CN201653970U - Electrochemical biological sensing test paper - Google Patents
Electrochemical biological sensing test paper Download PDFInfo
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- CN201653970U CN201653970U CN2010201398827U CN201020139882U CN201653970U CN 201653970 U CN201653970 U CN 201653970U CN 2010201398827 U CN2010201398827 U CN 2010201398827U CN 201020139882 U CN201020139882 U CN 201020139882U CN 201653970 U CN201653970 U CN 201653970U
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Abstract
The utility model discloses electrochemical biological sensing test paper which comprises a substrate that can be divided into a front surface and a back surface, a conductive layer arranged on the front surface of the substrate, a parameter identification component arranged at one end of the back surface of the substrate, an upper clapboard covered on the conductive layer, and a reaction area contacted with the conductive layer and used for reacting. When the electrochemical biologic sensing test paper is connected with a matched biological sensor device, the device can automatically select a group of calibration parameter values corresponding to the batch of test paper by identifying the parameter identification component, so as to further omit a parameter calibration step conducted by a user, simplify the overall measurement procedures, and avoid inaccurate test results caused by careless omission or operation mistake of the user.
Description
Technical field
The utility model relates to a kind of electrochemical biological sensing test paper, relates in particular to a kind ofly to be provided with a parameter identification element and can to remove the electrochemical biological sensing test paper that the user carries out the parameter correction step from substrate back one end.
Background technology
Because the progress of science and technology, the direction of test is at home moved towards in many tests that must just can detect in hospital of past now mostly.Have on the market at present and manyly be discardable after using once and be used at home biological sensing test paper (biosensor strip) from line operate, being fit to layman and nursing at home uses, the situation that does not have pollution takes place, and cooperate suitable biosensor arrangement (biosensing device), can measure correct measurement numerical value.
With the blood sugar test technology is example, operates advantage convenient and timely check owing to have, and blood glucose meter has become the bedside that generally uses in clinical and the home care operation in recent years and detected (Point of care test, POCT) one of medical equipment.According to the statistical report explanation of TaiWan, China diabetes association, the analysis principle of present commercially available blood glucose meter mainly is to utilize galvanochemistry (Amperometric electrochemistry) principle to test; After the enzyme on glucose in the blood and the electrochemical biological sensing test paper produces electrochemical reaction,, the electric current variation is converted to blood sugar concentration numerical value by blood glucose meter by disengaging of medium electronics.
Known electrochemical biological sensing test paper has a substrate, one conductive layer, one reaction zone and a upper spacer, on this substrate, form conductive layer, this conductive layer comprises two and separates and not contacted mutually anode part and cathode portion, the part covers one deck electric insulation layer and exposes the partially conductive layer on this conductive layer, part one end that this conductive layer anode and negative electrode expose forms working electrode and reference electrode, the other end then can be connected with biosensor arrangement, and on this working electrode and reference electrode, cover a reaction zone, this reaction zone is looked different principle and is made, and covers a upper spacer on reaction zone.After sample sucks, sample promptly can react with the reaction zone material and produce electrochemical change, and conduct to the negative contact and the positive contact of the conductive layer other end by working electrode and reference electrode, by being connected with biosensor arrangement and received signal, become testing concentration to be shown on the display conversion of signals through calculating.
Yet, because the electrochemical biological sensing test paper is all made in the mode of producing (batch production) in batches at present, therefore the every change in the manufacture process will be because of causing the otherness between every batch of test paper, the enzyme amount in the volume of working electrode and reference electrode, reaction zone etc. for example all can influence to detect and causes measurement result inaccurate.Therefore before the blood glucose meter special test paper dispatched from the factory, manufacturer can set one group of specific correction parameter values according to the product of each lot number, to confirm the consistance of check analysis value.The corrective action of blood glucose meter intrinsic parameter is promptly to confirm that test paper can be because of not making the lot number difference, and different analysis results is arranged.
The bearing calibration of present commercially available blood glucose meter intrinsic parameter mainly contains chip setting method, test paper numbering checking method etc.With the chip setting method is example, every box blood sugar test paper is before bringing into use, all must be earlier proofread and correct parameter in the blood glucose meter with the chip of built-in, yet sufferer or the family members that implement to measure but forget this corrective action often, the blood glucose value that causes measuring very accurately and is not known.A kind of biosensor arrangement that utilizes the parameter correction test paper to carry out parameter correction that U.S.'s patent of invention publication number is provided for No. 20030204313, its parameter correction mode are just approximate therewith.And U.S.'s patent of invention the 7th, 514, No. 040, be about a kind of can built-in parameter password also can plug-in parameter password intelligent biosensor arrangement, it is in the built-in array correction parameter values of biosensor arrangement, the user must select the parameter value that matches with this batch test paper earlier before measuring, its parameter correction mode belongs to test paper numbering checking method.
As previously mentioned, no matter blood glucose meter is used existing any parameter correction mode, all need additionally to increase user's operation steps, cause loaded down with trivial details on the trace routine, and the user is in case careless omission or this aligning step of correct execution not, then can't obtain correct testing result, not only lose time and resource, more life and the health control to sufferer causes negative effect.Defend teaching meeting investigation statistics in 2006 according to the TaiWan, China diabetes and show that 32.9% sufferer mistake is used blood glucose meter, forget correction before comprising use, cause measuring inaccurate, influence glycemic control.Aforementioned disadvantages is seen some from this to the inconvenience that the user causes.Therefore, how simplifying even save the aligning step of user before measurement, but still can keep the accuracy of measurement result, is to demand improvements urgently for various equivalent modifications.
In addition, can correctly use the electrochemical biological sensing test paper in order to ensure the user, often have selectivity between different test paper and biosensor arrangement that it matches, promptly this test paper only can correct execution measure action under the situation of the biosensor arrangement that insertion matches.And the designer and manufacturer of electrochemical biological sensing test paper often must be according to various objectives, different determinands, different clients and different terminals user produce the test paper of the different biosensor arrangements of multiple cooperation, to meet the diversity demand in market, therefore, be full of different producer's sign of all kinds at present on the market, the electrochemical biological sensing test paper and the biosensor arrangement of design and purpose, rise along with the customized service of medical treatment, we can predict, and the kind of electrochemical biological sensing test paper and biosensor arrangement will more become polynary and complicated in the following detection market.Therefore, how can be simply and recognize the biosensor arrangement that different electrochemical biological sensing test paper are matched effectively, for the designer and manufacturer and user of test paper, also not less than being a problem demanding prompt solution.
Summary of the invention
At the defective that exists in the prior art, in order to save the aligning step of user before measurement, but still can keep the accuracy of measurement result, the purpose of this utility model is to provide a kind of electrochemical biological sensing test paper, it comprises the parameter identification element of being located at substrate back one end, when being connected with biosensor arrangement, this test paper can select to correspond to one group of correction parameter values of this batch test paper automatically, and then save the parameter correction step of carrying out by the user, simplify whole process of measurement, avoid the user to cause inaccurate testing result because of careless omission or operating mistake.
