CN109820617A - One kind is for passive smoking or ozone contamination COPD modeling device - Google Patents
One kind is for passive smoking or ozone contamination COPD modeling device Download PDFInfo
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- CN109820617A CN109820617A CN201910234760.1A CN201910234760A CN109820617A CN 109820617 A CN109820617 A CN 109820617A CN 201910234760 A CN201910234760 A CN 201910234760A CN 109820617 A CN109820617 A CN 109820617A
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- cabinet
- air
- connection tube
- upper cover
- copd
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- 238000011109 contamination Methods 0.000 title claims abstract description 23
- 230000000391 smoking effect Effects 0.000 title claims abstract description 17
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 title claims abstract description 14
- 235000019504 cigarettes Nutrition 0.000 claims abstract description 23
- 238000007664 blowing Methods 0.000 claims abstract description 14
- 230000006698 induction Effects 0.000 claims abstract description 14
- 230000001105 regulatory effect Effects 0.000 claims description 5
- 239000005341 toughened glass Substances 0.000 claims description 4
- 239000011521 glass Substances 0.000 claims description 3
- 238000004026 adhesive bonding Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000007789 gas Substances 0.000 description 19
- 238000012360 testing method Methods 0.000 description 13
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 9
- 238000000034 method Methods 0.000 description 4
- 238000010171 animal model Methods 0.000 description 3
- 235000019506 cigar Nutrition 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000003292 glue Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000000779 smoke Substances 0.000 description 2
- 231100000167 toxic agent Toxicity 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- 244000061176 Nicotiana tabacum Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000002485 combustion reaction Methods 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 230000036228 toxication Effects 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
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- Ventilation (AREA)
Abstract
One kind is for passive smoking or ozone contamination COPD modeling device, including cabinet, the first upper cover and the second upper cover are provided on the cabinet, bottom gas outlet is provided on the cabinet, multilayer diffuser plate is provided in the cabinet, cigarette mouth is provided on the cabinet, air blowing assembly is provided in the cigarette mouth, the lower end of the cigarette mouth is provided with the first connection tube, air induction hose is communicated on first connection tube, the air induction hose is connect with bottom gas outlet, one end of first connection tube is communicated with the second connection tube, air-breathing assembly is provided on second connection tube.This is used for passive smoking or ozone contamination COPD modeling device, apparatus of the present invention for contamination gas by several admission lines from outside by being actively blown into or passively suck in box house separate space, when using suction, admission line can connect different contamination sources.
Description
Technical field
It is specially a kind of to be filled for passive smoking or ozone contamination COPD modeling the present invention relates to COPD modeling technical field
It sets.
Background technique
Experimental animal (rat, mouse) is mainly placed in Environmental Tobacco Smoke in Non-industrial Area of China by passive smoking flue toxicity contaminated model, simulates people
Class passive smoking process, establishes Chronic obstructive pulmonary disease, in order to clearly know flue toxicity contaminated and respiratory system disease
Relationship between disease.
Animal contaminated model equipment in the prior art be usually in closed experimental box, or by an experimental box with every
Several parts are separated into from plate, environment locating for experimental animal is just the same, it has not been convenient to carry out parallel under different pharmacology states
Experiment, the cigarette there are also current toxicant exposure box is mainly that oblique cutting is fixed in cabinet on the side wall of toxicant exposure box, or with bracket,
The bad control of the burning velocity of cigarette, smokescope is not first-class, and operation is also inconvenient.
Summary of the invention
The purpose of the present invention is to provide one kind for passive smoking or ozone contamination COPD modeling device, to solve tradition
Mode can not carry out the problem of parallel laboratory test under different pharmacology.
To achieve the above object, the invention provides the following technical scheme: a kind of be used for passive smoking or ozone contamination COPD
Modeling device, including cabinet are provided with the first upper cover and the second upper cover on the cabinet, bottom outlet are provided on the cabinet
Mouthful, it is provided with multilayer diffuser plate in the cabinet, cigarette mouth is provided on the cabinet, it is total that air blowing is provided in the cigarette mouth
At the lower end of the cigarette mouth is provided with the first connection tube, and air induction hose is communicated on first connection tube, and the air inlet is soft
Pipe is connect with bottom gas outlet, and one end of first connection tube is communicated with the second connection tube, is arranged on second connection tube
There is air-breathing assembly, air-out hose is provided on second connection tube, the air-out hose passes through the second upper cover and is inserted into cabinet
It is interior.
