CN203606364U - Test strip card - Google Patents
Test strip card Download PDFInfo
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- CN203606364U CN203606364U CN201320722060.5U CN201320722060U CN203606364U CN 203606364 U CN203606364 U CN 203606364U CN 201320722060 U CN201320722060 U CN 201320722060U CN 203606364 U CN203606364 U CN 203606364U
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- examination bar
- bar
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- checking matter
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Abstract
The utility model belongs to the field of in-vitro diagnosis, and particularly relates to a test strip card which is provided with a storage medium (11) for storing a tested object standard curve, coefficient parameters or other detection information. The test strip card comprises a card box (3) and a test strip (2) in the card box (3), wherein a storage medium (11) is installed on the card box (3). When detecting a sample, an instrument with signal detection function acquires characteristic signals of a test strip (2) detection belt (6) and calculates the sample single component or multicomponent concentration in combination with the tested object standard curve or coefficient parameters simultaneously read from the storage medium (11) by the instrument. The test strip card for detecting samples has is simple and quick, and has the characteristics of high sensitivity, objective result, high use flexibility and the like.
Description
Technical field
The utility model belongs to in-vitro diagnosis field, be specifically related to a kind of self with storage medium 11 standby storage checking matter typical curve or coefficient parameter etc. for detections information, combination there is instrument energy fast detecting sample one-component or the multi-component examination bar card of signal testing function.
Background technology
The various aspects of immune detection have now been widely used in take colloid gold test strip as the immunity-chromatography test strip technology of main representative.This technology is simple and quick, and a few minutes just can obtain result.Weak point is: (1) can only qualitative detection sample, and difficulty can realize sample and quantitatively detect, the more difficult sample polycomponent Quantitative detection of realizing.(2) for some antigen or the extremely low sample of antibody content, be difficult to the naked eye judged result, detection sensitivity is low.
Adopting the quantitative checking matter concentration of checking matter standard items typical curve, is the main method of the quantitative sample concentration of current detection field.Standard curve making is technical strong, and process is numerous and diverse, be unable to do without professional and technical personnel.Message area is the storage medium of development recently, as RFID label (claiming again RFID tag), IC chip, magnetic code, bar code etc., has now been widely used in the fields such as computing machine, communication, electronics, business, communications and transportation control and management for Information Access identification.RFID label, volume is little, and storage information capacity is large, and identification need not manual intervention, the desirable means of Information Access identification especially, but few people use it for biomedical detection field.
For overcoming the deficiencies in the prior art, the utility model provide a kind of self with the information (not needing to make again checking matter typical curve when operating personnel detect sample) detections for such as the standby storage checking matter typical curve of storage medium 11 or coefficient parameter, just can realize fast the examination bar card of the quantitative detection of sample single component or polycomponent in conjunction with the instrument with signal testing function.The utility model is for sample detection, has easy quick, highly sensitive, the feature such as result is objective.
Utility model content
Technical solutions of the utility model are as follows:
Examination bar card described in the utility model comprises the examination bar 2 of cartridge 3 and Qi Nei.Examination bar 2 comprises that overlap joint is fixed on sample pad 4, label pad 5, analyzing film 7, the adsorptive pads 8 on end liner 1 in turn.Analyzing film 7 has to detect is with 6.Detection is with 6 to be one or more.The upper box face of cartridge 3 is having well 9 corresponding to examination bar sample pad 4 positions.The upper box face of cartridge 3 is having detection window 10 corresponding to examination bar analyzing film 7 positions.One storage medium 11 is installed in cartridge 3.
The a certain target checking matter that the label pad 5 of described examination bar 2 is coated with single labelled substance markers detects relevant single special molecular, or: the each target checking matter that is coated with different label correspondence markings detects the potpourri of relevant special molecular.
The detection of described examination bar 2 is coated with a certain target checking matter with 6 and detects another relevant special molecular, or: the potpourri that is coated with another special molecular that each target checking matter detection is relevant.
The checking matter typical curve that described storage medium 11 stores has various ways available, its include but not limited to checking matter standard items series concentration with
a detect bandbetween corresponding relation curve.Described
a detect bandbe defined as the detection band signal intensity that checking matter standard items series concentration records.
