CN1883534A - Medicine for treating orthopaedics disease and preparation method thereof - Google Patents
Medicine for treating orthopaedics disease and preparation method thereof Download PDFInfo
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- CN1883534A CN1883534A CNA2006100127898A CN200610012789A CN1883534A CN 1883534 A CN1883534 A CN 1883534A CN A2006100127898 A CNA2006100127898 A CN A2006100127898A CN 200610012789 A CN200610012789 A CN 200610012789A CN 1883534 A CN1883534 A CN 1883534A
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Abstract
The invention relates to a Chinese medicinal composition for treating orthopaedic diseases, which is prepared from dipsacus root, frankincense, myrrh, drynaria, native copper, wood louse, Chinese angelica root and safflower as raw material through the steps of disintegrating, mixing homogeneously, and loading into capsules, sterilizing and disinfecting.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of orthopaedics, particularly relating to a kind of is the Chinese patent medicine of the treatment orthopaedics of feedstock production with Chinese medicine.The invention still further relates to the preparation method of this medicine.
Background technology
Orthopaedic disease be clinically more see because of external force or a kind of disease interior thereby that cause, on treatment technology, multiple treatment means is arranged at present, also obtained certain curative effect, but great majority just can be obtained curative effect under various treatments cooperatively interact the situation for the treatment of, some patient can not cure for a long time.Some drug price height commonly used, curative effect is long, and cure rate is low.Reach 200,000,000 crowd according to relevant report China osteopathia patient, increase 8,000 ten thousand osteopathia patients every year approximately newly.Clinically except that operative treatment, still there is not ideal Drug therapy at present.But operative treatment has a big risk, the expense height; Traction is massaged, and acupuncture and moxibustion therapy is cured the symptoms, not the disease; At drug treatment,, can not effect a permanent cure though the pain relieving of western medicine energy can only block nerves be conducted; Conventional medicament for oral administration is easy to generate drug resistance, is difficult to prove effective; Though outer emplastrum such as GUZHIZENGSHENG YITIELING curative effect are fine, owing to adopt rubber mass, penetration is relatively poor relatively, is difficult for reaching effective blood concentration; Though tradition plaster affinity, penetration are strong, the leaded heavy metal substance that waits of its substrate does not meet modern preparation requirement.
Summary of the invention
The purpose of this invention is to provide a kind of promoting blood circulation by removing blood stasis, the Chinese Traditional Medicines of blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, dredge the meridian passage, anti-inflammatory analgetic, the strong marrow of benefit bone, treating both the principal and secondary aspects of a disease.
Another goal of the invention of the present invention provides the preparation method of this medicine.
The preparation method of this medicine is provided, and is another goal of the invention of the present invention.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to orthopaedic disease, with reference to modern pharmacological research, according to clinical experience for many years, control to debate to execute, " cure the wound and do not forget blood stasis dispelling; blood stasis dispelling must be invigorated blood circulation earlier, blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, dredge the meridian passage, anti-inflammatory analgetic, the strong marrow of benefit bone ".
Medicine of the present invention specifically is to be made by the raw material of following weight ratio:
Radix Dipsaci 20～40 Olibanums 5～20 Myrrhas 5～20 Rhizoma Drynariae 20～40
Pyritum 10～35 Eupolyphaga Seu Steleophagas 15～35 Radix Angelicae Sinensis 15～40 Flos Carthamis 10～15.
The formula optimization weight proportion scope of preparation medicine of the present invention is:
Radix Dipsaci 25～35 Olibanums 8～15 Myrrhas 8～15 Rhizoma Drynariae 25～35
Pyritum 15～25 Eupolyphaga Seu Steleophagas 20～30 Radix Angelicae Sinensis 20～35 Flos Carthamis 11～14.
The optimum weight proportioning of medicine of the present invention is:
Radix Dipsaci 30 Olibanums 10 Myrrhas 10 Rhizoma Drynariae 30
Pyritum 20 Eupolyphaga Seu Steleophagas 25 Radix Angelicae Sinensis 30 Flos Carthamis 12.
