CN1839786A - Bathing solution for disinfection and skin-protection - Google Patents
Bathing solution for disinfection and skin-protection Download PDFInfo
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- CN1839786A CN1839786A CN 200610045766 CN200610045766A CN1839786A CN 1839786 A CN1839786 A CN 1839786A CN 200610045766 CN200610045766 CN 200610045766 CN 200610045766 A CN200610045766 A CN 200610045766A CN 1839786 A CN1839786 A CN 1839786A
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- skin
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- disinfection
- triclosan
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Abstract
Disclosed is a bath lotion for skin care and sterilization, which is prepared from Triclosan 0.1-0.5%, alcohol 13-20%, glycerin 0.5-3%, methyl glycol 30-45%, gourmet powder 0.1-0.5%, and water 38-50%. The preparation process comprises the steps of dissolving Triclosan into ethanol, mixing glycerine and methyl glycol, stirring homogeneously, then dissolving the miscible liquid into water, stirring homogeneously, charging in perfume compound, stirring homogeneously again.
Description
Technical field: the invention is to be used for antipruritic fast, sterilization, especially eliminates the shower skin care liquid of staphylococcus aureus, Candida albicans.
Background technology: along with the progressively raising of people's living standard, after SARS epidemic and bird flu particularly occurring, people's self-disinfection sterilization consciousness of self-protection constantly strengthens, take regular shower mode maybe after motion, work, because of fine hair hole expansion can be by bacterial infection, can sufferings, thereby adopt the shower mode to eliminate sufferings, sterilization, the skin care liquid of using always before during shower, the cost of manufacture height has increased burden to consumer.Sterilization effect is not obvious simultaneously.
Summary of the invention: the purpose of the invention provides the tangible bathing solution for disinfection and skin-protection of a kind of sterilization effect, especially effectively eliminates staphylococcus aureus, Candida albicans; The purpose of the invention is achieved through the following technical solutions:
Bathing solution for disinfection and skin-protection: its prescription and percentage by weight are:
Triclosan 0.1～0.5%;
Ethanol 13～20%;
Glycerol 0.5～3%;
Propylene glycol 30～45%;
Essence 0.1～0.5%;
Water 38～50%.
Its processing technology is: triclosan is dissolved in the ethanol, glycerol, mixed with propylene glycol are stirred, two kinds of mixed liquors are separately dissolved in the water again, stir, add essence again, stir.
Its technology preparation principle is; this utility model is to be main component with the triclosan aqueous solution; it is formulated to add Derma-Guard, skin moisturizing agent and essence etc. again; triclosan is the powder of aroma type white; be dissolved in multiple organic solvent; strong acid and strong base and heat are had high stability, are not infected with skin and product, kill widely and inhibitory action causing that infection or pathogenicity Gram-positive and negative bacterium, fungus, yeast and virus etc. all have, the skin nonirritant.Glycerol is commonly called as glycerol, is the pleasantly sweet thick liquid of no color or smell, can be miscible with water, also can be dissolved in organic solvents such as ether, chloroform, have strong hygroscopicity, in this product be solvent be again lubricant.Ethanol, water white transparency, flammable liquid is made solvent in this agent.Essence as additive, is used to change this agent fragrance, and kind is selected as required.
The advantage of the invention is: the prescription and the percentage by weight that constitute bathing solution for disinfection and skin-protection are reasonable, and it is easy to add processing technology, has therefore reduced cost of manufacture, has reduced the burden of consumer; Because employing triclosan aqueous solution is as antiseptic sterilization agent and utilize propylene glycol, glycerol skin care effect, so when shower, use this skin bath-lotion, tangible sterilization effect is arranged, and skin is played a protective role, this skin bath-lotion is 92.84% to the average bacteriostasis rate of staphylococcus aureus especially, is 91.40% to the oidiomycetic average bacteriostasis rate of white; Simultaneously, to escherichia coli, acarid is antibacterial obviously; This skin bath-lotion has the high-efficiency broad spectrum antibiotic property, and skin pruritus, dermatitis, the tinea manuum, tinea corporis and cruris, head pruritus etc. are had positive effect.Mosquito bite also there is better curative effect.
