CN201750916U - Three-layer soft capsule dropper head device - Google Patents
Three-layer soft capsule dropper head device Download PDFInfo
- Publication number
- CN201750916U CN201750916U CN2010202244281U CN201020224428U CN201750916U CN 201750916 U CN201750916 U CN 201750916U CN 2010202244281 U CN2010202244281 U CN 2010202244281U CN 201020224428 U CN201020224428 U CN 201020224428U CN 201750916 U CN201750916 U CN 201750916U
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- Prior art keywords
- soft capsule
- diameter
- outlet
- inlet
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- Expired - Fee Related
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- 239000007901 soft capsule Substances 0.000 title claims abstract description 37
- 230000007704 transition Effects 0.000 claims abstract description 17
- 239000012530 fluid Substances 0.000 claims abstract description 12
- 239000002775 capsule Substances 0.000 abstract description 14
- 238000013461 design Methods 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 abstract description 2
- 239000010410 layer Substances 0.000 description 36
- 239000003292 glue Substances 0.000 description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 229920000159 gelatin Polymers 0.000 description 6
- 235000019322 gelatine Nutrition 0.000 description 6
- 238000002347 injection Methods 0.000 description 6
- 239000007924 injection Substances 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 108010010803 Gelatin Proteins 0.000 description 5
- 239000008273 gelatin Substances 0.000 description 5
- 235000011852 gelatine desserts Nutrition 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 4
- 239000003921 oil Substances 0.000 description 4
- 239000002356 single layer Substances 0.000 description 4
- 235000010413 sodium alginate Nutrition 0.000 description 4
- 229940005550 sodium alginate Drugs 0.000 description 4
- 239000000661 sodium alginate Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000001828 Gelatine Substances 0.000 description 1
- 206010019133 Hangover Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000000701 coagulant Substances 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000026676 system process Effects 0.000 description 1
- 238000004078 waterproofing Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
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Abstract
The utility model discloses a three-layer soft capsule dropper head device, belonging to the technical field of instrument and equipment. The three-layer soft capsule dropper head device consists of the top, the middle and the lower of an arc fluid flow passage which is arranged in the device, the middle of the arc fluid flow passage is fixedly connected with the bottom of an upper connecting piece into a whole body, the top of the arc fluid flow passage is connected with the top of the upper connecting piece into a whole body by a threaded structure, and the middle and the lower of the arc fluid flow passage are connected with a middle connecting piece into a whole body by a threaded structure; the outer-layer inlet of the fluid flow passage is arranged at the upper end of the center of the top, and the outer-layer outlet is arranged at the lowest end of the lower part; the middle-layer is arranged on the upper connecting piece, and the middle-layer outlet is arranged above a transition region; and the inner-layer inlet is arranged on the middle connecting piece, and the inner-layer outlet is arranged at the lower end of a lower cone. The three-layer soft capsule dropper head device is reasonable in design, simple in structure, and good in use effect, can meet the requirement of different tests, can product the capsules with different structures in a dropping way, and has the advantages of being convenient to clean.
Description
Technical field
This utility model belongs to the instrument and equipment technical field, is specifically related to a kind of capsular dripper device with multiple structure that is used to make.
Background technology
In the prior art, soft capsule is the pharmaceutical preparation novel form that a kind of new development is got up.Owing in pharmaceutical preparation, having sheet, advantage that injection did not have to be widely used, can make the different cultivars of for oral administration or external as required, generally by dropping preparation method and pressing preparation.The main dropping preparation method that adopts in experiment, in the research work process, find, the soft capsule shell of traditional dropping preparation method preparation is a monolayer glue shell, reaching particular requirement need be by revising the prescription of soft capsule rubber, and the prescription that obtains this soft capsule rubber sometimes and be not easy, even we can say and be difficult to reach.The water proofing property of for example traditional soft capsule shell itself is exactly a problem, and mainly one procedure---coating solves by adding now.Because special fragility and the unstability of our required soft capsule, it is the comparison difficulty that the method by coating solves waterproof.
The utility model content
Above-mentioned deficiency at prior art, problem to be solved in the utility model provides a kind of three layers of soft capsule dripper device, this device can drip the soft capsule of specific (special) requirements such as making certain waterproof, protection against the tide, also can wrap up wetting agent by double-deck lipophile shell.Satisfy the primary demand of multiple special soft capsule prescription, provide basis and convenient for studying double-deck capsule shells soft capsule later on.