After the adsorptive pads 8 of examination bar 2 described in the utility model, can also be overlapped with an examination bar reaction end indicating label 12.Correspondingly, these examination bar reaction end indicating label 12 corresponding positions of its cartridge 3 have view window 13.Described examination bar reaction end indicating label 12 includes but not limited to that color change interval is the pH test paper of 5-9.
The label pad 5 of examination bar 2 described in the utility model is glass fibre membrane; The analyzing film 7 of described examination bar 2 is nitrocellulose filter, nylon membrane or cellulose nitrate/cellulose acetate hybrid films; The end liner 1 of described examination bar 2 is polyester or plastic plate; Described cartridge 3 is that polyester, plastics, rigid paper material or other materials are made.
Examination bar described in the utility model is stuck in examination bar checking matter and completes after the reaction of examination bar, and the detection that is gathered examination bar 2 in examination bar card by the instrument (as reading bar instrument, fluorescence detector, magnetic signal detector etc.) with signal testing function is read the checking matter typical curve that comes or coefficient parameter simultaneously and calculated and obtain sample single component or polycomponent concentration from storage medium 11 with 6 characteristic signals and in conjunction with this instrument.
The sample to be checked of examination bar card described in the utility model can be from clinical or non-clinical blood, body fluid, urine, saliva, genital secretion or other liquid samples or thick sample, wherein, the sample of clinical sample including infectious disease, hormone, cardiovascular disease, tumour, cancer, diabetes, autoimmunity disease etc., the sample of non-clinical sample including food inspection, environment pollution detection, persticide residue detection, biological contamination detection, Biopreparate detection, veterinary science detection, illicit drugs inspection etc.
The utlity model has following beneficial effect:
(1) can Quantitative detection sample component.On examination bar card described in the utility model, storage medium 11 is installed, this storage medium 11 stores the detection information such as checking matter typical curve or coefficient parameter.When testing sample completes on bar after chromatography reaction in examination, by have the detection that tries bar 2 in the instrument collection examination bar card of signal testing function with 6 characteristic signals and in conjunction with this instrument from storage medium 11 read simultaneously the checking matter typical curve that comes or coefficient parameter fast (in a few minutes) quantitatively obtain sample component concentration.
(2) the examination bar 2 in examination bar card described in the utility model, in the time that employing is quantum dot-labeled, can be realized sample polycomponent simultaneously and quick and precisely quantitatively detect.Quantum dot (Quantum Dots, be called for short QDs) be the good spectral signature of a kind of tool of the development nineties in 20th century and the semiconductor nanocrystal of photochemical stability, there is fluorescence radiation efficiency high, exciting line wide ranges, spectral line of emission narrow range, fluorescence lifetime is long, and Stokes displacement is large, particle diameter and biomolecule are close, can multifunction after finishing etc. feature.The quantum dot of different-grain diameter, kind and structure can produce different characteristic wavelength and continue fluorescence peak spectrum, and the characteristic wavelength fluorescence peak spectrum that quantum dot potpourri produces is not overlapping.Adopt different quantum dots mark checking matter respective reaction molecule respectively, its potpourri is coated on the examination bar of examination bar card described in the utility model and reacts with testing sample, try bar specific fluorescent signal by mensuration, quantitative sample polycomponent concentration quick and precisely just in a few minutes.Existing examination bar technology can only qualitative detection sample, can not realize sample and quantitatively detect, and more can not realize sample polycomponent and quantitatively detect.
(3) in described examination bar card, reagent and material do not relate to active inactivation, can preserve for a long time in room temperature.