Preferably, the cabinet is made of transparent toughened glass.
Preferably, second upper cover and cabinet are cut with scissors by glass glue sticking, the first upper cover and the second upper cover by hinge
Fixation is connect, the first upper cover is opened and closed by this hinge.
Preferably, the bottom gas outlet is single-open tubular structure, and open end is fixedly connected with air induction hose, bottom
Several holes are provided on gas outlet.
Preferably, the air blowing assembly and air-breathing assembly are by a mini fan and a miniature regulating flow quantity valve
Composition.
Compared with prior art, the beneficial effects of the present invention are: this is used for passive smoking or ozone contamination COPD modeling dress
Set: 1, apparatus of the present invention for contamination gas by several admission lines from outside by be actively blown into or passive inlet box body in
In portion's separate space, when using suction, admission line can connect different contamination sources, when only a kind of contamination source into
It can also suck and be blown into mode when the multiple batches of test of row while carry out using being blown into mode, make the equipment can be in this way
The test for adapting to multiplicity needs, and cabinet is all made of transparent material, can observe life of the animal in case internal toxication at any time
Situation is deposited, since material uses tempered glass, performance is stablized, and will not cause using discoloration to vision because of temperature or for a long time
It influences；
2, there are several independent spaces inside the device of the invention, several different contamination source COPD modelings can be carried out simultaneously,
Facilitate contrastive test as a result, reducing the testing time, shortens test period, improved efficiency several times；
3, the device of the invention contamination source is placed in outside cabinet, and cigarette combustion smog passes through admission line after filter tip filters again
Into independent lab space, the smog that enters in test cell in this way and cigarette is placed in test cell directly lights generation
Smog ratio is closer to passive smoking under natural conditions, and experimental result is more acurrate, and reference value is higher；
4, smog flows out between top layer experimental animal from bottom air inlet and has several layers of porous barrier to be expanded in apparatus of the present invention
It dissipates, makes the smog for reaching top layer more uniform in this way, reduce individual because of the uneven testing differentia generated of sucking；
5, apparatus of the present invention intake line and blow pipe have flow rate adjustment device, can according to need and actual observation situation
It is any to adjust concentration.
Detailed description of the invention
Fig. 1 is overall structure front schematic view of the invention；
Fig. 2 is overall structure schematic rear view of the invention.
In figure: 1 cabinet, 2 first upper covers, 3 second upper covers, 4 bottom gas outlets, 5 multilayer diffuser plates, 6 cigarette mouths, 7 are blown
Assembly, 8 air induction hoses, 9 air-out hoses, 10 air-breathing assemblies, 11 first connection tubes, 12 second connection tubes.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Please refer to Fig. 1 and Fig. 2, the present invention provides a kind of technical solution: one kind is for passive smoking or ozone contamination COPD
Modeling device, including cabinet 1 are provided with the first upper cover 2 and the second upper cover 3 on cabinet 1, are provided with bottom gas outlet on cabinet 1
4, multilayer diffuser plate 5 is provided in cabinet 1, constantly spreads that reach upper layer more uniform to reach smog by several layers of diffuser plate
Purpose reduces each group of test object in test process and is arranged on cabinet 1 because sucking smog unevenly generates the otherness of test
There are cigarette mouth 6, cigarette mouth 6 and cabinet 1 by screw connection, the cigarette that more are lighted is inserted on following suction nozzle, cigarette mouth 6
On be provided with air blowing assembly 7, air blowing assembly 7 burning will generate ground smog extraction at cigarette mouth 6, and the lower end of cigarette mouth 6 is provided with
First connection tube 11, is communicated with air induction hose 8 on the first connection tube 11, the smog that air blowing assembly 7 is extracted out thus releasable hose
It is transported to bottom gas outlet 4, air induction hose 8 is connect with bottom gas outlet 4, it is provided with air-breathing assembly 10 on the second connection tube 12,
Outside the exhaust gas discharge cabinet 1 after experiment, air-out hose 9 is provided on the second connection tube 12, air-out hose 9 passes through on second
Lid 3 is inserted into cabinet 1.
Refering to fig. 1, cabinet 1 is made of the tempered glass of transparent material, and experimental status can be observed in real time, with partition point
At several independent spaces, to meet several test items while carry out.
