CN203842597U - Micro-fluidic chip with deformable membrane capable of preventing reflux - Google Patents
Micro-fluidic chip with deformable membrane capable of preventing reflux Download PDFInfo
- Publication number
- CN203842597U CN203842597U CN201420272519.0U CN201420272519U CN203842597U CN 203842597 U CN203842597 U CN 203842597U CN 201420272519 U CN201420272519 U CN 201420272519U CN 203842597 U CN203842597 U CN 203842597U
- Authority
- CN
- China
- Prior art keywords
- deformation
- liquid
- micro
- storage tank
- liquid storage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The utility model discloses a micro-fluidic chip with a deformable membrane capable of preventing reflux. The micro-fluidic chip comprises a semi-closed micro-fluidic chip and a deformable tectorial membrane, wherein a liquid pool, a reaction pool and a pore are formed in the semi-closed micro-fluidic chip; the liquid pool and the reaction pool are communicated through a fluid channel, and the reaction pool and the pore are communicated through a fluid channel; and the deformable tectorial membrane is arranged above the liquid pool; when the deformable tectorial membrane is deformed, a liquid in the liquid pool can be driven to flow inward the reaction tank. According to the chip, the feeding requirement and liquid retention can be kept without providing constant feeding pressure, and the acting force can be removed after single short acting force is provided to complete the operation, so that the amount of liquid entering the reaction pool can be controlled, and multi-stage liquid reactions can be sequentially performed according to requirements; the liquid cannot reflux after entering the reaction pool, and the operation method which needs constant acting force to guarantee continuous operation of the chip can be greatly optimized.
Description
Technical field
The utility model relate to a kind of have can deformation film anti-return micro-fluidic chip, belong to micro-fluidic chip technical field.
Background technology
Along with scientific and technical development, scientists just constantly makes great efforts that conventional Shi is tested to Zhuan Zhi ﹑ experimental technique and experimentation is microminiaturized.It is easy of integration that micro-fluidic chip has Di Xiao Hao ﹑ Gao Tong Liang ﹑, as improving chemistry and the Su Du ﹑ efficiency of bioanalysis and make the technology that analytical equipment reduces dimensionally and receive much concern, applies to widely the fields such as Sheng Wu ﹑ Yi ﹑ is chemical.Micro-fluidic chip is by the chips such as Bo Li ﹑ Shi Ying ﹑ Gui ﹑ plastics, microchannel or small reaction member being set, and detector, sample is carried out to Wei Liang ﹑ and analyze fast.But the sample in all micro-fluidic chips and reagent, all need certain driving force, make can move just and can complete detection in its microchannel in chip.Therefore in micro-fluidic chip, how to make sample easily and effectively reach the technology barrier that the predetermined area is micro-fluidic chip.Traditional micro-fluidic input mode is mainly divided into machine auto injection and hand sampling.Machine auto injection needs the assistance of specific apparatus just can complete sample introduction, such as flowing of liquid in the power supply unit driving chip by special, the operability of this micro-fluidic chip has very large limitation, need to provide the instrument of special construction to assist: chip sample introduction cannot depart from power supply unit, but drive the mobile equipment volume of chip inner fluid greatly and Ben Chong ﹑ complex structure though chip volume is little, manufacturing cost is high, energy consumption is high, be not suitable for very much the real-time detection in scene in non-laboratory, thereby the scope of application and the convenience of micro-fluidic chip have been reduced greatly, hand sampling needs to continue donation power to maintain sample introduction requirement and liquid holdup, and guarantee liquid can not reflux after entering reaction tank, thereby has greatly increased complexity and the sample introduction difficulty of operation.Some chips by two can deformation ball push the liquid in liquid storage tank, this chip is complex structure not only, cost is high, need special instrument to be controlled, and can in sample introduction, easily there is the situation of leakage by deformation ball, when can deformation ball entering into liquid storage tank bottom, liquid storage tank upper exposed out, easily pollutes and dangerous.
Utility model content
The purpose of this utility model be to provide a kind of have can deformation film anti-return micro-fluidic chip, while using the utility model, without continuous action power, can prevent liquid backflow.