Accompanying drawing explanation
Figure l: the plan structure figure (showing detection line of examination strip adoption in it) of examination bar card preferred version one described in the utility model
Fig. 2: the side-looking structural drawing of examination bar in the cartridge of examination bar card preferred version one described in the utility model (showing detection line of examination strip adoption)
Fig. 3: the plan structure figure (showing many detection lines of examination strip adoption in it) of examination bar card preferred version one described in the utility model
Fig. 4: the side-looking structural drawing of examination bar in the cartridge of examination bar card preferred version one described in the utility model (showing many detection lines of examination strip adoption)
Fig. 5: the plan structure figure (showing detection line of examination strip adoption in it) of another preferred version of examination bar card described in the utility model
Fig. 6: the side-looking structural drawing of examination bar in the cartridge of another preferred version of examination bar card described in the utility model (showing detection line of examination strip adoption)
Fig. 7: the plan structure figure (showing many detection lines of examination strip adoption in it) of another preferred version of examination bar card described in the utility model
Fig. 8: the side-looking structural drawing of examination bar in the cartridge of another preferred version of examination bar card described in the utility model (showing many detection lines of examination strip adoption)
Sequence number is expressed as follows:
1, end liner, 2, examination bar, 3, cartridge, 4, sample pad, 5, label pad, 6, detect band, 7, analyzing film, 8, adsorptive pads, 9, well, 10, detection window, 11, storage medium, 12, examination bar reaction end indicating label, 13, view window.
Embodiment
Embodiment and accompanying drawing thereof are only in order to further illustrate the utility model below, and those skilled in the art should not limit protection domain of the present utility model with this.
embodiment mono-
Fig. 1-4 explanation embodiment mono-.Embodiment mono-is one of examination bar card preferred version described in the utility model.
In Fig. 1-4, the described examination bar card of described preferred version comprises the examination bar 2 of cartridge 3 and Qi Nei.Described examination bar 2 comprises that overlap joint is fixed on sample pad 4, label pad 5, analyzing film 7, the adsorptive pads 8 on end liner 1 in turn.Analyzing film 7 has to detect is with 6.The upper box face of cartridge 3 is having well 9 corresponding to examination bar sample pad 4 positions.The upper box face of cartridge 3 is having detection window 10 corresponding to examination bar analyzing film 7 positions.One storage medium 11 is installed in cartridge 3.
The a certain target checking matter that the label pad 5 of described examination bar 2 is coated with single labelled substance markers detects relevant single special molecular, or: the each target checking matter that is coated with different label correspondence markings detects the potpourri of relevant special molecular.
The detection of described examination bar 2 is with 6 can be one (shown in Fig. 1 and Fig. 2), can be also many (shown in Fig. 3 and Fig. 4).Detection is coated with a certain target checking matter with 6 and detects another relevant special molecular, or: the potpourri that is coated with another special molecular that each target checking matter detection is relevant.
The checking matter typical curve that described storage medium 11 stores has various ways available, its include but not limited to checking matter standard items series concentration with
a detect bandbetween corresponding relation curve.Described
a detect bandbe defined as the detection band signal intensity that checking matter standard items series concentration records.
The label pad 5 of described examination bar 2 is glass fibre membrane; The analyzing film 7 of described examination bar 2 is nitrocellulose filter, nylon membrane or cellulose nitrate/cellulose acetate hybrid films; The end liner 1 of described examination bar 2 is polyester or plastic plate; Described cartridge 3 is that polyester, plastics, rigid paper material or other materials are made.
Described examination bar 2 is any examination bar, and it includes but not limited to quanta dot mark test bar, colloid gold label examination bar, colloidal selenium marked examination bar, up-converting phosphor substance markers examination bar, nano rare earth fluorescence complex mark test bar, nano magnetic particle mark test bar, time resolution chromatography examination bar, chemiluminescence examination bar.
When described examination bar card is used for sample detection, fluid sample is applied in the well 9 of examination bar card, complete after reaction until examination bar 2 in it, the detection that is gathered examination bar 2 in examination bar card by the instrument (as reading bar instrument, fluorescence detector, magnetic signal detector etc.) with signal testing function is read the checking matter typical curve that comes or coefficient parameter simultaneously and is calculated and obtain sample single component or polycomponent concentration from examination bar card storage medium 11 with 6 characteristic signals and in conjunction with this instrument.
The sample to be checked of described examination bar card can be from clinical or non-clinical blood, body fluid, urine, saliva, genital secretion or other liquid samples or thick sample, wherein, the sample of clinical sample including infectious disease, hormone, cardiovascular disease, tumour, cancer, diabetes, autoimmunity disease etc., the sample of non-clinical sample including food inspection, environment pollution detection, persticide residue detection, biological contamination detection, Biopreparate detection, veterinary science detection, illicit drugs inspection etc.
embodiment bis-
Fig. 5-8 explanation embodiment bis-.Embodiment bis-is another preferred version of examination bar card described in the utility model.