Above-mentioned each component can be made said dosage form on any pharmaceutics, and the preferred dosage form of the present invention is a capsule.
Above-mentioned each component is made medicine production method of the present invention is: above-mentioned various Chinese medicine pulverize separately are become 100～150 order fine powders, and according to above-mentioned parts by weight mix homogeneously, in incapsulating, sterilization makes the capsule product.
In the prescription of the present invention: the Radix Dipsaci acrid in the mouth has the effect of reunion of bone; Olibanum is arduous, treats all malignant boil, the granulation promoting pain relieving; Myrrha is warm in nature flat, pain relieving, promoting blood circulation to remove obstruction in the collateral; Rhizoma Drynariae is warm in nature, can change the effect of chondrocyte function, postponement skeleton degeneration, reduction osteoarthritis sickness rate; Pyritum is arduous flat, goes into Liver and kidney warp, energy eliminating stasis to stop pain, reunion of bone; Eupolyphaga Seu Steleophaga is salty-cold, slightly poisonous, goes into Liver Channel, can search and cut accumulation of blood one by one, broken congestion, reuniting the fractured tendons and bones; The Radix Angelicae Sinensis sugariness, but the hemopoietic reinforcing the heart, hold up empty function of mending damage, dissipating blood stasis for subsidence of swelling, nourishing blood and promoting granulation; Flos Carthami have invigorate blood circulation, function such as collateral dredging, change silt, tissue regeneration promoting.
Above drug combination has the promote osteogenesis growth and repairs; Can promote revascularization, recover the blood flow and the nutrition supply of ischemia osseous tissue; But induced osteogenesis cell and chondroblast generate, and a large amount of synthetic bone tissue, thereby promote that callus generates, maturation, quicken the healing of fracture and bone does not connect.
All medicines share, and also have invigorating the kidney and strengthening the bones, expelling wind and removing dampness, and blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, the function of channels sootheing and network vessel quickening has the growth of the osteoclast of promotion, is adjusted to osteocyte and osteoclast balance; Regulate calcium metabolism; Regulate neural, vascular function and softening, dissolving, the efficacy of a drug injury of can going directly is gone the stasis of blood, and pain is ended, swollen disappearing, bone closes.
Curable substance all kinds fracture of the present invention is (as comminuted, compressibility etc.), the fracture of parts of body is (as rib, pelvis, neck of femur etc.), and disease such as meniscus injury, synovitis, congenital sacral hiatus, osteomyelitis, regardless of age size, medical history length, sclerotin, all can cure.
For showing the therapeutic effect of medicine of the present invention to orthopaedics, the present invention has carried out clinical observation on the therapeutic effect to 680 routine orthopedics patients, wherein: male's 450 examples, women's 230 examples, the age is 2 years old-84 years old; Wherein slight fracture patient 450 examples, old fracture 190 examples, comminuted fracture 40 examples.
Efficacy determination: 2-35 year slight fracture patient clinical observation 450 examples, take and can fully recover in this medicine 20-40 days; Old fracture 190 examples, 40 years old-84 years old patient took this medicine 2-3 after individual month, and through the clinical examination film making, the fracture healing is cured 187 examples, effective 3 examples; Comminuted fracture 40 examples, 20-45 year, take this medicine 2-3 month after, cure 39 examples, effective 1 example.
Process is carried out comprehensive statistics to 680 routine clinical observation patients, clinical cure rate 99.2%, and effective percentage 100% is not found toxic and side effects and untoward reaction in clinical observation.
Curative effect performance in the therapeutic process:
It is 2-7 days the earliest that curative effect occurs, and general pain alleviates gradually, and swelling disappears, and slight fracture patient is taken the i.e. recovery from illness after month of this medicine, and can be movable; For the patient with severe symptoms of old or the comminuted fracture i.e. recovery from illness in 2-3 month of taking medicine,, do not stay sequela through follow-up observation.