Provided by the utility model have can deformation film anti-return micro-fluidic chip, it comprises a semiclosed micro-fluidic chip; Described semiclosed micro-fluidic chip is provided with liquid storage tank, reaction tank and pore, and all by fluid passage, is connected between described liquid storage tank and described reaction tank and between described reaction tank and described pore;
Described micro-fluidic chip also comprises that one can deformation epiphragma, and the described top of can deformation epiphragma being located at described liquid storage tank can deformation epiphragma generation deformation time, can drive the liquid in described liquid storage tank to flow in described reaction tank when described.
In above-mentioned micro-fluidic chip, described top that can deformation epiphragma is provided with cover plate, described cover plate is provided with the described structure that can deformation epiphragma of extruding, when described structure is extruded, described can being subject to the extruding of described structure and deformation occurs by deformation epiphragma, drives the liquid in described liquid storage tank to flow in described reaction tank.
In above-mentioned micro-fluidic chip, the described structure that can deformation epiphragma of extruding is projection or helicitic texture.
In above-mentioned micro-fluidic chip, the above and below of described liquid storage tank is equipped with magnet, and when described magnet attracts each other, described can being squeezed and deformation occurs by deformation epiphragma, drives the liquid in described liquid storage tank to flow in described reaction tank.
In above-mentioned micro-fluidic chip, describedly can be provided with cover plate by deformation epiphragma, on described cover plate, be provided with helicitic texture with the corresponding position of described liquid storage tank, when bolt arrangement coordinates with described helicitic texture, described can being squeezed and deformation occurs by deformation epiphragma, drives the liquid in described liquid storage tank to flow in described reaction tank;
The height of described bolt arrangement is greater than the height of described helicitic texture.
In above-mentioned micro-fluidic chip, described reaction tank is connected with one or more described pores.
In the utility model, material that can deformation epiphragma can be that sealed membrane, PVC film, alloy etc. are any has a retractility and can deformation but material irrecoverable or that part is recovered.
In the utility model, described liquid storage tank can be arbitrary shape and can independently exist, and each liquid storage tank connects by fluid passage, and each liquid storage tank is connecting respectively reaction tank; Or liquid storage tank is an integral unit, connects different reaction tanks.
The material of micro-fluidic chip of the present utility model can be glass, PDMS, PMMA, PET or PC.
While utilizing the utility model micro-fluidic chip to carry out hand sampling detection, can carry out in accordance with the following steps:
Make to be arranged at can be subject to producing deformation after active force by deformation epiphragma on liquid storage tank, force liquid in liquid storage tank by fluid passage, enter in reaction tank and remain in reaction tank, after active force stops, can the deformation of deformation epiphragma partly recover or not recover, in reaction tank, liquid can not be back in liquid storage tank.The above-mentioned liquid being squeezed out from liquid storage tank flows to predeterminated target reaction tank by the fluid passage of coupled reaction pond and liquid storage tank.
Specifically can be by the special construction instrument by matching with liquid storage tank shape or only with finger, press to press and make epiphragma generation deformation, force liquid storage tank liquid to enter reaction tank.
The utility model micro-fluidic chip tool has the following advantages:
When liquid detecting reaction is carried out, and can control voluntarily decision by experimenter; Do not need complicated instrument and equipment, Wu Beng ﹑ valveless, device structure is simple, and dependable performance is easily implemented; Chip is disposable use, and cost is low, can not occur pollution condition because reusing; Chip maintains sample introduction and requires and liquid holdup without giving lasting sample introduction pressure, after giving the of short duration active force of single, can remove active force and carry out complete operation, not only the amount of liquid that enters reaction tank can be controlled, multistage liquid reactions can also be carried out on demand successively.Liquid can not reflux after entering reaction tank, has greatly optimized the method for operating that needs continuous action power guarantee chip to work on.
Accompanying drawing explanation
Fig. 1, Fig. 2, the microfluidic chip structure schematic diagram that Fig. 3 provides for embodiment of the present invention 1-3.