The specific embodiment: bathing solution for disinfection and skin-protection: its prescription and percentage by weight are:
Triclosan 0.1～0.5%;
Ethanol 13～20%;
Glycerol 0.5～3%;
Propylene glycol 30～45%;
Essence 0.1～0.5%;
Water 38～50%.
Its processing technology is: triclosan is dissolved in the ethanol, with glycerol, mixed with propylene glycol, stir respectively, two kinds of mixed liquors are dissolved in the water again, stir, add essence again, stir promptly.
Its concrete example of making: with 100 kilograms of finished products is example:
1,0.3 kilogram of triclosan is dissolved in 15 kilograms of the ethanol and stir evenly, 37 kilograms of propylene glycol are mixed stirring evenly with glycerol for 2 kilograms, again two kinds of mixed liquors are dissolved in 45.5 kilograms in the water and stir, add 0.2 kilogram in essence at last, stir promptly.
2,0.1 kilogram of triclosan is dissolved in 20 kilograms of the ethanol and stir evenly, 35 kilograms of propylene glycol are mixed stirring evenly with glycerol for 0.5 kilogram, again two kinds of mixed liquors are dissolved in 44.3 kilograms in the water and stir, add 0.1 kilogram in essence at last, stir promptly.
3,0.5 kilogram of triclosan is dissolved in 17 kilograms of the ethanol and stir evenly, 41 kilograms of propylene glycol are mixed stirring evenly with glycerol for 3 kilograms, again two kinds of mixed liquors are dissolved in 38 kilograms in the water and stir, add 0.5 kilogram in essence at last, stir promptly.
4,0.2 kilogram of triclosan is dissolved in 17.5 kilograms of the ethanol and stir evenly, 30 kilograms of propylene glycol are mixed stirring evenly with glycerol for 2 kilograms, again two kinds of mixed liquors are dissolved in 50 kilograms in the water and stir, add 0.3 kilogram in essence at last, stir promptly.
5,0.4 kilogram of triclosan is dissolved in 20 kilograms of the ethanol and stir evenly, 39.4 kilograms of propylene glycol are mixed stirring evenly with glycerol for 2 kilograms, again two kinds of mixed liquors are dissolved in 38 kilograms in the water and stir, add 0.2 kilogram in essence at last, stir promptly.
6,0.4 kilogram of triclosan is dissolved in 13 kilograms of the ethanol and stir evenly, 45 kilograms of propylene glycol are mixed stirring evenly with glycerol for 1.5 kilograms, again two kinds of mixed liquors are dissolved in 39.7 kilograms in the water and stir, add 0.4 kilogram in essence at last, stir promptly.
The resulting bathing solution for disinfection and skin-protection of above-mentioned example has tangible sterilization effect, is 92.84% to staphylococcus aureus bacteriostasis rate average rate especially, is 91.40% to the oidiomycetic average bacteriostasis rate of white, and is antibacterial obviously to escherichia coli, acarid simultaneously; Also have the high-efficiency broad spectrum antibiotic property, skin pruritus, dermatitis, the tinea manuum, tinea corporis and cruris, head pruritus etc. are had positive effect.
Provide examining report below:
Bathing solution for disinfection and skin-protection stability is measured (bacteriostasis property):
1, test strain title, bacterial strain number, the unit of providing and cultivate algebraically: staphylococcus aureus (Staphylococcusaureus) AS 1.2465; ATCC; The 6th～7 generation of=ATCC 6538 (China Committee for Culture Collection of Microorganisms common micro-organisms center).
2, prescription: 0.3 kilogram of triclosan, 15 kilograms of ethanol, 37 kilograms of propylene glycol, 2 kilograms of glycerol, 45.5 kilograms in water, 0.2 kilogram in essence.
3, detect foundation:
State Standard of the People's Republic of China's " disposable use hygienic article sanitary standard " GB15979-2002;
2.1.11.3.4 (1) .2 of Ministry of Health of the People's Republic of China's " disinfection technology standard " (version in 2002)) and 2.1.1.2.3 (1).