Refering to fig. 1, the second upper cover 3 is cut with scissors by glass glue sticking, the first upper cover 2 and the second upper cover 3 by hinge with cabinet 1
Fixation is connect, the first upper cover is opened and closed by this hinge, is removed and placed into convenient for experimental subjects.
Refering to fig. 1 and Fig. 2, bottom gas outlet 4 are single-open tubular structure, and open end is fixedly connected with air induction hose 8,
Several holes are provided on bottom gas outlet 4, it is uniform convenient for smoke.
Referring to Fig.2, air blowing assembly 7 and air-breathing assembly 10 are by a mini fan and a miniature regulating flow quantity valve
Composition, conveying of the mini fan for gas are circulated, and air ventilation passage can be opened and closed in miniature regulating flow quantity valve,
And the control that size carries out gas flow is opened according to valve.
The present invention is in the specific implementation: can raise the first upper cover 2 with hand and open, experimental subjects is put into not as needed
In same 1 unitary space of cabinet on top layer's diffuser plate of multilayer diffuser plate 5, it then can raise the first upper cover 2 and shut, it will be fragrant
Cigarette is put on the suction nozzle of 6 bottom of cigar lighter, with lighter by cigarette lighter, opens mini fan and opening on air blowing assembly 7
Corresponding miniature regulating flow quantity valve, 6 midpoint of cigar lighter are burnt incense the suction that generates in air blowing assembly 7 of smog of cigarette generation
Under, it is flowed by the suction nozzle of cigaratte filter and cigar lighter 6 in the pipeline of air blowing assembly 7, then by the multiple of 7 downside of air blowing assembly
It is every to enter cabinet 1 by the air induction hose 8 being connected with these outlets and the bottom gas outlet 4 for being fixed on 1 bottom of cabinet for outlet
The bottom of a separate space, smog into space where multilayer diffuser plate 5 reaches top experimental subjects is crossed, then pass through on second again
Cabinet, because cabinet 1 is made of clear material, whole experiment process is discharged via air-breathing assembly 10 in the air-out hose 9 connected on lid 3
Electrodeless adjustment can be can according to need from external observation, air blowing assembly 7 and 10 flow of air-breathing assembly；Do the contamination of multiple gases
When testing while carrying out, the first upper cover 2 being raised with hand and is opened, it is single that experimental subjects is put into different cabinets 1 as needed
In first space on 5 top layer's diffuser plate of multilayer diffuser plate, it then can raise the first upper cover 2 and shut, by air induction hose 8 from air blowing
7 gas outlet of assembly disengages, and being connected to needs in contamination gas source to be tested, opens air-breathing assembly 10, what air-breathing assembly 10 generated
Suction is transmitted in each independent space of cabinet 1 by the air-out hose 9 between upper part air inlet and cabinet 1, gas of contaminating
Body is inhaled into each independent space of cabinet 1 by its air induction hose 8 and bottom gas outlet 4, and is flowed upward through more
Layer diffuser plate 5 reaches space where experimental subjects.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (5)
1. one kind is for passive smoking or ozone contamination COPD modeling device, including cabinet (1), it is characterised in that: the cabinet
(1) it is provided with the first upper cover (2) and the second upper cover (3) on, is provided with bottom gas outlet (4), the cabinet on the cabinet (1)
(1) it is provided with multilayer diffuser plate (5) in, is provided with cigarette mouth (6) on the cabinet (1), is provided with and blows on the cigarette mouth (6)
The lower end of gas assembly (7), the cigarette mouth (6) is provided with the first connection tube (11), is communicated on first connection tube (11)
Air induction hose (8), the air induction hose (8) connect with bottom gas outlet (4), and one end of first connection tube (11) is communicated with
Second connection tube (12) is provided with air-breathing assembly (10) on second connection tube (12), sets on second connection tube (12)
It is equipped with air-out hose (9), the air-out hose (9) passes through the second upper cover (3) and is inserted into cabinet (1).
2. one kind according to claim 1 is for passive smoking or ozone contamination COPD modeling device, it is characterised in that: institute
Cabinet (1) is stated to be made of transparent toughened glass.
