CN203824968U - Connection system and device for liquid chromatogram or ion chromatograph and inductively coupled plasma source mass spectrometer - Google Patents
Connection system and device for liquid chromatogram or ion chromatograph and inductively coupled plasma source mass spectrometer Download PDFInfo
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- CN203824968U CN203824968U CN201320880274.5U CN201320880274U CN203824968U CN 203824968 U CN203824968 U CN 203824968U CN 201320880274 U CN201320880274 U CN 201320880274U CN 203824968 U CN203824968 U CN 203824968U
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- connecting port
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- ion chromatograph
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- 239000007788 liquid Substances 0.000 title claims abstract description 19
- 238000009616 inductively coupled plasma Methods 0.000 title abstract description 35
- 238000004811 liquid chromatography Methods 0.000 claims description 49
- 238000004140 cleaning Methods 0.000 claims description 16
- 239000002699 waste material Substances 0.000 claims description 10
- 239000004696 Poly ether ether ketone Substances 0.000 claims description 4
- JUPQTSLXMOCDHR-UHFFFAOYSA-N benzene-1,4-diol;bis(4-fluorophenyl)methanone Chemical compound OC1=CC=C(O)C=C1.C1=CC(F)=CC=C1C(=O)C1=CC=C(F)C=C1 JUPQTSLXMOCDHR-UHFFFAOYSA-N 0.000 claims description 4
- 239000012530 fluid Substances 0.000 claims description 4
- 229920002530 polyetherether ketone Polymers 0.000 claims description 4
- 230000002457 bidirectional effect Effects 0.000 claims description 3
- 238000001514 detection method Methods 0.000 abstract description 5
- 238000012360 testing method Methods 0.000 abstract description 5
- 238000004458 analytical method Methods 0.000 abstract description 4
- 238000002360 preparation method Methods 0.000 abstract description 3
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 description 13
- 238000010168 coupling process Methods 0.000 description 10
- 230000008878 coupling Effects 0.000 description 8
- 238000005859 coupling reaction Methods 0.000 description 8
- 238000013467 fragmentation Methods 0.000 description 3
- 238000006062 fragmentation reaction Methods 0.000 description 3
- 229910021642 ultra pure water Inorganic materials 0.000 description 3
- 239000012498 ultrapure water Substances 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000004587 chromatography analysis Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000000589 high-performance liquid chromatography-mass spectrometry Methods 0.000 description 1
- 238000001095 inductively coupled plasma mass spectrometry Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000000918 plasma mass spectrometry Methods 0.000 description 1
- 238000012113 quantitative test Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
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- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
The utility model relates to the technical field of analysis and detection and discloses a connection system and a connection device for a liquid chromatogram (LC) or an ion chromatograph (IC) and an inductively coupled plasma source mass spectrometer (ICP/MS). The connection system and device are suitable for connecting the LC or the IC and the ICP/MS. Based on the connection system and device, when a testing instrument is converted into a preparation or working state from a pre-heating or balancing state or an instrument tuning state each time, a pipeline outlet end of the LC or the IC does not need to be manually inserted into an inlet end of an ICP/MS atomizer, so that a liquid leaking phenomenon is avoided and the danger of crushing the atomizer is also reduced.
Description
Technical field
The utility model relates to technical field of analysis and detection, more specifically, relates to a kind of for liquid chromatography or ion chromatograph and icp ms connected system and device.
Background technology
Inductivity coupled plasma mass spectrometry (ICP-MS) because of the sensitivity of its superelevation become ultimate analysis selectivity analyze effective means, and liquid chromatography (LC) or chromatography of ions (IC) and ICP-MS coupling, detecting device by ICP-MS as liquid chromatography or chromatography of ions, follow the tracks of the signal intensity of tested element isotope in each form, to make chromatogram become simply, and contribute to the confirmation of element morphology and carry out quantitative test.Current described coupling technique becomes the mainstream technology in the Elemental Speciation Analysis of environment, material and bio-science sample.
But; in actual analyzing and testing operation; each test apparatus is converted to and is prepared or when duty by preheating or equilibrium state or instrument tuning state; all need manually the pipe outlet of LC or IC to be inserted the inlet end of ICP/MS instrument atomizer; if LC or IC instrument are not shut down, the pipe outlet of LC or IC easily produces the phenomenon of leakage in the inlet end process of inserting ICP/MS instrument atomizer.With this simultaneously, because ICP/MS instrument atomizer is more crisp frangible, when manual operation, there is the danger of atomizer fragmentation.