Table 1 clinical drug therapeutic effect statistics of the present invention
(the age: 2-84 year)
| The course of treatment | Effect | Clinical manifestation (number) | ||
| Slight fracture | Old (disunion) fracture | Comminuted fracture | ||
| 450 | 190 | 40 | ||
| 30 days | Clinical cure | 450 | ||
| Effectively | ||||
| Invalid | ||||
| 100 days | Clinical cure | 187 | 39 | |
| Effectively | 3 | 1 | ||
| Invalid | ||||
The specific embodiment
Embodiment 1:
Take by weighing raw material by following weight (part) proportioning:
Radix Dipsaci 60g Olibanum 10g Myrrha 10g Rhizoma Drynariae 60g
Pyritum 20g Eupolyphaga Seu Steleophaga 30g Radix Angelicae Sinensis 60g Flos Carthami 15g.
Concrete production method is:
Above-mentioned various Chinese medicine pulverize separately are become 100 order fine powders, and according to above-mentioned parts by weight mix homogeneously, in the 1# capsule of packing into, sterilization makes the capsule product.
Embodiment 2:
Take by weighing raw material by following weight (part) proportioning:
Radix Dipsaci 70g Olibanum 12g Myrrha 12g Rhizoma Drynariae 70g
Pyritum 25g Eupolyphaga Seu Steleophaga 35g Radix Angelicae Sinensis 70g Flos Carthami 15g.
Concrete production method is:
Above-mentioned various Chinese medicine pulverize separately are become 120 order fine powders, and according to above-mentioned parts by weight mix homogeneously, in the 1# capsule of packing into, sterilization makes the capsule product.
Claims (6)
1, a kind of medicine for the treatment of orthopaedic disease is characterized in that: it is the medicament of being made by following materials based on weight
Radix Dipsaci 20～40 Olibanums 5～20 Myrrhas 5～20 Rhizoma Drynariae 20～40
Pyritum 10～35 Eupolyphaga Seu Steleophagas 15～35 Radix Angelicae Sinensis 15～40 Flos Carthamis 10～15.
2, the medicine of treatment orthopaedic disease according to claim 1 is characterized in that: wherein the weight proportion of each raw material is:
Radix Dipsaci 25～35 Olibanums 8～15 Myrrhas 8～15 Rhizoma Drynariae 25～35
Pyritum 15～25 Eupolyphaga Seu Steleophagas 20～30 Radix Angelicae Sinensis 20～35 Flos Carthamis 11～14.
3, the medicine of treatment orthopaedic disease according to claim 1 is characterized in that: wherein the weight proportion of each raw material is:
Radix Dipsaci 30 Olibanums 10 Myrrhas 10 Rhizoma Drynariae 30
Trionyx sinensis Wiegmann worm 25 Radix Angelicae Sinensis 30 Flos Carthamis 12 on the Pyritum 20.
4, according to the medicine of claim 1,2 or 3 described treatment orthopaedic diseases, it is characterized in that: described medicament is a said dosage form on any pharmaceutics.
5, the medicine of treatment orthopaedic disease according to claim 4 is characterized in that: described medicament is a capsule.