The microfluidic chip structure schematic diagram that Fig. 4 provides for the embodiment of the present invention 4.
The microfluidic chip structure schematic diagram that Fig. 5 provides for the embodiment of the present invention 4.
The microfluidic chip structure schematic diagram that Fig. 6 provides for the embodiment of the present invention 4.
The microfluidic chip structure schematic diagram that Fig. 7 provides for the embodiment of the present invention 7.
The microfluidic chip structure schematic diagram that Fig. 8 provides for the embodiment of the present invention 8.
The microfluidic chip structure schematic diagram that Fig. 9 provides for the embodiment of the present invention 9.
In figure, each mark is as follows:
A injection port, B liquid storage tank, C reaction tank, D, F fluid passage, E pore, G chip, H epiphragma, I cover plate, J and the corresponding position of magnet, K magnet, L helicitic texture, M bolt arrangement, N magnet.
The specific embodiment
Below in conjunction with accompanying drawing, the utility model is described further, but the utility model is not limited to following examples.
Embodiment 1,
The top view of the micro-fluidic chip that the present embodiment provides as shown in Figure 1, wherein semiclosed chip comprises injection port A, liquid storage tank B, reaction tank C, pore E, connects liquid storage tank B and fluid passage D, the coupled reaction pond C of reaction tank C and the passage F of pore E that (liquid storage tank B, reaction tank C, pore E, fluid passage D and F Wei Yige unit can exist the reacton of one or more quantity on chip) all communicates with the external world; Can be located at the top of liquid storage tank B by deformation epiphragma, and must cover liquid storage tank.When liquid is from injection port A sample introduction, seal injection port A simultaneously.When can deformation epiphragma generation deformation, can drive the liquid in liquid storage tank B to flow in reaction tank C.
Can directly with finger, press pressure liquid storage tank, make can be subject to produce deformation after active force in one's hands by deformation epiphragma on liquid storage tank, force liquid in liquid storage tank by fluid passage, enter in reaction tank and remain in reaction tank, after above-mentioned active force removes, can the deformation of deformation epiphragma can not recover or part recovery, in reaction tank, liquid can not be back in liquid storage tank, reaction tank can be full of by liquid or not be filled, make the fixing needed reagent of biochemical reaction in sample and reaction tank carry out for example enzyme reaction, immune response, PCR reaction, the reactions such as ELISA (ELISA).
Embodiment 2,
The top view of the micro-fluidic chip that the present embodiment provides as shown in Figure 2, wherein semiclosed chip comprises that injection port A, liquid storage tank B, reaction tank C, pore E, connection liquid storage tank B and fluid passage D, the coupled reaction pond C of reaction tank C and the passage F of pore E (liquid storage tank B, reaction tank C, pore E, fluid passage D and F Wei Yige unit exist 3 reactons on this chip) all communicate with the external world, the top that can deformation epiphragma be located at liquid storage tank B, and must cover liquid storage tank, other parts of chip can be used can compressional deformation epiphragma, also can use non-deformation epiphragma, the cover plate matching with liquid storage tank B, on described cover plate, be provided with the special construction of extruding epiphragma, when cover plate covers chip, epiphragma is subject to after cover plate active force generation deformation, force liquid in liquid storage tank by fluid passage, enter in reaction tank and remain in reaction tank, cover plate can be retained on chip and not remove or remove, after removing cover plate, epiphragma deformation can not recover or part is recovered, in reaction tank, liquid can not be back in liquid storage tank, reaction tank can be full of by liquid or not be filled, make the fixing needed reagent of biochemical reaction in sample and reaction tank carry out for example enzyme reaction, immune response, PCR reaction, the reactions such as ELISA (ELISA).