Summary of the invention
The purpose of this utility model, for the deficiency of the coupling arrangement in high performance liquid chromatography and Inductively coupled plasma mass spectrometry coupling technique, provides a kind of for liquid chromatography or ion chromatograph and icp ms connected system.
Another object to be solved in the utility model is to provide for liquid chromatography or ion chromatograph and icp ms coupling arrangement.
The purpose of this utility model is achieved through the following technical solutions above-mentioned purpose:
Provide a kind of for liquid chromatography or ion chromatograph and icp ms connected system, comprise be arranged at liquid chromatography or ion chromatograph connecting port 31, be arranged at waste collecting device connecting port 32, be arranged at cleaning fluid or tuning liquid device connecting port 33, be arranged at the connecting port 34 of icp ms; Between described connecting port 31 and 32,34, between 33 and 34, connect by connecting pipe; Described connecting port 31,32,33 and 34 is equipped with by-pass valve control.Wherein the by-pass valve control of connecting port 31 and 34 is bidirectional control valve door.
The utility model system is applicable to connect LC or IC instrument and ICP/MS.When LC or IC and ICP/MS instrument are in preheating or equilibrium state or instrument when tuning, by valve control, pipeline between connecting port 31 and 32,33 and 34 is communicated with, pipeline between 31 and 34 disconnects, the liquid that now LC or IC discharge is by the pipeline between 31 and 32 to waste liquid bottle, and when cleaning, ICP/MS instrument pumps into cleaning solution (ultrapure water or 5%HNO
3solution) carry out pipeline cleaning, when manual tuning, pump into tuning liquid to ICP/MS instrument by the pipeline between 33 and 34; (2) when LC or IC and ICP/MS instrument are in preparing or when duty, valve in device switches, pipeline between device 31 and 32,33 and 34 is disconnected, pipeline between 31 and 34 is communicated with, now can realize the on-line coupling of LC or IC and ICP/MS instrument, LC or IC are sample introduction and piece-rate system, and ICP/MS is detection and data acquisition, analytic system.
For more convenient to use, it is a kind of for liquid chromatography or ion chromatograph and icp ms coupling arrangement that the utility model provides, and described device comprises four connecting ports 31,32,33 and 34;
Connecting port 31 one end arrange connecting pipe and connect LC or IC instrument, and the other end arranges different connecting pipes and connects respectively connecting port 32 and 34;
Connecting port 32 one end arrange connecting pipe and are connected with waste collecting device, and the other end arranges connecting pipe and connects connecting port 31;
Connecting port 34 one end arrange connecting pipe and connect ICP/MS instrument, and the other end arranges different connecting pipes and connects respectively connecting port 31 and 33;
Connecting port 33 one end arrange connecting pipe and connect cleaning solution or tuning liquid device, and the other end arranges connecting pipe and connects connecting port 34;
Described four connecting ports are respectively equipped with by-pass valve control, and wherein connecting port 31 and 34 places are set to two-way switching valve door.
Preferably, described device also comprises shell, and shell is provided with four connecting ports, is connected respectively with LC or IC instrument, ICP/MS instrument, waste collecting device and the connecting pipe of cleaning fluid or tuning liquid device.
Preferably, described connecting tube adopts PEEK pipe to connect, and carries out the operation of both instruments by the built-in LC of ICP-MS function software or IC control.Between LC or IC and ICP-MS, be connected by PEEK pipe, keep away
That has exempted from that mobile phase causes through metal material stains.
The beneficial effects of the utility model:
The utility model has designed a kind of coupling arrangement, is applicable to connect LC or IC instrument and ICP/MS.Based on the utility model, each test apparatus is converted to and is prepared or when duty by preheating or equilibrium state or instrument tuning state, no longer need manually the pipe outlet of LC or IC to be inserted the inlet end of ICP/MS instrument atomizer, avoid the generation of the phenomenon of leakage, also reduced the danger of atomizer fragmentation simultaneously.
Brief description of the drawings
System architecture schematic diagram when Fig. 1 preheating or equilibrium state or instrument are tuning.
Fig. 2 instrument is system architecture schematic diagram in the time of preparation or duty.
Structural representation when preheating or equilibrium state or instrument are tuning after Fig. 3 the utility model device is connected with pertinent instruments.
Instrument structural representation in the time of preparation or duty after Fig. 4 the utility model device is connected with pertinent instruments.