In Fig. 5-8, the described examination bar card of described preferred version comprises the examination bar 2 of cartridge 3 and Qi Nei.Described examination bar 2 comprises that overlap joint is fixed on sample pad 4, label pad 5, analyzing film 7, adsorptive pads 8, the examination bar reaction end indicating label 12 on end liner 1 in turn.Analyzing film 7 has to detect is with 6.The upper box face of cartridge 3 is having well 9 corresponding to examination bar sample pad 4 positions.The upper box face of cartridge 3 is having detection window 10 corresponding to examination bar analyzing film 7 positions.The upper box face of cartridge 3 is having view window 13 corresponding to examination bar reaction end indicating label 12 positions.One storage medium 11 is installed in cartridge 3.
The a certain target checking matter that the label pad 5 of described examination bar 2 is coated with single labelled substance markers detects relevant single special molecular, or: the each target checking matter that is coated with different label correspondence markings detects the potpourri of relevant special molecular.
The detection of described examination bar 2 is with 6 can be one (shown in Fig. 5 and Fig. 6), can be also many (shown in Fig. 7 and Fig. 8).Detection is coated with a certain target checking matter with 6 and detects another relevant special molecular, or: the potpourri that is coated with another special molecular that each target checking matter detection is relevant.
Described examination bar reaction end indicating label 12 includes but not limited to that color change interval is the pH test paper of 5-9.When sample detection, the examination bar reaction end indicating label 12 of examination on bar can develop the color according to the pH condition of examination bar reaction, is with 6 to point out examination bar reactant whether fully to ooze to move past to detect, and whether the reaction of prompting examination bar is abundant, and whether its testing result is effective.
The checking matter typical curve that described storage medium 11 stores has various ways available, its include but not limited to checking matter standard items series concentration with
a detect bandbetween corresponding relation curve.Described
a detect bandbe defined as the detection band signal intensity that checking matter standard items series concentration records.
The label pad 5 of described examination bar 2 is glass fibre membrane; The analyzing film 7 of described examination bar 2 is nitrocellulose filter, nylon membrane or cellulose nitrate/cellulose acetate hybrid films; The end liner 1 of described examination bar 2 is polyester or plastic plate; Described cartridge 3 is that polyester, plastics, rigid paper material or other materials are made.
Described examination bar 2 is any examination bar, and it includes but not limited to quanta dot mark test bar, colloid gold label examination bar, colloidal selenium marked examination bar, up-converting phosphor substance markers examination bar, nano rare earth fluorescence complex mark test bar, nano magnetic particle mark test bar, time resolution chromatography examination bar, chemiluminescence examination bar.
When described examination bar card is used for sample detection, fluid sample is applied in the well 9 of examination bar card, examination bar reaction end indicating label 12 indication examination bars 2 until examination bar 2 in it complete after reaction, and the detection that is gathered examination bar 2 in examination bar card by the instrument (as reading bar instrument, fluorescence detector, magnetic signal detector etc.) with signal testing function is read the checking matter typical curve that comes or coefficient parameter simultaneously and calculated and obtain sample single component or polycomponent concentration from examination bar card storage medium 11 with 6 characteristic signals and in conjunction with this instrument.
The sample to be checked of described examination bar card can be from clinical or non-clinical blood, body fluid, urine, saliva, genital secretion or other liquid samples or thick sample, wherein, the sample of clinical sample including infectious disease, hormone, cardiovascular disease, tumour, cancer, diabetes, autoimmunity disease etc., the sample of non-clinical sample including food inspection, environment pollution detection, persticide residue detection, biological contamination detection, Biopreparate detection, veterinary science detection, illicit drugs inspection etc.
It is pointed out that examination bar card described in the utility model can also have other to improve, as upper outside except being arranged on the cartridge 3 of examination bar card in the storage medium 11 that stores the detections information such as checking matter typical curve, also can be directly installed on that examination bar card is interior to be tried on bar 2; Based on the utility model same principle, the examination bar in cartridge 3 also can be expanded and replace with biochip (comprising antigen-antibody chip, protein chip, nucleic acid chip, micro-fluidic chip) etc.Therefore, every to any other technical scheme that is equal to replacement or equivalent transformation formation of examination bar card employing described in the utility model, all drop in the protection domain of the utility model claim.