The technical solution of the utility model is: three layers of soft capsule dripper device are made up of top, middle part and bottom three parts of the fluid passage that is provided with the band radian in it, the middle part is connected to one with last brace bottom or is connected by helicitic texture, the top connects as one by helicitic texture and last brace top, and middle part and bottom connect as one by helicitic texture and middle brace; The skin inlet of described fluid passage is arranged on the center of top upper end, and outer outlet is arranged on the bottom bottom; The middle level inlet is arranged on the brace, and the middle level outlet is arranged on the transition region; On the brace, the internal layer outlet was arranged on the lower end of lower cone during the internal layer inlet was arranged on.Described center of top is provided with the central authorities that upper cone, middle part central authorities be provided with middle cone, bottom and is provided with lower cone.Also be provided with buckle syndeton or socket connection structure between described middle part and bottom and the middle brace.The diameter of described internal layer outlet is 0.2-5mm; The diameter of middle level outlet is 4-10mm; The diameter of outer outlet is 6-15mm.The diameter of best internal layer outlet is 1-3mm; The diameter of best middle level outlet is 5-7mm; The diameter of best skin outlet is 7-10mm.The diameter of described outer inlet, middle level inlet, internal layer inlet is 1-10mm.The diameter of best skin inlet, middle level inlet, internal layer inlet is 2.5-6mm.The diameter of described transition region is than the big 0.5-10mm of diameter of middle level outlet.The diameter of best transition region is than the big 1.5-6mm of diameter of middle level outlet.
This utility model is reasonable in design, and structure is simple and direct, and result of use is good, can satisfy different test demands, drips the capsule make various different structures, and this device also has and cleans advantage easily.
Description of drawings
Accompanying drawing 1 is this utility model one embodiment sectional structure sketch map;
Accompanying drawing 2 is middle brace central plane structural representations of accompanying drawing 1.
Accompanying drawing acceptance of the bid keep the score state as follows: the outer inlet of 1-; The 2-upper cone; The last brace of 3-; 4-middle level passage; 5-internal layer passage; Brace among the 6-; The 7-bottom; The outlet of 8-middle level; The outer outlet of 9-; The 10-top; 11-middle level inlet; The 12-outer layer channel; Cone among the 13-; The 14-middle part; 15-internal layer inlet; The 16-lower cone; The outlet of 17-internal layer; The 18-transition region; 19-buckle syndeton or socket connection structure.
The specific embodiment
Below in conjunction with accompanying drawing detailed description is done into-gone on foot to the specific embodiment of the present utility model.Shown in accompanying drawing 1,2, this utility model is provided with the three-layer fluid passage, when using this equipment, can drip and make double-layer soft capsule, can reach the requirement of double shells soft capsule.This dripper device is made up of three layers of passage: i.e. internal layer passage 5, middle level passage 4, outer layer channel 12.Owing to have three layers, in the capsule that this device obtains can be designed to-in-be respectively the general layout of oil-water-oil outward, also can be interior-in-be respectively the general layout of water-oil-water outward, can also be oil-oil-water, oil-water-water, water-oil-wet goods various combination.These can carry out different selections according to required capsular characteristics in the experimentation, reach required requirement of experiment." oil " and " water " described here are meant oleophilic substance and hydrophilic substance.
Dripper device of the present utility model, what outer inlet 1 added is the glue part of soft capsule outermost shell, and what middle level inlet 11 added is soft capsule shell inner layer case glue part, and what internal layer inlet 15 added is capsulated innermost layer glue nuclear part.The size of injection port internal diameter can be carried out different designs according to features such as gelatin viscosities, and the temperature of injection port can be regulated (this is a prior art) by the equipment of instrument liquid storage pipe.Glue nuclear partially liq directly enters by internal layer inlet 15, flows out by internal layer outlet 17.The glue that forms the internal layer soft capsule shell be by in the last brace 3 middle level inlet 11 enter, 14 middle cone 13 is shunted at the middle part, and glue flows down uniformly, brace 6 in flowing to, by aperture wherein, flow to bottom 7 smoothly, glue flows out under the control of internal layer and middle level wall, regulates the flow velocity of middle level glue, can be with the perfect parcel of glue nuclear, ooze by capsule middle level outlet 8, drip in the transition region 18, and then carry out the parcel of outer layer glue softgel shell.