Embodiment 3,
As shown in Figure 3, the chip structure shown in its structure and Fig. 2 is similar for the micro-fluidic chip top view that the present embodiment provides, and difference is: in the present embodiment, 3 reaction members share a liquid storage tank B, be arranged at the pushed epiphragma above liquid storage tank, can push epiphragma and must cover liquid storage tank, other parts of chip can be used can compressional deformation epiphragma, also can use non-deformation epiphragma, the cover plate matching with liquid storage tank can be set, on cover plate, be provided with the special construction of extruding epiphragma, when cover plate covers chip, epiphragma is subject to after cover plate active force generation deformation, force liquid in liquid storage tank by fluid passage, enter in reaction tank and remain in reaction tank, cover plate can be retained on chip and not remove or remove, after removing cover plate, epiphragma deformation can not recover or part is recovered, in reaction tank, liquid can not be back in liquid storage tank, reaction tank can be full of by liquid or not be filled, make the fixing needed reagent of biochemical reaction in sample and reaction tank carry out for example enzyme reaction, immune response, PCR reaction, the reactions such as ELISA (ELISA).
Embodiment 4,
As shown in Figure 4, the chip structure shown in its structure and Fig. 1 is similar for the micro-fluidic chip top view that the present embodiment provides, and difference is: 3 reaction tank C are set in the present embodiment, are series winding between them.Be arranged at the pushed epiphragma above liquid storage tank, can push epiphragma and must cover liquid storage tank, other parts of chip can be used can compressional deformation epiphragma, also can use non-deformation epiphragma, the cover plate matching with liquid storage tank can be set, on cover plate, be provided with the special construction of extruding epiphragma, when cover plate covers chip, epiphragma is subject to after cover plate active force generation deformation, force liquid in liquid storage tank by fluid passage, enter in reaction tank and remain in reaction tank, cover plate can be retained on chip and not remove or remove, after removing cover plate, epiphragma deformation can not recover or part is recovered, in reaction tank, liquid can not be back in liquid storage tank, reaction tank can be full of by liquid or not be filled, make the fixing needed reagent of biochemical reaction in sample and reaction tank carry out for example enzyme reaction, immune response, PCR reaction, the reactions such as ELISA (ELISA).
Embodiment 5,
The micro-fluidic chip top view that the present embodiment provides as shown in Figure 5, the structure of the chip shown in its structure and Fig. 1 is similar, difference is: in the present embodiment, omission arranges injection port A, liquid storage tank B is that closed state exists, in liquid storage tank B, liquid stay is for reaction in advance, and all the other operating procedures are with embodiment 1.
Embodiment 6,
The micro-fluidic chip top view that the present embodiment provides as shown in Figure 6, the structure of the chip shown in its structure and Fig. 2 is similar, difference is: a pore E is only set in the present embodiment, this pore E by and each reaction tank C between fluid passage F share, all the other operating procedures are with embodiment 1.
Embodiment 7,
The micro-fluidic chip that the present embodiment provides as shown in Figure 7, the structure of the chip shown in its structure and Fig. 1 is similar, difference is: in the present embodiment, also comprise an epiphragma H, it is arranged at above liquid storage tank and must covers liquid storage tank, other parts of chip can be used deformation epiphragma, also can use non-deformation epiphragma.Above epiphragma H with below chip G, a magnet K is all being set, and one and the corresponding position J of magnet are set on epiphragma H, when magnet K attracts each other, make epiphragma H that deformation occur, thereby make liquid storage tank B that deformation occur, force liquid in liquid storage tank by fluid passage, enter in reaction tank and remain in reaction tank, magnet K is because magneticaction can not separate, cause liquid storage tank deformation can not recover, thereby in reaction tank, liquid can not be back in liquid storage tank, reaction tank can be full of by liquid or not be filled, make the fixing needed reagent of biochemical reaction in sample and reaction tank carry out for example enzyme reaction, immune response, PCR reaction, the reactions such as ELISA (ELISA).