Fig. 5 the utility model crust of the device structural representation.
Embodiment
Further describe the utility model below in conjunction with the drawings and specific embodiments, unless stated otherwise, the reagent that the present invention adopts and equipment are the conventional commercial reagent in this area and conventional equipment.
Embodiment 1
See shown in accompanying drawing 1 and accompanying drawing 2.Connection solid line between connected system connecting port is connected state, and connection dotted line is off-state.
It is a kind of for liquid chromatography or ion chromatograph and icp ms connected system that the present embodiment provides, comprise be arranged at liquid chromatography or ion chromatograph connecting port 31, be arranged at waste collecting device connecting port 32, be arranged at cleaning fluid or tuning liquid device connecting port 33, be arranged at the connecting port 34 of icp ms; Between described connecting port 31 and 32,34, between 33 and 34, connect by connecting pipe.
Described connecting port 31,32,33 and 34 is equipped with by-pass valve control.Wherein the by-pass valve control of connecting port 31 and 34 is bidirectional control valve door.
Native system is applicable to connect LC or IC instrument 1 and ICP/MS 2.When LC or IC instrument 1 and ICP/MS instrument 2 are in preheating or equilibrium state or instrument when tuning, by valve control, pipeline between connecting port 31 and 32,33 and 34 is communicated with, pipeline between 31 and 34 disconnects, the liquid that now LC or IC instrument 1 are discharged is by the pipeline between 31 and 32 to waste liquid bottle 5, and when cleaning, ICP/MS instrument 2 pumps into cleaning solution (ultrapure water or 5%HNO
3solution) 4 carry out pipeline cleaning, when manual tuning, pump into tuning liquid to ICP/MS instrument 2 by the pipeline between 33 and 34; When LC or IC instrument 1 and ICP/MS instrument 2 are in preparing or when duty, valve in device switches, pipeline between device 31 and 32,33 and 34 is disconnected, pipeline between 31 and 34 is communicated with, now can realize the on-line coupling of LC or IC instrument 1 and ICP/MS instrument 2, LC or IC are sample introduction and piece-rate system, and ICP/MS is detection and data acquisition, analytic system.
Embodiment 2
See shown in accompanying drawing 3 and accompanying drawing 4.Connection solid line in connected system or device before connecting port is connected state, and connection dotted line is off-state.
The present embodiment provides a kind of device 3 being connected with icp ms for liquid chromatography or ion chromatograph, and device 3 comprises four connecting ports 31,32,33 and 34;
Connecting port 31 one end connect LC or IC instrument by connecting pipe, and the other end connects respectively connecting port 32 and 34 by different connecting pipes;
Connecting port 32 is connected with waste collecting device by connecting pipe by one end, and the other end connects connecting port 31 by connecting pipe;
Connecting port 34 one end connect ICP/MS instrument by connecting pipe, and the other end connects respectively connecting port 31 and 33 by different connecting pipes;
Connecting port 33 one end connect cleaning solution or tuning liquid device by connecting pipe, and the other end connects connecting port 34 by connecting pipe;
Described four connecting ports are respectively equipped with by-pass valve control, and wherein connecting port 31 and 34 places are set to two-way switching valve door.
Device 3 is applicable to connect LC or IC instrument 1 and ICP/MS instrument 2.When LC or IC instrument 1 and ICP/MS instrument 2 are in preheating or equilibrium state or instrument when tuning, by valve control, pipeline between connecting port 31 and 32,33 and 34 is communicated with, pipeline between 31 and 34 disconnects, the liquid that now LC or IC instrument 1 are discharged is by the pipeline between 31 and 32 to waste liquid bottle 5, and when cleaning, ICP/MS instrument 2 pumps into cleaning solution (ultrapure water or 5%HNO
3solution) 4 carry out pipeline cleaning, when manual tuning, pump into tuning liquid to ICP/MS instrument 2 by the pipeline between 33 and 34; When LC or IC instrument 1 and ICP/MS instrument 2 are in preparing or when duty, valve in device switches, pipeline between device 31 and 32,33 and 34 is disconnected, pipeline between 31 and 34 is communicated with, now can realize the on-line coupling of LC or IC instrument 1 and ICP/MS instrument 2, LC or IC are sample introduction and piece-rate system, and ICP/MS is detection and data acquisition, analytic system.