4, preservation condition:
The test method accelerated test
Package encapsulation situation Packing Sound
Preserve 54 ℃ ± 1 ℃ of ambient temperature
Preserve envionmental humidity 75% ± 5%
14 days standing times
5, the temperature of testing environment and relative humidity:
19 ℃ ± 2 ℃ of testing environment room temperatures
Testing environment relative humidity 45% ± 5%
6, test
Test temperature is 20 ℃ ± 1 ℃, and test repeats 3 times.Deposit back (accelerated test: 54 ℃ ± 1 ℃ of laying temperature, relative humidity 75% ± 5%, 14 days standing times), bathing solution for disinfection and skin-protection effective ingredient, concentration are stock solution, be 10min action time, is 90.85% to the average bacteriostasis rate of staphylococcus aureus.
| Deposit situation | The test sequence number | The average bacteriostasis rate (%) of effect different time (min) | The average clump count of positive controls (cfu/ml) | |||
| 2 | 5 | 10 | 20 | |||
| Before depositing | 1 | 82.15 | 88.94 | 92.10 | 94.63 | 3.80×10 4 |
| 2 | 83.61 | 86.77 | 94.93 | 97.03 | 5.90×10 4 | |
| 3 | 81.40 | 89.23 | 91.53 | 98.07 | 4.60×10 4 | |
| Meansigma methods | 82.38 | 88.31 | 92.84 | 96.58 | 4.10×10 4 | |
| After depositing | 1 | 80.15 | 85.94 | 90.10 | 95.63 | 3.80×10 4 |
| 2 | 81.61 | 86.77 | 91.93 | 94.03 | 5.90×10 4 | |
| 3 | 82.00 | 87.23 | 90.53 | 93.07 | 2.60×10 4 | |
| Meansigma methods | 81.25 | 86.65 | 90.85 | 94.24 | 4.10×10 4 | |
7, conclusion
According to State Standard of the People's Republic of China's " disposable use hygienic article sanitary standard " GB15979-2002, test temperature is 20 ℃ ± 1 ℃, and test repeats 3 times.Deposit back (accelerated test: 54 ℃ ± 1 ℃ of laying temperature, relative humidity 75% ± 5%, 14 days standing times), bathing solution for disinfection and skin-protection effective ingredient, concentration are stock solution, be 10min action time, is 90.85% to the average bacteriostasis rate of staphylococcus aureus.Has strong bacteriostasis.
Bathing solution for disinfection and skin-protection is to the staphylococcus aureus bacteriostatic test:
1, test strain title, bacterial strain number, the unit of providing and cultivate algebraically: staphylococcus aureus (Staphvlococcusaureus) AS 1.2465; ATCC; The 5th～6 generation of=ATCC 6538 (China Committee for Culture Collection of Microorganisms common micro-organisms center).
2, prescription: 0.3 kilogram of triclosan, 15 kilograms of ethanol, 37 kilograms of propylene glycol, 2 kilograms of glycerol, 45.5 kilograms in water, 0.2 kilogram in essence.
3, detect foundation:
State Standard of the People's Republic of China's " disposable use hygienic article sanitary standard " GB15979-2002:
The 2.1.1.2.3 (1) of Ministry of Health of the People's Republic of China's " disinfection technology standard " (version in 2002).
4, test
Test temperature is 20 ℃ ± 1 ℃, and test repeats 3 times.Bathing solution for disinfection and skin-protection effective ingredient, concentration are stock solution, and be 10min action time, are 92.84% to the average bacteriostasis rate of staphylococcus aureus.
| The test sequence number | The average bacteriostasis rate (%) of effect different time (min) | The average clump count of positive controls (cfu/ml) | |||
| 2 | 5 | 10 | 20 | ||
| 1 | 82.15 | 88.94 | 92.10 | 94.63 | 3.80×10 4 |
| 2 | 83.61 | 86.77 | 94.93 | 97.03 | 5.90×10 4 |
| 3 | 82.38 | 88.31 | 92.85 | 96.58 | 4.60×10 4 |
| Meansigma methods | 82.38 | 88.31 | 92.84 | 96.58 | 4.10×10 4 |
5, conclusion
According to State Standard of the People's Republic of China's " disposable use hygienic article sanitary standard " GB15979-2002, test temperature is 20 ℃ ± 1 ℃, and test repeats 3 times.Bathing solution for disinfection and skin-protection effective ingredient, concentration are stock solution, and be 10min action time, are 92.84% to the average bacteriostasis rate of staphylococcus aureus.Has strong bacteriostasis.