Technological means of the present utility model is to provide a kind of electrochemical biological sensing test paper, and it comprises a substrate, is provided with a positive and back side; One conductive layer is located on this substrate front side; One parameter identification element is located at an end of this substrate back and in order to corresponding one group of specific correction parameter values; One upper spacer is covered on this conductive layer; And a reaction zone, contact with this conductive layer and in order to react.
In preferred embodiment of the present utility model, parameter identification element in the electrochemical biological sensing test paper provided by the utility model comprises the different blocks more than four, by being interconnected or independence of each block, this parameter identification element can form multiple different form, and each form is corresponding to one group of specific correction parameter values, so when the test paper with special parameter identification element form was connected with a biological sensor device, this device just can be selected and the corresponding one group of correction parameter values of this batch test paper automatically.
In better embodiment, the parameter identification element in the electrochemical biological sensing test paper provided by the utility model comprises four blocks such as one first block, one second block, one the 3rd block and one the 4th block.By being interconnected or independence of these four blocks, the parameter identification element in the utility model can form 14 kinds of different forms, and each form is corresponding to one group of specific correction parameter values.
Parameter identification element in the electrochemical biological sensing test paper provided by the utility model can be made up of conductor; In preferred embodiment, this parameter identification element is made up of carbon, and the connection between each block of parameter identification element is separated definition with independent by laser-induced thermal etching or cutter etching.In preferred embodiment, this parameter identification element is located at the sensor side of substrate back.
As mentioned in the background technology, for the biosensor arrangement of recognizing that simply and effectively different electrochemical biological sensing test paper are matched, in electrochemical biological sensing test paper provided by the utility model, this conductive layer comprises at least three electrodes, and wherein at least one electrode has a variable-length district.The biological sensor device that this variable-length district matches with this electrochemical biological sensing test paper in order to identification.By changing the length of electrode, can adjust the resistance value of this electrode, when this electrochemical biological sensing test paper is connected with a biological sensor device, by the measurement of resistance value, the biosensor arrangement that can match in order to identification.In a preferred embodiment, this variable-length district has four kinds of different lengths, so can recognize four kinds of different biosensor arrangements.In addition, in a better embodiment, the electrode with this variable-length district is as a reference electrode.
In another preferred embodiment, this conductive layer comprises at least three electrodes, wherein at least two electrodes respectively have a variable-length district, utilize the respectively length ratio relation in this variable-length district, are recognized the biosensor arrangement that multiple different electrochemical biological sensing test paper is cooperated.
In aforementioned another preferred embodiment, respectively have a proportionate relationship between the length in this variable-length district, and this proportionate relationship is in order to recognize a biological sensor device that matches with this electrochemical biological sensing test paper.In this embodiment, this ratio is closed 1: 10 to 10: 1 the arbitrary ratio that can be.In another better embodiment of the present utility model, respectively this variable-length district has the form of four kinds of different lengths, and respectively the length ratio in this variable-length district closes 1: 4 to 4: 1 the arbitrary ratio that can be.
By changing the length of electrode, can adjust the resistance value of this electrode, when this electrochemical biological sensing test paper is connected with a biological sensor device, by the measurement of resistance value, the biosensor arrangement that can match in order to identification.By resistance (R) computing formula be: R=ρ (L/A), wherein ρ is a resistance coefficient, and L is a conductor length, and A is that cross-sectional area of conductor is long-pending.So when the sectional area of the resistance coefficient of conductor and conductor fixedly the time, the resistance value of this conductor and the length of this conductor are proportional.Factors such as the length of resistance coefficient and conductor, sectional area are irrelevant again, are the electrical properties of conductor material itself, determined by conductor material.In electrochemical biological sensing test paper provided by the utility model, the material of each electrode of conductive layer is fixed, so resistance coefficient is identical, and each electrode of this conductive layer is layed on the substrate in the mode of screen painting, so the sectional area of its each electrode of conductive layer of same electrochemical biological sensing test paper also can be considered identical, therefore, in electrochemical biological sensing test paper provided by the utility model, the resistance value of each electrode and the length of this electrode are proportional.
In electrochemical biological sensing test paper provided by the utility model, this conductive layer comprises a conductive silver glue-line and a conductive carbon bisque, this conductive carbon bisque is located on this conductive silver glue-line, and each conducting layer electrode comprises a corresponding conductive silver glue-line electrode and a conductive carbon bisque electrode, for example, conductive layer first electrode comprises conductive silver glue layer first electrode and conductive carbon bisque first electrode, conductive layer second electrode comprises conductive silver glue layer second electrode and conductive carbon bisque second electrode, and the rest may be inferred.
In another preferred embodiment again of the present utility model, this conductive layer comprises five electrodes, and wherein two electrodes respectively have a variable-length district, and this variable-length district is located at this conductive silver glue-line.Has a proportionate relationship between the length in two these variable-length districts, the biological sensor device that this proportionate relationship matches with this electrochemical biological sensing test paper in order to identification.In this embodiment, this proportionate relationship can be arbitrary ratio of 1: 10 to 10: 1.In another better embodiment again of the present utility model, two these variable-length districts respectively have the form of four kinds of different lengths, and the length ratio in two these variable-length districts relation can be arbitrary ratio of 1: 4 to 4: 1.
Form each electrode of this conductive layer jointly with form in parallel (hereinafter to be referred as carbon silver parallel circuit) owing to conductive silver glue-line in the conductive layer and conductive carbon bisque, resistance value formula by parallel circuit is: R=(R1xR2)/(R1+R2), as R1 during, calculate as can be known the resistance value R of this parallel circuit by this formula and will level off to R1 much smaller than R2.In electrode structure provided by the utility model, because minimum (the about 1.6x10 of resistance coefficient of silver
-8ρ/Ω m), makes the resistance value of the resistance value of conductive silver glue-line electrode, so the overall resistance of conducting layer electrode will level off to the resistance value of this conductive silver glue-line electrode much smaller than conductive carbon bisque electrode.
In electrochemical biological sensing test paper provided by the utility model, this variable-length district is located at this conductive silver glue-line.Conductive silver glue-line by a default length-specific in the variable-length district that makes this electrode (as the conductive silver glue-line of 1/4th, 1/2nd or 3/4ths length of default total length), make the only remaining conductive carbon bisque of this default part, thereby can reach the effect of the resistance value that changes this electrode.As previously mentioned, the resistance value of carbon silver parallel circuit will level off to the resistance value of this conductive silver glue-line, so under the situation that partially conductive elargol break is economized, because the resistance value of carbon silver part in parallel is minimum, make the total resistance value of this electrode will level off to the resistance value of only remaining conductive carbon powder layer segment in this electrode, that is the resistance value of this electrode will become to be similar to the relation of direct ratio with only remaining conductive carbon bisque length (being the length that the conductive silver glue break is economized part).
