CN102253085A - Correction bar, detector bar with correction code and detection device - Google Patents
Correction bar, detector bar with correction code and detection device Download PDFInfo
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- CN102253085A CN102253085A CN2011100596020A CN201110059602A CN102253085A CN 102253085 A CN102253085 A CN 102253085A CN 2011100596020 A CN2011100596020 A CN 2011100596020A CN 201110059602 A CN201110059602 A CN 201110059602A CN 102253085 A CN102253085 A CN 102253085A
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Abstract
The invention discloses a correction bar, a detector bar with a correction code and a detection device; correction code information is coded by different resistors or resistor combination, and these resistors are fixedly mounted on an extra correction bar, or directly and fixedly mounted on a detector bar; therefore, by reading the coded resistance value on the correction bar or the detector bar with a correction code, the detection device can call a correction parameter (correction code) of the detection bar of the batch which is stored in the detection device in advance. The invention has the characteristics of good correction effect, simple structure, and low manufacturing cost.
Description
Technical field
The present invention relates to the clinical analysis chemical field, be specifically related to be used for employed a kind of calibration bars, the detector bar that contains correction codes and pick-up unit in the disposable biological sensor detection system of analysis of biological samples component concentrations to be measured.
Background technology
The disposable biological sensor detection system is mainly used in component concentrations to be measured in detection and the analysis of biological samples, is widely used in the detection of projects such as full blood glucose, uric acid, cholesterol, triglyceride, haemoglobin, glycosylated hemoglobin, lactic acid, beta hydroxybutyric acid or glutamic-pyruvic transaminase at present.The disposable biological sensor detection system mainly is made of detector bar and pick-up unit.Wherein detector bar is disposable jettisonable, detector bar is that the matrix of sensor is that the two ends of circuit substrate, circuit substrate are respectively equipped with reaction zone and sampling contact regions, be communicated with by the conducting objects that is printed on the circuit substrate between reaction zone and the sampling contact regions, the encapsulation emulsion sheet is overlying on the surface of circuit substrate, and conducting objects and reaction zone beyond the sampling contact regions are covered.Pick-up unit then comprises shell and is installed in the testing circuit of enclosure that shell is provided with slot, button and display screen.Testing circuit is the core of pick-up unit, and it mainly is made up of power circuit, microprocessor, interface circuit and amplifying circuit.Wherein button is connected with microprocessor, and interface circuit is positioned at the slot place on the shell, and interface circuit links to each other with the input end of microprocessor through amplifying circuit, and the output terminal of microprocessor is connected with display screen.When detecting, a sample end of contact regions of detector bar is inserted in the slot of pick-up unit, behind the device prompting application of sample to be detected, with the biological sample siphon or drip in the conversion zone of test-strips, pick-up unit carries out showing testing result after the coherent detection.
Because detector bar can be because of the existing uncertainty of factors such as starting material and process conditions in manufacture process, cause the difference that exists between every batch of detector bar more or less, this just need make the correction parameter of this batch detector bar according to the test performance of the detector bar of each batch, and correction parameter is commonly referred to as correction codes.Every batch of detector bar needs according to the code of this batch detector bar existing fixedly algorithm to be proofreaied and correct before test like this, promptly need storage this batch detector bar correction parameter (correction codes) in pick-up unit in advance, could guarantee that test result meets the predetermined accuracy scope.Traditional bearing calibration need be by button manual input correction codes on pick-up unit, yet this manual input mode is not only loaded down with trivial details but also bother, according to statistics, 15% test meeting makes testing result can not get guaranteeing owing to correctly not importing correction codes by hand, even obtains full of prunes result.Exempt from the mode of manual input correction codes though occurred some at present, as adopt the method for storage chip, be that pick-up unit also is equipped with one for the slot that inserts storage card except being equipped with the slot that uses for detector bar, per tens person-portions of storage card (storage chip) are equipped with one.Yet these class methods need not only can make that the structure of detecting instrument becomes complicated, cost up, and adopt the storage card of storage chip formula also to have drawbacks such as cost height.
The explanation of division name in the literary composition:
Coding resistor: i.e. resistance.As direct insertion resistance, Chip-R, slurry formula printed resistor etc.
Calibration bars: be installed on the circuit substrate by coding resistor and form.Other addresses have: coded card, correction card, code card, means for correcting etc.
Detector bar: traditional strip, analoids, electrode slice, disposable biological sensor etc.
The detector bar that contains correction codes: be packed on traditional detector bar by coding resistor and integrate one and form.
Pick-up unit: be commonly referred to as instrument or detecting instrument; As blood glucose meter, hemoglobin analyser etc.
Sampling contact: detector bar or contain reaction zone on the detector bar of correction codes and the contact point of pick-up unit.
Coding contact: calibration bars or contain the contact point of coding resistor and pick-up unit on the detector bar of correction codes.
Summary of the invention
Technical matters to be solved by this invention provides a kind of detection that is used for projects such as full blood glucose, uric acid, cholesterol, triglyceride, haemoglobin, glycosylated hemoglobin, lactic acid, beta hydroxybutyric acid or glutamic-pyruvic transaminase, and can make things convenient for, import at low cost a kind of calibration bars of batch detector bar correction codes, the detector bar that contains correction codes and the pick-up unit of fitting.
For achieving the above object, the present invention is by different resistance or the incompatible coding correction codes of resistor group information, and these resistance are packed in extra calibration bars or directly are packed on the detector bar, pick-up unit calls the correction parameter (correction codes) that is stored in the detector bar of this batch in the pick-up unit in advance by reading calibration bars or containing coding resistor value on the detector bar of correction codes like this.
A kind of calibration bars that the present invention is designed comprise body, described body mainly by circuit substrate, and circuit substrate the coding resistor district and the coding contact district that are provided with form; Wherein the coding resistor district comprises the coding resistor more than 1 or 1, and the coding contact district comprises 2 or 2 above coding contacts; Above-mentioned coding resistor district and coding contact district are communicated with by conducting objects, and promptly the two ends of each coding resistor respectively link to each other with 1 coding contact, and wherein the coding contact of end connection is contact, simulation ground, and the coding contact of other end connection is the signals collecting contact.
In the such scheme, described coding resistor district preferably lays respectively at vertically relative two ends of circuit substrate with the coding contact district.
In the such scheme, preferably shared 1 the public contact, simulation ground of all coding resistors.
In the such scheme, the number of described coding resistor is preferably 2～4, and the resistance of these coding resistors is preferably between 100 Ω～200k Ω.
Coding resistor promptly can be a fixed resistance, also can be adjustable resistance.Wherein adjustable resistance is by print, install the coding resistor that can adjust resistance for the later stage in advance on circuit substrate, after having determined the correction codes of this lot number detector bar in the later stage then, adjust to be packed in by modes such as laser resistor trimming, etchings again and be used to the resistance of encoding on the calibration bars, make it to meet the mode of production such as predictive encoding Standard resistance range and obtain.
In the such scheme, described coding resistor is preferably SMD resistance, fixed slurry printed resistor or adjustable slurry printed resistor.
In the such scheme, the resistance region surface of described circuit substrate preferably is coated with encapsulation emulsion sheet and/or print overlay layer.
A kind of detector bar that contains correction codes that the present invention is designed comprises reaction zone and sampling contact regions that circuit substrate and circuit substrate are provided with, is communicated with by the conducting objects that is printed on the circuit substrate between reaction zone and the sampling contact regions.Also be provided with coding resistor district and coding contact district on the described circuit substrate; Wherein the coding resistor district comprises the coding resistor more than 1 or 1, and the coding contact district comprises 2 or 2 above coding contacts; Above-mentioned coding resistor district and coding contact district are communicated with by conducting objects, and promptly the two ends of each coding resistor respectively link to each other with 1 coding contact, and wherein the coding contact of end connection is contact, simulation ground, and the coding contact of other end connection is the signals collecting contact.
In the such scheme, described sampling contact regions is identical with residing position on circuit substrate, coding contact district.
In the such scheme, preferably shared 1 the public contact, simulation ground of all coding resistors.
In the such scheme, the number of described coding resistor is preferably 2～4, and the resistance of these coding resistors is preferably between 100 Ω～200k Ω.
Coding resistor promptly can be a fixed resistance, also can be adjustable resistance.Wherein adjustable resistance is by print, install the coding resistor that can adjust resistance for the later stage in advance on circuit substrate, after having determined that in the later stage this batch contains the correction codes of detector bar of correction codes then, adjust to be packed in by modes such as laser resistor trimming, etchings again and be used to the resistance of encoding on the calibration bars, make it to meet the mode of production such as predictive encoding Standard resistance range and obtain.
In the such scheme, described coding resistor is preferably SMD resistance, fixed slurry resistance or adjustable slurry resistance.
In the such scheme, the resistance region surface of described circuit substrate preferably is coated with encapsulation emulsion sheet and/or print overlay layer.
In order to cooperate above-mentioned calibration bars or to contain the detector bar of correction codes, a kind of pick-up unit that the present invention is designed comprises shell and is installed in the testing circuit of enclosure that shell is provided with slot, button and display screen; Wherein testing circuit mainly is made up of power circuit, microprocessor, interface circuit and amplifying circuit; Button is connected with microprocessor, and interface circuit is positioned at the slot place on the shell, and interface circuit links to each other with the input end of microprocessor through amplifying circuit, and the output terminal of microprocessor is connected with display screen; Be provided with analog-to-digital conversion module, coding correction module and memory module in the described microprocessor, wherein the input end of analog-to-digital conversion module connects amplifying circuit, and the output terminal of analog to digital conversion circuit connects the input end of coding correction module; Above-mentioned coding correction module is connected with the storer that stores 1 correction codes at least, and the coding that this coding correction module is reflected according to the coding contact district that analog to digital conversion circuit is passed back is proofreaied and correct resistance value and called the correction codes that is stored in this batch detector bar in the storer in advance.
The present invention compared with prior art, the present invention has following characteristics:
1, the calibration bars that have coding resistor by additional designs, or the mode of directly on existing detector bar, setting up coding resistor corrections of encoding, its calibration result is better, structure is more simple, manufacturing cost is also cheaper;
2, since calibration bars, detector bar and the detector bar that contains correction codes all with circuit substrate as matrix, therefore only need calibration bars, detector bar and the contact regions that contains the detector bar of correction codes are made identical shape and size, promptly can realize the shared of slot, can reduce like this pick-up unit slot quantity, avoid materials such as dust or humidity from slot, to enter verifying attachment causing the oxidation of testing circuit and corrosion and influence testing result;
3, set up on traditional detector bar when coding resistor and integrate when forming the integrally formed detector bar that contains correction codes of the present invention, each detector bar in use can both by pick-up unit read automatically this detector bar correction parameter, thereby can effectively avoid because of the user forget the input detector bar the incorrect risk of the result that correction parameter caused.
Description of drawings
Fig. 1 is a kind of calibration bars;
Fig. 2 .1a is a kind of front that contains the detector bar of correction codes;
Fig. 2 .1b is a kind of reverse side that contains the detector bar of correction codes;
Fig. 2 .2 is the another kind of detector bar that contains correction codes;
Fig. 2 .3 contains the detector bar of correction codes for another;
Fig. 3 is a kind of schematic block circuit diagram of pick-up unit.
Indicate among the figure: 1, circuit substrate; 2, coding contact district; 3, coding resistor district; 4, sampling contact regions; 5, reaction zone; 6, coding resistor; 7, conducting objects; 8, coding contact; 9, encapsulation emulsion sheet; 10, print overlay layer
Embodiment
The present invention is by different resistance or the incompatible coding correction codes of resistor group information, pick-up unit calls the correction codes that is stored in the detector bar of this batch in the pick-up unit in advance by reading calibration bars or containing coding resistor 6 values on the detector bar of correction codes like this.Can realize that foregoing invention purpose embodiment has two kinds: embodiment one is the structure that does not change existing detector bar, directly mixes calibration bars for the detector bar of same batch (promptly having identical correction codes), has coding resistor 6 on these calibration bars; Embodiment two is directly to set up coding resistor 6 to be integrated into the detector bar that contains correction codes on traditional detector bar.
The related a kind of calibration bars of embodiment one as shown in Figure 1, these calibration bars mainly are made up of coding resistor district 3 and the coding contact district 2 that circuit substrate 1 and circuit substrate 1 are provided with.3 in above-mentioned coding resistor district comprises the coding resistor 6 more than 1 or 1, by the resistance value of setting coding resistor 6 form coding represent the correction codes of correspondence batch detector bar.In the correction codes value input detection device with coding resistor 6 representatives, described coding contact district 2 comprises more than 2 or 2 and the coding contact 8 that matches with the structural circuit of pick-up unit.Above-mentioned coding resistor district 3 and coding contact district 2 are communicated with by conducting objects 7, the two ends that are each coding resistor 6 respectively link to each other with 1 coding contact 8, wherein the coding contact 8 of end connection is contact, simulation ground, the coding contact 8 that the other end connects be the signals collecting contact, and this that is to say that the contact number in coding contact district 2 just is 2 times of coding resistor 6 numbers in coding resistor district 3.And in the present embodiment, in order to save the contact number, to reduce the size in coding contact district 2, the contact, simulation ground that above-mentioned all coding resistors 6 are connect can sharedly be 1 public contact, simulation ground, and remaining signals collecting contact is respectively as coding contact 8, this moment, one end of above-mentioned coding resistor 6 all linked to each other with common, and the other end then is connected on the different coding contact 8.
In the present embodiment, the shape of described circuit substrate 1 and thickness, particularly insert pick-up unit one end shape should with the slot shape offered on the pick-up unit and size with match, can be irregularly shaped as the shape of circuit substrate 1 for strip, ellipse, raindrop shape or other.The thickness of circuit substrate 1 is between 0.05mm～2mm.For calibration bars can be inserted in the slot of pick-up unit and by its reliable identification more smoothly, the described circuit substrate 1 of present embodiment is the strip of thickness between 0.2mm～0.4mm.For the ease of pulling and pushing and reading of calibration bars, in the present embodiment, coding resistor district 3 and coding contact district 2 should be positioned on vertical opposite end of circuit substrate 1.In addition, the distribution of the pros and cons of coding contact 8 on circuit substrate 1 in the above-mentioned coding contact district 2 also should adapt with the metal contact of the interface circuit at the slot place of pick-up unit, to guarantee that the coding resistor 6 on the calibration bars can be by the identification of contact detected circuit.When the metal contact of the interface circuit of pick-up unit was positioned at the same side of slot, all contacts in described coding contact district 2 should be distributed on the surface, the same side of circuit substrate 1; And when the metal contact of the interface circuit of pick-up unit was positioned at the relative both sides of slot, all contacts in described coding contact district 2 can correspondingly be distributed on the positive and negative both side surface of circuit substrate 1.In the present embodiment, described coding contact district 2 is positioned on the surface, the same side of circuit substrate 1.And the metal contact that need not to change its interface circuit in order to continue to use existing pick-up unit is arranged, and in the present embodiment, the sampling contact that the coding contact 8 of above-mentioned calibration bars distributes with existing detector bar distributes basic identical.
The number of coding resistor 6 and pick-up unit have determined the group/cording quantity of calibration bars to the accuracy of identification of resistance, under the situation of N coding resistor 6 array combination, can discern the resistance M that just can encode for M
NIndividual correction parameter.In the present invention, the number of selected coding resistor 6 is 1～10, and the resistance of these coding resistors 6 is between 1 Ω～1000k Ω.Consider the factor of encoding precision and cost, selected coding resistor 6 numbers of the present invention are preferably 2～4, and the resistance of these coding resistors 6 is preferably between 100 Ω～200k Ω.The coding resistor 6 that is connected on the contact can adopt known resistance form at present, as direct insertion resistance, SMD resistance, fixed slurry printed resistor or adjustable slurry printed resistor.Direct insertion resistance, SMD resistance and fixed slurry printed resistor have all had fixing resistance before the circuit substrate 1 on installing or printing.Adjustable slurry printed resistor then is by print, install the coding resistor 6 that can adjust resistance for the later stage in advance on circuit substrate 1, detector bar production link in the later stage has distributed sensor sensing things such as enzyme, electron mediator, and determined by sample after the correction codes of this lot number detector bar, adjust to be packed in by modes such as laser resistor trimming, etchings again and be used to the resistance of encoding on the calibration bars, make it to meet the predictive encoding Standard resistance range.When selecting direct insertion resistance or SMD resistance for use, the mode that can use outside weldings or conductive adhesive is fixed on coding resistor 6 and realizes on the circuit substrate 1 being electrically connected.When selecting adjustable slurry resistance or fixed slurry resistance for use, can use the reticulated printing machine to be printed on the circuit substrate 1 that PET sheet, epoxy resin board or phenolics plate that thickness is fit to constituted.In the preferred embodiment of the present invention, select adjustable slurry resistance for use, this adjustable slurry resistance can use the mode of laser accurate resistance trimming to adjust the resistance of each coding resistor 6, makes each coding resistor 6 meet predetermined Standard resistance range.For fear of the oxidation of coding resistor 6 and the encoding error that causes, the surface of circuit substrate 1 of the present invention also is coated with encapsulation emulsion sheet 9 and/or print overlay layer 10, by this encapsulation emulsion sheet 9 or print overlay layer 10 is got up with relevant conducting objects 7 encapsulation in the coding resistor district 3 beyond the coding contact district 2.
Embodiment one need be equipped with calibration bars for same batch detector bar.During use, calibration bars are inserted in the slot of means for correcting, the coding contact district 2 on the calibration bars contacts with metal contact on the means for correcting interface circuit, and the voltage signal of the coding resistor 6 values reaction on the calibration bars is read in the microprocessor.Size according to the resistance of coding resistor 6, the varying voltage signal value that the coding contact 8 that is attached thereto returns is delivered to microprocessor after amplifying, microprocessor is handled the voltage signal more than above-mentioned 1 road or 1 tunnel, and calls the correction codes that is stored in this batch detector bar in the pick-up unit in advance according to result.Afterwards, calibration bars can be taken out from pick-up unit.When detecting, one end of the sampling contact regions 4 of traditional detection bar is inserted in the slot of pick-up unit, with the biological specimen siphon or drip in the reaction zone 5 of detector bar, pick-up unit begins to detect then, and pick-up unit carries out showing testing result after the coherent detection.
Embodiment two related a kind of detector bars that contain correction codes comprise that mainly reaction zone 5, sampling contact regions 4, coding resistor district 3 and coding contact district 2 that circuit substrate 1 and circuit substrate 1 are provided with form.Establish on the reaction zone 5 and inhale Hongkou and vent port.Be communicated with by the conducting objects 7 that is printed on the circuit substrate 1 between reaction zone 5 and the sampling contact regions 4.3 in above-mentioned coding resistor district comprises the coding resistor 6 more than 1 or 1, calls the correction codes of institute's correspondence batch detector bar by the resistance value institute formation information of setting coding resistor 6.For with in the coding resistor 6 formed information input detection devices, described coding contact district 2 comprises more than 2 or 2 and the contact of matching with the structural circuit of pick-up unit.Above-mentioned coding resistor district 3 and coding contact district 2 are communicated with by conducting objects 7, the two ends that are each coding resistor 6 respectively link to each other with 1 coding contact 8, wherein the contact of end connection is contact, simulation ground, the contact that the other end connects is the signals collecting contact, and this contact number that is to say coding contact district 2 just is 2 times of coding resistor 6 numbers in coding resistor district 3.And in the present embodiment, in order to save the contact number, to reduce the size in coding contact district 2, the contact, simulation ground that above-mentioned all coding resistors 6 are connect can sharedly be 1 public contact, simulation ground, and remaining signals collecting contact is respectively as coding contact 8, this moment, one end of above-mentioned coding resistor 6 all linked to each other with common, and the other end then is connected on the different coding contact 8.Embodiment two directly is attached to coding resistor 6 and forms the detector bar that contains correction codes on traditional detector bar, can avoid the loss of calibration bars like this, this detector bar that contains correction codes can either carry out the detection of biological sample, can proofread and correct pick-up unit between detecting again.
The number of coding resistor 6 and pick-up unit have determined to contain the group/cording quantity of the detector bar of correction codes to the accuracy of identification of resistance, under the situation of N coding resistor 6 array combination, can discern the resistance M that just can encode for M
NIndividual correction parameter.In the present invention, the number of selected coding resistor 6 is 1～10, and the resistance of these coding resistors 6 is between 1 Ω～1000k Ω.Consider the factor of encoding precision and cost, selected coding resistor 6 numbers of the present invention are preferably 2～4, and the resistance of these coding resistors 6 is preferably between 100 Ω～200k Ω.The coding resistor 6 that is connected on the contact can adopt known resistance form at present, as direct insertion resistance, SMD resistance or fixed slurry printed resistor or adjustable slurry printed resistor.Direct insertion resistance, SMD resistance and fixed slurry printed resistor have all had fixing resistance before the circuit substrate 1 on installing or printing.Adjustable slurry printed resistor then is by print, install the coding resistor 6 that can adjust resistance for the later stage in advance on circuit substrate 1, detector bar production link in the later stage has distributed sensor sensing things such as enzyme, electron mediator, and determined by sample after the correction codes of the detector bar that this contains correction codes, adjust to be packed in by modes such as laser resistor trimming, etchings again and be used to the resistance of encoding on the calibration bars, make it to meet the predictive encoding Standard resistance range.When selecting direct insertion resistance or SMD resistance for use, the mode that can use outside weldings or conductive adhesive is fixed on coding resistor 6 and realizes on the circuit substrate 1 being electrically connected.When selecting fixed slurry resistance or adjustable slurry resistance for use, can use screen printer print on the circuit substrate 1 that PET sheet, epoxy resin board or phenolics plate that thickness is fit to are constituted.In the preferred embodiment of the present invention, select adjustable slurry resistance for use, this adjustable slurry resistance can use the mode of laser accurate resistance trimming to adjust the resistance of each coding resistor 6, makes each coding resistor 6 meet predetermined Standard resistance range.For fear of the oxidation of coding resistor 6 and the encoding error that causes, the surface of the circuit substrate 1 of the detector bar that contains correction codes of the present invention also is coated with encapsulation emulsion sheet 9 and/or print overlay layer 10, by this encapsulation emulsion sheet 9 or print overlay layer 10 the coding resistor district 3 beyond the coding contact district 2 is encapsulated with relevant conducting objects 7.
In the present embodiment, the shape of described circuit substrate 1 and thickness, particularly insert pick-up unit one end shape should with the slot shape offered on the pick-up unit and size with match, can be irregularly shaped as the shape of circuit substrate 1 for strip, ellipse, raindrop shape or other.The thickness of circuit substrate 1 is between 0.05mm～2mm.Can insert more smoothly for detector bar in the slot of pick-up unit and by its reliable identification, the described circuit substrate 1 of present embodiment is the strip of thickness between 0.2mm～0.4mm.For the ease of pulling and pushing and reading of the detector bar that contains correction codes, in the present embodiment, sampling contact regions 4 and coding contact district 2 should be positioned at the same end of circuit substrate 1, and reaction zone 5 and coding resistor district 3 then are positioned at the other end of circuit substrate 1.
The above-mentioned detector bar that contains correction codes can have two kinds of structures: first reaction zone 5 and sampling contact regions 4 place on the front on positive and negative surface of circuit substrate 1, and coding resistor district 3 and coding contact district 2 then place on the reverse side on positive and negative surface of circuit substrate 1.Referring to Fig. 2 .1a and Fig. 2 .1b.This moment is owing to sample contact regions 4 and coding contact 8 lay respectively on the positive and negative both side surface of circuit substrate 1, therefore before detecting, needing elder generation that the one side of the correction on the circuit substrate 1 is contacted with the metal contact of pick-up unit interface circuit proofreaies and correct promptly: anti-inserting, and again circuit substrate 1 is detected simultaneously to contact with the metal contact of pick-up unit interface circuit afterwards and detect promptly: be just slotting.It two is that reaction zone 5, sampling contact regions 4, coding resistor district 3 and coding contact district 2 all place the front of circuit substrate 1, and makes sampling contact regions 4 identical with residing position on circuit substrate 1, coding contact district 2.Referring to Fig. 2 .2 or Fig. 2 .3.This moment, therefore when detecting, the slot that directly will contain the detector bar insertion pick-up unit of correction codes can be realized proofreading and correct and detecting because sampling contact regions 4 and coding contact 8 are positioned on the surface, the same side of circuit substrate 1.When pick-up unit detects the detector bar insertion that contains correction codes, preferentially with coding contact district 2 pairing coding resistor 6 value reading into the microprocessor, size according to the resistance of coding resistor 6, the varying voltage signal value that the coding contact 8 that is attached thereto returns is delivered to microprocessor after amplifying, microprocessor is handled the voltage signal more than above-mentioned 1 road or 1 tunnel, and calls the correction codes that is stored in this batch detector bar in the pick-up unit in advance according to result.Afterwards, need not the detector bar that contains correction codes is pulled out anti-inserting, and directly with the biological specimen siphon or drip in the reaction zone 5 of this detector bar, pick-up unit begins to detect, pick-up unit carries out showing testing result after the coherent detection.
For can decode above-mentioned calibration bars or contain coding resistor 6 in the detector bar of correction codes, to obtain the correction codes of respective batch, the pick-up unit of the disposable biological sensor detection system that the present invention is designed as shown in Figure 3, comprise shell and be installed in the testing circuit of enclosure, shell is provided with slot, button and display screen; Wherein testing circuit mainly is made up of power circuit, microprocessor, interface circuit and amplifying circuit; Button is connected with microprocessor, and interface circuit is positioned at the slot place on the shell, and interface circuit links to each other with the input end of microprocessor through amplifying circuit, and the output terminal of microprocessor is connected with display screen; In addition, be provided with analog-to-digital conversion module, coding correction module and memory module in the described microprocessor, wherein the input end of analog-to-digital conversion module connects amplifying circuit, and the output terminal of analog to digital conversion circuit connects the input end of coding correction module; Above-mentioned coding correction module is connected with the storer that stores 1 correction codes at least, and the coded message that this coding correction module is passed back according to analog to digital conversion circuit is called the correction codes that is stored in this batch detector bar in the storer in advance.
When calibration bars or the detector bar that contains correction codes inserted the interface circuit of pick-up unit, calibration bars or coding resistor 6 values that contain the detector bar of correction codes were read in by microprocessor via coding contact 8.Microprocessor is according to the size of the resistance of coding resistor 6, the varying voltage signal value that the coding contact 8 that is attached thereto returns is delivered to microprocessor after amplifying, microprocessor is handled the voltage signal more than above-mentioned 1 road or 1 tunnel, and calls the correction codes that is stored in this batch detector bar in the pick-up unit in advance according to result.Afterwards, need not the detector bar that contains correction codes is pulled out anti-inserting, and directly with the biological specimen siphon or drip in the reaction zone 5 of this detector bar, pick-up unit begins to detect, pick-up unit carries out showing testing result after the coherent detection.
This pick-up unit is according to mediator bioelectrochemistry principle, can the detection of biological sample under the control of the microprocessor of built-in testing circuit in component concentrations to be measured.As when detecting blood sugar concentration, when the siphon on the blood contact detection bar reaction zone 5 enters the mouth, can be inhaled into reaction zone 5, in reaction zone 5, glucose oxidase layer is behind contact blood, under the cooperation of mediator, at reaction zone 5 redox reaction takes place with the glucose in the blood, the electronics that produced is transferred on the sample region of contact through conducting objects 7, and is transferred to the metal contact of interface circuit via the contact sample region, produces micro-current.Concentration of glucose in the blood is low, and little electric current is just little; Concentration of glucose height in the blood, little electric current are just big.Little electric current is by interface circuit, and the analog to digital converter of sending into microprocessor after amplifying circuit amplifies is a digital signal with analog signal conversion, calculates blood glucose concentration value according to the corresponding relation of little current value and blood sugar concentration then and shows.
Claims (10)
1. calibration bars comprise body, it is characterized in that: described body mainly is made up of coding resistor district (3) and coding contact district (2) that circuit substrate (1) and circuit substrate (1) are provided with; Wherein coding resistor district (3) comprise the coding resistor (6) more than 1 or 1, and coding contact district (2) comprise 2 or 2 above coding contacts (8); Above-mentioned coding resistor district (3) and coding contact district (2) are communicated with by conducting objects (7), the two ends that are each coding resistor (6) respectively link to each other with 1 coding contact (8), wherein the coding contact (8) of end connection is contact, simulation ground, and the coding contact (8) that the other end connects is the signals collecting contact.
2. calibration bars according to claim 1 is characterized in that: described coding resistor district (3) lays respectively at vertically relative two ends of circuit substrate (1) with coding contact district (2).
3. calibration bars according to claim 1 is characterized in that: shared 1 the public contact, simulation ground of all coding resistors (6).
4. calibration bars according to claim 1 is characterized in that: the number of described coding resistor (6) is 2～4, and the resistance of these coding resistors (6) is between 100 Ω～200k Ω.
5. calibration bars according to claim 1 is characterized in that: described coding resistor (6) is SMD resistance or fixed slurry printed resistor or adjustable slurry printed resistor.
6. the detector bar that contains correction codes, comprise reaction zone (5) and sampling contact regions (4) that circuit substrate (1) and circuit substrate (1) are provided with, be communicated with by the conducting objects (7) that is printed on the circuit substrate (1) between reaction zone (5) and the sampling contact regions (4), it is characterized in that: also be provided with coding resistor district (3) and coding contact district (2) on the described circuit substrate (1); Wherein coding resistor district (3) comprise the coding resistor (6) more than 1 or 1, and coding contact district (2) comprise 2 or 2 above coding contacts (8); Above-mentioned coding resistor district (3) and coding contact district (2) are communicated with by conducting objects (7), the two ends that are each coding resistor (6) respectively link to each other with 1 coding contact (8), wherein the coding contact (8) of end connection is contact, simulation ground, and the coding contact (8) of 1 end connection is the signals collecting contact in addition.
7. the detector bar that contains correction codes according to claim 6 is characterized in that: shared 1 the public contact, simulation ground of all coding resistors (6).
8. the detector bar that contains correction codes according to claim 6 is characterized in that: the number of described coding resistor (6) is 2～4, and the resistance of these coding resistors (6) is between 100 Ω～200k Ω.
9. the detector bar that contains correction codes according to claim 6 is characterized in that: described coding resistor (6) is SMD resistance or fixed slurry printed resistor or adjustable slurry printed resistor.
10. pick-up unit comprises shell and is installed in the testing circuit of enclosure that shell is provided with slot, button and display screen; Wherein testing circuit mainly is made up of power circuit, microprocessor, interface circuit and amplifying circuit; Button is connected with microprocessor, and interface circuit is positioned at the slot place on the shell, and interface circuit links to each other with the input end of microprocessor through amplifying circuit, and the output terminal of microprocessor is connected with display screen; It is characterized in that: be provided with analog-to-digital conversion module, coding correction module and memory module in the described microprocessor, wherein the input end of analog-to-digital conversion module connects the output terminal of amplifying circuit, and the output terminal of analog to digital conversion circuit connects the input end of coding correction module; Above-mentioned coding correction module is connected with the storer that stores 1 correction codes at least, and the coding that this coding correction module is reflected according to the coding contact district (2) that analog to digital conversion circuit is passed back is proofreaied and correct resistance value and called the correction codes that is stored in this batch detector bar in the storer in advance.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100596020A CN102253085A (en) | 2011-03-11 | 2011-03-11 | Correction bar, detector bar with correction code and detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100596020A CN102253085A (en) | 2011-03-11 | 2011-03-11 | Correction bar, detector bar with correction code and detection device |
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| CN103076443A (en) * | 2012-11-05 | 2013-05-01 | 广州万孚生物技术股份有限公司 | Detector capable of discriminating calibration card and calibration card, detection system and method |
| WO2013102448A1 (en) * | 2012-01-06 | 2013-07-11 | 达尔生技股份有限公司 | Biosensor and biomeasurement system |
| CN103901079A (en) * | 2013-12-20 | 2014-07-02 | 杭州世佳电子有限公司 | Test paper with code information and manufacturing method thereof |
| CN107290393A (en) * | 2017-07-31 | 2017-10-24 | 南京鱼跃软件技术有限公司 | A kind of recognition methods of automatic size adjusting |
| CN107389743A (en) * | 2017-06-14 | 2017-11-24 | 广州视源电子科技股份有限公司 | The measurement accuracy detection method and blood testing instrument of a kind of blood testing instrument |
| CN108322131A (en) * | 2017-01-16 | 2018-07-24 | 建准电机工业股份有限公司 | Method for identifying program stored in motor controller and circuit board of motor controller with stored program |
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| CN108322131A (en) * | 2017-01-16 | 2018-07-24 | 建准电机工业股份有限公司 | Method for identifying program stored in motor controller and circuit board of motor controller with stored program |
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