254A (en) * 2018-11-14 2019-04-02 云南中烟工业有限责任公司 A method of establishing standardization cigarette smoke mouse mouth and nose process for exposing
CN110711048A (en) * 2019-10-15 2020-01-21 上海塔望智能科技有限公司 Animal smoking and toxicant exposure device

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104720927A (en) * 2015-04-14 2015-06-24 南华大学 Oil-smoke movable toxicant exposure device
CN105242008A (en) * 2015-09-23 2016-01-13 同济大学 Toxicant exposure testing apparatus used for regulating and controlling volatile organic compound gaseous-state pollution concentration
CN105242008B (en) * 2015-09-23 2017-07-11 同济大学 It is a kind of to be used to regulate and control the contamination experimental apparatus of volatile organic matter gaseous contamination concentration
CN107280804A (en) * 2016-04-13 2017-10-24 北京元和基因科技有限公司 It is a kind of to study the experimental rig that smoking influence on angiocardiopathy generation
CN108240914A (en) * 2016-12-23 2018-07-03 中国医学科学院药物研究所 Toy flue gas sucks microenvironment preparation system
CN109557254A (en) * 2018-11-14 2019-04-02 云南中烟工业有限责任公司 A method of establishing standardization cigarette smoke mouse mouth and nose process for exposing
CN109557254B (en) * 2018-11-14 2021-08-03 云南中烟工业有限责任公司 Method for establishing standardized cigarette smoke mouse mouth and nose exposure method
CN110711048A (en) * 2019-10-15 2020-01-21 上海塔望智能科技有限公司 Animal smoking and toxicant exposure device

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Granted publication date: 20150311

Termination date: 20171111