CN1981783A - Nano-bee productf for adjusting immune function and its production - Google Patents
Nano-bee productf for adjusting immune function and its production Download PDFInfo
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- CN1981783A CN1981783A CNA2005101245628A CN200510124562A CN1981783A CN 1981783 A CN1981783 A CN 1981783A CN A2005101245628 A CNA2005101245628 A CN A2005101245628A CN 200510124562 A CN200510124562 A CN 200510124562A CN 1981783 A CN1981783 A CN 1981783A
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Abstract
A nano-class bee product for regulating immunity is prepared from propolis, royal jelly, bee pollen, bee pupa and chitosan proportionally through respectively washing and immersing in technological water at -4-60 deg.C, dissolving, purifying, boiling in water at 50-90 deg.C for 180 min by slow fire, hydrolyzing in acid or alcohol, separating impurities, recovering alcohol, and drying.
Description
Technical field
The present invention relates to a kind of medicines and health protection, medicative diet for food therapy goods of forming with " natural " bee product and animal and plant source elite, especially relate to nanometer honeybee product of a kind of immunity-regulating function and preparation method thereof.
Background technology
Along with science and technology development with rapid changepl. never-ending changes and improvements, bee product is used among the difficult miscellaneous diseases such as diabetes, cardiovascular and cerebrovascular vessel, prostate, cancer more widely, be acknowledged as the medicament that has no side effect fully, but existing bee product is the bee glue product of more single Cheng Ke, exist in various degree that the metal separation technology is relatively poor, content of beary metal is higher, product function can't satisfy the shortcoming of people's multiple requirement.
Summary of the invention
The present invention is in order to solve the weak point in the above-mentioned background technology, nano propolis product of a kind of immunity-regulating function and preparation method thereof is provided, it adopts the nanometer biotechnology structural manufacturing process, the extraction and application medicine is rational to greatest extent can, optimize the effective Cheng Ke of biological activity of compatibility " supercritical " purification by liquid extraction, health care, medicative diet for food therapy dual-use function are arranged for inhibition brain atrophy, hyperlipidemia, diabetes, prostate.
For achieving the above object, the technical solution used in the present invention is:
A kind of nanometer goods of immunity-regulating function, its special character is to comprise following component: propolis 5-50 gram, Lac regis apis 10-45 gram, bee pollen 15-40 gram, chitosan 4-10 gram, Pupa Apis 8-25 gram.
A kind of nanometer goods of immunity-regulating function, its special character is to comprise following component: water-soluble bee glue 20-50 gram, purification Lac regis apis 20-45 gram, selected Herba leucadis ciliatae honeybee 15-40 gram, Pupa Apis 8-25 gram, chitosan 4-10 gram.
A kind of nanometer honeybee product of immunity-regulating function is characterized in that comprising following component: water-soluble bee glue 20-45 gram, purification Lac regis apis lyophilized powder 25-40 gram, selected bee pollen 30-40 gram, chitosan 10-15 gram, Pupa Apis 8-25 gram.
A kind of nanometer honeybee product of immunity-regulating function is characterized in that comprising following component: bee glue purifying 30-45 gram, Lac regis apis lyophilized powder 25-40 gram, bee pollen 20-35 gram, chitosan 6-9 gram, Pupa Apis 8-25 gram.
Above-mentioned propolis is a water solublity, and the royal jelly lyophilized powder of Lac regis apis for purifying, bee pollen are the elaboration that fresh water (FW) is removed the heavy metal foreign material, and chitosan is meant that marine organisms extract effective Cheng Ke, and Pupa Apis is the Tinea Apis extract of condition in the environment purification.
A kind of manufacture method of Nano type natural biological albumen honeybee product, its special character is to comprise following operating procedure: respectively divide into groups respectively with-4 ℃ of-60 ℃ of fresh water (FW)s affiliated, cleaning and dipping, dissolving, purification, 180 minutes water treatment when with 50 ℃-90 ℃ of temperature fire being respectively again, the acid of assembly special process, pure hydrolysis separate invalid Cheng Ke, receive ethanol to doing, handle each prescription with biomembrane, eliminate the Fructus Citri tangerinae resistance, separate being harmful to into gram.