Embodiment 8,
The micro-fluidic chip that the present embodiment provides as shown in Figure 8, structure shown in its structure and Fig. 7 is similar, difference is: in the present embodiment, the magnet K that is arranged at epiphragma H top is arranged on cover plate I, magnet N is set simultaneously below chip, after chip energising, electromagnet N produces magnetic, attract magnet K, because magnet N and magnet K attract each other, liquid storage tank generation deformation, force liquid in liquid storage tank by fluid passage, enter in reaction tank and remain in reaction tank, magnet N with magnet K because magneticaction can not separate, cause liquid storage tank deformation can not recover or part recovery, thereby in reaction tank, liquid can not be back in liquid storage tank, reaction tank can be full of by liquid or not be filled, make the fixing needed reagent of biochemical reaction in sample and reaction tank carry out for example enzyme reaction, immune response, PCR reaction, the reactions such as ELISA (ELISA).
Embodiment 9,
The micro-fluidic chip that the present embodiment provides as shown in Figure 9, structure shown in its structure and Fig. 8 is similar, difference is: in the present embodiment, omit the setting of magnet N and magnet K, helicitic texture L is set simultaneously on cover plate I, bolt arrangement M can enter by the helicitic texture L on cover plate I in liquid storage tank B, thereby change the spatial volume of liquid storage tank, force liquid in liquid storage tank to enter in reaction tank C, the volume that bolt arrangement M enters liquid storage tank B can regulate according to reaction tank liquid demand, play the effect that liquid storage tank enters into the amount of liquid of reaction tank of controlling, in simultaneous reactions pond, liquid can not be back in liquid storage tank, reaction tank can be full of by liquid or not be filled, make the fixing needed reagent of biochemical reaction in sample and reaction tank carry out for example enzyme reaction, immune response, PCR reaction, the reactions such as ELISA (ELISA).
Claims (6)
1. have can deformation film anti-return a micro-fluidic chip, it is characterized in that: it comprises a semiclosed micro-fluidic chip; Described semiclosed micro-fluidic chip is provided with liquid storage tank, reaction tank and pore, and all by fluid passage, is connected between described liquid storage tank and described reaction tank and between described reaction tank and described pore;
Described micro-fluidic chip also comprises that one can deformation epiphragma, and the described top of can deformation epiphragma being located at described liquid storage tank can deformation epiphragma generation deformation time, can drive the liquid in described liquid storage tank to flow in described reaction tank when described.
2. micro-fluidic chip according to claim 1, it is characterized in that: described top that can deformation epiphragma is provided with cover plate, described cover plate is provided with the described structure that can deformation epiphragma of extruding, when described structure is extruded, described can being subject to the extruding of described structure and deformation occurs by deformation epiphragma, drives the liquid in described liquid storage tank to flow in described reaction tank.
3. micro-fluidic chip according to claim 2, is characterized in that: the described structure that can deformation epiphragma of extruding is projection or helicitic texture.
4. micro-fluidic chip according to claim 1, it is characterized in that: the above and below of described liquid storage tank is equipped with magnet, when described magnet attracts each other, described can being squeezed and deformation occurs by deformation epiphragma, drives the liquid in described liquid storage tank to flow in described reaction tank.
5. micro-fluidic chip according to claim 1, it is characterized in that: describedly can be provided with cover plate by deformation epiphragma, on described cover plate, be provided with helicitic texture with the corresponding position of described liquid storage tank, when bolt arrangement coordinates with described helicitic texture, described can being squeezed and deformation occurs by deformation epiphragma, drives the liquid in described liquid storage tank to flow in described reaction tank;
The height of described bolt arrangement is greater than the height of described helicitic texture.