Say it for example, in electrochemical biological sensing test paper provided by the utility model, if it is the twice that the conductive silver glue break is economized length in conductive layer second electrode that the conductive silver glue break in conductive layer first electrode is economized length, then the resistance value of this conductive layer first electrode will be similar to the twice of this conductive layer second electrode resistance value, by that analogy.By aforesaid mode, the utility model can design the default part of different length on electrode, reach the effect of effective each electrode resistance value of control, and the proportionate relationship of two resistance between electrode values in the same electrochemical biological sensing test paper is calculated in utilization, to get rid of the long-pending influence of resistance coefficient and electrode sections, the resistance value proportionate relationship further is reduced to the length ratio relation in two electrode variable-length districts, the biosensor arrangement that matches in order to identification and different electrochemical biological sensing test paper, and need not to consider between different batch test paper because of the every difference in making (as the printing width of carbon dust layer, thickness, uniformity coefficient etc.) the error that may cause.
In electrochemical biological sensing test paper provided by the utility model, five electrodes of this conductive layer are conductive layer first electrode, conductive layer second electrode, conductive layer third electrode, conductive layer the 4th electrode and conductive layer the 5th electrode by a side to opposite side in regular turn.
In another preferred embodiment again, this conductive silver glue-line first electrode and this conductive silver glue-line third electrode respectively have a variable-length district, and has a proportionate relationship between the length in the length in this conductive silver glue-line first electrode variable-length district and this conductive silver glue-line third electrode variable-length district, the biological sensor device that this proportionate relationship matches with this electrochemical biological sensing test paper in order to identification.In this embodiment, this proportionate relationship can be arbitrary ratio of 1: 10 to 10: 1.In another better embodiment more of the present utility model, this conductive silver glue-line first electrode variable-length district and this conductive silver glue-line third electrode variable-length district respectively have the form of four kinds of different lengths, and the length ratio in this two variable-lengths district relation can be arbitrary ratio of 1: 4 to 4: 1.In addition, this conductive layer first electrode, this conductive layer second electrode formation short-circuit structure that is connected with this conductive layer third electrode.
In electrochemical biological sensing test paper provided by the utility model, can be by adjusting the respectively length ratio relation in this variable-length district, in order to corresponding to different biosensor arrangements.Say it for example, 1: 1 length ratio relation can be set at the biosensor arrangement corresponding to A, and 1: 2 length ratio relation is set at the biosensor arrangement corresponding to B that the rest may be inferred.In addition, this variable-length district also can optionally be located at the conductive silver glue-line of other wantonly two electrodes.For example this conductive silver glue-line first electrode and this conductive silver glue-line second electrode respectively have a variable-length district; Or this conductive silver glue-line second electrode and this conductive silver glue-line third electrode respectively have a variable-length district, corresponds respectively to different biosensor arrangements.In conjunction with above-mentioned dual mode, electrochemical biological sensing test paper provided by the utility model can spread out and stretch out multiple different electrode structure form, in order to cooperate multiple different biosensor arrangement.
In electrochemical biological sensing test paper provided by the utility model, contract in the electrode of this conductive layer, make the end of conductive layer at a distance of 0.1 to 1 millimeter, before correctly inserting biosensor arrangement, just start this device to avoid the electrochemical biological sensing test paper in the end of sensor side and this substrate in sensor side.
In electrochemical biological sensing test paper provided by the utility model, this conductive layer comprises at least three electrodes, and wherein at least one electrode is a reference electrode, and wherein at least one electrode is a working electrode.In preferred embodiment, this conductive layer comprises five electrodes, two electrodes formation short-circuit structure that is connected wherein, and jointly as a reference electrode, two electrodes are working electrode in addition, respectively in order to detect blood glucose value and the Hematocrit in the sample; And another electrode is a detecting electrode, whether enters reaction zone fully in order to detect sample.In a better embodiment, this conductive layer comprises five electrodes, this conductive layer second electrode formation short-circuit structure that is connected with this conductive layer third electrode wherein, and jointly as a reference electrode, this conductive layer the 4th electrode is a detecting electrode, and this conductive layer first electrode and this conductive layer the 5th electrode are working electrode.
In another better embodiment, this conductive layer comprises five electrodes, this conductive layer first electrode formation short-circuit structure that is connected with this conductive layer second electrode wherein, and jointly as a reference electrode, this conductive layer third electrode is a detecting electrode, and this conductive layer the 4th electrode and the 5th electrode are working electrode.
In electrochemical biological sensing test paper provided by the utility model, further comprise a median septum that is covered on conductive layer and the part substrate, and this median septum is provided with a groove in reactive end, be vertically and opening to this reactive end.This median septum is provided with an opening in addition, this opening adjacent to this groove and and this groove between be not interconnected, and corresponding to this reaction zone.
In electrochemical biological sensing test paper provided by the utility model, this upper spacer is provided with a perforate in order to ventilation corresponding to the opening part of median septum.And this upper spacer is provided with a breach in reactive end, in preferred embodiment, and this breach semicircular in shape or half elliptic.
In addition, in electrochemical biological sensing test paper provided by the utility model, this conductive carbon bisque is provided with one coarse section in the reactive end outside.This coarse section is the multistage straight line, and it prevents that in order to increase the roughness of substrate the reaction zone material from coming off, and increases the accuracy that detects.
In electrochemical biological sensing test paper provided by the utility model, further comprise a adhesive-layer between between this median septum and this upper spacer, in order to engaging this upper spacer and this median septum, and this adhesive-layer is provided with one second groove corresponding to the groove and the opening part of this median septum.In electrochemical biological sensing test paper provided by the utility model, can further comprise a insulation course between between this conductive layer and this median septum again, wherein this insulation course is provided with one the 3rd groove corresponding to the groove and the opening part of this median septum.
In sum, electrochemical biological sensing test paper provided by the utility model contrasts in background technology and existing product, has following beneficial effect:
Can make this device select to correspond to one group of correction parameter values of this batch test paper automatically when one, electrochemical biological sensing test paper provided by the utility model is connected with biosensor arrangement, and then save the parameter correction step of carrying out by the user, simplify whole process of measurement, avoid causing inaccurate testing result because of user's careless omission or operating mistake.
Two, remove from and need proofread and correct required extra manufacturing cost by the use chip card.
Three, the parameter identification element is located at the back side of substrate, is avoided placing substrate front side altogether, reduce the test paper and complexity and the manufacturing cost of biosensor arrangement on mechanism design that match with conductive layer.