3. one kind according to claim 1 is for passive smoking or ozone contamination COPD modeling device, it is characterised in that: institute
The second upper cover (3) and cabinet (1) are stated by glass gluing knot, the first upper cover (2) and the second upper cover (3) are hingedly solid by hinge
Fixed, the first upper cover (2) is opened and closed by this hinge.
4. one kind according to claim 1 is for passive smoking or ozone contamination COPD modeling device, it is characterised in that: institute
Stating bottom gas outlet (4) is single-open tubular structure, and open end is fixedly connected with air induction hose (8), on bottom gas outlet (4)
It is provided with several holes.
5. one kind according to claim 1 is for passive smoking or ozone contamination COPD modeling device, it is characterised in that: institute
Air blowing assembly (7) and air-breathing assembly (10) is stated to be made of a mini fan and a miniature regulating flow quantity valve.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910234760.1A CN109820617A (en) | 2019-03-26 | 2019-03-26 | One kind is for passive smoking or ozone contamination COPD modeling device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910234760.1A CN109820617A (en) | 2019-03-26 | 2019-03-26 | One kind is for passive smoking or ozone contamination COPD modeling device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109820617A true CN109820617A (en) | 2019-05-31 |
Family
ID=66872463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910234760.1A Pending CN109820617A (en) | 2019-03-26 | 2019-03-26 | One kind is for passive smoking or ozone contamination COPD modeling device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109820617A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110711048A (en) * | 2019-10-15 | 2020-01-21 | 上海塔望智能科技有限公司 | Animal smoking and toxicant exposure device |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101889908A (en) * | 2010-07-06 | 2010-11-24 | 首都医科大学附属北京朝阳医院 | Gas atomization toxicant exposure box |
| CN101897623A (en) * | 2010-08-04 | 2010-12-01 | 中国人民解放军第三军医大学 | Simulation smoke exposure experimental box |
| CN101912308A (en) * | 2010-08-04 | 2010-12-15 | 中国人民解放军第三军医大学 | Smoke exposure experimental device with condensing box |
| CN202342230U (en) * | 2011-12-13 | 2012-07-25 | 中国人民解放军第三军医大学第二附属医院 | Mouse atomization box |
| CN103340699A (en) * | 2013-07-05 | 2013-10-09 | 天津开发区合普工贸有限公司 | Mouth and nose type layered multi-concentration contamination control device |
| CN103385769A (en) * | 2013-08-19 | 2013-11-13 | 天津开发区合普工贸有限公司 | Integrated sectioning cavity multi-concentration gas contamination device |
| CN203436425U (en) * | 2013-08-19 | 2014-02-19 | 天津开发区合普工贸有限公司 | Integral split cavity multi-concentration gas infecting device |
| CN210138216U (en) * | 2019-03-26 | 2020-03-13 | 无锡市人民医院 | COPD (COPD) modeling device for passive smoking or ozone contamination |
-
2019
- 2019-03-26 CN CN201910234760.1A patent/CN109820617A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101889908A (en) * | 2010-07-06 | 2010-11-24 | 首都医科大学附属北京朝阳医院 | Gas atomization toxicant exposure box |
| CN101897623A (en) * | 2010-08-04 | 2010-12-01 | 中国人民解放军第三军医大学 | Simulation smoke exposure experimental box |
| CN101912308A (en) * | 2010-08-04 | 2010-12-15 | 中国人民解放军第三军医大学 | Smoke exposure experimental device with condensing box |
| CN202342230U (en) * | 2011-12-13 | 2012-07-25 | 中国人民解放军第三军医大学第二附属医院 | Mouse atomization box |
| CN103340699A (en) * | 2013-07-05 | 2013-10-09 | 天津开发区合普工贸有限公司 | Mouth and nose type layered multi-concentration contamination control device |
| CN103385769A (en) * | 2013-08-19 | 2013-11-13 | 天津开发区合普工贸有限公司 | Integrated sectioning cavity multi-concentration gas contamination device |
| CN203436425U (en) * | 2013-08-19 | 2014-02-19 | 天津开发区合普工贸有限公司 | Integral split cavity multi-concentration gas infecting device |
| CN210138216U (en) * | 2019-03-26 | 2020-03-13 | 无锡市人民医院 | COPD (COPD) modeling device for passive smoking or ozone contamination |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110711048A (en) * | 2019-10-15 | 2020-01-21 | 上海塔望智能科技有限公司 | Animal smoking and toxicant exposure device |
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