6. according to the micro-fluidic chip described in any one in claim 1-5, it is characterized in that: described reaction tank is connected with one or more described pores.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420272519.0U CN203842597U (en) | 2014-05-26 | 2014-05-26 | Micro-fluidic chip with deformable membrane capable of preventing reflux |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420272519.0U CN203842597U (en) | 2014-05-26 | 2014-05-26 | Micro-fluidic chip with deformable membrane capable of preventing reflux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203842597U true CN203842597U (en) | 2014-09-24 |
Family
ID=51555661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420272519.0U Active CN203842597U (en) | 2014-05-26 | 2014-05-26 | Micro-fluidic chip with deformable membrane capable of preventing reflux |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203842597U (en) |
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105170206A (en) * | 2015-09-24 | 2015-12-23 | 基蛋生物科技股份有限公司 | Micro-fluidic chip achieving multi-index detection |
| CN105214745A (en) * | 2015-10-26 | 2016-01-06 | 深圳华迈兴微医疗科技有限公司 | A kind of micro-fluidic chip |
| CN106902905A (en) * | 2017-04-01 | 2017-06-30 | 苏州岚轩生物科技有限公司 | Back-flow preventer and its micro-fluidic chip are controlled for micro-fluidic chip liquid |
| CN109578690A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| CN109578685A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| CN109578687A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| CN109578686A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| CN109578688A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| CN109578689A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| CN109622083A (en) * | 2019-01-24 | 2019-04-16 | 京东方科技集团股份有限公司 | A kind of microfluidic system and preparation method thereof |
| CN110452814A (en) * | 2019-07-12 | 2019-11-15 | 北京资和源医疗科技有限公司 | A kind of PCR fast reaction chip |
| CN110918142A (en) * | 2014-12-08 | 2020-03-27 | 伯克利之光生命科技公司 | Directional flow actuated microfluidic structures in microfluidic devices and methods of using the same |
| CN111822064A (en) * | 2019-10-09 | 2020-10-27 | 京东方科技集团股份有限公司 | Microfluidic substrate and microfluidic chip |
| CN112143784A (en) * | 2020-09-29 | 2020-12-29 | 生物岛实验室 | Space omics sequencing, single-cell apparent transcriptomics sequencing and positioning identification method |
| CN112337516A (en) * | 2020-09-18 | 2021-02-09 | 东莞东阳光医疗智能器件研发有限公司 | Air pressure balance micro-fluidic chip and control method thereof |
| CN112547142A (en) * | 2019-09-25 | 2021-03-26 | 深圳市刚竹医疗科技有限公司 | Liquid storage structure for centrifugal liquid release and centrifugal micro-fluidic chip |
| US11162488B2 (en) | 2017-09-29 | 2021-11-02 | Microjet Technology Co., Ltd. | Fluid system |
| US11193479B2 (en) | 2017-09-29 | 2021-12-07 | Microjet Technology Co., Ltd. | Fluid system |
| US11204027B2 (en) | 2017-09-29 | 2021-12-21 | Microjet Technology Co., Ltd. | Fluid system |
-
2014
- 2014-05-26 CN CN201420272519.0U patent/CN203842597U/en active Active
Cited By (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11192108B2 (en) | 2014-12-08 | 2021-12-07 | Berkeley Lights, Inc. | Actuated microfluidic structures for directed flow in a microfluidic device and methods of use thereof |
| CN110918142A (en) * | 2014-12-08 | 2020-03-27 | 伯克利之光生命科技公司 | Directional flow actuated microfluidic structures in microfluidic devices and methods of using the same |
| CN105170206A (en) * | 2015-09-24 | 2015-12-23 | 基蛋生物科技股份有限公司 | Micro-fluidic chip achieving multi-index detection |
| CN105170206B (en) * | 2015-09-24 | 2017-06-16 | 基蛋生物科技股份有限公司 | A kind of micro-fluidic chip of multiple determination |
| CN105214745A (en) * | 2015-10-26 | 2016-01-06 | 深圳华迈兴微医疗科技有限公司 | A kind of micro-fluidic chip |
| CN106902905A (en) * | 2017-04-01 | 2017-06-30 | 苏州岚轩生物科技有限公司 | Back-flow preventer and its micro-fluidic chip are controlled for micro-fluidic chip liquid |
| CN109578687A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| CN109578686B (en) * | 2017-09-29 | 2021-07-27 | 研能科技股份有限公司 | Fluid system |