Claims (1)
1. an examination bar card, comprise cartridge (3) and the examination bar (2) in it, examination bar (2) comprises that overlap joint is fixed on the sample pad (4) on end liner (1) in turn, label pad (5), analyzing film (7), adsorptive pads (8), analyzing film (7) has the band of detection (6), detecting band (6) is one or more, the upper box face of cartridge (3) is having well (9) corresponding to examination bar sample pad (4) position, the upper box face of cartridge (3) is having detection window (10) corresponding to examination bar analyzing film (7) position, it is characterized in that: a storage medium (11) is also installed in described cartridge (3).
2. examination bar card according to claim 1, is characterized in that:
The a certain target checking matter that the label pad (5) of described examination bar (2) is coated with single labelled substance markers detects relevant single special molecular, or: the each target checking matter that is coated with different label correspondence markings detects the potpourri of relevant special molecular;
The detection band (6) of described examination bar (2) is coated with a certain target checking matter and detects another relevant special molecular, or: the potpourri that is coated with another special molecular that each target checking matter detection is relevant.
3. examination bar card according to claim 1, is characterized in that: the storage medium (11) in described cartridge (3) comprises RFID label, IC chip, magnetic code or bar code.
4. examination bar card according to claim 1, it is characterized in that: described storage medium (11) stores with batch examination bar (2) the checking matter typical curve that quantitatively sample concentration is used or coefficient parameter, examination bar lot number, tries bar effect phase, storage medium password, clinical indices reference value, Shi Tiao production firm information, and can read in measurand identity information, tester's information, sample title, sample number into spectrum, detection date, testing result information.
5. examination bar card according to claim 4, is characterized in that: the checking matter typical curve that described storage medium (11) stores has various ways available, it comprise checking matter standard items series concentration with
a detect bandbetween corresponding relation curve; Described
a detect bandbe defined as the detection band signal intensity that checking matter standard items series concentration records.
6. examination bar card according to claim 1, is characterized in that:
The label pad (5) of described examination bar (2) is glass fibre membrane, and the analyzing film (7) of described examination bar (2) is nitrocellulose filter, nylon membrane or cellulose nitrate/cellulose acetate hybrid films;
The end liner (1) of described examination bar (2) is polyester or plastic plate;
Described cartridge (3) is that polyester, plastics or rigid paper material are made.
7. examination bar card according to claim 1, it is characterized in that: wherein said examination bar (2) is any examination bar, it comprises quanta dot mark test bar, colloid gold label examination bar, colloidal selenium marked examination bar, up-converting phosphor substance markers examination bar, nano rare earth fluorescence complex mark test bar, nano magnetic particle mark test bar, time resolution chromatography examination bar, chemiluminescence examination bar.
8, examination bar card according to claim 1, it is characterized in that: when sample detection, the instrument collection with signal testing function tries examination bar (2) in bar card and detects the characteristic signal of band (6) the checking matter typical curve simultaneously reading from storage medium (11) in conjunction with this instrument or coefficient parameter and calculate acquisition sample single component or polycomponent concentration.
9. an examination bar card as claimed in claim 1, is characterized in that: the adsorptive pads (8) of wherein said examination bar (2) is also overlapped with an examination bar reaction end indicating label (12) afterwards; This examination bar reaction end indicating label (12) corresponding position of its cartridge (3) has view window (13).
10. examination bar card according to claim 9, is characterized in that, described examination bar reaction end indicating label (12) comprises that color change interval is the pH test paper of 5-9.
11. examination bar cards according to claim 9, is characterized in that:
The a certain target checking matter that the label pad (5) of described examination bar (2) is coated with single labelled substance markers detects relevant single special molecular, or: the each target checking matter that is coated with different label correspondence markings detects the potpourri of relevant special molecular;
The detection band (6) of described examination bar (2) is coated with a certain target checking matter and detects another relevant special molecular, or: the potpourri that is coated with another special molecular that each target checking matter detection is relevant.