Outer layer glue softgel shell glue enters by skin inlet 1, at first shunt by upper cone 2, liquid can be dispersed in more uniformly first bonding pad of taper, thereby can enter more uniformly in the outer layer channel 12 at middle part 14, certainly the cavity of outer layer channel 12 also has radian, can guarantee that glue can flow to middle brace 6 smoothly uniformly, and then enter bottom 7, radian in the 7 outermost layer cavitys of bottom also designs according to the different viscosities glue, can guarantee that glue can flow out smoothly and can wrap up the monolayer soft capsule that oozes transition region 18 from the middle level.Export the capsule of 9 effusive final double wrapped from skin, can splash into coagulation forming in the capsules settle agent, final drying obtains double-deck capsule shells capsule.
Diameter at the skin inlet 1 at the top 10 of dripper device can be 1-10mm, and preferred 2.5-6mm can certainly be according to the different injection port of particular viscosity design of glue.The diameter of middle level inlet 11 can be 1-10mm, and preferred 2.5-6mm can certainly be according to the different injection port of particular viscosity design of glue.The diameter of internal layer inlet 15 also can 1-10mm, and preferred 2.5-6mm can certainly be according to the different injection port of particular viscosity design of glue.In, in, the outer vent diameter is also very important, the diameter 0.2-5mm of internal layer outlet 17, preferred 1-3mm; The diameter 4-10mm of middle level outlet 8, preferred 5-7mm; The diameter 6-15mm of outer outlet 9, preferred 7-10mm.The diameter of three outlets not only is limited in this scope, sometimes can set according to the concrete viscosity of glue again.
In this top 10, middle part 14, bottom 7, the cross section of the face that each contacts with glue all is circle or arcuate structure (seeing accompanying drawing 2), the size of the taper radian of each area part, design according to the viscosity of glue and the size of actual used water dropper, can certainly not having radian directly is pyramidal structure etc.The size of the thickness of each fluid passage cavity also is that the viscosity according to glue designs, and for example can be 1-15mm, preferred 2.5-8mm etc.Certainly be not confined in this scope.This will carry out adjusting accordingly in proportion or according to a certain percentage according to the concrete size of water dropper.This is the content of prior art, does not give unnecessary details.
At the top 10, in the middle of the middle part 14, bottom 7 two braces are arranged, call brace 3, middle brace 6 (seeing accompanying drawing 2) respectively.The effect of these two braces is that top 10, middle part 14, bottom 7 are connected, top 10, middle part 14, bottom 7 these three parts can partly be done together, also can all separate, can certainly all connect, separate section can connect by modes such as bolt, screw threads.Be threaded and directly first, second and third each several part directly be connected first and second brace by screw thread.Each several part separately is preferred selection, because glue all has certain viscosity, is convenient to clean after dripping the system soft capsule.
Also has a special transition region 18 at this water dropper, after the monolayer capsule oozes, with a special transition region 18 is arranged when the outermost layer capsule shells contacts, the existence of this transition region 18 be in order to prevent that from there is the existence of hangover or adhesion in capsules that middle level outlet 8 oozes, be enclosed with certain influence to outermost.The diameter of transition region 18 exports 8 big than the middle level, the purpose of doing like this is in order to prevent that transition region 18 from adhering to soft capsule.The diameter of transition region 18 is than the big 0.5-10mm of diameter of middle level outlet 8, and preferred 1.5-6mm also can carry out actual adjustment according to the difference of viscosity, drips in the system process transition region 18 and does not run into soft capsule to reach.
Describe below one with the double-deck capsular embodiment of this device preparation: at first dispose three kinds of required solution, for example kernel portion is Oleum Brassicae campestris and 1: 1 mixed liquor of Oleum menthae, and the capsule shells internal layer is a gelatin solution, and skin is the sodium alginate glue.Three kinds of liquid are put in three fluid reservoirs of preprepared, feed in raw material by peristaltic pump, and can the regulator solution flow velocity, three different solution are linked in the three above-mentioned hole water droppers, and oil, gelatin, sodium alginate add respectively by internal layer inlet 15, middle level inlet 12, outer inlet 1 respectively.Oil: gelatin=can ooze monolayer soft capsule at 1: 4.Can be by the speed of splashing into of regulating sodium alginate completely with the gelatine capsule parcel that has oozed in transition region 18.Drop into coagulant then and solidify the soft capsule that is respectively gelatin and sodium alginate that drying obtains double shells.This soft capsule has the characteristic that can change hardness.