Above-mentioned steps comprises: each component is treated to refining raw material earlier, selected, dehydration, freezing, dry, grind, handle with the nanotechnology ultra micro, the change in polarity movement velocity is designed to 18-32 hundred million/second, 4 ℃-65 ℃ of control temperature, time 150-3000 minute, concentrate the high-speed jet atomization drying again.
Above-mentioned end product is the slow controlled-release target capsule preparations of Nano type, pill, suppository, tablet, granule, medicated wine, sugared preparation, health promoting beverage preparation, medicative diet for food therapy goods.
Compared with prior art, the advantage and the effect that have of the present invention is as follows:
1, honeybee product and the synthetic protein of medicine for adopting nanotechnology ultrastructure technology, supercritical to purify in the main prescription of the present invention, helps, makes medicine clear and definite at monarch, minister in the prescription, and dosage is accurate.
2, pharmacology compatibility conditioning during the present invention carries out successively, removing medicine has antagonism, is beneficial to the pharmacology coordinative role and special procures the flavour of a drug composition of prescription, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, principle-method-recipe-medicines.Pay attention to biological activity and efficiently utilize, and the specific part of optimized choice medicine is in the hope of optimum medicine efficacy, outstanding key property, typing rationally, quantitatively.
3, the present invention is according to innovative design novel composing prescription in China's Chinese medicine, aspect pharmacological effect, take into account science, novelty, feasibility and benefit, adopt modern nano biological new technique, new technology, new thing source, new device group to become brand-new modern high technology product.
According to disease have emergency, disease have the exterior and the interior, people have old children situation, actual achievement adopt unique slow controlled release nanometer filmogen on different dosage, the property of medicine, drug effect, the technology of the package, thereby it is required to adapt to various patients.
4, the present invention is with reference to the Chinese Pharmacopoeia treating both the principal and secondary aspects of a disease, and scientific composition to seven immunization therapies and auxiliary treatment effects such as brain atrophy, cardiovascular and cerebrovascular disease, malignant neoplastic disease, diabetes, endocrine disturbance, neurasthenias, is of value to slow down aging, nourishing the brain and improving intelligence.Provide a new treatment technology again to diabetes, cardiovascular and cerebrovascular disease, malignant neoplastic disease, hypertension, hepatitis etc.
The specific embodiment
Below be
Embodiment 1:
Get propolis 40 grams, Lac regis apis 30 grams, bee pollen 15 grams, Pupa Apis 10 grams, chitosan 5 grams.
Embodiment 2:
Water intaking soluble bee glue 30 grams, purification Lac regis apis 25 grams, selected bee pollen 20 grams, Pupa Apis 15 grams, chitosan 10 grams.
Embodiment 3:
Water intaking soluble bee glue 26 grams, purification Lac regis apis lyophilized powder 23 grams, selected bee pollen 20 grams, Pupa Apis 20 grams, chitosan 19 grams.
Wherein propolis is a water solublity, the royal jelly lyophilized powder of Lac regis apis for purifying, and bee pollen is the elaboration that fresh water (FW) is removed the heavy metal foreign material, and Pupa Apis is the Tinea Apis extract of condition in the environment purification, and chitosan is meant that marine organisms extract effective Cheng Ke.
Processing step comprises:
With above-mentioned each component respectively with-4 ℃ of-60 ℃ of fresh water (FW) cleaning and dipping, dissolving, purification, 180 minutes water treatment when with 50 ℃-90 ℃ of temperature fire being respectively again, the acid of assembly special process, pure hydrolysis, separate invalid element, reclaim ethanol to doing, handle each prescription with biomembrane, eliminate repellence, separate oxious component.
Machine, pill, suppository, tablet, granule, medicated wine, sugared preparation, the machine of health promoting beverage, the medicative diet for food therapy goods of the slow controlled-release target capsule of Nano type.