This device can also comprise shell, and becoming is a complete structural device, and connecting line is arranged in shell, and the outer indwelling connecting port of shell and by-pass valve control, be shown in shown in accompanying drawing 5, and overall appearance after connection corresponding instrument is easy to use.
Adjust for convenient inspection, described shell is also detachable.
The system providing based on the utility model or device, each test apparatus is converted to and is prepared or when duty by preheating or equilibrium state or instrument tuning state, no longer need manually the pipe outlet of LC or IC to be inserted the inlet end of ICP/MS instrument atomizer, avoid the generation of the phenomenon of leakage, also reduced the danger of atomizer fragmentation simultaneously.
Claims (5)
1. one kind for liquid chromatography or ion chromatograph and icp ms connected system, it is characterized in that, described system comprise be arranged at liquid chromatography or ion chromatograph connecting port 1 (31), be arranged at waste collecting device connecting port 2 (32), be arranged at cleaning fluid or tuning liquid device connecting port 3 (33), be arranged at the connecting port 4 (34) of icp ms; Between described connecting port 1 (31) and connecting port 2 (32), connecting port 4 (34), connect by connecting pipe between connecting port 3 (33) and connecting port 4 (34); Described connecting port 1 (31), connecting port 2 (32), connecting port 3 (33) and connecting port 4 (34) are equipped with by-pass valve control; Wherein the by-pass valve control of connecting port 1 (31) and connecting port 4 (34) is bidirectional control valve door.
2. according to claim 1 for liquid chromatography or ion chromatograph and icp ms connected system, it is characterized in that, described connecting pipe adopts PEEK pipe.
3. the device being connected with icp ms for liquid chromatography or ion chromatograph, it is characterized in that, described device comprises that four connecting ports are respectively connecting port 1 (31), connecting port 2 (32), connecting port 3 (33) and connecting port 4 (34);
Connecting port 1 (31) one end connects liquid chromatography or ion chromatograph by connecting pipe, and the other end connects respectively connecting port 2 (32) and connecting port 4 (34) by different connecting pipes;
Connecting port 2 (32) is connected with waste collecting device by connecting pipe by one end, and the other end connects connecting port 1 (31) by connecting pipe;
Connecting port 4 (34) one end connect icp ms by connecting pipe, and the other end connects respectively connecting port 1 (31) and connecting port 3 (33) by different connecting pipes;
Connecting port 3 (33) one end connect cleaning solution or tuning liquid device by connecting pipe, and the other end connects connecting port 4 (34) by connecting pipe;
Described four connecting ports are respectively equipped with by-pass valve control.
4. the device being connected with icp ms for liquid chromatography or ion chromatograph according to claim 3, is characterized in that, described device also comprises shell.
5. the device being connected with icp ms for liquid chromatography or ion chromatograph according to claim 3, is characterized in that, described connecting pipe adopts PEEK pipe.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320880274.5U CN203824968U (en) | 2013-12-30 | 2013-12-30 | Connection system and device for liquid chromatogram or ion chromatograph and inductively coupled plasma source mass spectrometer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320880274.5U CN203824968U (en) | 2013-12-30 | 2013-12-30 | Connection system and device for liquid chromatogram or ion chromatograph and inductively coupled plasma source mass spectrometer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203824968U true CN203824968U (en) | 2014-09-10 |
Family
ID=51480451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320880274.5U Expired - Lifetime CN203824968U (en) | 2013-12-30 | 2013-12-30 | Connection system and device for liquid chromatogram or ion chromatograph and inductively coupled plasma source mass spectrometer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203824968U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112378987A (en) * | 2021-01-18 | 2021-02-19 | 宁波华仪宁创智能科技有限公司 | Mass spectrometry system with cleaning function and method |
| CN115290808A (en) * | 2022-08-15 | 2022-11-04 | 北京市农林科学院 | Multifunctional LC-ICP-MS sample injection connection system and method |
-
2013
- 2013-12-30 CN CN201320880274.5U patent/CN203824968U/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112378987A (en) * | 2021-01-18 | 2021-02-19 | 宁波华仪宁创智能科技有限公司 | Mass spectrometry system with cleaning function and method |
| CN112378987B (en) * | 2021-01-18 | 2021-05-07 | 宁波华仪宁创智能科技有限公司 | Mass spectrometry system with cleaning function and method |
| CN115290808A (en) * | 2022-08-15 | 2022-11-04 | 北京市农林科学院 | Multifunctional LC-ICP-MS sample injection connection system and method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20140910 |
|
| CX01 | Expiry of patent term |