6, the preparation method of the medicine of the described treatment orthopaedic disease of claim 5 is characterized in that: above-mentioned various Chinese medicine pulverize separately are become 100～150 order fine powders, and according to above-mentioned parts by weight mix homogeneously, in incapsulating, sterilization makes the capsule product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CNA2006100127898A CN1883534A (en) | 2006-05-22 | 2006-05-22 | Medicine for treating orthopaedics disease and preparation method thereof |
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| CNA2006100127898A CN1883534A (en) | 2006-05-22 | 2006-05-22 | Medicine for treating orthopaedics disease and preparation method thereof |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101361772B (en) * | 2008-08-22 | 2011-05-18 | 玉林市骨科医院 | Oral medicine for treating traumatic injury and production method thereof |
| CN102430005A (en) * | 2010-09-29 | 2012-05-02 | 赵丙雪 | Traditional Chinese medicinal honeyed pill for treating bone fracture |
| CN102579605A (en) * | 2012-03-12 | 2012-07-18 | 高永学 | Oral Chinese medicinal composition for treating bone fracture diseases |
| CN102631458A (en) * | 2012-03-06 | 2012-08-15 | 周茂泰 | Teasel root powder for dredging governor meridian |
| CN102805793A (en) * | 2012-08-30 | 2012-12-05 | 申丕勇 | Oral Chinese medicinal pill for treating osteomyelitis |
| CN103550456A (en) * | 2013-11-22 | 2014-02-05 | 简厚奎 | Drug for treating bone diseases |
| CN106492022A (en) * | 2016-11-25 | 2017-03-15 | 安徽珂欣茧业有限公司 | A kind of bone-knitting Chinese medicament formula handed down from one's ancestors and preparation method thereof |
| CN107661363A (en) * | 2016-07-28 | 2018-02-06 | 陈立新 | Synthetism particle |
| CN111407794A (en) * | 2020-04-17 | 2020-07-14 | 韩燚迪 | Plaster for treating bone diseases |
| CN111529584A (en) * | 2020-06-23 | 2020-08-14 | 段景怡 | A Chinese medicinal composition for treating fracture, arthritis and acute and chronic soft tissue injury, and its preparation method |
| CN112843169A (en) * | 2021-03-05 | 2021-05-28 | 刘金海 | Bone-knitting medicine and preparation method and application thereof |
| CN113633737A (en) * | 2021-06-25 | 2021-11-12 | 河北医科大学第二医院 | Composition for repairing injury of synovial tissue of knee joint and preparation method thereof |
| CN115414418A (en) * | 2022-09-06 | 2022-12-02 | 田利珍 | Multifunctional plaster and preparation method thereof |
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2006
- 2006-05-22 CN CNA2006100127898A patent/CN1883534A/en active Pending
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101361772B (en) * | 2008-08-22 | 2011-05-18 | 玉林市骨科医院 | Oral medicine for treating traumatic injury and production method thereof |
| CN102430005A (en) * | 2010-09-29 | 2012-05-02 | 赵丙雪 | Traditional Chinese medicinal honeyed pill for treating bone fracture |
| CN102430005B (en) * | 2010-09-29 | 2013-05-08 | 翟慎华 | Traditional Chinese medicinal honeyed pill for treating bone fracture |
| CN102631458A (en) * | 2012-03-06 | 2012-08-15 | 周茂泰 | Teasel root powder for dredging governor meridian |
| CN102579605A (en) * | 2012-03-12 | 2012-07-18 | 高永学 | Oral Chinese medicinal composition for treating bone fracture diseases |
| CN102805793A (en) * | 2012-08-30 | 2012-12-05 | 申丕勇 | Oral Chinese medicinal pill for treating osteomyelitis |
| CN102805793B (en) * | 2012-08-30 | 2014-01-29 | 申丕勇 | Oral Chinese medicinal pill for treating osteomyelitis |
| CN103550456B (en) * | 2013-11-22 | 2015-09-09 | 简厚奎 | A kind of medicine for the treatment of bone disease |
| CN103550456A (en) * | 2013-11-22 | 2014-02-05 | 简厚奎 | Drug for treating bone diseases |
| CN107661363A (en) * | 2016-07-28 | 2018-02-06 | 陈立新 | Synthetism particle |
| CN106492022A (en) * | 2016-11-25 | 2017-03-15 | 安徽珂欣茧业有限公司 | A kind of bone-knitting Chinese medicament formula handed down from one's ancestors and preparation method thereof |
| CN111407794A (en) * | 2020-04-17 | 2020-07-14 | 韩燚迪 | Plaster for treating bone diseases |
| CN111529584A (en) * | 2020-06-23 | 2020-08-14 | 段景怡 | A Chinese medicinal composition for treating fracture, arthritis and acute and chronic soft tissue injury, and its preparation method |
| CN112843169A (en) * | 2021-03-05 | 2021-05-28 | 刘金海 | Bone-knitting medicine and preparation method and application thereof |
| CN113633737A (en) * | 2021-06-25 | 2021-11-12 | 河北医科大学第二医院 | Composition for repairing injury of synovial tissue of knee joint and preparation method thereof |
| CN115414418A (en) * | 2022-09-06 | 2022-12-02 | 田利珍 | Multifunctional plaster and preparation method thereof |
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