12. examination bar cards according to claim 9, is characterized in that: the storage medium (11) in described cartridge (3) comprises RFID label, IC chip, magnetic code or bar code.
13. examination bar cards according to claim 9, it is characterized in that: described storage medium (11) stores with batch examination bar (2) the checking matter typical curve that quantitatively sample concentration is used or coefficient parameter, examination bar lot number, tries bar effect phase, storage medium password, clinical indices reference value, Shi Tiao production firm information, and can read in measurand identity information, tester's information, sample title, sample number into spectrum, detection date, testing result information.
14. examination bar cards according to claim 13, is characterized in that: the checking matter typical curve that described storage medium (11) stores has various ways available, it comprise checking matter standard items series concentration with
a detect bandbetween corresponding relation curve; Described
a detect bandbe defined as the detection band signal intensity that checking matter standard items series concentration records.
15. examination bar cards according to claim 9, is characterized in that:
The label pad (5) of described examination bar (2) is glass fibre membrane, and the analyzing film (7) of described examination bar (2) is nitrocellulose filter, nylon membrane or cellulose nitrate/cellulose acetate hybrid films;
The end liner (1) of described examination bar (2) is polyester or plastic plate;
Described cartridge (3) is that polyester, plastics or rigid paper material are made.
16. examination bar cards according to claim 9, it is characterized in that: wherein said examination bar (2) is any examination bar, it comprises quanta dot mark test bar, colloid gold label examination bar, colloidal selenium marked examination bar, up-converting phosphor substance markers examination bar, nano rare earth fluorescence complex mark test bar, nano magnetic particle mark test bar, time resolution chromatography examination bar, chemiluminescence examination bar.
17. examination bar cards according to claim 9, it is characterized in that: when sample detection, try bar reaction end indicating label (12) and indicate sample on examination bar (2), to complete after the reaction of examination bar, tried to try in bar card the characteristic signal of bar (2) detection band (6) the checking matter typical curve simultaneously reading from storage medium (11) in conjunction with this instrument or coefficient parameter and calculate to obtain sample single component or polycomponent concentration by the instrument collection with signal testing function.
Priority Applications (1)
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CN201320722060.5U CN203606364U (en) | 2013-11-16 | 2013-11-16 | Test strip card |
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CN201320722060.5U CN203606364U (en) | 2013-11-16 | 2013-11-16 | Test strip card |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103645312A (en) * | 2013-11-16 | 2014-03-19 | 成都领御生物技术有限公司 | Test strip card |
WO2015070699A1 (en) * | 2013-11-12 | 2015-05-21 | 成都领御生物技术有限公司 | Quantum dot-labeled test strip card |
WO2015070704A1 (en) * | 2013-11-13 | 2015-05-21 | 成都领御生物技术有限公司 | Test bar card |
WO2015070700A1 (en) * | 2013-11-12 | 2015-05-21 | 成都领御生物技术有限公司 | Quantum dot-labeled test strip card |
CN105606808A (en) * | 2016-03-30 | 2016-05-25 | 珠海华澳生物科技有限公司 | Group A/B streptococcus colloidal gold immunochromatograohic assay detection device and detection method thereof |
-
2013
- 2013-11-16 CN CN201320722060.5U patent/CN203606364U/en not_active Expired - Lifetime
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015070699A1 (en) * | 2013-11-12 | 2015-05-21 | 成都领御生物技术有限公司 | Quantum dot-labeled test strip card |
WO2015070700A1 (en) * | 2013-11-12 | 2015-05-21 | 成都领御生物技术有限公司 | Quantum dot-labeled test strip card |
WO2015070704A1 (en) * | 2013-11-13 | 2015-05-21 | 成都领御生物技术有限公司 | Test bar card |
CN103645312A (en) * | 2013-11-16 | 2014-03-19 | 成都领御生物技术有限公司 | Test strip card |
WO2015070749A1 (en) * | 2013-11-16 | 2015-05-21 | 成都领御生物技术有限公司 | Test strip card |
CN105606808A (en) * | 2016-03-30 | 2016-05-25 | 珠海华澳生物科技有限公司 | Group A/B streptococcus colloidal gold immunochromatograohic assay detection device and detection method thereof |
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