Bathing solution for disinfection and skin-protection is to the Candida albicans bacteriostatic test:
1, test strain title, bacterial strain number, the unit of providing and cultivate the 6th～7 generation of algebraically: Candida albicans (Candidaalbicans) ATCC 10231 (China Committee for Culture Collection of Microorganisms common micro-organisms center).
2, prescription: 0.3 kilogram of triclosan, 15 kilograms of ethanol, 37 kilograms of propylene glycol, 2 kilograms of glycerol, 45.5 kilograms in water, 0.2 kilogram in essence.
3, detect foundation:
State Standard of the People's Republic of China's " disposable use hygienic article sanitary standard " GB15979-2002;
The 2.1.1.9.3 (1) of Ministry of Health of the People's Republic of China's " disinfection technology standard " (version in 2002).
4, test
Test temperature is 20 ℃ ± 1 ℃, and test repeats 3 times.Bathing solution for disinfection and skin-protection effective ingredient, concentration are stock solution, and be 10min action time, are 91.40% to the oidiomycetic average bacteriostasis rate of white.
| The test sequence number | The average bacteriostasis rate (%) of effect different time (min) | The average clump count of positive controls (cfu/ml) | |||
| 2 | 5 | 10 | 20 | ||
| 1 | 78.63 | 86.12 | 90.04 | 96.25 | 5.80×10 4 |
| 2 | 80.59 | 85.04 | 91.95 | 96.10 | 6.10×10 4 |
| 3 | 81.95 | 84.95 | 92.21 | 97.80 | 4.60×10 4 |
| Meansigma methods | 80.72 | 85.37 | 91.40 | 96.72 | 5.50×10 4 |
5, conclusion
According to State Standard of the People's Republic of China's " disposable use hygienic article sanitary standard " GB15979-2002, test temperature is 20 ℃ ± 1 ℃, and test repeats 3 times.Bathing solution for disinfection and skin-protection effective ingredient, concentration are stock solution, and be 10min action time, are 91.40% to the oidiomycetic average bacteriostasis rate of white.Has strong bacteriostasis.
Claims (1)
1, bathing solution for disinfection and skin-protection: it is characterized in that: bathing solution for disinfection and skin-protection prescription and percentage by weight are:
Triclosan 0.1～0.5%;
Ethanol 13～20%;
Glycerol 0.5～3%;
Propylene glycol 30～45%;
Essence 0.1～0.5%;
Water 38～50%;
Its processing technology is: triclosan is dissolved in the ethanol, glycerol, mixed with propylene glycol are stirred, two kinds of mixed liquors are separately dissolved in the water again, stir, add essence again; Stir.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610045766 CN1839786A (en) | 2006-01-26 | 2006-01-26 | Bathing solution for disinfection and skin-protection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610045766 CN1839786A (en) | 2006-01-26 | 2006-01-26 | Bathing solution for disinfection and skin-protection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1839786A true CN1839786A (en) | 2006-10-04 |
Family
ID=37029097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610045766 Pending CN1839786A (en) | 2006-01-26 | 2006-01-26 | Bathing solution for disinfection and skin-protection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1839786A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101731213B (en) * | 2009-12-18 | 2013-08-07 | 江苏省河浪生物科技有限公司 | Production process of disinfection mould-proof liquid |
| CN112076121A (en) * | 2020-09-14 | 2020-12-15 | 可帮(天津)高新技术有限公司 | Skin lotion and its production process |
| CN112438258A (en) * | 2019-09-04 | 2021-03-05 | 诗乐氏实业（深圳）有限公司 | Compound disinfectant and preparation method thereof |
-
2006
- 2006-01-26 CN CN 200610045766 patent/CN1839786A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101731213B (en) * | 2009-12-18 | 2013-08-07 | 江苏省河浪生物科技有限公司 | Production process of disinfection mould-proof liquid |
| CN112438258A (en) * | 2019-09-04 | 2021-03-05 | 诗乐氏实业（深圳）有限公司 | Compound disinfectant and preparation method thereof |
| CN112076121A (en) * | 2020-09-14 | 2020-12-15 | 可帮(天津)高新技术有限公司 | Skin lotion and its production process |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
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