| CN109578688A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| CN109578689A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| CN109578686A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| CN109578685A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| US11204027B2 (en) | 2017-09-29 | 2021-12-21 | Microjet Technology Co., Ltd. | Fluid system |
| CN109578690A (en) * | 2017-09-29 | 2019-04-05 | 研能科技股份有限公司 | Fluid system |
| US11193479B2 (en) | 2017-09-29 | 2021-12-07 | Microjet Technology Co., Ltd. | Fluid system |
| US11162488B2 (en) | 2017-09-29 | 2021-11-02 | Microjet Technology Co., Ltd. | Fluid system |
| CN109578685B (en) * | 2017-09-29 | 2021-07-27 | 研能科技股份有限公司 | Fluid system |
| CN109622083A (en) * | 2019-01-24 | 2019-04-16 | 京东方科技集团股份有限公司 | A kind of microfluidic system and preparation method thereof |
| CN110452814A (en) * | 2019-07-12 | 2019-11-15 | 北京资和源医疗科技有限公司 | A kind of PCR fast reaction chip |
| CN112547142A (en) * | 2019-09-25 | 2021-03-26 | 深圳市刚竹医疗科技有限公司 | Liquid storage structure for centrifugal liquid release and centrifugal micro-fluidic chip |
| CN111822064A (en) * | 2019-10-09 | 2020-10-27 | 京东方科技集团股份有限公司 | Microfluidic substrate and microfluidic chip |
| CN112337516A (en) * | 2020-09-18 | 2021-02-09 | 东莞东阳光医疗智能器件研发有限公司 | Air pressure balance micro-fluidic chip and control method thereof |
| CN112337516B (en) * | 2020-09-18 | 2022-04-29 | 东莞东阳光医疗智能器件研发有限公司 | Air pressure balance micro-fluidic chip and control method thereof |
| CN112143784A (en) * | 2020-09-29 | 2020-12-29 | 生物岛实验室 | Space omics sequencing, single-cell apparent transcriptomics sequencing and positioning identification method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN203842597U (en) | Micro-fluidic chip with deformable membrane capable of preventing reflux | |
| CN103861668B (en) | Microfluidic chip based on pneumatic micro pumps and micro mixer | |
| CN203899622U (en) | Micro-fluidic chip | |
| CN101458249B (en) | Microfluid example boat with solution storage chamber and pump structure | |
| CN106902904B (en) | For the liquid control valve door gear and its micro-fluidic chip of micro-fluidic chip | |
| CN107703320B (en) | Fully-integrated multi-channel multifunctional microfluidic analysis experiment system | |
| CN102735864A (en) | Hand-operated air pressure sample introduction method for microfluidic chips | |
| CN208224063U (en) | Chip reaction unit and water quality many reference amounts detection device based on chip reaction unit | |
| CN102259040A (en) | High-throughput micro-droplet fixing method and special micro-fluidic chip thereof | |
| CN105441308A (en) | A circulating type single-cell capturing chip | |
| Kim et al. | Motorized smart pipette for handheld operation of a microfluidic blood plasma separator | |
| CN204448036U (en) | A kind of micro-fluidic chip | |
| CN101452003B (en) | Liquid storage pool micropump completely-integrated in micro-fluidic chip | |
| CN104148124B (en) | A kind of drop formation device for micro-fluidic chip | |
| CN103041877A (en) | Photo-response micro-fluid self-driven micro-fluidic chip and preparation method thereof | |
| CN207611061U (en) | A kind of micro-fluidic chip sampling device based on over-pressure control | |
| CN103801415A (en) | Button type microfluid control system and button type microfluid control method | |
| CN110470601A (en) | Water quality many reference amounts detection device and detection method based on chip reaction unit | |
| CN103308502A (en) | Handheld general microfluidic chip real-time detection device and application | |
| CN103614292A (en) | Micro-fluidic chip for biologic PCR (Polymerase Chain Reaction) fluorescent quantitation | |
| CN115678765B (en) | Microfluidic chip suitable for molecular diagnosis | |
| CN103586094B (en) | Micro-fluidic chip with circulation mixed structure and circulation mixed method | |
| CN103071554A (en) | Microfluidic chip for circularly driving solution and preparation method thereof | |
| CN101968131B (en) | Capillary micro valve based on phase-substituted triggering and application thereof | |
| CN205015354U (en) | Reagent encapsulates micro -fluidic chip in advance and experiment appearance thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |