CN200987711Y - Artificial biological pulmonary artery and valve canal - Google Patents
Artificial biological pulmonary artery and valve canal Download PDFInfo
- Publication number
- CN200987711Y CN200987711Y CN 200620175187 CN200620175187U CN200987711Y CN 200987711 Y CN200987711 Y CN 200987711Y CN 200620175187 CN200620175187 CN 200620175187 CN 200620175187 U CN200620175187 U CN 200620175187U CN 200987711 Y CN200987711 Y CN 200987711Y
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- bovine
- jugular vein
- valved conduit
- pulmonary artery
- blood vessel
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Abstract
The utility model discloses an artificial biological pulmonary arterial valved conduit, including a section bovine jugular vein vessel with venous valve, one or two pipes made of the bovine pericardial tissue material are connected to the upper end or both ends of the bovine jugular vein vessel, the external surface of the artificial biological pulmonary arterial valved conduit is coated with a polymer materials layer. The utility model only adopts a section of bovine jugular vein valved conduit, the upper end or both ends are replaced by the biological pipe made of bovine pericardium, at the same time the polymer materials layer is coated on the external surface of pipe, thus can settle the problems in that, only using the bovine jugular vein tissue, the pipe valvular inadequacy results from over strong reaction, severe calcification and easy expansion, and the problem in over adhesion in secondary operation, the long term curative effect can be improved greatly.
Description
Technical field
This utility model relates to the biological pulmonary artery valved conduit of a kind of novel artificial, particularly is used to rebuild artificial bio-membrane's pulmonary artery valved conduit that people's right ventricle-pulmonary artery connects.
Background technology
The congenital heart disease of many complexity, as tetralogy of Fallot, pulmonary atresia, double outlet of right ventricle etc. and the capable Ross operator of aortic disease, all need rebuild right ventricle-pulmonary artery connects, material commonly used has the valved conduit from body-centered bag, foreign material, allogeneic aorta valved conduit, artificial material such as Gore-tex sheet, synthetic. and all there is limitation in these materials, and the Gore-tex sheet generally can not be rebuild valve structure; From the structure of body-centered bag structural belt lobe, effect is undesirable; System pressure is low because the right side is felt concerned about, and blood flow rate is slow, the artificial valve after particularly mechanical prosthetic valve is inserted thromboembolic complication many, especially the less artificial nest long-term effect of internal diameter is not good enough.
In recent years, clinical practice bovine jugular vein valved conduit (BJVC) was rebuild pulmonary artery and was connected with the right ventricle, and bovine jugular vein has venous valve, has natural valve structure, can prevent the blood reflux of relaxing period, and operation initial stage effect is comparatively desirable.But along with following up a case by regular visits to postoperative patient, because the reaction of bovine jugular vein vascular wall tissue heteroplasm is strong, and the one section cattle vein blood vessel internal diameter in venous valve upper end is gradually little, therefore after implantation in case take place and the reaction of pulmonary artery anastomotic stoma place hamartoplasia, in time, has and causes stenosis of right ventricular outflow tract once again.Cause patient to have to face the risk of second operation.Simultaneously, we experimental studies have found that, although adopt same chemical modification handle and effectively calcification handle, the cattle venous blood tube wall that implants is organized and is still shown than same cattle venous valve tissue or the easier generation calcification of bovine pericardial tissue, especially promising obvious in the young animal performance.In addition, because bovine jugular vein wall tensile strength is more weak than bovine pericardial tissue, when pulmonary artery pressure raises, generation jugular wall overdistension is often arranged and causes the venous valve incompetence.Therefore, be restricted, still do not have the ideal outflow tract of right ventricle that is used for so far and plant and change treatment and use the valved conduit substitute product owing to above-mentioned multiple reason makes the clinical practice of bovine jugular vein valved conduit.
The utility model content
Technical problem to be solved in the utility model provides a kind of artificial bio-membrane's pulmonary artery valved conduit, only adopt bovine jugular vein band lobe section of tubing, the biological duct that make with bovine pericardium at its upper end or two ends replaces, add simultaneously and cover the problem that the medical macromolecular materials layer is addressed more than can be well, can greatly improve its effect of using at a specified future date at pipeline external surface.
For solving the problems of the technologies described above, technical solution adopted in the utility model is: a kind of artificial bio-membrane's pulmonary artery valved conduit, comprise one section bovine jugular vein blood vessel that has venous valve, the pipeline that one or two bovine pericardial tissue material is made is connected the upper end or the upper/lower terminal of described bovine jugular vein blood vessel, described artificial bio-membrane's pulmonary artery valved conduit outer surface lining polymer material layer.
Wherein, the long 2.5-6.5cm of described bovine jugular vein blood vessel, internal diameter are 10.0-22.0mm, have in the bovine jugular vein blood vessel that at least one group of lobe leaf thickness is even, a big or small unanimity of shape, symmetry, closed good two leaves or SANYE jugular vein lobe; The described bovine pericardium duct length that is connected bovine jugular vein blood vessel upper end is 3.5-6.5cm, and described bovine jugular vein blood vessel angular vein lobe lower edge is that 3.5-6.5cm or the bovine pericardium duct length that connects bovine jugular vein blood vessel angular vein lobe lower edge are 3.5-6.5cm apart from the length of the one section bovine jugular vein blood vessel in pulmonary artery valved conduit lower end; Described bovine pericardial tissue material and bovine jugular vein blood vessel are handled through chemical modification; Described chemical modification processing method comprises with normal saline or all kinds of isosmotic solution of organizing to the rinsing of fresh bovine jugular vein tubing, fix more than 2 hours for the 0.3-2.5 glutaraldehyde solution or carry out calcification with surfactant or coordination compound or epoxide and handle with concentration; The pipe joint internal diameter that used bovine pericardial tissue material is made is identical with band lobe bovine jugular vein bore; Described polymer material layer is polyester textile or polyester nonwoven film cloth, has markings on the described polymer material layer.
The beneficial effect that this utility model can reach is:
1. rationally, structural design cleverly, both utilized the valve of bovine jugular vein, greatly improved again full bovine jugular vein pipeline biocompatibility not good enough, easily the drawback of calcification takes place;
2. the connecting pipe made of bovine pericardium has excellent biological compatibility, is stitched together with human body pulmonary artery end and has avoided because stronger hamartoplasia reaction causes anastomotic stoma narrow once again;
3. reasonable in design makes pipeline upper and lower end size promptly satisfy the needs of anatomical structure and physiological function, and it is convenient to be convenient to cardiac surgeon's operation technique again, reduces the time of operation technique, has significantly reduced contingent all kinds of related complication;
4. outer surface lining polymer material layer can prevent from making operation once more be convenient to operation owing to the tube wall overdistension takes place in the pulmonary artery pressure rising, valve is closed, and can effectively avoid pipeline outer wall and the excessive adhesion of tissue again.
Description of drawings
Fig. 1 is this utility model embodiment 1 structural representation;
Fig. 2 is this utility model embodiment 2 structural representations;
Fig. 3 is this utility model embodiment 3 structural representations.
The specific embodiment
Consult Fig. 1, be this utility model embodiment 1 artificial bio-membrane's pulmonary artery valved conduit structural representation, the valved conduit 3 that comprises bovine jugular vein preparation with valve, connecting pipe 1,2 with two bovine pericardial material preparations, in the middle of connecting pipe 1,2 is sandwiched in valved conduit 3 in the valve upper end, and be stitched together with suture, whole pipe coats one deck polymer material layer 4 outward.
Consult Fig. 2, be this utility model embodiment 2 structural representations, comprise the valved conduit 3 of the bovine jugular vein preparation with valve 5 and the connecting pipe 2 of bovine pericardial material preparation, connecting pipe 2 is stitched together in valve 5 upper ends and valved conduit 3 usefulness sutures.
Consult Fig. 3, be this utility model embodiment 3 structural representations, the valved conduit 3 ' that comprises bovine jugular vein preparation with valve, connecting pipe 1 ', 2 with two bovine pericardial material preparations, connecting pipe 1 ', 2 is positioned at valved conduit 3 ' two ends, and is stitched together by suture respectively, and bovine jugular vein lobe place outer surface coats one deck macromolecular material 6, be marked with Warning Mark on the polymer material layer, differentiate the position when making things convenient for the doctor to perform the operation rapidly.
In the various embodiments described above, bovine pericardium and bovine jugular vein are all handled through modification, and method comprises with normal saline or all kinds of osmometer solution of organizing to the rinsing of fresh bovine jugular vein tubing, fix more than 2 hours for the 0.3-2.5 glutaraldehyde solution or carry out the calcification processing with surfactant or coordination compound or epoxide with concentration.
Among each embodiment, the long 2.5-6.5cm of bovine jugular vein blood vessel, internal diameter are 10.0-22.0mm, the bovine pericardium duct length that is connected bovine jugular vein blood vessel upper end is 3.5-6.5cm, and described bovine jugular vein blood vessel angular vein lobe lower edge is that 3.5-6.5cm or the bovine pericardium duct length that connects bovine jugular vein blood vessel angular vein lobe lower edge are 3.5-6.5cm apart from the length of the one section bovine jugular vein blood vessel in pulmonary artery valved conduit lower end.
The above is preferred embodiment of the present invention only, is not to be used to limit protection scope of the present invention.
Claims (7)
1, a kind of artificial bio-membrane's pulmonary artery valved conduit, comprise one section bovine jugular vein blood vessel that has venous valve, it is characterized in that, the biological duct that one or two bovine pericardial tissue material is made is connected the upper end or the upper/lower terminal of described bovine jugular vein blood vessel, described artificial bio-membrane's pulmonary artery valved conduit whole outer surface or venous valve place outer surface lining polymer material layer.
2, artificial bio-membrane's pulmonary artery valved conduit according to claim 1, it is characterized in that, the long 2.5-6.5cm of described bovine jugular vein blood vessel, internal diameter are 10.0-22.0mm, have in the bovine jugular vein blood vessel that at least one group of lobe leaf thickness is even, a big or small unanimity of shape, symmetry, closed good two leaves or SANYE jugular vein lobe.
3, artificial bio-membrane's pulmonary artery valved conduit according to claim 1, it is characterized in that, the described bovine pericardium duct length that is connected bovine jugular vein blood vessel upper end is 3.5-6.5cm, and described bovine jugular vein blood vessel angular vein lobe lower edge is that 3.5-6.5cm or the bovine pericardium duct length that connects bovine jugular vein blood vessel angular vein lobe lower edge are 3.5-6.5cm apart from the length of the one section bovine jugular vein blood vessel in pulmonary artery valved conduit lower end.
4, artificial bio-membrane's pulmonary artery valved conduit according to claim 1 is characterized in that, described bovine pericardial tissue material and bovine jugular vein blood vessel are handled through chemical modification.
5, artificial bio-membrane's pulmonary artery valved conduit according to claim 1, it is characterized in that described chemical modification processing method comprises with normal saline or all kinds of isosmotic solution of organizing to the rinsing of fresh bovine jugular vein tubing, fix more than 2 hours for the 0.3-2.5 glutaraldehyde solution or carry out calcification with surfactant or coordination compound or epoxide and handle with concentration.
6, artificial bio-membrane's pulmonary artery valved conduit according to claim 1 is characterized in that, the pipe joint internal diameter that used bovine pericardial tissue material is made is identical with band lobe bovine jugular vein bore.
7, artificial bio-membrane's pulmonary artery valved conduit according to claim 1 is characterized in that, described polymer material layer is polyester textile or polyester nonwoven film cloth, has markings on the described polymer material layer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620175187 CN200987711Y (en) | 2006-12-31 | 2006-12-31 | Artificial biological pulmonary artery and valve canal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620175187 CN200987711Y (en) | 2006-12-31 | 2006-12-31 | Artificial biological pulmonary artery and valve canal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN200987711Y true CN200987711Y (en) | 2007-12-12 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200620175187 Expired - Lifetime CN200987711Y (en) | 2006-12-31 | 2006-12-31 | Artificial biological pulmonary artery and valve canal |
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| CN (1) | CN200987711Y (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8137411B2 (en) | 2010-03-15 | 2012-03-20 | Kemal Schankereli | Thin collagen tissue for medical device applications |
-
2006
- 2006-12-31 CN CN 200620175187 patent/CN200987711Y/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8137411B2 (en) | 2010-03-15 | 2012-03-20 | Kemal Schankereli | Thin collagen tissue for medical device applications |
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| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20071212 |
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| EXPY | Termination of patent right or utility model |