Four, utilize the length in variable-length district in the conductive layer or the biosensor arrangement that its proportionate relationship matches with this test paper with identification, increase the convenience on using.
Description of drawings
Fig. 1 is the three-dimensional exploded view of the utility model one preferred embodiment.
Fig. 2 is the isometric front view of the utility model one preferred embodiment.
Fig. 3 is the rear isometric view of the utility model one preferred embodiment.
Fig. 4 is each distribution of electrodes synoptic diagram of conductive layer in the utility model one preferred embodiment.
Fig. 5 A-Fig. 5 N is the various forms of parameter identification element in the utility model.
Fig. 6 A-Fig. 6 E is the various forms in first kind of distribution of electrodes situation of the utility model and the conductive silver glue-line second electrode variable-length district.
Fig. 7 A-Fig. 7 E is the various forms in second kind of distribution of electrodes situation of the utility model and the conductive silver glue-line second electrode variable-length district.
Fig. 8 is the synoptic diagram of the third distribution of electrodes situation of the utility model.
Fig. 9 is the exploded view of the third distribution of electrodes situation of the utility model.
Figure 10 A-Figure 10 P is the partial electrode version (the variable-length district is located under the situation of conductive layer first electrode and conductive layer third electrode) of the third distribution of electrodes situation of the utility model.
Figure 11 is the three-dimensional exploded view of a better embodiment of the present utility model.
Figure 12 is the three-dimensional exploded view of another better embodiment of the present utility model.
Wherein, description of reference numerals is as follows:
10: substrate
102: substrate front side
104: substrate back
12: chamfering
20,20A, 20B: conductive layer
202,202A, 202B: conductive layer first electrode
204,204A, 204B: conductive layer second electrode
206,206A, 206B: conductive layer third electrode
208,208A, 208B: conductive layer the 4th electrode
209,209A, 209B: conductive layer the 5th electrode
22,22A, 22B: conductive silver glue-line
222,222A, 222B: conductive silver glue-line first electrode
2220,2220A, 2220B, 2220C, 2220D: the conductive silver glue-line first electrode variable-length district
224,224A, 224B: conductive silver glue-line second electrode
2240,2240A, 2240B, 2240C, 2240D, 2240E, 2240F, 2240G, 2240H: the conductive silver glue-line second electrode variable-length district
226,226B: conductive silver glue-line third electrode
2260,2260A, 2260B, 2260C, 2260D: conductive silver glue-line third electrode variable-length district
228,228B: conductive silver glue-line the 4th electrode
229,229B: conductive silver glue-line the 5th electrode
24,24A, 24B: conductive carbon bisque
240: coarse section
242,242B: conductive carbon bisque first electrode
244,244B: conductive carbon bisque second electrode
246,246B: conductive carbon bisque third electrode
248,248B: conductive carbon bisque the 4th electrode
249,249B: conductive carbon bisque the 5th electrode
30: the parameter identification element
30A: with first group of correction parameter values corresponding parameter identification element
30B: with second group of correction parameter values corresponding parameter identification element
30C: with the 3rd group of correction parameter values corresponding parameter identification element
30D: with the 4th group of correction parameter values corresponding parameter identification element
30E: with the 5th group of correction parameter values corresponding parameter identification element
30F: with the 6th group of correction parameter values corresponding parameter identification element
30G: with the 7th group of correction parameter values corresponding parameter identification element
30H: with the 8th group of correction parameter values corresponding parameter identification element
30I: with the 9th group of correction parameter values corresponding parameter identification element
30J: with the tenth group of correction parameter values corresponding parameter identification element
30K: with the 11 group of correction parameter values corresponding parameter identification element
30L: with the 12 group of correction parameter values corresponding parameter identification element
30M: with the 13 group of correction parameter values corresponding parameter identification element
30N: with the 14 group of correction parameter values corresponding parameter identification element
32: the second blocks of 31: the first blocks
34: the four blocks of 33: the three blocks
40: upper spacer 42: perforate
44: breach 50: median septum
52: groove 54: opening
60: 62: the second grooves of adhesive-layer
70: 72: the three grooves of insulation course
80: reaction zone 91: sensor side
92: reactive end
Embodiment
The utility model and some specific embodiments please refer to accompanying drawing and details are as follows.In fact, the utility model may be implemented with different forms, and should not be inferred to be and only limit to embodiment mentioned in the literary composition.
Nominal definition
Biosensor arrangement
Be meant with electrochemical biological sensing test paper provided by the utility model and match to detect the device of specific substance concentration in the sample, as blood glucose meter, cholesterol instrument, uric acid instrument etc.
Sensor side
Be meant that electrochemical biological sensing test paper provided by the utility model is when using and the contacted end of biosensor arrangement.
Reactive end
Be meant that electrochemical biological sensing test paper provided by the utility model when using and the end that reacts of sample, is an end at reaction zone place usually, and with respect to sensor side.
Fig. 1, Fig. 2 and three-dimensional exploded view, isometric front view and the rear isometric view that is respectively the utility model one preferred embodiment shown in Figure 3.As shown in Figure 1 to Figure 3, electrochemical biological sensing test paper provided by the utility model comprises a substrate 10, is provided with positive 102 and one back side 104; One conductive layer 20 is located on these substrate 10 fronts 102; One parameter identification element 30 is located at an end at these substrate 10 back sides 104 and in order to corresponding one group of specific correction parameter values; One upper spacer 40 is covered on this conductive layer 20; And a reaction zone 80, contact with this conductive layer 20 and in order to react.In addition, electrochemical biological sensing test paper provided by the utility model can further be divided into a sensor side 91 and a reactive end 92.
In the electrochemical biological sensing test paper provided by the utility model, this substrate 10 can be a rectangle lamellar body, and preferably this substrate 10 has electrical insulation characteristics.In preferred embodiment, four angles of this substrate 10 are chamfering 12, are stabbed or hurt by the tip accidentally when operating to avoid the user.This conductive layer 20 is coated on substrate 10 fronts 102, and this conductive layer comprises a conductive silver glue-line 22 and a conductive carbon bisque 24, and this conductive carbon bisque 24 is covered on the conductive silver glue-line 22.And this conductive layer 20 comprises three strip electrodes at least, comprises a working electrode and a reference electrode in this three strip electrode at least.In preferred embodiment, this conductive layer 20 is longitudinal extension and is parallel each other with the long limit of substrate 10 in this sensor side 91, and it is in order to contact with biosensor arrangement and to detect electrochemical change.
In a preferred embodiment, contract in the electrode of this conductive layer 20, make the end of this conductive layer 20 at a distance of 0.1 to 1 millimeter, before correctly inserting biosensor arrangement, just start this device to avoid the electrochemical biological sensing test paper in the end of sensor side 91 and this substrate 10 in sensor side 91.In a better embodiment, the end of this conductive layer 20 in the end of sensor side 91 and this substrate 10 in sensor side 91 is at a distance of 0.3 to 0.8 millimeter; In most preferred embodiment, the end of this conductive layer 20 in the end of sensor side 91 and this substrate 10 in sensor side 91 is at a distance of 0.5 to 0.6 millimeter.
As shown in Figure 1, in the electrochemical biological sensing test paper provided by the utility model, this upper spacer 40 is covered on this conductive layer 20, and this upper spacer 40 is provided with a perforate 42 in order to ventilation, and this upper spacer is provided with a breach 44 in reactive end 92.In preferred embodiment, this breach 44 semicirculars in shape or half elliptic, by the design of breach 44, and the area in increase sample sucting reaction district 80.Because breach 44 increases the area that sample sucks, therefore sample is not only from the side in the direction sucting reaction district 80 of parallel test paper, and also can be by in the different angles sucting reaction district, top 80, so not only increase the convenience of using, and also can increase the speed that sample sucks, and then increase the accuracy of test paper.
In electrochemical biological sensing test paper provided by the utility model, this reaction zone 80 is covered on substrate 10 and the partially conductive layer 20, it contains bioactivator (as enzyme), enzyme co-factor, stabilization agent (as high molecular polymer) and buffer solution etc., in order to react with sample.
Figure 4 shows that each distribution of electrodes situation of conductive layer in the utility model one preferred embodiment.In this embodiment, this conductive layer 20 of electrochemical biological sensing test paper provided by the utility model comprises five electrodes, be respectively conductive layer first electrode 202, conductive layer second electrode 204, conductive layer third electrode 206, conductive layer the 4th electrode 208 and conductive layer the 5th electrode 209, one end of these five electrodes all is longitudinal extension and parallel each other, and each conducting layer electrode comprises corresponding conductive carbon bisque electrode and conductive silver glue-line electrode, is respectively conductive silver glue-line first electrode 222, conductive silver glue-line second electrode 224, conductive silver glue-line third electrode 226, conductive silver glue-line the 4th electrode 228 and conductive silver glue-line the 5th electrode 229; And conductive carbon bisque first electrode 242, conductive carbon bisque second electrode 244, conductive carbon bisque third electrode 246, conductive carbon bisque the 4th electrode 248 and conductive carbon bisque the 5th electrode 249.In addition, this conductive silver glue-line second electrode 224 has a variable-length district 2240.
In preferred embodiment of the present utility model, the formation short-circuit structure that is connected of two electrodes in five electrodes of this conductive layer 20.With reference to figure 4, in better embodiment, this conductive layer second electrode 204 formation short-circuit structure that is connected with this conductive layer third electrode 206, and jointly as a reference electrode.
In preferred embodiment of the present utility model, one of them in five electrodes of this conductive layer 20 is a detecting electrode, whether enters this reaction zone fully in order to detect a sample.With reference to figure 4, in better embodiment, this conductive layer the 4th electrode 208 is a detecting electrode, whether enters this reaction zone fully in order to detect a sample.
In preferred embodiment of the present utility model, one of them in five electrodes of this conductive layer 20 is one in order to detect the working electrode of this sample blood glucose value.With reference to figure 4, in better embodiment, this conductive layer the 5th electrode 209 is one in order to detect the working electrode of this sample blood glucose value.
In preferred embodiment of the present utility model, one of them in five electrodes of this conductive layer 20 is one in order to detect the working electrode of this sample Hematocrit.With reference to figure 4, in better embodiment, this conductive layer first electrode 202 is one in order to detect the working electrode of this sample Hematocrit.
In electrochemical biological sensing test paper provided by the utility model, this parameter identification element 30 is located at an end at these substrate 10 back sides 104.With reference to figure 1 and Fig. 3, in preferred embodiment, this parameter identification element 30 is located at the sensor side 91 at these substrate 10 back sides 104, and forms relative position relation up and down with the conductive layer 20 that is positioned at these substrate 10 fronts 102, in order to contact with a biological sensor device and to carry out parameter identification.
Fig. 5 A-Fig. 5 N is depicted as the various forms of this parameter identification element 30 in the utility model.In the electrochemical biological sensing test paper provided by the utility model, this parameter identification element 30 comprises the different blocks more than four.In preferred embodiment, this parameter identification element 30 comprises four different blocks, is respectively first block 31, second block 32, the 3rd block 33 and the 4th block 34.By being interconnected or independence of each block, the parameter identification element 30 in the utility model can form 14 kinds of different forms, and each form is corresponding to one group of specific correction parameter values.In the utility model, the connection between these parameter identification element 30 each blocks is separated definition with independent by laser-induced thermal etching or cutter etching.Doublet among Fig. 5 A-Fig. 5 N is represented between each block and is interconnected, and double solid line is represented between each block through etching and independently is not interconnected.
Fig. 5 A is depicted as the form with first group of correction parameter values corresponding parameter identification element 30A, and wherein first block 31, second block 32, the 3rd block 33 and the 4th block 34 of this parameter identification element 30A all are interconnected.
Wantonly two blocks that Fig. 5 B and Fig. 5 C are depicted as in 30 4 blocks of this parameter identification element are interconnected and are not interconnected with all the other two blocks are independent, and all the other two blocks then are interconnected to each other.
Fig. 5 B is depicted as the form with second group of correction parameter values corresponding parameter identification element 30B, wherein first block 31 of this parameter identification element 30B and second block 32 are interconnected and the 3rd block 33 and the 4th block 34 are interconnected, and 34 of first block 31, second block 32 and the 3rd block 33, the 4th blocks are then independent not to be interconnected.
Fig. 5 C is depicted as the form with the 3rd group of correction parameter values corresponding parameter identification element 30C, wherein first block 31 of this parameter identification element 30C and the 3rd block 33 are interconnected and second block 32 and the 4th block 34 are interconnected, and 34 of first block 31, the 3rd block 33 and second block 32, the 4th blocks are then independent not to be interconnected.
Fig. 5 D is depicted as the form with the 4th group of correction parameter values corresponding parameter identification element 30D, and wherein first block 31, second block 32, the 3rd block 33 and the 4th block 34 of this parameter identification element 30D are all independent separately is not interconnected.
Fig. 5 E-Fig. 5 H is depicted as that arbitrary block in 30 4 blocks of this parameter identification element is independent not to be interconnected with other blocks and its excess-three block is interconnected.
Fig. 5 E is depicted as the form with the 5th group of correction parameter values corresponding parameter identification element 30E, and wherein first block 31 of this parameter identification element 30E is independent is not connected with other blocks and second block 32, the 3rd block 33 and the 4th block 34 are interconnected.
Fig. 5 F is depicted as the form with the 6th group of correction parameter values corresponding parameter identification element 30F, and wherein the 3rd block 33 of this parameter identification element 30F is independent is not connected with other blocks and first block 31, second block 32 and the 4th block 34 are interconnected.
Fig. 5 G is depicted as the form with the 7th group of correction parameter values corresponding parameter identification element 30G, and wherein the 4th block 34 of this parameter identification element 30G is independent is not connected with other blocks and first block 31, second block 32 and the 3rd block 33 are interconnected.
Fig. 5 H is depicted as the form with the 8th group of correction parameter values corresponding parameter identification element 30H, and wherein second block 32 of this parameter identification element 30H is independent is not connected with other blocks and first block 31, the 3rd block 33 and the 4th block 34 are interconnected.
Fig. 5 I-Fig. 5 N is depicted as that wantonly two blocks in 30 4 blocks of this parameter identification element are interconnected and all the other two blocks are all independent separately is not interconnected with other blocks.
Fig. 5 I is depicted as the form with the 9th group of correction parameter values corresponding parameter identification element 30I, and wherein first block 31 of this parameter identification element 30I and second block 32 are interconnected and the 3rd block 33 and the 4th block 34 are all independent separately is not interconnected.
Fig. 5 J is depicted as the form with the tenth group of correction parameter values corresponding parameter identification element 30J, and wherein the 3rd block 33 of this parameter identification element 30J and the 4th block 34 are interconnected and first block 31 and second block 32 are all independent separately is not interconnected.
Fig. 5 K is depicted as the form with the 11 group of correction parameter values corresponding parameter identification element 30K, and wherein first block 31 of this parameter identification element 30K and the 3rd block 33 are interconnected and second block 32 and the 4th block 34 are all independent separately is not interconnected.
Fig. 5 L is depicted as the form with the 12 group of correction parameter values corresponding parameter identification element 30L, and wherein second block 32 of this parameter identification element 30L and the 4th block 34 are interconnected and first block 31 and the 3rd block 33 are all independent separately is not interconnected.
Fig. 5 M is depicted as the form with the 13 group of correction parameter values corresponding parameter identification element 30M, and wherein second block 32 of this parameter identification element 30M and the 3rd block 33 are interconnected and first block 31 and the 4th block 34 are all independent separately is not interconnected.
Fig. 5 N is depicted as the form with the 14 group of correction parameter values corresponding parameter identification element 30N, and wherein first block 31 of this parameter identification element 30N and the 4th block 34 are interconnected and second block 32 and the 3rd block 33 are all independent separately is not interconnected.
In electrochemical biological sensing test paper provided by the utility model, this parameter identification element 30 is made of a conductor.In preferred embodiment, this parameter identification element 30 is made up of carbon.When the parameter identification element 30 that has particular form in this test paper is connected with a biological sensor device, this device can be sought out and the corresponding one group of correction parameter values of these parameter identification element 30 forms automatically by recognizing the connection or the independent situation of each block in this parameter identification element 30.
Fig. 6 A is depicted as first kind of distribution of electrodes situation of the utility model, and Fig. 6 B-Fig. 6 E is the various forms in this conductive silver glue-line second electrode variable-length district 2240 in first kind of distribution of electrodes situation of the utility model, wherein this conductive silver glue-line 22 is represented by dotted lines, and this conductive carbon bisque 24 is represented with solid line.In a preferred embodiment of the present utility model, this conductive layer second electrode 204 is connected with conductive layer third electrode 206 and forms short-circuit structure and can use as reference electrode jointly, and wherein this conductive silver glue-line second electrode 224 has a variable-length district 2240, recognizes the biosensor arrangement that matches with this electrochemical biological sensing test paper by the difference of resistance value.In better embodiment, this conductive silver glue-line second electrode variable-length district 2240 has four kinds of different lengths.Show among Fig. 6 B that this conductive silver glue-line second electrode variable-length district 2240A has the length of total length, and be connected with the sensor side 91 of this conductive silver glue-line second electrode 224.Show among Fig. 6 C that this conductive silver glue-line second electrode variable-length district 2240B has the length of 2/3rds total lengths, and be not connected with the sensor side 91 of this conductive silver glue-line second electrode 224.Show among Fig. 6 D that this conductive silver glue-line second electrode variable-length district 2240C has the length of 1/3rd total lengths, and be not connected with the sensor side 91 of conductive silver glue-line second electrode 224.Show among Fig. 6 E that this conductive silver glue-line second electrode variable-length district 2240D is default fully, and be not connected with the sensor side 91 of conductive silver glue-line second electrode 224.
By the narration before this instructions as can be known, the resistance value of this conductive layer second electrode 204 will become to be similar to the relation of direct ratio with the length of the conductive silver glue-line second electrode variable-length district 2240 default parts.When this electrochemical biological sensing test paper is connected with a biological sensor device, because the resistance value difference that this device can identification be caused because of the conductive silver glue-line second electrode variable-length district 2240 differences in length, and then confirm whether this electrochemical biological sensing test paper is the test paper that matches with this biosensor arrangement.
Fig. 7 A is depicted as second kind of distribution of electrodes situation of the utility model, the conductive layer first electrode 202A of this conductive layer 20A formation short-circuit structure that is connected with this conductive layer second electrode 204A wherein, and jointly as a reference electrode; And this conductive layer third electrode 206A is a detecting electrode; This conductive layer the 4th electrode 208A is a working electrode in order to detection sample blood glucose value; This conductive layer the 5th electrode 209A is a working electrode in order to detection sample Hematocrit.
Be depicted as the various forms in the conductive silver glue-line second electrode variable-length district 2240 in second kind of distribution of electrodes situation of the utility model in addition with reference to figure 7B, Fig. 7 C, Fig. 7 D and Fig. 7 E.Wherein this conductive silver glue-line second electrode 224A has a variable-length district 2240.In preferred embodiment, this conductive silver glue-line second electrode variable-length district 2240 has four kinds of different lengths.Show among Fig. 7 B that this conductive silver glue-line second electrode variable-length district 2240E has the length of total length, and be connected with the sensor side 91 of this conductive silver glue-line second electrode 224A.Show among Fig. 7 C that this conductive silver glue-line second electrode variable-length district 2240F has the length of 2/3rds total lengths, and be not connected with the sensor side 91 of the conductive silver glue-line second electrode 224A.Show among Fig. 7 D that this conductive silver glue-line second electrode variable-length district 2240G has the length of 1/3rd total lengths, and be not connected with the sensor side 91 of this conductive silver glue-line second electrode 224A.Show among Fig. 7 E that this conductive silver glue-line second electrode variable-length district 2240H is default fully, and be not connected with the sensor side 91 of this conductive silver glue-line second electrode 224A.
Fig. 8 is the synoptic diagram of the third distribution of electrodes situation of the utility model.With reference to figure 8, in another preferred embodiment of the present utility model, this conductive layer 20B comprises at least three electrodes, and wherein at least two electrodes respectively have a variable-length district 2220,2260.Wherein this conductive layer 20B comprises a conductive silver glue-line 22B and a conductive carbon bisque 24B, dotted line among the conductive layer 20B is represented conductive silver glue-line 22B, solid line is represented conductive carbon bisque 24B, this conductive carbon bisque 24B is located on this conductive silver glue-line 22B, forms each electrode of this conductive layer 20B jointly with the form of parallel connection.
As shown in Figure 8, in another preferred embodiment again of the present utility model, this conductive layer 20B comprises five electrodes, these five electrodes are the conductive layer first electrode 202B, the conductive layer second electrode 204B, conductive layer third electrode 206B, conductive layer the 4th electrode 208B and conductive layer the 5th electrode 209B by a side to opposite side in regular turn, and this conductive layer first electrode 202B, this conductive layer second electrode 204B formation short-circuit structure that is connected with this conductive layer third electrode 206B.Two electrodes in these five electrodes respectively have a variable- length district 2220,2260, and this variable- length district 2220,2260 is located at this conductive silver glue-line 22B.
Fig. 9 is the exploded view of the third distribution of electrodes situation of the utility model.As shown in Figure 9, in another preferred embodiment again of the present utility model, each conducting layer electrode comprises a corresponding conductive silver glue-line electrode and a conductive carbon bisque electrode, is respectively the conductive silver glue-line first electrode 222B, the conductive silver glue-line second electrode 224B, conductive silver glue-line third electrode 226B, conductive silver glue-line the 4th electrode 228B and conductive silver glue-line the 5th electrode 229B; And the conductive carbon bisque first electrode 242B, the conductive carbon bisque second electrode 244B, conductive carbon bisque third electrode 246B, conductive carbon bisque the 4th electrode 248B and conductive carbon bisque the 5th electrode 249B.With reference to figure 8 and Fig. 9, wherein this conductive layer first electrode 202B comprises this conductive silver glue-line first electrode 222B and this conductive carbon bisque first electrode 242B, this conductive layer second electrode 204B comprises this conductive silver glue-line second electrode 224B and this conductive carbon bisque second electrode 244B, and the rest may be inferred.
In another preferred embodiment more of the present utility model, this conductive silver glue-line first electrode 222B has a variable-length district 2220, and this conductive silver glue-line third electrode 226B has a variable-length district 2260.In another better embodiment again, this conductive silver glue-line first electrode variable-length district 2220 respectively has the form of four kinds of different lengths with this conductive silver glue-line third electrode variable-length district 2260.
Figure 10 A-Figure 10 P is the partial electrode version of the third distribution of electrodes situation of the utility model.Shown in Figure 10 A-Figure 10 P, be located in the variable-length district under the situation of this conductive silver glue-line first electrode 222B and this conductive silver glue-line third electrode 226B, because this variable-length district 2220 respectively, 2260 have the form of four kinds of different lengths respectively, be respectively (the variable-length district 2220A that has total length length, variable-length district 2260A), 2/3rds total length length (variable-length district 2220B, variable-length district 2260B), / 3rd total length length (variable-length district 2220C, variable-length district 2260C) and default fully (the variable-length district 2220D in this variable-length district, variable-length district 2260D) four kinds of length forms such as, so after the permutation and combination Figure 10 A-Figure 10 P totally ten six kinds of electrode structure forms are arranged, can correspond respectively to different biosensor arrangements.
Electrode structure form with Figure 10 B is an example, and this conductive silver glue-line first electrode variable-length district 2220A has total length length and this conductive silver glue-line third electrode variable-length district 2260B has 2/3rds total length length; The electrode structure form of Figure 10 C then has total length length for this conductive silver glue-line first electrode variable-length district 2220A and this conductive silver glue-line third electrode variable-length district 2260C has three minutes a total length length, and the rest may be inferred.
By the narration before this instructions as can be known, in previous embodiment, has a proportionate relationship between the length in the length in this conductive silver glue-line first electrode variable-length district 2220 and this conductive silver glue-line third electrode variable-length district 2260.Electrode structure form with Figure 10 B is an example, and this proportionate relationship is 3: 2; Electrode structure form with Figure 10 C is an example, and this proportionate relationship is 3: 1, and the rest may be inferred.In previous embodiment, this proportionate relationship can be arbitrary ratio of 1: 10 to 10: 1; In another better embodiment again, this proportionate relationship can be arbitrary ratio of 1: 4 to 4: 1.In electrode structure provided by the utility model, the biological sensor device that this proportionate relationship matches with this electrochemical biological sensing test paper in order to identification.
Figure 11 is the three-dimensional exploded view of the utility model one better embodiment.By shown in Figure 11, electrochemical biological sensing test paper provided by the utility model can further comprise a median septum 50 that is covered on this conductive layer 20 and the part substrate 10.Wherein this median septum 50 is provided with a groove 52 in reactive end 92, be vertically and opening to this reactive end 92.In addition, this median septum 50 is provided with an opening 54, this opening 54 adjacent to this groove 52 and and 52 of this grooves be not interconnected, and corresponding to reaction zone 80.
As shown in figure 11, in of the present utility model one better embodiment, this conductive carbon bisque 24 is provided with one coarse section 240 in reactive end 92 outsides, and preferably, this coarse section 240 can be a straight line or multistage straight line.This coarse section 240 can be conductive material, and this coarse section 240 is more preferably formed by carbon dust.In addition, also can make for this coarse section 240 by non-conductive material.This coarse section 240 roughness in order to increase substrate 10 increases reaction zone 80 materials and attaches intensity, prevents that reaction zone 80 materials from coming off.In a preferred embodiment of the present utility model, this coarse section 240 outside that is positioned near reaction zone 80.
Electrochemical biological sensing test paper provided by the utility model can further comprise an adhesive-layer 60 between 40 of this median septum 50 and this upper spacers again, in order to connect this upper spacer 40 and this median septum 50.Wherein this adhesive-layer 60 is provided with one second groove 62 corresponding to the groove 52 and opening 54 places of this median septum 50.In preferred embodiment of the present utility model, this adhesive-layer 60 is by polyethylene terephthalate (Polyethylene Terephthalate, abbreviation PET) form, and in upper and lower surface coating adhesive material such as glue, in order to bonding this upper spacer 40 and this median septum 50.
Figure 12 is the three-dimensional exploded view of the another better embodiment of the utility model.By shown in Figure 12, electrochemical biological sensing test paper provided by the utility model can further comprise an insulation course 70 between 50 of this conductive layer 20 and this median septums again, and this insulation course 70 is provided with one the 3rd groove 72 corresponding to the groove 52 and opening 54 places of this median septum 50.
Though previous embodiment illustrates the concrete fact of the present utility model, should be appreciated that any possible correction and change be not all departing from spirit of advocating in claims and protection domain.
Claims (30)
1. electrochemical biological sensing test paper, it comprises:
One substrate is provided with a positive and back side;
One conductive layer is located on this substrate front side;
One parameter identification element is located at an end of this substrate back and in order to corresponding one group of specific correction parameter values;
One upper spacer is covered on this conductive layer; And
One reaction zone contacts with this conductive layer and in order to react.
2. electrochemical biological sensing test paper according to claim 1 is characterized in that, this parameter identification element have by laser-induced thermal etching or cutter etching form multiple multi-form.
3. electrochemical biological sensing test paper according to claim 2 is characterized in that, this parameter identification element comprises the different blocks more than four.
4. electrochemical biological sensing test paper according to claim 3 is characterized in that, this parameter identification element comprises four different blocks, is respectively first block, second block, the 3rd block and the 4th block.
5. electrochemical biological sensing test paper according to claim 4 is characterized in that, these four blocks all are interconnected.
6. electrochemical biological sensing test paper according to claim 4 is characterized in that, wantonly two blocks in these four blocks are interconnected and are not interconnected with all the other two blocks are independent, and all the other two blocks then are interconnected to each other.
7. electrochemical biological sensing test paper according to claim 4 is characterized in that, these four blocks are all independent separately not to be interconnected with other blocks.
8. electrochemical biological sensing test paper according to claim 4 is characterized in that, the arbitrary block in these four blocks independently is not interconnected with other blocks and its excess-three block is interconnected.
9. electrochemical biological sensing test paper according to claim 4 is characterized in that, wantonly two blocks in these four blocks are interconnected and all the other two blocks are all independent separately is not interconnected with other blocks.
10. according to the arbitrary described electrochemical biological sensing test paper of claim 1 to 9, it is characterized in that this parameter identification element is made of a conductor.
11. electrochemical biological sensing test paper according to claim 10 is characterized in that, this conductor is a carbon.
12. electrochemical biological sensing test paper according to claim 11, it is characterized in that, this conductive layer comprises at least three electrodes, and wherein at least one electrode has a variable-length district of a biological sensor device that matches with this electrochemical biological sensing test paper in order to identification.
13. electrochemical biological sensing test paper according to claim 12 is characterized in that, this variable-length district has four kinds of different length forms.
14. electrochemical biological sensing test paper according to claim 13 is characterized in that, the electrode with this variable-length district is a reference electrode.
15. electrochemical biological sensing test paper according to claim 12 is characterized in that, at least two electrodes respectively have a variable-length district in this conductive layer.
16. electrochemical biological sensing test paper according to claim 15 is characterized in that, respectively has a proportionate relationship of a biological sensor device that matches with this electrochemical biological sensing test paper in order to identification between the length in this variable-length district.
17. electrochemical biological sensing test paper according to claim 16 is characterized in that, this proportionate relationship is arbitrary ratio of 1: 10 to 10: 1.
18. electrochemical biological sensing test paper according to claim 17 is characterized in that, respectively this variable-length district has four kinds of different length forms.
19. electrochemical biological sensing test paper according to claim 18 is characterized in that, this proportionate relationship is arbitrary ratio of 1: 4 to 4: 1.
20. electrochemical biological sensing test paper according to claim 15, it is characterized in that, this conductive layer comprises a conductive silver glue-line and a conductive carbon bisque, this conductive carbon bisque is covered on this conductive silver glue-line, and each conducting layer electrode comprises a corresponding conductive silver glue-line electrode and a conductive carbon bisque electrode.
21. electrochemical biological sensing test paper according to claim 20 is characterized in that, this conductive layer comprises five electrodes, and wherein two electrodes respectively have a variable-length district.
22. electrochemical biological sensing test paper according to claim 21 is characterized in that, this variable-length district is located at this conductive silver glue-line.
23. electrochemical biological sensing test paper according to claim 22 is characterized in that, has a proportionate relationship of a biological sensor device that matches with this electrochemical biological sensing test paper in order to identification between the length in two these variable-length districts.
24. electrochemical biological sensing test paper according to claim 23 is characterized in that, this proportionate relationship is arbitrary ratio of 1: 10 to 10: 1.
25. electrochemical biological sensing test paper according to claim 24 is characterized in that, respectively this variable-length district has four kinds of different length forms.
26. electrochemical biological sensing test paper according to claim 25 is characterized in that, this proportionate relationship is arbitrary ratio of 1: 4 to 4: 1.
27. electrochemical biological sensing test paper according to claim 26, it is characterized in that, five electrodes of this conductive layer are conductive layer first electrode, conductive layer second electrode, conductive layer third electrode, conductive layer the 4th electrode and conductive layer the 5th electrode by a side to opposite side in regular turn, and this conductive silver glue-line first electrode and this conductive silver glue-line third electrode respectively have a variable-length district.
28. electrochemical biological sensing test paper according to claim 27 is characterized in that, at least two electrodes formation short-circuit structure that is connected in this conductive layer, and jointly as a reference electrode.
29. electrochemical biological sensing test paper according to claim 28 is characterized in that, this conductive layer first electrode, this conductive layer second electrode formation short-circuit structure that is connected with this conductive layer third electrode, and jointly as a reference electrode.
30. electrochemical biological sensing test paper according to claim 29, it is characterized in that, this electrochemical biological sensing test paper is further divided into a sensor side and a reactive end, and wherein the end of this conductive layer in the end of this sensor side and this substrate in this sensor side at a distance of 0.1 to 1 millimeter.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102192929A (en) * | 2010-03-12 | 2011-09-21 | 泰博科技股份有限公司 | Electrochemical biosensing test strip, and method for identifying biosensor apparatus |
| CN108213719A (en) * | 2018-01-06 | 2018-06-29 | 武汉吉事达科技股份有限公司 | A kind of laser production method of multi-electrode blood sugar test paper |
| WO2023246298A1 (en) * | 2022-06-21 | 2023-12-28 | 爱森斯(江苏)生物科技有限公司 | Electrochemical biosensor and preparation method therefor |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102192929A (en) * | 2010-03-12 | 2011-09-21 | 泰博科技股份有限公司 | Electrochemical biosensing test strip, and method for identifying biosensor apparatus |
| CN108213719A (en) * | 2018-01-06 | 2018-06-29 | 武汉吉事达科技股份有限公司 | A kind of laser production method of multi-electrode blood sugar test paper |
| WO2023246298A1 (en) * | 2022-06-21 | 2023-12-28 | 爱森斯(江苏)生物科技有限公司 | Electrochemical biosensor and preparation method therefor |
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