Claims (9)
1. three layers of soft capsule dripper device, it is characterized in that: described dripper device is made up of top (10), middle part (14) and bottom (7) three parts of the fluid passage that is provided with the band radian in it, middle part (14) is connected to one with last brace (3) bottom or is connected by helicitic texture, top (10) connects as one by helicitic texture and last brace (3) top, and middle part (14) and bottom (7) connect as one by helicitic texture and middle brace (6); The skin inlet (1) of described fluid passage is arranged on the center of top upper end, and outer outlet (9) is arranged on bottom (7) bottom; Middle level inlet (11) is arranged on the brace (3), and middle level outlet (8) is arranged on the transition region (18); Internal layer inlet (15) is arranged on the middle brace (6), and internal layer outlet (17) is arranged on the lower end of lower cone (16).
2. three layers of soft capsule dripper device according to claim 1 is characterized in that: described top (10) central authorities are provided with the central authorities that upper cone (2), middle part (14) central authorities be provided with middle cone (13), bottom (7) and are provided with lower cone (16).
3. three layers of soft capsule dripper device according to claim 1 is characterized in that: also be provided with buckle syndeton or socket connection structure (19) between described middle part (14) and bottom (7) and the middle brace (6).
4. three layers of soft capsule dripper device according to claim 1 is characterized in that: the diameter of described internal layer outlet (17) is 0.2-5mm; The diameter of middle level outlet (8) is 4-10mm; The diameter of outer outlet (9) is 6-15mm.
5. three layers of soft capsule dripper device according to claim 4 is characterized in that: the diameter of described internal layer outlet (17) is 1-3mm; The diameter of middle level outlet (8) is 5-7mm; The diameter of outer outlet (9) is 7-10mm.
6. three layers of soft capsule dripper device according to claim 1 is characterized in that: the diameter of described outer inlet (1), middle level inlet (11), internal layer inlet (15) is 1-10mm.
7. three layers of soft capsule dripper device according to claim 6 is characterized in that: the diameter of described outer inlet (1), middle level inlet (11), internal layer inlet (15) is 2.5-6mm.
8. three layers of soft capsule dripper device according to claim 1 is characterized in that: the diameter of described transition region (18) is than the big 0.5-10mm of diameter of middle level outlet (8).
9. three layers of soft capsule dripper device according to claim 8 is characterized in that: the diameter of described transition region (18) is than the big 1.5-6mm of diameter of middle level outlet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010202244281U CN201750916U (en) | 2010-06-07 | 2010-06-07 | Three-layer soft capsule dropper head device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010202244281U CN201750916U (en) | 2010-06-07 | 2010-06-07 | Three-layer soft capsule dropper head device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201750916U true CN201750916U (en) | 2011-02-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010202244281U Expired - Fee Related CN201750916U (en) | 2010-06-07 | 2010-06-07 | Three-layer soft capsule dropper head device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201750916U (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102652854A (en) * | 2012-05-03 | 2012-09-05 | 瞿祥鹏 | Dripper |
| CN104905967A (en) * | 2015-05-23 | 2015-09-16 | 浙江益立胶囊股份有限公司 | Production mold for double-layer enteric hollow capsule |
| CN105410995A (en) * | 2015-12-11 | 2016-03-23 | 贵州中烟工业有限责任公司 | Dripper device for tobacco-use capsule |
| CN105410996A (en) * | 2015-12-11 | 2016-03-23 | 贵州中烟工业有限责任公司 | Dripper device with temperature control function for tobacco-use capsule |