Claims (8)
1, a kind of nano propolis product of immunity-regulating function is characterized in that comprising following component: propolis 5-50 gram, Lac regis apis 10-45 gram, bee pollen 15-40 gram, Pupa Apis 8-25 gram, chitosan 4-10 gram.
2, a kind of nanometer honeybee product of immunity-regulating function is characterized in that comprising following component: water-soluble bee glue 20-50 gram, purification Lac regis apis 20-45 gram, selected bee pollen 15-40 gram, Pupa Apis 8-25 gram, chitosan 4-10 gram.
3, a kind of nanometer honeybee product of immunity-regulating function is characterized in that comprising following component: water-soluble bee glue 20-45 gram, purification Lac regis apis lyophilized powder 25-40 gram, selected bee pollen 30-40 gram, Pupa Apis 8-25 gram, chitosan 4-10 gram.
4, a kind of nanometer honeybee product of immunity-regulating function is characterized in that comprising following component: bee glue purifying 30-45 gram, Lac regis apis lyophilized powder 25-40 gram, bee pollen 20-35 gram, chitosan 6-9 gram, Pupa Apis 8-25 gram.
5, according to the nano propolis product of claim 1,2,3,4 described a kind of immunity-regulating functions, it is characterized in that: propolis is a water solublity, the royal jelly lyophilized powder of Lac regis apis for purifying, bee pollen is the elaboration that fresh water (FW) is removed the heavy metal foreign material, Pupa Apis is the Tinea Apis extract of condition in the environment purification, and chitosan is meant that marine organisms extract effective Cheng Ke.
6, a kind of manufacture method of nano propolis product of immunity-regulating function, it is characterized in that: with described each component respectively with-4 ℃ of-60 ℃ of fresh water (FW)s, cleaning and dipping, dissolving, purification, 180 minutes water treatment when with 50 ℃-90 ℃ of temperature fire being respectively again, the acid of assembly special process, pure hydrolysis separate invalid Cheng Ke, receive ethanol to doing, handle each prescription with biomembrane, eliminate antagonism, separate being harmful to into gram.
7, the manufacture method of the nano propolis product of a kind of immunity-regulating function according to claim 6, it is characterized in that comprising following operating procedure: each component is treated to refining raw material by above-mentioned steps, selected, dehydration, freezing, dry, grind, handle with the nanotechnology ultra micro, the change in polarity movement velocity is designed to 18-32 hundred million/second, 4C-65 ℃ of control temperature, time 150-3000 minute, concentrate the high-speed jet atomization drying again.
8, the nano propolis product manufacture method of a kind of immunity-regulating function according to claim 7 is characterized in that: described end product is the slow controlled-release target capsule preparations of Nano type, pill, suppository, tablet, granule, medicated wine, sugared preparation, health promoting beverage preparation, medicative diet for food therapy goods.
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CNA2005101245628A CN1981783A (en) | 2005-12-16 | 2005-12-16 | Nano-bee productf for adjusting immune function and its production |
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CNA2005101245628A CN1981783A (en) | 2005-12-16 | 2005-12-16 | Nano-bee productf for adjusting immune function and its production |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101564511B (en) * | 2009-05-05 | 2012-05-09 | 武兴战 | Natural protein product for treating diabetes and manufacture method |
CN103798751A (en) * | 2014-03-07 | 2014-05-21 | 南华县咪依噜天然食品开发有限责任公司 | Truffle nutritional tablets |
CN110973553A (en) * | 2019-12-23 | 2020-04-10 | 南京圣诺生物科技实业有限公司 | Propolis nutritional composition for enhancing immunity and application thereof |
-
2005
- 2005-12-16 CN CNA2005101245628A patent/CN1981783A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101564511B (en) * | 2009-05-05 | 2012-05-09 | 武兴战 | Natural protein product for treating diabetes and manufacture method |
CN103798751A (en) * | 2014-03-07 | 2014-05-21 | 南华县咪依噜天然食品开发有限责任公司 | Truffle nutritional tablets |
CN110973553A (en) * | 2019-12-23 | 2020-04-10 | 南京圣诺生物科技实业有限公司 | Propolis nutritional composition for enhancing immunity and application thereof |
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