| CN105616164A (en) * | 2016-03-30 | 2016-06-01 | 深圳万和制药有限公司 | Multi-layer dripping pill device, component thereof and preparation process of multi-layer pill dripping device |
| CN106924046A (en) * | 2017-04-24 | 2017-07-07 | 中国科学技术大学 | Medicine-carrying capsule prepares shower nozzle and medicine-carrying capsule preparation facilities |
| CN107361392A (en) * | 2017-07-26 | 2017-11-21 | 云南芯韵科技开发有限公司 | A kind of three layers containing capsule with diuresis promoting function and preparation method thereof |
| CN107997968A (en) * | 2017-11-28 | 2018-05-08 | 宁波明佳汽车内饰有限公司 | A kind of soft capsule manufacturing process |
| CN109875117A (en) * | 2017-12-06 | 2019-06-14 | 贵州中烟工业有限责任公司 | A kind of quick-fried pearl two-phase flow dripper device of cigarette and the quick-fried pearl process equipment of cigarette |
| CN109875115A (en) * | 2017-12-06 | 2019-06-14 | 贵州中烟工业有限责任公司 | A kind of quick-fried pearl two-phase flow dripper device of cigarette and the quick-fried pearl process equipment of cigarette |
| CN111821925A (en) * | 2020-07-23 | 2020-10-27 | 重庆东圣精工科技股份有限公司 | Microcapsule preparation facilities |
-
2010
- 2010-06-07 CN CN2010202244281U patent/CN201750916U/en not_active Expired - Fee Related
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102652854A (en) * | 2012-05-03 | 2012-09-05 | 瞿祥鹏 | Dripper |
| CN104905967B (en) * | 2015-05-23 | 2019-04-16 | 浙江益立胶囊股份有限公司 | Production mould for the double-deck enteric hollow capsule |
| CN104905967A (en) * | 2015-05-23 | 2015-09-16 | 浙江益立胶囊股份有限公司 | Production mold for double-layer enteric hollow capsule |
| CN105410995A (en) * | 2015-12-11 | 2016-03-23 | 贵州中烟工业有限责任公司 | Dripper device for tobacco-use capsule |
| CN105410996A (en) * | 2015-12-11 | 2016-03-23 | 贵州中烟工业有限责任公司 | Dripper device with temperature control function for tobacco-use capsule |
| CN105410996B (en) * | 2015-12-11 | 2023-11-24 | 贵州中烟工业有限责任公司 | Take control by temperature change's capsule water dropper device for cigarette |
| CN105410995B (en) * | 2015-12-11 | 2023-11-24 | 贵州中烟工业有限责任公司 | Capsule dripper device for cigarettes |
| CN105616164A (en) * | 2016-03-30 | 2016-06-01 | 深圳万和制药有限公司 | Multi-layer dripping pill device, component thereof and preparation process of multi-layer pill dripping device |
| CN105616164B (en) * | 2016-03-30 | 2019-05-31 | 深圳万和制药有限公司 | The preparation process of multilayer pill equipment and its component and multilayer pill |
| CN106924046A (en) * | 2017-04-24 | 2017-07-07 | 中国科学技术大学 | Medicine-carrying capsule prepares shower nozzle and medicine-carrying capsule preparation facilities |
| CN107361392B (en) * | 2017-07-26 | 2019-10-25 | 云南芯韵科技开发有限公司 | A kind of three layers contain capsule with diuresis promoting function and preparation method thereof |
| CN107361392A (en) * | 2017-07-26 | 2017-11-21 | 云南芯韵科技开发有限公司 | A kind of three layers containing capsule with diuresis promoting function and preparation method thereof |
| CN107997968A (en) * | 2017-11-28 | 2018-05-08 | 宁波明佳汽车内饰有限公司 | A kind of soft capsule manufacturing process |
| CN109875117A (en) * | 2017-12-06 | 2019-06-14 | 贵州中烟工业有限责任公司 | A kind of quick-fried pearl two-phase flow dripper device of cigarette and the quick-fried pearl process equipment of cigarette |
| CN109875115A (en) * | 2017-12-06 | 2019-06-14 | 贵州中烟工业有限责任公司 | A kind of quick-fried pearl two-phase flow dripper device of cigarette and the quick-fried pearl process equipment of cigarette |
| CN109875115B (en) * | 2017-12-06 | 2022-02-18 | 贵州中烟工业有限责任公司 | Bead-blasting two-phase flow water dropper device for cigarettes and bead-blasting processing equipment for cigarettes |
| CN109875117B (en) * | 2017-12-06 | 2022-02-18 | 贵州中烟工业有限责任公司 | Bead-blasting two-phase flow water dropper device for cigarettes and bead-blasting processing equipment for cigarettes |
| CN111821925A (en) * | 2020-07-23 | 2020-10-27 | 重庆东圣精工科技股份有限公司 | Microcapsule preparation facilities |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110223 Termination date: 20160607 |